- What is up ZPac?
It's your boy, ZDoggMD.
Check it out, I'm live
and direct at the office.
I've got my wife's gear behind me
because I'm trying to pretend to be a,
you know a smart radiologist
whereas I'm in fact, just a
just a hospitalist who cares!
Okay, I care too much
particularly about pseudoscience
which I'm gonna talk about today.
The MTHFR mutation
and how anti-vaccine lunatics
are trying to spin it as something
that actually matters to vaccination.
Spoiler alert.
It doesn't.
In fact, there's tons of pseudoscientists
and quacks all over the internet
from chiropractors to naturopaths
who are claiming that this mutation
has something to do with a supplement
or a thingamajigger they can sell you
to make money off of your
scientific lack of knowledge.
So we're gonna remedy that right now.
What is MTHFR?
It is methylene tetrahydrofolate reductase
or mother(BEEP), for short.
It is a essential sort of cofactor enzyme.
It's encoded by DNA in the
production of glutathione,
in homocysteine and folate metabolism
and other rather complex pathways
that we don't need to get into the body.
Bottom line is mutations,
and there are many different ones,
in the gene that encodes the MTHFR enzyme,
can cause reductions in its function,
not on or off
but really some spectrum
of a reduction that's functional
which means you get less folate, right?
More homocysteine builds up
and these can cause a variety of problems.
For example,
folate deficiency can
cause pregnancy-related
neural tube defects.
High levels of homocysteine that build up
when you have a mutation in this,
can cause things like blood clots,
venous thromboembolism,
et cetera.
Now it turns out these
mutations are fairly common.
I, in fact, have a particular
homozygous mutation.
But here's the deal.
If your folate levels are normal
or you're taking folate supplements
or eating a pretty high folate diet,
none of this typically will matter.
We don't screen for this mutation.
We don't worry about it
unless homocysteine levels are elevated
or folate levels are low
and it can affect other B vitamins,
technically, as well.
So this is an easily
treatable sort of deficiency.
Not typically a big deal.
We don't often test or screen for it
and yet, this sort of
pseudoscience community
has taken this thing,
latched onto it
because there's tons of like
these little associational studies,
poor quality,
that they cherry-pick,
ignoring the data to the contrary.
One of,
you know so they'll say it causes autism.
If you have MTHFR mutations,
you shouldn't be vaccinated
because you don't detoxify
because glutathione is an
important detoxifying agent.
They have no idea what that means.
So you'll see quacks
all over the internet,
in particular, it's become this mythology
in the anti-vaccine
community, the antivaxxers
which apparently, according
to the writer of Aladdin,
is the equivalent of saying the N word
'cause it's such as stigma.
Yeah, it should be.
All right.
They have taken this and run with it
for no good reason
because the bottom line is
simple supplementation can
treat symptomatic mutation
meaning you have low levels of folate,
et cetera.
It has nothing to do with vaccination.
There's no good data, actually,
that it has to do with
a lot of other stuff.
More studies are
necessary for those things
but the bottom line is
if you're using that
as a reason not to vaccinate,
you're just absolutely wrong.
Like many things that
have scientific names
and complex words involved
like methylene tetrahydrofolate reductase,
the quacks online have taken these words
and try to use them against us,
mostly to sell you stuff.
So bottom line is share this video
with people that you've
seen that are like,
well, I have MTHFR
and I won't vaccinate.
I'm like, uh, son,
I'm homozygous for one of the mutations
that only 10% of the population has.
By the way, there's tons of
mutations in the population,
it's not uncommon at all.
And I'm fully vaccinated.
I'm only mostly toxic
and my children who are likely carriers
are fully vaccinated.
It has nothing to do with vaccines
and very little to do
with a lot of other stuff
which is why we typically
don't test for it.
Hope this helps.
Have fun with the stuff, guys.
Make fun of these people.
They're dumb!
And they're trying to hurt you
and take your money.
All right.
On that note, I'm gonna take your money.
Become a supporter.
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that sort of thing and we out.
Peace.
