Drug Used in Bronchial Asthma
Classification Of Drugs:
1.Bronchodilators
2.Leukotriene pathway inhibitors
3.Mast cell stabilizers
4.Corticosteroids
5.Anti IgE antibody
1.Bronchodilators
A.B agonist:
a.Selective B2 agonist-----
Short acting (duration 4-6 hours)
Sulbutamol
Terbutaline
Bambuterol
Long Acting (duration 12 hours or more)
Salmeterol
Formeterol
Fenoterol
Rimeterol
b.Non selective (B1+B2) agonist:
(Adrenaline)
Ephedrine
Isoprenaline
B.Methyl xanthine:
Theophylline
Aminophylline
Doxophylline
C.Anticholinergics:
Ipratropium bromide
Tiotropium bromide
Oxitropium
2.Leukotriene pathway inhibitors:
Montelukast
Zafirlukast
Zileuton
3.Mast cell stabilizers:
Sodium cromoglycate
Ketotifen
4.Corticosteroides:
Systemic:
Hydrocortisone
Prednisolone
Inhalational:
Beclomethasone
Budesonide
Fluticasone
5.Anti IgE antibody:
Omalizumab
Rational Approach for Asthma
*Use of bronchodilator.
*Use of drug which prevents release
of mediators from mast cell.
*Use of drug which removes
inflammatory state of the bronchial tree.
*Other non drug measures must also be taken.
