Welcome to this course on systems biology,
so I am Karthik Raman from biotech, I work
in the area of systems biology so this is
my area of research and over the next few
classes we will try to cover various aspects
of systems biology.
I will talk you through it as we go on with
the slides.
So the first module will be introduction to
mathematical modelling so we will just have
an intro of what models are, how do the model
systems in general and so on, followed by
this we will look at static networks, so this
is more or less graph theory, but graph theory
is used in biology in different ways, so we
will be looking at graph theory, how graph
theory is being used in biology and so on.
And then we will talk about reconstruction
of biological networks and databases and tools
for systems biology, so this is a bunch of
methods and tools and databases that are very
important for doing any of the other things
in the course, right, so if you want to resort
to static --How do you... where do you get
the static networks if you want to analyze
them or is there a place where you can find
dynamic models of biological systems, right.
Where do you get all the metabolic networks
if you want to analyze later on in the course,
right, so we will then move to dynamic modelling
of biological systems followed by metabolic
network analysis and constraint based analysis.
Finally we will touch upon gene regulatory
circuits and signalling networks and then
a bunch of very interesting advanced topics
in systems biology.
We will try to touch up on whole sale modelling,
we will try to study a few other interesting
things like how do you estimate the robustness
of biological systems or how evolvable are
biological systems and so on.
So these are some of the things that we will
be trying to look at.
