
****ABOUT ISHLT

2016-2017 BOARD OF DIRECTORS

ISHLT STAFF

2017 ANNUAL MEETING SCIENTIFIC PROGRAM COMMITTEE

2017 ABSTRACT REVIEWERS

ISHLT COMMITTEE ROSTERS

Corporate Development Committee

Education Committee

Governance Committee

Grants and Awards Committee

International and Inter-Society Coordination Committee (I2C2)

ISHLT Mechanically Assisted Circulatory Support (IMACS®) Registry Steering Committee

International DCD Registry Steering Committee

International Pediatric Heart Failure Registry (IPHFR) Steering Committee

International Thoracic Transplant Registry Steering Committee

Journal of Heart and Lung Transplantation (JHLT) Editorial Board

Registries and Databases Committee

Standards and Guidelines Committee

Links Newsletter Editorial Staff

ISHLT SCIENTIFIC COUNCIL OPERATING BOARDS

Basic Science and Translational Research

Chronic Thromboembolic Pulmonary Hypertension

Heart Failure and Transplantation

Infectious Diseases

Junior Faculty and Trainee

Mechanical Circulatory Support

Nursing, Health Sciences and Allied Health

Pathology

Pediatric Thoracic Transplantation and Heart Failure

Pharmacy and Pharmacology

Pulmonary Hypertension

Pulmonary Transplantation

PAST PRESIDENTS

PAST PROGRAM CHAIRS

JOURNAL AND LINKS NEWSLETTER EDITORS

REGISTRY MEDICAL DIRECTORS

ISHLT AWARD RECIPIENTS

OUTSTANDING ACHIEVEMENT AWARDS:

ISHLT Pioneer Award

ISHLT Lifetime Achievement Award

ISHLT Lifetime Service Award

Emeritus Membership

GRANTS AND SCHOLARSHIPS:

ISHLT Norman E. Shumway Career Development Award

ISHLT Joel D. Cooper Career Development Award

ISHLT Nursing Research Grant Award

ISHLT Research Fellowship Award

ISHLT Transplant Registry Early Career Award

ISHLT/Bayer Pulmonary Hypertension Research Grant Award

[ISHLT/O.H. Frazier Award in MCS Translational Research Sponsored by Medtronic   
(Formerly ISHLT/O.H. Frazier Award in MCS Translational Research   
Sponsored by Heartware and ISHLT/Heartware Award for Translational Research in MCS)](index_split_011.html#id_Toc478027334)

ISHLT Branislav Radovancevic Memorial Fellowship Grant (Supported by Thoratec)

ISHLT International Traveling Scholarship Award

ISHLT Leach-Abramson-Imhoff Links Travel Awards

ABSTRACT AWARDS:

Philip K. Caves Award

Nursing, Health Sciences & Allied Health Excellence in Research Award

JFTC Clinical Case Dilemmas in Thoracic Transplantation Best Presentation Award

ISHLT Branislav Radovancevic Memorial Best MCSD Paper Award (Supported by Thoratec)

ACCREDIDATION INFORMATION CONTINUING MEDICAL EDUCATION INFORMATION

UNRESTRICTED EDUCATIONAL GRANTS

COMMERCIAL SUPPORT

HIGHLIGHTS OF THE MEETING

Basic Science and Translational Research

Heart Failure and Transplantation

Infectious Diseases

Lung Transplantation

Mechanical Circulatory Support

Nursing, Health Sciences and Allied Health

Pathology

Pediatric Thoracic Transplantation and Heart Failure

Pharmacy and Pharmacology

Pulmonary Hypertension

HOTEL FLOOR PLANS

Lobby Level

2nd Level - Harbor

2nd Level - Seaport

3rd Level - Harbor

3rd Level - Seaport

4th Level

POSTER MAPS

Coronado Poster Hall Wednesday

Harbor Poster Hall Wednesday

Regatta Poster Hall Wednesday

Seaport Poster Hall Wednesday

Coronado Poster Hall Thursday

Harbor Poster Hall Thursday

Regatta Poster Hall Thursday

Seaport Poster Hall Thursday

Coronado Poster Hall Friday

Harbor Poster Hall Friday

Regatta Poster Hall Friday

Seaport Poster Hall Friday

ACRONYMS

SCIENTIFIC COUNCIL MEETINGS & NETWORKING RECEPTIONS

DAILY SCHEDULE

Monday, April 3, 2017

Tuesday, April 4, 2017

Wednesday, April 5, 2017

Thursday, April 6, 2017

Friday, April 7, 2017

Saturday, April 8, 2017

WEDNESDAY ANNUAL MEETING SCIENTIFIC PROGRAM APRIL 05, 2017

SYMPOSIUM 01: Joint ISHLT/ICCAC Symposium: Besides the Surgery - How to Make VAD Patients Successful

SYMPOSIUM 02: When Should We Call It Quits? The Efficacy of Interventions to Ameliorate Psychosocial Risk Factors

SYMPOSIUM 03: Primary Graft Dysfunction (PGD) and Vasoplegia After Heart Transplantation: Sink or Swim

SYMPOSIUM 04: Thinking Outside the Box: Extra-Pulmonary Management in Lung Transplantation

SYMPOSIUM 05: Joint ISHLT/PHA Symposium: PH and Transplant: Where Do We Go From Here?

SYMPOSIUM 06: The Failing Fontan - Where Do We Go From Here?

SYMPOSIUM 07: Joint ISHLT/ESCMID Symposium: Ongoing Challenges in Transplant Infectious Diseases

OPENING PLENARY SESSION

ORAL SESSION 01: Too Thick or Too Thin? Bleeding and Thrombosis in MCS

ORAL SESSION 02: Engineering for Perfection in MCS

ORAL SESSION 03: Moving DCD Forward: Thinking Inside the Box

ORAL SESSION 04: Donor Lung Allocation Strategies

ORAL SESSION 05: Registries and Risk Scores in Pulmonary Hypertension: Updates, Lessons Learned, and Practice Changes

ORAL SESSION 06: Pediatric Heart Failure: Diagnosis, Management, and Confronting Risk

ORAL SESSION 07: Cutting Edge Updates in Infectious Diseases

ORAL SESSION 08: Bugs and Devices: A Bad Combination

ORAL SESSION 09: MCS Surgery: Does Nuance Make a Master?

ORAL SESSION 10: Movement on the Heart Transplant Wait List: VADS, Exceptions and Antibodies

ORAL SESSION 11: Improving Prognosis in Chronic Lung Allograft Dysfunction

ORAL SESSION 12: Innovation in Pediatric MCS

SYMPOSIUM 08: ECMO in Pre-Capillary PH: What is the Best Option for My Patient?

SYMPOSIUM 09: JHLT at ISHLT: The Year in a Capsule

MINI ORAL SESSION 1: Complicating Factors in MCS

MINI ORAL SESSION 2: Donor Evaluation and Management: DBD and DCD

MINI ORAL SESSION 3: Wretched Strangers: Mechanisms of Thoracic Organ Infection, Rejection and Tolerance

MINI ORAL SESSION 4: Allocation, Bridging and Lung Allograft Assessment Strategies

MINI ORAL SESSION 5: The Hardware of MCS

MINI ORAL SESSION 6: Therapeutics in Advanced Heart and Lung Disease

THURSDAY **** ANNUAL MEETING SCIENTIFIC PROGRAM APRIL 06, 2017

SUNRISE SYMPOSIUM 01: Walk With Me: Exercise Physiology in the LVAD Patient

SUNRISE SYMPOSIUM 02: Chagasic Cardiomyopathy: Lessons To Be Learned

SUNRISE SYMPOSIUM 03: Lifecycle Journey of Thrombosis in Mechanical Circulatory Support Patients

SUNRISE SYMPOSIUM 04: Completing the Picture: Patient Reported Outcomes (PROs) as an Essential Source of Information in Evaluating Transplantation Outcomes

SUNRISE SYMPOSIUM 05: Upcoming Opportunities and Challenges in Pediatric Lung Transplantation

SUNRISE SYMPOSIUM 06: "Those Darn CARVs": Community Acquired Respiratory Viruses in Lung Transplant

SYMPOSIUM 10: Antibodies in Mechanical Circulatory Support: The Phantom Menace

SYMPOSIUM 11: Not CAVing to CLADtastrophy: Emerging Mechanisms of Chronic Heart and Lung Allograft Disease

SYMPOSIUM 12: A Tale of Two Organs: Selecting and Managing Multi-Organ Transplant Recipients

SYMPOSIUM 13: Lung Allocation Scores (LAS): Making the Complex Simple, or Just the Simple Complex?

SYMPOSIUM 14: Chronic Thromboembolic Pulmonary Hypertension (CTEPH): Current Controversies and New Directions

SYMPOSIUM 15: HLA, AMR and DSA - Approaching Antibodies in Kids

SYMPOSIUM 16: "Around the World in 80 Days": Infectious Challenges in Cardiothoracic Transplantation

PLENARY SESSION

ORAL SESSION 13: Contemporary LVAD Trials - Same Old Song or New Tune?

ORAL SESSION 14: Measure for Measure: In- and Ex-Vivo Cellular and Molecular Approaches for Thoracic Organ Tailoring

ORAL SESSION 15: Therapies and Monitoring After Heart Transplantation

ORAL SESSION 16: The Rise of the Machines: ECLS and EVLP in Lung Transplantation

ORAL SESSION 17: What's Up Next in Pulmonary Hypertension Research?

ORAL SESSION 18: Contemporary Challenges in Pediatric Heart Transplant

ORAL SESSION 19: Junior Faculty Clinical Case Dilemmas in Thoracic Transplantation: The Best of the Best

SYMPOSIUM 17: To Pulse or Not To Pulse? That is the Question

SYMPOSIUM 18: Weeding Out Fact from Fiction - the Highs and Lows of Marijuana Use in Transplant

SYMPOSIUM 19: Cardiogenic Shock: Types, Teams and Tactics

SYMPOSIUM 20: ECMO in Lung Transplantation: Sensational Success or Fantastic Failure?

SYMPOSIUM 21: Cardiopulmonary Hemodynamics, the Right Ventricle, and the Kidney: Connecting All the Dots

SYMPOSIUM 22: Let's Get Personal! Precision Diagnostics in Thoracic Transplantation

SYMPOSIUM 23: Taming of the Shrew: Mycobacterium Abscessus in Lung Transplantation

MINI ORAL SESSION 7: Factors that Drive Success in MCS

MINI ORAL SESSION 8: Infections, Induction and IVIG

MINI ORAL SESSION 9: Novel Strategies and Mechanisms in Lung Preservation, Heart Failure and Assist Devices

MINI ORAL SESSION 10: Challenges in Lung Transplantation

MINI ORAL SESSION 11: Outcomes in MCS

MINI ORAL SESSION 12: Hot Topics in Pediatric Heart Transplantation

FRIDAY **** ANNUAL MEETING SCIENTIFIC PROGRAM APRIL 07, 2017

SUNRISE SYMPOSIUM 07: Getting to the Heart of Muscular Dystrophies

SUNRISE SYMPOSIUM 08: Live Long and Prosper: Thriving After Pediatric Transplantation

SUNRISE SYMPOSIUM 09: Mixed Rejection (MR) of the Cardiac Allograft: The Next Frontier

SUNRISE SYMPOSIUM 10: Contrasts and Similarities in Children and Adults: IPAH, Portopulmonary Hypertension, and Perioperative Management

SUNRISE SYMPOSIUM 11: There is No Such Thing as Perfect: Selecting Recipients for Lung Transplantation

SUNRISE SYMPOSIUM 12: HIV and Transplantation: It Isn't Going Away...

ORAL SESSION 20: New and Improving? Evolving Outcomes with MCS

ORAL SESSION 21: New Fixes for an Old Problem: Preventing, Diagnosing, and Treating Pump Thrombosis

ORAL SESSION 22: Does Risk Reap Reward? Expanding the Heart Donor Pool

ORAL SESSION 23: Choosing Right: Lung Recipient Selection and Management

ORAL SESSION 24: An Amalgamation of Support in Heart Failure

ORAL SESSION 25: Improving Outcomes in Pediatric Lung Transplantation

ORAL SESSION 26: Philip K. Caves Award Candidate Presentations

ORAL SESSION 27: The Leaking Gut - New Strategies for GI Bleeding in MCS

ORAL SESSION 28: The Heart of the Matter: Cardiac Substrate in MCS Therapy

ORAL SESSION 29: Donor Utilization and Allocation in Heart Transplantation: Lessons to Learn

ORAL SESSION 30: Novel Mechanisms in Chronic Lung Allograft Dysfunction

ORAL SESSION 31: Saved by the Bell: Overcoming Adherence and Frailty

ORAL SESSION 32: The Tell Tale Heart: From Signals to Biomarkers

ORAL SESSION 33: PATH to Better Outcomes: Diagnostics in Heart and Lung Transplantation

SYMPOSIUM 24: Aiming Off Target: Non-Cardiac Consequences of LVAD Support

SYMPOSIUM 25: Dealing with Antibodies Before and After Heart Transplant: Do We Have New Arrows in our Quiver?

SYMPOSIUM 26: Making Every Heart Count

SYMPOSIUM 27: Bench to Bedside: How Advances in Immunology Shape the Care of Today's Lung Transplant Recipients

SYMPOSIUM 28: Great Debates in Pulmonary Hypertension

SYMPOSIUM 29: How to Mend a Broken Heart: Approaches for Cardiac Regeneration

SYMPOSIUM 30: E-Health, Wearables, Social Media and Big Data in Transplantation: Fancy Toys or True Care Innovations?

ORAL SESSION 34: Short-Term MCS for Shock: New Paradigms

ORAL SESSION 35: Heart Failure in MCS

ORAL SESSION 36: CAV: New Insights to an Old Problem

ORAL SESSION 37: Impact of Donor Characteristics on Lung Transplant Outcomes

ORAL SESSION 38: The Nightmare of Primary Cardiac Allograft Dysfunction

ORAL SESSION 39: Early Career Scientist Award in Transplantation Finalist Presentations

ORAL SESSION 40: Drugs, Bleeding and Enzymes ... Oh My!

MINI ORAL SESSION 13: Controversies in Heart Transplantation

HTX, MCS

MINI ORAL SESSION 14: Recipient Risk Factors Affecting Outcome after Lung Transplantation

MINI ORAL SESSION 15: Pediatric Heart Failure, MCS, and Peri-Transplant Issues

MINI ORAL SESSION 16: Assessing and Managing the Failing Right Ventricle

MINI ORAL SESSION 17: Progress in MCS Outcomes

MINI ORAL SESSION 18: Patient Centered Outcomes in Advanced Heart and Lung Disease

SATURDAY **** ANNUAL MEETING SCIENTIFIC PROGRAM APRIL 08, 2017

SUNRISE SYMPOSIUM 13: Mechanical Circulatory Support - The Interface of Design and Outcome

SUNRISE SYMPOSIUM 14: The Tsunami of Adult Congenital Heart Disease (ACHD) Patients Who Need Advanced Therapies: Are We Prepared?

HTX, HF, LTX, MCS, PEDS, PH

SUNRISE SYMPOSIUM 15: Extracorporeal Photopheresis: Shedding Light on Rejection?

SUNRISE SYMPOSIUM 16: Pregnant - Scared? So Are We.... Management of Pregnancy in Our Complex Patients

SUNRISE SYMPOSIUM 17: Living in a 'Bacterial' World: Microbiome in Thoracic Transplantation

ORAL SESSION 41: The Rhythm is Going to Get You: EP Issues in MCS

ORAL SESSION 42: The Weighting Game: Impact of Obesity, Age, and Other Comorbidities in MCS

ORAL SESSION 43: In the Mix of Heart Failure

ORAL SESSION 44: Optimizing Early Outcomes after Lung Transplantation

ORAL SESSION 45: Heart Transplant in Special Populations

ORAL SESSION 46: Rogue One: A Graft Wars Story of Rejection and Tolerance

PLENARY SESSION

ORAL SESSION 47: Not the Usual Suspects: Driving Outcomes in MCS

ORAL SESSION 48: Seeing the Patient Beyond the Device

ORAL SESSION 49: Antibodies and Other Determinants of Cardiac Rejection: Let's ROCK and Rho

ORAL SESSION 50: Influencing Long-term Outcomes in Lung Transplantation

ORAL SESSION 51: Optimizing Outcomes After Heart Transplantation: Predictors and Risk Scores

ORAL SESSION 52: Does Size Matter? Center Volume, Urgency Status and Managing Complications

ORAL SESSION 53: Getting to the Heart of the Matter: Psychosocial Factors Predict Outcomes in Transplant and MCS

WEDNESDAY POSTER SESSION 1 APRIL 05, 2017

Heart Failure

Heart Transplantation

Infectious Diseases

Mechanical Circulatory Support

Pediatrics

Junior Faculty Clinical Case Reports

THURSDAY POSTER SESSION 2 APRIL 06, 2017

Economics, Ethics, Public Policy

Heart Transplantation

Lung Transplantation

Mechanical Circulatory Support

Nursing, Health Sciences, Allied Health

Pulmonary Hypertension

Pharmacy & Pharmacology

FRIDAY POSTER SESSION 3 APRIL 07, 2017

Basic Science & Translational Research

Heart Transplantation

Lung Transplantation

Mechanical Circulatory Support

Pathology

Junior Faculty Clinical Case Reports

ISHLT ACADEMY: CORE COMPETENCIES IN INFECTIOUS DISEASES IN THORACIC TRANSPLANTATION AND MCS SCIENTIFIC PROGRAM

ISHLT ACADEMY: CORE COMPETENCIES IN MECHANICAL CIRCULATORY SUPPORT SCIENTIFIC PROGRAM

ISHLT ACADEMY: CORE COMPETENCIES IN PEDIATRIC AND ADULT CONGENITAL MECHANICAL CIRCULATORY SUPPORT SCIENTIFIC PROGRAM

ISHLT ACADEMY: MASTER CLASS IN MECHANICAL CIRCULATORY SUPPORT SCIENTIFIC PROGRAM

ISHLT ACADEMY: MASTER CLASS IN PULMONARY HYPERTENSION

AFFILIATE EVENTS

CORPORATE EVENTS AND INDUSTRY THEATERS LISTINGS

EXHIBIT HALL FLOOR PLAN

2017 EXHIBITORS AND BOOTH NUMBERS

2017 EXHIBITOR PRODUCT DESCRIPTIONS

FUTURE ANNUAL MEETINGS

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# ABOUT ISHLT

The International Society for Heart and Lung Transplantation (ISHLT) is a not-for-profit, multidisciplinary, professional organization dedicated to improving the care of patients with advanced heart or lung disease through transplantation, mechanical support and innovative therapies via research, education and advocacy.

ISHLT was created in 1981 at a small gathering of about 15 cardiologists and cardiac surgeons. Today we have over 3000 members from over 45 countries, representing over 15 different professional disciplines involved in the management and treatment of end-stage heart and lung disease. This multinational, multidisciplinary mix is one of the biggest strengths of the Society. It brings greater breadth and depth to our educational offerings and provides an exceptional environment for networking and exchanging information on an informal basis.

Our members include anesthesiologists, basic scientists, cardiologists, cardiothoracic surgeons, ethicists, immunologists, nurses, pathologists, perfusionists, pharmacists, pulmonologists, tissue engineers, transplant coordinators, and infectious disease specialists. Despite their differing specializations, all ISHLT members share a common dedication to the advancement of the science and treatment of end-stage heart and lung disease.

The purposes of the Society are:

  1. To associate persons interested in the fields of heart and lung transplantation, end-stage heart and lung disease, and related sciences.
  2. To encourage and stimulate basic and clinical research in these disciplines and to promote new therapeutic strategies.
  3. To hold scientific meetings featuring presentations and discussions relevant to these disciplines.
  4. To sponsor a scientific journal for the publication of manuscripts related to these disciplines.
  5. To establish and maintain an international registry for heart and lung transplantation.
  6. To award research grants and establish endowments for the study of these disciplines

# 2016-2017 BOARD OF DIRECTORS

Maryl R. Johnson, MD, President, University of Wisconsin, Madison, WI

Andrew J. Fisher, FRCP PhD, President-Elect, Freeman Hospital, Newcastle Upon Tyne, United Kingdom

R. Duane Davis, MD, MBA, Past President, Florida Hospital, Orlando, FL

Joseph Rogers, MD, Secretary-Treasurer, Duke University Medical Center, Durham, NC

Christian Benden, MD FCCP, Director, University Hospital Zurich, Zurich, Switzerland

Jason D. Christie, MD, Director, University of Pennsylvania, Philadelphia, PA

Lara Danziger-Isakov, MD, MPH, Director, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Tobias Deuse, MD, PhD, Director, University of California at San Francisco, San Francisco, CA

Howard J. Eisen, MD, Director, Drexel University College of Medicine, Philadelphia, PA

Stephan M. Ensminger, MD, DPhil, Director, Ruhr-University Bochum, Bad Oeynhausen, Germany

Daniel J. Goldstein, MD, Director, Montefiore Medical Center, Bronx, NY

Peter M. Hopkins, FRACP, Director, The Prince Charles Hospital, Brisbane, Australia

Michael G. Petty, PhD, RN, CNS, Director, University of Minnesota Medical Center, Minneapolis, MN

Jeffrey J. Teuteberg, MD, Director, University of Pittsburgh/Presbyterian, Pittsburgh, PA

Dirk Van Raemdonck, MD, PhD, Director, University Hospital Gasthuisberg, Leuven, Belgium

Ex Officio Board Members

Mandeep R. Mehra, MD, MBBS, FACC, FACP, Editor-in-Chief _Journal of Heart and Lung Transplantation_

Josef Stehlik, MD, MPH, International Thoracic Transplant Registry Medical Director

Christopher H. Wigfield, MD, FRCS (C/Th), Medical Director of Educational Affairs

Amanda W. Rowe, ISHLT Executive Director

# ISHLT STAFF

Amanda W. Rowe

Executive Director

Phyllis Glenn

Director of Membership Services

Lisa Edwards

Director of Meetings

Lee Ann Mills

Director of Operations

Susie Newton

Communications Manager

Megan Barrett

Communications Assistant

Justin Hickman

Finance and Operations Assistant

14673 Midway Road, Suite 200

Addison, TX 75001

Phone: 972-490-9495

Fax: 972-490-9499

www.ISHLT.org

# 2017 ANNUAL MEETING SCIENTIFIC PROGRAM COMMITTEE

◊ Symposium Planning Committee

• Abstract Selection Committee

Jeffrey J. Teuteberg, MD, Pittsburgh, PA, USA, 2017 Program Chair ◊ •

Maryl R. Johnson, MD, Madison, WI, USA ISHLT President ◊ •

Andrew J. Fisher, FRCP, PhD, Newcastle Upon Tyne, UK, 2016 Program Chair ◊ •

Christian Benden, MD, FCCP, Zurich, Switzerland, 2018 Program Chair ◊ •

Saima Aslam, MD, MS, San Deigo, CA, USA ◊ •

Fiorella Calabrese, MD, Padova, Italy ◊ •

Chesney Castleberry, MD, St. Louis, MO, USA •

Sabina M. De Geest, RN, PhD, Basel, Switzerland ◊ •

Shashank S. Desai, MD, Falls Church, VA, USA ◊ •

Fabienne Dobbels, MSc, PhD, Leuven, Belgium •

Howard J. Eisen, MD, Philadelphia, PA, USA ◊ •

Maryjane Farr, MD, New York, NY, USA ◊ •

Savitri Fedson, MD, Houston, TX, USA •

Rochelle Gellatly, PharmD, Melbourne, Australia •

Patricia Ging, PharmD, Dublin, Ireland ◊ •

Kristine Guleserian, MD, Dallas, TX, USA •

Christopher Hayward, MD, Sydney, Australia •

Are Martin Holm, MD, PhD, Oslo, Norway ◊ •

Shahid Husain, MD, MS, Toronto, Canada •

Jonathan N. Johnson, MD, Rochester, MD ◊ •

Kiran Khush, MD, Stanford, CA, USA •

Ivan Knezevic, Ljubljana, Slovenia •

Theodoros Kofidis, MD, PhD, FRCS, Singapore, Singapore ◊ •

Brent Lampert, DO, Bexley, OH, USA •

Erika D. Lease, MD, Seattle, WA, USA ◊ •

Claudius Mahr, DO, Seattle, WA, USA •

Tereza Martinu, MD, Toronto, Canada ◊ •

Mandeep R. Mehra, MD, MBBS, FACC, FACP, Boston, MA, USA ◊ •

Hirsch Mehta, MD, San Diego, CA, USA •

Joshua Mooney, MD, Stanford, CA, USA •

Sanem Nalbantgil, MD, Izmir, Turkey ◊ •

Desley Neil, FRCPath, Birmingham, UK ◊ •

Ivan Netuka, MD, PhD, Prague, Czech Republic ◊ •

Francis Pagani, MD, PhD, Ann Arbor, MI, USA ◊ •

Caroline Patterson, MD, Cambridge, UK •

Simon Pecha, MD, Hamburg, Germany ◊ •

Axel Rahmel, MD, Frankfurt, Germany •

Joanna M. Schaenman, MD, PhD, Los Angeles, CA, USA ◊ •

Palak Shah, MD, MS, Falls Church, VA, USA •

Oksana A. Shlobin, MD, Falls Church, VA, USA ◊ •

Michael Shullo, PharmD, Pittsburgh, PA, USA ◊ •

Ryan J. Tedford, MD, Baltimore, MD, USA ◊ •

Adriana Torres, MD, Bogota Colombia •

Marian Urban, MD, Newcastle Upon Tyne, UK ◊ •

C. Dario Vizza, MD, Rome, Italy ◊ •

Robin Vos, MD, PhD, Leuven, Belgium ◊ •

Connie White-Williams, RN, PhD, Birmingham, AL, USA •

Christopher H. Wigfield, MD FRCS(C/Th), Chicago, IL, USA ◊ •

Quincy Young, PhD, RPsych, Vancouver, BC, Canada ◊ •

Roger Yusen, MD, MPH, St. Louis, MO, USA •

Daniel Zimpfer, MD, Vienna, Austria •

# **  
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#  ******2017 ABSTRACT REVIEWERS**

Deepak Acharya, MD, University of Alabama, Birmingham, AL, USA

Rasha Adam, RN, University of Minnesota Medical Center, Minneapolis, MN, USA

Sean Agbor-Enoh, MD, National Institutes of Health, Bethesda, MD, USA

Clemens Aigner, MD, University Clinic Essen, Essen, Germany

Hakim Ali, MD, Duke University, Durham, NC, USA

Larry Allen, MD, MHS, University of Colorado, Denver, CO, USA

Christopher Almond, MD, Stanford University, Stanford, CA, USA

Cristiano Amarelli, MD, Monaldi Hospital, Napoli, Italy

Amrut Ambardekar, MD, University of Colorado, Denver, CO, USA

Allen Anderson, MD, FACC, Northwestern University, Chicago, IL, USA

Annalisa Angelini, MD, University of Padua, Padua, Italy

Samantha Anthony, PhD, MSW, The Hospital for Sick Children, Toronto, ON, Canada

Medhat Askar, MD, PhD, Baylor University Medical Center, Dallas, TX, USA

Estela Azeka, MD, University of Sao Paulo, Sao Paulo, Brazil

Carla Baan, PhD, Erasmus Medical Center, Rotterdam, Netherlands

Dipanjan Banerjee, MD, Stanford University, Stanford, CA, USA

Aditya Bansal, MD, Ochsner Clinic Foundation, New Orleans, LA, USA

David Baran, MD, Newark Beth Israel Medical Center, Newark, NJ, USA

Aliessa Barnes, MD, Children's Mercy Hospital, Kansas City, MO, USA

Markus Barten, MD, PhD, University Heart Center Hamburg, Hamburg, Germany

George Belitsis, MD, Great Ormond Street Hospital, London, United Kingdom

Lavanya Bellumkonda, MD, Yale University School of Medicine, New Haven, CT, USA

Christian Bermudez, MD, University of Pennsylvania, Philadelphia, PA, USA

Alexander Bernhardt, MD, University Heart Center Hamburg, Hamburg, Germany

Gerald Berry, MD, Stanford University, Stanford, CA, USA

Arvind Bhimaraj, MD, Houston Methodist Hospital, Houston, TX, USA

Edo Birati, MD, University of Pennsylvania, Philadelphia, PA, USA

Joshua Blatter, MD, Washington University School of Medicine, St. Louis, MO, USA

Nancy Blumenthal, CRNP, Hospital of the University of Pennsylvania, Philadelphia, PA, USA

Udo Boeken, MD, PhD, University Hospital Duesseldorf, Duesseldorf, Germany

Massimo Bonacchi, MD, University of Florence, Florence, Italy

Pramod Bonde, MD, Yale University School of Medicine, New Haven, CT, USA

Andrew Boyle, MD, Thomas Jefferson University, Philadelphia, PA, USA

Mary Bradbury, PharmD, Inova Fairfax Hospital, Falls Church, VA, USA

Meredith Brisco, MD, MSCE, Temple University, Philadelphia, PA, USA

Patrick Bruneval, MD, Hospital European Georges Pompidou, Paris, France

Marie Budev, DO, MPH, Cleveland Clinic, Cleveland, OH, USA

Fay Burrows, BPharm, St Vincent's Hospital, Sydney, Australia

Marco Caccamo, DO, Indiana University, Indianapolis, IN, USA

Barbara Cahill, MD, University of Utah, Salt Lake City, UT, USA

Charles Canver, MD, Duke Cardiovascular Surgery of Danville, Danville, VA, USA

Daniel Chambers, MBBS, MRCP, FRACP, MD, The Prince Charles Hospital, Brisbane, Australia

Patricia Chang, MD, University of North Carolina, Chapel Hill, NC, USA

Anshuman Chaturvedi, MD, FRCPath, Univ Hospital of South Manchester, Manchester, United Kingdom

Jonathan Chen, MD, Seattle Children's Hospital, Seattle, WA, USA

Leway Chen, MD, MPH, University of Rochester Medical Center, Rochester, NY, USA

Robert Chen, MD, MPH, Taipei Tzuchi Hospital, New Taipei City, Taiwan

Allen Cheng, MD, Jewish Hospital, University of Louisville, Louisville, KY, USA

Richard Cheng, MD, University of Washington, Seattle, WA, USA

Laveena Chhatwani, MD, Stanford University, Stanford, CA, USA

Young-Jae Cho, MD, MPH, Seoul National University Bundang Hospital, Seoul, Korea, Republic of

Dawn Christensen, MS, CRNP, MyLVAD, Pine Grove, PA, USA

Agnieszka Ciarka, MD, KU Leuven, Leuven, Belgium

Jose Cifrian, MD, Hospital Valdecilla, Santander, Spain

Tamara Claridge, PharmD, Hospital of the University of Pennsylvania, Philadelphia, PA, USA

Stephen Clark, FRCS, Freeman Hospital, Newcastle upon Tyne, United Kingdom

Brian Clarke, MD, University of Calgary, Calgary, AB, Canada

Adam Cochrane, PharmD, Inova Fairfax Hospital, Falls Church, VA, USA

Erin Coglianese, MD, Loyola University Medical Center, Maywood, IL, USA

Pamela Combs, PhD, RN, Jewish Hospital, Louisville, KY, USA

Mark Connellan, FRACS, St Vincent's Hospital, Sydney, Australia

Carol Conrad, MD, Stanford University, Stanford, CA, USA

Jennifer Conway, MD, Stollery Children's Hospital, Edmonton, AB, Canada

Hannah Copeland, MD, VA McGuire Medical Center/Virginia Commonwealth Univ, Richmond, VA, USA

Vlad Cotarlan, MD, University of Iowa, Iowa City, IA, USA

Melissa Cousino, PhD, University of Michigan, Ann Arbor, MI, USA

Jennifer Cowger, MD, MS, St Vincent Hospital, Indianapolis, IN, USA

Rachel Crackett, MSc, Freeman Hospital, Newcastle upon Tyne, United Kingdom

Lara Danziger-Isakov, MD, MPH, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA

Todd Dardas, MD, University of Washington, Seattle, WA, USA

Hiroshi Date, MD, Kyoto University, Kyoto, Japan

Teresa De Marco, MD, FACC, UCSF, San Francisco, CA, USA

Marc de Perrot, MD, Toronto General Hospital/UHN, Toronto, ON, Canada

Fabio de Robertis, MD, Harefield Hospital, Harefield, United Kingdom

Juan F. Delgado, PhD, University Hospital 12 de Octubre, Madrid, Spain

Göran Dellgren, MD, PhD, Sahlgrenska University Hospital, Goteborg, Sweden

Eugene DePasquale, MD, UCLA Medical Center, Los Angeles, CA, USA

Tobias Deuse, MD, PhD, UCSF, San Francisco, CA, USA

Joshua Diamond, MD, University of Pennsylvania, Philadelphia, PA, USA

Michael Dickinson, MD, Spectrum Health, Grand Rapids, MI, USA

Esme Dijke, PhD, University of Alberta, Edmonton, AB, Canada

Daniel Dilling, MD, Loyola University School of Medicine, Maywood, IL, USA

Anne Dipchand, MD, Hospital for Sick Children, Toronto, ON, Canada

Karen Doucette, MD, MSc, University of Alberta, Edmonton, AB, Canada

Mark Drazner, MD, UT Southwestern Medical Center, Dallas, TX, USA

Ignacio Echenique, MD, Cleveland Clinic Florida, Weston, FL, USA

Peter Eckman, MD, Minneapolis Heart Institute, Minneapolis, MN, USA

Sitaramesh Emani, MD, The Ohio State University, Columbus, OH, USA

Christopher Ensor, PharmD, BCPS-CV, University of Pittsburgh, Pittsburgh, PA, USA

Eric Epailly, MD, Les Hopitaux University, Strasbourg, France

Jennifer Eshelman, PharmD, Children's Hospital Colorado, Denver, CO, USA

Melanie Everitt, MD, Children's Hospital Colorado, Denver, CO, USA

Elie Fadel, MD, Hôpital Marie Lannenlongue, Le Plessis Robinson, France

Marny Fedrigo, MD, University of Padova, Padova, Italy

Brian Feingold, MD, MS, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA

David Feldman, MD, PhD, The Ohio State University, Columbus, OH, USA

Matthew Fenton, MRCPCH, Great Ormond Street Hospital, London, United Kingdom

Nowell Fine, MD, University of Calgary, Calgary, AB, Canada

Katrina Ford, BPharm, Great Ormond Street Hospital, London, United Kingdom

Laura Frye, MD, University of Chicago, Chicago, IL, USA

Louise Fuller, PT, Alfred Hospital, Melbourne, Australia

Maria Gazzaneo, MD, Baylor College of Medicine, Houston, TX, USA

Mahazarin Ginwalla, MD, University Hospitals Case Medical Center, Cleveland, OH, USA

Reda Girgis, MD, Spectrum Health Hospitals, Grand Rapids, MI, USA

Allan Glanville, MBBS, MD, FRACP, St. Vincent's Hospital, Sydney, Australia

Laurent Godinas, MD, CHU UCL Namur, Yvoir, Belgium

Hilary Goldberg, MD, Brigham and Women's Hospital, Boston, MA, USA

Daniel Goldstein, MD, Montefiore Medical Center, New York, NY, USA

Ranny Goldwasser, MD, University Children's Hospital, Heidelberg, Germany

José González, MD, Hospital Universitari de Bellvitge, Barcelona, Spain

Jens Gottlieb, MD, Hannover Medical School, Hannover, Germany

Kathleen Grady, PhD, APN, FAAN, Northwestern University, Chicago, IL, USA

Emily Granger, MBBS, FRAC, St. Vincent's Hospital, Sydney, Australia

Steven Greenway, MD, University of Calgary, Calgary, AB, Canada

Mark Greer, MB Bch, Hannover Medical School, Hannover, Germany

Aric Gregson, MD, UCLA, Los Angeles, CA, USA

Bartley Griffith, MD, University of Maryland, Baltimore, MD, USA

Jan Gummert, MD, PhD, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany

Dipankar Gupta, MBBS, DCH, MD, University of Florida, Gainesville, FL, USA

Ramsey Hachem, MD, Washington University School of Medicine, St. Louis, MO, USA

Shelley Hall, MD, Baylor University Medical Center, Dallas, TX, USA

Matthew Hartwig, MD, Duke University, Durham, NC, USA

Heather Henderson, MD, Duke University, Durham, NC, USA

Mark Hicks, PhD, St Vincent's Hospital, Sydney, Australia

Charles Hoopes, MD, University of Alabama, Birmingham, AL, USA

Peter Hopkins, FRACP, The Prince Charles Hospital, Brisbane, Australia

Ed Horn, PharmD, BCPS, Allegheny General Hospital, Pittsburgh, PA, USA

Eileen Hsich, MD, Cleveland Clinic, Cleveland, OH, USA

Manon Huibers, MSc, University Medical Center Utrecht, Utrecht, Netherlands

Teruhiko Imamura, MD, PhD, University of Tokyo, Tokyo, Japan

Hanine Inaty, MD, Cleveland Clinic Foundation, Columbus, OH, USA

Amanda Ingemi, PharmD, Sentara Norfolk General Hospital, Norfolk, VA, USA

Claire Irving, MBChB, MRCPCH, MD, Children's Hospital Westmead, Sydney, Australia

Michael Ison, MD, MS, Northwestern University, Chicago, IL, USA

Steve Ivulich, BPharm, St Vincent's Hospital, Sydney, Australia

Miriam Jacob, MD, Cleveland Clinic, Cleveland, OH, USA

George Javorsky, MBBS, FRACP, The Prince Charles Hospital, Brisbane, Australia

Susie Joseph, MD, Baylor University Medical Center, Dallas, TX, USA

David Joyce, MD, Mayo Clinic, Rochester, MN, USA

Sung-Ho Jung, MD, Asan Medical Center, Seoul, Korea, Republic of

Stephen Juvet, MD, PhD, FRCPC, Toronto General Hospital/UHN, Toronto, ON, Canada

Andrew Kao, MD, St Luke's Mid America Heart institute, Kansas City, MO, USA

Tomoko Kato, MD, PhD, Juntendo University School of Medicine, Tokyo, Japan

Jason Katz, MD, MHS, University of North Carolina, Chapel Hill, NC, USA

Mariska Kemna, MD, Seattle Children's Hospital, Seattle, WA, USA

Cassie Kennedy, MD, Mayo Clinic, Rochester, MN, USA

Feras Khaliel, MD, PhD, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

Ahmet Kilic, MD, The Ohio State University, Columbus, OH, USA

Kyung-Hee Kim, MD, PhD, Sejong General Hospital, Kyung-gi do, Korea, Republic of

Richard Kirk, FRCP, FRCPCH, UT Southwestern/Children's Medical Center, Dallas, TX, USA

Liviu Klein, MD, UCSF, San Francisco, CA, USA

Jon Kobashigawa, MD, Cedars-Sinai Heart Institute, Los Angeles, CA, USA

Robert Kormos, MD, FRCS(C), FAHA, University of Pittsburgh, Pittsburgh, PA, USA

Thomas Krabatsch, MD, PhD, German Heart Center, Berlin, Germany

Evan Kransdorf, MD, PhD, Cedars-Sinai Medical Center, Los Angeles, CA, USA

Thorsten Krueger, University Hospital Lausanne, Lausanne, Switzerland

Bartosz Kubisa, PhD, Pomeranian Medical University Szczecin, Szczecin, Poland

Christiane Kugler, PhD, Witten University, Dortmund, Germany

Chandra Kunavarapu, MD, Methodist Heart Failure & Transplant Program, San Antonio, TX, USA

Johanna Kwakkel van Erp, MD, PhD, University Medical Center Utrecht, Utrecht, Netherlands

Ashwin Lal, MD, Primary Children's Hospital, University of Utah, Salt Lake City, UT, USA

David Lanfear, MD, Henry Ford Hospital, Detroit, MI, USA

Sangjin Lee, MD, Spectrum Health, Grand Rapids, MI, USA

Roy Lee, PharmD, Stanford University, Stanford, CA, USA

Angeline Leet, MD, Alfred Hospital, Melbourne, Australia

Clive Lewis, MB BchirP, Papworth Hospital, Cambridge, United Kingdom

Christopher Lewis, MD, MB ChB, Auckland City Hospital, Auckland, New Zealand

Sern Lim, MD, University Hospital Birmingham NHS Trust, Birmingham, United Kingdom

Brian Lima, MD, CT and Vascular Surgeons, Dallas, TX, USA

Antonio Loforte, MD, PhD, S. Orsola-Malpighi Hospital, Bologna, Italy

Angela Lorts, MD, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA

Erin Lowery, MD, Loyola University Medical Center, Maywood, IL, USA

Lucian Lozonschi, MD, University of Wisconsin School of Medicine, Madison, WI, USA

Haifa Lyster, MSc, Royal Brompton and Harefield Hospital, Middlesex, United Kingdom

Jane MacIver, RN, NP, PhD, Toronto General Hospital/UHN, Toronto, ON, Canada

Monique Malouf, FRACP, St Vincent's Hospital, Sydney, Australia

Simon Maltais, MD, PhD, Mayo Clinic, Rochester, MN, USA

Donna Mancini, MD, Mount Sinai Medical Center, New York, NY, USA

Charles Marboe, MD, Columbia University, New York, NY, USA

Fabiana Marcondes-Braga, MD, PhD, Heart Institute, Sao Jose, Brazil

Marco Masetti, MD, PhD, University of Bologna, Bologna, Italy

Sofia Masri, MD, University of Washington, Seattle, WA, USA

David McGiffin, MBBS, FRACS, The Alfred Hospital, Melbourne, Australia

Tanya McWilliams, MD, PhD, Auckland City Hospital, Auckland, New Zealand

Ernestina Melicoff-Portillo, MD, Baylor College of Medicine, Houston, TX, USA

Anna Meyer, MD, Leipzig Heart Center, Leipzig, Germany

Sebastian Michel, MD, Cardiac Surgery, Ludwig Maximilian University, Munich, Germany

Rachel Miller, MD, Duke University Medical Center, Durham, NC, USA

Robert Miller, University of Calgary, Calgary, AB, Canada

Sonia Mirabet, MD, PhD, Hospital de Sant Pau, Barcelona, Spain

Nader Moazami, MD, Cleveland Clinic, Columbus, OH, USA

Nahush Mokadam, MD, University of Washington, Seattle, WA, USA

Ezequiel Molina, MD, MedStar Washington Hospital, Washington, DC, USA

Robert Morlend, MD, UT Southwestern Medical Center, Dallas, TX, USA

Matthew Morrell, MD, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

Catherine Murks, PhD, APN, University of Chicago, Chicago, IL, USA

Nandini Nair, MD, PhD, Texas Tech University Health Sciences Center, Lubbock, TX, USA

Johan Nilsson, MD, PhD, Skanes University Hospital, Lund, Sweden

Meinoshin Okumura, MD, Osaka University Graduate School of Medicine, Osaka, Japan

Minoru Ono, MD, PhD, The University of Tokyo Hospital, Tokyo, Japan

Mustafa Ozbaran, MD, Ege University School of Medicine, Izmir, Turkey

Robert Padera, MD, PhD, Brigham and Women's Hospital, Boston, MA, USA

Jay Pal, MD, PhD, University of Washington, Seattle, WA, USA

Maryse Palardy, MD, University of Michigan, Ann Arbor, MI, USA

Alessandro Palleschi, MD, Fondazione IRCCS Ca' Granda, Milano, Italy

Chetan Patel, MD, Duke University, Durham, NC, USA

Jignesh Patel, MD, PhD, Cedars-Sinai Heart Institute, Los Angeles, CA, USA

Michael Petty, PhD, RN, CNS, University of Minnesota, Minneapolis, MN, USA

Richard Pierson, MD, University of Maryland, Baltimore, MD, USA

Sean Pinney, MD, Mount Sinai Hospital, New York, NY, USA

Barbara Pisani, DO, Wake Forest Baptist Medical Center, Winston Salem, NC, USA

Evgenij Potapov, MD, PhD, German Heart Center, Berlin, Germany

Luciano Potena, MD, PhD, University of Bologna, Bologna, Italy

Ioana Preston, MD, Tufts Medical Center, Boston, MA, USA

Lynn Punnoose, MD, Temple University, Philadelphia, PA, USA

Amresh Raina, MD, Allegheny General Hospital, Pittsburgh, PA, USA

Navin Rajagopalan, MD, University of Kentucky, Lexington, KY, USA

Alexandra Rice, FRCPath, Harefield Hospital, Harefield, United Kingdom

Desiree Robson, RN, BSc (Hons), St Vincent's Hospital, Sydney, Australia

Anja Roden, MD, Mayo Clinic, Rochester, MN, USA

Joseph Rogers, MD, Duke University, Durham, NC, USA

Eulalia Roig, MD, Hospital Sant Pau, Barcelona, Spain

Sebastian Rojas, MD, Hannover Medical School, Hannover, Germany

Joseph Rossano, MD, The Children's Hospital of Philadelphia, Philadelphia, PA, USA

Victor Rossel, MD, Hospital Del Salvador, Santiago, Chile

Bart Rottier, MD, University Medical Center, Groningen, Netherlands

Stuart Russell, MD, Johns Hopkins Medical Center, Baltimore, MD, USA

Diyar Saeed, MD, PhD, Dusseldorf University Hospital, Dusseldorf, Germany

Christopher Salerno, MD, St Vincent Heart Center, Indianapolis, IN, USA

Nitasha Sarswat, MD, University of Chicago, Chicago, IL, USA

Janet Scheel, MD, Children's National Health System, Washington, DC, USA

Sarah Schettle, PA-C, Mayo Clinic, Rochester, MN, USA

Christof Schmid, MD, University Medical Center, Regensburg, Germany

Stephan Schueler, MD, PhD, FRCS, Freeman Hospital, Newcastle upon Tyne, United Kingdom

Sebastian Schulte Eistrup, MD, PhD, Schuechtermann Klinik, Bad Rothenfelde, Germany

Kurt Schumacher, MD, University of Michigan, Ann Arbor, MI, USA

Martin Schweiger, MD, Children's Hospital Zurich, Zurich, Switzerland

Nicolaus Schwerk, MD, Hannover Medical School, Hannover, Germany

Javier Segovia, MD, PhD, Hospital Puerta de Hierro, Madrid, Spain

Marc Semigran, MD, Massachusetts General Hospital, Boston, MA, USA

Ciara Shaver, MD, PhD, Vanderbilt University Medical Center, Nashville, TN, USA

Sara Shumway, MD, University of Minnesota, Minneapolis, MN, USA

Jorge Silva Enciso, MD, UCSD, San Diego, CA, USA

Jon Singer, MD, UCSF, San Francisco, CA, USA

Tajinder P. Singh, MD, MSc, Boston Children's Hospital, Boston, MA, USA

Frank Smart, MD, FACC, LSU School of Medicine, New Orleans, LA, USA

Patrick Smith, PhD, MPH, Duke University, Durham, NC, USA

Jacqueline Smits, MD, PhD, Eurotransplant International, Leiden, Netherlands

Melinda Solomon, MD, FRCPC, Hospital for Sick Children, Toronto, ON, Canada

Heike Spaderna, PhD, University of Trier, Trier, Germany

David Spielvogel, MD, Westchester Medical Center, Valhalla, NY, USA

James St. Louis, MD, Children's Mercy Hospital, Kansas City, MO, USA

William Stansfield, MD, University of Toronto, Toronto, ON, Canada

Josef Stehlik, MD, MPH, University of Utah, Salt Lake City, UT, USA

Garrick Stewart, MD, Brigham and Women's Hospital, Boston, MA, USA

Valentina Stosor, MD, Northwestern University, Chicago, IL, USA

Hiroo Takayama, MD, Columbia University, New York, NY, USA

Koji Takeda, MD, PhD, Columbia University, New York, NY, USA

Mitesh Thakrar, MD, University of Calgary, Calgary, AB, Canada

Sunu Thomas, MD, Massachusetts General Hospital, Boston, MA, USA

Josef Thul, MD, Children's Hospital, Giessen, Germany

Jamie Todd, MD, Duke University, Durham, NC, USA

Mustafa Toma, MD, St. Paul's Hospital, Vancouver, BC, Canada

Veli Topkara, MD, Columbia University, New York, NY, USA

Christopher Towe, MD, Cincinnati Children's Hospital, Cincinnati, OH, USA

Dirk Troitzsch, PhD, Aarhus University Hospital, Aarhus, Denmark

Patricia Uber, PharmD, Virginia Commonwealth University Health System, Richmond, VA, USA

Walt Uber, PharmD, Medical University of South Carolina, Charleston, SC, USA

Nir Uriel, MD, University of Chicago, Chicago, IL, USA

Simon Urschel, MD, University of Alberta, Edmonton, AB, Canada

Jean-Luc Vachiery, MD, CUB Hôpital Erasme, Brussels, Belgium

Vincent Valentine, MD, University of Alabama, Birmingham, AL, USA

Dirk Van Raemdonck, MD, PhD, University Hospitals Leuven, Leuven, Belgium

Bart Vanaudenaerde, PhD, KU Leuven, Leuven, Belgium

Rajamiyer Venkateswaran, FRCS, Wythenshawe Hospital, Manchester, United Kingdom

Geert Verleden, MD, PhD, University Hospital Leuven, Leuven, Belgium

Stijn Verleden, PhD, KU Leuven, Leuven, Belgium

Erik Verschuuren, MD, PhD, University Medical Center, Groningen, Netherlands

Himabindu Vidula, MD, University of Rochester, Rochester, NY, USA

Andre Vincentelli, MD, PhD, Centre Hospitalier Universitaire de Lille, Lille, France

Bojan Vrtovec, MD, PhD, UMC Ljubljana, Ljubljana, Slovenia

Mary Norine Walsh, MD, St Vincent Heart Center, Indianapolis, IN, USA

Andrae Wasler, MD, Medical University of Graz, Graz, Austria

Katharina Wassilew, MD, Dscmed, MHBA, Rigshospitalet, Copenhagen, Denmark

David Weill, MD, Stanford University, Palo Alto, CA, USA

Helen Whitford, MBBS, FRACP, Alfred Hospital, Melbourne, Australia

Bryan Whitson, MD, PhD, The Ohio State University, Columbus, OH, USA

Keith Wille, MD, MSPH, University of Alabama, Birmingham, AL, USA

Cameron Wolfe, MD, Duke University Medical Center, Durham, NC, USA

Tahir Yagdi, MD, Ege University, Izmir, Turkey

Stephanie Yerkovich, PhD, The Prince Charles Hospital, Brisbane, Australia

Daniel Yip, MD, Mayo Clinic, Rochester, MN, USA

Jong-Chan Youn, MD, PhD, Hallym University, Gyeonggido, Korea, Republic of

Melana Yuzefpolskaya, MD, Columbia University, New York, NY, USA

Steve Zangwill, MD, Phoenix Children's Hospital, Phoenix, AZ, USA

Chen Zhang, MD, PhD, Indiana University, Indianapolis, IN, USA

Tomasz Zielinski, MD, Institute of Cardiology, Warsaw, Poland

Andreas Zuckermann, MD, Medical University of Vienna, Vienna, Austria

# ISHLT COMMITTEE ROSTERS

## CORPORATE DEVELOPMENT COMMITTEE

Joseph Rogers, MD, Chair

Maryl R. Johnson, MD, ISHLT President

Andrew J. Fisher, FRCP, PhD, President-Elect

Amanda Rowe, ISHLT Executive Director

## EDUCATION COMMITTEE

Christopher H. Wigfield, MD, FRCS(C/TH), Director of Educational Affairs (2018)

Esme Dijke, PhD, Committee Vice Chair (2018)

Andrew J. Fisher, FRCP, PhD, Board of Directors Liaison (2019)

Amanda Rowe, ISHLT Executive Director

Additional Committee Members

David Baran, MD (2019)

Jennifer Cowger, MD, MS (2019)

Goran Dellgren, MD, PhD (2018)

Howard J. Eisen, MD (2017)

Mardi Gomberg-Maitland, MD, MSc (2017)

Donna M. Mancini, MD (2018)

Geert Verleden, MD, PhD (2019)

## GOVERNANCE COMMITTEE

Duane Davis, MD, MBA, Chair (2017)

Maryl R. Johnson, MD, ISHLT President (2018)

Andrew J. Fisher, FRCP, PhD, President-Elect (2019)

At Large Members

David O. Taylor, MD, Past President (2019)

Richard Kirk, FRCP, FRCPCH, Past Director (2017)

Stuart C. Sweet, MD, PhD, Past Secretary/Treasurer (2019)

## GRANTS AND AWARDS COMMITTEE

Stephan M. Ensminger, MD, DPhil, Co-Chair (2017)

Kathleen Grady, PhD, APN, FAAN, Co-Chair (2018)

Daniel Kreisel, MD, PhD, Co-Chair (2019)

Jason D. Christie, MD, Board of Directors Liaison

Lead Reviewers

Andrew E. Gelman, PhD

Mark S. Slaughter, MD

Laurie D. Snyder, MD

Dirk Van Raemdonck, MD, PhD

Louise M. Fuller, PT

Josef Stehlik, MD, MPH

## INTERNATIONAL AND INTER-SOCIETY COORDINATION COMMITTEE (I2C2)

Andreas Zuckermann, MD, Co-Chair (International) (2017)

Howard J. Eisen, MD, FAHA, FACC, FACP, Co-Chair (Inter-Societal) (2019)

Duane Davis, MD, MBA, Board of Directors Liaison

David O. Taylor, MD, Standards & Guidelines Committee Chair

Christopher H. Wigfield, MD, FRCS(C/Th), Director of Educational Affairs

Joseph Rogers, MD, Finance Committee Chair

Josef Stehlik, MD, MPH, Thoracic Registry Medical Director

Council Workforce Leaders

Bryan A. Whitson, MD, PhD, Basic Science & Translational Research Council (2017)

Daniel H. Kim, MD, Heart Failure & Transplantation Council (2018)

Martha L. Mooney, MD, Infectious Disease Council (2017)

Hirsch S. Mehta, Junior Faculty & Trainee Council (2019)

Sean Pinney, MD, Mechanical Circulatory Support Council (2017)

Rasha Adams, RN, Nursing, Health Sciences & Allied Health Council (2019)

Annalisa Angelini, MD, Pathology Council (2018)

James D. St. Louis, MD, Pediatric Thoracic Transplantation & Heart Failure Council (2018)

Douglas L. Jennings, PharmD, Pharmacy & Pharmacology Council (2018)

Manreet Kanwar, MD, Pulmonary Hypertension Council (2019)

Denis Hadjiliadis, MD, Pulmonary Transplantation Council (2017)

Ad Hoc Members

Jacob Lavee, MD (2017)

Lori J. West, MD, DPhil (2017)

Global Ambassadors

Alejandro Bertolotti, MD (Argentina) (2017)

Paolo Fernandes, MD, PhD (Brazil) (2017)

Douglas Greig, MD (Chile) (2017)

Adriana Torres Navas, MD (Colombia) (2017)

Karine Nubret, MD (France) (2017)

Denis Hadjiliadis, MD (Greece) (2017)

Sandeep G. Attawar, MD (India, New Delhi) (2017)

Yury Pya, MD (Kazakhstan) (2017)

Ashari Yunus, MD (Malaysia) (2017)

Amal A. Alotaibi, MD (Saudi Arabia) (2017)

Cumara C. Sivathasan, MBBS, FRCS (Singapore) (2017)

Ivan Knezevic, MD (Slovenia, Ljubljana) (2017)

Martin Schweiger, MD (Switzerland) (2017)

## ISHLT MECHANICALLY ASSISTED CIRCULATORY SUPPORT (IMACS®) REGISTRY STEERING COMMITTEE

James K. Kirklin, MD, Chair (2018)

Craig Collum, MPH, Administrator to Dr. Kirklin (2018)

Rongbing Xie, MPH, Statistician (2018)

Ryan Cantor, MSPH, Consulting Statistician (2018)

Jeffrey J. Teuteberg, MD, Board of Directors Liaison

Additional Members

Francisco Arabia, MD, USA (2017)

Theo DeBy, MBA, Germany (2018)

Anne I. Dipchand, MD, Canada (2017)

Daniel J. Goldstein, MD, USA (2018)

Margaret M. Hannan, MD, Ireland (2017)

Ulrich P. Jorde, MD, USA (2017)

Robert L. Kormos, MD, USA (2018)

Lars H. Lund, MD, PhD, Sweden (2017)

Mandeep Mehran, MD, MBBS, FACC, FACP, USA (2018)

Chris J. Merry, MD, Australia (2017)

Takeshi Nakatani, MD, PhD, Japan (2018)

Stephan Schueler, MD, PhD, FRCS, United Kingdom (2018)

Cumara C. Sivathasan, MBBS, FRCS, Singapore (2018)

Jose A. Tallaj, MD, USA (2020)

Maryl R. Johnson, MD, ISHLT President, Ex-Officio Member

Amanda Rowe, Executive Director, Ex-Officio Member

## INTERNATIONAL DCD REGISTRY STEERING COMMITTEE

Dirk Van Raemdonck, MD, PhD, Chair (2018)

Active Participating Centers (LUNG)

Allan R. Glanville, MBBS, MD, FRACP

Michael T. Musk, MBBS

Peter M. Hopkins, FRACP

Gregory I. Snell, MD

Marcelo Cypel, MD

Shaf Keshavjee, MD, FRCSC

Michiel E. Erasmus, MD, PhD

Marshall I. Hertz, MD

Roger D. Yusen, MD, MPH

Kenneth R. McCurry, MD, FACS

Frank D'Ovidio, MD, PhD

Starting Up Centers (Heart)

Stephen R. Large, FRCS

Steven SL Tsui, MD, FRCS

Kumud K. Dhital, MD, PhD

Peter MacDonald, MD, PhD

## INTERNATIONAL PEDIATRIC HEART FAILURE REGISTRY (IPHFR) STEERING COMMITTEE

Anne I. Dipchand, MD, Chair (2018)

Jeffrey J. Teuteberg, MD, Board of Directors Liaison

Christopher Almond, MD (2018)

Scott Auerbach, MD (2018)

Estela Azeka, MD (2018)

Wida S. Cherikh, PhD

Robert Gajarski, MD (2017)

Richard Kirk, FRCP, FRCPCH (2018)

Yuk Law, MD (2017)

Angela Lorts, MD (2018)

Elfriede Pahl, MD (2017)

Christina VanderPluym, MD (2018)

Warren Zuckerman, MD (2017)

## INTERNATIONAL THORACIC TRANSPLANT REGISTRY STEERING COMMITTEE

Josef Stehlik, MD, MPH, Medical Director & Chair (2017)

Daniel J. Goldstein, MD, Board of Directors Liaison (2018)

Associate Medical Directors

Lars H. Lund, Md, PhD, Adult Heart (Sept 2017)

Kiran K. Khush, MD, Adult Heart (Sept 2021)

Roger D. Yusen, MD, MPH, Adult Lung/Heart-Lung (Sept 2017)

Daniel C. Chambers, MBBS, MRCP, FRACP, MD, Adult Lung/Heart-Lung (Sept 2021)

Joseph W. Rossano, MD, Pediatric Heart (Sept 2019)

Samuel B. Goldfarb, MD, Pediatric Lung/Heart-Lung (Sept 2018)

Additional Members

Bronwyn J. Levvey, RN, Grad Dip Clin Ep, Outcomes (Sept 2018)

Bruno M. Meiser, MD, OEO Relations (Sept 2018)

Wida S. Cherikh, PhD, Biostatistics

Jaime Williamson, SAS Analyst

Anna Kucheryavaya, MD, Assistant Biostatistician

## JOURNAL OF HEART AND LUNG TRANSPLANTATION **(JHLT) EDITORIAL BOARD**

Mandeep R. Mehra, MD, MBBS, FACC, FACP, Editor-in-Chief

Patricia A. Uber, PharmD, Executive Editor

Maria Rosa Costanzo, MD, Consulting Editor (Editor Emeritus 1995-1999)

James K. Kirklin, MD, Consulting Editor (Editor Emeritus 2000-2009)

Hilary Campbell, Journal Office Coordinator

Editorial Board Consultants

Annalisa Angelini, MD (Italy)

Robert Aris, MD (USA)

William R. Auger, MD (USA)

David A. Baran, MD (USA)

Christian Benden, MD (Switzerland)

Christian A. Bermudez, MD (USA)

Marcelo Cantarovich, MD (Canada)

Charles E. Canter, MD (USA)

Pablo Castro, MD (Chile)

Jean M. Connors (USA)

Paul A. Corris, MB, FRCP (UK)

Kevin P. Daly, MD (USA)

John Dark, MB, FRCS (UK)

Kyle L. Dawson, PharmD, MBA, BCPS (USA)

Susan W. Denfield, MD (USA)

Mary Amanda Dew, PhD (USA)

Fabienne Dobbels, MSc, PhD (Belgium)

Thomas M. Egan, MD, MSC (USA)

Howard Eisen, MD (USA)

Roger W. Evans, PhD (USA)

Andrew J. Fisher, FRCP, PhD (UK)

Robert Frantz, MD (USA)

Allan R. Glanville, MBBS, MD, FRACP (Australia)

Daniel J. Goldstein, MD (USA)

Paolo Grossi, MD, PhD (Italy)

Margaret Hannan, MD (Ireland)

Marius M. Hoeper (Germany)

Peter M. Hopkins, FRACP (Australia)

Valluvan Jeevanandam, MD (USA)

Maryl R. Johnson, MD (USA)

Shaf Keshavjee, MD, FRCSC (Canada)

Kiran Kaur Khush, MD (USA)

Richard Kirk, FRCP, FRCPCH (USA)

Jon Kobashigawa, MD (USA)

Neal K. Lakdawala, MD (USA)

Lorriana Leard, MD (USA)

JoAnn Lindenfeld, MD (USA)

Peter MacDonald, MD, PhD (Australia)

Stanley I. Martin, MD (USA)

Tereza Martinu, MD (Canada)

Bruno Meiser, MD (Germany)

Thalachallour Mohanakumar, PhD (USA)

David Morales, MD (USA)

Ivan Netuka, MD, PhD (Czech Republic)

Jonah Odim, MD (USA)

Francis Pagani, MD, PhD (USA)

Myung H. Park, MD (USA)

Sean P. Pinney, MD (USA)

Jeffery L. Platt, MD (USA)

Evgenij V. Potapov, MD, PhD (Germany)

Luciano Potena, MD, PhD (Italy)

Joseph G. Rogers, MD (USA)

Heather J. Ross, MD, MHSc, FRCPC (Canada)

Lewis Rubin, MD (USA)

Stephan Schueler, MD, PhD, FRCS (UK)

Martin Schweiger, MD (Switzerland)

Keyur B. Shah, MD (USA)

Jacqueline M. Smits, MD, PhD (The Netherlands)

Josef Stehlik, MD, MPH (USA)

Jeffrey J. Teuteberg, MD (USA)

Jean Luc Vachiery, MD (Belgium)

Hector O. Ventura, MD (USA)

Geert Verleden, MD, PhD (Belgium)

Robin Vos, MD, PhD (Belgium)

Aaron Waxman, MD, PhD (USA)

Lori J. West, MD, DPhil (Canada)

Roger D. Yusen, MD, MPH (USA)

Michael Zakliczynski, MD (Poland)

## REGISTRIES AND DATABASES COMMITTEE

Josef Stehlik, MD, MPH, Chair (July 2017)

Jeffrey J. Teuteberg, MD, Board of Directors Liaison

Wida S. Cherikh, PhD, Biostatistician for the International Thoracic, International Pediatric Heart Failure, and Donation After Cardiac Death Registries

James K. Kirklin, MD, IMACS Registry Committee Chair (2018)

Rongbing Xie, MPH, IMACS Registry Biostatistician (2018)

Anne I. Dipchand, MD, International Pediatric Heart Failure Registry Committee Chair (2018)

Dirk Van Raemdonck, MD, PhD, International Donation after Cardiac Death (DCD) Registry Committee Chair

Roger D. Yusen, MD, MPH, Additional Member

## STANDARDS AND GUIDELINES COMMITTEE

David O. Taylor, MD, Chair (2019)

Maryl R. Johnson, MD, Past Chair & Board of Directors Liaison (2017)

Council Workforce Leaders

Keshava Rajagopal, MD, PhD, Basic Science & Translational Research Council (2018)

Hannah Copeland, MD, Heart Failure & Transplantation Council (2019)

Valentina Stosor, MD, Infectious Disease Council (2018)

Jose Nativi, MD, Junior Faculty & Trainee Council (2017)

David A. D'Alessandro, MD, Mechanical Circulatory Support Council (2018)

Annemarie Kaan, MCN, RN, Nursing, Health Sciences & Allied Health Council (2017)

Anja C. Roden, MD, Pathology Council (2019)

Steven Kindl, MD, Pediatric Thoracic Transplantation & Heart Failure Council (2019)

Kevin Daly, MD, Pediatric Thoracic Transplantation & Heart Failure Council (Non-voting mentee through 2017)

Robert L. Page, II, Pharm D, MS, Pharmacy & Pharmacology Council (2019)

Teresa De Marco, MD, FACC, Pulmonary Hypertension Council (2017)

Peter Hopkins, FRACP, Pulmonary Transplantation Council (2017)

## LINKS NEWSLETTER EDITORIAL STAFF

Vincent Valentine, MD, Editor

Megan Barrett, Managing Editor

Senior Associate Editors

Pamela Combs, PhD, RN

Paul Corris, MB, FRCP

John Dark, MB, FRCS

Roger Evans, PhD

Allan Glanville, MBBS, MD, FRACP

Maryl Johnson, MD

Associate Editors

Manreet Kanwar, MD, Cardiology

Claudius Mahr, DO, Cardiology

Joshua Mooney, MD, Junior Faculty & Trainee

Stephanie Pouch, MD, Infectious Disease

Emily Stimpson, MSN, FN, CCTC, Nursing, Health Sciences & Allied Health

Maryanne R. Chrisant, MD, Pediatrics

Daniel F. Dilling, MD, Pulmonary Transplantation

International Correspondents Board

Zargham Ahmadi, MD (Iran)

Javier Carbone, MD, PhD (Spain)

Marco Masetti, MD, PhD (Italy)

Andreas Zuckermann, MD (Austria)

Communications Liaisons

Howard J. Eisen, MD, Basic Science & Translational Research Council

David P. Nelson, MD, Heart Failure & Transplantation Council

Saima Aslam, MD, MS, Infectious Disease Council

Jorge Silva Enciso, MD, Junior Faculty & Trainee Council

Evgenij Potapov, MD, PhD, Mechanical Circulatory Support Council

Erin Wells, SBN, RN, CCTC, CPN, Nursing, Health Sciences & Allied Health Council

Brandon Larsen, MD, PhD, Pathology Council

Martin Schweiger, MD, Pediatric Thoracic Transplantation & Heart Failure Council

Ed Horn, PharmD, BCPS, Pharmacy & Pharmacology Council

Amresh Raina, MD, Pulmonary Hypertension Council

Jussi Tikkanen, MD, PhD, Pulmonary Transplantation Council

# ISHLT SCIENTIFIC COUNCIL OPERATING BOARDS

## BASIC SCIENCE AND TRANSLATIONAL RESEARCH

Sonja Schrepfer, MD, PhD, Chair

Edward Cantu, III, MD, Vice Chair

Joshua M. Diamond, MD, Vice Chair Elect

Kimberly L. Gandy, MD, PhD, Past Chair

Stephan M. Ensminger, MD, DPhil, Board of Directors Liaison

Mary Porteous, MD, Education Workforce Leader

Bryan A. Whitson, MD, PhD, I2C2 Workforce Leader

Keshava Rajagopal, MD, PhD, Standards & Guidelines Committee Workforce Leader

Doris A. Taylor, PhD, Senior Advisor

Jeffrey L. Platt, MD, Senior Advisor

Howard J. Eisen, MD, FAHA, FACC, FACP, ISHLT Links Newsletter Liaison

Pradeep P. A. Mammen, MD, FACC, FAHA, Heart Failure & Transplantation Council Liaison

Orla Morrissey, MD, Infectious Diseases Council Liaison

Simon Pecha, MD, Junior Faculty & Trainee Council Liaison

J. Michael DiMaio, MD, Mechanical Circulatory Support Council Liaison

Monica Horn, RN, CCRN, CCTC, Nursing, Health Sciences & Allied Health Council Liaison

Annalisa Angelini, MD, Pathology Council Liaison

Carol K. Conrad, MD, Pediatric Thoracic Transplantation & Heart Failure Council Liaison

Tam Khuu, PharmD, BCPS, Pharmacy & Pharmacology Council Liaison

Aaron B. Waxman, MD, PhD, Pulmonary Hypertension Council Liaison

Joshua M. Diamond, MD, Pulmonary Transplantation Council Liaison

## CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION

William R. Auger, MD, Chair

## HEART FAILURE AND TRANSPLANTATION

Michael Pham, MD, MPH, Chair

Jignesh K. Patel, MD, PhD, Vice Chair

Monica M. Colvin, MD, Past Chair

Howard J. Eisen, MD, FAHA, FACC, FACP, Board of Directors Liaison

Bojan Vrtovec, MD, PhD, Education Workforce Leader

Daniel H. Kim, MD, I2C2 Workforce Leader

Hannah Copeland, MD, Standards & Guidelines Committee Workforce Leader

David P. Nelson, MD, ISHLT Links Newsletter Liaison

Pradeep P.A. Mammen, MD, FACC, FAHA, Basic Science & Translational Research Council Liaison

Marco Masetti, MD, PhD, Junior Faculty & Trainee Council Liaison

Quincy Young, PhD, RPsych, Nursing, Health Sciences & Allied Health Council Liaison

## INFECTIOUS DISEASES

Paolo A. Grossi, MD, PhD, Chair

Stanley I. Martin, MD, Vice Chair

Me-Linh Luong, MD, Vice Chair Elect

Fernanda Silveira, MD, Past Chair

Lara Danziger-Isakov, MD, MPH, Board of Directors Liaison

Me-Linh Luong, MD, Education Workforce Leader

Martha Mooney, MD, I2C2 Workforce Leader

Valentina Stosor, MD, Standards & Guidelines Committee Workforce Leader

Saima Aslam, MD, MS, ISHLT Links Newsletter Liaison

Catherine Orla Morrissey, MD, Basic Science & Translational Research Council Liaison

Ignacio A. Echenique, MD, Junior Faculty & Trainee Council Liaison

## JUNIOR FACULTY AND TRAINEE

Keyur B. Shah, MD, Chair

Evan P. Kransdorf, MD, PhD, Vice Chair

Eugene C. DePasquale, MD, Past Chair

Duane Davis, MD, MBA, Board of Directors Liaison

Martin Schweiger, MD, Education Workforce Leader

Hirsch S. Mehta, MD, I2C2 Workforce Leader

Steven Kindel, MD, Standards & Guidelines Committee Workforce Leader

Jose Nativi, MD, Standards & Guidelines Committee Workforce Leader

Jorge Silva Enciso, MD, ISHLT Links Newsletter Liaison

Simon Pecha, MD, Basic Science & Translational Research Council Liaison

Marco Masetti, MD, PhD, Heart Failure & Transplantation Council Liaison

Ignacio Echenique, MD, Infectious Diseases Council Liaison

Feras Khaliel, MD, PhD, Mechanical Circulatory Support Council Liaison

Colleen K. McIlvennan, Nursing, Health Sciences & Allied Health Council Liaison

Claire A. Irving, MBChB, MRCPCH, MD, Pediatric Thoracic Transplantation & Heart Failure Council Liaison

Marco A. Caccamo, MD, Pulmonary Hypertension Council Liaison

Joshua J. Mooney, MD, Pulmonary Transplantation Council Liaison

## MECHANICAL CIRCULATORY SUPPORT

Stephan Schueler, MD, PhD, FRCS, Chair

Nir Uriel, MD, Vice Chair

Simon Maltais, MD, PhD, Vice Chair Elect

Ulrich P. Jorde, MD, Past Chair

Joseph Rogers, MD, Board of Directors Liaison

Diyar Saeed, MD, PhD, Education Workforce Leader

Sean P. Pinney, MD, I2C2 Workforce Leader

David A. D'Alessandro, MD, Standards & Guidelines Committee Workforce Leader

Evgenij V. Potapov, MD, ISHLT Links Newsletter Liaison

Dawn M. Christensen, MS, CRNP, VAD Coordinator Liaison

J. Michael DiMaio, MD, Basic Science & Translational Research Council Liaison

Feras Khaliel, MD, PhD, Junior Faculty & Trainee Council Liaison

Jennifer A. Beckman, MSN-FNP, RN, CHFN, Nursing, Health Sciences & Allied Health Council Liaison

Angela Lorts, MD, Pediatric Thoracic Transplantation & Heart Failure Council Liaison

## NURSING, HEALTH SCIENCES AND ALLIED HEALTH

Kevin Carney, MSN, CRNP, CCTC, Chair

Pamela S. Combs, PhD, RN, Vice Chair

Samantha J. Anthony, PhD, MSW, Past Chair

Michael G. Petty, PhD, RN, CCNS, CNS, Board of Directors Liaison

Caron Burch, RN, MSN, FNP, CCTC, Education Workforce Leader

Rasha Adam, RN, I2C2 Workforce Leader

Annemarie Kaan, MCN, RN, Standards & Guidelines Committee Workforce Leader

Louise M. Fuller, PT, Grants & Award Committee Workforce Leader

Erin Wells, RN, ISHLT Links Newsletter Liaison

Monica Horn, RN, CCRN, CCTC, Basic Science & Translational Research Council Liaison

Quincy Young, PhD, RPsych, Heart Failure & Transplantation Council Liaison

Jennifer A. Beckman, MSN-FNP, RN, CHFN, Mechanical Circulatory Support Council Liaison

Rachel M. Crackett, MSc, Pulmonary Hypertension Council Liaison

Tara Fuller, RN, MSN, CCRN, CCTN, Pulmonary Transplantation Council Liaison

## PATHOLOGY

Martin J. Goddard, FRCS, MRCPa, Chair

Robert F. Padera, MD, PhD, Vice Chair

Fiorella Calabrese, MD, Vice Chair Elect

Carmela D. Tan, MD, Past Chair

Dirk Van Raemdonck, MD, PhD, Board of Directors Liaison

Carol F. Farver, MD, Education Workforce Leader

Annalisa Angelini, MD, I2C2 Workforce Leader and Basic Science & Translational Research Council Liaison

Anja C. Roden, MD, Standards & Guidelines Committee Workforce Leader

Brandon T. Larsen, MD, PhD, ISHLT Links Newsletter Liaison

## PEDIATRIC THORACIC TRANSPLANTATION AND HEART FAILURE

Tajinder P. Singh, MD, MSc, Chair

Brian Feingold, MD, MS, Vice Chair

Carol K. Conrad, MD, Vice Chair Elect

Janet N. Scheel, MD, Past Chair

Christian Benden, MD, Board of Directors Liaison

Debra A. Dodd, MD, Education Workforce Leader

James D. St. Louis, MD, I2C2 Workforce Leader

Steven Kindel, MD, Standards & Guidelines Committee Workforce Leader

Kevin Daly, MD, Standards & Guidelines Committee Workforce Leader

Ryan Butts, MD, Pediatric Heart Failure Workforce Leader

Martin Schweiger, MD, ISHLT Links Newsletter Liaison

Carol K. Conrad, MD, Basic Science & Translational Research Council Liaison

Claire Irving, MBChB, MRCPCH, Junior Faculty & Trainee Council Liaison

Angela Lorts, MD, Mechanical Circulatory Support Council Liaison

Erin Wells, RN, Nursing, Health Sciences & Allied Health Council Liaison

## PHARMACY AND PHARMACOLOGY

Walter Uber, PharmD, Chair

Adam B. Cochrane, PharmD, Vice Chair

Haifa Lyster, MSc, Vice Chair Elect

Tamara E. Claridge, PharmD, Past Chair

Tobias Deuse, MD, PhD, Board of Directors Liaison

Kyle L. Dawson, PharmD, Education Workforce Leader

Douglas L. Jennings, PharmD, I2C2 Workforce Leader

Robert L. Page, II, PharmD, MS, Standards & Guidelines Committee Workforce Leader

Edward Horn, PharmD, BCPS, ISHLT Links Newsletter Liaison

Tam Khuu, PharmD, BCPS, Basic Science & Translational Research Council Liaison

## PULMONARY HYPERTENSION

Dana P. McGlothlin, MD, Chair

Jean-Luc Vachiery, MD, Vice Chair

Mardi Gomberg-Maitland, MD, MSc, Past Chair

Andrew J. Fisher, FRCP, PhD, Board of Directors Liaison

Ioana R. Preston, MD, Education Workforce Leader

Oksana A. Shlobin, MD, I2C2 Workforce Leader

Teresa De Marco, MD, FACC, Standards & Guidelines Committee Workforce Leader

Amresh Raina, MD, ISHLT Links Newsletter Liaison

Aaron B. Waxman, MD, PhD, Basic Science & Translational Research Council Liaison

Marco A. Caccamo, MD, Junior Faculty & Trainee Council Liaison

Rachel M. Crackett, MSc, Nursing, Health Sciences & Allied Health Council Liaison

## PULMONARY TRANSPLANTATION

Cynthia J. Gries, MD, MSc, Chair

Ramsey R. Hachem, MD, Vice Chair

Michael Mulligan, MD, Past Chair

Peter M. Hopkins, FRACP, Board of Directors Liaison and Standards & Guidelines Committee Workforce Leader

Lorriana E. Leard, MD, Education Workforce Leader

Denis Hadjiliadis, MD, I2C2 Workforce Leader

Jonathan P. Singer, MD, MS, Quality of Life Workforce Leader

Jussi Tikkanen, MD, PhD, ISHLT Links Newsletter Liaison

Joshua Diamond, MD, Basic Science & Translational Research Council Liaison

Joshua J. Mooney, MD, Junior Faculty & Trainee Council Liaison

Tara R. Fuller, Nursing, Health Sciences & Allied Health Council Liaison

# PAST PRESIDENTS

1981-1982  | Michael Hess, MD

---|---

1982-1984  | Jack Copeland, MD

1984-1986  | Terence English, KBE, FRCS

1986-1988  | Stuart Jamieson, MD, FRCS

1988-1990  | Bruno Reichart, MD

1990-1991  | Margaret Billingham, MD

1991-1992  | Christian Cabrol, MD

1992-1993  | John O'Connell, MD

1993-1994  | Eric Rose, MD

1994-1995  | John Wallwork, FRCS

1995-1996  | Sharon Hunt, MD

1996-1997  | William Baumgartner, MD

1997-1998  | Leslie Miller, MD

1998-1999  | Alan Menkis, MD, FRCS(C)

1999-2000  | Robert L. Kormos, MD, FRCS(C), FAHA

2000-2001  | Anne Keogh, MBBS, MD

2001-2002  | James B. Young, MD

2002-2003  | Stephan Schueler, MD, PhD, FRCS

2003-2004  | Jon Kobashigawa, MD

2004-2005  | Alec Patterson, MD

2005-2006  | Mark L. Barr, MD

2006-2007  | Robert C. Robbins, MD

2007-2008  | Paul A. Corris, MB FRCP

2008-2009  | Mandeep R. Mehra, MD, MBBS, FACC, FACP

2009-2010  | James K. Kirklin, MD

2010-2011  | John Dark, MB, FRCS

2011-2012  | Lori J. West, MD, DPhil

2012-2013  | David O. Taylor, MD

2013-2014 | Allan R. Glanville, MBBS, MD, FRACP

2014-2015 | Hermann Reichenspurner, MD, PhD

2015-2016 | Duane Davis, MD, MBA

# PAST PROGRAM CHAIRS

1981  | San Francisco, CA | Edward B. Stinson, MD and Michael L. Hess, MD

---|---|---

1982  | Phoenix, AZ | Michael Kaye and Bernard Gersh

1983  | New Orleans, LA | Stuart W. Jamieson, MD and Mark E. Thompson, MD

1984  | New York, NY | Randall B. Griepp, MD

1985  | Anaheim, CA | Terence A. H. English and Hillel Laks

1986  | New York, NY | Terence A. H. English

1987  | New Orleans, LA | John C. Baldwin, MD

1988  | Los Angeles, CA | John C. Baldwin, MD

1989  | Munich, Germany | Bruno Reichart, MD

1990  | San Diego, CA | D. Glenn Pennington, MD

1991  | Paris, France | John B. O'Connell, MD

1992  | San Diego, CA | Eric A. Rose, MD

1993  | Boca Raton, FL | Maria Rosa Costanzo, MD

1994  | Venice, Italy | John Wallwork, MBChB, FRCS

1995  | San Francisco, CA | Leslie W. Miller, MD

1996  | New York, NY | William A. Baumgartner, MD

1997  | London, England | Stephan Schueler, MD

1998  | Chicago, IL | James B. Young, MD

1999  | San Francisco, CA | Mark L. Barr, MD

2000  | Osaka, Japan | Jon Kobashigawa, MD

2001  | Vancouver, Canada | David O. Taylor, MD

2002  | Washington, DC | Robert C. Robbins, MD

2003  | Vienna, Austria | Bruce R. Rosengard, MD

2004  | San Francisco, CA | Mandeep R. Mehra, MD

2005  | Philadelphia, PA | Shaf Keshavjee, MD

2006  | Madrid, Spain | John Dark, MB, FRCS

2007  | San Francisco, CA | Duane Davis, MD

2008  | Boston, MA | Lori J. West, MD, DPhil

2009  | Paris, France | Randall C. Starling, MD, MPH

2010  | Chicago, IL | Hermann Reichenspurner, MD, PhD

2011  | San Diego, CA | Richard N. Pierson, III, MD

2012  | Prague, Czech Republic | Stuart C. Sweet, MD, PhD

2013  | Montreal, Canada | Allan R. Glanville, MBBS, MD, FRACP

2014 | San Diego, CA | Jason D. Christie, MD

2015 | Nice, France | Andreas Zuckermann, MD

2016 | Washington, DC | Andrew J. Fisher, FRCP, PhD

# JOURNAL AND LINKS NEWSLETTER EDITORS

JOURNAL OF HEART AND LUNG TRANSPLANTATION

1981-1985 | Jacques G. Losman, MD

---|---

1986-1994 | Michael P. Kaye, MD

1995-1999 | Maria Rosa Costanzo, MD

2000-2009 | James K. Kirklin, MD

2010-Present | Mandeep R. Mehra, MD

LINKS NEWSLETTER

2008-2011 | David S. Feldman, MD, PhD

---|---

2011-Present | Vincent G. Valentine, MD

# REGISTRY MEDICAL DIRECTORS

INTERNATIONAL REGISTRY FOR HEART AND LUNG TRANSPLANTATION

1987-1993 | Michael P. Kaye, MD

---|---

1993-2001 | Jeffrey D. Hosenpud, MD

2001-2012 | Marshall I. Hertz, MD

2012-Present | Josef Stehlik, MD, PhD

# ISHLT AWARD RECIPIENTS

# OUTSTANDING ACHIEVEMENT AWARDS:

## ISHLT PIONEER AWARD

2000  | Christiaan Barnard, MD

---|---

|

Joel D. Cooper, MD

|

Norman E. Shumway, MD

2002  | Michael DeBakey, MD

|

Bruce A. Reitz, MD

2006  | Leonard L. Bailey, MD

2008  | Richard E. Lower, MD

2009  | Christian E. A. Cabrol, MD

2011  | Elizabeth Hammond, MD

2013  | Jack G. Copeland, MD

2015 | Bruno Reichart, MD

2016 | Sir Roy Calne, FRCP, FRCS, FRS

## ISHLT LIFETIME ACHIEVEMENT AWARD

1996  | Norman Shumway, MD

---|---

1999  | Keith Reemtsma, MD

2004  | Sir Magdi Yacoub, MD

2010  | Margaret Billingham, MD

2012  | Sharon Hunt, MD

2014 | Sir Terence English, KBE, FRCS

2016 | Adrian Kantrowitz, MD

|

Jean Kantrowitz, MPH

## ISHLT LIFETIME SERVICE AWARD

1996  | Michael P. Kaye, MD

---|---

1997  | Jacques G. Losman, MD

## EMERITUS MEMBERSHIP

Margaret D. Allen, MD

---

Christian Cabrol, MD

Sir Terence English, KBE, FRCS

Albert J. Guerraty, MD

Sharon A. Hunt, MD

Carl V. Leier, MD

Bruno Reichart, MD

Marlene Rose, PhD

John Wallwork, FRCS

Elaine M. Winkel, MD

Prof. Magdi Yacoub, MD

# GRANTS AND SCHOLARSHIPS:

## ISHLT NORMAN E. SHUMWAY CAREER DEVELOPMENT AWARD

2000  | Gordon D. Wu, MD (supported by Roche)

---|---

2002  | Anthony Azakie, MD (supported by Roche)

2004  | Allan M. Ramirez, MD (supported by Novartis Pharma)

2006  | Dennis W. Wigle, MD, PhD (supported by Astellas Pharma)

2008  | Glen Westall, MD, PhD (supported by Roche)

2010  | Sonja Schrepfer, MD, PhD (supported by Astellas)

2012  | Tereza Martinu, MD, PhD

2014 | Keshava Rajagopal, MD, PhD

2015 | Xingan Wang, MD, PhD

2016 | Stephen Juvet, MD, PhD, FRCPC

2017 | Nicole Valenzuela, PhD, D(ABHI) (supported by a gift from Enduring Hearts)

## ISHLT JOEL D. COOPER CAREER DEVELOPMENT AWARD

2017 | Keki Blasara, MD

---|---

## ISHLT NURSING RESEARCH GRANT AWARD

1997  | Eileen Collins, RN, PhD

---|---

1998  | Katherine St. Clair, RN, MSN

1999  | Jeanne Salyer, PhD

2000  | Nancy M. Albert, MSN, RN

2001  | Lynn Doering, RN, DNSc

2002  | Annette J. De Vito Dabbs, RN, MN, PhD

2003  | Diane H. Leloudis, RN, MSN

|

Janet E. Madill, PhD

2004  | Deidre E. Logan, PhD

2005  | Annemarie F. Kaan, MCN

2006  | Thierry Troosters, PhD

2007  | Mi-Kyung Song, PhD

2008  | Stacey M. Pollock-BarZiv, PhD

2009  | Jane MacIver, RN, MSc

2010  | Heike Spaderna, PhD

|

Gerdi Weidner, PhD

2011  | Christiane Kugler, PhD (supported by CSL Behring)

|

Hilde Bollen, RN

2012  | Lut Berben, PhD, RN (supported by CSL Behring)

|

Connie White-Williams, PhD, RN, FAAN

2013  | Jo Wray, PhD

|

Jane Haines, DNP, RN, CMSRN

2014 | Lea Ann Matura, PhD, RN

2015 | JiYeon Choi, PhD, RN

2016 | Mohammad Alrawashdeh, BSN, MSN

2016 | Melissa Cousino, PhD (Jointly Funded by Enduring Hearts)

2017 | Samantha Anthony, PhD, MSW

## ISHLT RESEARCH FELLOWSHIP AWARD

1995  | Frances L. Johnson, MD (supported by Ortho-Biotech)

---|---

1996  | Tuija S. Ikonen, MD (supported by Roche)

|

Andrew F. Pierre, MD (supported by Ortho-Biotech)

1997  | Jonathan Chen, MD (supported by Roche)

|

Alyssa M. Krasinskas, MD (supported by Astellas)

|

Owen T. Lawrence, MD (supported by Ortho-Biotech)

|

Anne K. Raisanen-Sokolowski, MD (supported by Roche)

1998  | Kelly S.A. Blair, MD (supported by Roche)

|

A.M. El Gamel, MD (supported by Roche)

|

Christine L. Lau, MD (supported by Wyeth-Ayerst)

|

Scott D. Ross, MD

|

Margaret L. Schwarze, MD (supported by Novartis)

1999  | George Juang, MD (supported by Novartis)

|

Sivasai Krovvidi, PhD (supported by Roche)

|

Satoshi Saito, MD (supported by Novartis)

|

Donald Wong, PhD (supported by Roche)

2000  | Richard S. Lee, MD (supported by Novartis)

|

Christopher H. Wigfield, FRCS (supported by Roche)

2001  | Arnar Geirsson, MD (supported by Roche)

|

Matteo Vatta, PhD (supported by Roche)

2002  | Ruediger Hoebelt, MD (supported by Roche)

2003  | Ewout J. van den Bos, MD (supported by Astellas)

|

Felix Fernandez, MD (supported by Roche)

2004  | Christian A. Gleissner, MD (supported by Astellas)

|

Tsuyoshi Shoji, MD, PhD (supported by Actelion)

|

Kendra N. Taylor, PhD (supported by Roche)

|

Monica Zwierzchonieuska, MD (supported by XDx)

2005  | Ryan C. Fields, MD (supported by Chiron)

|

Arne Neyrinck, MD (supported by Astellas)

|

Ahmad Saad, MD (supported by Roche)

2006  | Rachel L. Anderson, MBBS (supported by Roche)

|

Zhaohui Li, PhD (supported by Transmedics)

|

Heather E. Merry, MD (supported by Encysive)

|

Edward N. Seung, PhD (supported by XDx)

|

Matthew J. Weiss, MD (supported by Novartis)

2007  | J. Raymond Fitzpatrick, III, MD (supported by Encysive)

|

Howard J. Huang, MD (supported by Transmedics)

|

Mylvganam Jeyakanthan, MD (supported by XDx)

|

Timothy M. Millington, MD (supported by Novartis)

|

Satish N. Nadig, MD (supported by Roche)

|

Takeshi Oyaizu, MD, PhD (supported by Actelion)

|

Sonja Schrepfer, MD (supported by Astellas)

2008 | Jonathan Choy, PhD (supported by XDx)

|

Satoshi Itoh, MD (supported by Transmedics)

|

Tereza Martinu, MD (supported by Novartis)

|

Deepti Saini, PhD (supported by Gilead)

|

Atsushi Shiozaki, MD, PhD (supported by Astellas)

|

Seiichiro Sugimoto, MD, PhD (supported by Roche)

2009  | Hua Shen, MD, PhD (supported by Astellas)

|

Tobias Deuse, MD, PhD (supported by Novartis)

|

Masahiro Miyajima, MD, PhD (supported by XDx)

|

Shin Hirayama, MD, PhD (supported by Gilead)

2010  | Esme Dijke, PhD (supported by Novartis)

|

Smita Sihag, MD (supported by Genentech)

|

Sumiharu Yamamoto, MD (supported by Gilead)

|

Khurram Shahzad, MD (supported by United Therapeutics)

|

Nina Pilat, MSc, PhD (supported by XDx)

2011  | Alejandro Bribriesco, MD (supported by Astellas)

|

Alexey Dashkevich, MD (supported by XDx)

|

Patricia E. de Almeida, DVM, MS, PhD

|

Tiago Machuca, MD, PhD

2012  | Stephen C. Juvet, MD, FRCPC

|

Maria Lucia L. Madariga, MD

|

Jessica H. Spahn, PhD

|

Konstantinos Malliaras, PhD

2013  | Nikolaos Diakos, MD

|

Raymond Givens, MD, PhD

|

Pablo Sanchez, MD, PhD

2014 | Charles Evans, MD

|

Christine Lin, MD

|

Stijn Verleden, PhD

2015 | Jonathan Merola, MD

2016 | Hsi-Min Hsaio, PhD

|

Nikolas Skartsis, MD, PhD

|

Corey Tabit, MD, MBA, MPH

2017 | Ramiro Fernandez, MD

|

Jane O, MD (joint award with Enduring Hearts)

## ISHLT TRANSPLANT REGISTRY EARLY CAREER AWARD

(formerly Junior Faculty Award)

2007  | Beth D. Kaufman, MD

---|---

2008  | Cynthia Gries, MD, MSc

|

Scott Halpern, MD, PhD

|

Josef Stehlik, MD, MPH

2010  | Jennifer Conway, MD, FRCPC

|

Kiran K. Khush, MD, MAS

2011  | Jose Nativi, MD

2012  | Erin M. Lowery, MD

|

Omar E. Wever-Pinzon, MD

2013  | Chesney Castleberry, MD

|

Eugene DePasquale, MD

|

Aaron Healy, MD

2014 | Marian Urban, MD

|

Miranda Paraskeva, MBBS

|

Hrishikesh Kulkarni, MD

|

Agnieszka Ciarka, MD, PhD

2015 | Livia Goldraich, MD, MSc

|

Deipanjan Nandi, MD, MSc

|

Evan Kransdorf, MD, PhD

|

Manreet Kanwar, MD

|

Natasha Loghmanpour, PhD

|

Alexander Bernhardt, MD

|

Jong-Chan Youn, MD, PhD

2016 | Sai Bhagra, MBBS, MRCP

|

Forum Kamdar, MD

|

Marco Masetti, MD, PhD

|

Joshua Mooney, MD

|

Edit Nagy, MD, PhD

2017 | Laith Alshawabkeh, MD, MSc

|

Yuka Furuya, MD

|

Christian Heim, MD

|

Monique Robinson, MBBS, MRCP, DPhil

|

Lorenzo Zaffiri, MD, PhD

## ISHLT/BAYER PULMONARY HYPERTENSION RESEARCH GRANT AWARD

2014 | Benjamin Freed, MD

---|---

## ISHLT/O.H. FRAZIER AWARD IN MCS TRANSLATIONAL RESEARCH Sponsored by Medtronic (formerly ISHLT/O.H. FRAZIER AWARD IN MCS TRANSLATIONAL RESEARCH Sponsored by HeartWare and ISHLT/HeartWare Award for Translational Research in MCS)

2014 | Leigh Reardon, MD

---|---

2015 | Alexander Bernhardt, MD

2016 | Todd Dardas, MD, MS

2017 | Yasuhiro Shudo, MD, PhD

## ISHLT Branislav Radovancevic Memorial Fellowship Grant (supported by Thoratec)

2009 | Sasa D. Borovic, MD

---|---

2010 | Iki Adachi, MD

2012 | Antigone Koliopoulou, MD

2014 | Masahiro Ono, MD, PhD

## ISHLT INTERNATIONAL TRAVELING SCHOLARSHIP AWARD

2011  | Stephanie T. Yerkovich, PhD

---|---

|

Sarah E. Gilpin, PhD

|

Kimberly M. Derkatz, BNSc

|

Jennifer Conway, MD, FRCPC

2012  | Ramin E. Beygui, MD

|

Kevin C. Carney, MSN

|

Alexandre Souza Cauduro, MD

|

Esme Dijke, PhD

|

Ana Belen Mendez, MD

|

David Schibilsky, MD

|

Aleem Siddique, MBBS

|

Amparo Solé, MD, PhD

|

Manon Huibers, MSc

|

Daniel R. Goldstein, MD

|

Laveena Munshi, MD, FRCPC

|

Marco Masetti, MD

|

Rochelle M. Gellatly, PScPharm, ACPR, PharmD

2013  | Alison Gareau, MSc

|

Erin Schumer, MD, MS

|

Bojan Vrtovec, MD, PhD

|

Marsha Renikunta, PhD (student)

|

Katie Morley, BA(Hons), RCN, MA

|

Ali Yeginsu, MD

|

Fabrizio Gandolfo, MD

|

Marian Urban, MD

|

Alexander Bernhardt, MD

|

Victor Rossel, MD

|

Mohammed Quader, MD

2014 | Marny Fedrigo, MD, PhD

|

Zachary Kon, MD

|

Evgenios Neofytou, MD

|

Dong, Wang, MD

|

Stephen Clark, DM, FRCS

|

Caroline Patterson, BMBS, BMedSci, MRCP

|

Tahaunty Pena, MD

2015 | Oisin O'Connell, MD, MRCPI

|

Lucas Van Aelst, MD, PhD

|

Arezu Aliabadi, MD

|

Timothy Sladden, MBBS, BVSc

|

Bao Tran, MD

|

L G Saptharishi, MD, DM

|

Allison Carroll, MD

|

Akshay Pendyal, MD

|

Stefania Paolillo, MD, PhD

|

Soumitra Sinha Roy, MD

2016 | Lucas Van Aelst, MD, PhD

|

Espeed Khoshin, MB ChB, MD, FRCS

## ISHLT LEACH-ABRAMSON-IMHOFF LINKS TRAVEL AWARDS

2012  | Tereza Martinu, MD, Writer of the Year

---|---

|

Stanley I. Martin, MD, First Runner-Up

|

Luciano Potena, MD, PhD, First Runner-Up

|

Nancy P. Blumenthal, CRNP, Honorable Mention

|

Bronwyn J. Levvey, RN, Honorable Mention

|

Javier Carbone, MD, PhD, Honorable Mention

|

Stavros G. Drakos, MD, Honorable Mention

|

Daniel F. Dilling, MD, Honorable Mention

2013  | Michele Estabrook, MD, Writer of the Year

|

Melanie Everitt, MD, First Runner-Up

|

Christina Migliore, MD, First Runner-Up

|

Veronica Franco, MD, Honorable Mention

|

Manreet Kanwar, MD, Honorable Mention

|

Luciano Potena, MD, PhD, Honorable Mention

|

Macé Schuurmans, MD, Honorable Mention

|

Jeffrey J. Teuteberg, MD, Honorable Mention

2014 | Christopher R. Ensor, PharmD, BCPS-CV, Writer of the Year

|

Amanda Ingemi, PharmD, First Runner-Up

|

Simon Urschel, MD, Honorable Mention

2015 | Pamela S. Combs, PhD, RN, Writer of the Year

|

Manreet Kanwar, MD, First Runner-Up

|

Oveimar De la Cruz, MD, Honorable Mention

|

Heather T. Henderson, MD, Honorable Mention

|

Simon Urschel, MD, Honorable Mention

|

Erin Wells, RN, BSN, CPN, Honorable Mention

2016 | Kyle Dawson, PharmD, MBA, BCPS, Writer of the Year

|

Adam Cochrane, PharmD, BCPS, First Runner-Up

|

Christa Kirk, PharmD, First Runner-Up

|

Angela Velleca, RN, BSN, CCTC, Honorable Mention

|

Erin Wells, RN, BSN, CPN, Honorable Mention

2017 | Quincy Young, PhD, RPsych, Writer of the Year

|

Monica Horn, RN, First Runner-Ups

|

Melissa Cousino, PhD, Honorable Mention

|

Erin Wells, RN, BSN, CPN, Honorable Mention

# ABSTRACT AWARDS:

## PHILIP K. CAVES AWARD

1983  | Robbin G. Cohen, MD

---|---

1984  | Hermann Reichenspurner, MD

1985  | Michael A. Breda, MD

1986  | Stuart J. Knechtle, MD

1987  | Wim Van Der Bij, MD

1988  | Charles D. Fraser, Jr., MD

1989  | A.M. Wood, MD

1990  | Andres J. Duncan, MD

1991  | A. Jiminez, MD

1992  | David P. Kapelanski, MD

1993  | David Marshman, MD

1994  | Jobst Winter, MD

|

Alain Chapelier, MD

1995  | Elizabeth A. Davis, MD

1996  | Moninder S. Bhabra, MD

1997  | Simon D. Eiref, MD

1998  | Carla C. Baan, MD

1999  | Joerg Koglin, MD

2000  | Michael P. Fischbein, MD

2001  | Alexander S. Krupnick, MD

2002  | Peter Blaha, MD

2003  | Sigrid Sandner, MD

2004  | M.D. Peterson, MD

2005  | Sigrid Sandner, MD

|

Frank D'Ovidio, MD

2006  | Gregor Warnecke, MD

2007  | Heather E. Merry, MD

2008  | Satish N. Nadig, MD

2009  | Howard Huang, MD

2010  | Tobias Deuse, MD, PhD

2011  | Ankit Bharat, MD

2012  | Simo Syrjälä, MD

2013  | Alexey Dashkevich, MD

2014 | Jessica Spahn

2015 | Simon Pecha, MD

2016 | Corey E. Tabit, MD

## NURSING, HEALTH SCIENCES & ALLIED HEALTH EXCELLENCE IN RESEARCH AWARD

2005  | Mary Amanda Dew, PhD

---|---

2006  | Kathleen L. Grady, PhD, RN

2007  | Christiane Kugler, PhD

2008  | Annette DeVito Dabbs, RN, PhD

2009  | Connie White-Williams, MSN

2010  | Bronwyn Levvey, RN

2011  | Samantha J. Anthony, PhD, MSW

2012  | Kate Hayes, MPhysio (Cardio)

2013  | Jane Haines, DNP, RN, CMSRN

2014 | Louise Fuller, PT

2015 | Catherine Murks, PhD, APN

2016 | Fabienne Dobbels, MSc, PhD

## JFTC CLINICAL CASE DILEMMAS IN THORACIC TRANSPLANTATION BEST PRESENTATION AWARD

2011  | Michelle M. Kittleson, MD, PhD

---|---

2012  | Erin Albers, MD

2013  | Mustafa Ahmed, MD

2014 | Lauren Sacha

2015 | Ankit Bharat, MD

2016 | Yasufumi Goda, MD

## ISHLT BRANISLAV RADOVANCEVIC MEMORIAL BEST MCSD PAPER AWARD (supported by Thoratec)

2009  | Nishant Shah, MD

---|---

2010  | Jose N. Nativi, MD

2012  | Arun Raghav Mahankali Sridhar, MD, MPH

2013  | Claire Watkins, MD

2014 | Jason O. Robertson, MD

# ACCREDIDATION INFORMATION  
CONTINUING MEDICAL EDUCATION INFORMATION

ACCME Accreditation Statement

The International Society for Heart and Lung Transplantation (ISHLT) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians and allied health professionals.

CME Credit Designation Statement

ISHLT designates this live activity for a maximum of 32 _AMA PRA Category 1 Credits_ ™. Participants should claim only the credit commensurate with the extent of their participation in the activity.

ABTC Accreditation

The ABTC Board of Governors has granted a total of 32.0 Category 1 Continuing Education Points for Transplant Certification (CEPTCs) to the International Society for Heart & Lung Transplantation's ISHLT 37th Annual Meeting and Scientific Sessions.

ACPE Accreditation

 **Pharmacists**

Amedco is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. Successful completion of this program qualifies for up to 18.5 contact hours. Full attendance is required. No partial contact hours will be awarded for partial attendance. Unique Activity Numbers: 0453-9999-17-002-L04-P through 0453-9999-17-039-L04-P.

ANCC Accreditation

Amedco is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation. This course is co-provided by Amedco and the International Society for Heart and Lung Transplantation (ISHLT). Maximum of 32.00 contact hours.

Disclosure

Current guidelines state that participants in continuing medical and allied health profession education activities must be made aware of any affiliation or financial interest that may affect the program content or a speaker's presentation. Planners, Faculty, and Chairs participating in this meeting are required to disclose to the program audience any real or apparent conflict(s) of interest related to the content of their presentations or service as Chair/Planner. These disclosures will be distributed at the meeting. Additionally, all speakers have been asked to verbally disclose at the start of their presentation any financial interest or affiliations and to indicate if a product they are discussing is not labeled for the use under discussion or is still investigational.

Educational Objectives

The International Society for Heart and Lung Transplantation is a leading organization providing education for medical professionals involved in heart and lung transplantation. Because of the rapid advances in medicine in general and transplantation medicine specifically, transplant professionals are in need of regular opportunities to update and maintain their knowledge of advances and changes in transplant medicine. This meeting is designed to address their needs.

Educational Goals

The educational goals of this activity are: to enable participants to learn about current practices, emerging technologies, and medical advances related to heart and lung transplantation and end-stage heart and lung disease and to provide a forum for participants to engage in discussion, debate, and examination regarding the efficacy and applicability of these current practices, emerging technologies, and medical advances.

Target Audience

The audience for this program includes physicians, surgeons, scientists, pharmacists, nurses, transplant coordinators and other allied health and social science professionals engaged in the practice of heart and lung transplantation, the management and treatment of heart and lung transplant recipients, the management and treatment of patients with end-stage heart or lung disease, basic science or clinical research related to these fields, or specialties which cause them to become involved in the treatment of transplant recipients or patients with end stage heart or lung disease.

Learning Objectives

  1. At the conclusion of this meeting, participants will have improved competence and professional performance in the areas of understanding the latest information and approaches regarding transplant research, surgical techniques, medical therapies, donor management, and patient management for the treatment of patients suffering from end stage heart and lung disease
  2. At the conclusion of this meeting, participants will have improved competence and professional performance in the areas of understanding the state-of-the-art treatment approaches, risk factors, risk management approaches, patient selection criteria, disease prevention strategies, outcome implications, and psychosocial management strategies for patients with end stage heart and lung failure.
  3. At the conclusion of this meeting, participants will have improved competence and professional performance in the areas of understanding emerging technologies, medical advances, and the clinical applications of basic science models of end stage heart and lung disease management and prevention.

# UNRESTRICTED EDUCATIONAL GRANTS

The International Society for Heart and Lung Transplantation extends its heartfelt gratitude to the following companies for their unrestricted educational grants in support of the **37** th **Annual Meeting and Scientific Sessions:**

Actelion Pharmaceuticals

Bayer

Gilead Sciences

United Therapeutics

# COMMERCIAL SUPPORT

The International Society for Heart and Lung Transplantation is grateful for the support of the following companies for the Society and its endeavors in 2017:

Tier 1

Medtronic

Tier 2

Abbott

Actelion Pharmaceuticals

Bayer

United Therapeutics

Tier 3

Gilead Sciences

Transmedics

Tier 4

Abiomed

Genentech

One Lambda/Thermo Fisher

XVIVO

# HIGHLIGHTS OF THE MEETING

## Basic Science and Translational Research

The basic science and translational research symposia will feature diverse and dynamic speakers who are internationally recognized leaders in the field. We hope that each session will bring together in one room basic scientists as well as clinical researchers and clinicians who wish to further discuss and explore topics in heart and lung failure and transplantation. In Not CAVing to CLADtastrophy: Emerging Mechanisms in Chronic Heart and Lung Allograft Disease **,** experts will review endothelial biology, innate immunity, and antibody-based immunology in both heart and lung allograft dysfunction. The speakers will also explore the potential clinical implications of the available data. How to Mend a Broken Heart: Approaches for Cardiac Regeneration will be an exciting state-of-the-art set of lectures by thought-provoking speakers and experts in tissue engineering and cell therapy for heart failure who will discuss hurdles and perspectives of stem cell therapy on the way to clinical application. We will explore the evolving field of the microbiome in Living in a 'Bacterial' World: Microbiome in Thoracic Transplantation **.** The intricacies of the microbiome's effects on health disease, on post-transplant immunology, and specifically on heart and lung transplantation will be addressed. In addition to these three primary symposia, other talks focused on basic and translational research have been incorporated into other symposia in order to create a well-rounded, high-quality program for the attendees.

## Heart Failure and Transplantation

Our goal is to advance attendee's knowledge of specific heart failure entities and controversies in heart transplantation. We begin with Cardiogenic Shock: Types, Teams and Tactics **–** defining shock types, care delivery and bridging strategies. Three additional symposia **\- 1)** Getting to the Heart of Muscular Dystrophies **, 2)** Chagasic Cardiomyopathy: Lessons to Be Learned **,** and **3)** The Tsunami of Adult Congenital Heart Disease Patients Who Need Advanced Therapies: Are We Prepared? **–** will explore less well known but growing etiologies of heart failure and their management, including the use of circulatory support and implications for post-transplant management. As an international community, we share a donor organ shortage, and the symposium Making Every Heart Count will discuss optimizing the use of donor organs. Controversy remains about when to proceed with combined heart-lung, heart-kidney, or heart-liver transplantation, topics that will be tackled in A Tale of Two Organs: Selecting and Managing Multi-Organ Transplant Recipients **.** To round things out, two symposia will be devoted to topics where consensus conferences have been held, but we still have a lot to learn: PGD and Vasoplegia After Heart Transplantation: Sink or Swim **** and **** Dealing with Antibodies Before and After Heart Transplant: Do We Have New Arrows in our Quiver? **** Join us in San Diego for the opportunity of a lifetime to learn from each other!

## Infectious Diseases

ID content at ISHLT 2017 will kick off with the ISHLT Academy: Core Competencies in Infectious Diseases all day on Tuesday (separate registration required). The remainder of the meeting will feature an exciting line-up of ID content throughout the program, concentrated on the first two days of the meeting to make access to the presentations as convenient as possible for those ID specialists who cannot commit a week away from work. We start with a joint symposium featuring ISHLT and ESCMID speakers discussing Ongoing Challenges in Transplant Infectious Diseases, including fungi, multidrug resistant bacteria, and viruses including HCV, HIV, and EB. Following that we present Those Darn CARVs and learn about respiratory viruses in lung transplantation, the clinical and basic science correlations with CLAD, as well as treatment options and novel therapeutics in the pipeline. We then go Around the World in 80 Days to learn from experts about transplantation in areas endemic for Zika virus, tuberculosis, and HBV along with providing valuable advice for our patients when they travel. _Mycobacterium abscessus_ has come of age with its very own symposium where we learn about Taming of the Shrew, with talks on epidemiology, clinical manifestations, and therapeutics. We end with a fiery debate to settle the issue of whether patients infected with _M. abscessus_ can be safely transplanted _._ Other content that will be of interest to ID attendees includes a symposium dedicated to Chagasic cardiomyopathy, a sunrise symposium on HIV and cardiothoracic transplantation, and presentations on the respiratory microbiome and virome analysis for monitoring of post-transplant immune status.

## Lung Transplantation

In times of a changing landscape in lung transplant management, this year's lung transplant symposia will focus on important universal themes, including careful recipient selection, sensible donor allocation, safe peri-transplant ECMO use, pragmatic post-transplant treatment strategies and meticulous post-transplant follow-up. Excellent speakers will highlight the do's and don'ts in There Is No Such Thing as Perfect: Selecting Recipients for Lung Transplantation, with emphasis on non-standard, controversial, rare or difficult transplant referrals. Recent results of implementing the 2015 US Lung Allocation Score **** model will be discussed in Lung Allocation Scores: Making the Complex Simple, or Just the Simple Complex?,but will also address how to further improve equity in organ allocation world-wide. Practicalities and controversies of ECMO bridging to transplant, as well as its post-transplant use, will be debated in **** ECMO in Lung Transplantation: Sensational Success or Fantastic Failure? Light will be shed on novel post-transplant treatment strategies in Extracorporeal Photophoresis: Shedding Light on Rejection? **** and in Bench to Bedside: How Advances in Immunobiology Shape the Care of Today's Lung Transplant Recipients. Finally, the need for a holistic approach to patient care will be addressed in Thinking Outside the Box: Extra-Pulmonary Management in Lung Transplantation, focusing on the most common extra-pulmonary problems encountered in lung transplant recipients during follow-up. We are convinced that the meaningful reflections on these themes presented during this meeting will positively shape the daily care of all our lung transplant recipients.

## Mechanical Circulatory Support

New ideas in MCS will be presented at ISHLT 2017 in San Diego. The symposium Mechanical Circulatory Support - The Interface of Design and Outcome will discuss the physical possibilities and ideas involved in designing mechanical pumps to perform better, reduce adverse events and become better connected to patients. In To Pulse or Not to Pulse? That is the Question, we will focus on the impact of pulsatility on brain and blood vessel function, as well as the design and rationale for pulsatile and counterpulsation technology. Dr. Mandeep Mehra will talk about pulsatility from a scientific and existential perspective. Walk with Me: Exercise Physiology in the VAD Patient will look at the physiology of exercise in LVAD patients, delving into the increasingly complex world of antibodies in MCS patients. More LVAD complications will be explored in the Aiming off Target symposium, focusing on the non-cardiac consequences of LVADs. Finally, a **joint ISHLT/ICCAC symposium** will involve members from both societies looking at **optimizing outpatient strategies** in managing LVAD patients. With these and other symposia, we believe the ISHLT 2017 MCS symposia will have something for everyone.

## Nursing, Health Sciences and Allied Health

Optimizing outcomes is a multidisciplinary endeavor that needs investments along the transplant continuum. Pre-transplant, there are many psychosocial risk factors that can be targeted for intervention. When Should We Call It Quits? The Efficacy of Interventions to Ameliorate Psychosocial Risk Factors will review the efficacy of treatments available to ameliorate psychosocial risk factors. The state-of-the-art of e-health technology in delivering care will be discussed in E-health, Wearables, Social Media and Big Data in Transplantation: Fancy Toys or True Care Innovations? Interactive communication options via social media and the value of the big data for transplantation will also be explored. Patient Reported Outcomes (PRO) are increasingly used to capture outcomes in transplantation. Completing the Picture: Patient Reported Outcomes as an Essential Source of Information in Evaluating Transplantation Outcomes __ will provide insights in the concept, measurement and application of PROs. Outcomes of pediatric transplant patients may be jeopardized due to specific challenges related to neurocognitive development, problems in communication with health care workers, and transition. Live Long and Prosper: Thriving after Pediatric Transplantation **** will focus on the psychosocial, behavioral challenges, as well as communication and developmental issues in pediatric transplant patients. Specific attention will be given to adolescence and models for transition.

## Pathology

This year's pathology symposium, Let's Get Personal! Precision Diagnostics in Thoracic Transplantation, combines pathology and basic science and covers the topical issue of precision medicine/diagnosis for delivering personalized treatment, molecular diagnosis including cell free DNA (liquid biopsies), microRNA, next generation sequencing, and transcriptome analysis of biopsy material. A highlight will be the future possibilities with genome editing using CRISPR-Cas9 technology. A Sunrise Symposium, Mixed Rejection (MR) of the Cardiac Allograft: The Next Frontier, will discuss the relevance of mixed cellular and antibody mediated rejection in relation to diagnosis, management, and clinical outcomes.

## Pediatric Thoracic Transplantation and Heart Failure

Difficult clinical situations sometimes require complex solutions. This year, the pediatric symposia will delve into difficult clinical situations that we all face in our practices. The Failing Fontan: Where Do We Go from Here? will discuss optimization of Fontan patients prior to transplant, timing of transplant listing, and multi-organ transplant options, as well as examine programmatic issues with taking on Fontan patients. HLA, AMR and DSA – Approaching Antibodies in Kids will examine antibodies before and after transplant, including how to measure antibodies, how to manage the allosensitized patient before transplant, and how to handle donor-specific antibodies and antibody-mediated rejection. Upcoming Opportunities and Challenges in Pediatric Lung Transplantation will address bridging to lung transplant via ECMO, changing indications in pediatric lung and heart-lung transplant, the limits of ABO-incompatible lung transplantation, and the Potts shunt in children with pulmonary hypertension. Lastly, Live Long and Prosper: Thriving after Pediatric Transplantation will include discussions of neurodevelopmental outcomes, the role of exercise and sports, recommendations for communicating with teenagers and young adults, and approaches for transition of children to adult transplant care.

## Pharmacy and Pharmacology

Pharmacy and pharmacology will be the buzz of the meeting with four symposia appealing to all areas of the ISHLT membership. In our Thursday afternoon symposium, **** Weeding Out Fact from Fiction: Exploring the Highs and Lows of Marijuana Use __ in the Transplant Population, we will explore whether or not marijuana in all its forms is actually detrimental for our patients and how programs can navigate this legal and clinical minefield. Back by popular demand, join us at the Thursday Sunrise symposium for Lifecycle Journey of Thrombosis in Mechanical Circulatory Support __ Patients. We discuss the latest insights into the science of thrombus formation and how surgical techniques and medications can combine to give the best outcomes for our patients. The HOPE act assures that HIV and Transplantation Isn't Going Away and our Friday Sunrise symposium focuses the clinician on this vital topic. Experts will provide clarity on the burning questions including: How should end-stage HIV associated lung and heart disease be optimally managed? What unique infectious risks do HIV positive donors and recipients present, and how can the transplant and HIV medications be managed in tandem to optimize care? During our Saturday Sunrise session, Pregnant - Scared? So Are We, an expert panel will present the facts of life for our female transplant and CHD populations, many of whom can now consider pregnancy. We will present the best and safest multidisciplinary management of pregnancy after transplantation.

## Pulmonary Hypertension

Pulmonary hypertension is once again at the forefront of the ISHLT Scientific Sessions with six outstanding and provocative symposia! Symposia will explore current controversies in **chronic thromboembolic disease** , intricacies of **ECMO in pre-capillary pulmonary hypertension** , as well as **novel cardiopulmonary hemodynamics** and their impact on right ventricular and kidney function. A sunrise symposium will highlight **similarities and differences in treatment of children and adults with pulmonary hypertension** focusing on the strategies to adopt from each other's practices. This year, we present a unique **joint symposium of the ISHLT in partnership with the Pulmonary Hypertension Association (PHA** ) which, along with the always exciting **"Great Debates in Pulmonary Hypertension,"** are two symposia that are NOT TO BE MISSED! We look forward to seeing you in sunny San Diego!

# HOTEL FLOOR PLANS

## Lobby Level

## **2** nd **Level - Harbor**

## **2** nd **Level - Seaport**

## **3** rd **Level - Harbor**

## **3** rd **Level - Seaport**

## **4** th **Level**

# POSTER MAPS

## Coronado Poster Hall Wednesday

## Harbor Poster Hall Wednesday

## Regatta Poster Hall Wednesday

## Seaport Poster Hall Wednesday

## Coronado Poster Hall Thursday

## Harbor Poster Hall Thursday

## Regatta Poster Hall Thursday

## Seaport Poster Hall Thursday

## Coronado Poster Hall Friday

## Harbor Poster Hall Friday

## Regatta Poster Hall Friday

## Seaport Poster Hall Friday

# ACRONYMS

To help you navigate your way through the meeting content and find those sessions most likely to be of interest to you, we have coded each session according to the primary professional audience it was designed for. These codes are explained as follows:

BSTR | Basic Science and Translational Research

---|---

EEP | Economics, Ethics, Public Policy

HF | Heart Failure (Adult)

HTX | Heart Transplantation (Adult)

ID | Infectious Diseases

LBCS | Late Breaking Clinical Science

LTX | Lung Transplantation (Adult)

MCS | Mechanical Circulatory Support (Adult)

NHSAH | Nursing, Heath Science, and Allied Health

PATH | Pathology

PEDS | Pediatrics

PHARM | Pharmacy and Pharmacology

PH | Pulmonary Hypertension

# SCIENTIFIC COUNCIL MEETINGS & NETWORKING RECEPTIONS

Council | Meeting Date and Location

---|---

|

Basic Science and Translational Research | Fri April 7, 11:30 AM - 1:30 PM (Seaport F-H)

Chronic Thromboembolic Pulmonary Hypertension | Wed Apr 5, 6:15 – 7:15 PM (La Jolla AB)

Heart Failure & Transplantation | Fri Apr 7, 11:30 AM - 1:30 PM (Grand Hall B)

Infectious Diseases | Wed Apr 5, 12:30 - 2:30 PM (Coronado A-C)

Junior Faculty and Trainees | Thurs Apr 6, 7:00 – 8:00 AM (Gaslamp A-C)

Mechanical Circulatory Support | Thurs Apr 6, 12:30 – 2:00 PM (Grand Hall A)

Nursing, Health Science, and Allied Health | Wed Apr 5, 12:30 - 2:30 PM (Grand Hall A)

Pathology | Fri Apr 7, 11:30 AM - 1:30 PM (Coronado A-C)

Pediatric Thoracic Transplantation & Heart Failure | Wed Apr 5, 12:30 - 2:30 PM (Seaport F-H)

Pharmacy and Pharmacology | Thurs Apr 6, 12:30 – 2:00 PM (Seaport F-H)

Pulmonary Hypertension | Wed Apr 5, 12:30 - 2:30 PM (Grand Hall D)

Pulmonary Transplantation | Thurs Apr 6, 12:30 – 2:00 PM (Grand Hall C)

COUNCIL NETWORKING RECEPTIONS

In response to feedback from Council members requesting more opportunities for networking at the ISHLT Annual Meetings, we are excited to announce the following Council receptions planned in association with respective evening poster sessions:

Council | Reception Date and Location

---|---

|

Basic Science and Translational Research | Fri Apr 7, 5:45 - 6:45 PM (Harbor Terrace)

Heart Failure & Transplantation | Wed Apr 5, 6:15 - 7:15 PM (Seaport Terrace)

Infectious Diseases | Wed Apr 5, 6:15 - 7:15 PM (Seaport Terrace)

Junior Faculty and Trainees | Wed Apr 5, 6:15 - 7:15 PM (Coronado Terrace)

Mechanical Circulatory Support | Thurs Apr 6, 6:15 - 7:15 PM (Seaport Terrace)

Nursing, Health Science, and Allied Health | Thurs Apr 6, 6:15 - 7:15 PM (Coronado Terrace)

Pathology | Fri Apr 7, 5:45 - 6:45 PM (Harbor Terrace)

Pediatric Thoracic Transplantation & Heart Failure | Wed Apr 5, 6:15 - 7:15 PM (Harbor Terrace)

Pharmacy and Pharmacology | Thurs Apr 6, 6:15 - 7:15 PM (Coronado Terrace)

Pulmonary Hypertension | Thurs Apr 6, 6:15 - 7:15 PM (Harbor Terrace)

Pulmonary Transplantation | Thurs Apr 6, 6:15 - 7:15 PM (Harbor Terrace)

# DAILY SCHEDULE

All meetings and activities will take place at the Manchester Grand Hyatt Hotel in San Diego, CA, USA, unless otherwise specified. All papers will be presented in English. Please check the ISHLT web site (www.ISHLT.org) for updates. This Final Program reflects the latest session schedule and room assignments.

## MONDAY, APRIL 3, 2017

4:00 PM - 8:00 PM

Academy Registration Open (Palm Foyer)

Speaker Ready Room Open _(Academy Faculty only_ ) (Balboa ABC)

## TUESDAY, APRIL 4, 2017

6:00 AM - 3:00 PM

Academy Registration Open (Palm Foyer)

6:00 AM - 8:00 PM

Speaker Ready Room Open (Balboa ABC)

7:45 AM – 12:50 PM

ISHLT ACADEMY: Master Class in Mechanical Circulatory Support (Seaport F-G)

7:45 AM – 5:15 PM

ISHLT ACADEMY: Core Competency Course in Pediatric and Adult Congenital MCS (Grand Hall A)

ISHLT ACADEMY: Core Competency Course in Infectious Diseases in Thoracic Transplantation and MCS (Grand Hall C)

8:00 AM - 2:00 PM

ISHLT Board of Directors Meeting (America's Cup A-D)

8:00 AM – 5:30 PM

ISHLT ACADEMY: Core Competency Course in Mechanical Circulatory Support (Grand Hall B)

1:45 PM – 6:50 PM

ISHLT ACADEMY: Master Class in Mechanical Circulatory Support (Gaslamp A-D)

2:00 PM - 6:00 PM

ISHLT Board/Committee/Council Leadership Orientation (Hillcrest A-D)

2:00 PM – 7:00 PM

ISHLT ACADEMY: Master Class in Pulmonary Hypertension (Seaport F-G)

4:00 PM - 8:00 PM

Annual Meeting Registration Open (Palm Foyer)

5:00 PM - 7:00 PM

International Thoracic Transplant Registry Committee Meeting (Old Town B)

6:00 PM – 8:00 PM

ISHLT Standards and Guidelines Committee Meeting (La Jolla AB)

## WEDNESDAY, APRIL 5, 2017

7:00 AM - 10:00 AM

Exhibitor Set-Up (Harbor A-H)

Poster Session 1 Mount (Seaport/Harbor/Regatta/Coronado Foyers, and Coronado D)

7:00 AM - 6:15 PM

Registration Open (Palm Foyer)

7:00 AM – 7:30 PM

Speaker Ready Room Open (Balboa ABC)

8:00 AM - 10:00 AM

SYMPOSIUM 1: Joint ISHLT/ICCAC Symposium: Besides the Surgery - How to Make VAD Patients Successful (Seaport A-E)

(MCS, HF, HTX, NHSAH)

SYMPOSIUM 2: When Should We Call It Quits? The Efficacy of Interventions to Ameliorate Psychosocial Risk Factors (Grand Hall A)

(HTX, HF, MCS, NHSAH)

SYMPOSIUM 3: Primary Graft Dysfunction (PGD) and Vasoplegia After Heart Transplantation: Sink or Swim (Grand Hall B)

(HTX, HF, MCS)

SYMPOSIUM 4: Thinking Outside the Box: Extra-Pulmonary Management in Lung Transplantation (Grand Hall C)

(LTX, BSTR, ID, NHSAH, PATH, PEDS, PHARM, PH)

SYMPOSIUM 5: Joint ISHLT/PHA Symposium: PH and Transplant: Where Do We Go from Here? (Grand Hall D)

(PH, HF, HTX, LTX, MCS, NHSAH, PEDS)

SYMPOSIUM 6: The Failing Fontan - Where Do We Go from Here? (Seaport F-H)

(PEDS, EEP, HF, HTX)

SYMPOSIUM 7: Joint ISHLT/ESCMID Symposium: Ongoing Challenges in Transplant Infectious Diseases (Coronado A-C)

(ID, HTX, LTX, MCS, PHARM)

9:00 AM - 7:00 PM

Press Office Open (Old Town A)

10:00 AM - 10:30 AM

Coffee Break (Harbor A-H)

10:00 AM - 7:15 PM

Exhibit Hall Open (Harbor A-H)

Industry Theater Open (Harbor I)

Poster Halls Open (Seaport/Harbor/Regatta/Coronado Foyers, and Coronado D)

10:30 AM - 12:30 PM

OPENING PLENARY SESSION (Seaport A-E)

(ALL)

12:30 PM - 2:30 PM

Lunch Break

Education Committee Meeting (Gaslamp B)

Grants & Awards Committee Meeting (Gaslamp A)

International and Inter-Society Coordination Committee (I2C2) Meeting (Gaslamp C)

Infectious Diseases Scientific Council Meeting (Coronado A-C)

ISHLT Mechanically Assisted Circulatory Support (IMACS) Registry Committee Meeting (Old Town B)

Junior Faculty Mentor Lunch Meeting (Mission Beach A-C)

Nursing, Health Sciences & Allied Health Scientific Council Meeting (Grand Hall A)

Pediatric Thoracic Transplantation and Heart Failure Scientific Council Meeting (Seaport F-H)

Pulmonary Hypertension Scientific Council Meeting (Grand Hall D)

Pulmonary Transplant Council Quality of Life (QOL) Workforce Meeting (La Jolla AB)

Registries and Databases Committee Meeting (Gaslamp D)

2:30 PM - 4:00 PM

ORAL SESSION 1: Too Thick or Too Thin? Bleeding and Thrombosis in MCS (Seaport A-E)

(MCS, HF, NHSAH, PHARM)

ORAL SESSION 2: Engineering for Perfection in MCS (Grand Hall A)

(MCS, HF, NHSAH)

ORAL SESSION 3: Moving DCD Forward: Thinking Inside the Box (Grand Hall B)

(HTX, BSTR, MCS)

ORAL SESSION 4: Donor Lung Allocation Strategies (Grand Hall C)

(LTX, EEP, NHSAH)

ORAL SESSION 5: Registries and Risk Scores in Pulmonary Hypertension: Updates, Lessons Learned, and Practice Changes (Grand Hall D)

(PH, HF, HTX, LTX, NHSAH, PEDS, PHARM)

ORAL SESSION 6: Pediatric Heart Failure: Diagnosis, Management, and Confronting Risk (Seaport F-H)

(PEDS, HF, HTX)

ORAL SESSION 7: Cutting Edge Updates in Infectious Diseases (Coronado A-C)

(ID, ALL)

4:00 PM - 4:30 PM

Coffee Break (Harbor A-H)

4:30 PM - 6:00 PM

ORAL SESSION 8: Bugs and Devices: A Bad Combination (Seaport A-E)

(MCS, ID, NHSAH, PHARM)

ORAL SESSION 9: MCS Surgery: Does Nuance Make a Master? (Grand Hall A)

(MCS, HF, NHSAH)

ORAL SESSION 10: Movement on the Heart Transplant Wait List: VADS, Exceptions and Antibodies (Grand Hall B)

(HTX, EEP, MCS, NHSAH)

ORAL SESSION 11: Improving Prognosis in Chronic Lung Allograft Dysfunction (Grand Hall C)

(LTX, BSTR, EEP, ID, NHSAH, PATH, PHARM)

ORAL SESSION 12: Innovation in Pediatric MCS (Seaport F-H)

(PEDS, MCS)

SYMPOSIUM 8: ECMO in Pre-Capillary PH: What is the Best Option for My Patient? (Grand Hall D)

(PH, HF, LTX, PEDS, PH)

SYMPOSIUM 9: JHLT at ISHLT: The Year in a Capsule (Coronado A-C)

(ALL)

6:00 PM - 6:15 PM

Break (Harbor A-H)

6:15 PM - 7:15 PM

Inaugural Chronic Thromboembolic Pulmonary Hypertension (CTEPH) Scientific Council Meeting (La Jolla A)

Exhibit Hall Opening Reception (Harbor A-H)

Council Networking Receptions:

Heart Failure and Transplantation (Seaport Terrace)

Infectious Diseases (Seaport Terrace)

Junior Faculty and Trainees (Coronado Terrace)

Pediatric Heart Failure and Transplantation (Harbor Terrace)

MODERATED POSTER SESSION 1:

Heart Failure (Seaport Foyer)

Heart Transplantation (Seaport Foyer)

Infectious Diseases (Seaport Foyer)

Junior Faculty Clinical Case Reports (Coronado D and Foyer)

**Mechanical Circulatory Support (Regatta** **Foyer)**

Pediatrics (Harbor Foyer)

MINI ORAL SESSION 1: Complicating Factors in MCS (Grand Hall A)

(MCS, HF, HTX, NHSAH, PHARM)

MINI ORAL SESSION 2: Donor Evaluation and Management: DBD and DCD (Grand Hall B)

(HTX, EEP, MCS)

MINI ORAL SESSION 3: Wretched Strangers: Mechanisms of Thoracic Organ Infection, Rejection and Tolerance (Grand Hall C)

(BSTR, EEP, HF, HTX, ID, LTX, PATH, PEDS, PHARM, PH)

MINI ORAL SESSION 4: Allocation, Bridging and Lung Allograft Assessment Strategies (Grand Hall D)

(LTX, BSTR, EEP, ID, MCS, NHSAH, PATH, PHARM)

MINI ORAL SESSION 5: The Hardware of MCS (Seaport F-H)

(MCS, HF, NHSAH)

MINI ORAL SESSION 6: Therapeutics in Advanced Heart and Lung Disease (Coronado A-C)

(PHARM, HTX, ID, LTX, MCS, NHSAH)

7:15 PM - 8:15 PM

Poster Session 1 Removal (Seaport/Harbor/Regatta/Coronado Foyers, and Coronado D)

7:30 PM - 10:00 PM

ICCAC Annual Meeting (Grand Hall D)

## THURSDAY, APRIL 6, 2017

6:00 AM - 7:30 PM

Speaker Ready Room Open (Balboa ABC)

7:00 AM - 10:00 AM

Poster Session 2 Mount (Seaport/Harbor/Regatta/Coronado Foyers)

7:00 AM – 6:15 PM

Registration Open (Palm Foyer)

7:00 AM - 8:00 AM

Junior Faculty and Trainees Scientific Council Meeting (Gaslamp A-C)

SUNRISE SYMPOSIUM 1: Walk With Me: Exercise Physiology in the LVAD Patient (Grand Hall A)

(MCS, ALL)

SUNRISE SYMPOSIUM 2: Chagasic Cardiomyopathy: Lessons To Be Learned (Grand Hall B)

(HF, HTX, ID, MCS)

SUNRISE SYMPOSIUM 3: Lifecycle Journey of Thrombosis in Mechanical Circulatory Support Patients (Grand Hall C)

(PHARM, HF, HTX, MCS, NHSAH)

SUNRISE SYMPOSIUM 4: Completing the Picture: Patient Reported Outcomes (PROs) as an Essential Source of Information in Evaluating Transplantation Outcomes (Grand Hall D)

(NHSAH, ALL)

SUNRISE SYMPOSIUM 5: Upcoming Opportunities and Challenges in Pediatric Lung Transplantation (Seaport F-H)

(PEDS, HF, LTX, MCS, PEDS, PH)

SUNRISE SYMPOSIUM 6: "Those Darn CARVs": Community Acquired Respiratory Viruses in Lung Transplant (Coronado A-C)

(ID, LTX, PATH, PHARM)

8:00 AM - 10:00 AM

SYMPOSIUM 10: Antibodies in MCS: The Phantom Menace (Seaport A-E)

(MCS, BSTR, HF, HTX, PEDS, PHARM)

SYMPOSIUM 11: Not CAVing to CLADtastrophy: Emerging Mechanisms of Chronic Heart and Lung Allograft Disease (Grand Hall A)

(BSTR, HTX, LTX, PATH, PHARM)

SYMPOSIUM 12: A Tale of Two Organs: Selecting and Managing Multi-Organ Transplant Recipients (Grand Hall B)

(HTX, ALL)

SYMPOSIUM 13: Lung Allocation Scores (LAS): Making the Complex Simple, or Just the Simple Complex? (Grand Hall C)

(LTX, ALL)

SYMPOSIUM 14: Chronic Thromboembolic Pulmonary Hypertension (CTEPH): Current Controversies and New Directions (Grand Hall D)

(PH)

SYMPOSIUM 15: HLA, AMR and DSA - Approaching Antibodies in Kids (Seaport F-H)

(ALL)

SYMPOSIUM 16: "Around the World in 80 Days": Infectious Challenges in Cardiothoracic Transplantation (Coronado A-C)

(ID, HF, HTX, LTX)

9:00 AM - 7:00 PM

Press Office Open (Old Town A)

10:00 AM - 10:30 AM

Coffee Break (Harbor A-H)

10:00 AM - 7:00 PM

Industry Theater Open (Harbor I)

10:00 AM - 7:15 PM

Exhibit Hall Open (Harbor A-H)

Poster Halls Open (Seaport/Harbor/Regatta/Coronado Foyers)

10:30 AM - 12:30 PM

PLENARY SESSION (Seaport A-E)

(ALL)

12:30 PM - 2:00 PM

Lunch Break

International Pediatric Heart Failure Registry Meeting (Old Town B)

JHLT Editorial Board Lunch Meeting (Gaslamp A-C)

Mechanical Circulatory Support Scientific Council Meeting (Grand Hall A)

Pharmacy and Pharmacology Scientific Council Meeting (Seaport F-H)

Pulmonary Transplantation Scientific Council Meeting (Grand Hall C)

2:00 PM - 3:30 PM

ORAL SESSION 13: Contemporary LVAD Trials - Same Old Song or New Tune? (Seaport A-E)

(MCS, HF, HTX, NHSAH)

ORAL SESSION 14: Measure for Measure: In- and Ex-Vivo Cellular and Molecular Approaches for Thoracic Organ Tailoring (Grand Hall A)

(BSTR, HF, HTX, LTX, MCS, NHSAH, PATH, PEDS, PHARM)

ORAL SESSION 15: Therapies and Monitoring After Heart Transplantation (Grand Hall B)

(HTX, BSTR, NHSAH, PHARM)

ORAL SESSION 16: The Rise of the Machines: ECLS and EVLP in Lung Transplantation (Grand Hall C)

(LTX, BSTR, EEP, ID, LTX, MCS, NHSAH, PATH, PHARM)

ORAL SESSION 17: What's Up Next in Pulmonary Hypertension Research? (Grand Hall D)

(PH, BSTR, HF, LTX)

ORAL SESSION 18: Contemporary Challenges in Pediatric Heart Transplant (Seaport F-H)

(PEDS, HTX, PATH)

ORAL SESSION 19: Junior Faculty Clinical Case Dilemmas in Thoracic Transplantation: The Best of the Best (Coronado A-C)

(ALL)

3:30 PM - 4:00 PM

Coffee Break (Harbor A-H)

2018 Symposium Planning Committee Meeting (Hillcrest A-D)

4:00 PM - 6:00 PM

SYMPOSIUM 17: To Pulse or Not To Pulse? That is the Question (Seaport A-E)

(ALL)

SYMPOSIUM 18: Weeding Out Fact from Fiction - the Highs and Lows of Marijuana Use in Transplant (Grand Hall A)

(PHARM, ALL)

SYMPOSIUM 19: Cardiogenic Shock: Types, Teams and Tactics (Grand Hall B)

(HF, HTX, MCS)

SYMPOSIUM 20: ECMO in Lung Transplantation: Sensational Success or Fantastic Failure? (Grand Hall C)

(LTX, ALL)

SYMPOSIUM 21: Cardiopulmonary Hemodynamics, the Right Ventricle, and the Kidney: Connecting All the Dots (Grand Hall D)

(PH, HF, HTX, LTX, MCS)

SYMPOSIUM 22: Let's Get Personal! Precision Diagnostics in Thoracic Transplantation (Seaport F-H)

(PATH, ALL)

SYMPOSIUM 23: Taming of the Shrew: Mycobacterium Abscessus in Lung Transplantation (Coronado A-C)

(ID, ALL)

6:00 PM - 6:15 PM

Break (Harbor A-H)

6:00 PM - 7:00 PM

Past President's Meeting (Gaslamp D)

6:15 PM - 7:15 PM

Wine & Cheese Reception (Harbor A-H)

Council Networking Receptions:

Mechanical Circulatory Support (Seaport Terrace)

Nursing, Health Sciences & Allied Health (Coronado Terrace)

Pharmacy and Pharmacology (Coronado Terrace)

Pulmonary Hypertension (Harbor Terrace)

Pulmonary Transplantation (Harbor Terrace)

MODERATED POSTER SESSION 2:

Economics, Ethics, Public Policy (Coronado Foyer)

Heart Transplantation (Regatta Foyer)

Lung Transplantation (Harbor Foyer)

Mechanical Circulatory Support (Seaport Foyer)

Nursing, Health Sciences, Allied Health (Coronado Foyer)

Pharmacy and Pharmacology (Coronado Foyer)

Pulmonary Hypertension (Harbor Foyer)

MINI ORAL SESSION 7: Factors that Drive Success in MCS (Grand Hall A)

(MCS, EEP, HF, NHSAH)

MINI ORAL SESSION 8: Infections, Induction and IVIG (Grand Hall B)

(HTX, EEP, ID, MCS)

MINI ORAL SESSION 9: Novel Strategies and Mechanisms in Lung Preservation, Heart Failure and Assist Devices (Grand Hall C)

(BSTR, HTX, ID, LTX, MCS, PEDS, PHARM)

MINI ORAL SESSION 10: Challenges in Lung Transplantation (Grand Hall D)

(LTX, EEP, ID, NHSAH, PATH, PHARM)

MINI ORAL SESSION 11: Outcomes in MCS (Seaport F-H)

(MCS, HF, HTX)

MINI ORAL SESSION 12: Hot Topics in Pediatric Heart Transplantation (Coronado A-C)

(PEDS, BSTR, HTX)

7:15 PM - 8:15 PM

Poster Session 2 Removal (Seaport/Harbor/Regatta/Coronado Foyers)

8:00 PM – 9:30 PM

ISHLT President's Cocktail Reception (USS Midway Museum)

## FRIDAY, APRIL 7, 2017

6:00 AM – 7:00 PM

Speaker Ready Room Open (Balboa ABC)

7:00 AM - 10:00 AM

Poster Session 3 Mount (Seaport/Harbor/Regatta/Coronado Foyers)

7:00 AM – 5:45 PM

Registration Open (Palm Foyer)

7:00 AM - 8:00 AM

SUNRISE SYMPOSIUM 7: Getting to the Heart of Muscular Dystrophies (Grand Hall A)

(ALL)

SUNRISE SYMPOSIUM 8: Live Long and Prosper: Thriving After Pediatric Transplantation (Grand Hall B)

(PEDS, EEP, HF, HTX, LTX, MCS, NHSAH, PHARM)

SUNRISE SYMPOSIUM 9: Mixed Rejection (MR) of the Cardiac Allograft: The Next Frontier (Grand Hall C)

(PATH, BSTR, HF, HTX)

SUNRISE SYMPOSIUM 10: Contrasts and Similarities in Children and Adults: IPAH, Portopulmonary Hypertension, and Perioperative Management (Grand Hall D)

(PH, BSTR, HF, LTX, NHSAH, PEDS, PHARM)

SUNRISE SYMPOSIUM 11: There is No Such Thing as Perfect: Selecting Recipients for Lung Transplantation (Seaport F-H)

(LTX, ID, NHSAH, PEDS)

SUNRISE SYMPOSIUM 12: HIV and Transplantation: It Isn't Going Away... (Coronado A-C)

(PHARM, HTX, ID, LTX, NHSAH, PEDS, PH)

8:00 AM - 9:30 AM

ORAL SESSION 20: New and Improving? Evolving Outcomes with MCS (Seaport A-E)

(MCS, EEP, HF, HTX, NHSAH)

ORAL SESSION 21: New Fixes for an Old Problem: Preventing, Diagnosing, and Treating Pump Thrombosis (Grand Hall A)

(MCS, HF, NHSAH, PHARM)

ORAL SESSION 22: Does Risk Reap Reward? Expanding the Heart Donor Pool (Grand Hall B)

(HTX, BSTR)

ORAL SESSION 23: Choosing Right: Lung Recipient Selection and Management (Grand Hall C)

(LTX, BSTR, EEP, NHSAH, PHARM)

ORAL SESSION 24: An Amalgamation of Support in Heart Failure (Grand Hall D)

(HF, MCS, NHSAH, PHARM)

ORAL SESSION 25: Improving Outcomes in Pediatric Lung Transplantation (Seaport F-H)

(PEDS, ID, LTX)

ORAL SESSION 26: Philip K. Caves Award Candidate Presentations (Coronado A-C)

(ALL)

9:00 AM - 7:00 PM

Press Office Open (Old Town A)

9:30 AM - 10:00 AM

Coffee Break (Harbor A-H)

Annual Business Meeting (Seaport A-E)

9:30 AM - 4:00 PM

Exhibit Hall Open (Harbor A-H)

Industry Theater Open (Harbor I)

9:30 AM - 6:45 PM

Poster Halls Open (Seaport/Harbor/Regatta/Coronado Foyers)

10:00 AM - 11:30 AM

ORAL SESSION 27: The Leaking Gut - New Strategies for GI Bleeding in MCS (Seaport A-E)

(MCS, HF, NHSAH, PHARM)

ORAL SESSION 28: The Heart of the Matter: Cardiac Substrate in MCS Therapy (Grand Hall A)

(MCS, HF)

ORAL SESSION 29: Donor Utilization and Allocation in Heart Transplantation: Lessons to Learn (Grand Hall B)

(HTX, HF)

ORAL SESSION 30: Novel Mechanisms in Chronic Lung Allograft Dysfunction (Grand Hall C)

(LTX, BSTR, ID, PATH, PHARM)

ORAL SESSION 31: Saved by the Bell: Overcoming Adherence and Frailty (Grand Hall D)

(NHSAH, ALL)

ORAL SESSION 32: The Tell Tale Heart: From Signals to Biomarkers (Seaport F-H)

(BSTR, HF, HTX, MCS, NHSAH, PATH, PEDS, PH, PHARM)

Oral Session 33: PATH to Better Outcomes: Diagnostics in Heart and Lung Transplantation (Coronado A-C)

(PATH, BSTR, HTX, LTX, PEDS)

11:30 AM - 1:30 PM

Lunch Break

Basic Science and Translational Research Scientific Council Meeting (Seaport F-H)

DCD Registry Committee Lunch Meeting (Gaslamp D)

Heart Failure and Transplantation Scientific Council Meeting (Grand Hall B)

IMACS Users Group Meeting (Gaslamp A-C)

Pathology Scientific Council Meeting (Coronado A-C)

1:30 PM - 3:30 PM

SYMPOSIUM 24: Aiming Off Target: Non-Cardiac Consequences of LVAD Support (Seaport A-E)

(MCS, BSTR, HF)

SYMPOSIUM 25: Dealing with Antibodies Before and After Heart Transplant: Do We Have New Arrows in our Quiver? (Grand Hall A)

(ALL)

SYMPOSIUM 26: Making Every Heart Count (Grand Hall B)

(HTX, EEP, HF, HTX)

SYMPOSIUM 27: Bench to Bedside: How Advances in Immunology Shape the Care of Today's Lung Transplant Recipients (Grand Hall C)

(LTX, BSTR, HTX, ID, NHSAH, PATH, PEDS, PHARM)

SYMPOSIUM 28: Great Debates in Pulmonary Hypertension (Grand Hall D)

(PH, ALL)

SYMPOSIUM 29: How to Mend a Broken Heart: Approaches for Cardiac Regeneration (Seaport F-H)

(BSTR, HF, HTX, PATH, PHARM)

SYMPOSIUM 30: E-Health, Wearables, Social Media and Big Data in Transplantation: Fancy Toys or True Care Innovations? (Coronado A-C)

(NHSAH, ALL)

3:30 PM - 4:00 PM

Coffee Break (Harbor A-H)

4:00 PM - 5:30 PM

ORAL SESSION 34: Short-Term MCS for Shock: New Paradigms (Seaport A-E)

(MCS, HF, HTX, NHSAH)

ORAL SESSION 35: Heart Failure in MCS (Grand Hall A)

(MCS, HF, HTX, PH)

ORAL SESSION 36: CAV: New Insights to an Old Problem (Grand Hall B)

(HTX, BSTR, PATH, PHARM)

ORAL SESSION 37: Impact of Donor Characteristics on Lung Transplant Outcomes (Grand Hall C)

(LTX, BSTR, EEP, MCS, NHSAH)

ORAL SESSION 38: The Nightmare of Primary Cardiac Allograft Dysfunction (Grand Hall D)

(HTX, MCS, PHARM)

ORAL SESSION 39: Early Career Scientist Award in Transplantation Finalist Presentations (Seaport F-H)

(BSTR, HTX, ID, LTX, PATH, PEDS, PHARM)

ORAL SESSION 40: Drugs, Bleeding and Enzymes ... Oh My! (Coronado A-C)

(PHARM, HTX, ID, LTX, MCS, NHSAH)

5:30 PM - 5:45 PM

Break (Seaport Foyer)

5:45 PM - 6:45 PM

Wine and Cheese Reception (Seaport/Harbor/Regatta/Coronado Foyers)

Council Networking Receptions:

Basic Science and Translational Research (Harbor Terrace)

Pathology (Harbor Terrace)

MODERATED POSTER SESSION 3:

Basic Science and Translational Research (Harbor Foyer)

Heart Transplantation (Coronado Foyer)

Junior Faculty Clinical Case Reports (Coronado Foyer)

Mechanical Circulatory Support (Seaport Foyer)

Pathology (Harbor Foyer)

Lung Transplantation (Regatta Foyer)

MINI ORAL SESSION 13: Controversies in Heart Transplantation (Grand Hall A)

(HTX, MCS)

MINI ORAL SESSION 14: Recipient Risk Factors Affecting Outcome after Lung Transplantation (Grand Hall B)

(LTX, BSTR, EEP, ID, NHSAH, PATH, PHARM)

MINI ORAL SESSION 15: Pediatric Heart Failure, MCS, and Peri-Transplant Issues (Grand Hall C)

(PEDS, HF, HTX, MCS)

MINI ORAL SESSION 16: Assessing and Managing the Failing Right Ventricle (Grand Hall D)

(PH, BSTR, HF, HTX, LTX, PHARM)

MINI ORAL SESSION 17: Progress in MCS Outcomes (Seaport F-H)

(MCS, HF, HTX, ID, NHSAH, PHARM)

MINI ORAL SESSION 18: Patient Centered Outcomes in Advanced Heart and Lung Disease (Coronado A-C)

(NHSAH, ALL)

6:45 PM - 7:45 PM

Poster Session 3 Removal (Seaport/Harbor/Regatta/Coronado Foyers)

## SATURDAY, APRIL 8, 2017

6:00 AM - 1:30 PM

Speaker Ready Room Open (Balboa ABC)

7:00 AM - 12:00 PM

Registration Open (Palm Foyer)

7:00 AM - 8:00 AM

SUNRISE SYMPOSIUM 13: Mechanical Circulatory Support - The Interface of Design and Outcome (Grand Hall A)

(MCS, BSTR, EEP, HF, HTX)

SUNRISE SYMPOSIUM 14: The Tsunami of Adult Congenital Heart Disease (ACHD) Patients Who Need Advanced Therapies: Are We Prepared? (Grand Hall B)

(HTX, HF, LTX, MCS, PEDS, PH)

SUNRISE SYMPOSIUM 15: Extracorporeal Photopheresis: Shedding Light on Rejection? (Grand Hall C)

(LTX, BSTR, HTX, ID, NHSAH, PATH, PEDS, PHARM)

SUNRISE SYMPOSIUM 16: Pregnant - Scared? So Are We.... Management of Pregnancy in Our Complex Patients (Seaport F-H)

(PHARM, HTX, LTX, MCS, NHSAH, PEDS)

SUNRISE SYMPOSIUM 17: Living in a 'Bacterial' World: Microbiome in Thoracic Transplantation (Coronado A-C)

(BSTR, ALL)

8:00 AM - 9:30 AM

ORAL SESSION 41: The Rhythm is Going to Get You: EP Issues in MCS (Seaport A-E)

(MCS, HF, NHSAH)

ORAL SESSION 42: The Weighting Game: Impact of Obesity, Age, and Other Comorbidities in MCS (Grand Hall A)

(MCS, HF, HTX, NHSAH)

ORAL SESSION 43: In the Mix of Heart Failure (Grand Hall B)

(HF, BSTR, NHSAH, PHARM)

ORAL SESSION 44: Optimizing Early Outcomes after Lung Transplantation (Grand Hall C)

(LTX, BSTR, ID, PATH, PHARM)

ORAL SESSION 45: Heart Transplant in Special Populations (Grand Hall D)

(HTX, HF, MCS)

ORAL SESSION 46: Rogue One: A Graft Wars Story of Rejection and Tolerance (Seaport F-H)

(BSTR, HF, HTX, LTX, PATH, PEDS, PHARM)

9:30 AM - 9:45 AM

Coffee Break (Seaport Foyer)

9:45 AM - 11:45 AM

PLENARY SESSION (Seaport A-E)

(ALL)

11:45 AM - 12:00 PM

Coffee Break (Seaport Foyer)

12:00 PM - 1:30 PM

ORAL SESSION 47: Not the Usual Suspects: Driving Outcomes in MCS (Seaport A-E)

(MCS, HF, HTX, NHSAH)

ORAL SESSION 48: Seeing the Patient Beyond the Device (Grand Hall A)

(MCS, HF, NHSAH)

ORAL SESSION 49: Antibodies and Other Determinants of Cardiac Rejection: Let's ROCK and Rho (Grand Hall B)

(HTX, BSTR, EEP, PEDS, PHARM)

ORAL SESSION 50: Influencing Long-term Outcomes in Lung Transplantation (Grand Hall C)

(LTX, BSTR, ID, NHSAH, PEDS, PHARM)

ORAL SESSION 51: Optimizing Outcomes After Heart Transplantation: Predictors and Risk Scores (Grand Hall D)

(HTX, MCS, PATH)

ORAL SESSION 52: Does Size Matter? Center Volume, Urgency Status and Managing Complications (Seaport F-H)

(EEP, HF, HTX, LTX, MCS, NHSAH, PEDS, PHARM)

ORAL SESSION 53: Getting to the Heart of the Matter: Psychosocial Factors Predict Outcomes in Transplant and MCS (Coronado A-C)

(NHSAH, ALL)

12:00 PM - 6:00 PM

ISHLT Board of Directors Meeting (America's Cup A-D)

# Wednesday, April 05, 2017

8:00 AM - 10:00 AM

## SYMPOSIUM 01: Joint ISHLT/ICCAC Symposium: Besides the Surgery - How to Make VAD Patients Successful

Location:

Seaport A-E

Target Audience:

MCS, HF, HTX, NHSAH

**Chairs:**

Ivan Netuka, MD, PhD, and Thomas Schlöglhofer, BSc

**Session Summary:** This session, supported by a collaborative effort with the International Consortium of Circulatory Assist Clinicians (ICCAC), is designed to discuss questions frequently asked by MCS Teams around the world regarding multidisciplinary program structure, practice guidelines, VAD education including simulation labs, cost-effectiveness and international aspects in care delivery from a program perspective, and with patients, families, and staff caring for them.

8:00 AM

Multidisciplinary Approaches to Optimize VAD Patient Management in High Volume Centers

Friedrich Kaufmann, MSc, German Heart Institute, Berlin, Germany

**8:12 AM** _Q &A_

8:17 AM

Caring for the Pediatric VAD Patient - They Aren't Just Small Adults

Jodie Lantz, MSN, RN, PCNS-BC, Children's Health Dallas, Dallas, TX, USA

**8:29 AM** _Q &A_

8:34 AM

Keep Them at Home: Interventions to Prevent Readmission

Lori Edwards, MSN, Inova Fairfax Hospital, Falls Church, VA, USA

**8:46 AM** _Q &A_

8:51 AM

Measuring and Managing Blood Pressure in CF-LVAD recipients

Brent C Lampert, DO, Ohio State University, Columbus, OH, USA

**9:03 AM** _Q &A_

9:08 AM

Echocardiography in LVAD Recipients: How and What to Measure?

Peter J Bergin, MBBS, FRACP, Alfred Hospital, Melbourne, Australia

**9:20 AM** _Q &A_

9:25 AM

Optimizing Unloading with Right Heart Catheterization Ramp Studies

Nir Uriel, MD, University of Chicago, Chicago, IL, USA

**9:37 AM** _Q &A_

9:42 AM

Do We Need Antiplatelet Drugs and Anticoagulants to Manage LVAD Patients?

Haifa Lyster, MSc, Royal Brompton Harefield Hospital, Middlesex, United Kingdom

**9:54 AM** _Q &A_

8:00 AM - 10:00 AM

## SYMPOSIUM 02: When Should We Call It Quits? The Efficacy of Interventions to Ameliorate Psychosocial Risk Factors

Location:

Grand Hall A

Target Audience:

HTX, HF, MCS, NHSAH

**Chairs:**

Lavanya Bellumkonda, MD, and Jane MacIver, RN, NP, PhD

**Session Summary:** This session will start by briefly reviewing the literature on psychosocial risk factors including: psychiatric illness, poor social support, medical non-adherence and substance abuse. The majority of the presentations will, however, focus on the interventions available to mitigate the risks associated with each variable and the efficacy of those interventions. Thus, the focus is how to use the psychosocial assessment as a means of problem identification for intervention rather than as a gate keeping function. A panel discussion with all speakers will conclude this session.

8:00 AM

The Impact of Psychiatric Risk Factors on Outcomes in Heart Failure, MCS and Cardiothoracic Transplant Patients

Heike Spaderna, PhD, University of Trier, Trier, Germany

8:15 AM

The Efficacy of Interventions for Psychiatric Risk Factors in Cardiothoracic Transplantation and MCS

Quincy Young, PhD, RPsych, St. Paul's Hospital, Vancouver, BC, Canada

8:30 AM

It Takes a Village: Social Support and Social Determinants of Health in MCS and Cardiothoracic Transplantation as Potential Targets for Intervention

Michael G. Petty, PhD, RN, CNS, University of Minnesota Medical Center, Minneapolis, MN, USA

8:45 AM

When Do We Call It Quits: Intervention Strategies and Outcomes for Medical Non-Adherence

Mary Amanda Dew, PhD, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

9:00 AM

Are All Substances Made Equal?

Andrea DiMartini, MD, University of Pittsburgh, Pittsburgh, PA, USA

9:15 AM

Case Presentation (Part 1): The Good, The Bad And The Ugly

Jay Baumwol, MBBS, FRACP, Fiona Stanley Hospital, Murdoch, Australia

**9:25 AM** _Q &A_

9:30 AM

Case Presentation (Part 2): The Good, The Bad And The Ugly

Gillian Coult, BSW, Alfred Hospital, Melbourne, Australia

**9:40 AM** _Q &A_

**9:45 AM** _Panel Discussion_

8:00 AM - 10:00 AM

## SYMPOSIUM 03: Primary Graft Dysfunction (PGD) and Vasoplegia After Heart Transplantation: Sink or Swim

Location:

Grand Hall B

Target Audience:

HTX, HF, MCS

**Chairs:**

Scott Silvestry, MD, and Hermann Reichenspurner, MD, PhD

**Session Summary:** The session goals are to review the existing and updated knowledge on primary graft dysfunction (PGD) and vasoplegia after heart transplantation. The presentations include: review of the published literature and ISHLT 2014 PGD definitions; the UK prospective PGD study; donor, recipient, and surgical risk factors; as well as experiences with post-transplant vasoplegia, with possible lessons learned from non-transplant heart surgery. There will be a 30-minute panel discussion at the end.

8:00 AM

Review of the Published Literature and the ISHLT 2014 PGD Definition

Jon A. Kobashigawa, MD, Cedars-Sinai Heart Institute, Los Angeles, CA, USA

8:15 AM

Review of Risk Factors for PGD: Donor, Recipient, and Surgical Procedure

Jennifer Cook, MD, University of Arizona, Tucson, AZ, USA

8:30 AM

First Prospective Observational Study on PGD: UK The Heart Evaluation and Retrieval for Transplantation Study

Andre R Simon, MD, PhD, Harefield Hospital, London, United Kingdom

8:45 AM

Vasoplegia after Adult Heart Transplantation and MCS Surgery

Maria M Patarroyo Aponte, MD, Allegheny General Hospital, Pittsburgh, PA, USA

9:00 AM

Severe PGD and Post-Operative Vasoplegia: Complications on the Same Spectrum or Different Entities?

Hiroo Takayama, MD, Columbia University, New York, NY, USA

9:15 AM

What Can We Learn from Non-Transplant Cardiac Surgery?

Paul J Mohacsi, MD, University Hospital, Bern, Switzerland

**9:30 AM** _Panel Discussion_

8:00 AM - 10:00 AM

## SYMPOSIUM 04: Thinking Outside the Box: Extra-Pulmonary Management in Lung Transplantation

Location:

Grand Hall C

Target Audience:

LTX, BSTR, ID, NHSAH, PATH, PEDS, PHARM, PH

**Chairs:**

Adrian C Lawrence, MD, and Helen Whitford, MBBS, FRACP

**Session Summary:** Gastrointestinal complications, extra-pulmonary factors or concurrent systemic disorders may compromise long-term outcome following lung transplantation. This session highlights new paradigms of disease understanding, diagnosis, treatment, prevention and possibilities for investigational trial design.

8:00 AM

Gastro-Intestinal Dysmotility in Thoracic Organ Transplantation Revisited: Importance, Evaluation, Treatment

Frank D'Ovidio, MD, Columbia University, New York, NY, USA

**8:20 AM** _Q &A_

8:24 AM

Gastro-Intestinal Malignancies in Thoracic Organ Transplantation: Collateral Damage?

Monique Malouf, MD, St. Vincent's Hospital, Sydney, Australia

**8:44 AM** _Q &A_

8:48 AM

New Lungs - Old Sinuses: Friends or Foes?

Joseph M. Pilewski, MD, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

**9:08 AM** _Q &A_

9:12 AM

Lung Transplantation in Systemic Disorders: Need for a Holistic Approach

Joseph P Lynch, MD, UCLA Medical Center, Los Angeles, CA, USA

**9:32 AM** _Q &A_

9:36 AM

Pregnancy After Thoracic Organ Transplantation: Unwanted But Unavoidable?

Mitesh Thakrar, MD, Alberta Lung Transplant Program, Calgary, AB, Canada

**9:56 AM** _Q &A_

8:00 AM - 10:00 AM

## SYMPOSIUM 05: Joint ISHLT/PHA Symposium: PH and Transplant: Where Do We Go From Here?

Location:

Grand Hall D

Target Audience:

PH, HF, HTX, LTX, MCS, NHSAH, PEDS

**Chairs:**

Oksana A. Shlobin, MD, and Karen Fagan, MD

**Session Summary:** Lung transplantation is a viable treatment option for Group I pulmonary arterial hypertension (PAH). In addition, the presence of a secondary forms of PH (Group 2, or 3) in patients who require heart or lung transplant confers a high risk of complications. This symposium, supported by a collaborative effort with the Pulmonary Hypertension Association (PHA), will address various aspects of lung transplantation in adult and pediatric patients with different forms of PH.

8:00 AM

Transplantation for PH in the Era of LAS

Roham Zamanian, MD, Stanford University, Stanford, CA, USA

**8:15 AM** _Q &A_

8:20 AM

Effect of Non-Group 1 Pulmonary Hypertension on Lung Transplantation

Jorn Carlsen, MD, DMSc, Copenhagen University Hospital, Copenhagen, Denmark

**8:35 AM** _Q &A_

8:40 AM

Saving the Lung: Liver Transplant in Portopulmonary Hypertension

Sonja Bartolome, MD, UT Southwestern Medical Center, Dallas, TX, USA

**8:55 AM** _Q &A_

9:00 AM

Oops: Pregnancy in Pulmonary Hypertension

Valerie McLaughlin, MD, University of Michigan, Ann Arbor, MI, USA

**9:15 AM** _Q &A_

9:20 AM

Challenging Choices: Switching between IV and Oral Prostanoid Therapy

Joel Wirth, MD, Maine Medical Center, Portland, ME, USA

**9:35 AM** _Q &A_

9:40 AM

Quality of Life is Most Important: Patient Related Outcomes in PH

Mardi Gomberg-Maitland, MD, Inova Heart and Vascular Institute, Falls Church, VA, USA

**9:55 AM** _Q &A_

8:00 AM - 10:00 AM

## SYMPOSIUM 06: The Failing Fontan - Where Do We Go From Here?

Location:

Seaport F-H

Target Audience:

PEDS, EEP, HF, HTX

**Chairs:**

Thomas Moller, MD, PhD, and Steven Kindel, MD

**Session Summary:** The aim is to discuss the care of the Fontan patient with heart failure across the spectrum, from pre-transplant medical management to mechanical support and heart transplantation. Timing of transplantation and listing, multi-organ transplantation and listing, and listing policies will all be discussed. Finally, a difficult case will be presented to the expert speaker panel at the end of the session.

8:00 AM

Sustainable Palliation: Optimizing Fontan Patients Prior to Heart Transplant

Jack Rychik, MD, Children's Hospital of Philadelphia, Philadelphia, PA, USA

**8:15 AM** _Q &A_

8:20 AM

Call for Help! Surgical Options for End-Stage Fontan Failure

Asif Hasan, MD, Freeman Hospital, Newcastle Upon Tyne, United Kingdom

**8:35 AM** _Q &A_

8:40 AM

Do You Want to List Too Early or Too Late? How to Determine When Fontan Patients Should be Listed for Transplant

Claire Irving, MBChB, MRCPCH, MD, Children's Hospital at Westmead, Sydney, Australia

**8:55 AM** _Q &A_

9:00 AM

It's Not JUST the Heart: Multi-Organ Transplantation in Fontan Patients

Daniel N Bernstein, MD, Stanford University, Stanford, CA, USA

**9:15 AM** _Q &A_

9:20 AM

Will Anybody Still Transplant My Patient? Programmatic Issues With Taking On Complex Fontan Patients

Richard Kirk, FRCP, FRCPCH, UT Southwestern Medical Center, Dallas, TX, USA

**9:35 AM** _Q &A_

9:40 AM

Case Presentation - The Failing Fontan Patient

Kathleen Simpson, MD, Washington University and Saint Louis Children's Hospital, St. Louis, MO, USA

**9:50 AM** _Panel Discussion_

8:00 AM - 10:00 AM

## SYMPOSIUM 07: Joint ISHLT/ESCMID Symposium: Ongoing Challenges in Transplant Infectious Diseases

Location:

Coronado A-C

Target Audience:

ID, HTX, LTX, MCS, PHARM

**Chairs:**

Lara Danziger-Isakov, MD, MPH, and Oriol Manuel, MD

**Session Summary:** This session, supported by a collaborative effort with the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), will provide important insight on relevant issues surrounding the care of thoracic organ transplant candidates and recipients and patients on mechanical circulatory support with infections.

8:00 AM

Non-Cultural Methods for Diagnosis and Prevention of Invasive Fungal Infections: Are We There Yet?

Barbara Alexander, MD, Duke University, Durham, NC, USA

**8:15 AM** _Q &A_

8:20 AM

Role of Inhaled Antimicrobials in the Era of Multidrug Resistance

Benoit Guery, MD, University Hospital Vaudois, Lausanne, Switzerland

**8:35 AM** _Q &A_

8:40 AM

Infection in Thoracic Organ Transplant Recipients on ECMO

Nicolas Mueller, MD, University Hospital Zurich, Zurich, Switzerland

**8:55 AM** _Q &A_

9:00 AM

Hepatitis C in Donor and Thoracic Organ Transplant Candidates and Recipients: A New Horizon

Paolo A Grossi, MD, PhD, University of Insubria, Varese, Italy

**9:15 AM** _Q &A_

9:20 AM

Experience in HIV Infection in Thoracic Organ Transplantation and MCS

Shirish Huprikar, MD, Mount Sinai Medical Center, New York, NY, USA

**9:35 AM** _Q &A_

9:40 AM

EBV and Anellovirus Viremia as Markers of Risk of Infection in Lung Transplant Recipients

José Maria Aguado, MD, Hospital 12 de Octubre, Madrid, Spain

**9:55 AM** _Q &A_

10:30 AM - 12:30 PM

## OPENING PLENARY SESSION

Location:

Seaport A-E

Target Audience:

ALL

**Chairs:**

Jeffrey J Teuteberg, MD, and Maryl R Johnson, MD

10:30 AM

Welcome/Program Chair Report

Jeffrey J Teuteberg, MD, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

10:35 AM

Thoracic Registry Report

Josef Stehlik, MD, MPH, University of Utah School of Medicine, Salt Lake City, UT, USA

10:55 AM

MCSD Registry Reports

James K Kirklin, MD, University of Alabama, Birmingham, AL, USA

11:05 AM

President's Report

Maryl R Johnson, MD, University of Wisconsin School of Medicine, Madison, WI, USA

**11:20 AM** ( **1)** The Treatment of Patients with Advanced Heart Failure Ineligible for Cardiac Transplantation with the HeartWare Ventricular Assist Device: Results of the ENDURANCE Supplement Trial; __ C. A. Milano1, J. G. Rogers1, A. J. Tatooles2, G. Bhat3, M. S. Slaughter4, E. J. Birks4, N. A. Mokadam5, C. Mahr5, J. S. Miller6, V. Jeevanandam7, K. Leadley8, K. D. Aaronson9, F. D. Pagani9. 1 _Duke University Medical Center, Durham, NC,_ 2 _Advocate Christ Medical Center, Downers Grove, IL,_ 3 _Advocate Health Care, Oak Lawn, IL,_ 4 _University of Louisville, Louisville, KY,_ 5 _University of Washington, Seattle, WA,_ 6 _Emory Healthcare, Atlanta, GA,_ 7 _University of Chicago, Chicago, IL,_ 8 _HeartWare, Framingham, MA,_ 9 _University of Michigan Medical Center, Ann Arbor, IL_

11:35 AM

Interactive Discussant

Vivek Rao, MD, PhD, Toronto General Hospital, Toronto, ON, Canada

**11:40 AM** ( **2)** The Impact of Age, Sex, Therapeutic Intent and Severity of Advanced Heart Failure on Outcomes in the Multicenter Study of Maglev Technology in Patients Undergoing Mechanical Circulatory Support Therapy with Heartmate 3 (Momentum 3) Pivotal Trial; __ D. Goldstein1, M. R. Mehra2, Y. Naka3, C. T. Salerno4, N. Uriel5, D. Dean6, A. Itoh7, F. D. Pagani8, E. R. Skipper9, G. Bhat10, N. Raval11, B. A. Bruckner12, J. Estep12, R. Cogswell13, C. A. Milano14, L. Fendelander15, J. B. O'Connell16, J. Cleveland17. 1 _Montefiore Medical Center, Bronx, NY,_ 2 _Brigham and Women's Hospital, Boston, MA,_ 3 _Columbia University Medical Center, New York, NY,_ 4 _St.Vincents Hospital, Indianapolis, IN,_ 5 _University of Chicago Medical Center, Chicago, IL,_ 6 _Piedmont Hospital, Atlanta, GA,_ 7 _Washington University School of Medicine, St.Louis, MO,_ 8 _University of Michigan Medical Center, Ann Arbor, MI,_ 9 _Carolinas Medical Center, Charlotte, NC,_ 10 _Advocate Christ Medical Center, Chicago, IL,_ 11 _Florida Hospital, Orlando, FL,_ 12 _Houston Methodist Hospital, Houston, TX,_ 13 _University of Minnesota Medical Center, Minneapolis, MN,_ 14 _Duke University Medical Center, Durham, NC,_ 15 _St.Jude Medical, Burlington, MA,_ 16 _St.Jude Medical, Pleasanton, CA,_ 17 _University of Colorado Medical Center, Denver, CO_

11:55 AM

Interactive Discussant

Jan D Schmitto, MD, PhD, MBA, Hannover Medical School, Hannover, Germany

12:00 PM

Pioneer Award Recipient Lecture: Standing on the Shoulders of Giants

Stuart W Jamieson, MB, FRCS, UC San Diego Health System, La Jolla, CA, USA

2:30 PM - 4:00 PM

## ORAL SESSION 01: Too Thick or Too Thin? Bleeding and Thrombosis in MCS

Location:

Seaport A-E

Target Audience:

MCS, HF, NHSAH, PHARM

**Chairs:**

Antonio Loforte, MD, and Nahush A. Mokadam, MD

**2:30 PM** ( **3)** Plasma Free Hemoglobin Activates Platelets and Protects Von Willebrand Factor from Degradation: Clinical and In Vitro Evidence That LVAD Hemolysis Causes LVAD Thrombosis; __ S. Hennessy-Strahs, D. Zhang, J. Kang, E. Krause, G. Redline, J. Howard, M. Acker, P. Atluri, C. Bermudez, C. R. Bartoli. _University of Pennsylvania, Philadelphia, PA, PA_

**2:45 PM** ( **4)** The Effect of Pre-Existing Hypercoagulable Disorders on Outcomes in Patients with LVADs; __ S. Adatya1, G. Egnaczyk2, J. N. Katz3, A. Brieke4, J. Stulak5, S. Nathan6, J. D. Rich7, S. Emani8, A. Kilic9, J. Ransom10, E. C. DePasquale11, D. Crandall12, D. J. Farrar12, K. Sundareswaran12, N. Uriel13. 1 _Advanced Heart Failure, Transplant and Mechanical Support, University of Chicago Medical Center, Chicago, IL,_ 2 _Christ Hospital, Cincinnati, OH,_ 3 _Division of Cardiology, University of North Carolina, Chapel Hill, NC,_ 4 _University of Colorado School of Medicine, Denver, CO,_ 5 _Division of Cardiovascular Surgery, Mayo Clinic, Rochester, MN,_ 6 _Memorial Hermann – Texas Medical Center, Houston, TX,_ 7 _Northwestern University Feinberg School of Medicine, Chicago, IL,_ 8 _Division of Cardiovascular Medicine, Ohio State University Medical Center, Columbus, OH,_ 9 _Division of Cardiac Surgery, Ohio State University Medical Center, Columbus, OH,_ 10 _Baptist Health Heart and Transplant Institute, Little Rock, AR,_ 11 _Ronald Reagan UCLA Medical Center, Los Angeles, CA,_ 12 _St. Jude Medical, Pleasanton, CA,_ 13 _University of Chicago Medical Center, Chicago, IL_

**3:00 PM** ( **5)** Standard Dose Doxycycline Does Not Alter von Willebrand Factor Degradation in Patients with CF LVAD; __ M. E. Keebler, N. Haglund, S. Zalawadiya, M. Djunaidi, G. Baxter, A. Shah, D. Gailani, J. Lindenfeld. _Vanderbilt University Medical Center, Nashville, TN_

**3:15 PM** ( **6)** Platelet Membrane-Related Morphologic Alterations: An Early Marker of Supra-Physiologic Shear-Mediated Platelet Activation Associated with VADs; __ A. Dimasi1, M. Rasponi1, F. Consolo1, A. Redaelli1, M. Slepian2. 1 _Politecnico di Milano, Milano, Italy,_ 2 _University of Arizona, Tucson, AZ_

**3:30 PM** ( **7)** Novel Analysis of High-Molecular-Weight Von Willebrand Factor Multimers Predicts Bleeding Events; __ S. Hennessy-Strahs, E. Bansal, J. Kang, E. Krause, M. Acker, P. Atluri, C. Bermudez, C. R. Bartoli. _University of Pennsylvania, Philadelphia, PA, PA_

**3:45 PM** ( **8)** Managing Anticoagulation in LVAD Patients: The Harefield Experience; __ R. Hards, G. Edwards, C. Kavanagh, M. Hedger, A. R. Simon. _Transplant and Mechanical Circulatory Support, Harefield Hospital, Uxbridge, United Kingdom_

2:30 PM - 4:00 PM

## ORAL SESSION 02: Engineering for Perfection in MCS

Location:

Grand Hall A

Target Audience:

MCS, HF, NHSAH

**Chairs:**

Shashank S Desai, MD, and Sanem Nalbantgil, MD

**2:30 PM** ( **9)** Mechano-Acoustic Detection of Dysfunction in Continuous Flow VADs Utilizing Stretchable Electronic Systems; __ Y. Liu1, K. R. Ammann2, J. A. Rogers1, M. J. Slepian2. 1 _University of Illinois, Urbana-Champaign, IL,_ 2 _University of Arizona, Tucson, AZ_

**2:45 PM** ( **10)** Virtual Implantation of the Infant Jarvik 2015 for Eligibility Criteria Establishment; __ J. R. Ryan1, J. Teal2, S. Pophal3, J. Nigro3, I. Adachi4, R. Jaquiss5, D. Frakes6, R. Jarvik2, T. Baldwin7. 1 _Cardiac 3D Print Lab, Phoenix Children's Hospital, Phoenix, AZ,_ 2 _Jarvik Heart, New York, NY,_ 3 _Phoenix Children's Hospital, Phoenix, AZ,_ 4 _Texas Children's Hospital, PhoenixHouston, TX,_ 5 _Duke University School of Medicine, Durham, NC,_ 6 _Arizona State University, Tempe, AZ,_ 7 _National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD_

**3:00 PM** ( **11)** A Novel, Implantable Device for Right-Side Mechanical Circulatory Support; __ J. R. Stanfield1, J. W. Long2. 1 _University of Utah, Oklahoma City, OK,_ 2 _INTEGRIS, Oklahoma City, OK_

**3:15 PM** ( **12)** Pulsatile Outflow in Cows Supported Long-Term with the BiVACOR Rotary TAH; __ W. E. Cohn1, F. Arabia2, D. L. Timms3, N. Greatrex3, M. Kleinheyer3, F. Nestler3, S. Diab1, O. Frazier1. 1 _Texas Heart Institute, Houston, TX,_ 2 _Cedars-Sinai Medical Center, Los Angeles, CA,_ 3 _BiVACOR Inc., Houston, TX_

**3:30 PM** ( **13)** Primary Biventricular Durable Ventricular Assist Devices from Experience North American Centers: A Cautionary Tale; __ P. Shah1, R. Ha2, R. Singh3, E. Adler4, M. Brambatti4, S. Kidambi2, D. Banerjee5, V. D. Pretorius6. 1 _Heart Failure and Transplantation, Inova Heart and Vascular Institute, Falls Church, VA,_ 2 _Cardiothoracic Surgery, Stanford University, Palo Alto, CA,_ 3 _Cardiac Surgery, Inova Heart and Vascular Institute, Falls Church, VA,_ 4 _Cardiovascular Medicine, University of California San Diego, La Jolla, CA,_ 5 _Cardiovascular Medicine, Stanford University, Palo Alto, CA,_ 6 _Cardiothoracic Surgery, University of California San Diego, La Jolla, CA_

**3:45 PM** ( **14)** Is ICD Implantation Necessary in Patients with Left Ventricular Assist Device Therapy?; __ A. Uribarri, S. V. Rojas, J. S. Hanke, M. Avsar, G. Dogan, E. Deniz, M. Ricklefs, A. Haverich, J. D. Schmitto. _Department of Cardiothoracic-, Transplantation- and Vascular Surgery, Hannover Medical School, Hannover, Germany_

2:30 PM - 4:00 PM

## ORAL SESSION 03: Moving DCD Forward: Thinking Inside the Box

Location:

Grand Hall B

Target Audience:

HTX, BSTR, MCS

**Chairs:**

Maryjane Farr, MD, and Kumud K Dhital, MD, PhD

**2:30 PM** ( **15)** 12 Hour Hypothermic Oxygenated Machine Perfusion Preserves the Quality of Donor Hearts: A Biomarker Analysis; __ S. G. Michel1, M. L. Madariaga2, S. M. Labbe3, E. Dupre3, L. M. Anderson4, K. Shanmugarajah5. 1 _Cardiac Surgery, Ludwig Maximilian University, Muenchen, Germany,_ 2 _Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA,_ 3 _IPS Therapeutique, Sherbrooke, QC, Canada,_ 4 _Paragonix Technologies, Inc., Braintree, MA,_ 5 _Nuffield Department of Surgery, University of Oxford, Oxford, United Kingdom_

**2:45 PM** ( **16)** Excellent Early Outcomes Following Heart Transplantation from Circulatory Dead Donors; __ S. Messer, A. Page, R. Axell, S. Colah, J. Hernandez-Sanchez, B. Parizkova, K. Valchanov, J. Dunning, J. Parameshwar, C. Lewis, Y. Abu Omar, S. Pettit, A. Kydd, D. Jenkins, C. Sudarshan, P. Catarino, M. Berman, M. Findlay, A. Ali, S. Tsui, S. R. Large. _Transplant Surgery, Papworth Hospital, Cambridgeshire, United Kingdom_

**3:00 PM** ( **17)** Rapid Retrieval and Ex Situ Portable Machine Perfusion Allows Successful Cardiac Transplantation with Donor Hearts from Controlled Donation After Circulatory Death; __ K. K. Dhital, M. Connellan, H. C. Chew, A. Iyer, C. Soto, A. Dinale, E. Granger, P. Jansz, C. Hayward, A. Jabbour, A. Keogh, E. Kotlyar, P. Spratt, P. Macdonald. _Cardiothoracic Surgery, St Vincent's Hospital, Sydney, NSW, Australia_

**3:15 PM** ( **18)** Donor Circulatory Death Heart Transplantation with Adverse Donor and Recipient Risk Profile; __ D. García Sáez, C. T. Bowles, O. K. Maunz, B. Zych, P. N. Mohite, O. Ananiadou, N. Marczin, A. Hurtado Doce, B. Raj, F. De Robertis, S. Rahman-Haley, N. R. Banner, A. R. Simon. _Cardiothoracic Transplantation and Mechanical Circulatory Support, Harefield Hospital NHS Trust, Harefield, London, United Kingdom_

**3:30 PM** ( **19)** Does the Assessment of DCD Donor Hearts on the Organ Care System Using Lactate Need Redefining?; __ A. Page, S. Messer, R. Axell, V. Naruka, S. Colah, S. Fakelman, C. Ellis, Y. Abu-Omar, A. Ali, M. Berman, P. Catarino, J. Dunning, D. Jenkins, C. Sudarshan, S. Tsui, S. Large. _Papworth Hospital NHS Foundation Trust, Cambridge, United Kingdom_

**3:45 PM** ( **20)** Midterm Follow up of Heart Transplantation with Routine Ex-Vivo Normothermic Preservation with Adverse Donor - Recipient Risk Profile; __ D. García Sáez, B. Zych, P. Mohite, F. De Robertis, C. T. Bowles, A. Sabashnikov, O. Ananiadou, B. Schmack, O. K. Maunz, A. Popov, T. Bahrami, N. R. Banner, A. R. Simon. _Cardiothoracic Transplantation and Mechanical Circulatory Support, Harefield Hospital NHS Trust, Harefield, London, United Kingdom_

2:30 PM - 4:00 PM

## ORAL SESSION 04: Donor Lung Allocation Strategies

Location:

Grand Hall C

Target Audience:

LTX, EEP, NHSAH

**Chairs:**

Dirk E Van Raemdonck, MD, and Laveena Chhatwani, MD

**2:30 PM** ( **21)** What Effect Does Rate of Change in LAS Have on Lung Transplant Outcomes?; __ A. Aretakis1, C. Towe2, M. Schecter2, D. L. Morales1, R. Bryant, III1, F. Zafar1. 1 _Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH,_ 2 _Pulmonology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH_

**2:45 PM** ( **22)** Lung Allocation Score Implementation Narrowed Racial/Ethnic Disparities in Adult Lung Transplantation Outcomes; __ B. Lim, J. Lasky, C. Schaufler, Y. Suzuki, D. Mallem, M. Molina, C. A. Bermudez, J. M. Diamond, J. D. Christie, E. Cantu. _University of Pennsylvania Perelman School of Medicine, Philadelphia, PA_

**3:00 PM** ( **23)** Objective Donor Scoring System for Lung Transplantation; __ W. M. Whited, J. R. Trivedi, V. H. van Berkel, M. P. Fox. _Department of Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, KY_

**3:15 PM** ( **24)** Is There a Rationale for an "Old-for-Old" Program in Lung Transplantation? A Comparative Study Using the International Society of Heart and Lung Transplantation Database; __ A. M. Bernhardt1, A. P. Levin2, J. Stehlik3, C. Benden4, L. Edwards5, F. M. Wagner1, H. Reichenspurner1. 1 _Department of Cardiovascular Surgery, Univ Heart Ctr Hamburg, Hamburg, Germany,_ 2 _Columbia University Medical Center, New York City, NY,_ 3 _University of Utah School of Medicine, Salt Lake City, UT,_ 4 _University Hospital Zurich, Zurich, Switzerland,_ 5 _United Network for Organ Sharing, Richmond, VA_

**3:30 PM** ( **25)** Are Donors with Pulmonary Arterial Embolism the Better Donors for Lung Transplantation?; __ W. Sommer1, H. Kirschner2, F. Ius1, J. Salman1, T. Siemeni1, M. Avsar1, C. Kuehn1, M. Kaufmann2, M. Greer3, J. Gottlieb3, A. Rahmel4, T. Welte3, A. Haverich1, I. Tudorache1, G. Warnecke1. 1 _Cardiothoracic Surgery, Hannover Medical School, Hannover, Germany,_ 2 _Deutsche Stiftung Organtransplantation, Region Nord, Germany,_ 3 _Respiratory Medicine, Hannover Medical School, Hannover, Germany,_ 4 _Deutsche Stiftung Organtransplantation, Frankfurt, Germany_

**3:45 PM** ( **26)** Use of Drug Intoxicated Donors for Lung Transplant: Impact on Survival Outcomes; __ W. M. Whited, J. R. Trivedi, M. P. Fox, V. H. van Berkel. _Department of Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, KY_

2:30 PM - 4:00 PM

## ORAL SESSION 05: Registries and Risk Scores in Pulmonary Hypertension: Updates, Lessons Learned, and Practice Changes

Location:

Grand Hall D

Target Audience:

PH, HF, HTX, LTX, NHSAH, PEDS, PHARM

**Chairs:**

Ioana R Preston, MD, and Tanya J. McWilliams, MD, PhD

**2:30 PM** ( **27)** Updated Risk Score Calculator for Pulmonary Arterial Hypertension Patients; __ R. L. Benza1, C. G. Elliott2, H. W. Farber3, A. J. Foreman4, A. E. Frost5, M. Gomberg-Maitland6, M. D. McGoon7, D. J. Pasta4, M. Selej8, R. P. Frantz7. 1 _Allegheny General Hospital, Pittsburgh, PA,_ 2 _Intermountain Medical Center and the University of Utah, Salt Lake City, UT,_ 3 _Boston University School of Medicine, Boston, MA,_ 4 _ICON Clinical Research, San Francisco, CA,_ 5 _Houston Methodist Lung Center, Weill-Cornell, Institute for Academic Medicine, Houston, TX,_ 6 _Inova Fairfax Hospital, Falls Church, VA,_ 7 _Mayo Clinic, Rochester, MN,_ 8 _Actelion Pharmaceuticals US, Inc., South San Francisco, CA_

**2:45 PM** ( **28)** Preliminary Data from the USA CTEPH Registry; __ K. M. Kerr1, W. R. Auger1, R. L. Benza2, R. N. Channick3, K. Chin4, R. D. Davis5, C. G. Elliott6, A. Z. LaCroix1, M. M. Madani1, V. V. McLaughlin7, M. H. Park8, V. F. Tapson9. 1 _Univ California San Diego, La Jolla, CA,_ 2 _University of Pittsburgh, Pittsburgh, PA,_ 3 _Massachusetts General Hospital, Boston, MA,_ 4 _University of Texas Southwestern, Dallas, TX,_ 5 _Florida Hospital, Orlando, FL,_ 6 _Intermountain Healthcare, Salt Lake City, UT,_ 7 _University of Michigan, Ann Arbor, MI,_ 8 _Houston Methodist Hospital, Houston, TX,_ 9 _Cedars-Sinai Medical Center, Los Angeles, CA_

**3:00 PM** ( **29)** REVEAL Risk Score in Patients with Chronic Thromboembolic Pulmonary Hypertension Receiving Riociguat; __ R. L. Benza1, H. W. Farber2, A. Frost3, E. Grünig4, M. Hoeper5, D. Busse6, C. Meier7, S. Nikkho8, H. Ghofrani9. 1 _Allegheny Gen Hosp, Pittsburgh, PA,_ 2 _Pulmonary Center, Boston University School of Medicine, Boston, MA,_ 3 _Houston Methodist Hospital Lung Center and Institute of Academic Medicine, Houston, TX,_ 4 _Centre for Pulmonary Hypertension, Thoraxclinic at the University Hospital Heidelberg, Heidelberg, Germany,_ 5 _Clinic for Respiratory Medicine, Hannover Medical School, Hannover, Germany,_ 6 _Chrestos Concept GmbH & Co, Essen, Germany, _7 _Global Medical Affairs, Bayer Pharma AG, Berlin, Germany,_ 8 _Global Clinical Development, Bayer Pharma AG, Berlin, Germany,_ 9 _University of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany, Member of the German Center, University Hospital Giessen and Marburg, Giessen, Germany_

**3:15 PM** ( **30)** OPUS Registry: Safety and Tolerability of Macitentan in a Real-World Setting; __ N. H. Kim1, M. Brand2, K. M. Chin3, R. N. Channick4, M. Selej5, V. V. McLaughlin6. 1 _University of California, San Diego, La Jolla, CA,_ 2 _Actelion Pharmaceuticals Ltd, Allschwil, Switzerland,_ 3 _UT Southwestern Medical Center, Dallas, TX,_ 4 _Massachusetts General Hospital, Boston, MA,_ 5 _Actelion Pharmaceuticals US Inc, South San Francisco, CA,_ 6 _University of Michigan, Ann Arbor, MI_

**3:30 PM** ( **31)** Orthotopic Heart Lung Transplantation Improving Outcomes Over Time; __ E. Nagy1, L. B. Edwards2, A. Y. Kucheryavaya3, J. Stehlik4, R. D. Yusen5, L. H. Lund1. 1 _Dept. of Cardiology, Karolinska University Hospital; Department of Medicine, Karolinska Institutet, Stockholm, Sweden,_ 2 _Research Department, United Network for Organ Sharing, Richmond, VA., International Society for Heart and Lung Transplantation Registry, Dallas, Texas., Dallas, TX,_ 3 _Research Department, United Network for Organ Sharing, Richmond, VA., International Society for Heart and Lung Transplantation Registry, Dallas, Texas, USA., Dallas, TX,_ 4 _University of Utah School of Medicine, Division of Cardiovascular Medicine, Salt Lake City, Utah, USA, Salt Lake City, UT,_ 5 _Divisions of Pulmonary and Critical Care Medicine and General Medical Sciences, Washington University School of Medicine, St. Louis, Missouri, USA., St. Loius, MO_

**3:45 PM** ( **32)** Orthotopic Heart-Lung Transplantation: Outcomes and Predictors of Outcomes in Recipients with Eisenmenger Syndrome, Other Congenital Etiologies, and Idiopathic Pulmonary Arterial Hypertension; __ E. Nagy1, L. B. Edwards2, A. Y. Kucheryavaya2, J. Stehlik3, R. D. Yusen4, L. H. Lund1. 1 _Department of Cardiology, Karolinska University Hospital, Department of Medicine, Karolinska Institutet, Stockholm, Sweden,_ 2 _Research Department, United Network for Organ Sharing, Richmond, VA, USA., International Society for Heart and Lung Transplantation Registry, Dallas, Texas, USA, Dallas, TX,_ 3 _University of Utah School of Medicine, Division of Cardiovascular Medicine, Salt Lake City, Utah, USA., Salt Lake City, UT,_ 4 _Divisions of Pulmonary and Critical Care Medicine and General Medical Sciences, Washington University School of Medicine, St. Louis, Missouri, USA., St. Louis, MO_

2:30 PM - 4:00 PM

## ORAL SESSION 06: Pediatric Heart Failure: Diagnosis, Management, and Confronting Risk

Location:

Seaport F-H

Target Audience:

PEDS, HF, HTX

**Chairs:**

Ashwin K Lal, MD, and Shigetoyo Kogaki, MD

**2:30 PM** ( **33)** Distinct Disease Mechanisms Govern the Progression of Pediatric and Adult Dilated Cardiomyopathy; __ M. Patel1, C. Schneider2, J. Mohan2, C. Canter1, T. Jeffrey3, K. J. Lavine2. 1 _Pediatrics, Washington University, St Louis, MO,_ 2 _Cardiology, Washington University, St Louis, MO,_ 3 _Pediatrics, University of Tennessee Health Center, Memphis, TN_

**2:45 PM** ( **34)** Diagnostic Errors at First Presentation of Heart Failure in Children; __ K. Puri1, H. Singh2, S. W. Denfield1, A. G. Cabrera1, W. J. Dreyer1, J. F. Price1. 1 _Cardiology, Baylor College of Medicine/Texas Children's Hospital, Houston, TX,_ 2 _Medicine Health Services Research, Baylor College of Medicine, Houston, TX_

**3:00 PM** ( **35)** Hemodynamics of the Pediatric Failing Fontan; __ J. C. Dykes1, D. B. McElhinney2, D. Bernstein1, M. R. Chrisant3, S. Chen1, K. P. Daly4, R. K. Ameduri5, K. R. Knecht6, M. E. Richmond7, K. Y. Lin8, S. Urschel9, J. Simmonds10, K. E. Simpson11, C. S. Almond1, S. Chen1. 1 _Pediatrics, Stanford University, Palo Alto, CA,_ 2 _Cardiothoracic Surgery, Stanford University, Palo Alto, CA,_ 3 _Pediatrics, Joe DiMaggio Children's Hospital, Fort Lauderdale, FL,_ 4 _Pediatrics, Harvard University, Boston, MA,_ 5 _Pediatrics, University of Minnesota, Minneapolis, MN,_ 6 _Pediatrics, University of Arkansas for Medical Sciences, Arkansas, AR,_ 7 _Pediatrics, Columbia University Medical Center, New York, NY,_ 8 _Pediatrics, University of Pennsylvania, Philadelphia, PA,_ 9 _Pediatrics, University of Alberta, Edmonton, AB, Canada,_ 10 _Pediatrics, Great Ormond Street Hospital, London, United Kingdom,_ 11 _Pediatrics, Washington University School of Medicine, St. Louis, MO_

**3:15 PM** ( **36)** Assist Device Therapy for Myocarditis - Analysis from the German Multi-Centre Prospective Myocarditis Registry in Pediatric Patients: "Mykke"; __ S. Schubert1, F. Degener2, B. Opgen-Rhein3, F. Schmidt4, A. Weigelt5, R. Wagner6, T. Mir7, A. Rentzsch8, E. z. Knyphausen9, K. Papkostas10, G. Wiegand11, B. Ruf12, T. Hannes13, K. Reineker14, D. Kiski15, M. Khalil16, M. Steinmetz17, G. Fischer18, T. Pickardt19, D. Messroghli20, O. O. MYKKE Consortium21. 1 _Congenital Heart Disease/Pediatric Cardiology, Deutsches Herzzentrum Berlin and DZHK, Berlin, Germany,_ 2 _Congenital Heart Disease/Pediatric Cardiology, Deutsches Herzzentrum Berlin, Berlin, Germany,_ 3 _Pediatric Cardiology, Charité Universitätsmedizin Berlin, Berlin, Germany,_ 4 _Pediatric Cardiology, Medizinische Hochschule Hannover, Hannover, Germany,_ 5 _Pediatric Cardiology, Universitätsklinikum Erlangen, Erlangen, Germany,_ 6 _Pediatric Cardiology, Herzzentrum Leipzig, Leipzig, Germany,_ 7 _Pediatric Cardiology, Universitäres Herzzentrum Hamburg, Hamburg, Germany,_ 8 _Pediatric Cardiology, Universitätsklinikum des Saarlandes, Homburg, Germany,_ 9 _Congenital Heart Disease, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany,_ 10 _Structural Heart Disease/Pediatric Cardiology, Klinikum Links der Weser, Bremen, Germany,_ 11 _Pediatric Cardiology, Universitätsklinikum Tübingen, Tübingen, Germany,_ 12 _Congenital Heart Disease/Pediatric Cardiology, 12Deutsches Herzzentrum und Technische Universität München, München, Germany,_ 13 _Pediatric Cardiology, Uniklinik Köln, Cologne, Germany,_ 14 _Congenital Heart Disease/Pediatric Cardiology, Universitäts-Herzzentrum Freiburg Bad Krozingen, Freiburg, Germany,_ 15 _Pediatric Cardiology, Universitätsklinikum Münster, Münster, Germany,_ 16 _Pediatric Cardiology, Universitätsklinik Gießen, Giessen, Germany,_ 17 _Pediatric Cardiology and Intensive Care, Universitätsmedizin und Kinderherzklinik Göttingen, Göttingen, Germany,_ 18 _Clinic for Pediatric Cardiology, Universitätsklinikum Schleswig-Holstein, Kiel, Germany,_ 19 _Kompetenznetz für angeborene Herzfehler, Berlin, Germany,_ 20 _Cardiology, Deutsches Herzzentrum Berlin & DZHK, Berlin, Germany, _21 _Multicenter, Germany, Germany_

**3:30 PM** ( **37)** Renal Dysfunction as a Relative Contraindication to Pediatric Heart Transplantation; __ I. Wilmot, R. Rizwan, F. Zafar, D. Hooper, T. D. Ryan, C. Chin. _Cardiology, Cincinnati Children's Hospital All Children 's Hospital, Cincinnati, OH_

**3:45 PM** ( **38)** The Impact of Tracheostomy on Pediatric Heart Transplant Outcomes: A Multi-Institutional Analysis; __ J. A. Spinner1, S. W. Denfield1, K. Puri1, S. A. Morris1, B. S. Moffett2, J. F. Price1, W. J. Dreyer1, A. G. Cabrera1. 1 _Pediatrics, Baylor College of Medicine, Houston, TX,_ 2 _Pain Medicine, Texas Children's Hospital, Houston, TX_

2:30 PM - 4:00 PM

## ORAL SESSION 07: Cutting Edge Updates in Infectious Diseases

Location:

Coronado A-C

Target Audience:

ID, ALL

**Chairs:**

Karen Doucette, MD, MSc, and Stephanie M Pouch, MD

**2:30 PM** ( **39)** Clinical Risk Factors for Invasive Aspergillosis in Lung Transplant Recipients: Results of an International Cohort Study; __ C. Aguilar1, B. Hamandi2, C. Fegbeutel3, F. P. Silveira4, E. A. Verschuuren5, P. Ussetti6, P. V. Chin-Hong7, A. Sole8, C. Holmes-Liew9, E. M. Billaud10, P. A. Grossi11, O. Manuel12, D. J. Levine13, R. G. Barbers14, D. Hadjiliadis15, L. Singer16, S. Husain1. 1 _Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada,_ 2 _Department of Pharmacy, University Health Network, Toronto, ON, Canada,_ 3 _Hannover Medical School, Hannover, Germany,_ 4 _University of Pittsburgh, Pittsburgh, PA,_ 5 _University Medical Center Groningen, University of Groningen, Groningen, Netherlands,_ 6 _Hospital Puerta de Hierro, Madrid, Spain, Madrid, Spain,_ 7 _University of California, San Francisco, San Francisco, CA,_ 8 _University and Polytechnic Hospital La Fe, Universidad de Valencia, Valencia, Spain,_ 9 _Royal Adelaide Hospital, Adelaide, Australia,_ 10 _APHP Hopital Européen G Pompidou, Paris, France,_ 11 _University of Insubria, Varese, Italy,_ 12 _University Hospital of Lausanne, Lausanne, Switzerland,_ 13 _University of Texas Health Science Center San Antonio, San Antonio, TX,_ 14 _KECK Medical Center of University of Southern California, Los Angeles, CA,_ 15 _University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, PA,_ 16 _Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada_

**2:45 PM** ( **40)** Aspergillus Galactomannan Detection in Exhaled Breath Condensate for the Diagnosis of Invasive Aspergillosis in Lung Transplant Recipients; __ A. Bhimji1, A. Bhaskaran1, L. G. Singer2, D. Kumar1, A. Humar1, R. Pavan1, C. Rotstein1, S. Keshavjee2, T. Mazzulli3, S. Husain1. 1 _Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada,_ 2 _Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada,_ 3 _Mount Sinai Hospital, Toronto, ON, Canada_

**3:00 PM** ( **41)** Impact of Cytomegalovirus and Its Prevention Strategies on Survival in Thoracic Transplant Recipients; __ J. K. Preiksaitis, C. A. Mabilangan, C. Cervera. _Medicine, University of Alberta, Edmonton, AB, Canada_

**3:15 PM** ( **42)** Invasive Mycobacterium abscessus Infection in Heart Transplant Recipients; __ E. K. Maziarz1, A. W. Baker1, C. B. Patel2, P. Patel2, C. A. Milano3, J. N. Schroder3, M. A. Daneshmand3, B. D. Alexander1, C. R. Wolfe1. 1 _Division of Infectious Diseases and International Health, Duke University, Durham, NC,_ 2 _Division of Cardiology, Duke University, Durham, NC,_ 3 _Division of Cardiovascular and Thoracic Surgery, Duke University, Durham, NC_

**3:30 PM** ( **43)** Clinical and Microbiologic Characteristics of Infections in Left Ventricular Assist Device Recipients; __ M. Bradbury1, S. Phillips1, J. Stulak2, K. Abdullah1, C. T. Salerno3, S. Maltais2, S. M. Dunlay2, T. F. Dardas4, K. Aaronson5, F. D. Pagani5, J. A. Cowger3, P. Shah1. 1 _Inova Heart and Vascular Institute, Falls Church, VA,_ 2 _Mayo Clinic, Rochester, MN,_ 3 _St. Vincent Heart Center of Indiana, Indianapolis, IN,_ 4 _University of Washington, Seattle, WA,_ 5 _University of Michigan Health System, Ann Arbor, MI_

**3:45 PM** ( **44)** Potential Posaconazole Sequestration During Extracorporeal Membrane Oxygentation: Results from an Ex-Vivo Experiment; __ H. Lyster1, T. Pitt1, O. Maunz1, D. Garcia Saez1, J. Tiller1, N. Leaver1, J. Roberts2, K. Shekar3, D. Brown4, J. Mills4, M. Carby1, A. Simon1, A. Reed1. 1 _Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom, _2 _The University of Queensland, Brisbane, Australia,_ 3 _The Prince Charles Hospital, Brisbane, Australia,_ 4 _University of Portsmouth, Portsmouth, United Kingdom_

4:30 PM - 6:00 PM

## ORAL SESSION 08: Bugs and Devices: A Bad Combination

Location:

Seaport A-E

Target Audience:

MCS, ID, NHSAH, PHARM

**Chairs:**

Simon Maltais, MD, PhD, and Orla Morrissey, MD

**4:30 PM** ( **45)** Epidemiology of Bloodstream Infections in MCSD Recipients in the IMACS Registry; __ S. Aslam1, R. Xie2, V. Chu3, J. Cowger4, S. Schueler5, T. de By6, K. Gould5, O. Morrissey7, L. Lund8, S. Martin9, D. Goldstein10, M. Hannan11. 1 _Univ. of CA, San Diego, San Diego, CA,_ 2 _Univ. of Alabama, Birmingham, AL,_ 3 _Duke University, Durham, NC,_ 4 _St Vincent Heart Center of Indiana, Indianopolis, IN,_ 5 _Freeman Hospital, Newcastle upon Tyne, United Kingdom,_ 6 _Euromacs, Berlin, Germany,_ 7 _Alfred Hospital, Melbourne, Australia,_ 8 _Karolinska Institute, Stockholm, Sweden,_ 9 _Geisinger Health System, Danville, PA,_ 10 _Montefiore Medical Center, New York, NY,_ 11 _Mater Misericordiae University Hospital, Dublin, Ireland_

**4:45 PM** ( **46)** The Epidemiology of Infection in MCS from the IMACS Database: January 2013 to December 2015; __ M. M. Hannan1, R. Xie2, J. A. Cowger3, S. Schueler4, T. M. de By5, A. I. Dipchand6, V. H. Chu7, R. S. Cantor2, C. Koval8, T. Krabatsch9, C. Hayward10, J. K. Kirklin2. 1 _Mater Misericordiae University Hospital, University College Dublin, Dublin, Ireland,_ 2 _The James and John Kirklin Institute for Research in Surgical Outcomes (KIRSO), UAB, Birmingham, AL,_ 3 _St Vincent Heart Center of Indiana, Indianapolis, IN,_ 4 _Newcastle Freeman Hospital, UK, Newcastle, United Kingdom,_ 5 _EUROMACS, Berlin, Germany,_ 6 _Hospital for Sick Children, Toronto, ON, Canada,_ 7 _Division of Infectious Diseases, Duke University Medical Center, Durham, NC,_ 8 _Cleveland Clinic, Cleveland, OH,_ 9 _Deutsches Herzzentrum, Berlin, Germany,_ 10 _St Vincent's Hospital, Sydney, Australia_

**5:00 PM** ( **47)** Epidemiology of Fungal Infections (FI) in Mechanical Circulatory Support Device (MCSD) Recipients: Analysis of IMACS Registry 2013-2015; __ O. Morrissey1, R. Xie2, J. Schaenman3, S. Husain4, M. Mooney5, T. Nakatani6, R. Kormos7, M. Gómez-Bueno8, S. Aslam9, Y. Pya10, M. Hannan11. 1 _Infectious Diseases, Alfred Health, Melbourne, Australia,_ 2 _The James and John Kirklin Institute for Research in Surgical Outcomes (KIRSO/UAB), Birmingham, AL,_ 3 _Medicine, University of California, Los Angeles, Los Angeles, CA,_ 4 _Infectious Diseases, University Health Network, Toronto, ON, Canada,_ 5 _Sentara Norfolk Transplant Center/EVMS, Norfolk, VA,_ 6 _Maki Hospital, Osaka, Japan,_ 7 _Surgery, University of Pittsburgh, Pittsburgh, PA,_ 8 _Cardiology, Hospital Univ. Puerta de Hierro. Majadahonda, Madrid, Spain,_ 9 _Infectious Diseases, University of California, San Diego, San Diego, CA,_ 10 _National Research Cardiac Surgery Center, Astana, Kazakhstan,_ 11 _Microbiology, Mater Misericordiae University Hospital, Dublin, Ireland_

**5:15 PM** ( **48)** Risk Factors and Mortality for Sepsis in Left Ventricular Assist Device Recipients; __ P. S. Joy1, G. Kumar2, J. K. Bhama1, L. M. Cadaret1. 1 _University of Iowa, Iowa City, IA,_ 2 _Northeast Georgia Health System, Gainesville, GA_

**5:30 PM** ( **49)** Supporting Imaging Modalities for Improving Diagnosis of Infection in Patients on CF-LVAD:A Single-Center Experience Including 61 Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomographies; __ A. M. Dell'Aquila1, N. Avramovic2, A. Motekallemi1, M. Scherer1, J. R. Sindermann1, C. Wenning1. 1 _Department of Thoracic and Cardiovascular Surgery, University Hospital Münster, Münster, Germany,_ 2 _Department of Nuclear Medicine, University Hospital Münster, Münster, Germany_

**5:45 PM** ( **50)** Hepatitis C Virus Infection Does Not Impact Survival Following Continuous-Flow Left Ventricular Assist Device Implantation; __ A. Pendyal, J. M. Gelow. _Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR_

4:30 PM - 6:00 PM

## ORAL SESSION 09: MCS Surgery: Does Nuance Make a Master?

Location:

Grand Hall A

Target Audience:

MCS, HF, NHSAH

**Chairs:**

Nader Moazami, MD, and Diyar Saeed, MD

**4:30 PM** ( **51)** A Novel Technique of Temporary Right Ventricular Assist Device (RVAD) Placement During Durable Left Ventricular Assist Device (LVAD) Implant to Allow Early Ambulation and Bedside Percutaneous Removal; __ G. Zanotti1, T. B. Reece1, D. Fullerton1, J. Cleveland1, A. Babu2. 1 _Cardiothoracic Surgery, University of Colorado, Aurora, CO,_ 2 _Cardiothoracic Surgery, ST. Thomas Hospital, Nashville, TN_

**4:45 PM** ( **52)** Pre-Implant Left Ventricular Apex Position Predicts Risk of HeartMate II Pump Thrombosis; __ L. T. Yarboro, R. B. Hawkins, J. Mehaffey, G. Ailawadi, I. L. Kron, J. A. Kern, R. K. Ghanta. _University of Virginia, Charlottesville, VA_

**5:00 PM** ( **53)** Surgical Strategy to Support Right Ventricle with HVAD RVAD: Right Atrial vs Right Ventricular Diaphragmatic Surface Cannulation; __ Y. Shudo, R. V. Ha, O. Reinhartz, J. Woo, J. Boyd, C. Almond, D. N. Rosenthal, S. Chen, K. Maeda. _Stanford University, Stanford, CA_

**5:15 PM** ( **54)** Should Prophylactic Tricuspid Valve Surgery Be Considered in Patients with Atrial Fibrillation Undergoing LVAD Implantation?; __ S. Maltais1, V. Tchantchaleishvili1, R. C. Daly1, D. L. Joyce1, L. D. Joyce1, S. S. Kushwaha2, J. M. Stulak1. 1 _Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN,_ 2 _Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN_

**5:30 PM** ( **55)** Outcomes of Multiple Concomitant Valve Procedures in Patients Receiving Continuous-Flow Left Ventricular Assist Device; __ J. Han1, H. Takayama1, P. A. Kurlansky1, A. R. Garan2, M. Yuzefpolskaya2, V. K. Topkara2, P. C. Colombo2, Y. Naka1, K. Takeda1. 1 _Division of Cardiothoracic Surgery, Columbia University Medical Center, New York, NY,_ 2 _Division of Cardiology, Columbia University Medical Center, New York, NY_

**5:45 PM** ( **56)** First-in-Human (FIH) Experience with the Intravascular Ventricular Assist System iVAS a Novel Approach to Mechanical Circulatory Support; __ V. Jeevanandam1, D. Onsager1, T. Song1, T. Ota1, C. Juricek1, T. Lammy1, V. Kagan1, H. Costantini1, G. Sayer2, S. Adatya2, G. Kim2, N. Uriel2. 1 _CT Surgery, University of Chicago, Chicago, IL,_ 2 _Cardiology, University of Chicago, Chicago, IL_

4:30 PM - 6:00 PM

## ORAL SESSION 10: Movement on the Heart Transplant Wait List: VADS, Exceptions and Antibodies

Location:

Grand Hall B

Target Audience:

HTX, EEP, MCS, NHSAH

**Chairs:**

Mark J Zucker, MD, and Tahir Yagdi, MD

**4:30 PM** ( **57)** Trends in 1A Listing Exceptions in Heart Transplant (HT) Recipients Bridged by Left Ventricular Assist Device (LVAD) Type; __ A. Salimbangon1, J. A. Cowger2, D. Vucicevic1, L. Honoris1, A. Iyengar1, S. Shah1, E. Moreno1, A. Chang1, L. Reardon1, K. Pandya3, M. C. Deng1, A. Ardehali1, E. C. DePasquale1. 1 _UCLA, Los Angeles, CA,_ 2 _St Vincent Heart Center, Indianapolis, IN,_ 3 _UC Davis, Sacramento, CA_

**4:45 PM** ( **58)** Left Ventricular Assist Device Is Protective Against Cardiac Transplant Delisting for Medical Unsuitability ; __ R. Cogswell1, S. Duval1, J. Schultz1, C. Martin1, K. Liao2, R. John2. 1 _Cardiology, University of Minnesota, Minneapolis, MN,_ 2 _Cardiothoracic Surgery, University of Minnesota, Minneapolis, MN_

**5:00 PM** ( **59)** Age Dependent Risk of LVAD Used as a Bridge to Transplant and of Comorbidities on Post-Transplant Survival: An Analysis of ISHLT Registry; __ M. Masetti1, A. R. Wilk2, F. Grigioni1, A. Russo1, L. B. Edwards2, L. H. Lund3, J. Stehlik4, L. Potena1. 1 _Heart Transplant Program, DIMEC, S.Orsola Hospital, University of Bologna, Bologna, Italy,_ 2 _United Network for Organ Sharing, Richmond, VA,_ 3 _Karolinska Institutet, Department of Medicine, and Karolinska University Hospital, Department of Cardiology, Stockholm, Sweden,_ 4 _Utah Transplant Affiliated Hospitals (U.T.A.H.) Cardiac Transplant Program, University of Utah School of Medicine, Salt Lake City, UT_

**5:15 PM** ( **60)** Impact of Sensitization and 4S Prioritization on Heart Transplantation Waiting Times in Canada; __ N. Aleksova1, H. J. Ross2, L. M. Mielniczuk1, R. A. Davies1, E. Stadnick1, S. Chih1. 1 _University of Ottawa Heart Institute, Ottawa, ON, Canada,_ 2 _University Health Network, Toronto, ON, Canada_

**5:30 PM** ( **61)** Revealing a New Mode of Sensitization Induced by Mechanical Circulatory Support Devices (MCS): Impact of Anti-AT1R Antibodies; __ X. Zhang1, J. Mirocha2, T. Aintablian3, J. Moriguchi4, F. Arabia5, J. A. Kobashigawa4, N. L. Reinsmoen1. 1 _HLA and Immunogenetcis Laboratory, Cedars-Sinai Health System, Los Angeles, CA,_ 2 _Biostastic Core, Cedars-Sinai Health System, Los Angeles, CA,_ 3 _California Heart Center, Los Angeles, CA,_ 4 _Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA,_ 5 _Cardiovascular Surgery, Cedar Sinai Medical Center, Los Angeles, CA_

**5:45 PM** ( **62)** Trends in 1A Listing Exceptions in Heart Transplant (HT) Recipients Bridged with Mechanical Circulatory Support (MCS); __ E. C. DePasquale1, J. A. Cowger2, L. Honoris1, D. Vucicevic1, S. Shah1, A. Iyengar1, A. Salimbangon1, E. Moreno1, A. Chang1, L. Reardon1, K. Pandya3, M. Deng1, A. Ardehali1. 1 _UCLA, Los Angeles, CA,_ 2 _St Vincent Heart Center, Indianapolis, IN,_ 3 _UC Davis, Sacramento, CA_

4:30 PM - 6:00 PM

## ORAL SESSION 11: Improving Prognosis in Chronic Lung Allograft Dysfunction

Location:

Grand Hall C

Target Audience:

LTX, BSTR, EEP, ID, NHSAH, PATH, PHARM

**Chairs:**

Ramsey R Hachem, MD, and Erika D Lease, MD

**4:30 PM** ( **63)** Correlation Between Microbial Diversity, Lung Inflammation, and Chronic Lung Allograft Dysfunction; __ L. Levy1, A. Tigert2, T. Saito3, K. Boonstra2, J. Prescod4, D. Hwang2, S. Keshavjee2, S. Juvet2, B. Coburn4, T. Martinu2. 1 _Toronto Lung Transplant Program, Toronto, ON, Canada,_ 2 _Toronto General Hospital, University Health Network, Toronto, ON, Canada,_ 3 _Kansai Medical University, Hirakara, Japan,_ 4 _Toronto General Research Institute, Toronto, ON, Canada_

**4:45 PM** ( **64)** Lung Bile Acid Correlation with Inflammation, Infection, CLAD and Survival; __ M. Ahmed1, R. Zamel2, D. Nakajima2, W. Klement3, M. Cypel2, J. Todd4, S. Weigt5, M. Liu2, L. Singer1, S. Keshavjee2, T. Martinu1. 1 _Medicine, Toronto Lung Transplant Program, Toronto, ON, Canada,_ 2 _Thoracic Surgery, Toronto Lung Transplant Program, Toronto, ON, Canada,_ 3 _Toronto Lung Transplant Program, Toronto, ON, Canada,_ 4 _Medicine, Duke University, Durham, NC,_ 5 _Medicine, UCLA, Los Angeles, CA_

**5:00 PM** ( **65)** Matrix Metalloproteinase-7 May Be a Biomarker of Early Chronic Lung Rejection; __ J. Jaffar1, T. Phan1, M. Stewart2, B. Levey2, M. Paraskeva2, G. Snell2, G. Westall1. 1 _The Alfred Hospital/Monash University, Melbourne, Australia,_ 2 _The Alfred Hospital, Melbourne, Australia_

**5:15 PM** ( **66)** The Impact of De Novo Donor-Specific Antibodies on Bronchiolitis Obliterans Syndrome and Restrictive Allograft Syndrome; __ E. Miyamoto, T. Martinu, W. Klement, S. Juvet, S. Keshavjee, K. Tinckam, J. Tikkanen. _Toronto Lung Transplant Program, University of Toronto, Toronto, ON, Canada_

**5:30 PM** ( **67)** Role of Complement-Binding Anti-HLA Antibodies Detection as Early Predictor of Chronic Lung Dysfunction After Lung Transplantation; __ O. Brugière1, A. Roux2, J. Le Pavec3, D. Sroussi1, F. Parquin2, P. Pradère3, C. Dupin1, V. Bunel1, G. Mourin1, G. Jebrak1, G. Thabut1, G. Dauriat1, Y. Castier1, P. Mordant1, B. Lortat Jacob1, S. Jean-Baptiste1, H. Mal1, C. Suberbielle1, J. Taupin1. 1 _Hôpital Bichat, Paris, France,_ 2 _Hôpital Foch, Suresnes, France,_ 3 _Hôpital Marie Lannelongue, Le Plessis Robinson, France_

**5:45 PM** ( **68)** Immunophenotyping Pre Total Lymphoid Irradiation for BOS After Lung Transplantation May Predict Response to Therapy; __ B. Schmack1, F. Cano Romero2, J. Hester2, V. Durrant3, S. Soresi4, D. Garcia Saez1, B. Zych1, O. Ananiadou1, A. R. Simon1, M. Carby4, A. Reed4, J. Smith3. 1 _Department of Cardiothoracic Transplantation & Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, Harefield, United Kingdom, _2 _Nuffield Department of Surgical Science, University of Oxford, Oxford, United Kingdom,_ 3 _Tissue Typing Service, Royal Brompton and Harefield NHS Foundation Trust, Harefield, United Kingdom,_ 4 _Department of Respiratory and Transplant Medicine, Royal Brompton and Harefield NHS Foundation Trust, Harefield, United Kingdom_

4:30 PM - 6:00 PM

## ORAL SESSION 12: Innovation in Pediatric MCS

Location:

Seaport F-H

Target Audience:

PEDS, MCS

**Chairs:**

Kristine J Guleserian, MD, and Oliver Miera, MD

**4:30 PM** ( **69)** Reverse Remodeling After Placement of Pulsatile and Continuous Flow Left Ventricular Assist Device in Children with End-Stage Idiopathic Dilated Cardiomyopathy; __ J. Kasten1, P. Punjwani2, S. Zhang3, D. Rakheja1, B. B. Das2. 1 _Department of Pathology, UT Southwestern Med Ctr, Dallas, TX,_ 2 _Division of Pediatric Cardiology, UT Southwestern Med Ctr, Dallas, TX,_ 3 _Department of Clinical Science Research, UT Southwestern Med Ctr, Dallas, TX_

**4:45 PM** ( **70)** Are Implantable Cardioverter-Defibrillators Indicated in Pediatric Ventricular Assist Device Patients?; __ A. Bulic, S. Ceresnak, J. C. Dykes, S. Chen, K. Motonaga, D. N. Rosenthal, C. S. Almond, B. D. Kaufman, S. A. Hollander, K. Maeda, N. A. Laroussi, D. Hanisch, A. V. Trela, J. M. Murray, A. M. Dubin. _Division of Pediatric Cardiology, Stanford University, Palo Alto, CA_

**5:00 PM** ( **71)** Post-Transplant Outcomes in Pediatric VAD Patients: A Pedimacs-PHTS Linkage Study; __ D. L. Sutcliffe1, E. Pruitt2, R. S. Cantor2, J. Godown3, J. Lane4, M. W. Turrentine5, S. P. Law6, J. L. Lantz7, D. C. Naftel2, J. K. Kirklin2, D. Bernstein8, E. D. Blume9. 1 _Pediatric Cardiology, Children's Health Dallas, UT Southwestern, Dallas, TX,_ 2 _Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL,_ 3 _Pediatric Cardiology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN,_ 4 _Pediatric Critical Care, Phoenix Children's Hospital, Phoenix, AZ,_ 5 _Cardiac Surgery, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN,_ 6 _Pediatric Cardiology, Columbia University-Morgan Stanley Children's Hospital of New York Presbyterian, New York, NY,_ 7 _Pediatric Cardiology, Children's Health Dallas, Dallas, TX,_ 8 _Pediatric Cardiology, Lucile Packard Children's Hospital at Stanford, Palo Alto, CA,_ 9 _Cardiology, Boston Children's Hospital, Harvard Medical School, Boston, MA_

**5:15 PM** ( **72)** In Vitro Examination of the VentriFlo™ True Pulse Pump for Failing Fontan Support; __ P. M. Trusty1, M. Tree2, D. Vincent3, J. P. Naber3, K. Maher4, A. P. Yoganathan1, S. Deshpande4. 1 _BME, Georgia Institute of Technology, Atlanta, GA,_ 2 _ME, Georgia Institute of Technology, Atlanta, GA,_ 3 _Design Mentor, Pelham, NH,_ 4 _Department of Pediatrics, Emory University School of Medicine, Atlanta, GA_

**5:30 PM** ( **73)** Outcome of a Continous Flow Pump (Jarvik 2000) as Bridge to Transplantation or Destination Therapy in Pediatric Patients; __ G. Perri1, S. Filippelli1, G. Testa1, F. Iodice1, R. Adorisio1, R. Iacobelli1, A. Di Molfetta1, M. Massetti2, A. Amodeo1. 1 _Bambino Gesù Children Hospital, Rome, Italy,_ 2 _Catholic University of Sacred Heart, Rome, Italy_

**5:45 PM** ( **74)** Compassionate Deactivation of Ventricular Assist Devices in Children: A Survey of Pediatric VAD Clinicians' Perspectives and Practices; __ B. D. Kaufman1, S. A. Hollander1, S. H. Chen1, D. Bernstein1, D. N. Rosenthal1, C. Almond1, J. M. Murray1, A. M. Burgart2, H. J. Cohen1, J. N. Kirkpatrick3, E. D. Blume4. 1 _Pediatrics, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA,_ 2 _Pediatric Anesthesia, Biomedical Ethics, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA,_ 3 _Bioethics and Humanities, Medicine, University of Washington Medical Center, Seattle, WA,_ 4 _Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA_

4:30 PM - 6:00 PM

## SYMPOSIUM 08: ECMO in Pre-Capillary PH: What is the Best Option for My Patient?

Location:

Grand Hall D

Target Audience:

PH, HF, LTX, PEDS, PH

**Chairs:**

Ellie Fadel, MD, and Corey E Ventetuolo, MD

**Session Summary:** ECMO options in patients with pre-capillary PH are multiple. They include peripheral VA ECMO through the lower or upper body, central ECMO, VV ECMO, or the new option of oxyRVAD. The indications depend on the patient conditions and underlying cause of PH. This symposium presents an overview of the different options and their application according to the sub-group of patients. There will be a focus on pediatric patients with PAH, adult patients with PAH, IPF-PH patients, and CTEPH patients. A panel discussion with all speakers will conclude this session.

4:30 PM

Peripheral vs. Central: ECMO in PAH Patients

Olaf Mercier, MD, PhD, Centre Chirurgical Marie Lannelongue, Fontenay aux roses, France

4:50 PM

OxyRVAD: Who is a Candidate?

Charles Hoopes, MD, University of Alabama, Birmingham, AL, USA

5:10 PM

ECMO in Pediatric Patients with PAH: What are the Particularities?

Pirooz Eghtesady, MD, St. Louis Children's Hospital, St Louis, MO, USA

5:30 PM

ECMO in Non-PAH Pulmonary Hypertension: Clots and Scars

Walter Klepetko, MD, Medical University of Vienna, Vienna, Austria

5:50 PM

Panel Discussion

4:30 PM - 6:00 PM

## **SYMPOSIUM 09: JHLT at ISHLT : The Year in a Capsule** ****

Location:

Coronado A-C

Target Audience:

ALL

**Chairs:**

Duane Davis, MD, MBA, and Martin Schweiger, MD, PhD

**Session Summary:** This session will highlight the most impactful publications in JHLT over the past year. Following the presentation of each publication by a member of the Junior Faculty and Trainee Council a senior editorial consultant of the JHLT will relate the presented articles to the greater body of published literature and discuss how they advance our understanding of the field.

4:30 PM

Introduction and Recognition of Top Papers of the Year

Patricia Uber, PharmD, Virginia Commonwealth University, Richmond, VA, USA

4:40 PM

Highlights of Heart Transplantation and Mechanical Circulatory Support

Agnieszka Ciarka, MD, Catholic University of Leuven, Leuven, Belgium

4:55 PM

Senior Editor Perspective: Heart Transplantation and Mechanical Circulatory Support

Hermann Reichenspurner, MD, PhD, University Heart Centre Hamburg, Hamburg, Germany

5:00 PM

Highlights of Lung Transplantation and Pulmonary Hypertension

Hrishikesh S Kulkarni, MD, Washington University School of Medicine, St. Louis, MO, USA

5:15 PM

Senior Editor Perspective: Lung Transplantation and Pulmonary Hypertension

Andrew J Fisher, FRCP, PhD, Freeman Hospital, Newcastle upon Tyne, United Kingdom

5:20 PM

Highlights of Pediatric Heart and Lung Transplantation

Erin Albers, MD, Seattle Children's Hospital, Seattle, WA, USA

5:35 PM

Senior Editor Perspective: Pediatric Heart and Lung Transplantation

Jennifer Conway, MD, Stollery Children's Hospital, Edmonton, AB, Canada

5:40 PM

Highlights of Infectious Diseases

Saima Aslam, MD, MS, UCSD Medical Center, San Diego, CA, USA

5:55 PM

Senior Editor Perspective: Infectious Diseases

Margaret Hannan, MD, Mater Misericordiae University Hospital, Dublin, Ireland

6:15 PM - 7:15 PM

## MINI ORAL SESSION 1: Complicating Factors in MCS

Location:

Grand Hall A

Target Audience:

MCS, HF, HTX, NHSAH, PHARM

**Chairs:**

Dipanjan Banerjee, MD, and Sung Ho Jung, MD

**6:15 PM** ( **75)** Preoperative Screening for Anti-Platelet Factor 4/Heparin Antibodies Does Not Accurately Predict Heparin-Induced Thrombocytopenia Post VAD; __ J. D. Plamenac1, J. Kumar1, G. Lee2, D. Yu3, Y. Toyoda4, R. Alvarez5, E. Hamad5. 1 _Internal Medicine, Temple University Hospital, Philadelphia, PA,_ 2 _Department of Internal Medicine, University of California, Irvine School of Medicine, Irvine, CA,_ 3 _Department of Clinical Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA,_ 4 _Cardiovascular Surgery, Temple University Hospital, Philadelphia, PA,_ 5 _Section of Cardiology, Temple University Hospital, Philadelphia, PA_

**6:20 PM** ( **76)** The Effect of Infections in VAD Recipients on Survival and Risk of Thromboembolism; __ S. B. Katugaha1, M. Gibreal2, A. C. Carter3, J. A. Cowger4, C. T. Salerno4, S. Maltais5, S. Dunlay6, T. F. Dardas7, K. D. Aaronson8, F. D. Pagani8, J. Stulak5, P. Shah9. 1 _Infectious Diseases, Inova Heart and Vascular Institute, Falls Church, VA,_ 2 _Infectious Diseases, George Washington Universtiy Hospital, Washington, DC,_ 3 _Infectious Diseases, INOVA Fairfax Hospital, Annandale, VA,_ 4 _St. Vincent Heart Center of Indiana, Indianapolis, IN,_ 5 _Mayo Clinic, Rochester, MN,_ 6 _Department of Cardiovas Med, Mayo, Rochester, MN,_ 7 _University of Washington, Seattle, WA,_ 8 _University of Michigan Health System, Ann Arbor, MI,_ 9 _Inova Heart and Vascular Institute, Falls Church, VA_

**6:25 PM** ( **77)** Driveline Site Is Not a Predictor of Infection Following Ventricular Assist Device Implantation; __ J. G. Luc1, B. Martin1, R. MacArthur1, A. R. Bates2, H. Buchholz1, D. H. Freed1, J. Conway3. 1 _Surgery, University of Alberta, Edmonton, AB, Canada,_ 2 _Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA,_ 3 _Pediatrics, University of Alberta, Edmonton, AB, Canada_

**6:30 PM** ( **78)** The Impact of LVAD Related Infections on Post Cardiac Transplant Outcomes: A Systematic Review; __ D. Chahal1, A. J. Wright2, M. Toma3. 1 _University of British Columbia, Vancouver, BC, Canada,_ 2 _Division of Infectious Diseases, University of British Columbia, Vancouver, BC, Canada,_ 3 _Division of Cardiology, University of British Columbia, Vancouver, BC, Canada_

**6:35 PM** ( **79)** Bloodstream Infection in Patients with LVAD and CIED; __ M. Gibreal1, S. Katugaha2, K. Abdullah3, J. Stulak4, J. A. Cowger5, C. Salerno5, S. Maltais6, S. M. Dunlay4, T. F. Dardas7, K. D. Aaronson8, F. D. Pagani8, P. Shah3. 1 _Cardiovascular Disease, George Washington University, Washington, DC,_ 2 _Infectious Diseases, Inova Heart and Vascular Institute, Falls Church, VA,_ 3 _Inova Heart and Vascular Institute, Falls Church, VA,_ 4 _Cardiovascular Disease, Mayo Clinic, Rochester, MN,_ 5 _St. Vincent Heart Center of Indiana, Indianapolis, IN,_ 6 _Mayo Clinic, Rochester, MN,_ 7 _Cardiovascular Disease, University of Washington, Seattle, WA,_ 8 _University of Michigan Health System, Ann Arbor, MI_

**6:40 PM** ( **80)** Antimicrobial Surgical Prophylaxis in MCS Implant Surgery and Surgical Site Infection, IMACS January 2013 to December 2015; __ M. M. Hannan1, R. Xie2, S. Kusne3, C. Merry4, P. Grossi5, V. Stosor6, C. Sivathasan7, M. Mehra8, U. Jorde9, I. Netuka10, S. Huprikar11, J. K. Kirklin2. 1 _Mater Misericordiae University Hospital, Dublin, Ireland,_ 2 _The James and John Kirklin Institute for Research in Surgical Outcomes (KIRSO) UAB, Birmingham, AL,_ 3 _Mayo Clinic, Scottsdale, AZ,_ 4 _Fiona Stanley Hospital, Perth, Australia,_ 5 _University of Insubria, Varese, Italy,_ 6 _Northwest Univercity, Chicago, IL,_ 7 _National Heart Centre, Singapore, Singapore,_ 8 _Brigham and Womens Hospital, Boston, MA,_ 9 _Albert Einstein College of Medicine, NewYork, NY,_ 10 _Cardiothoracic Surgery, Prague, Czech Republic,_ 11 _The Mount Sinai Hospital, New York, NY_

**6:45 PM** ( **81)** Frequency and Risk Factors for Acquired Infections During ECMO; __ N. Selcuk, M. Sargin, M. E. Mete, S. B. Erdogan, M. Bastopçu, S. Ocalmaz, G. Orhan, S. A. Aka. _Cardiovascular Surgery, Siyami Ersek Hospital, Istanbul, Turkey_

**6:50 PM** ( **82)** Increased Rate of Pump Thrombosis and Cardioembolic Events Following Ventricular Tachycardia Ablation in Patients Supported with Left Ventricular Assist Devices; __ J. Grinstein1, A. R. Garan2, E. Flatley1, G. H. Kim1, X. Mai2, N. Sarswat1, S. Kalantari1, S. Adatya1, J. Raikhelkar1, G. Sayer1, A. Oesterle1, V. Jeevanandam1, J. Moss3, N. Uriel1. 1 _University of Chicago, Chicago, IL,_ 2 _Columbia University, New York, NY,_ 3 _University of California San Francisco, San Francisco, CA_

**6:55 PM** ( **83)** Neurological Complications in Patients Supported with Continuous Flow Left Ventricular Assist Devices - Comparative Analysis of HeartMate II and HeartWare Devices; __ M. Kawabori, C. Kurihara, T. Sugiura, L. Cunningham, A. Civitello, W. E. Cohn, O. H. Frazier, J. Morgan. _Texas Heart Institute, Baylor College of Medicine, Houston, TX_

**7:00 PM** ( **84)** Impact of Body Mass Index on Outcomes After Left Ventricular Assist Device Placement: Evidence from a Meta-Analysis; __ A. Vallakati, S. Emani, W. T. Abraham. _Cardiovascular Diseases, The Ohio State University, Columbus, OH_

**7:05 PM** ( **85)** Effect of Preoperative Atrial Fibrillation on Patients with Undergoing Implantation of Long-Term Continuous Flow Ventricular Assist Devices; __ C. Kurihara, M. Kawabori, T. Sugiura, W. E. Cohn, A. B. Civitello, O. Frazier, J. A. Morgan. _Baylor College of Medicine, Houston, TX_

**7:10 PM** ( **86)** Effects of Diabetes Mellitus on Clinical Outcomes After Left Ventricular Assist Device Implantation: A Single Institutional 9-Year Experience; __ R. Asleh, S. D. Schettle, A. Briasoulis, V. Tchantchaleishvili, N. Pereira, B. Edwards, A. L. Clavell, S. Maltais, D. L. Joyce, S. J. Park, L. D. Joyce, R. Daly, S. Kushwaha, J. M. Stulak. _Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN_

6:15 PM - 7:15 PM

## MINI ORAL SESSION 2: Donor Evaluation and Management: DBD and DCD

Location:

Grand Hall B

Target Audience:

HTX, EEP, MCS

**Chairs:**

Hannah Copeland, MD, and Alexander M Bernhardt, MD

**6:15 PM** ( **87)** Utilizing Expanded Donor Selection Criteria for Heart Transplantation: A Single Center Experience; __ N. Rajagopalan, D. R. Dennis, H. L. Ross, P. Tessmann, A. Shafii, M. E. Sekela. _University of Kentucky, Lexington, KY_

**6:20 PM** ( **88)** Performing Coronary Angiography in High Risk Cardiac Donors Does Not Affect Renal Function in Kidney Recipients; __ M. Lesouhaitier1, C. Legeai2, E. Savoye2, C. Cantrelle2, I. Pipien2, M. Macher2, C. Vigneau1, R. Dorent2. 1 _CHU Rennes, Rennes, France,_ 2 _Agence de la Biomédecine, Saint-Denis, France_

**6:25 PM** ( **89)** Donor Heart Diastolic Dysfunction: Do You Take This Heart for Transplantation?; __ F. Liou, M. Kittleson, J. Patel, T. Aintablian, T. Kao, E. Kransdorf, D. Geft, D. H. Chang, L. Czer, D. Ramzy, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**6:30 PM** ( **90)** Does Distance from Donor Hospital Impact Survival in Heart Transplant Recipients?; __ Y. Ravi1, E. M. Stock2, S. K. Lella3, J. V. Balasubramaniyan4, S. Emani5, C. B. Sai-Sudhakar1. 1 _Cardiac Surgery, Scott & White, Texas A&M, Temple, TX, _2 _Center for Applied Health Research, US Department of Veteran Affairs, Perry Point, MD,_ 3 _Texas A &M Health Science Centre College of Medicine, Temple, TX, _4 _Cardiology, Sri Ramachandra University, Chennai, India,_ 5 _Internal Medicine, The Ohio State University, Columbus, OH_

**6:35 PM** ( **91)** Donor Heart Turn Down in the Field: What's Going On?; __ J. Patel, M. Kittleson, T. Aintablian, J. Kwan, N. Musto, B. Kearney, D. Geft, D. H. Chang, L. Czer, F. Esmailian, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**6:40 PM** ( **92)** Ischemia Time and the Eurotransplant Heart Donor Score as Predictors for Primary Graft Dysfunction; __ T. Haberl1, J. Riebandt1, A. Z. Aliabadi-Zuckermann1, D. Wiedemann1, R. Moayedifar1, E. Osorio1, D. Hutschala2, G. Laufer1, A. Zuckermann1. 1 _Division of Cardiac Surgery, Medical University of Vienna, Vienna, Austria,_ 2 _Department of Anesthesiology and Pain Care, Medical University of Vienna, Vienna, Austria_

**6:45 PM** ( **93)** Comparison of Functional and Metabolic Assessment of Integrity of Human Donor Hearts: Possible Application for Donation After Circulatory Death; __ P. Bhaskaran1, R. Ou1, S. Perera2, F. L. Rosenfeldt1. 1 _Department of Surgery, Monash University, Melbourne, Australia,_ 2 _Cardiothoracic Surgery, Alfred Hospital, Melbourne, Australia_

**6:50 PM** ( **94)** Predicting Progression to Cessation of Circulation in the Pathway of Organ Donation After Circulatory Death; __ M. S. Fulton1, M. Connellan2, M. Harkess2, K. Dhital2. 1 _Faculty of Medicine, University of New South Wales, Sydney, Australia,_ 2 _Heart and Lung Transplant Unit, St Vincent's Hospital, Sydney, Australia_

**6:55 PM** ( **95)** Ex-Vivo Perfusion of a Human Heart Recovered from a DCD Donor for 13 Hours on Organ Care System Platform; __ J. W. Smith1, R. J. Madathil1, J. D. Pal1, J. Hermsen1, C. Mahr2, R. L. Romig1, T. M. Arneberg3, N. A. Mokadam1. 1 _Cardiothoracic Surgery, University of Washington, Seattle, WA,_ 2 _Cardiology, University of Washington, Seattle, WA,_ 3 _Clinical Engineering, Transmedics, Inc., Andover, MA_

**7:00 PM** ( **96)** Outcome After Warm Machine Perfusion (WMP) Recovery of Marginal Brain Dead (MBD) and Donation After Circulatory Death (DCD) Heart Transplantation; __ H. Chew1, C. Cheong2, M. Fulton2, M. Shah1, A. Doyle3, L. Gao3, J. Villanueva3, C. Soto4, M. Hicks5, M. Connellan1, E. Granger1, P. Jansz1, P. Spratt1, C. Hayward6, A. Keogh6, E. Kotlyar6, A. Jabbour6, K. Dhital1, P. Macdonald6. 1 _Cardiothoracic Surgery, St Vincent's Hospital, Darlinghurst, Australia,_ 2 _Clinical School, St Vincent's Hospital, Darlinghurst, Australia,_ 3 _Cardiac Transplantation Laboratory, Victor Chang Cardiac Research Insitute, Darlinghurst, Australia,_ 4 _Cardiac Perfusion, St Vincent's Hospital, Darlinghurst, Australia,_ 5 _Clinical Pharmacology and Toxicology, St Vincent's Hospital, Darlinghurst, Australia,_ 6 _Heart Lung Clinic, St Vincent's Hospital, Darlinghurst, Australia_

**7:05 PM** ( **97)** Transition of DCD Heart Transplantation from Research to a Clinical Programme - Challenges and Lessons Learned; __ M. Berman, E. Pavlushkov, H. Doshi, S. Balasubramanian, D. White, S. Claydon, H. Ballantyne, C. Ellis, S. Tsui. _Papworth Hospital NHS Foundation Trust, Cambridge, United Kingdom_

**7:10 PM** ( **98)** Post-Transplant Assessment of DCD Cardiac Allografts with MRI; __ E. Pavlushkov1, A. Page1, S. Messer1, A. Kydd1, K. Tweed2, Y. Abu-Omar1, A. Ali1, M. Berman1, P. Catarino1, J. Dunning1, D. Jenkins1, C. Lewis3, J. Parameshwar3, S. Pettit3, C. Sudarshan1, S. Tsui1, S. Large1. 1 _Cardiothoracic Transplantation, Papworth Hospital, Cambridge, United Kingdom,_ 2 _Radiology, Papworth Hospital, Cambridge, United Kingdom,_ 3 _Transplant Cardiology, Papworth Hospital, Cambridge, United Kingdom_

6:15 PM - 7:15 PM

## MINI ORAL SESSION 3: Wretched Strangers: Mechanisms of Thoracic Organ Infection, Rejection and Tolerance

Location:

Grand Hall C

Target Audience:

BSTR, EEP, HF, HTX, ID, LTX, PATH, PEDS, PHARM, PH

**Chairs:**

Stephen C Juvet, MD, PhD, FRCPC, and Michael G Ison, MD MS

**6:15 PM** ( **99)** Circulating Xenograft-Derived Cell-Free DNA as a Reliable Marker for Injury After Xenotransplantation; __ S. Agbor-Enoh1, J. L. Chan2, I. Tunc3, A. Singh2, S. Gorham1, J. Zhu4, M. Pirooznia4, P. Corcoran2, M. L. Thomas III2, B. Lewis5, M. Jang1, D. L. Ayares6, K. Horvath2, H. A. Valantine1, M. M. Mohiuddin2. 1 _Laboratory of Transplant Genomics, Nat'l Inst. of Health, Bethesda, MD,_ 2 _Cardiothoracic Surgery Research Program, National Heart, Lung, and Blood Institute, Nat'l Inst. of Health, Bethesda, MD,_ 3 _Bioinformatics and Computation Core, National Heart, Lung, and Blood Institute, Nat'l Inst. of Health, Bethesda, MD,_ 4 _Genomic and Computation Core, National Heart, Lung and Blood Institute, Nat'l Inst. of Health, Bethesda, MD,_ 5 _Division of Veterinary Resources, Nat'l Inst. of Health, Bethesda, MD,_ 6 _Revivicor, Inc, Blacksburg, VA_

**6:20 PM** ( **100)** Cis-Binding of the Inhibitory Molecule CD22 to CD22 Ligand (CD22L) Controls Activation of Human CD27+IgM+ B Cells; __ E. Dijke, K. Derkatz, J. Pearcey, F. Wong, B. Motyka, L. West. _Pediatrics/Alberta Transplant Institute, University of Alberta, Edmonton, AB, Canada_

**6:25 PM** ( **101)** The Degree of CMV-Specific T Cell Response Is Related with Infection Complications in Heart Transplant Recipients; __ J. Youn1, J. Lee2, S. Han1, S. Kang3, E. Shin2. 1 _Hallym University, Gyeonggido, Korea, Republic of,_ 2 _KAIST, Daejeon, Korea, Republic of,_ 3 _Yonsei University, Seoul, Korea, Republic of_

**6:30 PM** ( **102)** Influence of Donor Cytomegalovirus (CMV) Immunoglobulin G (IgG) Optical Density on CMV Transmission to CMV Naïve Lung Transplant Recipients; __ C. Hernandez, A. Hirji, D. Kabbani, S. Fuentes, H. Mahli, S. Chandrarathne, K. Halloran, J. Weinkauf, A. Kapasi, D. Lien, J. Preiksaitis, C. Cervera. _Medicine, University of Alberta, Edmonton, AB, Canada_

**6:35 PM** ( **103)** Airway-Centered Inflammation Induced by Lipopolysaccharide (LPS) Leads to BOS-Like Phenotype of CLAD in Rat Lung Transplantation; __ A. Takahagi1, M. Sato2, T. Chen-Yoshikawa1, A. Yoshizawa3, K. Ohata1, M. Saito1, R. Okabe1, F. Gochi1, H. Yamagishi1, M. Hamaji1, H. Motoyama1, K. Hijiya1, A. Aoyama1, H. Date1. 1 _Thoracic Surgery, Kyoto University Gradual School, Kyoto, Japan,_ 2 _Thoracic Surgery, the University of Tokyo, Tokyo, Japan,_ 3 _Diagnostic Pathology, Kyoto University Hospital, Kyoto, Japan_

**6:40 PM** ( **104)** Alternatively Activated Naive Human T Cells Exhibit Strong Suppressive Capacity in a Humanized Transplant Arteriosclerosis Model; __ L. Pauksch, W. Sommer, K. Jansson, A. Knoefel, T. Nakagiri, A. Haverich, G. Warnecke. _Department of Cardiac, Thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany_

**6:45 PM** ( **105)** Nitric Oxide Producing Eosinophils Play a Critical Role in Lung Allograft Acceptance; __ O. O. Onyema1, Y. Guo1, A. E. Gelman2, D. Kreisel2, J. J. Lee3, A. S. Krupnick1. 1 _Department of Surgery, University of Virginia, Charlottesville, VA,_ 2 _Department of Surgery, Washington University, St Louis, MO,_ 3 _Department of Biochemistry and Molecular Biology, Mayo Clinic, Scottsdale, AZ_

**6:50 PM** ( **106)** Tolerance Induction by Myeloid Progenitor Cells: Matching Requirements and Expanded Model; __ Y. Li1, A. Sedello2, T. Fong2, J. Domen1. 1 _Cardiac Surgery, Children's Mercy Hospital and Clinics, Kansas City, MO,_ 2 _Cellerant Therapeutics, San Carlos, CA_

**6:55 PM** ( **107)** Blood Group A-Antigen Specific Tolerance Following Exposure to A-Antigen in Infant Mice; __ B. Motyka1, Y. Wang2, B. Lamarche2, I. Adam1, J. Pearcey3, K. Tao3, C. W. Cairo4, P. J. Cowan5, L. J. West1. 1 _Dept Pediatrics, Alberta Transplant Institute, Canadian National Transplant Research Program, University of Alberta, Edmonton, AB, Canada,_ 2 _Dept Pediatrics, University of Alberta, Edmonton, AB, Canada,_ 3 _Dept Pediatrics, Alberta Transplant Institute, University of Alberta, Edmonton, AB, Canada,_ 4 _Dept Chemistry, Alberta Glycomics Centre, University of Alberta, Edmonton, AB, Canada,_ 5 _Immunology Research Centre, St Vincent's Hospital, Melbourne, Australia_

**7:00 PM** ( **108)** Effect of Perioperative Treatment with Adenosine A2A Receptor Agonist on Pulmonary Allograft Survival in MHC-Inbred CLAWN Miniature Swine; __ H. Sahara, M. Sekijima, T. Murokawa, Y. Ariyoshi, T. Iwanaga, Y. Ichinari, A. Shimizu, K. Yamada. _Division of Organ Replacement of Xenotransplantation Surgery, Center for Advanced Biomedical Science and Swine Research, Kagoshima University, Kagoshima, Japan_

**7:05 PM** ( **109)** The Microbiome of the Respiratory Tract After Heart Transplantation; __ H. Joyce1, M. Hong1, M. Workentine1, A. Pinto1, S. Hirota1, M. Surette2, S. C. Greenway1. 1 _University of Calgary, Calgary, AB, Canada,_ 2 _McMaster University, Hamilton, ON, Canada_

**7:10 PM** ( **110)** Lower Pre-Transplant Memory Class-Switched B Cell Levels Are Associated with a High Risk of Severe Infection After Heart Transplantation; __ L. Calahorra1, E. Sarmiento1, A. Gallego1, S. Garcia1, E. Zatarain2, I. Sousa2, M. Valerio3, R. Lerma1, J. Navarro1, N. Lanio1, J. Carbone1. 1 _Clinical Immunology, Hospital General Universitario Gregorio Marañon, Madrid, Spain,_ 2 _Cardiology, Hospital General Universitario Gregorio Marañon, Madrid, Spain,_ 3 _Microbiology, Hospital General Universitario Gregorio Marañon, Madrid, Spain_

6:15 PM - 7:15 PM

## MINI ORAL SESSION 4: Allocation, Bridging and Lung Allograft Assessment Strategies

Location:

Grand Hall D

Target Audience:

LTX, BSTR, EEP, ID, MCS, NHSAH, PATH, PHARM

**Chairs:**

Hiroshi Date, MD, and Clemens Aigner, MD

**6:15 PM** ( **111)** Lung Allocation Score Is Not Created Equal: For a Given LAS, Waitlist Survival Varies by Diagnosis Among Lung Transplant Registrants; __ H. Maredia1, M. Bowring1, A. Massie1, S. Oyetunji1, C. Merlo2, R. Higgins1, D. Segev1, E. Bush1. 1 _Department of Surgery, Johns Hopkins University, Baltimore, MD,_ 2 _Department of Medicine, Johns Hopkins University, Baltimore, MD_

**6:20 PM** ( **112)** Lung Allocation Score Does Not Accurately Predict Post-Transplant Survival Among Cystic Fibrosis Lung Transplant Recipients; __ H. Maredia1, M. Bowring1, A. Massie1, S. Oyetunji1, C. Merlo2, R. Higgins1, D. Segev1, E. Bush1. 1 _Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD,_ 2 _Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD_

**6:25 PM** ( **113)** Lung Allocation Score Does Not Predict Survival Among Idiopathic Pulmonary Fibrosis Lung Transplant Recipients; __ H. Maredia1, M. Bowring1, A. Massie1, S. Oyetunji1, C. Merlo2, R. Higgins1, D. Segev1, E. Bush1. 1 _Department of Surgery, Johns Hopkins University, Baltimore, MD,_ 2 _Department of Medicine, Johns Hopkins University, Baltimore, MD_

**6:30 PM** ( **114)** Lung Transplant Experience with Public Health Services Increased Risk Donors: Recipient Outcomes and Incidence of Transmission and Conversion; __ C. A. Bermudez1, M. R. Molina1, A. M. Thomasson2, E. Blumberg3, J. Lee4, L. Gardo5, V. Ahya4, N. Blumenthal6, E. Cantu1, J. D. Christie4, A. Courtwright4, J. Diamond4, J. Golato6, D. Hadjiliadis4, E. J. Hobson6, N. Patel4, M. Porteous4, M. Crespo4. 1 _Cardiovascular Surgery, Hospital of the University of Pennsylvannia, Philadelphia, PA,_ 2 _Penn Transplant Statistician, Hospital of the University of Pennsylvannia, Philadelphia, PA,_ 3 _Infectious Disease Transplantation/Medicine, Hospital of the University of Pennsylvannia, Philadelphia, PA,_ 4 _Department of Pulmonary, Allergy & Critical Care Division, Hospital of the University of Pennsylvannia, Philadelphia, PA, _5 _Penn Performance Improvement Outcomes Specialist, Hospital of the University of Pennsylvannia, Philadelphia, PA,_ 6 _Penn Transplant Center Lung Program, Hospital of the University of Pennsylvannia, Philadelphia, PA_

**6:35 PM** ( **115)** Contemporary Outcomes of ECMO Used as Bridge to Lung Transplantation; __ A. H. Hakim1, U. Ahmad1, K. McCurry1, D. R. Johnston1, G. Pettersson1, M. Budev2, S. Murthy1, E. H. Blackstone1, M. Z. Tong1. 1 _Cardio-Thoracic Surgery, Cleveland Clinic Foundation, Cleveland, OH,_ 2 _Pulmonary Medicine, Cleveland Clinic Foundation, Cleveland, OH_

**6:40 PM** ( **116)** Mechanical Ventilation and Extracorporeal Membrane Oxygenation (ECMO) as a Combined Bridging Strategy to Lung Transplantation: Significant Gains in Survival; __ A. L. Du1, J. Hayanga2, J. D'Cunha2, M. Tuft3, M. Morrell4, N. Shigemura2. 1 _University of Pittsburgh School of Medicine, Pittsburgh, PA,_ 2 _Division of Cardiothoracic Transplantation, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA,_ 3 _Department of Biostatistics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA,_ 4 _Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA_

**6:45 PM** ( **117)** Risk Factors for Intraoperative Extracorporeal Circulatory Support in Patients Undergoing Lung Transplantation for Pulmonary Fibrosis; __ F. Ius1, J. Salman1, W. Sommer1, C. Kühn1, M. Avsar1, T. Siemeni1, D. Böthig1, M. Greer2, N. Schwerk3, J. Gottlieb2, T. Welte2, A. Haverich1, G. Warnecke1, I. Tudorache1. 1 _Department of Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany,_ 2 _Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany,_ 3 _Department of Paediatrics, Hannover Medical School, Hannover, Germany_

**6:50 PM** ( **118)** The Effect of Left-To-Right Shunt Using Veno-Arterial-Veno Extracorporeal Membrane Oxygenation (ECMO) on Oxygenation of Proximal Ascending Aorta in Lung Transplantation Patients; __ N. Kim1, J. G. Lee2, S. Lee2, J. W. Shu2, K. S. Nam2, Y. C. Yoo1, H. C. Paik2. 1 _Anesthesiology, Yonsei University, Seoul, Korea, Republic of,_ 2 _Thoracic and Cardiovascular Surgery, Yonsei University, Seoul, Korea, Republic of_

**6:55 PM** ( **119)** Development of a Donor Lung Discard Score to Prompt Assessment for Ex-Vivo Lung Perfusion Reconditioning; __ C. Legeai1, C. Picard2, C. Pison3, E. Sage2, O. Mercier4, O. Huot1, R. Dorent1. 1 _Agence de la Biomédecine, Saint-Denis, France,_ 2 _Hôpital Foch, Suresnes, France,_ 3 _CHU de Grenoble, Grenoble, France,_ 4 _Hôpital Marie-Lannelongue, Le Plessis Robinson, France_

**7:00 PM** ( **120)** Important Implication in Evaluation of Donor Lungs in Single Lung Ex Vivo Lung Perfusion; __ H. Niikawa1, T. Okamoto2, K. Ayyat1, Y. Itoda1, K. R. McCurry2. 1 _Pathobiology, Cleveland Clinic, Cleveland, OH,_ 2 _Thoracic & Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH_

**7:05 PM** ( **121)** Comparison of Two Strategies for Experimental Ex-Vivo Lung Perfusion - Cellular Solution and Open Atrium versus Acellular Solution and Closed Atrium; __ T. Nilsson1, J. Gielis2, C. Hansson3, A. Wallinder3, A. Laffin3, S. Ricksten,1, G. Dellgren3. 1 _Dept of Anesthesiology and Intensive Care Medicine, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden,_ 2 _Department of Thoracic Surgery, Antwerp Surgical Training and Anatomy Research Centre, Antwerp University, Antwerp, Belgium,_ 3 _Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden_

**7:10 PM** ( **122)** Carbon Monoxide Can Rescue Lungs from Controlled Donors After Cardiac Death and Prolonged Warm Ischemia; __ Y. Watanabe, D. Nakajima, Y. Taniguchi, M. Pipkin, M. Chen, R. Qaqish, L. Caldarone, T. Watanabe, A. Ohsumi, T. Kanou, M. Takahashi, A. Gazzalle, M. Galasso, A. Ali, C. Summers, T. K. Waddell, M. Liu, S. Keshavjee, M. Cypel. _Latner Thoracic Surgery Research Laboratories, Toronto General Research Institute, University Health Network, University of Toronto, Toronto, ON, Canada_

6:15 PM - 7:15 PM

## MINI ORAL SESSION 5: The Hardware of MCS

Location:

Seaport F-H

Target Audience:

MCS, HF, NHSAH

**Chairs:**

David A Baran, MD, and Melana Yuzefpolskaya, MD

**6:15 PM** ( **123)** Evaluation of a Virtual Implant Technique to Optimise Implantation of a Bioprosthetic Total Artificial Heart; __ C. Latrémouille1, J. C. Roussel2, M. Kindo3, P. Leprince4, D. Duveau5, B. Tchakgarian6, J. C. Perlès6, P. Jansen6, A. Carpentier1. 1 _Cardiovascular Surgery, Hôpital Européen Georges Pompidou, APHP, Université Paris Descartes-Sorbonne Paris Cité, Paris, France,_ 2 _Cardiovascular Surgery, Hôpital Guillaume et René Laënnec, Université de Nantes, Saint-Herblain, France,_ 3 _Cardiovascular Surgery, Nouvel Hôpital Civil, Université de Strasbourg, Strasbourg, France,_ 4 _Cardiovascular Surgery, Groupe Hospitalier Pitié-Salpétrière, APHP, Université Pierre et Marie Curie, Paris, France,_ 5 _Cardiovascular Surgery, Faculté de Médecine, Université de Nantes, Nantes, France,_ 6 _Carmat SA, Vélizy-Villacoublay, France_

**6:20 PM** ( **124)** Performance of a Novel Shuttling Total Artificial Heart on a on a Mock Circulatory Loop; __ R. Wampler1, J. Glynn2, S. Withers2, B. Hull2, M. Slaughter3, A. Starr1, H. K. Song1. 1 _Cardiothoracic Surgery, Oregon Health & Science University, Portland, OR, _2 _Oregon Heart, Inc, Portland, OR,_ 3 _Cardiothoracic Surgery, University of Louisville, Louisville, KY_

**6:25 PM** ( **125)** Increased Right Ventricular Afterload Is Associated with Poor Survival Among Patients Receiving Biventricular Impella (BiPella) Support for Cardiogenic Shock; __ M. Esposito1, S. Kuchibhotla1, B. Catalina1, O. Ryan1, R. Pedicini1, M. Andrew1, S. Annamalai1, G. Mark2, M. Kiernan1, D. T. Pham3, M. Anderson4, D. Morris5, G. Batsides6, R. Danny7, N. K. Kapur1. 1 _Cardiology, Tufts Medical Center, Boston, MA,_ 2 _Cardiology, Sacred Heart Medical Group, Pensacola, FL,_ 3 _Cardiology, Northwestern Memorial Hospital, Chicago, IL,_ 4 _Cardiothoracic Surgery, Einstein Medical Center, Philadelphia, PA,_ 5 _Cardiology, Einstein Medical Center, Philadelphia, PA,_ 6 _Cardiothoracic Surgery, Robert Wood Johnson University Hospital, New Brunswick, NJ,_ 7 _Cardiothoracic Surgery, Cedars Sinai Medical Center, Los Angeles, CA_

**6:30 PM** ( **126)** Successful Use of Temporary Percutaneous Right Ventricular Assist Devices in Acute Right Ventricular Failure After Acute Myocardial Infarction or LVAD Implantation; __ E. Coromilas, K. Takeda, A. Kirtane, V. K. Topkara, H. Takayama, M. Yuzefpolskaya, D. Karmpaliotis, Y. Naka, P. C. Colombo, A. R. Garan. _Columbia University, New York, NY_

**6:35 PM** ( **127)** Advantage of Bridge to Transplantation with Subclavian Intra-Aortic Balloon Pump Compared to Left Ventricular Assist Device Support; __ H. Kitahara, C. Juricek, D. Onsager, J. Reikhelkar, G. Kim, N. Sarswat, S. Adatya, G. Sayer, N. Uriel, T. Song, V. Jeevanandam, T. Ota. _Cardiac Surgery, The University of Chicago, Chicago, IL_

**6:40 PM** ( **128)** Device Exchange Is Superior to Medical Therapy for Treating Continuous-Flow Left Ventricular Assist Device Thrombosis; __ H. Kitahara, C. Juricek, D. Onsager, J. Reikhelkar, G. Kim, N. Sarswat, S. Adatya, G. Sayer, N. Uriel, T. Song, V. Jeevanandam, T. Ota. _Cardiac Surgery, The University of Chicago, Chicago, IL_

**6:45 PM** ( **129)** Mechanical Circulatory Support for Patients in Cardiogenic Shock After Right Ventricular Infarction: A Single-Center Experience; __ K. Patel, K. Takeda, L. Truby, C. Eckhardt, K. Ross, D. Karmpaliotis, Y. Naka, V. K. Topkara, M. Yuzefpolskaya, P. C. Colombo, A. Kirtane, H. Takayama, A. R. Garan. _Columbia University, New York, NY_

**6:50 PM** ( **130)** Durable LeftVentricular Assist Device Therapy to Reduce Transpulmonary Gradient in Adult Congenital Heart Disease to Facilitate Heart Transplant; __ A. Woods, G. MacGowan, N. Robinson-Smith, L. Kenny, A. Hasan, S. Schueler. _Cardiothoracic, Newcastle upon Tyne NHS Foundations Trust, Newcastle upon Tyne, United Kingdom_

**6:55 PM** ( **131)** Association Between the Use of Invasive Hemodynamic Monitoring and Outcomes with Percutaneous Left Ventricular Support: A Call for Standardization?; __ J. J. Teuteberg1, W. O'Neill2. 1 _University of Pittsburgh, Pittsburgh, PA,_ 2 _Henry Ford, Detroit, MI_

**7:00 PM** ( **132)** Analysis of Right Ventricular (RV) Regional and Global Systolic Function by Gated Blood Pool SPECT (GBPS) in Patients Undergoing Left Ventricular Assist Device (LVAD) Implantation; __ C. B. Link, A. Nayak, P. Soman, M. A. Simon, J. J. Teuteberg, L. Lagazzi, A. Althouse, R. Kormos. _HVI, UPMC, Pittsburgh, PA_

**7:05 PM** ( **133)** Emerging Science of Hemocompatibility as Applied to VAD Design and Pre-Clinical Evaluation; __ J. W. Long1, T. Snyder2, J. R. Stanfield3. 1 _Integris Health, Oklahoma City, OK,_ 2 _VADovations, Oklahoma City, OK,_ 3 _University of Utah, Oklahoma City, OK_

**7:10 PM** ( **134)** Minimally Invasive versus Sternotomy Approach for Centrimag Biventricular Support in Refractory Cardiogenic Shock; __ K. Takeda, A. R. Garan, V. K. Topkara, J. Han, P. Kurlansky, M. Yuzefpolskaya, M. A. Farr, P. C. Colombo, Y. Naka, H. Takayama. _Columbia University, NY, NY_

6:15 PM - 7:15 PM

## MINI ORAL SESSION 6: Therapeutics in Advanced Heart and Lung Disease

Location:

Coronado A-C

Target Audience:

PHARM, HTX, ID, LTX, MCS, NHSAH

**Chairs:**

Douglas L. Jennings, PharmD, and Amanda Ingemi, PharmD

**6:15 PM** ( **135)** Combination Abbreviated Inhaled Ribavirin and Oral Ribavirin Therapy for Respiratory RNA Viruses in Lung Transplant; __ A. T. Logan1, S. Kapadia2, E. Schwaiger2, T. Haddad3, K. Patel2. 1 _Department of Pharmacy, Tampa General Hospital, Tampa, FL,_ 2 _Department of Pulmonary Critical Care, University of South Florida, Tampa, FL,_ 3 _Department of Pulmonary Critical Care, Tampa General Hospital, Tampa, FL_

**6:20 PM** ( **136)** Single-Center Experience with Epstein-Barr Virus Screening in Lung Transplant Recipients to Identify Patients with Post-Transplant Lymphoproliferative Disorder; __ D. Owen1, K. Dawson1, B. Pierce1, A. Goodarzi2, N. Sinha2, J. Youssef2, T. Kaleekal2. 1 _Department of Pharmacy, Houston Methodist Hospital, Houston, TX,_ 2 _J.C. Walter Jr. Transplant Center, Houston Methodist Hospital, Houston, TX_

**6:25 PM** ( **137)** Infectious Complications Following Rituximab in Lung Transplantation: A Propensity-Matched Cohort; __ J. Rago1, K. B. Bain2, K. A. Fester2, T. A. Horwedel2, J. I. Melaragno3, C. A. Witt4, R. R. Hachem4. 1 _Pharmacy, Methodist Dallas Medical Center, Dallas, TX,_ 2 _Pharmacy, Barnes Jewish Hospital, St. Louis, MO,_ 3 _Pharmacy, University of Rochester Medical Center, Rochester, NY,_ 4 _Pulmonary and Critical Care Medicine, Washington University, St. Louis, MO_

**6:30 PM** ( **138)** Comparative Efficacy of Azathioprine versus Mycophenolate in Lung Transplant Recipients; __ M. A. Olson1, K. B. Bain1, K. A. Fester1, C. Chen2, R. R. Hachem3. 1 _Pharmacy, Barnes Jewish Hospital, St. Louis, MO,_ 2 _Internal Medicine, UT Southwestern, Dallas, TX,_ 3 _Pulmonary and Critical Care Medicine, Washington University, St. Louis, MO_

**6:35 PM** ( **139)** Characterization of Unfractionated Heparin Dosing Requirements in Cystic Fibrosis; __ K. B. Bain1, B. R. Tellor1, K. A. Fester1, R. D. Yusen2. 1 _Pharmacy, Barnes Jewish Hospital, St. Louis, MO,_ 2 _Pulmonary and Critical Care Medicine, General Medical Science, Washington University School of Medicine, St. Louis, MO_

**6:40 PM** ( **140)** Four Factor Prothrombin Complex Concentrate and the Risk of Thrombosis in Continuous Flow LVAD; __ J. Rimsans1, A. Levesque1, R. Nashett1, H. Badreldin1, E. Lyons2, K. Sylvester1, G. C. Stewart2, J. M. Connors3. 1 _Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA,_ 2 _Cardiovascular Division, Brigham and Women's Hospital, Boston, MA,_ 3 _Division of Hematology, Brigham and Women's Hospital, Boston, MA_

**6:45 PM** ( **141)** Four-Factor Prothrombin Complex Concentrate for Bleeding in Patients with LVADs; __ B. Tellor1, J. Shuster1, T. Human1, S. LaRue2, J. Vader2, K. Balsara3. 1 _Pharmacy, Barnes-Jewish Hospital, St. Louis, MO,_ 2 _Int Med - Cardiovascular Division, Washington University School of Medicine, St. Louis, MO,_ 3 _Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, MO_

**6:50 PM** ( **142)** A Genotype Guided Warfarin Protocol Improves Anticoagulation Quality Early After LVAD Implantation; __ D. L. Jennings, M. Yuzefpolskaya, A. R. Garan, A. Eisenberger, K. Takeda, H. Takayama, Y. Naka, P. Colombo, V. Topkara. _Columbia University Irving Medical Center, New York, NY_

**6:55 PM** ( **143)** PDE5i Initiation in Patients with Right Ventricular Dysfunction Post-LVAD Does Not Improve Right Ventricular Function; __ J. E. Shuster1, K. Roberts1, S. LaRue2, B. Tellor1. 1 _Barnes-Jewish Hospital, Saint Louis, MO,_ 2 _Washington University in Saint Louis, Saint Louis, MO_

**7:00 PM** ( **144)** Effect of ABCB1 Haplotypes on Tacrolimus Disposition in Heart Transplant Recipients; __ K. Oreschak1, K. M. Deininger1, A. V. Ambardekar1, R. L. Page II1, J. Lindenfeld2, C. L. Aquilante1. 1 _University of Colorado, Aurora, CO,_ 2 _Vanderbilt University, Nashville, TN_

**7:05 PM** ( **145)** Early CNI-Free Immunosuppression Post Heart Transplantation to Recover Renal Function - A Single Centre Experience; __ A. Hartley, H. Lyster, D. Dhar, M. P. Lythgoe, P. Kourkoveli, F. De Robertis, A. R. Simon, N. Banner, O. Dar. _Royal Brompton & Harefield NHS Trust, London, United Kingdom_

**7:10 PM** ( **146)** The Risks and Rewards of Desensitization Therapies for Heart Transplant Candidates; __ C. Carson, C. T. Doligalski. _Tampa General Hospital, Lutz, FL_

# Thursday, April 06, 2017

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 01: Walk With Me: Exercise Physiology in the LVAD Patient

Location:

Grand Hall A

Target Audience:

MCS, ALL

**Chairs:**

Christopher S Hayward, MD, and Jorge Silva Enciso, MD

**Session Summary:** Ventricular assist devices improve functional class and quality of life due to its impact on exercise capacity. Long-term LVAD support is associated with improved central hemodynamics and exercise performance. Although, the maximal effects on functional performance continue to be marginal, pump flow changes and cardiac output augmentation does occur during exercise. Understanding the basis of exercise physiology in LVAD patients may allow for future interventions to enhance exercise performance.

7:00 AM

Invasive Exercise Hemodynamic Evaluation in LVAD Patients

David M Kaye, MD, PhD, Alfred Hospital, Melbourne, Australia

**7:10 AM** _Q &A_

7:15 AM

Factors Influencing Exercise Performance in LVAD Patients

Stuart D. Russell, MD, Johns Hopkins Hospital, Baltimore, MD, USA

**7:25 AM** _Q &A_

7:30 AM

Pulsatility and Exercise Performance in Continuous vs. Pulsatile Flow

Christopher S Hayward, MD, St. Vincent's Hospital, Sydney, Australia

**7:40 AM** _Q &A_

7:45 AM

Right Ventricular Function During Exercise in LVAD Patients

Finn Gustafsson, MD, PhD, Rigshospitalet, Copenhagen, Denmark

**7:55 AM** _Q &A_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 02: Chagasic Cardiomyopathy: Lessons To Be Learned

Location:

Grand Hall B

Target Audience:

HF, HTX, ID, MCS

**Chairs:**

Alejandro M Bertolotti, MD, and Stanley Martin, MD

**Session Summary:** The cardiac form of Chronic Chagas Disease is responsible for inability to work, low quality of life and death among infected individuals. Chagas disease currently affects approximately 8 – 11 million people in South America, Central America and Mexico, and approximately 80 million people are at risk for contracting the illness. Although an estimated 300,000 persons with Chagas disease live in the USA, little is known about the burden of Chagasic heart disease. A 12-minute panel discussion with all speakers will conclude this session.

7:00 AM

Chronic Chagas Disease and Chagasic Cardiomyopathy

Anna K Sa, MD, Pro Cardiac Hospital, Rio de Janeiro, Brazil

7:12 AM

Arrhythmic Storm as the First and Last Manifestation of Chagas Disease

Fabiana G Marcondes-Braga, MD, PhD, Heart Institute, Sao Paulo, Brazil

7:24 AM

Heart Transplant in Chagasic Cardiomyopathy: How to Manage Immunosuppression

Fernando Bacal, MD, PhD, University of Sao Paulo, Sao Paulo, Brazil

7:36 AM

Reactivation of Chagas Post-Transplant: Diagnosis and Pharmaceutical Management

Lisa Peters, PharmD, MedStar Washington Hospital Center, Washington, DC, USA

**7:48 AM** _Panel Discussion_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 03: Lifecycle Journey of Thrombosis in Mechanical Circulatory Support Patients

Location:

Grand Hall C

Target Audience:

PHARM, HF, HTX, MCS, NHSAH

**Chairs:**

Stephan Schueler, MD, PhD, FRCS, and Christina T. Doligalski, PharmD, BCPS

**Session Summary:** This lifecycle journey is an enduring case with 3 defined points. The time points discussed include implantation and management strategies that influence thrombotic risk; management of anticoagulation including review of current therapy, potential novel therapies and appropriate monitoring; the anatomy of the clot and potential mechanisms of thrombosis in MCS.

7:00 AM

Lifecycle Journey Case Presentation

Christina T Doligalski, PharmD, BCPS, Tampa General Hospital, Tampa, FL, USA

7:03 AM

Influence of Surgical Techniques on Pump Thrombosis: How Physics Can Help Patient Management

Daniel Zimpfer, MD, Medical University of Vienna, Vienna, Austria

7:18 AM

Lifecycle Journey Case Update

Christina Doligalski

7:19 AM

Prevention of Thrombosis in Mechanical Support: Where are we going?

Ed Horn, PharmD, Allegheny General Hospital, Pittsburgh, PA, USA

7:34 AM

Lifecycle Journey Case Update

Christina Doligalski

7:35 AM

What Pathology Can Tell Us About Mechanisms of Thrombosis

Lisa Baumann Kreuziger, MD, Medical College of Wisconsin, Milwaukee, WI, USA

**7:50 AM** _Panel Discussion_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 04: Completing the Picture: Patient Reported Outcomes (PROs) as an Essential Source of Information in Evaluating Transplantation Outcomes

Location:

Grand Hall D

Target Audience:

NHSAH, ALL

**Chairs:**

Maria R. Molina, MSN, CRNP, CCRN, and James Kirklin, MD

**Session Summary:** Patient Reported Outcomes (PRO) are increasingly used to capture the outcomes of transplant recipients and living donors and have become an inherent part of the evaluation of transplant programs' quality assessment and performance improvement. PROs drive patient centered outcomes research (PCOR). The aim of this session is to explain the concept of patient reported outcomes, how PROs measures are developed and how PROs are assessed to successfully perform PCOR. Further it will provide a number of examples on the use of PROs in clinical practice, research, and quality assessment and performance.

7:00 AM

The Crucial Importance of PROs for Transplant Evaluation from a Clinical, Research and Quality Assurance Perspective

Linda Ohler, MSN, FAAN, George Washington University, Washington, DC, USA

**7:15 AM** _Q &A_

7:20 AM

State of the Art Development of PRO Assessments for Patient Centered Outcomes Research (PCOR)

Sabina M De Geest, RN, PhD, University of Basel, Basel, Switzerland

**7:35 AM** _Q &A_

7:40 AM

PROs in Pediatric Transplant Patients: Special Issues

Kathleen L Grady, PhD, APN, FAAN, Northwestern Memorial Hospital, Chicago, IL, USA

**7:55 AM** _Q &A_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 05: Upcoming Opportunities and Challenges in Pediatric Lung Transplantation

Location:

Seaport F-H

Target Audience:

PEDS, HF, LTX, MCS, PEDS, PH

**Chairs:**

Marc G. Schecter, MD, and Christian Benden, MD, FCCP

**Session Summary:** Over recent years, outcomes after lung transplantation in children have improved. Against this background, new challenges arise and new opportunities come up. At this symposium, selection criteria and bridging strategies to lung transplantation for critically ill neonates are discussed, and overall changing indications for pediatric lung transplantation given the decreasing number of children with cystic fibrosis referred for it. In addition, alternative approaches to lung transplant such as Potts-shunts in children with severe pulmonary arterial hypertension are reviewed, and strategies debated to increase the donor pool, for example ABO incompatible lung transplantation in smaller children.

7:00 AM

Bridge over Troubled Water: ECMO for the Critically Ill Newborn as a Bridging Strategy to Transplantation - Who is the Right Candidate?

Stuart C Sweet, MD, PhD, St. Louis Children's Hospital, St. Louis, MO, USA

**7:12 AM** _Q &A_

7:15 AM

New Kids on the Block: Is There a Change of Indications for Pediatric Lung and Heart-Lung Transplantation?

Bart L. Rottier, MD, University Medical Center Groningen, Groningen, Netherlands

**7:27 AM** _Q &A_

7:30 AM

ABO Incompatible Lung Transplantation in Infants and Small Children to Expand the Donor Pool: Where is the Age Limit and What Has To Be Considered?

Melinda P. Solomon, MD, FRCPC, Hospital for Sick Children, Toronto, ON, Canada

**7:42 AM** _Q &A_

7:45 AM

Potts-Shunt in Children with Severe PAH: A Promising Procedure To Avoid Lung Transplantation?

Maria C Gazzaneo, MD, Texas Children's Hospital, Houston, TX, USA

**7:57 AM** _Q &A_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 06: "Those Darn CARVs": Community Acquired Respiratory Viruses in Lung Transplant

Location:

Coronado A-C

Target Audience:

ID, LTX, PATH, PHARM

**Chairs:**

Pali Shah, MD, and Aric L Gregson, MD

**Session Summary:** Respiratory viruses following lung transplantation are a common occurrence and can range from the common cold to fulminant respiratory failure. Respiratory viruses have also been implicated in the development of Chronic Lung Allograft Dysfunction (CLAD), the most significant cause of mortality following lung transplantation. Available therapies are limited, however, as is the data supporting their use. Improved understanding of the host response to respiratory viruses may help contribute to the novel therapeutics.

7:00 AM

Respiratory Viruses and CLAD: Epidemiology and Clinical Data

Erika Lease, MD, University of Washington, Seattle, WA, USA

**7:10 AM** _Q &A_

7:15 AM

Respiratory Viruses and CLAD: Pathogenesis and Host Response

Tereza Martinu, MD, Toronto General Hosp/UHN, Toronto, ON, Canada

**7:25 AM** _Q &A_

7:30 AM

To Treat or Not to Treat: A Critical Review of Currently Available Therapies

Allan Glanville, MBBS, MD, FRACP, St. Vincent's Hospital, Sydney, Australia

**7:40 AM** _Q &A_

7:45 AM

In the Pipeline: Novel Therapeutics

Christopher Ensor, PharmD, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

**7:55 AM** _Q &A_

8:00 AM - 10:00 AM

## SYMPOSIUM 10: Antibodies in Mechanical Circulatory Support: The Phantom Menace

Location:

Seaport A-E

Target Audience:

MCS, BSTR, HF, HTX, PEDS, PHARM

**Chairs:**

Jon A. Kobashigawa, MD, and Andreas Zuckermann, MD

**Session Summary:** As the number of patients requiring mechanical circulatory support (MCS) increases, allosensitization in this population presents a special challenge as it limits options for transplantation. This session will discuss the nature of sensitization in MCS patients, epidemiology, risk of the sensitized MCS patient, therapeutic options and post-transplant management. A 20-minute panel discussion with all speakers will conclude this session.

8:00 AM

Is the MCS Device Immunomodulatory?

Elaine F Reed, PhD, UCLA Immunogenetics Center, Los Angeles, CA, USA

8:20 AM

Sensitization in the Pediatric MCS Population

Francesco Parisi, MD, Bambino Gesù Pediatric Hospital, Rome, Italy

8:40 AM

Approach to the Sensitized MCS Patient: Desensitization and Other Strategies

Jignesh K. Patel, MD, PhD, Cedars-Sinai Heart Institute, Los Angeles, CA, USA

9:00 AM

Epidemiology and Risk of the Sensitized MCS Patient

Michael Shullo, PharmD, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

9:20 AM

What Happens to the Antibodies After Heart Transplant?

Howard Eisen, MD, Drexel University, Philadelphia, PA, USA

**9:40 AM** _Panel Discussion_

8:00 AM - 10:00 AM

## SYMPOSIUM 11: Not CAVing to CLADtastrophy: Emerging Mechanisms of Chronic Heart and Lung Allograft Disease

Location:

Grand Hall A

Target Audience:

BSTR, HTX, LTX, PATH, PHARM

**Chairs:**

Elizabeth H Hammond, MD, and Christopher H. Wigfield, MD, FRCS

**Session Summary:** In this session, we will examine factors which have been recently implicated in coronary artery vasculopathy and chronic lung allograft dysfunction. Donor and recipient innate immune responses, autoimmune responses triggered by alloimmunity, and the pivotal role of endothelium and micro-vasculature will be explored. The goal of the session is to identify new pathologic and molecular targets for treatment in both Cardiac Allograft Vasculopathy (CAV) and Chronic Lung Allograft Dysfunction (CLAD). Importantly, this session will examin parallels between chronic processes in the transplanted heart and lung and bring together research and clinical experts in lung and heart transplantation.

8:00 AM

Pivotal Role of the Endothelium in CAV

Daniel Jane-Wit, MD, PhD, Yale School of Medicine, New Haven, CT, USA

**8:15 AM** _Q &A_

8:20 AM

Critical Effect of Airway Microvasculature on CLAD Development

Mark R. Nicolls, MD, Stanford University, Stanford, CA, USA

**8:35 AM** _Q &A_

8:40 AM

DAMPs, PAMPS and Innate Immunity in CAV

Joren C Madsen, MD, DPhil, Massachusetts General Hospital, Boston, MA, USA

**8:55 AM** _Q &A_

9:00 AM

DAMPs, PAMPs, and Innate Immunity in CLAD

Scott M. Palmer, MD, MHS, Duke University, Durham, NC, USA

**9:15 AM** _Q &A_

9:20 AM

Antibodies in CAV: the Role of Autoimmunity in Alloimmunity

Christine M Lin, MD, University of Colorado, Denver, CO, USA

**9:35 AM** _Q &A_

9:40 AM

Antibodies and B Cells in Pathogenesis of CLAD

Masaaki Sato, MD, University of Tokyo, Tokyo, Japan

**9:55 AM** _Q &A_

8:00 AM - 10:00 AM

## SYMPOSIUM 12: A Tale of Two Organs: Selecting and Managing Multi-Organ Transplant Recipients

Location:

Grand Hall B

Target Audience:

HTX, ALL

**Chairs:**

Teresa De Marco, MD, and Jose Gonzalez-Costello, MD

**Session Summary:** This session will use a combination of lectures and debates to highlight treatment options for patients who have primary thoracic organ failure and secondary end-organ dysfunction. Appropriate selection and management of multi-organ recipients will be discussed. In addition, speakers will address unique challenges faced in multi-organ transplantation, including a review of the policies and ethical considerations in allocating multiple organs to a single individual. A 15-minute panel discussion will conclude this session.

8:00 AM

Heart-Lung Transplantation: How Bad Do The Ventricles Have To Be?

John J Dunning, FRCS, Papworth Hospital, Cambridge, United Kingdom

8:15 AM

DEBATE (PRO): Heart Transplant Candidates with Vulnerable Kidneys Should Undergo Combined Heart-Kidney Transplantation

Eugene C DePasquale, MD, UCLA David Geffen School of Medicine, Los Angeles, CA, USA

8:30 AM

DEBATE (CON): Heart Transplant Candidates with Vulnerable Kidneys Should Undergo Combined Heart-Kidney Transplantation

Marcelo Cantarovich, MD, McGill University Health Centre, Montreal, QC, Canada

8:45 AM

DEBATE (PRO): Heart Transplant Candidates with Bridging Fibrosis Should Undergo Combined Heart-Liver Transplantation

Sudhir S Kushwaha, MD, Mayo Clinic, Rochester, MN, USA

9:00 AM

DEBATE (CON): Heart Transplant Candidates with Bridging Fibrosis Should Undergo Combined Heart-Liver Transplantation

Charles E. Canter, MD, St Louis Children's Hospital, St. Louis, MO, USA

9:15 AM

Thoracic and Abdominal Tug of War: Management of the Multi-Organ Transplant Recipient

Richard C Daly, MD, Mayo Clinic, Rochester, MN, USA

9:30 AM

Ethical Principles in Allocating Multiple Organs to One Recipient

Heather J Ross, MD, MHSc, FRCPC, Toronto General Hospital, Toronto, ON, Canada

**9:45 AM** _Panel Discussion_

8:00 AM - 10:00 AM

## SYMPOSIUM 13: Lung Allocation Scores (LAS): Making the Complex Simple, or Just the Simple Complex?

Location:

Grand Hall C

Target Audience:

LTX, ALL

**Chairs:**

Kevin M. Chan, MD, and Allan Glanville, MBBS, MD, FRACP

**Session Summary:** This symposium highlights the lung allocation systems employed worldwide, describes changes in US lung allocation since the implementation of the LAS, reviews the results of the LAS by Eurotransplant, describes early results of the LAS revision, and discusses controversies on allocation equality raised by the LAS.

8:00 AM

Who Needs LAS Anyway? Lung Allocation Around the World

Are Martin Holm, MD, Oslo University Hospital, Oslo, Norway

**8:20 AM** _Q &A_

8:24 AM

Lung Allocation Score: the Changing Landscape of Lung Transplantation in the USA

Thomas M. Egan, MD, MSC, University of North Carolina School of Medicine, Chapel Hill, NC, USA

**8:44 AM** _Q &A_

8:48 AM

Modification of the USA LAS Model 2015: Early Results

Kevin M Chan, MD, University of Michigan, Ann Arbor, MI, USA

**9:08 AM** _Q &A_

9:12 AM

LAS in Eurotransplant: Towards a Uniform Approach?

Jacqueline Smits, MD, PhD, Eurotransplant International Foundation, Leiden, Netherlands

**9:32 AM** _Q &A_

9:36 AM

LAS Controversies: Improving Equity in Organ Allocation?

Selim Arcasoy, MD, MPH, Columbia University, New York, NY, USA

**9:56 AM** _Q &A_

8:00 AM - 10:00 AM

## SYMPOSIUM 14: Chronic Thromboembolic Pulmonary Hypertension (CTEPH): Current Controversies and New Directions

Location:

Grand Hall D

Target Audience:

PH

**Chairs:**

William Auger, MD, and C. Dario Vizza, MD

**Session Summary:** This symposium will review some of the key questions and controversial topics in patients with CTEPH in the preoperative and postoperative period.

8:00 AM

Out-of-Proportion Pulmonary Vascular Resistance (PVR): Operative Suitability and Perioperative Considerations

Marc de Perrot, MD, University of Toronto, Toronto, ON, Canada

**8:15 AM** _Q &A_

8:20 AM

Medical Therapy for CTEPH as "Bridge" to Surgery: Right or Wrong?

Manreet Kanwar, MD, Allegheny General Hospital, Pittsburgh, PA, USA

**8:35 AM** _Q &A_

8:40 AM

The Right Ventrical (RV) in CTEPH: How to Assess Before and After Pulmonary Endarterectomy

Paul Forfia, MD, Temple University, Philadelphia, PA, USA

**8:55 AM** _Q &A_

9:00 AM

Chronic Thromboembolic Disease Without PH at Rest: Treat or Not?

John Granton, MD, University of Toronto, Toronto, ON, Canada

**9:15 AM** _Q &A_

9:20 AM

Residual PH after Pulmonary Endarterectomy (PEA): What Definition Should We Use?

Joanna Pepke-Zaba, MD, Papworth Hospital, Cambridge, United Kingdom

**9:35 AM** _Q &A_

9:40 AM

Is Balloon Pulmonary Angioplasty (BPA) an Alternative or Complementary to PEA?

Hiromi Matsubara, MD, PhD, Okayama Medical Center, Okayama, Japan

**9:55 AM** _Q &A_

8:00 AM - 10:00 AM

## SYMPOSIUM 15: HLA, AMR and DSA - Approaching Antibodies in Kids

Location:

Seaport F-H

Target Audience:

ALL

**Chairs:**

Steven A. Webber, MBChB, and Robert G. Weintraub, FRACP, FACC

**Session Summary:** The goal of this symposia is to educate transplant clinicians in the use of antibody testing in the assessment of patients who are candidates for transplant, and for assessment and treatment of Antibody Mediated Rejection (AMR) after transplant. The session will start with basic science background principles in HLA antibodies, and end with a case of an allosensitized patient, with a forum discussion by the experts.

8:00 AM

Back to the Basics: HLA Antibodies, Donor-Specific Antibodies, and How to Measure Them

Anat Roitberg-Tambur, DMD/PhD, Northwestern University, Chicago, IL, USA

**8:15 AM** _Q &A_

8:20 AM

Before Transplant: Why the PRA Matters

Anne Dipchand, MD, Hospital for Sick Children, Toronto, ON, Canada

**8:35 AM** _Q &A_

8:40 AM

Before Transplant: Why the PRA Doesn't Matter Anymore

Brian Feingold, MD, Children's Hospital of Pittsburgh, Pittsburgh, PA, USA

**8:55 AM** _Q &A_

9:00 AM

After Transplant: What To Do With New DSA?

Matthew Fenton, MRCPCH, Great Ormond Street Hospital for Children, London, United Kingdom

**9:15 AM** _Q &A_

9:20 AM

After Transplant: How to Diagnose and Treat AMR in Kids

Melanie D. Everitt, MD, Children's Hospital Colorado, Aurora, CO, USA

**9:35 AM** _Q &A_

9:40 AM

Case Presentation: Managing an Allosensitized Patient to Transplant

Ching Kit Chen, MBBS, MRCPCH, KK Women's and Children's Hospital, Singapore, Singapore

**9:50 AM** _Panel Discussion_

8:00 AM - 10:00 AM

## SYMPOSIUM 16: "Around the World in 80 Days": Infectious Challenges in Cardiothoracic Transplantation

Location:

Coronado A-C

Target Audience:

ID, HF, HTX, LTX

**Chairs:**

Saima Aslam, MD, MS, and Shahid Husain, MD, MS

**Session Summary:** The rise of cardiothoracic (CT) transplantation in emerging countries has led to unique infectious challenges. The goal of the symposium is to understand the impact of locally endemic infections such as Zika virus, hepatitis B, and tuberculosis on CT transplant recipients in different areas of the world. The presentations will cover the scope of the problem, management strategies, outcomes and travel advice.

8:00 AM

Perspective on Zika Virus and Other Emerging Infections from Latin America

Silvia V Campos, MD, Heart Institute of Sao Paulo Medical School, Sao Paulo, Brazil

**8:20 AM** _Q &A_

8:24 AM

Hepatitis B and Thoracic Transplantation

Emily A Blumberg, MD, Hospital of the University of Pennsylvania, Philadelphia, PA, USA

**8:44 AM** _Q &A_

8:48 AM

Screening and Management of Latent Tuberculosis

Subramanian Swaminathan, MD, MNAMS, Global Hospitals, Chennai/Bengaluru, India

**9:08 AM** _Q &A_

9:12 AM

Treatment of Tuberculosis

Amparo Sole, MD, PhD, Hospital Universitario la Fe, Valencia, Spain

**9:32 AM** _Q &A_

9:36 AM

Travel Advice for the Immunocompromised Traveler: Prophylaxis, Vaccination, and Other Preventive Measures

Stephanie Pouch, MD, The Ohio State University, Columbus, OH, USA

**9:56 AM** _Q &A_

10:30 AM - 12:30 PM

## PLENARY SESSION

Location:

Seaport A-E

Target Audience:

ALL

**Chairs:**

Hermann Reichenspurner, MD, PhD, and David O. Taylor, MD

10:30 AM

Putting an End to Transplantation? Translating the Promise of Stem Cell Therapy into Practice

Brenda Ogle, PhD, University of Minnesota, Minneapolis, MN, USA

**10:50 AM** ( **147)** Impella RP Post Approval Study: First Multi-Center, Prospective Post Market Approval Results for the Impella RP in Patients with Right Ventricular Failure; __ M. Anderson1, L. Morris1, D. Tang2, G. Batsides3, A. Kirtane4, I. Hanson5, P. Meraj6, N. Kapur7, W. O'Neill8. 1 _Einstein Healthcare Network, Philadelphia, PA,_ 2 _Virginia Commonwealth University, Richmond, VA,_ 3 _Rutgers / Robert Wood Johnson, New Brunswick, NJ,_ 4 _Columbia Presbyterian University Hospital, New York, NY,_ 5 _William Beaumont, Royal Oak, MI,_ 6 _Northwell Health, Manhasset, NY,_ 7 _Tufts University, Boston, MA,_ 8 _Henry Ford, Detroit, MI_

11:05 AM

Interactive Discussant

Martin Strueber, MD, MSU College of Human Medicine, East Lansing, MI, USA

11:10 AM

Tweets, Texts, and Posts: Does Social Media Improve or Complicate Communication in Medicine?

Dorry Segev, MD, PhD, Johns Hopkins School of Medicine, Baltimore, MD, USA

11:30 AM

Share and Share Alike: Optimizing Organ Allocation in an Era of Increasing Need

Sommer Gentry, PhD, USA Naval Academy, Annapolis, MD, USA

**11:50 AM** ( **148)** Early Graft Injury Measured by Donor-Derived Cell-Free DNA Predicts Early Mortality in Lung Transplant Recipients; __ S. Agbor-Enoh1, I. Tunc2, I. De Vlaminck3, A. Davis1, S. Gorham1, M. Jang1, K. Cuttin1, U. Fideli1, A. Marishta1, J. Wylie4, H. Luikart5, K. Khush4, H. Valantine1. 1 _Laboratory of Transplant Genomics, National Heart, Lung and Blood Institute, Bethesda, MD,_ 2 _Informatics and Computation Biology Core, National Heart, Lung and Blood Institute, Bethesda, MD,_ 3 _Cornell University, Itheca, NY,_ 4 _Stanford University School of Medicine, Palo Alto, CA,_ 5 _Laboratory of Transplant Genomics, Stanford University School of Medicine, Palo Alto, CA_

12:05 PM

Interactive Discussant

Erik Verschuuren, MD, PhD, University Medical Centre Groningen, Groningen, Netherlands

12:10 PM

Metabolomics: New Tools to Understand Rejection

Brendan Keating, PhD, Hospital of the University of Pennsylvania, Philadelphia, PA, USA

2:00 PM - 3:30 PM

## ORAL SESSION 13: Contemporary LVAD Trials - Same Old Song or New Tune?

Location:

Seaport A-E

Target Audience:

MCS, HF, HTX, NHSAH

**Chairs:**

Jeffrey J Teuteberg, MD, and Francis D Pagani, MD, PhD

**2:00 PM** ( **149)** Hemocompatibility Related Outcomes in the Multicenter Study of Maglev Technology in Patients Undergoing Mechanical Circulatory Support Therapy with Heartmate 3 (Momentum 3) Pivotal Trial; __ N. Uriel1, P. C. Colombo2, J. Cleveland3, J. Long4, C. T. Salerno5, D. Goldstein6, C. Patel7, G. Ewald8, A. J. Tatooles9, S. Silvestry10, R. John11, C. Caldeira12, V. Jeevanandam1, A. J. Boyle13, K. S. Sundareswaran14, P. Sood15, M. R. Mehra16. 1 _University of Chicago Medical Center, Chicago, IL,_ 2 _Columbia University Medical Center, New York, NY,_ 3 _University of Colorado Medical Center, Denver, CO,_ 4 _Integris Baptist Medical Center, Oklahoma City, OK,_ 5 _St.Vincents Hospital, Indianapolis, IN,_ 6 _Montefiore Medical Center, Bronx, NY,_ 7 _Duke University Medical Center, Durham, NC,_ 8 _Washington University School of Medicine, St.Louis, MO,_ 9 _Advocate Christ Medical Center, Chicago, IL,_ 10 _Florida Hospital, Orlando, FL,_ 11 _University of Minnesota Medical Center, Minneapolis, MN,_ 12 _Tampa General Hospital, Tampa, FL,_ 13 _Thomas Jefferson University, Philadelphia, PA,_ 14 _St.Jude Medical, Pleasanton, CA,_ 15 _St.Jude Medical, Burlington, MA,_ 16 _Brigham and Women's Hospital, Boston, MA_

**2:15 PM** ( **150)** ENDURANCE Destination Therapy Trial Outcomes as Stratified by Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) Classification; __ S. V. Pamboukian1, F. D. Pagani2, J. J. Teuteberg3, R. L. Kormos3, C. C. Caldeira4, C. H. Selzmann5, J. K. Kirklin1, B. B. Reid6, E. C. McGee7, C. A. Milano8, J. G. Rogers8. 1 _University of Alabama at Birmingham, Birmingham, AL,_ 2 _University of Michigan Medical Center, Ann Arbor, MI,_ 3 _University of Pittsburgh Medical Center, Pittsburgh, PA,_ 4 _Tampa General Hospital, Tampa, FL,_ 5 _University of Utah, Salt Lake City, UT,_ 6 _Intermountain Heart Institute, Murray, UT,_ 7 _Loyola University Medical Center, Maywood, IL,_ 8 _Duke University Medical Center, Durham, NC_

**2:30 PM** ( **151)** HeartMate 3 Fully Magnetically Levitated Left Ventricular Assist Device for the Treatment of Advanced Heart Failure - CE Mark Study 2-Year Results; __ J. D. Schmitto1, Y. Pya2, D. Zimpfer3, T. Krabatsch4, J. Garbade5, V. Rao6, M. Morshuis7, F. Beyersdorf8, S. Marasco9, P. Sood10, L. Damme10, I. Netuka11. 1 _Hannover Medical School, Hannover, Germany,_ 2 _National Research Cardiac Surgery Center, Astana, Kazakhstan,_ 3 _University of Vienna, Vienna, Austria,_ 4 _German Heart Center, Berlin, Germany,_ 5 _Heart Center Leipzig, Leipzig, Germany,_ 6 _Toronto General Hospital, Toronto, ON, Canada,_ 7 _Thoracic and Cardiovascular Surgery Clinic, Bad Oeynhausen, Germany,_ 8 _University Heart Center Freiburg-Bad Krozingen, Freiburg, Germany,_ 9 _The Alfred Hospital, Melbourne, Australia,_ 10 _St. Jude Medical Inc., St. Paul, MN,_ 11 _Institute for Clinical and Experimental Medicine, Prague, Czech Republic_

**2:45 PM** ( **152)** A Prospective, Controlled, Un-Blinded, Multi-Center Clinical Trial to Evaluate the Thoracotomy Implant Technique of the HVAD System in Patients with Advanced Heart Failure: Results of the LATERAL Trial; __ M. R. Danter1, E. C. McGee2, M. Strueber3, S. Maltais4, N. A. Mokadam5, G. M. Weisenthaler6, K. Leadley7, S. W. Boyce8, A. Cheung9. 1 _Vanderbilt University Medical Center, Nashville, TN,_ 2 _Loyola University Medical Center, Maywood, IL,_ 3 _Spectrum Health, Grand Rapids, MI,_ 4 _Mayo Clinic, Rochester, MN,_ 5 _University of Washington, Seattle, WA,_ 6 _University of California San Francisco, San Francisco, CA,_ 7 _HeartWare, Framingham, MA,_ 8 _MedStar Health, Washington, DC,_ 9 _University of British Columbia, Vancouver, BC, Canada_

**3:00 PM** ( **153)** Quality of Life and Functional Capacity Assessment in the Multicenter Study of Maglev Technology in Patients Undergoing Mechanical Circulatory Support Therapy with Heartmate 3(Momentum 3) Pivotal Trial; __ J. A. Cowger1, Y. Naka2, K. Aaronson3, D. Horstmanshoff4, S. Gulati5, D. Rinde-Hoffman6, S. Pinney7, S. Adatya8, D. J. Farrar9, U. P. Jorde10. 1 _St.Vincents Hospital, Indianapolis, IN,_ 2 _Columbia University Medical Center, New York, NY,_ 3 _University of Michigan Medical Center, Ann Arbor, MI,_ 4 _Integris Baptist Medical Center, Oklahoma City, OK,_ 5 _Carolinas Medical Center, Charlotte, NC,_ 6 _Tampa General Hospital, Tampa, FL,_ 7 _Mt.Sinai Hospital, New York, NY,_ 8 _University of Chicago Medical Center, Chicago, IL,_ 9 _St.Jude Medical, Pleasanton, CA,_ 10 _Montefiore Medical Center, Bronx, NY_

**3:15 PM** ( **154)** Impact of Adherence to Standard Practice Guidelines for Patients Receiving a Left Ventricular Assist Device - Insights from the PREVENT Study; __ J. N. Katz1, S. Emani2, G. Egnaczyk3, E. Adler4, J. Chin5, P. Shah6, A. Brieke7, M. Keebler8, S. Nathan9, I. Gregoric9, D. Crandall10, D. J. Farrar10, K. S. Sundareswaran10, S. Maltais11. 1 _Division of Cardiology, University of North Carolina, Chapel Hill, NC,_ 2 _Division of Cardiovascular Medicine, Ohio State University Medical Center, Columbus, OH,_ 3 _Christ Hospital, Cincinnati, OH,_ 4 _Division of Cardiovascular Medicine, University of California - San Diego, San Diego, CA,_ 5 _Sutter Medical Center, Sacramento, CA,_ 6 _Inova Heart and Vascular Institute, Falls Church, VA,_ 7 _University of Colorado School of Medicine, Denver, CO,_ 8 _Vanderbilt Heart and Vascular Institute, Vanderbilt University, Nashville, TN,_ 9 _Memorial Hermann – Texas Medical Center, Houston, TX,_ 10 _St. Jude Medical, Pleasanton, CA,_ 11 _Division of Cardiovascular Surgery, Mayo Clinic, Rochester, MN_

2:00 PM - 3:30 PM

## ORAL SESSION 14: Measure for Measure: In- and Ex-Vivo Cellular and Molecular Approaches for Thoracic Organ Tailoring

Location:

Grand Hall A

Target Audience:

BSTR, HF, HTX, LTX, MCS, NHSAH, PATH, PEDS, PHARM

**Chairs:**

Simon Pecha, MD, and Lori J West, MD, DPhil

**2:00 PM** ( **155)** Advanced Theranostics in Ex-Vivo Lung Bioengineering; __ B. A. Guenthart1, J. D. O'Neill2, J. Kim2, G. Vunjak-Novakovic3, M. Bacchetta1. 1 _Thoracic Surgery, Columbia University, New York, NY,_ 2 _Biomedical Engineering, Columbia University, New York, NY,_ 3 _Biomedical Engineering & Medicine, Columbia University, New York, NY_

**2:15 PM** ( **156)** Mesenchymal Stem Cell Therapy for Ex Vivo Repair of Ischemic Injury in Pig Donor Lungs; __ D. Nakajima1, Y. Watanabe1, A. Ohsumi1, M. Pipkin1, M. Chen1, P. Mordant1, T. Kanou1, G. Zehong1, R. Lam1, R. Coutinho1, L. Caldarone1, R. K. Lyer2, J. E. Davies2, T. K. Waddell1, M. Cypel1, M. Liu1, S. Keshavjee1. 1 _Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, University of Toronto, Toronto, ON, Canada,_ 2 _Tissue Regeneration Therapeutics Inc, Toronto, ON, Canada_

**2:30 PM** ( **157)** Hypoxia Inducible Factor 1 Alpha Mediates Apoptotic Cell Death in the DCD Heart Following Prolonged Exposure to Warm Ischemia; __ A. A. Ali1, P. Downey2, A. Zalewski2, K. J. Clerkin2, I. George3, P. C. Colombo2, S. Messer1, S. R. Large1, Z. A. Ali2. 1 _Cardiothoracic Surgery, Papworth Hospital, Cambridge, United Kingdom,_ 2 _Cardiology, Columbia University, New York, NY,_ 3 _Cardiothoracic Surgery, Columbia University, New York, NY_

**2:45 PM** ( **158)** Extending the Boundaries of DCD Heart Transplantation: Improved Functional Recovery of DCD Hearts Exposed to Prolonged Warm Ischemia by Inhibition of Histone Deacetylase; __ A. A. Ali1, P. Downey2, A. Zalewski2, K. J. Clerkin2, I. George3, P. C. Colombo2, S. Messer1, S. Large1, Z. A. Ali2. 1 _Cardiothoracic Surgery, Papworth Hospital, Cambridge, United Kingdom,_ 2 _Cardiology, Columbia University, New York, NY,_ 3 _Cardiothoracic Surgery, Columbia University, New York, NY_

**3:00 PM** ( **159)** Donor Organ Pretreatment with a Gap and Tight Junction Stabilizing Peptide Prevents IRI in a Mouse Lung Transplant Model; __ Q. Cheng1, K. Patel1, P. Zhu2, L. Rucker1, P. Allen1, C. Vasu1, S. Nadig1, C. Atkinson1. 1 _Departments of Microbiology and Immunology, and Surgery, Medical University of South Carolina, Charleston, SC,_ 2 _Department of Surgery, Tongji Hospital, Wuhan, China_

**3:15 PM** ( **160)** Normothermic Donor Lung Preservation Using the Organ Care System Significantly Reduces Ischemia/Reperfusion Injury by Promoting Cytokine Antagonists; __ B. Wiegmann1, C. Falk2, M. Seyda2, C. Neudoerfl2, C. Kühn1, I. Tudorache1, M. Avsar1, A. Haverich1, G. Warnecke1. 1 _Dpt. for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany,_ 2 _Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany_

2:00 PM - 3:30 PM

## ORAL SESSION 15: Therapies and Monitoring After Heart Transplantation

Location:

Grand Hall B

Target Audience:

HTX, BSTR, NHSAH, PHARM

**Chairs:**

Todd F Dardas, MD, and Mustafa Toma, MD

**2:00 PM** ( **165)** Metformin Treatment After Heart Transplantation Is Associated with Reduced Malignancy Rate; __ Y. Peled1, J. Lavee1, E. Raichlin2, M. Katz1, M. Arad1, Y. Shemesh1, Y. Kassif1, E. Asher1, D. Elian1, Y. Har-Zahav1, N. Shlomo1, D. Freimark1, I. Goldenberg1, R. Klempfner1. 1 _Sheba Medical Center and Tel Aviv University, Tel Aviv, Israel,_ 2 _University of Nebraska Medical Center, Omaha, NE_

**2:15 PM** ( **162)** High Sensitivity Troponin Assays Can Decrease the Frequency of Endomyocardial Biopsy After Heart Transplantation; __ S. Fitzsimons1, J. Parameshwar1, N. Mills2, S. Pettit1. 1 _Transplant Unit, Papworth Hospital, Papworth, United Kingdom,_ 2 _BHF Centre for Cardiovascular Sciences, Royal Infirmatory of Edinburgh, Edinburgh, United Kingdom_

**2:30 PM** ( **163)** Cluster Analysis and Dynamic Phenomapping to Guide Clinical Management After Heart Transplantation; __ M. Bakir, N. Jackson, S. Han, C. Tseng, E. Chang, T. Khuu, A. Bui, Q. Zhang, E. Reed, D. Liem, B. Kubak, J. Schaenman, A. Ardehali, R. Ardehali, A. Baas, A. Nsair, D. Cruz, M. Kwon, E. DePasquale, M. Deng, M. Cadeiras. _Cardiology, UCLA, Los Angeles, CA_

**2:45 PM** ( **164)** Effect of Donor Simvastatin Treatment on Cardiac Allograft Ischemia-Reperfusion Injury - 30-Day Analysis of a Randomized Prospective Single-Center Clinical Trial; __ A. I. Nykanen1, E. Holmström2, S. Syrjälä2, J. Jokinen1, R. Krebs2, K. B. Lemström1. 1 _Cardiac Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland,_ 2 _University of Helsinki, Helsinki, Finland_

**3:00 PM** ( **161)** Analysis of Donor-Derived Cell-Free DNA with 3-Year Outcomes in Heart Transplant Recipients; __ M. Crespo-Leiro1, D. Hiller2, R. Woodward2, M. Grskovic2, C. Marchis2, M. Song2, J. Collins2, A. Zuckermann3. 1 _Hospital Universitario de A Coruña, La Coruña, Spain,_ 2 _CareDx, Brisbane, CA,_ 3 _Medical University of Vienna, Vienna, Austria_

**3:15 PM** ( **166)** Does Induction Therapy for Heart Transplant Recipients on Tacrolimus/Mycophenolate/Prednisone Improve Survival in the Current Allocation Era?; __ A. A. Amin1, V. K. Ariyamuthu2, M. A. Urey1, F. G. Araj1, M. H. Drazner1, P. P. Mammen1, B. Tanriover2. 1 _Cardiology, UT Southwestern, Dallas, TX,_ 2 _Nephrology, UT Southwestern, Dallas, TX_

2:00 PM - 3:30 PM

## ORAL SESSION 16: The Rise of the Machines: ECLS and EVLP in Lung Transplantation

Location:

Grand Hall C

Target Audience:

LTX, BSTR, EEP, ID, LTX, MCS, NHSAH, PATH, PHARM

**Chairs:**

Goran Dellgren, MD, PhD, and Marc De Perrot, MD

**2:00 PM** ( **167)** ECLS Bridge to Lung Transplantation: A Review of Our Institutional Experience; __ A. Benazzo, G. Tukora, S. Schwarz, K. Hoetzenecker, B. Moser, J. Matilla Sigueenza, S. Taghavi, P. Jaksch, W. Klepetko, G. Lang. _Thoracic Surgery, Medical University of Vienna, Vienna, Austria_

**2:15 PM** ( **168)** ECMO Prior to Lung Transplantation Does Not Impact Health-Related Quality of Life (HRQL) After Transplant; __ N. A. Kolaitis, D. Huang, A. Soong, P. Shrestha, J. Golden, L. E. Leard, R. J. Shah, M. E. Kleinhenz, J. R. Greenland, P. P. Katz, P. D. Blanc, S. R. Hays, J. Kukreja, J. P. Singer. _University of California, San Francisco, San Francisco, CA_

**2:30 PM** ( **169)** Enhanced Organ Procurement with Resuscitation of Highly Marginal Donors with the Vivoline Ex Vivo Lung Perfusion System; __ C. Divithotawela, D. C. Chambers, S. Yerkovich, P. Hopkins. _Queensland Lung Transplant Service, The Prince Charles Hospital, Chermside, Australia_

**2:45 PM** ( **170)** Treatment oh Hepatitis C in Donor Lungs Using Ex Vivo Lung Perfusion; __ M. Galasso, M. Pipkin, Y. Watanabe, D. Nakajima, C. Summers, R. Qaquish, A. Ali, A. Ohsumi, A. Gazzalle, T. K. Waddell, M. Liu, S. Keshavjee, M. Cypel. _Latner Thoracic Surgery Laboratories, University Health Network, Toronto, ON, Canada_

**3:00 PM** ( **171)** Improved Outcomes with Negative Pressure Ventilation (NPV) During Normothermic Ex Vivo Lung Perfusion; __ N. Aboelnazar1, S. Himmat1, S. Hatami1, C. W. White2, D. H. Freed3, J. Nagendran3. 1 _Experimental Surgery, University of Alberta, Edmonton, AB, Canada,_ 2 _Cardiac Surgery Resident, University of Alberta, Edmonton, AB, Canada,_ 3 _Division of Cardiac Surgery, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada_

**3:15 PM** ( **172)** High Levels of Cytokines in the Perfusate During Ex-Vivo Lung Perfusion Correlates with Persistence of Poor Graft Function After Lung Transplantation Using Reconditioned Grafts; __ M. Boffini, V. Fanelli, E. Simonato, D. Ricci, P. Solidoro, P. Lausi, C. Barbero, L. Brazzi, M. Rinaldi. _Surgical Sciences Department, University of Turin, Turin, Italy_

2:00 PM - 3:30 PM

## ORAL SESSION 17: What's Up Next in Pulmonary Hypertension Research?

Location:

Grand Hall D

Target Audience:

PH, BSTR, HF, LTX

**Chairs:**

Dana P McGlothlin, MD, and David L Joyce, MD

**2:00 PM** ( **173)** Human Right Ventricular Myofilaments Exhibit Directionally Opposite Changes in Maximal Force and Calcium Sensitivity in Systemic Sclerosis-Associated versus Idiopathic Pulmonary Arterial Hypertension; __ S. Hsu1, J. A. Kirk2, C. J. Mullin3, M. Mukherjee1, T. M. Kolb3, R. L. Damico3, S. C. Mathai3, A. A. Shah4, F. M. Wigley4, K. B. Margulies5, P. M. Hassoun3, R. J. Tedford1, D. A. Kass1. 1 _Cardiology, Johns Hopkins University, Baltimore, MD,_ 2 _Cell and Molecular Physiology, Loyola University Chicago Stritch School of Medicine, Chicago, IL,_ 3 _Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD,_ 4 _Rheumatology, Johns Hopkins University, Baltimore, MD,_ 5 _Cardiology, University of Pennsylvania School of Medicine, Philadelphia, PA_

**2:15 PM** ( **174)** In-Vivo Study of a Novel Long-Term Lung Support Device for PAH, Bridge-to-Transplant and Bridge-to-Candidacy; __ R. Borchardt1, S. Sonntag1, P. Ritter1, F. Boehning1, S. Groß-Hardt1, F. Hesselmann1, U. Steinseifer2, T. Verbelen3, B. Meyns3, T. Kaufmann1. 1 _enmodes GmbH, Aachen, Germany,_ 2 _Dept. of Cardiovascular Engineering, Institute of Applied Medical Engineering, RWTH Aachen University, Aachen, Germany,_ 3 _Dept. of Cardiovascular Science, KU Leuven, Leuven, Belgium_

**2:30 PM** ( **175)** Lung Allocation Score Is Not Predictive of Post-Transplant Survival Among Pulmonary Hypertension Lung Transplant Recipients; __ H. Maredia1, M. Bowring1, A. Massie1, S. Oyetunji1, C. Merlo2, R. Higgins1, D. Segev1, E. Bush1. 1 _Department of Surgery, Johns Hopkins University, Baltimore, MD,_ 2 _Department of Medicine, Johns Hopkins University, Baltimore, MD_

**2:45 PM** ( **176)** Surgical Series of 370 Cases of Pulmonary Thromboendarterectomy: Experience from the Indian Subcontinent; __ V. Shetty, J. Punnen, D. P. Shetty. _Cardiac Surgery, Narayana Institute of Cardiac Sciences, Bangalore, India_

**3:00 PM** ( **177)** Implications of PAP Changes from Right Heart Catheterization to Lung Transplantation; __ S. Biswas Roy1, R. Panchanathan2, E. Todd1, P. Kang3, R. Walia1, R. M. Bremner1, M. A. Smith4. 1 _Norton Thoracic Institute; St. Joseph's Hospital and Medical Center, Phoenix, AZ,_ 2 _University of Arizona Medical School, Phoenix, AZ,_ 3 _University of Arizona College of Public Health, Phoenix, AZ,_ 4 _Norton Thoracic Institute, Phoenix, AZ_

**3:15 PM** ( **178)** Incremental Benefit of Cardiopulmonary Exercise Testing for the Prediction of Outcome in Stable Prevalent Pulmonary Arterial Hypertension Patients; __ R. Badagliacca1, S. Papa1, R. Poscia1, G. Valli1, B. Pezzuto1, G. Manzi1, P. Palange2, F. Fedele1, C. D. Vizza1. 1 _Cardiovascular and Respiratory Science, Sapienza University of Rome, Rome, Italy,_ 2 _Clinical Medicine, Sapienza University of Rome, Rome, Italy_

2:00 PM - 3:30 PM

## ORAL SESSION 18: Contemporary Challenges in Pediatric Heart Transplant

Location:

Seaport F-H

Target Audience:

PEDS, HTX, PATH

**Chairs:**

Steven C Greenway, MD, and Tajinder P Singh, MD, MSc

**2:00 PM** ( **179)** Pediatric Marginal Donor Hearts: National Use and Center-Specific Variability; __ A. K. Morrison1, D. Tumin2, D. Hayes, Jr.3, C. Phelps1, J. Tobias2, R. J. Gajarski1, D. Nandi1. 1 _The Heart Center, Nationwide Children's Hospital, Columbus, OH,_ 2 _Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH, _3 _Section of Pulmonary Medicine, Nationwide Children's Hospital, Columbus, OH_

**2:15 PM** ( **180)** Hearts Transplanted After Circulatory Death in Children: Analysis of the International Society for Heart and Lung Transplantation Registry; __ J. Kleinmahon1, S. Patel1, S. Auerbach1, J. Stehlik2, J. Rossano3, M. Everitt1. 1 _Cardiology, Children's Hospital Colorado, Denver, CO,_ 2 _Cardiology, University of Utah Hospital, Salt Lake City, UT,_ 3 _Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA_

**2:30 PM** ( **181)** Use of Decellularized Cryopreserved Allografts During Single Ventricle Reconstruction Results in Lower HLA Sensitization Than Standard Allograft; __ H. M. Lim1, J. Friedland-Little2, S. Yu1, R. E. Lowery1, R. J. Gajarski3, R. G. Ohye4, K. R. Schumacher1. 1 _Department of Pediatric Cardiology, University of Michigan, C.S Mott Children's Hospital, Ann Arbor, MI,_ 2 _Department of Pediatric Cardiology, Seattle Children's Hospital, Seattle, WA,_ 3 _Department of Pediatric Cardiology, Nationwide Children's Hospital, Columbus, OH,_ 4 _Department of Cardiac Surgery, University of Michigan, C.S Mott Children's Hospital, Ann Arbor, MI_

**2:45 PM** ( **182)** Impact of Newly Detected Donor Specific Anti-HLA Antibody in the First Year After Pediatric Heart Transplantation; __ A. I. Dipchand1, S. Webber2, K. Much3, B. Feingold4, C. Bentlejewski5, E. D. Blume6, R. Shaddy7, C. Canter8, J. Lamour9, W. Mahle10, W. Zuckerman11, H. Diop12, Y. Morrison13, B. Armstrong3, D. Ikle3, J. Odim13, A. Zeevi14, T. CTOTC-04 Investigators13. 1 _Hosp for Sick Children, Toronto, ON, Canada,_ 2 _Vanderbilt Univ, Nashville, TN,_ 3 _Rho, Chapel Hill, NC,_ 4 _Children's Hospital of Pittsburgh, Pittsburgh, PA, Canada,_ 5 _Children's Hospital of Pittsburgh, Pittsburgh, PA,_ 6 _Children's Hospital Boston, Boston, MA, Canada,_ 7 _Children's Hospital of Philadelphia, Philadelphia, PA,_ 8 _St Louis Children's Hospital, St Louis, MO,_ 9 _Montefiore Children's Hospital, New York, NY,_ 10 _Children's Healthcare of Atlanta, Atlanta, GA,_ 11 _Children's Hospital of New York, New York, NY,_ 12 _NIAID, Bethesda, MD, Canada,_ 13 _NIAID, Bethesda, MD,_ 14 _Univ of Pittsburgh, Pittsburgh, PA_

**3:00 PM** ( **183)** HLA Eplet Mismatching Is Associated with Increased Risk of Graft Loss in Pediatric Heart Transplant Recipients; __ E. Albers1, N. Jorgensen2, J. Friedland-Little1, B. Hong1, M. Kemna1, P. Warner3, Y. Law1. 1 _Seattle Children's Hospital, Seattle, WA,_ 2 _University of Washington, Seattle, WA,_ 3 _Bloodworks Northwest, Seattle, WA_

**3:15 PM** ( **184)** Predicting Cardiac Allograft Vasculopathy Using Circulating Vascular Endothelial Growth Factor in Pediatric Heart Transplant Recipients; __ K. Watanabe, S. D. Miyamoto, S. J. Nakano. _School of Medicine, University of Colorado Denver, Aurora, CO_

2:00 PM - 3:30 PM

## ORAL SESSION 19: Junior Faculty Clinical Case Dilemmas in Thoracic Transplantation: The Best of the Best

Location:

Coronado A-C

Target Audience:

ALL

**Chairs:**

Duane Davis, MD, MBA, and Hirsch S Mehta, MD

**2:00 PM** ( **185)** Driving an Electric Car Before You're Old Enough To Get A Licence; __ D. S. Burstein1, D. Nandi2, J. W. Gaynor1, J. W. Rossano1. 1 _Pediatric Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA,_ 2 _Pediatric Cardiology, Nationwide Children's Hospital, Columbus, OH_

2:05 PM

Expert Senior Discussant (Pediatric Transplantation)

Elfriede Pahl, MD, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA

**2:09 PM** _Moderated Discussion_

**2:15 PM** ( **186)** Doing Your Best to Keep the Germs Away; __ T. Sam1, S. Wada2, S. M. Joseph3, J. F. Trotter1, S. K. Asrani1, B. Lima3, G. Gonzalez-Stawinski3, S. A. Hall3, R. L. Gottlieb3. 1 _Baylor Annette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center, Dallas, Dallas, TX,_ 2 _Transplant Infectious Diseases, Baylor University Medical Center, Dallas, Dallas, TX,_ 3 _Baylor Center for Advanced Heart and Lung Disease, Baylor University Medical Center, Dallas, Dallas, TX_

2:20 PM

Expert Senior Discussant (Infectious Diseases)

Stanley I. Martin, MD, Geisinger Health System, Danville, PA, USA

**2:24 PM** _Moderated Discussion_

**2:30 PM** ( **187)** When Phoning It In Becomes the New Normal; __ R. J. Cogswell1, T. B. Freitag1, C. A. Lilla2, R. John3. 1 _Cardiology, University of Minnesota, Minneapolis, MN,_ 2 _Nursing, Fairview - University of Minnesota Medical Center, Minneapolis, MN,_ 3 _Cardiovascular Surgery, University of Minnesota, Minneapolis, MN_

2:35 PM

Expert Senior Discussant (Mechanical Circulatory Support)

Daniel J. Goldstein, MD, Montefiore Medical Center, Bronx, NY, USA

**2:39 PM** _Moderated Discussion_

**2:45 PM** ( **188)** The Logistics of Staffing Clinic From Home; __ S. Airhart1, C. Walters1, N. Verlinden1, P. Correa1, V. Franco2, A. Raina1, R. Benza1. 1 _Allegheny General Hospital, Pittsburgh, PA,_ 2 _Ohio State University, Columbus, OH_

2:50 PM

Expert Senior Discussant (Pulmonary Hypertension)

Myung H. Park, MD, Houston Methodist, Houston, TX, USA

**2:54 PM** _Moderated Discussion_

**3:00 PM** ( **189)** Safety During a Transition of Power; __ Y. Peled, Y. Har-Zahav, Y. Kassif, Y. Shemesh, D. Freimark, J. Lavee. _Sheba Medical Center and Tel Aviv University, Tel Aviv, Israel_

3:05 PM

Expert Senior Discussant (Heart Failure/Transplantation)

Steven SL Tsui, MD, FRCS, Papworth Hosp NHS Trust, Cambridge, United Kingdom

**3:09 PM** _Moderated Discussion_

**3:15 PM** ( **190)** How It Feels to Get Rejected Quickly; __ G. L. Calligaro1, N. Watson2, M. Malouf1, M. Plit1, M. R. Qiu3, T. Shein3, M. Benzimra1, A. Rigby1, A. R. Glanville1, A. Havryk1. 1 _Lung Transplantation, St. Vincent's Hospital, Sydney, Australia,_ 2 _Tissue Typing Laboratory, Australian Red Cross, Sydney, Australia,_ 3 _Anatomical Pathology, St. Vincent's Hospital, Sydney, Australia_

3:20 PM

Expert Senior Discussant (Lung Failure/Transplantation)

Glen P. Westall, FRACP, PhD, Alfred Hospital, Melbourne, Australia

**3:24 PM** _Moderated Discussion_

4:00 PM - 6:00 PM

## SYMPOSIUM 17: To Pulse or Not To Pulse? That is the Question

Location:

Seaport A-E

Target Audience:

ALL

**Chairs:**

Paolo Colombo, MD, and Bart Meyns, MD, PhD

**Session Summary:** Human evolution has favored a pulsatile heart pump as the optimal way for organ perfusion. CF-LVAD physiology, with low to no pulsatility, has challenged that widely accepted notion. Although the present technology had been rapidly adapted, we are still hampered by morbidities that limit the expansion into the less sick group. Are we missing the pulse? Thus, methods to generate pulsatility and possibly create a hybrid between the man-made and mankind are presently being explored. A 15-minute panel discussion with all speakers will conclude this session.

4:00 PM

Physiologic and Clinical Impact of Pulsatile vs. Nonpulsatile Flow on Blood Vessels and Vital Organs

Nader Moazami, MD, Cleveland Clinic, Cleveland, OH, USA

4:15 PM

Physiologic and Clinical Impact of Pulsatile vs. Nonpulsatile Flow on the Brain

William K Cornwell, MD, University of Colorado, Denver, CO, USA

4:30 PM

Best Strategies to Measure Arterial Pulsatility and Tissue Perfusion in CF-LVAD Patients

Melana Yuzefpolskaya, MD, Columbia University, New York, NY, USA

4:45 PM

Design and Rationale for New Pulsatile Technology

Stephen C Koenig, PhD, University of Louisville, Louisville, KY, USA

5:00 PM

Hemodynamic Effects of Counterpulsation

Navin K Kapur, MD, Tufts Medical Center, Boston, MA, USA

5:15 PM

Long-term Ambulatory Counterpulsation Using iVAS

Val Jeevanandam, MD, University of Chicago Medicine, Chicago, IL, USA

5:30 PM

The Pulse of Life - A Scientific and Existential Perspective

Mandeep Mehra, MD, FRCP, FACC, FESC, Brigham and Women's Hospital / Harvard Medical School, Boston, MA, USA

**5:45 PM** _Panel Discussion_

4:00 PM - 6:00 PM

## SYMPOSIUM 18: Weeding Out Fact from Fiction - the Highs and Lows of Marijuana Use in Transplant

Location:

Grand Hall A

Target Audience:

PHARM, ALL

**Chairs:**

Adam Cochrane, PharmD, and Vincent G. Valentine, MD

**Session Summary:** Increasing prevalence of medicinal and recreational cannabis use among transplant recipients has sparked discussion on the legal and safety ramifications of cannabis use in this patient population. This symposium will discuss the pharmacology of cannabis as well as explore the data surrounding the legal ramifications and risk/benefits of cannabis use in transplantation.

4:00 PM

The Pharmacology of a Weed: Clinical Pharmacology of Cannabis and Cannabinoids

Robert L Page, PharmD, MSPH, University of Colorado, Denver, CO, USA

**4:15 PM** _Q &A_

4:20 PM

Cannabis: Wonder-Drug or Devil's Weed? The Psychosocial Impact of Cannabis Use Post-Transplant

Patrick Smith, PhD, Duke University Medical Center, Durham, NC, USA

**4:35 PM** _Q &A_

4:40 PM

Cannabis Use and Graft Function: What Do We Know?

Lianne G. Singer, MD, FRCPC, Toronto General Hospital, Toronto, ON, Canada

**4:55 PM** _Q &A_

5:00 PM

But the Government Says I Can⋯ Regulatory Implications of Legalizing Cannabis

Lorriana E Leard, MD, UCSF Medical Center, San Francisco, CA, USA

**5:15 PM** _Q &A_

5:20 PM

DEBATE (PRO): Cannabis Use Pre-Transplant - Don't Judge Me!

Martin Zamora, MD, University of Colorado, Denver, CO, USA

5:35 PM

DEBATE (CON): Cannabis Use Pre-Transplant - Don't Judge Me!

Erik Verschuuren, MD, PhD, University Medical Centre Groningen, Groningen, Netherlands

5:50 PM

DEBATE REBUTTAL (PRO)

Martin Zamora

5:55 PM

DEBATE REBUTTAL (CON)

Erik Am Verschuuren

4:00 PM - 6:00 PM

## SYMPOSIUM 19: Cardiogenic Shock: Types, Teams and Tactics

Location:

Grand Hall B

Target Audience:

HF, HTX, MCS

**Chairs:**

Lynn R Punnoose, MD, and Marian Urban, MD

**Session Summary:** Cardiogenic shock encompasses a broad clinical spectrum, including acute MI, primary RV failure and biventricular failure. This session will incorporate individual presentations describing (1) the spectrum and prevalence of cardiogenic shock subtypes, (2) national and international approaches to management and temporary mechanical support selection, and (3) the interdisciplinary approach to device management involving heart failure, interventional, critical care and imaging cardiologists.

4:00 PM

Phenotypes of Cardiogenic Shock: How to Move Beyond Anecdotes to Estimate Subtype Prevalence

Shelley A. Hall, MD, Baylor University Medical Center, Dallas, TX, USA

**4:15 PM** _Q &A_

4:20 PM

Hemodynamics of Temporary MCS: Do They Help Guide Device Selection? What If You Don't Have Them?

Gabriel Sayer, MD, University of Chicago, Chicago, IL, USA

**4:35 PM** _Q &A_

4:40 PM

The Use of SHOCK Teams in Hospitals with Advanced Heart Failure Care

Jose N Nativi, MD, University of Utah School of Medicine, Salt Lake City, UT, USA

**4:55 PM** _Q &A_

5:00 PM

Refractory Ventricular Tachycardia (VT) with Hemodynamic Compromise: Temporary Device Choice and Ablative Options

A Reshad Garan, MD, Columbia University, New York, NY, USA

**5:15 PM** _Q &A_

5:20 PM

Weaning Temporary Mechanical Circulatory Support: Echocardiographic vs. Hemodynamic Parameters - This Is How We Do It

Jamie L Kennedy, MD, University of Virginia Health System, Charlottesville, VA, USA

**5:35 PM** _Q &A_

5:40 PM

Weaning Temporary Mechanical Circulatory Support: Echocardiographic vs. Hemodynamic Parameters - This Is How WE Do It

Evgenij V Potapov, MD, PhD, Berlin Heart Center, Berlin, Germany

**5:55 PM** _Q &A_

4:00 PM - 6:00 PM

## SYMPOSIUM 20: ECMO in Lung Transplantation: Sensational Success or Fantastic Failure?

Location:

Grand Hall C

Target Audience:

LTX, ALL

**Chairs:**

Erika Berman Rosenzweig, MD, and Reda E. Girgis, MD

**Session Summary:** This symposium gives a state-of-the art overview of current ECMO technology, including cannulation strategies, patient selection, peri-operative and program management.

4:00 PM

ECMO Technique: Configuration, Cannulae, Complications

Martin Strueber, MD, Michigan State University College of Human Medicine, East Lansing, MI, USA

**4:20 PM** _Q &A_

4:24 PM

ECMO Candidate Selection for Elective ECMO

Clemens Aigner, MD, Universität Duisburg-Essen, Essen, Germany

**4:44 PM** _Q &A_

4:48 PM

ECMO as Urgent Bridge to Transplant

Gregor Warnecke, MD, Hannover Medical School, Hannover, Germany

**5:08 PM** _Q &A_

5:12 PM

Post-Operative ECMO for Rescue Therapy

Göran Dellgren, MD, Sahlgrenska University Hospital, Göteborg, Sweden

**5:32 PM** _Q &A_

5:36 PM

ECMO Program Management: Bridge over Troubled Water?

David Michael McMullan, MD, Seattle Children's Hospital, Seattle, WA, USA

**5:56 PM** _Q &A_

4:00 PM - 6:00 PM

## SYMPOSIUM 21: Cardiopulmonary Hemodynamics, the Right Ventricle, and the Kidney: Connecting All the Dots

Location:

Grand Hall D

Target Audience:

PH, HF, HTX, LTX, MCS

**Chairs:**

Ryan J Tedford, MD, and Marco Guazzi, MD, PhD

**Session Summary:** This symposium reviews hot topics in hemodynamic assessment and management of patients with pulmonary hypertension including measures of pulmonary vascular compliance, the emerging role of right ventricular reserve assessment, and the interaction between right heart and kidney function. In the final two talks, the speakers debate the need for provocative testing in patients meeting hemodynamic criteria for Group I PAH but who have all least some phenotypic characteristics of group II PH. A panel discussion with all speakers will conclude this session.

4:00 PM

Forget About Pulmonary Vascular Resistance (PVR), Only Pulmonary Vascular Compliance Matters

Thenappan Thenappan, MD, University of Minnesota, Minneapolis, MN, USA

4:20 PM

No Time to Rest: The Importance of Right Ventricular Reserve in Pulmonary Hypertension

Robert Naeije, MD, Université Libre de Bruxelles, Brussels, Belgium

4:40 PM

The Cardiorenal Syndrome in Right Heart Failure: Just Central Venous Pressure (CVP) or More to the Story?

Maria Rosa Costanzo, MD, Midwest Heart Specialists-Advocate Medical, Naperville, IL, USA

5:00 PM

Case Presentation: Age >65, mPAP>25mmHg, Borderline Pulmonary Artery Wedge Pressure (PAWP)

Rebecca Cogswell, MD, University of Minnesota, Minneapolis, MN, USA

5:05 PM

DEBATE (PRO): It is Essential to Unmask PH due to Left Heart Disease (LHD) with Volume Loading and/or Exercise Testing

Marc A. Simon, MD, University of Pittsburgh, Pittsburgh, PA, USA

5:25 PM

DEBATE (CON): It is Essential to Unmask PH due to Left Heart Disease (LHD) with Volume Loading and/or Exercise Testing

Susanna Mak, MD, PhD, Mount Sinai Hospital, Toronto, ON, Canada

**5:45 PM** _Panel Discussion_

4:00 PM - 6:00 PM

## SYMPOSIUM 22: Let's Get Personal! Precision Diagnostics in Thoracic Transplantation

Location:

Seaport F-H

Target Audience:

PATH, ALL

**Chairs:**

Patrick Bruneval, MD, and Sean Agbor-Enoh, MD

**Session Summary:** In recent years, methodologies of precision medicine have been applied to the study of post-transplant pathobiology. Basic molecular mechanisms involved in acute and chronic allograft rejection have been uncovered, and novel molecular tools for the non-invasive monitoring of heart and lung transplantation have been discovered. This symposium brings together state-of-the-art scientific speakers who lead the field as we make a transition to personalized transplant care.

4:00 PM

Precision Medicine: Applying Circulating Cell-Free DNA to Monitor Transplant Health Outcomes

Hannah Valantine, MD, National Institutes of Health, Bethesda, MD, USA

**4:15 PM** _Q &A_

4:20 PM

How to Use the Virome to Monitor Post-Transplant Immune Status

Iwijn De Vlaminck, PhD, Cornell University, Ithaca, NY, USA

**4:35 PM** _Q &A_

4:40 PM

Tissue and Circulating Long-Noncoding RNA and MicroRNA in Thoracic Transplantation

Howard J Eisen, MD, Drexel University College of Medicine, Philadelphia, PA, USA

**4:55 PM** _Q &A_

5:00 PM

Transcriptomic Analysis of Endomyocardial Biopsies for Precision Diagnosis

Jean-Paul Duong Van Huyen, MD, Hospital Necker, Paris, France

**5:15 PM** _Q &A_

5:20 PM

Next Generation Sequencing and Signatures: Applications in Transplant Diagnostics

Bruce McManus, MD, PhD, St. Paul's Hospital, Vancouver, BC, Canada

**5:35 PM** _Q &A_

5:40 PM

The Future of Precision Medicine: Genome Editing Using CRISPR/Cas9 Technology

Christof Fellmann, PhD, University of California, Berkeley, CA, USA

**5:55 PM** _Q &A_

4:00 PM - 6:00 PM

## SYMPOSIUM 23: Taming of the Shrew: Mycobacterium Abscessus in Lung Transplantation

Location:

Coronado A-C

Target Audience:

ID, ALL

**Chairs:**

Jens Gottlieb, MD, and Me-Linh Luong, MD

**Session Summary:** Mycobacterium abscessus is increasingly isolated pre- and post-lung transplant (LT). It causes a wide spectrum of infection including disseminated post-LT. Pre-LT isolation is a risk for post-LT infection and patient-to-patient transmission may occur. It is resistant to many antibiotics. Prolonged combination therapy is required and side-effects are frequent. Thus, many centers consider M. abscessus a contra-indication to LT. Good outcomes appear linked to aggressive peri-operative management. A 10-minute panel discussion with all speakers will conclude this session.

4:00 PM

Epidemiology and Modes of Transmission

Cameron Wolfe, MD, Duke University, Durham, NC, USA

**4:15 PM** _Q &A_

4:20 PM

Clinical Manifestations, Diagnosis and Antimicrobial Susceptibility

Orla Morrissey, MD, The Alfred Hospital, Melbourne, Australia

**4:35 PM** _Q &A_

4:40 PM

Management of M. Abscessus in the Lung Transplant Candidate: Preparation for Transplantation

Fernanda Silveira, MD, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

**4:55 PM** _Q &A_

5:00 PM

Antimicrobial Therapy of M. Abscessus: Current and Novel Agents

Patricia Ging, PharmD, Mater Misericordiae University Hospital, Dublin, Ireland

**5:15 PM** _Q &A_

5:20 PM

DEBATE (PRO): Patients with M. Abscessus Can Be Safely Transplanted

Gregory I Snell, FRACP, MBB, Alfred Hospital, Melbourne, Australia

5:35 PM

DEBATE (CON): Patients with M. Abscessus Can Be Safely Transplanted

Paul Corris, MB FRCP, Freeman Hospital, Newcastle upon Tyne, United Kingdom

**5:50 PM** _Panel Discussion_

6:15 PM - 7:15 PM

## MINI ORAL SESSION 7: Factors that Drive Success in MCS

Location:

Grand Hall A

Target Audience:

MCS, EEP, HF, NHSAH

**Chairs:**

Andrew J Boyle, MD, and Maryse Palardy, MD

**6:15 PM** **191)** Natural History of Mitral Regurgitation After Left Ventricular Device Implantation: Should We Intervene on the Mitral Valve?; __ M. Bishawi, J. Chien, L. McGugan, N. Hashmi, A. Nicoara, K. Cox, M. A. Daneshmand, J. Schroder, C. Patel, C. Milano. _Duke University, Durham, NC_

**6:20 PM** ( **192)** A Survey of Non-Heart Failure Cardiologists' Perception and Understanding of Left Ventricular Assist Device Therapy and Outcomes; __ A. Bitar1, K. Aaronson1, F. Pagani1, P. Shah2, R. Singh2, T. Dardas3, N. Mokadam3, J. Stulak4, S. Dunlay4, C. Salerno5, J. Cowger5. 1 _Univeristy of Michigan Health System, Ann Arbor, MI,_ 2 _Inova Heart & Vascular Institute, Falls Church, VA, _3 _University of Washington, Seattle, WA,_ 4 _Mayo Clinic, Rochester, MN,_ 5 _St Vincent Heart Center of Indiana, Indianapolis, IN_

**6:25 PM** ( **193)** Impact of Center Volume on Bridging to Transplantation with Contemporary Left Ventricular Assist Devices; __ L. K. Truby, R. Givens, A. R. Garan, R. A. Blum, A. Clemons, R. Te-Frey, M. Yuzefpolskaya, F. Latif, S. Restaino, H. Takayama, K. Takeda, D. M. Mancini, M. Farr, Y. Naka, P. C. Colombo, V. K. Topkara. _Columbia University College of Physicians and Surgeons, New York, NY_

**6:30 PM** ( **194)** Effect of the Lavare Cycle on Pump Function, Aortic Valve Opening, Autonomic Function and Activity Outcomes in Continuous Flow LVAD Patients; __ R. Clifford1, Y. D. Kim1, D. Robson1, C. Gross2, F. Moscato2, H. Schima2, P. S. Macdonald1, P. Jansz1, C. S. Hayward1. 1 _Heart Failure and Transplant Unit, St Vincent's Hospital, Sydney, Australia,_ 2 _Medical University of Vienna, Vienna, Austria_

**6:35 PM** ( **195)** Impact of Evaluation of Left Ventricular Apical Core Pathology Obtained at Time of LVAD Implantation; __ J. N. Schultz1, R. John2, C. M. Martin3, M. Pritzker3, E. Missov3, T. Thenappan3, R. Cogswell3. 1 _Department of Medicine, University of Minnesota, Minneapolis, MN,_ 2 _Department of Surgery, Division of Cardiovascular and Thoracic Surgery, University of Minnesota, Minneapolis, MN,_ 3 _Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN_

**6:40 PM** ( **196)** Previous Cardiac Operations Do Not Significantly Influence Outcome After Minimally Invasive HVAD Implantation; __ D. Böthig, C. Feldmann, J. S. Hanke, S. V. Rojas, E. Deniz, G. Dogan, A. Haverich, J. D. Schmitto. _Hannover Medical School, Hannover, Germany_

**6:45 PM** ( **197)** Impact of Body Mass Index on Left Ventricular Assist Device Support; __ J. S. Hanke, S. V. Rojas, M. Avsar, A. Uribarri, G. Dogan, E. Deniz, M. Ricklefs, C. Bara, A. Haverich, J. D. Schmitto. _Department of Cardiothoracic-, Transplantation- and Vascular Surgery, Hannover Medical School, Hannover, Germany_

**6:50 PM** ( **198)** Circadian Variation of Blood Pressure and Hemodynamics in Outpatients with Heart Mate II; __ F. Castagna1, A. Pinsino1, E. J. Stöhr1, B. McDonnell2, M. Yuzefpolskaya1, M. Flannery1, D. L. Brunjes1, N. Akter1, R. T. Te-Frey1, M. F. Pineda1, E. Royzman1, V. K. Topkara1, A. R. Garan1, H. Takayama1, K. Takeda1, Y. Naka1, J. Cockcroft2, P. C. Colombo1. 1 _New York Presbyterian Hospital - Columbia University Medical Center, New York, NY,_ 2 _Cardiff Metropolitan University, Cardiff, United Kingdom_

**6:55 PM** ( **199)** Resting Oxygen Consumption Index Is Reduced in LVAD Patients Compared to Controls and Published Estimations of Oxygen Consumption; __ T. Cascino, G. Grafton, T. M. Koelling. _University of Michigan, Ann Arbor, MI_

**7:00 PM** ( **200)** Postoperative Vasoplegia Is Strongly Associated with Short and Long Term Outcomes in Patients Receiving Left Ventricular Assist Device (LVAD) Therapy; __ B. Lima1, S. A. Hall2, G. V. Gonzalez-Stawinski1, J. Collier1, K. Tecson2, P. Kale2, S. Still1, A. Sheikh1, R. Baxter1, S. M. Joseph2. 1 _Cardiac Surgery, Baylor University Medical Center, Dallas, TX,_ 2 _Center for Advanced Heart and Lung Disease, Baylor University Medical Center, Dallas, TX_

**7:05 PM** ( **201)** Obesity Increases Risk of Thromboembolic Event After LVAD Implant? An Analysis by Devices; __ H. TOEG1, J. Stulack2, S. Dunlay2, C. Salerno3, J. Cowger3, P. Shah4, R. Singh4, T. Dardas5, K. Aaronson6, F. Pagani6, S. Maltais7. 1 _University of Ottawa Heart Insitiute, Ottawa, ON, Canada,_ 2 _Mayo Clinic, Rochester, MN,_ 3 _St Vincent Heart Center of Indiana, Indianapolis, IN,_ 4 _Inova Heart and Vascular Institute, Falls Church, VA,_ 5 _University of Washington, Seattle, WA,_ 6 _University of Michigan Medical Center, Ann Arbor, MI,_ 7 _Cardiac Surgery, Mayo Clinic, Rochester, MN_

**7:10 PM** ( **202)** Left Ventricular Assist Device Implantation in Marijuana Users; __ P. S. Joy1, G. Kumar2, J. K. Bhama1, L. M. Cadaret1. 1 _University of Iowa, Iowa City, IA,_ 2 _Northeast Georgia Health System, Gainesville, GA_

6:15 PM - 7:15 PM

## MINI ORAL SESSION 8: Infections, Induction and IVIG

Location:

Grand Hall B

Target Audience:

HTX, EEP, ID, MCS

**Chairs:**

Javier Segovia, MD, PhD, and Valentina Stosor, MD

**6:15 PM** ( **203)** Treatment with IV Antibiotics Immediately Pre-Transplant Is Associated with Increased Mortality in Heart Transplant Recipients; __ D. Vucicevic1, L. Honoris1, M. Moore1, L. Sweet1, A. Salimbangon1, A. Chang1, E. Moreno1, K. Pandya2, A. Iyengar1, S. Shah1, B. Kubak3, A. Ardehali4, M. Deng1, E. DePasquale1. 1 _Department of Cardiology, UCLA, Los Angeles, CA,_ 2 _Department of Cardiology, UC Davis, Davis, CA,_ 3 _Department of Infectious Diseases, UCLA, Los Angeles, CA,_ 4 _Department of Cardiothoracic Surgery, UCLA, Los Angeles, CA_

**6:20 PM** ( **204)** More Inactive Time on Heart Transplant List Results in Increased Post Transplant Mortality; __ D. Vucicevic1, L. Honoris1, A. Salimbangon1, A. Chang1, E. Moreno1, K. Pandya2, A. Iyengar1, S. Shah1, M. Moore1, L. Sweet1, M. Deng1, A. Ardehali3, E. DePasquale1. 1 _Department of Cardiology, UCLA, Los Angeles, CA,_ 2 _Department of Cardiology, UC Davis, Davis, CA,_ 3 _Department of Cardiothoracic Surgery, UCLA, Los Angeles, CA_

**6:25 PM** ( **205)** Sternal Wound Infection Post Orthotropic Heart Transplantation; __ H. Fernando, A. Leet. _Cardiology, Alfred Hospital, Prahran, Australia_

**6:30 PM** ( **206)** Wound Healing in Patients on Sirolimus After Heart Transplant; __ A. Putschoegl, S. Kushwaha, C. Arendt, B. Edwards, R. Daly, S. Dahl, J. Johnson. _Mayo Clinic, Rochester, MN_

**6:35 PM** ( **207)** Potential Intravenous Immunoglobulin Mediated Protection Against Severe Infections in a Randomized Clinical Trial in Solid Organ Transplantation; __ E. Sarmiento1, I. Ezzahouri1, J. Montanchez1, L. Calahorra1, S. Garcia-Jimenez1, I. Sousa-Casasnovas2, E. Zatarain2, P. Navas2, M. Rodriguez-Ferrero3, M. Salcedo4, M. Valerio5, J. Navarro1, E. Bouza5, J. Carbone1. 1 _Clinical Immunology, Hospital General Universitario Gregorio Marañon, Madrid, Spain,_ 2 _Cardiology, Hospital General Universitario Gregorio Marañon, Madrid, Spain,_ 3 _Nephrology, Hospital General Universitario Gregorio Marañon, Madrid, Spain,_ 4 _Hepatology, Hospital General Universitario Gregorio Marañon, Madrid, Spain,_ 5 _Microbiology, Hospital General Universitario Gregorio Marañon, Madrid, Spain_

**6:40 PM** ( **208)** Rituximab Induction and Risk of Cardiac Allograft Vasculopathy, Rejection and Death; __ A. Vidic1, R. Starling2, L. B. Edwards3, A. E. Toll3, P. Heeger4, L. H. Lund5, S. G. Drakos1, A. G. Kfoury6, M. H. Sayegh7, A. K. Chandraker7, J. Stehlik1. 1 _University of Utah School of Medicine, Salt Lake City, UT,_ 2 _Cleveland Clinic Foundation, Cleveland, OH,_ 3 _United Network for Organ Sharing, Richmond, VA,_ 4 _Icahn School of Medicine at Mount Sinai, New York, NY,_ 5 _Karolinska University Hospital, Stockholm, Sweden,_ 6 _Intermountain Medical Center, Salt Lake City, UT,_ 7 _Brigham and Women's Hospital, Harvard Medical School, Boston, MA_

**6:45 PM** ( **209)** Induction with Basilixumab or Thymoglobulin for Adult Heart Transplantation Transplantation; __ S. G. Al-Kindi, B. Dhakal, C. Elamm, B. Sareyyupoglu, G. H. Oliveira, M. Ginwalla. _University Hospitals Cleveland Medical Center, Cleveland, OH_

**6:50 PM** ( **210)** First Outbreak of Pneumocystis jirovecii Pneumonia in Heart Transplantation Recipients; __ E. Ammirati1, G. Veronese1, M. C. Moioli2, R. Baldan3, C. Orcese2, G. De Rezende4, S. Veronese4, E. Perna1, G. Masciocco1, G. Travi2, M. Puoti2, M. G. Mondino5, M. Cipriani1, D. M. Cirillo3, M. Frigerio1. 1 _De Gasperis CardioCenter, Niguarda Hospital, Milan, Italy,_ 2 _Infectious Diseases, Niguarda Hospital, Milan, Italy,_ 3 _Emerging Bacterial Pathogens Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy,_ 4 _Pathology, Niguarda Hospital, Milan, Italy,_ 5 _Cardiothoracic Anesthesia and Intensive Care, Niguarda Hospital, Milan, Italy_

**6:55 PM** ( **211)** Reactivation of Chagas Disease After Cardiac Transplantation; __ L. E. Schtruk1, A. F. Sales1, J. M. Sampaio1, A. K. Sà2, T. F. Guimarâes1, L. Neres2, A. S. Colafranceschi1. 1 _Insuficiência Cardíaca e Transplante, Instituto Nacional de Cardiologia, Rio de Janeiro, Brazil,_ 2 _Insuficiência Cardíaca, Hospital Pro-Cardiaco, Rio de Janeiro, Brazil_

**7:00 PM** ( **212)** The Prevalence of Hepatitis E Virus Serum Antibodies and RNA in Heart Transplant Recipients; __ K. Okamura1, K. Nawata1, M. Kimura1, O. Kinoshita1, A. Masuzawa1, H. Yamauchi1, Y. Hirata1, Y. Owada2, Y. Oshiro2, H. Okamoto3, N. Ohkohchi2, M. Ono1. 1 _Cardiac Surgery, The University of Tokyo Hospital, Bunkyo-ku Tokyo, Japan,_ 2 _Surgery, University of Tsukuba, Tsukuba Ibaraki, Japan,_ 3 _Infection and Immunity, Jichi Medical University School of Medicine, Shimotsuke Tochigi, Japan_

**7:05 PM** ( **213)** Impact of Cytomegalovirus Infection on Long-Term Heart Transplant Outcome; __ E. Mendez- Eirin, E. Barge-Caballero, M. Paniagua-Martin, D. Couto-Mallon, G. Barge-Caballero, P. Blanco-Canosa, Z. Grille-Cancela, J. Vazquez- Rodriguez, M. Crespo-Leiro. _Cardiology, Complejo Hospitalario Universitario A Coruña, A Coruña, Spain_

**7:10 PM** ( **214)** Coccidiomycosis - Screening and Prophylaxis for Thoracic Transplant Recipients in Endemic Areas; __ A. Colon, S. Pophal, S. Zangwill. _Pediatric Cardiac Transplant, Phoenix Children's Hospital, Phoenix, AZ_

6:15 PM - 7:15 PM

## MINI ORAL SESSION 9: Novel Strategies and Mechanisms in Lung Preservation, Heart Failure and Assist Devices

Location:

Grand Hall C

Target Audience:

BSTR, HTX, ID, LTX, MCS, PEDS, PHARM

**Chairs:**

Marcelo Cypel, MD, and Desiree Robson, RN BSc (Hons)

**6:15 PM** ( **215)** Microvasculature Analysis Using Micro CTA Techniques for Lungs After Different Preservation Process; __ S. Tane, K. Noda, A. J. Hayanga, J. D'Cunha, J. D. Luketich, N. Shigemura. _Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA_

**6:20 PM** ( **216)** Thermographic Evaluation During Ex Vivo Lung Perfusion for Detecting Regional Graft Damage; __ H. Motoyama, T. F. Chen-Yoshikawa, K. Hijiya, S. Tanaka, E. Miyamoto, M. Takahashi, K. Ohata, A. Aoyama, H. Date. _Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan_

**6:25 PM** ( **217)** Surfactant Metabolism During Normothermic Ex Vivo Lung Perfusion; __ L. Thakuria1, R. Romano1, V. Goss2, G. Koster2, P. Townsend2, A. Popov1, F. de Robertis1, T. Pitt1, M. Carby1, A. Simon1, N. Marczin1, M. Griffiths3, A. Postle2, A. Reed1. 1 _Dept of Transplantation, Harefield Hospital, Harefield, United Kingdom,_ 2 _University of Southampton, Southampton, United Kingdom,_ 3 _National Heart Lung Institute, Imperial College London, Harefield, United Kingdom_

**6:30 PM** ( **218)** Sphingosine-1-Phosphate Attenuates Lung Injury in Murine Model of Ex Vivo Lung Perfusion; __ J. H. Mehaffey1, E. J. Charles1, R. B. Hawkins1, S. A. Schubert1, Y. Kharel2, C. G. Tribble1, V. E. Laubach1, K. Lynch2, A. Sharma1, I. L. Kron1. 1 _Surgery, University of Virginia, Charlottesville, VA,_ 2 _Pharmacology, University of Virginia, Charlottesville, VA_

**6:35 PM** ( **219)** Anti-Inflammatory Effect of Mesenchymal Stem Cells Facilitates Lung Preservation; __ N. A. Pacienza1, D. Santa-Cruz1, M. Marcos2, O. Robledo2, G. Lemus2, A. Bertolotti3, G. Yannarelli1. 1 _Laboratorio de Regulación Génica y Células Madre, IMETTYB, Universidad Favaloro-CONICET, Ciudad Autonoma de Buenos Aires, Argentina,_ 2 _Departamento de Cirugía, Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Argentina,_ 3 _Instituto de Cardiología y Cirugía Cardiovascular, Hospital Universitario Fundación Favaloro, Ciudad Autonoma de Buenos Aires, Argentina_

**6:40 PM** ( **220)** Pirfenidone Alleviates Lung Ischemia-Reperfusion Injury in a Rat Model; __ M. Saito, T. Chen-Yoshikawa, K. Ohata, A. Takahagi, R. Okabe, F. Gochi, H. Yamagishi, M. Hamaji, H. Motoyama, K. Hijiya, A. Aoyama, H. Date. _Kyoto University, Kyoto, Japan_

**6:45 PM** ( **221)** Implantation of Spontaneously Beating Human iPS Cell-Derived Engineered Heart Tissue Does Not Provoke Ventricular Arrhythmias in a Guinea Pig Infarction Model; __ S. Pecha1, K. Breckwoldt2, M. Roehl3, A. Hansen3, A. Schwoerer4, H. Ehmke4, H. Reichenspurner1, T. Eschenhagen3. 1 _Cardiovascular Surgery, Univ Hospital Hamburg, Hamburg, Germany,_ 2 _Experimental Pharmacology and Toxicology, Univeristy Hospital Hamburg Eppendorf, Hamburg, Germany,_ 3 _Experimental Pharmacology and Toxicology, University Hospital Hamburg Eppendorf, Hamburg, Germany,_ 4 _Physiology, University Hospital Hamburg Eppendorf, Hamburg, Germany_

**6:50 PM** ( **222)** Mesenchymal to Endothelial Transition (MET) Occurs Secondary to Cardiac Unloading Through LVAD Support; __ A. S. Cruz-Solbes, C. Uribe, K. Youker, J. Amione-Guerra, B. Hanawi, J. D. Estep, B. H. Trachtenberg, A. Guha, G. Torre-Amione, E. E. Suarez, A. Bhimaraj. _Methodist DeBakey Heart Center, Houston Methodist Hospital, Houston, TX_

**6:55 PM** ( **223)** An Integrated Analysis of Metabolomics After Left Ventricular Assist Device Implantation; __ B. Fine1, A. Marx1, V. Topkara1, E. A. Gomez2, G. Vunjak-Novakovic3, P. Colombo1. 1 _Department of Medicine, Columbia University, New York, NY,_ 2 _Department of Neurology, Columbia University, New York, NY,_ 3 _Department of Biomedical Engineering, Columbia University, New York, NY_

**7:00 PM** ( **224)** Concomitant Proteomic and Metabolomic Changes upon LVAD Therapy of Ischemic Cardiomyopathy; __ J. H. Shahinian1, B. Mayer2, S. Tholen3, M. Schlimpert4, B. Kammerer5, M. Biniossek2, U. Heizmann6, F. Rueter1, M. Grapow1, O. Reuthebuch1, F. Eckstein1, F. Beyersdorf6, M. Siepe6, O. Schilling2. 1 _Cardiac Surgery, University Hospital Basel, Basel, Switzerland,_ 2 _IMMZ, University of Freiburg, Freiburg, Germany,_ 3 _IMMZ, Freiburg, Germany,_ 4 _Biology, University of Freiburg, Freiburg, Germany,_ 5 _ZBSA, University of Freiburg, Freiburg, Germany,_ 6 _Cardiac Surgery, Heart Centre Freiburg University, Freiburg, Germany_

**7:05 PM** ( **225)** Neopterin Elevation and Survival Following Left Ventricular Assist Device Implantation; __ M. M. Lander1, M. Mercurio2, K. Hanley-Yanez2, M. S. Sharbaugh1, A. D. Althouse1, M. A. Simon1, J. J. Teuteberg1, L. Lagazzi1, C. M. Sciortino1, C. McTiernan1, R. Kormos1, D. M. McNamara1. 1 _Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA,_ 2 _University of Pittsburgh Medical Center, Pittsburgh, PA_

**7:10 PM** ( **226)** Reduced PF4 and C6orf25 Gene Copies Prior to LVAD in Patients with Thromboembolic Events; __ G. H. Kim1, G. Sayer1, D. Rodgers1, R. Woodward2, P. Arnold2, N. Sarswat1, J. Grinstein1, S. Kalantari1, S. Adatya1, J. Yee2, T. Ota1, V. Jeevanandam1, N. Uriel1. 1 _University of Chicago, Chicago, IL,_ 2 _CareDx, Inc, Brisbane, CA_

6:15 PM - 7:15 PM

## MINI ORAL SESSION 10: Challenges in Lung Transplantation

Location:

Grand Hall D

Target Audience:

LTX, EEP, ID, NHSAH, PATH, PHARM

**Chairs:**

Erik Am Verschuuren, MD, PhD, and Barbara C Cahill, MD

**6:15 PM** ( **227)** Improved Survival After Lung Transplantation for Adults Requiring Pre-Operative Invasive Mechanical Ventilation: A National Cohort Study; __ B. C. Hamilton1, G. R. Dincheva2, J. A. Golden3, S. R. Hays3, L. E. Leard3, R. Shah3, M. E. Kleinhenz3, T. Deuse2, B. Trinh2, M. Brzenzinski4, M. A. Matthay5, J. P. Singer3, J. Kukreja2. 1 _Department of Surgery, UCSF, San Francisco, CA,_ 2 _Department of Surgery, Division of Cardiothoracic Surgery, UCSF, San Francisco, CA,_ 3 _Department of Medicine, Pulmonary and Critical Care, UCSF, San Francisco, CA,_ 4 _Department of Anesthesia, UCSF, San Francisco, CA,_ 5 _Department of Medicine and Anesthesia, Cardiovascular Research Institute, UCSF, San Francisco, CA_

**6:20 PM** ( **228)** Simultaneous or Sequential Lung-Kidney Transplantation Confer Superior Survival in Renal-Failure Patients Undergoing Lung Transplantation: A National Analysis; __ B. A. Yerokun1, M. S. Mulvihill1, A. A. Osho2, M. G. Hartwig1. 1 _Duke University Medical Center, Durahm, NC,_ 2 _Massachusetts General Hospital, Boston, MA_

**6:25 PM** ( **229)** De Novo Solid Organ Malignancies After Lung Transplantation: A 25-Year Single Center Experience; __ R. Waseda1, M. Hoda2, A. Benazzo2, P. Jaksch2, T. Klikovits2, G. Lang2, S. Taghavi2, W. Klepetko2. 1 _Fukuoka University, Fukuoka, Japan,_ 2 _Medical University of Vienna, Vienna, Austria_

**6:30 PM** ( **230)** Post-Transplant Lymphoproliferative Disorder After Lung Transplantation: 10-Year Experience at Duke University; __ L. Zaffiri1, C. Frankel1, E. N. Pavlisko2, S. M. Palmer1, L. D. Snyder1. 1 _Pulmonary and Critical Care, Duke University, Durham, NC,_ 2 _Pathology, Duke University, Durham, NC_

**6:35 PM** ( **231)** NonTuberculous Mycobacteria Infection and Lung Transplantation in Cystic Fibrosis: A Worldwide Survey of Clinical Practice; __ M. Brodlie1, A. Tissot2, M. F. Thomas1, P. A. Corris3. 1 _Paediatric Respiratory Medicine, Freeman Hospital/Great North Children's Hospital/Newcastle University, Newcastle upon Tyne, United Kingdom,_ 2 _Respiratory Medicine, Centre Hospitalier Universitaire de Nantes, Nantes, France,_ 3 _Respiratory Medicine, Freeman Hospital/Newcastle University, Newcastle upon Tyne, United Kingdom_

**6:40 PM** ( **232)** Preoperative Functional Independence and Employment Status Are Associated with Improved Long Term Survival After Lung Transplantation; __ A. A. Osho1, N. Lamba2, S. Hirji3, M. Mulvihill4, B. Yerokun4, M. Bishawi4, P. Spencer1, M. Villavicencio-Theoduloz1, M. Hartwig4. 1 _Surgery, Massachusetts General Hospital, Boston, MA,_ 2 _School of Medicine, Harvard University, Boston, MA,_ 3 _Surgery, Brigham and Women's Hospital, Boston, MA,_ 4 _Surgery, Duke University Hospital, Durham, NC_

**6:45 PM** ( **233)** Perceived Cognitive Difficulties and Quality of Life following Lung Transplantation; __ P. J. Smith, J. A. Blumenthal, L. D. Snyder, S. Rivelli, S. M. Palmer. _Duke University Medical Center, Durham, NC_

**6:50 PM** ( **234)** Towards Accurate Death Classification Following Lung Transplantation: The Alfred Cohort; __ K. Levin, G. Snell, M. Paraskeva. _Department of General Respiratory and Lung Transplantation, The Alfred Hospital, Melbourne, Australia_

**6:55 PM** ( **235)** Training Tomorrows Lung Transplant Surgeons - Is It Safe?; __ A. M. Altahir, K. Booth, L. E. Jones, S. C. Clark. _Cardiothoracic Surgery, Freeman Hospital (Newcastle Upon Tyne NHS Foundation Trust), Newcastle Upon Tyne, United Kingdom_

**7:00 PM** ( **236)** Cytokine Profiles of Aspergillus Isolation in Lung Transplant Recipients (LTR); __ O. Morrissey1, G. Westall2, R. Ffrench3, T. Edgell4, Y. Cristiano2, T. Phan5, B. Levvey2, G. Snell2, H. de Silva3. 1 _Infectious Diseases, Alfred Health, Melbourne, Australia,_ 2 _Respiratory Medicine, Alfred Health, Melbourne, Australia,_ 3 _Burnet Institute, Melbourne, Australia,_ 4 _Hudson Institute, Melbourne, Australia,_ 5 _Immunology and Pathology, Monash University, Melbourne, Australia_

**7:05 PM** ( **237)** A.fumigatus CYP51A Mutations in Lung Transplant Recipients; __ F. Cheema1, L. McTaggart2, L. G. Singer3, D. Kumar1, A. Humar1, C. Rotstein1, S. Keshavjee3, J. Kus2, T. Mazzulli4, S. Husain1. 1 _Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada,_ 2 _Public Health Ontario, Toronto, ON, Canada,_ 3 _Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada,_ 4 _Mount Sinai Hospital, Toronto, ON, Canada_

**7:10 PM** ( **238)** Ribavirin Efficacy in Upper and Lower Respiratory Tract Paramyxovirus Infection and Lower Respiratory Tract Paramyxovirus Infection; __ A. E. Zwart de1, A. Riezebos-Brilman2, J. C. Alffenaar3, W. Bij van der1, M. E. Erasmus4, E. A. Verschuuren1. 1 _Dept of Pulmonary Disease and Tuberculosis, Univ Med Centre Groningen, University of Groningen, Groningen, Netherlands,_ 2 _Dept of Medical Microbiology, Univ Med Centre Utrecht, Utrecht, Netherlands,_ 3 _Dept of Clinical Pharmacy and Farmacology, Univ Med Centre Groningen, University of Groningen, Groningen, Netherlands,_ 4 _Dept of Cardiothoracic Surgery, Univ Med Centre Groningen, University of Groningen, Groningen, Netherlands_

6:15 PM - 7:15 PM

## MINI ORAL SESSION 11: Outcomes in MCS

Location:

Seaport F-H

Target Audience:

MCS, HF, HTX

**Chairs:**

Paul J Mohacsi, MD, and Daniel J Goldstein, MD

**6:15 PM** ( **239)** Kidney Function After Left Ventricular Assist Device Placement; __ M. Gallo, J. R. Trivedi, W. M. Whited, M. S. Slaughter. _Department of Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, KY_

**6:20 PM** ( **240)** Acute Kidney Injury Is Highly Frequent Early After LVAD Implantation, with High Morbidity and Mortality Rates: A Multi-Centre Study; __ R. Muslem1, K. Caliskan1, S. Akin1, D. A. Hesselink2, G. J. Whitman3, R. J. Tedford4, A. J. Bogers5, O. C. Manintveld1, S. D. Russell4. 1 _Cardiology, Erasmus MC, Rotterdam, Netherlands,_ 2 _Nephrology, Erasmus MC, Rotterdam, Netherlands,_ 3 _Cardiothoracic Surgery, Johns Hopkins School of Medicine, Baltimore, MD,_ 4 _Cardiology, Johns Hopkins School of Medicine, Baltimore, MD,_ 5 _Cardiothoracic Surgery, Erasmus MC, Rotterdam, Netherlands_

**6:25 PM** ( **241)** Renal Recovery After Replacement Therapy During CF LVAD Support; __ M. Cruz, O. Saeed, S. Rangasamy, I. Katsa, J. Fertel, I. Selevany, S. R. Patel, D. B. Sims, J. Shin, D. J. Goldstein, U. P. Jorde. _Montefiore Medical Center, Bronx, NY_

**6:30 PM** ( **242)** Characteristics and Outcomes of LVAD Patients Who Undergo Pump Exchange: Axial Flow vs. Centrifugal Flow Therapy; __ F. H. Sheikh1, S. F. Mohammed1, D. T. Majure2, S. Ahmed1, M. E. Rodrigo1, M. Hofmeyer1, E. J. Molina1, S. W. Boyce1, S. S. Najjar1. 1 _MedStar Heart and Vascular Institute, MedStar Washington Hospital Center, Washington, DC,_ 2 _Northwell Health, New York, NY_

**(243)** PROMOTED TO ORAL

**6:35 PM** **(1101)** Utilisation of Hospital in the Home (HITH) by Heart and Lung Transplant Units at a Tertiary Transplant Hospital - The Alfred Health HITH Experience; __ A. Fuller1, D. Loader2, O. Strubel2, S. Lang2, D. Ferraro2, C. James2, B. Wallis2, P. Bergin3, G. Snell4. 1 _Infectious Diseases, Alfred Hospital, Melbourne, Australia,_ 2 _HITH, Alfred Hospital, Melbourne, Australia,_ 3 _Heart Transplantation, Alfred Hospital, Melbourne, Australia,_ 4 _Lung Transplantation, Alfred Hospital, Melbourne, Australia_

**6:40 PM** ( **244)** Pulmonary Artery Pulsatility Index Predicts RV Failure, Duration of Inotropes and Death After LVAD Implantation in a Large, High Acuity Cohort; __ J. D. Moreno, L. Adamo, D. S. Raymer, C. T. Sparrow, B. R. Pierce, S. J. LaRue. _Medicine, Washington University in St. Louis, St. Louis, MO_

**6:45 PM** ( **245)** Recurrent Falls in Patients with CF-LVAD's Are Associated with Major Morbidity and Mortality; __ J. K. Wong1, A. Forrest1, S. Sherazi2, L. Chen2, J. Alexis2, S. M. Friedman3, J. M. Lehoux1, H. T. Massey1, S. M. Prasad1, P. A. Knight1. 1 _Division of Cardiac Surgery, University of Rochester Medical Center, Rochester, NY,_ 2 _Division of Cardiology, University of Rochester Medical Center, Rochester, NY,_ 3 _Department of Medicine, University of Rochester Medical Center, Rochester, NY_

**6:50 PM** ( **246)** Outcomes in Patients Bridged to Long-Term Continuous Flow Left Ventricular Assist Devices Using Short-Term Mechanical Circulatory Support; __ C. Kurihara, M. Kawabori, T. Sugiura, W. E. Cohn, A. B. Civitello, O. Fraizer, J. A. Morgan. _Baylor College of Medicine, Houston, TX_

**6:55 PM** ( **247)** Right Ventricular Dysfunction Augments Risk of Adverse Outcomes in Patients with Refractory Ventricular Arrhythmias Prior to Left Ventricular Assist Device Implantation; __ R. A. Chhana1, C. T. Sparrow2, P. K. Rao2, M. E. Nassif2, E. Novak2, S. J. LaRue2, J. D. Schilling2. 1 _Department of Medicine, Washington University, St Louis, MO,_ 2 _Department of Medicine, Division of Cardiology, Washington University, St Louis, MO_

**7:00 PM** ( **248)** Similar One-Year Survival with Acute Mechanical Circulatory Support Compared to Durable Mechanical Circulatory Support Use Prior to Orthotopic Heart Transplantation: A Single Center Experience; __ D. Zisa, C. Davila, S. Patel, K. Morine, M. Esposito, M. Kiernan, D. DeNofrio, N. Kapur. _CardioVascular Center, Tufts Medical Center, Boston, MA_

**7:05 PM** ( **249)** Prolonged Support Is Associated with Increased Risk of Cellular Rejection in Patient's Bridged to Transplantation with Continuous Flow Left Ventricular Assist Devices; __ L. K. Truby, A. R. Garan, R. Givens, M. Yuzefpolskaya, A. Clemons, R. A. Blum, H. Takayama, K. Takeda, F. Latif, S. Restaino, M. Maurer, D. M. Mancini, Y. Naka, M. Farr, P. C. Colombo, V. K. Topkara. _Columbia University College of Physicians and Surgeons, New York, NY_

**7:10 PM** ( **250)** The Hemodynamic Effects of Concomitant Mitral Valve Repair and Left Ventricular Assist Device Implantation; __ J. Nnanabu1, D. Rodgers1, N. Sarswat1, J. Raikhelkar1, S. Adatya1, G. H. Kim1, D. Medvedofsky1, T. Ota1, T. Song1, D. Burkhoff2, R. M. Lang1, V. Jeevanandam1, G. Sayer1, N. Uriel1. 1 _University of Chicago, Chicago, IL,_ 2 _HeartWare International, Inc, Framingham, MA_

6:15 PM - 7:15 PM

## MINI ORAL SESSION 12: Hot Topics in Pediatric Heart Transplantation

Location:

Coronado A-C

Target Audience:

PEDS, BSTR, HTX

**Chairs:**

Steven D Zangwill, MD, and Anne I Dipchand, MD

**6:15 PM** ( **251)** Reduced Naive Regulatory T-Cells and B-10 Cells in Thymectomized Children Predispose for Allergic Disorders After Heart Transplantation; __ T. B. Kim1, N. Avdimiretz2, L. Ionescu1, I. M. Larsen1, B. Motyka1, L. J. West1, S. Urschel1. 1 _Pediatrics, University of Alberta, Edmonton, AB, Canada,_ 2 _Pediatrics, Hospital for Sick Children, Toronto, ON, Canada_

**6:20 PM** ( **252)** Age-Related Differences in the Regulatory Capacity of CD5+CD1d+ B-Cells in the Context of Heart Graft Acceptance; __ A. Hajar, L. Ionescu, Y. Ling, L. West, S. Urschel. _University of Alberta, Edmonton, AB, Canada_

**6:25 PM** ( **253)** MicroRNA-376a and -381 Correlate with Echocardiographic Indices of Graft Function in Pediatric Heart Transplant Recipients with Cardiac Allograft Vasculopathy; __ K. Watanabe, S. R. Auerbach, B. L. Stauffer, C. C. Sucharov, S. D. Miyamoto, A. Karimpour-Fard, A. Korst, P. Jone. _School of Medicine, University of Colorado Denver, Aurora, CO_

**6:30 PM** ( **254)** Refinement of Automated Whole Slide Image Analysis in Pediatric Heart Transplants; __ A. K. Bhatia1, L. Tong2, R. Hoffman3, P. Wu3, H. R. Hassanzadeh4, M. D. Wang2, S. R. Deshpande5. 1 _Pediatric Cardiology, Standford University, Stanford, CA,_ 2 _Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA,_ 3 _Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA,_ 4 _Computational Science and Engineering, Georgia Institute of Technology, Atlanta, GA,_ 5 _Pediatric Cardiology, Emory University Children's Healthcare of Atlanta, Atlanta, GA_

**6:35 PM** ( **255)** Use of Two Dimensional Speckle Tracking Echocardiography for the Detection of Acute Rejection in Pediatric Heart Transplant Recipients: A Prospective Study; __ K. Engelhardt1, M. Sorenson2, B. Das3, T. Zellers3, M. Lemler3. 1 _University of Texas Southwestern, Dallas, TX,_ 2 _Pediatrics, University of Texas Southwestern, Dallas, TX,_ 3 _Pediatric Cardiology, University of Texas Southwestern, Dallas, TX_

**6:40 PM** ( **256)** Left Atrial Function During the First Year After Pediatric Heart Transplantation; __ F. I. Lunze1, S. D. Colan1, N. Rifai2, K. Gauvreau1, M. A. Molloy1, K. Veljkovic3, P. Kavsak4, K. Adeli5, E. D. Elizabeth D. Blume1, T. P. Singh1. 1 _Cardiology, Boston Chilren's Hospital, Harvard Medical School, Boston, MA,_ 2 _Clinical Biochemistry, Boston Chilren's Hospital, Harvard Medical School, Boston, MA,_ 3 _Departments of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada,_ 4 _Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada,_ 5 _Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON_

**6:45 PM** ( **257)** Post-Transplant Outcomes of Children with Donor-Recipient Race Mismatch in the USA: An Analysis of the UNOS Database; __ A. G. Cabrera1, J. F. Price1, I. Adachi2, B. Elias2, S. W. Denfield1, W. J. Dreyer1, H. P. Tunuguntla1, N. J. Rodgers1, A. Jeewa1. 1 _Pediatrics, Baylor College of Medicine/Texas Children's Hospital, Houston, TX,_ 2 _Surgery, Baylor College of Medicine/Texas Children's Hospital, Houston, TX_

**6:50 PM** ( **258)** Japanese Registry for Pediatric Heart Transplantation: The First Report 2017; __ N. Fukushima1, M. Ono2, S. Kogaki3, Y. Sawa4. 1 _Department of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Japan,_ 2 _Department of Cardiac Surgery, University of Tokyo, Tokyo, Japan,_ 3 _Department of Pediatrics, Osaka University, Suita, Japan,_ 4 _Department of Cardiovascular Surgery, Osaka Univeristy, Suita, Japan_

**6:55 PM** ( **259)** Poor Outcomes After Heart Transplant: Being a Teenager Does Not Stop at Age 18; __ R. S. Baker, R. Rizwan, R. Bryant 3rd, C. Villa, C. Chin, J. S. Tweddell, F. Zafar, D. L. Morales. _Cardiothoracic Surgery, Cincinnati Children's Hospital, Cincinnati, OH_

**7:00 PM** ( **260)** Psychosocial Determinants of Health in Young Heart Transplant Recipients: Thinking Outside the Box; __ N. R. Dempster1, R. Gajarski2, L. Fisher2, H. Missler2, T. Cole3, D. Nandi2. 1 _Department of Psychology and Neuropsychology, Nationwide Children's Hospital, Columbus, OH,_ 2 _Department of Cardiology, Nationwide Children's Hospital, Columbus, OH,_ 3 _Department of Social Work, Nationwide Children's Hospital, Columbus, OH_

**7:05 PM** ( **261)** Recovery of Microcirculation and Tissue Oxygenation After Pediatric Heart Transplantation: New Insight into an Old Problem; __ D. Gupta1, D. Lopez-Colon1, B. A. Pietra1, M. S. Bleiweis1, F. J. Fricker1, R. S. Samraj2. 1 _Congenital Heart Center, Department of Pediatrics, University of Florida, Gainesville, FL,_ 2 _Pediatric Critical Care Medicine, Department of Pediatrics, University of Florida, Gainesville, FL_

**7:10 PM** ( **262)** Safety Problems Associated with Extemporaneously-Prepared Liquid Tacrolimus in US Children After Heart Transplantation; __ N. McDonald1, J. Lee1, E. Pahl2, J. Rosanno3, K. Daly4, A. J. Burnette5, C. Hartman6, H. Bastardi7, V. Peiris8, C. Almond9. 1 _Heart Transplant, Lucile Packard Childrens Hospital, Palo Alto, CA,_ 2 _Heart Transplant, Lurie Children's Hospital, Chicago, IL,_ 3 _Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA,_ 4 _Cardiology, Boston Children's Hospital, Boston, MA,_ 5 _Heart Transplant, Medical University of South Carolina, Columbia, SC,_ 6 _Heart Transplant, Children National Health System, Washington, DC,_ 7 _Heart Transplant, Boston Children's Hospital, Boston, MA,_ 8 _US Food and Drug Administration, Silver Spring, MD,_ 9 _Heart Transplant, Stanford Hospital, Palo Alto, CA_

# Friday, April 07, 2017

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 07: Getting to the Heart of Muscular Dystrophies

Location:

Grand Hall A

Target Audience:

ALL

**Chairs:**

Forum Kamdar, MD PhD, and Takeshi Nakatani, MD, PhD

**Session Summary:** Neuromuscular disorders result in significant skeletal muscle weakness and increasingly severe cardiomyopathy. The objectives of this session are to identify cardiomyopathy as a common sequela of neuromuscular disorders, review current medical therapies for treating heart failure in this unique population, and discuss the use of advanced heart failure therapies such as cardiac transplantation and LVADs for pediatric and adult patients with end-staged neuromuscular cardiomyopathy.

**7:00 AM**

Heart Failure in Muscular Dystrophies: No Longer Just a Skeletal Muscle Disorder

Daniel J Garry, MD, PhD, University of Minnesota Medical Center, Minneapolis, MN, USA

**7:10 AM** _Q &A_

**7:15 AM**

Heart Failure Medical Treatment for Muscular Dystrophy: When and How to Treat

Denis Duboc, MD, CHU Paris Centre, Hospital Cochin, Paris, France

**7:25 AM** _Q &A_

**7:30 AM**

Mechanical Circulatory Support in Muscular Dystrophy Cardiomyopathy

Antonio Amodeo, MD, Bambino Gesu Pediatric Hospital, Rome, Italy

**7:40 AM** _Q &A_

**7:45 AM**

Cardiac Transplantation in Muscular Dystrophies

Jeffrey Towbin, MD, Le Bonheur Children's Hospital, Memphis, TN, USA

**7:55 AM** _Q &A_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 08: Live Long and Prosper: Thriving After Pediatric Transplantation

Location:

Grand Hall B

Target Audience:

PEDS, EEP, HF, HTX, LTX, MCS, NHSAH, PHARM

**Chairs:**

Caron L Burch, MSN, and Estela Azeka, MD

**Session Summary:** The session will focus on the psychosocial, behavioral challenges as well as communication and developmental issues in pediatric transplant patients. Specific attention will be given to adolescence and models for transition.

7:00 AM

Neurodevelopmental Outcomes after Pediatric Cardiothoracic Transplant

Simon Urschel, MD, University of Alberta, Edmonton, AB, Canada

**7:10 AM** _Q &A_

7:15 AM

Keep Moving! Physical Exercise and Competitive Sports After Pediatric Transplantation

Kari Nytroen, PhD, Oslo University Hospital Rikshospitalet, Oslo, Norway

**7:25 AM** _Q &A_

7:30 AM

Nobody Understands Me! Communication Strategies to Reach Teenagers and Young Adults

Melissa Cousino, PhD, University of Michigan Transplant Center, Ann Arbor, MI, USA

**7:40 AM** _Q &A_

7:45 AM

Transitioning to Adult Care: Does Anything Work?

Jonathan N Johnson, MD, Mayo Clinic, Rochester, MN, USA

**7:55 AM** _Q &A_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 09: Mixed Rejection (MR) of the Cardiac Allograft: The Next Frontier

Location:

Grand Hall C

Target Audience:

PATH, BSTR, HF, HTX

**Chairs:**

Gerald J. Berry, MD, and Marny Fedrigo, MD, PhD

**Session Summary:** Cellular rejection and antibody mediated rejection are well-characterized. These two forms of rejection are most often considered separately, if not mutually exclusive. Increasingly, an overlap in features of these two rejection patterns is being noted (coined "mixed rejection"). Insights into the immune mechanisms of rejection may be gleaned from a better understanding of mixed rejection. A panel discussion with all speakers will conclude this session.

7:00 AM

T- and B-cell Immunity in Mixed Rejection: Time to Tango

Anne Halpin, MSc, University of Alberta, Edmonton, AB, Canada

7:15 AM

Is the Pathology of Mixed Rejection More Than Just ACR + AMR? See for Yourself

Dylan Miller, MD, Intermountain Central Laboratory, Salt Lake City, UT, USA

7:30 AM

Clinical Insights into the Behavior of Mixed Rejection in Heart Transplantation

A. G Kfoury, MD, FACC, Intermountain Medical Center, Murray, UT, USA

**7:45 AM** _Panel Discussion_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 10: Contrasts and Similarities in Children and Adults: IPAH, Portopulmonary Hypertension, and Perioperative Management

Location:

Grand Hall D

Target Audience:

PH, BSTR, HF, LTX, NHSAH, PEDS, PHARM

**Chairs:**

Jean-Luc Vachiery, MD, and Brian Feingold, MD

**Session Summary:** This symposium will provide attendees with details on current management of pulmonary arterial hypertension (PAH) in adults and children. Three different clinical scenarios are discussed: idiopathic PAH, portopulmonary PAH, and perioperative PAH care. A panel discussion with all speakers will conclude this session.

7:00 AM

New Treatment Paradigms in IPAH Management in Children: How do we extrapolate data from Adults?

Erika Berman Rosenzweig, MD, Columbia University, New York, NY, USA

7:15 AM

Challenges in Portopulmonary hypertension: Different in Children?

Michel De Pauw, MD, Ghent University Hospital, Ghent, Belgium

7:30 AM

Peri-operative Management of Infants, Children, and Adolescents with Pulmonary Vascular Disease: "Tried as an Adult"?

Jacqueline R. Szmuszkovicz, MD, Children's Hospital, Los Angeles, CA, USA

**7:45 AM** _Panel Discussion_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 11: There is No Such Thing as Perfect: Selecting Recipients for Lung Transplantation

Location:

Seaport F-H

Target Audience:

LTX, ID, NHSAH, PEDS

**Chairs:**

Rupal Shah, MD, and Daniel C. Chambers, MBBS, MRCP, FRACP, MD

**Session Summary:** Selection of lung transplant recipients is challenging, often due to limitations of current selection criteria. This sunrise symposium highlights cutting edge research and practical knowledge on physiologic factors, psychological features and non-standard, controversial or rare transplant indications to assist in selecting lung transplant recipients.

7:00 AM

Identifying the Right Candidate: Body Composition, Physiologic Frailty and Age

Jonathan P Singer, MD, MS, UCSF Medical Center, San Francisco, CA, USA

**7:17 AM** _Q &A_

7:20 AM

Psychological and Neurocognitive Frailty: Effect on Transplant Outcomes

James A Blumenthal, PhD, Duke University Medical Center, Durham, NC, USA

**7:37 AM** _Q &A_

7:40 AM

"Extended Criteria" Recipients: How Far Should We Go?

Jens Gottlieb, PhD, Hannover Medical School, Hannover, Germany

**7:57 AM** _Q &A_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 12: HIV and Transplantation: It Isn't Going Away...

Location:

Coronado A-C

Target Audience:

PHARM, HTX, ID, LTX, NHSAH, PEDS, PH

**Chairs:**

Patricia Uber, PharmD, and Joanna M. Schaenman, MD, PhD

**Session Summary:** This session will review end-stage heart and lung diseases associated with HIV and discuss key infectious diseases and pharmacotherapy management considerations in both the transplant and post-transplant phases of care. Lastly, HIV to HIV transplantation in the cardio-thoracic population will be discusses.

7:00 AM

The ART and Science of HIV Associated Cardiomyopathy

Marco Masetti, MD, Malpighi University Hospital, Bologna, Italy

**7:10 AM** _Q &A_

7:15 AM

HIV Associated Pulmonary Arterial Hypertension: True, True and Related

Robert Frantz, MD, Mayo Clinic, Minneapolis, MN, USA

**7:25 AM** _Q &A_

7:30 AM

HIV: the ID Perspective on the Donor and Recipient

Valentina Stosor, MD, Northwestern University, Chicago, IL, USA

**7:40 AM** _Q &A_

7:45 AM

A Delicate Balance: Management of Transplant Meds, HIV Meds, and ID Prophylaxis Meds

Christine Hui, PharmD, UCSF Medical Center, San Francisco, CA, USA

**7:55 AM** _Q &A_

8:00 AM - 9:30 AM

## ORAL SESSION 20: New and Improving? Evolving Outcomes with MCS

Location:

Seaport A-E

Target Audience:

MCS, EEP, HF, HTX, NHSAH

**Chairs:**

Claudius Mahr, DO, and Patricia P Chang, MD

**8:00 AM** ( **263)** Clinical Outcomes with Heartmate 3 as Treatment for Advanced HF: First Data from the European ELEVATE Registry; __ F. Gustafsson1, M. Morshuis2, D. Zimpfer3, J. Lavee4, T. Krabatsch5, S. Shaw6, D. Saeed7, L. Damme8, J. Garbade9. 1 _Rigshospitalet, Copenhagen, Denmark,_ 2 _HDZ NRW, Bad Oyenhausen, Germany,_ 3 _Medical University Vienna, Vienna, Austria,_ 4 _Sheba Medical Center, Ramat Aviv, Israel,_ 5 _Deutsches Herz Zentrum, Berlin, Germany,_ 6 _Wythenshawe Hospital, Manchester, United Kingdom,_ 7 _Heinrich-Heine Universität Düsseldorf, Dusseldorf, Germany,_ 8 _St Jude Medical, Zaventem, Belgium,_ 9 _Herzzentrum Leipzig GmbH, Leipzig, Germany_

**8:15 AM** ( **264)** Bridging to Transplantation with Contemporary Continuous-Flow Left Ventricular Assist Devices: A Decade Experience; __ L. K. Truby, R. Givens, A. R. Garan, M. Yuzefpolskaya, M. Flannery, H. Takayama, K. Takeda, J. Haythe, F. Latif, S. Restaino, M. Maurer, D. M. Mancini, Y. Naka, M. Farr, P. C. Colombo, V. K. Topkara. _Columbia University College of Physicians and Surgeons, New York, NY_

**8:30 AM** ( **265)** Five-Year Outcome in Patients Treated with Heart Transplantation with Advanced Age Donors versus Patients on Waiting List for Heart Transplantation Implanted with Left Ventricular Assist Device; __ E. Ammirati, M. Cipriani, E. Perna, M. Varrenti, T. Colombo, A. Garascia, A. Cannata, G. Pedrazzini, F. Milazzo, F. Oliva, M. P. Gagliardone, C. F. Russo, M. Frigerio. _De Gasperis CardioCenter, Niguarda Hospital, Milan, Italy_

**8:45 AM** ( **266)** Which INTERMACS 4-7 Patients Are at Low Risk for Mortality at One Year? Insights from the INTERMACS Database; __ J. J. Teuteberg1, A. D. Althouse1, M. Shullo1, N. Kunz1, K. Lockard1, E. Dunn1, L. Lagazzi1, C. Sciortino1, J. Cowger2, S. Joseph3, R. L. Kormos1. 1 _University of Pittsburgh, Pittsburgh, PA,_ 2 _St. Vincent, Indianapolis, IN,_ 3 _Baylor Medical Center, Houston, TX_

**9:00 AM** ( **267)** Outcomes of Jarvik 2000 LVAD as a Bridge to Heart Transplantation: Data from the Japanese Registry for Mechanically Assisted Circulatory Support (J-MACS); __ H. Kohno1, G. Matsumiya1, Y. Sawa2, M. Ono3, Y. Saiki4, A. Shiose5, K. Yamazaki6, Y. Matsui7, H. Niinami8, H. Matsuda9, S. Kitamura10, T. Nakatani11, S. Kyo12. 1 _Cardiovascular Surgery, Chiba University Graduate School of Medicine, Chiba, Japan,_ 2 _Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan,_ 3 _Cardiac Surgery, The University of Tokyo, Tokyo, Japan,_ 4 _Cardiovascular Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan,_ 5 _Cardiovascular Surgery, Kyushu University Faculty of Medical Sciences, Fukuoka, Japan,_ 6 _Cardiovascular Surgery, Tokyo Women's Medical University Hospital, Tokyo, Japan,_ 7 _Cardiovascular and Thoracic Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan,_ 8 _Cardiovascular Surgery, Saitama Medical University International Medical Center, Hidaka, Japan,_ 9 _Higashi-Takarazuka Satoh Hospital, Takarazuka, Japan,_ 10 _National Cerebral and Cardiovascular Center, Osaka, Japan,_ 11 _Maki Health Care Group, Maki Hospital, Osaka, Japan,_ 12 _Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan_

**9:15 AM** ( **268)** Effects of Hospital Characteristics on In-Hospital Mortality and Hospitalization Costs for Mechanical Circulatory Support Device (MCSD) Therapy: Results from the National (Nationwide) Inpatient Sample (NIS); __ L. Sridharan1, R. Givens1, A. R. Garan1, M. Yuzefpolskaya1, K. Takeda2, F. Latif1, S. Restaino1, J. Haythe1, M. Maurer1, D. M. Mancini3, M. Farr1, Y. Naka2, P. C. Colombo1, V. Topkara1. 1 _Cardiology, Columbia University, New York, NY,_ 2 _Cardiothoracic Surgery, Columbia University, New York, NY,_ 3 _Cardiology, Mount Sinai, New York, NY_

8:00 AM - 9:30 AM

## ORAL SESSION 21: New Fixes for an Old Problem: Preventing, Diagnosing, and Treating Pump Thrombosis

Location:

Grand Hall A

Target Audience:

MCS, HF, NHSAH, PHARM

**Chairs:**

Evgenij V Potapov, MD, PhD, and Allen Cheng, MD

**8:00 AM** ( **269)** Management and Outcomes of LVAD Thrombosis: A Systematic Review and Meta-Analysis; __ V. Tchantchaleishvili1, J. G. Luc2, K. Phan3, S. M. Dunlay4, S. Maltais1, J. M. Stulak1. 1 _Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN,_ 2 _Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada,_ 3 _Faculty of Medicine, University of Sydney, Sydney, Australia,_ 4 _Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN_

**8:15 AM** ( **270)** Novel Techniques of Sound Wave Analysis Can Detect Ventricular Assist Device Thrombosis; __ M. Bran Pouyan1, L. Blazquez Arroyo2, S. Hersek1, M. Janmohamed2, T. De Marco2, G. M. Wieselthaler3, V. N. Selby2, O. T. Inan1, L. Klein2. 1 _School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA,_ 2 _Cardiology, University of California, San Francisco, CA,_ 3 _Cardiac Surgery, University of California, San Francisco, CA_

**8:30 AM** ( **271)** Apixabanin Mechanical Circulatory Support - Evaluation in a Mock Circulatory Loop with Human Blood; __ S. Rao1, D. Connor2, N. Kerr3, J. Joseph4, P. Jansz1, C. Hayward1. 1 _Heart Transplant, St Vincent's Hospital, Darlinghurst, Australia,_ 2 _St Vincent's Centre for Applied Medical Research, Darlinghurst, Australia,_ 3 _St Vincent's Hospital, Darlinghurst, Australia,_ 4 _Heamatology, St Vincent's Hospital, Darlinghurst, Australia_

**8:45 AM** ( **272)** Left Atrial Appendage Occlusion Is Associated with Decreased Thromboembolic Events in LVAD Patients; __ A. Deshmukh, A. Bhatia, N. Sarswat, S. Adatya, G. Kim, G. Sayer, C. Ozcan, T. Ota, V. Jeevanandam, N. Uriel. _University of Chicago, Chicago, IL_

**9:00 AM** ( **273)** Trends in Serum Lactate Dehydrogenase During HeartMate II Left Ventricular Assist Device Support and Its Relation to Clinical Outcomes: Insights from the PREVENT Study; __ T. Thenappan1, J. Stulak2, R. Agarwal3, S. Maltais2, P. Shah4, P. Eckman5, S. Emani6, J. Katz7, I. Gregoric8, M. Keebler9, N. Uriel10, E. Adler11, J. Chuang12, D. Farrar12, K. Sundareswaran12, R. John1. 1 _University of Minnesota, Minneapolis, MN,_ 2 _Mayo Clinic, Rochester, MN,_ 3 _Allegheny General Hospital, Pittsburgh, PA,_ 4 _Inova Heart and Vascular Institute, Falls Church, VA,_ 5 _Minneapolis Heart Institute, Minneapolis, MN,_ 6 _Ohio State University Medical Center, Columbus, OH,_ 7 _University of North Carolina, Chapel Hill, NC,_ 8 _Memorial Hermann - Texas Medical Center, Houston, TX,_ 9 _Vanderbilt University, Nashville, TN,_ 10 _University of Chicago Medical Center, Chicago, IL,_ 11 _University of California San Diego Medical Center, La Jolla, CA,_ 12 _St. Jude Medical, Pleasanton, CA_

**9:15 AM** ( **274)** Sildenafil Reduces Risk of Ischemic Stroke and Pump Thrombosis with Ongoing Low Level Hemolysis During Heart Mate II Support; __ O. Saeed1, S. Rangasamy1, A. Luke1, S. P. Patel1, D. B. Sims1, J. Shin1, M. Reyes Gil2, M. J. Slepian3, H. H. Billett2, D. J. Goldstein4, U. P. Jorde1. 1 _Medicine (Cardiology), Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY,_ 2 _Medicine (Hematology), Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY,_ 3 _Medicine (Cardiology), University of Arizona, Tucson, AZ,_ 4 _Surgery (Cardiothoracic), Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY_

8:00 AM - 9:30 AM

## ORAL SESSION 22: Does Risk Reap Reward? Expanding the Heart Donor Pool

Location:

Grand Hall B

Target Audience:

HTX, BSTR

**Chairs:**

Mahazarin B Ginwalla, MD, and Paul Christian Schulze, MD, PhD

**8:00 AM** ( **275)** Outcomes for Donor Hearts with Low Ejection Fraction That Improve During Donor Management; __ S. Madan1, O. Saeed1, P. Vlismas1, I. Katsa2, S. R. Patel1, J. Shin1, D. Sims1, D. Goldstein3, U. P. Jorde1. 1 _Cardiology, Montefiore Medical Center/Albert Einstein College of Medicine, New York, NY,_ 2 _Medicine, Jacobi Medical Center/Albert Einstein College of Medicine, New York, NY,_ 3 _Cardiovascular and Thoracic Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, New York, NY_

**8:15 AM** ( **276)** Center for Disease Control High Risk Donor Use in Heart Transplantation: Current Trends; __ A. Iyengar1, D. Vucicevic2, E. Adams1, C. Eisenring3, L. Reardon2, M. Deng2, A. Ardehali3, E. DePasquale2. 1 _David Geffen School of Medicine, University of California - Los Angeles, Los Angeles, CA,_ 2 _Department of Cardiology, University of California - Los Angeles, Los Angeles, CA,_ 3 _Department of Cardiac Surgery, University of California - Los Angeles, Los Angeles, CA_

**8:30 AM** ( **277)** Changing Dynamics of Donor Hearts: Impact of Drug Intoxicated Organs on Survival; __ J. R. Trivedi, M. Gallo, W. M. Whited, M. S. Slaughter. _Department of Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, KY_

**8:45 AM** ( **278)** Predicted Heart Mass Is the Optimal Metric for Size Matching in Heart Transplantation; __ E. Kransdorf, M. Kittleson, J. Patel, T. Aintablian, A. Velleca, E. Stimpson, D. Geft, D. H. Chang, L. Czer, A. Trento, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**9:00 AM** ( **279)** Close to the Heart: Increasing Geographic Distance from Transplanting Center Associated with Increased Incidence of Graft Failure and Mortality Following Heart Transplant; __ T. Khuu1, B. Chen1, M. Cadeiras2. 1 _UCLA, Los Angeles, CA,_ 2 _Medicine, UCLA, Los Angeles, CA_

**9:15 AM** ( **280)** Prediction of Waitlist Mortality in Adult Heart Transplant Candidates: The Candidate Risk Score; __ C. Jasseron1, C. Legeai1, C. Jacquelinet1, P. Leprince2, C. Cantrelle1, B. Audry1, R. Porcher3, O. Bastien1, R. Dorent1. 1 _Direction Prélèvement Greffe Organes-Tissus, Agence de la Biomédecine, Saint-Denis La Plaine, France,_ 2 _Service de Chirurgie Cardio-Vasculaire, Hôpital de la Pitié Salpêtrière, Paris, France,_ 3 _Centre d'Epidémiologie Clinique, Hôpital Hôtel-Dieu, Paris, France_

8:00 AM - 9:30 AM

## ORAL SESSION 23: Choosing Right: Lung Recipient Selection and Management

Location:

Grand Hall C

Target Audience:

LTX, BSTR, EEP, NHSAH, PHARM

**Chairs:**

Roger D. Yusen, MD, MPH, and Marie M Budev, DO, MPH

**8:00 AM** ( **281)** The Lung Transplant Risk Model - A Nationally Validated Tool for Pre-Transplant Risk Assessment; __ E. Y. Chan1, D. T. Nguyen2, N. Sinha3, T. S. Kaleekal3, A. Goodarzi3, J. G. Youssef3, B. A. Bruckner4, E. E. Suarez4, S. A. Scheinin4, E. A. Graviss2, A. O. Gaber5. 1 _Division of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, Houston, TX,_ 2 _Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX,_ 3 _Division of Transplant Pulmonology, Department of Medicine, Houston Methodist Hospital, Houston, TX,_ 4 _Department of Cardiovascular Surgery, Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, TX, _5 _Department of Surgery, Houston Methodist Hospital, Houston, TX_

**8:15 AM** ( **282)** Underutilization of Lung Transplant Referral Among Patients with Newly Diagnosed Idiopathic Pulmonary Fibrosis (IPF); __ L. Paoletti1, S. Palmer2, E. Yow3, M. L. Neely3, V. Gamerman4, T. Whelan1. 1 _Medical University of South Carolina, Charleston, SC,_ 2 _Department of Medicine, Duke University Medical Center and Duke Clinical Research Institute, Durham, NC,_ 3 _Duke Clinical Research Institute, Durham, NC,_ 4 _Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT_

**8:30 AM** ( **283)** Cost and Readmission of Single and Double Lung Transplantation in the U.S. Medicare Population; __ F. McCarthy, D. Savino, D. Graves, T. Dibble, C. Brown, D. Spragan, C. Bermudez, E. Cantu, D. Nimesh. _Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA_

**8:45 AM** ( **284)** Technique and Outcomes of Less Invasive Lung Retransplantation; __ W. Sommer1, F. Ius1, C. Kuehn1, M. Avsar1, J. Salman1, T. Siemeni1, J. Gottlieb2, N. Schwerk3, A. Haverich1, I. Tudorache1, G. Warnecke1. 1 _Cardiothoracic Surgery, Hannover Medical School, Hannover, Germany,_ 2 _Respiratory Medicine, Hannover Medical School, Hannover, Germany,_ 3 _Pediatric Respiratory Medicine, Hannover Medical School, Hannover, Germany_

**9:00 AM** ( **285)** Functions of Inverted Grafts Are Satisfactory Compared with Non-Inverted Grafts in Living-Donor Lobar Lung Transplantation; __ H. Kayawake, T. F. Chen-Yoshikawa, Y. Goda, H. Oda, S. Ueda, H. Motoyama, M. Hamaji, K. Hijiya, A. Aoyama, H. Date. _Department of Thoracic Surgery, Kyoto University, Kyoto, Japan_

**9:15 AM** ( **286)** A Comparison of Propofol Based Total Intravenous Anesthesia and Sevoflurane Based Balanced Anesthesia on Renal Protection During Lung Transplantation Under Extracorporeal Membrane Oxygenation - A Prospective, Randomized Trial; __ N. Kim1, J. G. Lee2, S. Lee2, K. S. Nam2, J. W. Shu2, H. C. Paik2, Y. C. Yoo1. 1 _Anesthesiology, Yonsei University, Seoul, Korea, Republic of,_ 2 _Thoracic and Cardiovascular Surgery, Yonsei University, Seoul, Korea, Republic of_

8:00 AM - 9:30 AM

## ORAL SESSION 24: An Amalgamation of Support in Heart Failure

Location:

Grand Hall D

Target Audience:

HF, MCS, NHSAH, PHARM

**Chairs:**

Savitri Fedson, MD, and Navin K Kapur, MD

**8:00 AM** ( **287)** MitraClip Therapy for Patients with End-Stage Heart Failure: A Durable Option?; __ D. Reichart, D. Kalbacher, N. Schofer, F. Deuschl, J. Schirmer, S. Blankenberg, H. Reichenspurner, U. Schäfer, E. Lubos, L. Conradi. _University Heart Center Hamburg, Hamburg, Germany_

**8:15 AM** ( **288)** Percutaneous Axillary Balloon Pumps: Outcomes of Extended Support; __ D. A. Baran, K. Stelling, J. Pieretti, C. Gidea, S. Kapoor, M. J. Zucker, M. Cohen, T. Martin, B. Dinicola, M. Camacho. _Newark Beth Israel Medical Ctr, Newark, NJ_

**8:30 AM** ( **289)** Predictors of Hemodynamic Stabilization Following Intra-Aortic Balloon Pump Implantation for Cardiogenic Shock; __ C. Juricek1, T. Imamura2, H. Costantini1, V. Kagan1, T. Song1, D. Onsager1, T. Ota1, S. Adatya2, G. Kim2, N. Sarswat2, G. Sayer2, V. Jeevanandam1, N. Uriel2. 1 _CT Surgery, University of Chicago, Chicago, IL,_ 2 _Cardiology, University of Chicago, Chicago, IL_

**8:45 AM** ( **290)** The ASA Score - A Simple Way to Predict Outcome of Non-Transplant Eligible Patients Receiving Palliative Inotropic Therapy; __ E. Achu1, D. A. Baran1, A. Harhash2, M. J. Zucker1, J. Crincoli1, M. Rovner2, M. Mody1, Z. Port1, A. Hussein2, S. Kapoor1, J. Pieretti1, C. Gidea1, M. Goldschmidt2. 1 _Newark Beth Israel Medical Ctr, Newark, NJ,_ 2 _Morristown Medical Center, Morristown, NJ_

**9:00 AM** ( **291)** Tolerability of High Dose Continuous Outpatient Milrinone: Time to Re-Evaluate?; __ A. Harhash1, E. Achu2, M. J. Zucker2, M. Goldschmidt1, M. Rovner1, J. Crincoli2, A. Hussein1, J. Pieretti2, C. Gidea2, M. Mody2, Z. Port2, S. Kapoor2, D. A. Baran2. 1 _Morristown Medical Center, Morristown, NJ,_ 2 _Newark Beth Israel Medical Ctr, Newark, NJ_

**9:15 AM** ( **292)** Seattle Heart Failure Model Predicted One-Year Mortality of 20% or More Is Associated with a Poor Prognosis in Patients Referred for Heart Transplant Assessment; __ P. Narayan, S. Drew, A. Bin Mohd Ghazi, C. Lewis, J. Parameshwar, S. J. Pettit. _Transplant Unit, Papworth Hospital NHS Foundation Trust, Cambridge, United Kingdom_

8:00 AM - 9:30 AM

## ORAL SESSION 25: Improving Outcomes in Pediatric Lung Transplantation

Location:

Seaport F-H

Target Audience:

PEDS, ID, LTX

**Chairs:**

Carol K Conrad, MD, and Malcolm Brodlie, BSc (Hons), MB ChB, PhD, MRCPCH

**8:00 AM** ( **293)** Long-Term Outcomes After Living-Donor Lobar Lung Transplantation Using a Single Donor; __ S. Ueda, T. F. Chen-Yoshikawa, H. Motoyama, M. Hamaji, K. Hijiya, A. Aoyama, H. Date. _Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan_

**8:15 AM** ( **294)** Respiratory Viral Infections in Pediatric Lung Transplant Recipients Are Not Associated with BOS, Retransplant or Death; __ S. C. Sweet1, R. Buller1, H. Chin2, C. Conrad3, A. Faro4, S. Goldfarb5, D. Hayes6, P. Heeger7, D. Ikle2, K. Kesler2, E. Melicoff-Portillo8, T. Mohanakumar9, M. Schecter10, G. Storch1, G. Visner11, N. Williams12, L. Danziger-Isakov10. 1 _Washington University, St. Louis, MO,_ 2 _Rho, Inc., Chapel Hill, NC,_ 3 _Lucille Packard Children's Hospital, Palo Alto, CA,_ 4 _Cystic Fibrosis Foundation, Bethesda, MD,_ 5 _Children's Hospital of Philadephia, Philadephia, PA,_ 6 _Nationwide Children's Hospital, Columbus, OH,_ 7 _Mount Sinai School of Medicine, New York, NY,_ 8 _Texas Children's Hospital, Houston, TX,_ 9 _St. Joseph's Hospital & Medical Center, Phoenix, AZ, _10 _Cincinnati Children's Hosp Med Ctr, Cincinnati, OH,_ 11 _Boston Children's Hospital, Boston, MA,_ 12 _National Institutes of Health, Bethesda, MD_

**8:30 AM** ( **295)** Autotransplantation of the Left Lung for the Treatment of Recurrent Life Threatening Pulmonary Hemorrhage Related to Pulmonary Vascular Malformation: A Novel Treatment Approach & a Unique Chance to Study Ischemia/Reperfusion Injury; __ C. Falk1, I. Tudorache2, C. Mueller3, W. Sommer4, K. Daeman1, J. Keil1, C. Neudörfl1, G. Hansen3, A. Haverich4, G. Warnecke4, I. Tudorache4. 1 _Institute of Transplant Immunology, IFB-Tx, Hannover Medical School, Hannover, Germany,_ 2 _Cardiac-,Thoracic-, Trasplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany,_ 3 _Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany,_ 4 _Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany_

**8:45 AM** ( **296)** Risk and Outcomes of Pulmonary Fungal Infection in Pediatric Lung Transplant; __ E. Ammerman1, L. Danziger-Isakov1, G. A. Storch2, M. Fenchel1, C. Conrad3, D. Hayes4, A. Faro2, S. Goldfarb5, K. Kesler6, E. Melicoff-Portillo7, M. Schecter1, G. Visner8, N. Williams9, S. C. Sweet2. 1 _Children's Hosp Med Ctr, Cincinnati, OH,_ 2 _Washington University/St. Louis Children's Hospital, St. Louis, MO,_ 3 _Lucile Packard Children's Hospital at Stanford University, Palo Alto, CA,_ 4 _Nationwide Children's Hospital, Columbus, OH,_ 5 _Children's Hospital of Philadephia, Philadelphia, PA,_ 6 _Rho, Inc, Chapel Hill, NC,_ 7 _Texas Children's Hospital, Houston, TX,_ 8 _Harvard Medical School/Boston Children's Hospital, Boston, MA,_ 9 _National Institute of Allergy and Infectious Diseases, Bethesda, MD_

**9:00 AM** ( **297)** Anellovirus Can Be Used to Predict Short- and Long-Term Outcomes in Pediatric Lung Transplant Recipients; __ J. Blatter1, S. Sweet1, C. Conrad2, L. A. Danziger-Isakov3, A. Faro4, S. B. Goldfarb5, D. Hayes, Jr.6, E. Melicoff7, M. Schecter8, G. Storch1, G. A. Visner9, N. M. Williams10, D. Wang11. 1 _Department of Pediatrics, Washington University School of Medicine in St. Louis, Saint Louis, MO,_ 2 _Department of Pediatrics, Stanford University School of Medicine, Stanford, CA,_ 3 _Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH,_ 4 _Cystic Fibrosis Foundation, Bethesda, MD,_ 5 _Department of Pediatrics, University of Pennsylvania, Philadelphia, PA,_ 6 _Department of Pediatrics, The Ohio State University, Columbus, OH,_ 7 _Department of Pediatrics, Baylor College of Medicine, Houston, TX,_ 8 _Department of Pediatrics, University of Cincinnati, Cincinnati, OH,_ 9 _Department of Pediatrics, Harvard Medical School, Boston, MA,_ 10 _National Institutes of Health, Bethesda, MD,_ 11 _Department of Pathology and Immunology, Department of Molecular Biology, Washington University School of Medicine in St. Louis, Saint Louis, MO_

**9:15 AM** ( **298)** Extracorporeal Life Support in Pediatric Lung Transplant: A Single Center Experience; __ R. D. Vanderlaan1, M. Cypel2, H. Grassmann3, O. Honjo4, T. Humpl5, C. A. Caldarone4, M. Solomon3, R. Casas3, S. Azad2, A. Gueguerian6, S. Keshavjee2. 1 _Cardiac Surgery, University of Toronto, Toronto, ON, Canada,_ 2 _Thoracic Surgery, Lung Transplant Program, University Health Network, Toronto, ON, Canada,_ 3 _Respiratory Medicine, Lung Transplant Program, Hospital for Sick Children, Toronto, ON, Canada,_ 4 _Cardiovascular Surgery, Hospital for Sick Children, Toronto, ON, Canada,_ 5 _Cardiology, Hospital for Sick Children, Toronto, ON, Canada,_ 6 _Critical Care Medicine, Hospital for Sick Children, Toronto, ON, Canada_

8:00 AM - 9:30 AM

## ORAL SESSION 26: Philip K. Caves Award Candidate Presentations

Location:

Coronado A-C

Target Audience:

ALL

**Chairs:**

Stephan M. Ensminger, MD, DPhil, and Daniel Kreisel, MD, PhD

**8:00 AM** ( **299)** Donor-Derived Non-Classical Monocytes Recruit Recipient Neutrophils and Mediate Primary Lung Allograft Dysfunction; __ S. Chiu1, Z. Zheng1, M. Akbarpour1, R. Fernandez1, A. McQuattie-Pimentel1, P. Reyfman1, K. Anekalla1, D. Kreisel2, H. Perlman1, G. S. Budinger1, A. Misharin1, A. Bharat1. 1 _Northwestern University, Chicago, IL,_ 2 _Washington University, St. Louis, MO_

**8:15 AM** ( **300)** Extracorporeal Photopheresis Inhibits the Development of Obliterative Airway Disease and Promotes the Expansion of Intragraft Retinoic Acid-Producing CD103+ Dendritic Cells and Tregs; __ Z. Liu1, F. Liao1, X. Lin1, K. A. Toth1, X. Wang2, J. Zhu1, D. Scozzi1, A. S. Krupnick3, D. Kreisel1, R. Hachem4, J. M. Green5, A. E. Gelman1. 1 _Department of Surgery, Washington University in St. Louis, St. Louis, MO,_ 2 _Department of Medicine, University of Pittsburgh, Pittsburgh, PA,_ 3 _Department of Surgery, University of Virginia, Charlottesville, VA,_ 4 _Division of Pulmonary and Critical Care Medicine, Washington University in St. Louis, St. Louis, MO,_ 5 _Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, MO_

**8:30 AM** ( **301)** Increased Tumor Necrosis Factor-α Levels in Patients with Continuous-Flow Left Ventricular Assist Devices Mediate Vascular Instability and Are Associated with Higher Non-Surgical Bleeding; __ C. E. Tabit1, M. Coplan1, P. Chen1, V. Jeevanandam2, N. Uriel1, J. K. Liao1. 1 _Cardiology, The University of Chicago Medical Center, Chicago, IL,_ 2 _Surgery, The University of Chicago Medical Center, Chicago, IL_

**8:45 AM** ( **302)** Induction of Persistent Lung Transplant Tolerance by IL-2 Complex-Stimulated Regulatory T Cells In Vivo; __ Y. Yamada1, D. Impellizzieri2, T. Maeyashiki1, K. Brüstle1, L. Dubs1, J. Jang1, U. Karakus2, J. Woytschak2, I. Inci1, W. Weder1, O. Boyman2, W. Jungraithmayr1. 1 _Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland,_ 2 _Department of Immunology, University Hospital Zurich, Zurich, Switzerland_

**9:00 AM** ( **303)** Ischaemic Reperfusion Injury and Allograft Rejection Following DCD Heart Transplantation: Early Results; __ A. Page, M. Goddard, S. Messer, J. Dunning, J. Parameshwar, C. Lewis, A. Kydd, S. Pettit, Y. Abu-Omar, M. Berman, A. Ali, S. Tsui, S. Large. _Papworth Hospital NHS Foundation Trust, Cambridge, United Kingdom_

**9:15 AM** ( **304)** Utility of Droplet Digital PCR for the Detection of Aspergillus DNA in Bronchoalveolar Lavage and Exhaled Breath Condensate Samples from Lung Transplant Recipients; __ A. Bhimji1, L. G. Singer2, D. Kumar1, A. Humar1, C. Rotstein1, S. Keshavjee2, T. Mazzulli3, S. Husain1. 1 _Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada,_ 2 _Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada,_ 3 _Mount Sinai Hospital, Toronto, ON, Canada_

10:00 AM - 11:30 AM

## ORAL SESSION 27: The Leaking Gut - New Strategies for GI Bleeding in MCS

Location:

Seaport A-E

Target Audience:

MCS, HF, NHSAH, PHARM

**Chairs:**

Jan F Gummert, MD, PhD, and Sarah Schettle, PA-C

**10:00 AM** ( **305)** Endoscopic Evaluation in Patients with CF-LVADs with Gastrointestinal Bleeding: Are We Ready for a Paradigm Shift to Improve Care?; __ J. Axelrad, A. Pinsino, C. Brooks, P. Trinh, B. Cagliostro, F. Castagna, V. K. Topkara, A. R. Garan, L. A. Effner, H. Takayama, K. Takeda, Y. Naka, P. C. Colombo, M. Yuzefpolskaya, T. Gonda. _New York Presbyterian Hospital - Columbia University Medical Center, New York, NY_

**10:15 AM** ( **306)** Incidence and Risk Factors of Late Bleeding in Patients Enrolled in the PREVENT Study; __ R. John1, M. Keebler2, J. Stulak3, S. Emani4, C. Klodell5, S. Nathan6, A. Brieke7, N. Uriel8, J. Chin9, P. Eckman10, A. Nsair11, R. Agarwal12, T. Thenappan1, R. Adamson13, J. Chuang14, D. Farrar14, K. Sundareswaran14, J. Katz15. 1 _University of Minnesota, Minneapolis, MN,_ 2 _Vanderbilt University, Nashville, TN,_ 3 _Mayo Clinic, Rochester, MN,_ 4 _Ohio State University Medical Center, Columbus, OH,_ 5 _University of Florida, Gainesville, FL,_ 6 _Memorial Hermann - Texas Medical Center, Houston, TX,_ 7 _University of Colorado School of Medicine, Denver, CO,_ 8 _University of Chicago Medical Center, Chicago, IL,_ 9 _Sutter Medical Center, Sacramento, CA,_ 10 _Minneapolis Heart Institute, Minneapolis, MN,_ 11 _UCLA Medical Center, Santa Monica, CA,_ 12 _Allegheny General Hospital, Pittsburgh, PA,_ 13 _Sharp Memorial Hospital, San Diego, CA,_ 14 _St. Jude Medical, Pleasanton, CA,_ 15 _University of North Carolina, Chapel Hill, NC_

**10:30 AM** ( **307)** Predicting Recurrent GI Bleeding in Patients with CF-LVADs Using Pre-Implant Data; __ L. C. Lohmueller1, W. A. Alexander2, J. F. Antaki1. 1 _Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA,_ 2 _HEMA Biologics, LLC, Louisville, KY_

**10:45 AM** ( **308)** Comparison of Gastrointentional Bleeding Rates Between Axial Flow (HeartMate II) and Centrifugal (HeartWare) Flow Pumps at a Single Institution; __ M. Kawabori, C. Kurihara, T. Sugiura, L. Cunningham, A. B. Civitello, W. E. Cohn, O. H. Frazier, J. A. Morgan. _Texas Heart Institute, Baylor College of Medicine, Houston, TX_

**11:00 AM** ( **309)** Octreotide Reduces the Reoccurrence of Ventricular Assist Device Related Gastrointestinal Bleeding; __ K. B. Shah1, G. Sampath1, S. Emani2, M. K. Kanwar3, N. Uriel4, P. C. Colombo5, P. A. Uber1, M. L. Sears1, J. Chuang6, D. J. Farrar6, G. B. Smallfield1. 1 _Virginia Commonwealth Univ, Richmond, VA,_ 2 _Ohio State University, Columbus, OH,_ 3 _Allegheny General Hospital, Pittsburgh, PA,_ 4 _University of Chicago, Chicago, IL,_ 5 _Columbia University, New York, NY,_ 6 _St. Jude Medical, St. Paul, MN_

**11:15 AM** ( **310)** Pre-Implant Moderate-Severe Fibrosis on Liver Biopsy Predicts Adverse Outcomes After Mechanical Circulatory Support; __ R. Mohan, J. Neyer, J. Patel, M. Kittleson, T. Aintablian, R. Levine, D. Chang, L. Czer, J. Moriguchi, J. A. Kobashigawa, F. Arabia. _Cedars-Sinai Heart Institute, Los Angeles, CA_

10:00 AM - 11:30 AM

## ORAL SESSION 28: The Heart of the Matter: Cardiac Substrate in MCS Therapy

Location:

Grand Hall A

Target Audience:

MCS, HF

**Chairs:**

Stuart D. Russell, MD, and Jennifer A Cowger, MD, MS

**10:00 AM** ( **311)** Diurnal and Patient Activity Related Determinants of Aortic Valve Opening on Continuous Flow LVAD Support; __ R. Clifford1, D. Robson1, C. Gross2, F. Moscato2, H. Schima2, P. S. Macdonald1, P. Jansz1, C. S. Hayward1. 1 _Heart Failure and Transplant Unit, St Vincent's Hospital, Sydney, Australia,_ 2 _Medical University of Vienna, Vienna, Austria_

**10:15 AM** ( **312)** Increased Aortic Vascular Fibrosis with Prolonged Continuous-Flow Left Ventricular Assist Device Support; __ E. Dobrinskikh, S. Purohit, R. Dodson, R. Shtofman, S. Al-Juboori, M. Aftab, T. Reece, W. Cornwell, A. V. Ambardekar. _U Colorado, Aurora, CO_

**10:30 AM** ( **313)** Echocardiography Accurately Tracks Left Ventricular Unloading in Patients Supported with a HeartMate II LVAD Undergoing Ramp Testing; __ L. Letarte1, J. Amione-Guerra2, A. Bhimaraj1, B. Trachtenberg1, A. Guha1, G. Torre-Amione1, M. H. Park1, J. D. Estep1. 1 _Advanced Heart Failure and Transplant Cardiology, Houston Methodist Hospital, Houston, TX,_ 2 _Houston Methodist Hospital, Houston, TX_

**10:45 AM** ( **314)** 3D Echocardiography and Shape Analysis Changes Following Left Ventricular Assist Device Implantation: The Effect of Unloading on Reverse Remodeling; __ G. Sayer1, D. Medvedofsky1, S. Adatya1, N. Sarswat1, G. H. Kim1, E. Kruse1, T. Ota2, V. Jeevanandam2, D. Burkhoff3, R. Lang1, N. Uriel1. 1 _Medicine, University of Chicago, Chicago, IL,_ 2 _Cardiothoracic Surgery, University of Chicago, Chicago, IL,_ 3 _Medicine, Columbia University, New York, NY_

**11:00 AM** ( **315)** Prevalence of Myocardial Fibrosis by LVAD Apical Core Biopsy and Correlation with Other Markers of Myocardial Recovery; __ J. N. Schultz1, R. John2, C. M. Martin3, M. Pritzker3, E. Missov3, T. Thenappan3, R. Cogswell3. 1 _Department of Medicine, University of Minnesota, Minneapolis, MN,_ 2 _Department of Surgery, Division of Cardiovascular and Thoracic Surgery, University of Minnesota, Minneapolis, MN,_ 3 _Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN_

**11:15 AM** ( **316)** Coronary Artery Remodeling and Fibrosis with Continuous-Flow Left Ventricular Assist Device Support; __ A. V. Ambardekar, M. Weiser-Evans, M. Li, M. Aftab, T. Reece, P. Buttrick, K. Moulton. _University of Colorado, Aurora, CO_

10:00 AM - 11:30 AM

## ORAL SESSION 29: Donor Utilization and Allocation in Heart Transplantation: Lessons to Learn

Location:

Grand Hall B

Target Audience:

HTX, HF

**Chairs:**

Joseph G Rogers, MD, and Marta Farrero Torres, MD, PhD

**10:00 AM** ( **317)** Great Variability in Donor Heart Acceptance Practices Across the USA; __ K. Khush, R. Ball. _Stanford University, Stanford, CA_

**10:15 AM** ( **318)** Supply and Demand: Disparities Across UNOS Regions; __ D. A. Baran1, H. Copeland2, G. Katlaps3, B. Dharmaraj3, S. Kapoor1, J. Pieretti1, C. Gidea1, M. J. Zucker1, T. Martin1, M. Camacho1, J. Copeland3. 1 _Transplant Center, Newark Beth Israel Medical Ctr, Livingston, NJ,_ 2 _Dept of Cardiac Surgery, Hunter Holmes McGuire Veterans Administration Medical Center, Richmond, VA,_ 3 _McGuire VA Medical Center, Richmond, VA_

**10:30 AM** ( **319)** Is There an Optimal Acceptance Rate for Adult Transplant Centers?; __ Y. Radzi1, F. Zafar1, R. Rizwan1, C. Park1, J. Tweddell1, A. Simeone2, L. Louis IV1, D. Morales1. 1 _Division of Cardiothoracic Surgery, Cincinnati Children's Hospital, Cincinnati, OH,_ 2 _Division of Cardiac Surgery, University of Cincinnati, Cincinnati, OH_

**10:45 AM** ( **320)** Trends in Simultaneous Heart-Kidney Transplantation: An Analysis of UNOS/OPTN Data from 2000 to 2015; __ R. C. Givens, V. K. Topkara, S. W. Restaino, F. Latif, Y. Naka, H. Takayama, K. Takeda, P. C. Colombo, M. A. Farr. _Medicine, Columbia University Medical Center, New York, NY_

**11:00 AM** ( **321)** The New Heart Allocation System: Implications on Patients with Restrictive Cardiomyopathy in the UNOS Registry; __ L. Sridharan1, R. Givens1, K. Takeda2, A. R. Garan1, M. Yuzefpolskaya1, F. Latif1, S. Restaino1, J. Haythe1, J. Ginns1, D. Mancini3, Y. Naka2, P. Colombo1, M. Maurer1, H. Takayama2, V. K. Topkara1. 1 _Cardiology, Columbia University, New York, NY,_ 2 _Cardiothoracic Surgery, Columbia University, New York, NY,_ 3 _Cardiology, Mount Sinai, New York, NY_

**11:15 AM** ( **322)** Effect of Left Ventricular Dysfunction on Utilization of Donor Hearts; __ D. Tryon1, N. W. Hasaniya1, L. L. Bailey1, D. S. Juma2, B. Jabo2, A. J. Razzouk1, D. G. Rabkin1. 1 _Cardiovascular and Thoracic Surgery, Loma Linda University Medical Center, Loma Linda, CA,_ 2 _School of Public Health, Research Consulting Group, Loma Linda University Medical Center, Loma Linda, CA_

10:00 AM - 11:30 AM

## ORAL SESSION 30: Novel Mechanisms in Chronic Lung Allograft Dysfunction

Location:

Grand Hall C

Target Audience:

LTX, BSTR, ID, PATH, PHARM

**Chairs:**

Mark Greer, MB Bch, and David Weill, MD

**10:00 AM** ( **323)** Decreased Donor PBMC and Allograft Telomere Length Are Associated with Shorter CLAD-Free Survival; __ H. E. Faust1, J. A. Golden2, R. Rajalingam3, A. S. Wang3, G. Green2, S. R. Hays2, J. Kukreja3, J. P. Singer2, P. J. Wolters2, J. R. Greenland2. 1 _Medicine, Perelman School of Medicine, Philadelphia, PA,_ 2 _Medicine, U. California SF, San Francisco, CA,_ 3 _Surgery, U. California SF, San Francisco, CA_

**10:15 AM** ( **324)** Novel Mechanism for the Increased Risk for Chronic Lung Allograft Dysfunction by Respiratory Viral Infections Following Human Lung Transplantation; __ M. Gunasekaran1, A. Limaye2, M. Sharma1, S. Bansal1, R. Walia1, M. Smith1, R. M. Bremner1, T. Mohanakumar1. 1 _St. Joseph's Hospital & Medical Center, Phoenix, AZ, _2 _University of Washington, Seattle, WA_

**10:30 AM** ( **325)** The Role of the Mesothelium in rCLAD After Lung Transplantation; __ A. Sacreas, S. E. Verleden, H. Bellon, E. Vandermeulen, T. Heigl, A. Van Herck, G. M. Verleden, R. Vos, B. M. Vanaudenaerde. _KU Leuven, Leuven, Belgium_

**10:45 AM** ( **326)** Antibodies to Human Leukocyte Antigen Class I and Lung Associated Self-Antigens, K-alpha-1 Tubulin and Collagen V Induces Exosomes Containing Self-Antigens from Human Primary Airway Epithelial and Endothelial Cells; __ M. Gunasekaran1, M. Sharma1, S. Bansal1, R. Walia1, R. M. Bremner1, M. Smith1, T. Mohanakumar2. 1 _St. Joseph's Hospital & Medical Center, Phoenix, AZ, _2 _St. Joseph's, Phoenix, AZ_

**11:00 AM** ( **327)** Exosomes Isolated from Lung Transplant Recipients Diagnosed with Bronchiolitis Obliterans Syndrome, But Not Stable, Can Induce Immune Responses to Lung Associated Self-Antigens, K-alpha-1 Tubulin and Collagen V; __ M. Gunasekaran, M. Sharma, S. Bansal, R. Walia, M. Smith, R. M. Bremner, T. Mohanakumar. _St. Joseph's Hospital & Medical Center, Phoenix, AZ_

**11:15 AM** ( **328)** Increasing Frequency of CD127low Regulatory T Cells Early After Lung Transplantation Is Associated with Freedom from Chronic Lung Allograft Rejection and Survival in 503 Patients; __ F. Ius1, J. Salman1, A. Knöfel1, T. Nakagiri1, W. Sommer1, T. Siemeni1, C. Kühn1, M. Avsar1, D. Böthig1, T. Welte2, A. Haverich1, I. Tudorache1, G. Warnecke1. 1 _Department of Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany,_ 2 _Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany_

10:00 AM - 11:30 AM

## ORAL SESSION 31: Saved by the Bell: Overcoming Adherence and Frailty

Location:

Grand Hall D

Target Audience:

NHSAH, ALL

**Chairs:**

Meloneysa Hubbard, MSN, CRNP, CCTC, and Christiane Kugler, PhD

**10:00 AM** ( **329)** The Use of Transplant Medicines IT Tool in Supporting Patients' Knowledge of Immunosuppressant Medications; __ L. Alsarraf1, R. Betmouni1, N. Bidad2, A. Reed1, O. Dar1, A. Simon1, H. Lyster1. 1 _Royal Brompton & Harefield NHS Foundation Trust, Middlesex, United Kingdom, _2 _University College London, London, United Kingdom_

**10:15 AM** ( **330)** Practice Patterns to Improve Pre- and Post-Transplant Medication Adherence in Heart Transplant Centers: A Secondary Data Analysis of the International Bright Study; __ S. M. De Geest. _Public Health, University of Basel, Basel, Switzerland_

**10:30 AM** ( **331)** A Trajectory Analysis of Adherence to Recommended Exercise Following Lung Transplantation; __ M. Alrawashdeh, J. Choi, A. DeVito Dabbs. _School of Nursing, University of Pittsburgh, Pittsburgh, PA_

**(332)** WITHDRAWN

**10:45 AM** ( **448)** FOCUS for Pediatric Heart Transplant: A Trauma-Informed, Family-Centered, Resilience Enhancing Intervention; __ K. Wijesekera1, N. D. Emerson1, M. S. Cortez1, J. Alejos2, P. Lester1. 1 _Psychiatry and Biobehavioral Sciences, UCLA, Los Angeles, CA,_ 2 _Pediatric Cardiology, UCLA, Los Angeles, CA_

**11:00 AM** ( **333)** Quadriceps Strength Predicts Estimates of Physical Activity Post-Heart Transplantation; __ R. L. Kelly1, J. R. Walsh1, J. D. Paratz2, S. T. Yerkovich3, S. McKenzie3, N. R. Morris2. 1 _Physiotherapy Department, The Prince Charles Hospital, Chermside, Australia,_ 2 _School of Allied Health Sciences, Griffith University, Gold Coast, Australia,_ 3 _School of Medicine, The University of Queensland, Brisbane, Australia_

**11:15 AM** ( **334)** Increased Perceived Stress and Fatigue are Associated with Worse Quality of Life in Patients with a Left Ventricular Assist Device; __ M. A. Abshire1, P. M. Davidson1, S. Desai2, C. Budhathoki1, S. D. Russell1, C. Dennison Himmelfarb1. 1 _Johns Hopkins University, Baltimore, MD,_ 2 _Inova Fairfax Hospital, Falls Church, VA_

10:00 AM - 11:30 AM

## ORAL SESSION 32: The Tell Tale Heart: From Signals to Biomarkers

Location:

Seaport F-H

Target Audience:

BSTR, HF, HTX, MCS, NHSAH, PATH, PEDS, PH, PHARM

**Chairs:**

Kyung-Hee Kim, MD, and Tomoko S Kato, MD, PhD

**10:00 AM** ( **335)** Complementary Intragraft and Peripheral Blood Mononuclear Cell Gene Co-Expression Network Analysis of ISHLT Driven versus Unsupervised Molecular Classification; __ E. Chang1, G. Fishbein1, M. Bakir1, D. Liem1, S. Litovsky2, J. Tallaj2, G. Bondar1, E. Reed1, M. Deng1, E. Tabak3, M. Cadeiras1. 1 _Medicine, UCLA, Los Angeles, CA,_ 2 _Medicine, University of Alabama at Birmingham, Birmingham, AL,_ 3 _Courant Institute of Mathematical Sciences, New York University, New York, NY_

**10:15 AM** ( **336)** Pre-Transplant Serum Exosome and Functional Analysis in Primary Graft Dysfunction; __ B. Fine1, E. Zorn1, E. Chen2, G. Vunjak-Novakovic3, P. Colombo1. 1 _Medicine, Columbia University, New York, NY,_ 2 _Pharmacology, Columbia University, New York, NY,_ 3 _Biomedical Engineering, Columbia University, New York, NY_

**10:30 AM** ( **337)** Antibody Response to Non-Self Blood Group A-Antigen Is Dependent on CD4 T Cells and Co-Engagement with Foreign Protein; __ I. Adam1, B. Motyka1, J. Pearcey1, K. Tao1, P. J. Cowan2, L. J. West1. 1 _Dept. Pediatrics, Alberta Transplant Institute, Canadian National Transplant Research Program, University of Alberta, Edmonton, AB, Canada,_ 2 _Immunology Research Centre, St Vincent's Hospital, University of Melbourne, Melbourne, Australia_

**10:45 AM** ( **338)** Gene Expression in Pediatric Myocardium: Pulsatile- vs. Continuous-Flow VAD Support; __ I. Adachi1, M. Zhang2, S. Burki1, D. L. Morales3, A. Jeewa4, D. Kearney5, L. Wadhwa1, C. D. Fraser, Jr.1, J. F. Martin6. 1 _Congenital Heart Surgery, Texas Children's Hospital, Houston, TX,_ 2 _Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX,_ 3 _Congenital Heart Surgery, Cincinatti Children's Hospital, Cincinnati, OH,_ 4 _Pediatric Cardiology, Texas Children's Hospital, Houston, TX,_ 5 _Pathology, Texas Children's Hospital, Houston, TX,_ 6 _Molecular Physiology and Biophysics and Cardiovascular Research Institute, Baylor College of Medicine, Houston, TX_

**11:00 AM** ( **339)** PPARgamma Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells; __ L. Calvier1, P. Chouvarine1, M. M. Mozes2, G. Hansmann1. 1 _Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany,_ 2 _Pathophysiology, Semmelweis University, Budapest, Hungary_

**11:15 AM** ( **340)** Voltage-Gated Ca2+ Influx into Coronary Artery Smooth Muscle Is Decreased in Ischemic versus Non-Ischemic Cardiomyopathy - The First Evidence from Human Transplant Cardiectomy Samples; __ R. J. Chen1, M. Alloosh2, J. K. Badin2, M. Sturek2, I. Wang1, T. Wozniak1, Z. A. Hashmi1. 1 _Cariothoracic Transplantation Surgery, Indiana University - Methodist Hospital, Indianapolis, IN,_ 2 _Department of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, IN_

10:00 AM - 11:30 AM

## ORAL SESSION 33: PATH to Better Outcomes: Diagnostics in Heart and Lung Transplantation

Location:

Coronado A-C

Target Audience:

PATH, BSTR, HTX, LTX, PEDS

**Chairs:**

Martin J Goddard, FRCS MRCPa, and Robert F. Padera, MD, PhD

**10:00 AM** ( **341)** Widening of Alveolar Septa in Transbronchial Biopsies with Antibody-Mediated Rejection (AMR): Preliminary Data from Multicenter Pilot Study; __ F. Calabrese1, S. Hirschi2, M. Chenard2, M. Montero-Fernandez3, D. Neil4, W. Timens5, E. Verbeken6, E. Perissinotto1, F. Lunardi1, E. Cozzi7, D. J. Levine8, M. Goddard9. 1 _University of Padova, Padova, Italy,_ 2 _University of Strasbourg, Strasbourg, France,_ 3 _Royal Brompton & Harefield NHS, London, United Kingdom, _4 _Queen Elizabeth Hospital, Birmingham, United Kingdom,_ 5 _University of Groningen, Groningen, Netherlands,_ 6 _University of Leuven, Leuven, Belgium,_ 7 _Padova University Hospital, Padova, Italy,_ 8 _University of Texas Health Science Center, San Antonio, TX,_ 9 _Papworth Hospital, Papworth, United Kingdom_

**10:15 AM** ( **342)** Prospective Study of Histopathologic Features of Cardiac Antibody-Mediated Rejection and Correlation with Donor Specific Antibodies and Graft Dysfunction; __ A. C. Roden1, J. J. Maleszewski1, P. Lin1, S. M. Jenkins2, M. Gandhi2, N. Pereira2, M. Aubry1. 1 _Laboratory Medicine & Pathology, Mayo Clinic Rochester, Rochester, MN, _2 _Mayo Clinic Rochester, Rochester, MN_

**10:30 AM** ( **343)** Endothelial Cell Activation in a Mouse Model of Cardiac Antibody-Mediated Rejection; __ M. Racape1, J. Duong Van Huyen1, C. Chen2, A. Loupy1, O. Thaunat2, P. Bruneval1. 1 _U970, INSERM-University Paris Descartes, Paris, France,_ 2 _U1111, INSERM-University Lyon 1 Claude Bernard, Lyon, France_

**10:45 AM** ( **344)** Liquid Biopsies: Non-Invasive Rejection Detection After Heart Transplantation; __ L. Hofste1, A. Vink1, J. van Kuik1, E. Siera-de Koning1, F. Ahmadi1, N. de Jonge2, R. de Weger1, M. Huibers1. 1 _Pathology, UMC Utrecht, Utrecht, Netherlands,_ 2 _Cardiology, UMC Utrecht, Utrecht, Netherlands_

**11:00 AM** ( **345)** Changes in Myocardial Microvascularisation After Heart Transplantation and During Cardiac Allograft Vasculopathy ; __ M. Huibers1, F. van Pijpen1, H. Kirkels2, N. de Jonge2, A. Vink1, R. de Weger1. 1 _Pathology, UMC Utrecht, Utrecht, Netherlands,_ 2 _Cardiology, UMC Utrecht, Utrecht, Netherlands_

**11:15 AM** ( **346)** Late Graft Dysfunction After Pediatric Heart Transplantation Is Associated with Fibrosis and Decreased Capillary Density by Automated, Whole-Slide Imaging; __ B. Feingold1, J. Picarsic2, A. Lesniak3, M. Wood-Trageser3, B. Popp3, A. J. Demetris3. 1 _Pediatric Cardiology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA,_ 2 _Pathology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA,_ 3 _Pathology, University of Pittsburgh, Pittsburgh, PA_

1:30 PM - 3:30 PM

## SYMPOSIUM 24: Aiming Off Target: Non-Cardiac Consequences of LVAD Support

Location:

Seaport A-E

Target Audience:

MCS, BSTR, HF

**Chairs:**

Mustafa Toma, MD, and Emma Birks, MD, PhD

**Session Summary:** The relevance of non-cardiac consequences of LVAD support is being increasingly recognized. Many of these "off-target-organ" effects have largely driven the morbidity and mortality of LVAD-supported patients, and these will become more relevant with the rise of the destination therapy population. In this symposium, each speaker will discuss alterations in a different organ system with LVAD support and future directions for research and technologic development to address these alterations.

1:30 PM

Continuous-Flow Effects on the Systemic Vasculature and Endothelium

Amrut V Ambardekar, MD, University of Colorado, Aurora, CO, USA

**1:45 PM** _Q &A_

1:50 PM

LVAD Effects on Skeletal Musculature and Exercise Capacity

Finn Gustafsson, MD, PhD, Rigshospitalet, Copenhagen, Denmark

**2:05 PM** _Q &A_

2:10 PM

Renal Function with LVAD Support

Meredith A Brisco, MD MSCE, Temple University, Philadelphia, PA, USA

**2:25 PM** _Q &A_

2:30 PM

Hematologic Pertubations Caused by Mechanical Support

Anna L Meyer, MD, Leipzig Heart Center, Leipzig, Germany

**2:45 PM** _Q &A_

2:50 PM

Neuropsychological Function in Long-term LVAD Patients

Ralph Petrucci, MD, Drexel University College of Medicine, Philadelphia, PA, USA

**3:05 PM** _Q &A_

3:10 PM

Gastrointestinal Physiologic Changes Associated With Continuous-Flow Pumps

Brian Houston, MD, Medical University of South Carolina, Charleston, SC, USA

**3:25 PM** _Q &A_

1:30 PM - 3:30 PM

## SYMPOSIUM 25: Dealing with Antibodies Before and After Heart Transplant: Do We Have New Arrows in our Quiver?

Location:

Grand Hall A

Target Audience:

ALL

**Chairs:**

Michael Shullo, PharmD, and Luciano Potena, MD, PhD

**Session Summary:** This session will provide an overview of the current management strategies for sensitized patients pre- and post-transplant by discussing desensitization pharmacotherapy, long-term management and monitoring, key challenges and strategies, immunogenetic and non-HLA considerations, and possible downstream implications on target cells, incorporating the newest research-based evidence supplemented with experience from seasoned multidisciplinary clinicians.

1:30 PM

Overview of the Management of the Sensitized Heart Transplant Candidate and Recipient

Monica Colvin, MD, University of Michigan, Ann Arbor, MI, USA

**1:45 PM** _Q &A_

1:50 PM

Strategies for Desensitization of the Heart Transplant Candidate

Laura M. Lourenco, PharmD, University of Chicago Medicine, Chicago, IL, USA

**2:05 PM** _Q &A_

2:10 PM

Downstream Implications of Desensitization

Rajalingam Raja, PhD, UCSF Medical Center, San Francisco, CA, USA

**2:25 PM** _Q &A_

2:30 PM

DEBATE (PRO): No Time to Wait: Proceed to Heart Transplant with Low Level Donor Specific Antibodies

Barbara Pisani, MD, Wake Forest Medical Center, Winston-Salem, NC, USA

2:45 PM

DEBATE (CON): No Time to Wait: Proceed to Heart Transplant with Low Level Donor Specific Antibodies

Lee R. Goldberg, MD, MPH, University of Pennsylvania, Philadelphia, PA, USA

3:00 PM

DEBATE (PRO): Asymptomatic Donor Specific Antibodies After Transplant: Everyone Should Be Treated

Sharon Chih, MD, University of Ottawa Heart Institute, Ottawa, ON, Canada

3:15 PM

DEBATE (CON): Asymptomatic Donor Specific Antibodies After Transplant: Everyone Should Be Treated

Palak Shah, MD, MS, Inova Fairfax Hospital, Falls Church, VA, USA

1:30 PM - 3:30 PM

## SYMPOSIUM 26: Making Every Heart Count

Location:

Grand Hall B

Target Audience:

HTX, EEP, HF, HTX

**Chairs:**

Kiran K. Khush, MD, and Jason W Smith, MD

**Session Summary:** This symposium focuses on donor heart utilization, from use of expanded criteria donors to improved stewardship of donor hearts, reducing waste of potentially usable hearts and breaking open the doors of DCD heart procurement.

1:30 PM

Is The Expanded Criteria Donor the New Standard Criteria Donor?

Andre R Simon, MD, PhD, Harefield Hospital, London, United Kingdom

**1:45 PM** _Q &A_

1:50 PM

Can We Revive the DCD Heart?

Stephen Large, FRCS, Papworth Hospital, Cambridge, United Kingdom

**2:05 PM** _Q &A_

2:10 PM

Resource Stewardship in Donor Selection

Michael Pham, MD, California Pacific Medical Center, San Francisco, CA, USA

**2:25 PM** _Q &A_

2:30 PM

The Public Health Service (PHS) Increased Risk Donor: What Is the Real Risk of Infection?

Michael Ison, MD, Northwestern University, Chicago, IL, USA

**2:45 PM** _Q &A_

2:50 PM

Evaluation of the Heart at Time of Donor Procurement

William E Stansfield, MD, Toronto General Hospital, Toronto, ON, Canada

**3:05 PM** _Q &A_

3:10 PM

Getting The Heart Home - How to Procure the Donor Heart

Hannah Copeland, MD, VA McGuire Medical Center/Virginia Commonwealth University, Richmond, VA, USA

**3:25 PM** _Q &A_

1:30 PM - 3:30 PM

## SYMPOSIUM 27: Bench to Bedside: How Advances in Immunology Shape the Care of Today's Lung Transplant Recipients

Location:

Grand Hall C

Target Audience:

LTX, BSTR, HTX, ID, NHSAH, PATH, PEDS, PHARM

**Chairs:**

Ciara M Shaver, MD, and Andrew J Fisher, PhD FRCP

**Session Summary:** Recent advances in immunology have important implications for modern day clinical care. This session will highlight some important scientific advances in genomics and immunology with direct applicability to clinical issues including immunosuppression, graft surveillance, drug dosing, and antibody mediated rejection. This session will help to bridge the gap between translational immunology research and current clinical practice.

1:30 PM

The Immunobiology of Lung Transplantation: From Bench to Bedside

Rebecca A Shilling, MD, University of Chicago, Chicago, IL, USA

**1:50 PM** _Q &A_

1:54 PM

The Quest for Biomarkers for Acute and Chronic Lung Rejection: Where Are We Now?

John R Greenland, MD, PhD, UCSF Medical Center, San Francisco, CA, USA

**2:14 PM** _Q &A_

2:18 PM

Tackling the Immune System: Novel Biologicals and Immunomodulators in Lung Transplant Recipients

Stephen Juvet, MD, PhD, Toronto General Research Institute, Toronto, ON, Canada

**2:38 PM** _Q &A_

2:42 PM

Antibody-Targeted Therapies in Lung Transplantation: When and How to Use?

Ramsey R Hachem, MD, Washington University School of Medicine, St. Louis, MO, USA

**3:02 PM** _Q &A_

3:06 PM

Targeting Non-Immune Cells: Novel Treatment Options in Lung Transplantation

Daniel Chambers, MBBS, MRCP, FRACP, MD, The Prince Charles Hospital, Brisbane, Australia

**3:26 PM** _Q &A_

1:30 PM - 3:30 PM

## SYMPOSIUM 28: Great Debates in Pulmonary Hypertension

Location:

Grand Hall D

Target Audience:

PH, ALL

**Chairs:**

Teresa De Marco, MD, FACC, and Paul A Corris, MB FRCP

**Session Summary:** The diagnosis and management of pulmonary hypertension is steadily being refined by ongoing investigations in the field. However, knowledge gaps and challenges still remain. This session will explore in case and debate format controversial diagnostic and management dilemmas beyond accepted practice. Topics include adding additional Pulmonary Arterial Hypertension (PAH) specific therapy in a stable patient, treatment of borderline pulmonary hypertension, and managing pulmonary hypertension complicated by Interstitial Lung Disease (ILD).

1:30 PM

Case Presentation: To Treat or Not To Treat...Interstitial Lung Disease (IDL)-PH

Christopher King, MD, FACP, FCCP, Inova Fairfax Hospital, Falls Church, VA, USA

1:35 PM

DEBATE (PRO): Pulmonary Hypertension Due to Lung Disease Should Be Treated with PAH Specific Therapies

Steven D. Nathan, MD, Inova Fairfax Hospital, Falls Church, VA, USA

1:50 PM

DEBATE (CON): Pulmonary Hypertension Due to Lung Disease Should Be Treated with PAH Specific Therapies

Marius Hoeper, MD, Hannover Medical School, Hannover, Germany

2:05 PM

Case Presentation: To Treat or Not To Treat...Borderline PAH

Richa Agarwal, MD, Allegheny General Hospital, Pittsburgh, PA, USA

2:10 PM

DEBATE (PRO): "Borderline" PAH Should Be Treated with PAH Specific Therapy

Bradley Maron, MD, Brigham and Women's Hospital, Boston, MA, USA

2:25 PM

DEBATE (CON): "Borderline" PAH Should Be Treated with PAH Specific Therapy

Jean-Luc Vachiery, MD, Erasme University Hospital - ULB, Brussels, Belgium

2:40 PM

Case Presentation: "I'm doing fine Doc, do I really need another pill?"

Roberto Badagliacca, MD, University of Rome Sapienza, Rome, Italy

2:45 PM

DEBATE (PRO): My Patient with PAH is Clinically Stable on Monotherapy: I Should Escalate to Dual or Triple Therapy

Rogerio Souza, MD, University of Sao Paulo, Sao Paulo, Brazil

3:00 PM

DEBATE (CON): My Patient with PAH is Clinically Stable on Monotherapy: I Should Escalate to Dual or Triple Therapy

Veronica Franco, MD, Ohio State University, Columbus, OH, USA

**3:15 PM** _Panel Discussion_

1:30 PM - 3:30 PM

## SYMPOSIUM 29: How to Mend a Broken Heart: Approaches for Cardiac Regeneration

Location:

Seaport F-H

Target Audience:

BSTR, HF, HTX, PATH, PHARM

**Chairs:**

Lori West, MD, DPhil, and Daniel TS Reichart, MD

**Session Summary:** This session provides an overview of mechanisms of heart failure and different experimental approaches for cardiac regeneration. Implications for multipotent stem cell therapies are presented, followed by cell independent strategies to cardiac regeneration. Furthermore, the potential of pluripotent stem cells and stem cell-derived cardiomyocytes, as well as myocardial tissue engineering approaches, will be discussed.

1:30 PM

Mechanisms of Heart Failure and Experimental Therapeutic Options

Claudius Mahr, DO, University of Washington, Seattle, WA, USA

**1:45 PM** _Q &A_

1:50 PM

Multipotent Stem Cells and Cardiac Progenitors in Clinical Trials

Joshua Hare, MD, Miller School of Medicine, Miami, FL, USA

**2:05 PM** _Q &A_

2:10 PM

MicroRNAs and Cell Independent Strategies for Cardiac Regeneration

Pradeep Mammen, MD, UT Southwestern Medical Center, Dallas, TX, USA

**2:25 PM** _Q &A_

2:30 PM

Cardiac Cell Injection for Heart Failure: Pluripotent Stem Cells (PSC) and Stem Cell-Derived Cardiomyocytes

Tobias Deuse, MD, PhD, UCSF Medical Center, San Francisco, CA, USA

**2:45 PM** _Q &A_

2:50 PM

Myocardial Tissue Engineering: Where Are We Now and Where Are We Heading?

Simon Pecha, MD, University Heart Centre Hamburg, Hamburg, Germany

**3:05 PM** _Q &A_

3:10 PM

Pluripotent Stem Cells: Hurdles and Perspectives on the Way to Clinical Application

Doris Taylor, MD, Texas Heart Institute, Houston, TX, USA

**3:25 PM** _Q &A_

1:30 PM - 3:30 PM

## SYMPOSIUM 30: E-Health, Wearables, Social Media and Big Data in Transplantation: Fancy Toys or True Care Innovations?

Location:

Coronado A-C

Target Audience:

NHSAH, ALL

**Chairs:**   
Deborah Page, NP, and Steve Ivulich, PharmD

**Session Summary:** The purpose of this symposium is to discuss the state-of-the-art of e-health technology (telemedicine, telehealth and interactive health technology applications) in delivering care (e.g. long-distance care, self- management support) in end-stage organ disease, LVAD and transplantation. In addition, interactive communication options via social media for public involvement as well as research dissemination will be reviewed. Moreover the value of big data for transplantation will be explored.

1:30 PM

The Many Faces of E-health: An Overview

Fabienne Dobbels, MSc, PhD, University of Leuven, Leuven, Belgium

**1:45 PM** _Q &A_

1:50 PM

The Importance of Involving End-Users When Designing Interactive Health Technology Applications for Self-Management Support

Annette Devito-Dabbs, PhD, RN, ACNS-BC, FAAN, University of Pittsburgh School of Nursing, Pittsburgh, PA, USA

**2:05 PM** _Q &A_

2:10 PM

The ABCs of Social Media

Mary N. Walsh, MD, St. Vincent Hospital, Indianapolis, IN, USA

**2:25 PM** _Q &A_

2:30 PM

Closer to the Heart: The Impact of Distance to Care and Remote Care

Tam Khuu, PharmD, UCLA Medical Center, Los Angeles, CA, USA

**2:45 PM** _Q &A_

2:50 PM

Big Data: Big Impact

Josef Stehlik, MD, MPH, University of Utah School of Medicine, Salt Lake City, UT, USA

**3:05 PM** _Q &A_

3:10 PM

New Ethical and Legal Challenges Surrounding E-health in Transplantation

JiYeon Choi, PhD, RN, University of Pittsburgh School of Nursing, Pittsburgh, PA, USA

**3:25 PM** _Q &A_

4:00 PM - 5:30 PM

## ORAL SESSION 34: Short-Term MCS for Shock: New Paradigms

Location:

Seaport A-E

Target Audience:

MCS, HF, HTX, NHSAH

**Chairs:**

Ashish S. Shah, MD, and Pascal N. Leprince, MD, PhD

**4:00 PM** ( **347)** Extra Corporeal Membrane Oxygenation (ECMO) as a Bridge to Adult Heart Transplantation: Bridge to Bridge Strategy vs Direct ECMO Bridge Strategy (UNOS Analysis); __ B. Hannawi1, J. Estep1, D. Nguyen2, E. Graviss2, B. Trachtenberg1, A. Bhimaraj1, M. Park1, B. A. Bruckner3, A. Guha1. 1 _Cardiolovascular Disease, Houston Methodist Hospital, Houston, TX,_ 2 _Houston Methodist Research Institute, Houston, TX,_ 3 _Houston Methodist Hospital, Houston, TX_

**4:15 PM** ( **348)** Hemodynamic Effects and Clinical Response to Intra-Aortic Balloon Pump in Chronic Heart Failure Patients with Cardiogenic Shock; __ J. Fried, A. Nair, V. K. Topkara, A. Masoumi, K. Clerkin, P. C. Colombo, M. Yuzefpolskaya, K. Takeda, H. Takayama, Y. Naka, A. R. Garan. _Columbia University, New York, NY_

**4:30 PM** ( **349)** Incidence and Outcomes of Acute Circulatory Support Prior to Heart Transplantation; __ D. Ouyang, G. Gulati, R. Ha, D. Banerjee. _Medicine, Stanford, Palo Alto, CA_

**4:45 PM** ( **350)** Clinical Outcomes and Left Ventricular Unloading with Intra-Aortic Balloon Pump During Extracorporeal Life Support; __ S. Tepper, M. F. Masood, M. Baltazar Garcia, M. Pisani, A. Ahmed, A. Khan, A. Itoh. _Washington University School of Medicine in St. Louis, Saint Louis, MO_

**5:00 PM** ( **351)** Contemporary ECMO Therapy for Postcardiotomy Shock: From REgiStry for Cardiogenic Shock: Utility and Efficacy of Device Therapy (RESCUE); __ H. Takayama1, J. Han1, M. Baltazar-Garcia2, M. Lucas3, M. Kai4, M. Camacho5, B. Sun6, D. Ranney7, M. A. Daneshmand7, A. Itoh2. 1 _Division of Cardiothoracic Surgery, Columbia University Medical Center, New York, NY,_ 2 _Division of Cardiothoracic Surgery, Washington University in St. Louis, St. Louis, MO,_ 3 _Department of Cardiothoracic Surgery, University of Colorado, Denver, CO,_ 4 _Department of Cardiothoracic Surgery, Westchester Medical Center, Valhalla, NY,_ 5 _Department of Cardiothoracic Surgery, Newark Beth Israel Medical Center, Newark, NJ,_ 6 _Minneapolis Heart Institute, Minneapolis, MN,_ 7 _Division of Cardiothoracic Surgery, Duke University Medical Center, Durham, NC_

**5:15 PM** ( **352)** Clinical Outcomes of Impella Microaxillary Pumps When Used in Patients with Cardiogenic Shock Bridged Successfully to Durable Mechanical Circulatory Support and Cardiac Transplantation; __ R. Cheng, D. Ramzy, B. Azarbal, F. Esmailian, D. Geft, D. H. Chang, E. Passano, L. Czer, J. A. Kobashigawa, J. Moriguchi, F. Arabia. _Cedars-Sinai Heart Institute, Los Angeles, CA_

4:00 PM - 5:30 PM

## ORAL SESSION 35: Heart Failure in MCS

Location:

Grand Hall A

Target Audience:

MCS, HF, HTX, PH

**Chairs:**

Ahmet Kilic, MD, and Anna L Meyer, MD

**4:00 PM** ( **353)** Does Inotrope Dependence Make a Difference in Outcome in Patients Receiving Left Ventricular Assist Device? Comparison Between INTERMACS Profiles 3 vs 4/5 from the INTERMACS Registry; __ S. M. Joseph1, S. A. Hall1, B. Lima1, J. O. Robertson2, D. C. Naftel3, S. Myers3, J. K. Kirklin4, S. C. Silvestry5. 1 _Center for Advanced Heart and Lung Disease, Baylor University Medical Center, Dallas, TX,_ 2 _Washington University, St. Louis, MO,_ 3 _University of Alabama, Birmingham, AL,_ 4 _Surgery, University of Alabama, Birmingham, AL,_ 5 _Surgery, Florida Hospital Center, Orlando, FL_

**4:15 PM** ( **354)** Vasoactive-Inotropic Score Is Associated with In-Hospital Mortality in Continuous Flow Left Ventricular Assist Device Patients; __ J. Han1, H. Takayama1, P. A. Kurlansky1, A. R. Garan2, M. Yuzefpolskaya2, V. K. Topkara2, P. C. Colombo2, Y. Naka1, K. Takeda1. 1 _Division of Cardiothoracic Surgery, Columbia University Medical Center, New York, NY,_ 2 _Division of Cardiology, Columbia University Medical Center, New York, NY_

**4:30 PM** ( **355)** The Duration of Inotropic Support and Survival After Left Ventricular Assist Device; __ E. Grandin1, D. Mooney1, K. Kennedy2, M. S. Kiernan3, R. D. Kociol1, J. J. Teuteberg4, F. D. Pagani5, A. C. Gaffey6, P. Atluri7, E. Y. Birati8, S. Myers9, D. Naftel9, G. Oliveira10, K. E. Simpson11, R. W. Yeh1, J. K. Kirklin12, R. L. Kormos13, J. Rame8. 1 _Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA,_ 2 _Mid America Heart Institute, St. Luke's Hospital, Kansas City, MO,_ 3 _Division of Cardiovascular Medicine, Tufts Medical Center, Boston, MA,_ 4 _Division of Cardiovascular Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA,_ 5 _Division of Cardiovascular Surgery, University of Michigan, Ann Arbor, MI,_ 6 _Division of Cardiovascular Surgery, Hospital of the University of Pennyslvania, Philadelphia, PA,_ 7 _Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA,_ 8 _Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA,_ 9 _INTERMACS, University of Alabama at Birmingham, Birmingham, AL,_ 10 _Division of Cardiovascular Medicine, University Hospitals Case Medical Center, Cleveland, OH,_ 11 _Division of Pediatric Cardiology, St. Louis Children's Hospital, St. Louis, MO,_ 12 _Division of Cardiovascular Surgery, University of Alabama at Birmingham, Birmingham, AL,_ 13 _Division of Cardiovascular Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA_

**4:45 PM** ( **356)** The Incidence of Early and Late Clinical Right Heart Failure and the Impact on Survival After Continuous Flow Mechanical Support: Insights from the New INTERMACS Definition of Right Heart Failure; __ J. J. Teuteberg1, G. Studdard2, F. Pagani3, M. Kiernan4, G. Oliveria5, E. Rame6, P. Alturi6, A. Gaffey6, E. W. Grandin7, J. Kirlin2, S. Myers2, C. Collum2, R. L. Kormos1. 1 _University of Pittsburgh, Pittsburgh, PA,_ 2 _University of Alabama, Birmingham, Birmingham, AL,_ 3 _University of Michigan, Ann Arbor, MI,_ 4 _Tufts Medical Center, Boston, MA,_ 5 _Case Western, Cleveland, OH,_ 6 _University of Pennsylvania, Philadelphia, PA,_ 7 _Beth Isreal Deaconess, Boston, MA_

**5:00 PM** ( **357)** Normalization of Decoupling Between Diastolic Pulmonary Artery Pressure and Pulmonary Capillary Wedge Pressure in Response to Speed Change Predicts Better Outcome in Patients with Left Ventricular Assist Devices; __ T. Imamura1, G. Sayer1, S. Adatya1, G. Kim1, J. Raikhelkar1, T. Ota1, T. Song1, C. Juricek1, V. Kagan1, D. Rodgers1, V. Jeevanandam1, D. Burkhoff2, N. Uriel1. 1 _University of Chicago, Chicago, IL,_ 2 _University of Columbia, New York, NY_

**5:15 PM** ( **358)** Effect of Transplant Rates on Benefit of Left Ventricular Assist Device versus Inotrope Support; __ J. C. Robertson1, K. D. Aarsonson2, A. Basu1, L. Kessler1, C. Mahr3, N. A. Mokadam4, T. Dardas3. 1 _Health Services, University of Washington, Seattle, WA,_ 2 _Internal Medicine, University of Michigan, Ann Arbor, MI,_ 3 _Medicine, University of Washington, Seattle, WA,_ 4 _Surgery, University of Washington, Seattle, WA_

4:00 PM - 5:30 PM

## ORAL SESSION 36: CAV: New Insights to an Old Problem

Location:

Grand Hall B

Target Audience:

HTX, BSTR, PATH, PHARM

**Chairs:**

Randall C. Starling, MD, MPH, and Marco Masetti, MD

**4:00 PM** ( **359)** Sirolimus-Based Immunosuppression Mitigates Progression of Cardiac Allograft Vasculopathy and Improves Cardiac Outcomes After Heart Transplantation: A Single Center 15-Year Follow-Up Study; __ R. Asleh, A. Briasoulis, J. Tilford, W. Choi, N. L. Pereira, B. S. Edwards, A. L. Clavell, L. D. Joyce, J. M. Stulak, S. Maltais, D. L. Joyce, R. C. Daly, A. Lerman, S. S. Kushwaha. _Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN_

**4:15 PM** ( **360)** Early Aspirin Initiation Following Heart Transplantation Decreases the Risk of Allograft Vasculopathy During Long-Term Follow-Up; __ Y. Peled1, J. Lavee1, E. Raichlin2, M. Katz1, Y. Shemesh1, Y. Kassif1, E. Asher1, D. Elian1, Y. Har-Zahav1, N. Shlomo1, I. Goldenberg1, D. Freimark1, R. Klempfner1. 1 _Sheba Medical Center and Tel Aviv University, Tel Aviv, Israel,_ 2 _University of Nebraska Medical Center, Omaha, NE_

**4:30 PM** ( **361)** Atheroprotective Effect of IgM Anti-Phosphorylcholine Natural Antibodies in Heart Transplant Patients; __ C. A. Labarrere1, J. W. Hardin2, B. R. Jaeger3, D. L. Bhatt4, G. S. Kassab1. 1 _California Medical Innovations Institute, San Diego, CA,_ 2 _Epidemiology and Biostatistics, University of South Carolina, Columbia, SC,_ 3 _Medical Care Center, Laboratory Dr. Stein and Colleagues, Mönchengladbach, Germany,_ 4 _Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, MA_

**4:45 PM** ( **362)** IgM Anti-Phosphorylcholine, Inflammation and Thrombosis: Effects on Heart Transplant Outcomes; __ C. A. Labarrere1, J. W. Hardin2, B. R. Jaeger3, D. L. Bhatt4, G. S. Kassab1. 1 _California Medical Innovations Institute, San Diego, CA,_ 2 _Epidemiology and Biostatistics, University of South Carolina, Columbia, SC,_ 3 _Medical Care Center, Laboratory Dr. Stein and Colleagues, Mönchengladbach, Germany,_ 4 _Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, MA_

**5:00 PM** ( **363)** Early Changes in the Coronary Microstructure After Heart Transplantation: A Prospective Optical Coherence Tomography Study; __ T. S. Clemmensen1, N. R. Holm1, H. Eiskjær1, B. B. Løgstrup1, J. Dijkstra2, C. J. Terkelsen1, M. Maeng1, E. H. Christiansen1, S. H. Poulsen1. 1 _Department of Cardiology, Aarhus University Hospital, Skejby, Denmark, Aarhus N, Denmark,_ 2 _Division of Image Processing, Leiden University Medical Centre, Leiden, Netherlands_

**5:15 PM** ( **364)** Markers of Intermediate-Term Risk After Heart Transplant - Results of the CTOT-18 Study; __ J. Stehlik1, B. Armstrong2, D. A. Baran3, A. Chandraker4, N. D. Bridges5, T. DeMarco6, E. Feller7, M. Givertz4, R. Gordon8, P. S. Heeger9, A. Heroux10, J. Hunt11, D. N. Ikle2, A. G. Kfoury12, J. C. Madsen13, Y. R. Morrison5, S. P. Pinney14, R. C. Starling15, .. for CTOT-18 Investigators1. 1 _University of Utah School of Medicine, Salt Lake City, UT,_ 2 _Rho Federal Systems Division, Chapel Hill, NC,_ 3 _Newark Beth Israel Medical Center, Newark, NJ,_ 4 _Brigham & Women's Hospital, Boston, MA, _5 _DAIT, NIAID, NIH, Bethesda, MD,_ 6 _UCSF, San Franciso, CA,_ 7 _University of Maryland, Baltimore, MD,_ 8 _Northwestern University, Chicago, IL,_ 9 _Mount Sinai School of Medicine, New York, NY,_ 10 _Loyola University School of Medicine, Maywood, IL,_ 11 _Medical City Dallas Hospital, Dallas, TX,_ 12 _Intermountain Medical Center, Salt Lake City, UT,_ 13 _Massachusetts General Hospital, Boston, MA,_ 14 _Mount Sinai School of Medicine, Salt Lake City, UT,_ 15 _The Cleveland Clinic Foundation, Cleveland, OH_

4:00 PM - 5:30 PM

## ORAL SESSION 37: Impact of Donor Characteristics on Lung Transplant Outcomes

Location:

Grand Hall C

Target Audience:

LTX, BSTR, EEP, MCS, NHSAH

**Chairs:**

Arne Neyrinck, MD, PhD, and Cassie C Kennedy, MD

( **365)** WITHDRAWN

**4:00 PM** ( **409)** Making a Case for EPLET Matching...Eplet Matching Is Associated with Improved Baseline Spirometry and Reduced Risk of CLAD Following Lung Transplantation; __ M. Paraskeva1, D. C. Walton2, S. J. Hiho2, J. Fuller3, L. S. Cantwell2, G. P. Westall1, G. I. Snell1. 1 _Lung Transplant Service, Alfred Hospital, Melbourne, Australia,_ 2 _Victorian Transplantation and Immunogenetics Service, Australian Red Cross Blood Service, Melbourne, Australia,_ 3 _Monash University, Melbourne, Australia_

**4:15 PM** ( **366)** 10 Years Experience with Maastricht Category III Donation After Circulatory Death (DCD) in Lung Transplantation (LTx) - Analysis of Early and Long-Term Results in Large Single-Centre Cohort; __ B. Zych1, D. Garcia-Saez1, O. Ananiadou1, P. N. Mohite1, L. Fazekas1, M. Husain1, B. Schmack1, F. De Robertis1, A. F. Popov1, T. Bahrami1, N. Marczin2, A. Reed1, M. Carby1, A. R. Simon1. 1 _Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Harefield Hospital. Royal Brompton and Harefield NHS Foundation Trust, Harefield, United Kingdom,_ 2 _Department of Anaesthesia and Intensive Care, Harefield Hospital. Royal Brompton and Harefield NHS Foundation Trust, Harefield, United Kingdom_

**4:30 PM** ( **367)** Extended Donation After Circulatory Death (DCD) Cat 3 Lung Donor Agonal and Post-Mortem Warm Ischemic Times (WIT) Do Not Affect Early Mortality; __ B. Levvey1, L. Edwards2, A. Robinson2, S. Keshavjee3, M. Erasmus4, A. Glanville5, P. Hopkins6, M. Musk7, A. Patterson8, M. Hertz9, F. D'Ovidio10, K. McCurry11, P. Camp12, B. Carrico2, J. Stehlik13, D. Van Raemdonck14, G. Snell1. 1 _Alfred Hospital, Melbourne, Australia,_ 2 _UNOS, Richmond, VA,_ 3 _Toronto General Hospital, Toronto, ON, Canada,_ 4 _Universitair Medisch Centrum Groningen, Groningen, Netherlands,_ 5 _St Vincent's Hospital, Sydney, Australia,_ 6 _Prince Charles Hospital, Brisbane, Australia,_ 7 _Lung Transplant Program, Fiona Stanley Hospital, Perth, Australia,_ 8 _Barnes-Jewish Hospital, St Louis, MO,_ 9 _Fairview Medical Centre-University of Minnesota, Minneapolis, MN,_ 10 _Columbia Presbyterian Medical Center, New York, NY,_ 11 _The Cleveland Clinic Foundation, Cleveland, OH,_ 12 _Brigham and Womens Hospital, Boston, MA,_ 13 _University of Utah, Salt Lake City, UT,_ 14 _UZ Gasthuisberg Leuven, Leuven, Belgium_

**4:45 PM** ( **368)** Lessons Learned from the First Clinical Trial to Compare Outcomes of Lungs Transplanted from Uncontrolled Donation After Circulatory Determination of Death Donors (uDCDDs) Assessed by Ex-Vivo Lung Perfusion (EVLP) and CT Scan and Lungs Transplanted from Conventional Donors (CONV); __ T. M. Egan1, J. Blackwell1, B. Haithcock1, J. Long1, K. Birchard2, J. Lobo3, S. Masuodi1, J. Requard III4, C. Thys5. 1 _Surgery, U. North Carolina Sch Med, Chapel Hill, NC,_ 2 _Radiology, U. North Carolina Sch Med, Chapel Hill, NC,_ 3 _Medicine, U. North Carolina Sch Med, Chapel Hill, NC,_ 4 _Lung Banks of America, Chapel Hill, NC,_ 5 _Carolina Donor Services, Durham, NC_

**5:00 PM** ( **369)** An In Situ Donor Derived Panel of Innate Immune Transcripts Predicts Primary Graft Dysfunction in Lung Transplant Recipients; __ T. I. Carter1, Y. Suzuki1, J. Lasky1, C. Schaufler1, B. Lim1, D. Mallem1, C. A. Bermudez1, J. M. Diamond2, J. D. Christie3, X. Yu4, R. Feng4, E. Cantu1. 1 _Division of Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA,_ 2 _Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania, Philadelphia, PA,_ 3 _Pulmonary, Allergy, and Critical Care Division; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA,_ 4 _Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA_

**5:15 PM** ( **370)** Donor-Derived Cell-Free DNA Associates with Rejection in Lung Transplantation Using Clinical-Grade Targeted Next-Generation Sequencing; __ K. K. Khush1, J. F. Beausang1, R. N. Woodward2, D. Lew2, J. Sninsky2, I. De Vlaminck3, C. Strehl4, H. Luikart1, M. Nicolls1, D. Weill5. 1 _Stanford University, Stanford, CA,_ 2 _CareDx, Brisbane, CA,_ 3 _Cornell University, Ithica, NY,_ 4 _Florida International University, Miami, FL,_ 5 _Weill Consulting Group, Palo Alto, CA_

4:00 PM - 5:30 PM

## ORAL SESSION 38: The Nightmare of Primary Cardiac Allograft Dysfunction

Location:

Grand Hall D

Target Audience:

HTX, MCS, PHARM

**Chairs:**

Feras Khaliel, MD, PhD, and Maria G Crespo-Leiro, MD

**4:00 PM** ( **371)** Does the New ISHLT Primary Graft Dysfunction (PGD) Grading Scale in Heart Transplantation Predict Outcome?; __ J. Patel, M. Kittleson, T. Aintablian, R. Levine, M. Curry, A. Hage, D. Geft, D. Chang, L. Czer, D. Ramzy, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**4:15 PM** ( **372)** The Incidence and Outcome of Primary Graft Dysfunction After Adult Heart Transplantation in the United Kingdom; __ S. Avtaar Singh1, N. R. Banner2, S. Rushton3, N. Al-Attar1. 1 _Cardiothoracic Surgery, Golden Jubilee National Hospital, Glasgow, United Kingdom,_ 2 _Golden Jubilee National Hospital, Glasgow, United Kingdom,_ 3 _Statistics, National Health Service Blood and Transplant (NHSBT), Bristol, United Kingdom_

**4:30 PM** ( **373)** Treatment of Primary Graft Dysfunction with Plasmapheresis Improves Outcome; __ D. H. Chang, M. Kittleson, J. Patel, T. Aintablian, R. Levine, D. Geft, E. Kransdorf, L. Czer, A. Trento, F. Esmailian, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**4:45 PM** ( **374)** Risk of Early Graft Failure Following Heart Transplantation with Durable Continuous Flow vs. Pulsatile Flow Mechanical Circulatory Support; __ K. J. Clerkin1, D. M. Mancini2, J. Stehlik3, M. A. Clark4, L. B. Edwards4, L. H. Lund5. 1 _Cardiology, Columbia University Medical Center, New York, NY,_ 2 _Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY,_ 3 _Cardiology, University of Utah School of Medicine, Salt Lake City, UT,_ 4 _United Network for Organ Sharing, Richmond, VA,_ 5 _Karolinska Institutet (Department of Medicine) and Karolinska University Hospital (Department of Cardiology), Stockholm, Sweden_

**5:00 PM** ( **375)** Donor Predicted Heart Mass Is Superior to Total Body Weight in Predicting Primary Graft Dysfunction in Undersized Donors; __ T. A. Gong, G. Gonzalez-Stawinski, S. M. Joseph, P. P. Kale, J. C. MacHannaford, A. Rafael, G. Saracino, S. A. Hall, B. Lima. _Advanced Heart Failure and Transplant, Baylor University Medical Center, Dallas, TX_

**5:15 PM** ( **376)** Assessing Risk of Primary Graft Dysfunction in Heart Transplantation (HT); __ S. Shah1, D. Cruz2, M. Deng2, A. Ardehali2, E. C. DePasquale2. 1 _David Geffen School of Medicine, Los Angeles, CA,_ 2 _UCLA Department of Cardiology, Los Angeles, CA_

4:00 PM - 5:30 PM

## ORAL SESSION 39: Early Career Scientist Award in Transplantation Finalist Presentations

Location:

Seaport F-H

Target Audience:

BSTR, HTX, ID, LTX, PATH, PEDS, PHARM

**Chairs:**

Sonja Schrepfer, MD, PhD, and Edward Cantu, MD

**4:00 PM** ( **377)** Transplanting the Human Respiratory Virome; __ A. B. Mitchell1, B. Mourad1, M. A. Malouf2, M. Benzimra2, L. C. Morgan3, B. G. Oliver1, A. R. Glanville4. 1 _Molecular Biology, University of Technology, Sydney, Australia,_ 2 _Lung Transplant Unit, St Vincent's Hospital, Sydney, Australia,_ 3 _Thoracic Medicine, Concord Clinical School, University of Sydney, Sydney, Australia,_ 4 _Thoracic Medicine, St Vincent's Hospital, Sydney, Australia_

**4:15 PM** ( **378)** Differential Modulation of the IL-17A Pathway in Restrictive Allograft Syndrome (RAS) versus Bronchiolitis Obliterans Syndrome (BOS); __ A. Tigert1, T. Saito2, L. Levy1, G. Zehong1, K. Boonstra1, S. Keshavjee1, S. Juvet1, T. Martinu1. 1 _Toronto Lung Transplant Program, Toronto General Hospital, Toronto, ON, Canada,_ 2 _Department of Thoracic Surgery, Kansai Medical University, Hirakata, Japan_

**4:30 PM** ( **379)** Splenic Monocytes Promote Neutrophil Extravasation into Lung Grafts via a TLR9-IL1β-Dependent Pathway; __ H. Hsiao1, T. Takahashi1, Y. Liu1, D. Scozzi1, W. Li1, A. S. Krupnick2, A. E. Gelman3, D. Kreisel1. 1 _Surgery, Washington University in Saint Louis, Saint Louis, MO,_ 2 _Surgery, University of Virginia, Charlottesville, VA,_ 3 _Pathology and Immunology, Washington University in Saint Louis, Saint Louis, MO_

**4:45 PM** ( **380)** Validation of microRNA Profiling in Different Types of Rejection Previously Identified with NGS Technology in Formalin Fixed EMBs; __ A. Di Francesco1, M. Fedrigo2, F. De Pascale3, C. Castellani2, G. Feltrin2, G. Toscano2, A. Fraiese2, E. Benazzi4, A. Nocco4, G. Thiene2, M. Valente2, G. Valle3, G. Gerosa2, A. Angelini2. 1 _University of Padova, Padova, Italy,_ 2 _Cardiac Thoracic and Vascular Sciences, University of Padova, Padova, Italy,_ 3 _CRIBI Biotechnology Centre, University of Padova, Padova, Italy,_ 4 _Organ and Tissue Transplantation Immunology, Fondazione IRCSS Cà Granda Ospedale Maggiore Policlinico, Milano, Italy_

**5:00 PM** ( **381)** Molecular Profiling of Endomyocardial Biopsies and Clinical Phenotype of Graft Dysfunction: Taking Rejection Diagnosis Beyond Pathological Findings; __ L. Borgese1, A. Gaudenzi1, V. Agostini2, M. Masetti1, B. Corti2, J. Reeve3, F. Grigioni1, O. Leone2, P. Halloran3, L. Potena1. 1 _Heart and Lung Transplant Program, University of Bologna, Bologna, Italy,_ 2 _Pathology, University of Bologna, Bologna, Italy,_ 3 _ATAGC, University of Alberta, Edmonton, AB, Canada_

4:00 PM - 5:30 PM

## ORAL SESSION 40: Drugs, Bleeding and Enzymes ... Oh My!

Location:

Coronado A-C

Target Audience:

PHARM, HTX, ID, LTX, MCS, NHSAH

**Chairs:**

Walter Uber, PharmD, and Rochelle M Gellatly, PharmD

**4:00 PM** ( **382)** Impact of Angiotensin II Inhibitors on the Incidence of Gastrointestinal Bleeds After Left Ventricular Assist Device Placement; __ M. Converse, M. Sobhanian, A. Mardis, D. Taber, W. Uber, H. Meadows, B. Houston, N. Patel, A. Vanbakel. _Pharmacy, Medical University of South Carolina, Charleston, SC_

**4:15 PM** ( **383)** Evaluation of Prothrombin Complex Concentrate in Warfarin Reversal Prior to Heart Transplantation in Patients with Durable Mechanical Circulatory Support; __ C. I. Konopka1, E. T. Horn1, S. Murali2, R. L. Benza2, R. J. Moraca3, S. H. Bailey3. 1 _Department of Pharmacy, Allegheny General Hospital, Pittsburgh, PA,_ 2 _Division of Cardiovascular Medicine, Allegheny General Hospital, Pittsburgh, PA,_ 3 _Division of Cardiothoracic Surgery, Allegheny General Hospital, Pittsburgh, PA_

**4:30 PM** ( **384)** Stimulated T-Cell Interferon Gamma Responses as a Biomarker of Immune Function; __ S. Yogakanthi1, A. Y. Peleg2, E. Paul3, Y. Cristiano1, G. Snell1, G. Westall1. 1 _Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital & Monash University, Melbourne, Australia, _2 _Department of Infectious Diseases, Alfred Hospital & Monash University, Melbourne, Australia, _3 _Department of Epidemiology & Preventive Medicine, Monash University, Melbourne, Australia_

**4:45 PM** ( **385)** Impact of CYP3A5, CYP3A4, and ABCB1 Genotypes on Lung Transplant Recipient Early Clinical Outcomes; __ D. R. Calabrese1, R. Boettger2, K. Dewey2, C. Hui2, D. Torgerson1, H. Faust3, R. Rajalingam4, S. Hays1, J. Singer1, R. Shah1, L. Leard1, J. Kukreja4, J. Golden1, J. Greenland5. 1 _Department of Medicine, University of California San Francisco, San Francisco, CA,_ 2 _Department of Clinical Pharmacy, University of California San Francisco, San Francisco, CA,_ 3 _Department of Medicine, University of Pennsylvania Health System, Philadelphia, PA,_ 4 _Department of Sugery, University of California San Francisco, San Francisco, CA,_ 5 _Medical Service, Veterans Affairs Medical Center, San Francisco, CA_

**5:00 PM** ( **386)** Tacrolimus Dosing Requirements Are Reduced in Heart Transplant Recipients with Severe Primary Graft Dysfunction on ECMO Support; __ N. Breslin, D. Salerno, N. Jandovitz, D. Tsapepas, S. Restaino, F. Latif, P. Colombo, M. Farr, D. L. Jennings. _New York Presbyterian Columbia Irving Medical Center, New York, NY_

**5:15 PM** ( **387)** Relationship Between Patient-Perceived Treatment Burden and Medication Adherence in Heart Transplant Recipients; __ K. M. Deininger1, J. D. Hirsch2, S. A. Graveline2, A. A. Feist2, S. M. Smith3, J. A. Reich1, J. LaFleur4, A. V. Ambardekar1, J. Lindenfeld5, C. L. Aquilante1. 1 _University of Colorado, Aurora, CO,_ 2 _University of California San Diego, La Jolla, CA,_ 3 _University of Florida, Gainesville, FL,_ 4 _University of Utah, Salt Lake City, UT,_ 5 _Vanderbilt University, Nashville, TN_

5:45 PM - 6:45 PM

## MINI ORAL SESSION 13: Controversies in Heart Transplantation

Location:

Grand Hall A

Target Audience:

## HTX, MCS

**Chairs:**

William Stansfield, MD, and Susan Woodley Restaino, MD

**5:45 PM** ( **388)** Cardiac Transplantation in Patients Supported with Extracorporeal Membrane Oxygenation (ECMO): Early and Mid-Term Results; __ P. Noly1, E. Flecher2, M. Hebert1, M. Mauduit2, Y. Lamarche1, J. Verhoye2, M. Carrier1. 1 _Cardiac Surgery, Montreal Heart Institute, Montreal, QC, Canada,_ 2 _Cardiac Surgery, Rennes Hospital, Rennes, France_

**5:50 PM** ( **389)** Extracorporeal Membrane Oxygenation (ECMO) as a Bridge to Heart Transplantation: Impact on Post Transplantation Outcomes; __ A. C. Gaffey1, C. W. Chen1, J. J. Chung1, L. R. Goldberg2, C. A. Bermudez1, M. A. Acker1, P. Atluri1. 1 _Department of Surgery, University of Pennsylvania, Philadelphia, PA,_ 2 _Department of Medicine, University of Pennsylvania, Philadelphia, PA_

**5:55 PM** ( **390)** Trends in Combined Heart-Kidney Transplantation and Impact on Patient Survival; __ D. Vucicevic1, L. Honoris1, A. Salimbangon1, A. Chang1, E. Moreno1, M. Moore1, L. Sweet1, S. Shah1, A. Iyengar1, K. Pandya2, A. Ardehali3, M. Deng1, E. DePasquale1. 1 _Department of Cardiology, UCLA, Los Angeles, CA,_ 2 _Department of Cardiology, UC Davis, Davis, CA,_ 3 _Department of Cardiothoracic Surgery, UCLA, Los Angeles, CA_

**6:00 PM** ( **391)** Simultaneous Heart-Kidney Transplantation Is Superior to Sequential Heart-Kidney Transplantation in Renal Failure Heart Transplant Candidates; __ M. S. Mulvihill1, B. A. Yerokun1, P. Patel2, J. G. Rogers2, C. A. Milano1, C. B. Patel2, M. G. Hartwig1. 1 _Department of Surgery, Duke University, Durham, NC,_ 2 _Department of Medicine, Duke University, Durham, NC_

**6:05 PM** ( **392)** Attenuation of Cardiac Allograft Vasculopathy in Dual Organ Transplantation; __ K. J. Clerkin1, S. W. Restaino1, F. Latif1, M. A. Farr1, E. Zorn2, D. M. Mancini3, K. Takeda4, H. Takayama4, Y. Naka4, P. C. Colombo1, V. K. Topkara1. 1 _Cardiology, Columbia University Medical Center, New York, NY,_ 2 _Immunology, Columbia University Medical Center, New York, NY,_ 3 _Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY,_ 4 _Cardiac Surgery, Columbia University Medical Center, New York, NY_

**6:10 PM** ( **393)** Impact of Cardiac Allograft Vasculopathy and Treated Rejection on Sudden Cardiac Death in Patients Receiving a Cardiac Transplant. An Analysis of the ISHLT Registry Data; __ A. C. Alba1, C. S. Fan2, C. Manlhiot2, A. I. Dipchand3, J. Stehlik4, H. J. Ross1. 1 _Toronto General Hospital - University Health Network, Toronto, ON, Canada,_ 2 _The Hospital for Sick Children - University of Toronto, Toronto, ON, Canada,_ 3 _Heart Transplant Program, The Hospital for Sick Children - University of Toronto, Toronto, ON, Canada,_ 4 _University of Utah School of Medicine, Salt Lake City, UT_

**6:15 PM** ( **394)** Positron Emission Tomography Is Associated with the Presence of Cardiac Allograft Vasculopathy on Coronary Angiography; __ M. C. Konerman1, J. J. Lazarus1, R. L. Weinberg1, M. Ghannam1, A. Saleh1, H. Yun1, V. M. Moles1, S. L. Hummel1, R. V. Shah2, J. R. Corbett1, K. D. Aaronson1, M. M. Colvin1, T. M. Koelling1, V. L. Murthy1. 1 _University of Michigan, Ann Arbor, MI,_ 2 _Beth Israel Deaconess Medical Center, Boston, MA_

**6:20 PM** ( **395)** Highly Automated Analysis of Intimal and Medial Thickness in Heart-Transplant Coronary OCT Facilitates Longitudinal Studies of CAV Progression; __ Z. Chen1, A. Wahle1, Z. Guo1, H. Zhang1, V. Karmazin2, A. Tomasek3, H. Bedanova3, J. J. Lopez4, T. Kovarnik5, M. Pazdernik2, M. Sonka1. 1 _University of Iowa, Iowa City, IA,_ 2 _IKEM, Prague, Czech Republic,_ 3 _Cardiovascular and Transplantation Surgery, Brno, Czech Republic,_ 4 _Loyola University, Chicago, IL,_ 5 _Charles University, Prague, Czech Republic_

**6:25 PM** ( **396)** Strategies to Reduce Tricuspid Regurgitation After Heart Transplant; __ K. Carl1, A. M. Borkon1, S. Aggarwal1, K. Allen1, R. Davis1, A. Pak1, E. Thompson1, J. Wang2, A. Kao3, A. Magalski3, S. Lawhorn3, T. Khumari3, B. Austin3. 1 _Cardiovascular Surgery, Mid America Heart Institute of Saint Luke's Hospital, Kansas City, MO,_ 2 _Biostatistics, Mid America Heart Institute of Saint Luke's Hospital, Kansas City, MO,_ 3 _Cardiology, Mid America Heart Institute of Saint Luke's Hospital, Kansas City, MO_

**6:30 PM** ( **397)** Predictors of Clinical Outcome and Subsequent Target Lesion Revascularization After Percutaneous Coronary Procedures with Drug Eluting Stents and Everolimus Eluting Bioresorbable Scaffolds for Cardiac Allograft Vasculopathy; __ F. M. Turazza, V. Vaccaro, I. M. Bossi, M. D'Anna, G. Piccalò, G. L. Pedrazzini, G. Masciocco, G. Foti, P. Colombo, E. Perna, E. Ammirati, M. Frigerio. _"A De Gasperis" Dept., Ospedale Niguarda Ca' Granda, Milano, Italy_

**6:35 PM** ( **398)** MRI Findings in Late Cardiac Allograft Failure; __ M. Hyden, E. Raichlin. _Cardiology, UNMC, Omaha, NE_

**6:40 PM** ( **399)** A Comparison of Two-Dimensional Echocardiography Parameters with Cardiac Magnetic Resonance Imaging in the Assessment of Right Ventricular Function Post Orthotopic Heart Transplantation; __ M. Hyden, R. K. Anchan, R. High, S. Saxena. _Department of Internal Medicine, Nebraska Medicine, Omaha, NE_

5:45 PM - 6:45 PM

## MINI ORAL SESSION 14: Recipient Risk Factors Affecting Outcome after Lung Transplantation

Location:

Grand Hall B

Target Audience:

LTX, BSTR, EEP, ID, NHSAH, PATH, PHARM

**Chairs:**

Peter M Hopkins, FRACP, and Cynthia J. Gries, MD, MSc

**5:45 PM** ( **400)** How Old Is Old to Have a Lung Transplantation - Results from a Single Center; __ Y. Toyoda1, J. Gomez-Abraham1, S. Keshavamurthy1, T. Yoshizumi1, H. Zhao2, F. Cordova3, S. Kartik1, A. J. Mamary3, G. Criner1, A. Kashem1. 1 _Cardiovascular Surgery, Temple University, Philadelphia, PA,_ 2 _Department of Clinical Science and Statistics, Temple University, Philadelphia, PA,_ 3 _Thoracic and Pulmonary Medicine, Temple University, Philadelphia, PA_

**5:50 PM** ( **401)** Preexisting Coronary Artery Disease Is Associated with Higher Morbidity in Patients Undergoing Lung Transplantation; __ S. Biswas Roy1, M. Olson2, D. Harned1, P. Kang3, R. Panchanathan4, A. Hashimi1, J. Huang1, H. Abdelrazek1, V. Patel1, A. Omar1, R. M. Bremner1, M. A. Smith1, R. Walia1, A. V. Kalya1. 1 _Norton Thoracic Institute, St. Joseph's Hospital & Medical Center, Phoenix, AZ, _2 _Grand Canyon University, Phoenix, AZ,_ 3 _University of Arizona College of Public Health, Phoenix, AZ,_ 4 _University of Arizona Medical School, Phoenix, AZ_

**5:55 PM** ( **402)** Prognostic Factors in Lung Transplantation After Hematopoietic Stem Cell Transplantation; __ T. F. Chen-Yoshikawa1, S. Sugimoto2, T. Shiraishi3, M. Minami4, Y. Matsuda5, M. Chida6, S. Maeda6, A. Aoyama1, Y. Okada5, M. Okumura4, A. Iwasaki3, S. Miyoshi2, T. Oto7, H. Date1. 1 _Thoracic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan,_ 2 _General Thoracic Surgery, Okayama University Hospital, Okayama, Japan,_ 3 _Thoracic Surgery, Fukuoka University Hospital, Fukuoka, Japan,_ 4 _General Thoracic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan,_ 5 _Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan,_ 6 _General Thoracic Surgery, Graduate School of Medicine, Dokkyo Medical University, Mibu, Japan,_ 7 _Organ Transplant Center, Okayama UniversityHospital, Okayama, Japan_

**6:00 PM** ( **403)** Lung Volumes Pre and Post Transplant: The Frustrum Model; __ S. Park, W. Ring, M. A. Wait. _Thoracic & Cardiovascular Surgery, UT Southwestern Medical Center, Dallas, TX_

**6:05 PM** ( **404)** Impact of Acute Respiratory Syncytial Virus Infection on the Lung Function of Lung Transplant Recipients: What Happens?; __ H. Lafoeste1, C. Picard1, L. Beaumont1, E. Farfour2, S. De Miranda1, B. Douvry1, A. Hamid1, N. Carlier1, D. Grenet1, F. Parquin3, E. Sage3, A. Roux1. 1 _Respiratory Medicine, Foch Hospital, Suresnes, France,_ 2 _Microbiology Department, Foch Hospital, Suresnes, France,_ 3 _Thoracic Surgery, Foch Hospital, Suresnes, France_

**6:10 PM** ( **405)** Post-Lung Transplant Esophageal Impedance/pH Studies Do Not Predict Onset of RAS or BOS Phenotypes; __ O. M. Crespin1, T. Martinu2, J. Tikkanen2, W. Klement2, A. Okrainec1, L. Liu3, M. Cypel2, S. Keshavjee2, G. E. Darling4, J. C. Yeung2. 1 _Division of General Surgery, University of Toronto, Toronto, ON, Canada,_ 2 _Toronto Lung Transplant Program, University of Toronto, Toronto, ON, Canada,_ 3 _Division of Gastroenterology, University of Toronto, Toronto, ON, Canada,_ 4 _Division of Thoracic Surgery, University of Toronto, Toronto, ON, Canada_

**6:15 PM** ( **406)** Prevalence and Predictors of Severe Bronchial Complications Following Lung Transplantation; __ K. Narm, S. Lee, J. Suh, J. Lee, A. Kim, H. Paik. _Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea, Republic of_

**6:20 PM** ( **407)** Repertoire Analysis of De Novo Non-HLA Antibodies Associated with Chronic Lung Allograft Rejection Following Human Lung Transplantation; __ D. Nayak, R. Walia, R. Bremner, M. Smith, T. Mohanakumar. _St. Joseph's Hospital & Medical Center, Phoenix, AZ_

**6:25 PM** ( **408)** Early Elevation of Anti-HLA Immunoglobulin M Level Is Associated with Subsequent Lung Transplant Rejection and Worse Outcomes; __ K. Miyahara, K. Miyoshi, T. Kurosaki, S. Otani, S. Sugimoto, M. Yamane, T. Oto. _Department of Thoracic Surgery, Organ Transplant Center, Okayama University Hospital, Okayama-shi,Okayama prefecture, Japan_

**6:30 PM** ( **409)** MOVED TO ORAL SESSION 37

**6:35 PM** ( **410)** The Histomorphological Spectrum of Restrictive Chronic Lung Allograft Dysfunction (rCLAD): Implications for Its Etiopathogenesis and Evidence for Prognostic Patterns of Fibrosis; __ J. H. von der Thüsen1, E. Vandermeulen2, R. Vos2, B. Weynand3, E. Verbeken3, S. E. Verleden2. 1 _Department of Pathology, Erasmus MC, Rotterdam, Netherlands,_ 2 _Lung Transplant Unit, Department of Clinical and Experimental Medicine, KU Leuven, Leuven, Belgium,_ 3 _Department of Pathology, UZ Gasthuisberg, Leuven, Belgium_

**6:40 PM** ( **411)** Can Lymphocytes Subtypes in Broncoalveolar Lavage Predict the Response to the Extracorporeal Photopheresis?; __ M. Aguilar Perez1, R. Castejón Diaz2, S. Aguado Ibañez1, R. Laporta Hernandez1, M. T. Lazaro Carrasco De La Fuente1, P. Minguez Clemente1, J. L. Bueno Cabrera1, P. Ussetti Gil1. 1 _Pulmonary Department, Universitary Puerta de Hierro Majadahonda Hospital, Madrid, Spain,_ 2 _Internal Medicine Department, Universitary Puerta de Hierro Majadahonda Hospital, Madrid, Spain_

5:45 PM - 6:45 PM

## MINI ORAL SESSION 15: Pediatric Heart Failure, MCS, and Peri-Transplant Issues

Location:

Grand Hall C

Target Audience:

PEDS, HF, HTX, MCS

**Chairs:**

Ranny Goldwasser, MD, and Janet N Scheel, MD

**5:45 PM** ( **412)** Risk Factors for Death or Heart Transplant for Patients with Right Ventricular Dysfunction After the Norwood Procedure: A Secondary Analysis of the Single Ventricle Reconstruction Trial; __ E. Jean-St-Michel1, J. M. Meza2, J. Coles3, J. Maguire1, B. W. McCrindle1. 1 _Paediatrics, Hospital for Sick Children, Toronto, ON, Canada,_ 2 _Congenital Heart Surgeons' Society Data Center, Hospital for Sick Children, Toronto, ON, Canada,_ 3 _Surgery, Hospital for Sick Children, Toronto, ON, Canada_

**5:50 PM** ( **413)** Weaning Evaluation Protocol for Pediatric Patients After Assist Device Implantation; __ S. Schubert, J. Nordmeyer, B. Peters, F. Berger, S. Weber, K. R. Schmitt, O. Miera. _Congenital Heart Disease, Deutsches Herzzentrum Berlin and DZHK-Partner Site Berlin, Berlin, Germany_

**5:55 PM** ( **414)** Weaning from Ventricular Assist Devices in Children: Predictors for Recovery and Long-Term Follow Up; __ O. Miera1, M. Germann1, M. Cho2, M. Yigitbasi1, M. Musci2, J. Photiadis2, F. Berger1, K. R. Schmitt1. 1 _Congenital Heart Disease / Pediatric Cardiology, Deutsches Herzzentrum Berlin, Berlin, Germany,_ 2 _Surgery for Congenital Heart Disease / Pediatric Cardiac Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany_

**6:00 PM** ( **415)** Mechanical Circulatory Support (MCS) in Infants with Congenital Heart Disease Listed for Heart Transplant- A PHTS Multicenter Experience; __ J. Conway1, E. Pruitt2, R. Spicer3, D. Gupta4, M. McCulloch5, A. Asante-Korang6, D. T. Eulrich7, J. Kirlin2, E. Pahl8. 1 _Stollery Children's Hospital, Edmonton, AB, Canada,_ 2 _University of Alabama at Birmingham, Birmingham, AL,_ 3 _The Children's Hospital and Medical Center, Omaha, NE,_ 4 _University of Florida, Shands Hospital, Gainesville, FL,_ 5 _Nemours Cardiac Center, Wilmington, DE,_ 6 _John Hopkins All Children's Institute, St. Petersburg, FL,_ 7 _University of Alberta, Edmonton, AB, Canada,_ 8 _Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, IL_

**6:05 PM** ( **416)** Post-Transplant Outcomes of Patients Supported with the Berlin Heart EXCOR as a Bridge to Transplantation: A Multi-Institutional Study; __ A. Jeewa1, M. Imamura2, C. Canter3, R. Niebler4, C. VanderPluym5, D. Rosenthal6, J. K. Kirklin7, M. Tresler7, M. McMullan8, V. Morell9, M. Turrentine10, R. Ameduri11, K. Nguyen12, K. Kanter13, J. Conway14, R. Gajarski15, C. D. Fraser Jr16. 1 _The Hospital for Sick Children, Toronto, ON, Canada,_ 2 _Arkansas Children's Hospital, Little Rock, AR,_ 3 _St. Louis Children's Hospital, St. Louis, MO,_ 4 _Children's Hospital of Wisconsin, Milwaukee, WI,_ 5 _Boston Children's Hospital, Boston, MA, Canada,_ 6 _Lucile Packard Children's Hospital at Stanford, Palo Alto, CA,_ 7 _University of Alabama at Birmingham, Birmingham, AL,_ 8 _Seattle Children's Hospital, Seattle, WA,_ 9 _Children's Hospital of Pittsburgh, Pittsburgh, PA,_ 10 _Riley Hospital for Children, Indianapolis, IN,_ 11 _University of Minnesota, Minneapolis, MN,_ 12 _Mount Sinai Medical Center, New York, NY,_ 13 _Children's Healthcare of Atlanta, Atlanta, GA,_ 14 _The Stollery Children's Hospital, Edmonton, AB, Canada,_ 15 _Nationwide Children's Hospital, Columbus, OH,_ 16 _Texas Children's Hospital, Houston, TX_

**6:10 PM** ( **417)** Development of Miniature, Implantable Pediatric Ventricular Assist Device; __ P. D. Wearden1, T. A. Snyder2, J. R. Stanfield3, P. Coghill3, D. Crompton4, S. E. Olia5, S. Ye6, M. V. Kameneva6, W. R. Wagner6, J. W. Long2. 1 _Nemours Cardiac Center, Nemours Childrens Hospital, Orlando, FL,_ 2 _INTEGRIS Advanced Cardiac Care, INTEGRIS Baptist Medical Center, Oklahoma City, OK,_ 3 _VADovations, Oklahoma City, OK,_ 4 _University of Pittsburgh, Pittsburgh, PA,_ 5 _Bioengineering, University of Pittsburgh, Pittsburgh, PA,_ 6 _McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA_

**6:15 PM** ( **418)** Initial In Vitro Testing of a Pediatric Continuous-Flow Total Artificial Heart; __ K. Fukamachi, D. J. Horvath, J. H. Karimov, G. Sunagawa, N. Byram, B. D. Kuban, S. Gao, R. Dessoffy, N. Moazami. _Cleveland Clinic Foundation, Cleveland, OH_

**6:20 PM** ( **419)** Predictors of Long Ischemic Time in Pediatric Heart Transplantation; __ F. Zafar1, T. Weiss1, I. Wilmot2, T. D. Ryan2, C. Chin2, R. Bryant1, D. L. Morales1. 1 _Cardiothoracic Surgery, Children 's Hospital Med Ctr Texas Children 's Hospital, Cincinnati, OH,_ 2 _Cardiology, Children 's Hospital Med Ctr Texas Children 's Hospital, Cincinnati, OH_

**6:25 PM** ( **420)** Does Distance Matter in Pediatric Heart Transplantation?; __ M. J. Bock1, S. Malerba2, I. D. Lytrivi3. 1 _Pediatric Cardiology, Loma Linda University Children's Hospital, Loma Linda, CA,_ 2 _Icahn School of Medicine at Mount Sinai, New York, NY,_ 3 _Pediatric Cardiology, Icahn School of Medicine at Mount Sinai, New York, NY_

**6:30 PM** ( **421)** The Virtual Heart Transplant - The Next Step in Size Matching for Pediatric Heart Transplantation; __ J. D. Plasencia1, J. R. Ryan2, S. S. Park3, J. J. Nigro3, D. H. Frakes1, S. G. Pophal3, S. D. Zangwill3. 1 _School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ,_ 2 _Cardiac 3D Print Lab, Phoenix Children's Hospital, Phoenix, AZ,_ 3 _Cardiology, Phoenix Children's Hospital, Phoenix, AZ_

**6:35 PM** ( **422)** Systemic Venous Reconstructions During Pediatric Heart Transplantation; __ F. Altin1, B. Alsoufi2, K. Kanter2, S. R. Deshpande3. 1 _Cardiothoracic Surgery, Emory University Children's Healthcare of Atlanta, Atlanta, GA,_ 2 _Cardiothoracic Surgery, Emory University, Atlanta, GA,_ 3 _Pediatric Cardiology, Emory University Children's Healthcare of Atlanta, Atlanta, GA_

**6:40 PM** ( **423)** Transplantation in Adults with Congenital Heart Disease: A Special Exception; __ J. D. Sparks1, C. Alexander1, A. Lenneman2, J. Trivedi3, M. Slaughter3. 1 _Pediatrics, University of Louisville, Louisville, KY,_ 2 _Medicine, University of Louisville, Louisville, KY,_ 3 _Cardiothoracic Surgery, University of Louisville, Louisville, KY_

5:45 PM - 6:45 PM

## MINI ORAL SESSION 16: Assessing and Managing the Failing Right Ventricle

Location:

Grand Hall D

Target Audience:

PH, BSTR, HF, HTX, LTX, PHARM

**Chairs:**

Arezu Z. Aliabadi, MD, and Amresh Raina, MD

**5:45 PM** ( **424)** Switch from Bosentan to Macitentan in Adult Outpatients with Pulmonary Arterial Hypertension: A Real-World Study; __ M. T. Politi1, N. A. Caruso2, J. Lescano2, J. M. Farina1, D. N. Spagnuolo1, R. Ferreyra1, G. R. Bortman3. 1 _Cardiology, Sanatorio de la Trinidad Mitre, Buenos Aires, Argentina,_ 2 _Heart Transplant and Pulmonary Hypertension, Sanatorio de la Trinidad Mitre, Buenos Aires, Argentina,_ 3 _Heart Trasplant and Pulmonary Hypertension, Sanatorio de la Trinidad Mitre, Buenos Aires, Argentina_

**5:50 PM** ( **425)** Impact of TPG on Six Month and One Year Waitlist Mortality During Listing for Heart Transplant; __ A. Guha, A. S. Cruz-Solbes, D. Nguyen, B. Trachtenberg, A. Bhimaraj, E. Graviss, J. D. Estep, M. Park. _Methodist DeBakey Heart Center, Houston Methodist Hospital, Houston, TX_

**5:55 PM** ( **426)** Preoperative Serum Markers of Liver Dysfunction Are Associated with Early Postoperative Mortality in Patients with Pulmonary Hypertension Undergoing Lung Transplantation; __ T. Kato1, L. Donahoe1, H. Oishi1, J. Lopez1, S. Azad1, M. Cypel1, M. de Perrot1, A. Pierre1, K. Yasufuku1, T. Waddell1, J. Granton2, L. G. Singer3, K. Kaga4, Y. Matsui4, S. Keshavjee1. 1 _Thoracic Surgery, Toronto General Hospital, Toronto, ON, Canada,_ 2 _Respirology, University Health Network, Mount Sinai Hospital and Women's College Hospital, Toronto, ON, Canada,_ 3 _Medicine, University of Toronto, Toronto, ON, Canada,_ 4 _Cardiovascular and Thoracic Surgery, Hokkaido University, Sapporo, Japan_

**6:00 PM** ( **427)** Right Ventricular Longitudinal Strain versus Tricuspid Annular Plane Systolic Excursion in Patients with Chronic Thromboembolic Pulmonary Hypertension; __ A. G. Connelly1, P. G. Chiles1, W. R. Auger2, D. G. Blanchard3, T. M. Fernandes2. 1 _Department of Internal Medicine, UC San Diego, San Diego, CA,_ 2 _Division of Pulmonary, Critical Care & Sleep Medicine, UC San Diego, San Diego, CA, _3 _Division of Cardiovascular Medicine, UC San Diego, San Diego, CA_

**6:05 PM** ( **428)** The Nuclear Orphan Receptors NR4A as Therapeutic Target in Pulmonary Arterial Hypertension; __ X. Nie, W. Mao, J. Tan, Y. Dai, J. Chen. _Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China_

**6:10 PM** ( **429)** Right Ventricle on Fire: Interleukin-6 Is Independently Associated with Right Ventricular Function in Pulmonary Arterial Hypertension; __ K. Prins1, L. Rose1, S. L. Archer2, A. Sharma1, M. Pritzker1, T. Thenappan1. 1 _Medicine- Cardiology, University of Minnesota, Minneapolis, MN,_ 2 _Medicine- Cardiology, Queens University, Kinston, ON, Canada_

**6:15 PM** ( **430)** Doppler Echocardiography Provides a Reliable Estimate of Elevated Pulmonary Vascular Resistance in Patients with Advanced Lung and Liver Disease; __ J. Svetlichnaya, M. Manicardi, V. Selby, L. Klein, M. Janmohamed, T. De Marco. _University of California San Francisco, San Francisco, CA_

**6:20 PM** ( **431)** Transendocardial CD34+ Cell Therapy Improves Right Ventricular Function in Dilated Cardiomyopathy Patients; __ S. Frljak1, G. Poglajen1, G. Zemljic1, A. Cerar1, M. Bervar1, R. Okrajsek1, M. Jaklic1, F. Haddad2, B. Vrtovec1. 1 _Advanced Heart Failure and Transplantation Center, UMC Ljubljana, Ljubljana, Slovenia,_ 2 _Stanford Cardiovascular Institute, Stanford, CA_

**6:25 PM** ( **432)** Should We Amplify Cardiac Response Criteria in Patients with Cardiac Light-Chain Amyloidosis Treated with Bortezomib?; __ J. Vázquez, A. Durante, F. Hernández, V. Moñivas Palomero, S. Mingo, I. Sayago, P. García Pavía, L. Alonso-Pulpón, J. Segovia Cubero. _Cardiology, Hospital Puerta de Hierro, Madrid, Spain_

**6:30 PM** ( **433)** Beta Blocker Use in Patients with LVADs Is Associated with Lower proBNP and Is Not Associated with Heart Failure Hospitalizations or an Increase in Adverse Events; __ G. Vaidya, B. C. Salgado, J. Pillarella, C. L. Dunbar-Matos, R. Vijayakrishnan, A. Lenneman, M. S. Slaughter, E. Birks, D. Abramov. _Division of Cardiovascular Medicine, University of Louisville, Louisville, KY_

**6:35 PM** ( **434)** Painting Profiles of Ambulatory Advanced Heart Failure: A Report from the REVIVAL Registry; __ M. M. Kittleson1, P. Shah2, A. Lala3, R. McLean4, S. Pamboukian5, D. Horstmanshof6, J. Thibodeau7, K. Shah8, D. Lanfear9, J. Teuteberg10, W. Taddei-Peters11, S. Khalatbari12, L. Stevenson13, D. Mann14, K. Aaronson12, G. Stewart13. 1 _Cedars Sinai Hrt Insti, Los Angeles, CA,_ 2 _Inova Heart and Vascular Institute, Fairfax, VA,_ 3 _Mount Sinai Hospital, New York, NY,_ 4 _University of Pennsylvania, Philadelphia, PA,_ 5 _University of Alabama at Birmingham, Birminghal, AL,_ 6 _INTEGRIS Baptist Medical Center, Oklahoma City, OK,_ 7 _University of Texas Southwestern Medical Center, Dallas, TX,_ 8 _Virginia Commonwealth University, Richmond, VA,_ 9 _Henry Ford Hospital, Detroit, MI,_ 10 _University of Pittsburgh, Pittsburgh, PA,_ 11 _National Heart, Lung and Blood Institute, Bethesda, MD,_ 12 _University of Michigan, Ann Arbor, MI,_ 13 _Brigham and Women's Hospital, Boston, MA,_ 14 _Washington University School of Medicine, St. Louis, MO_

**6:40 PM** ( **435)** Noninvasive Assessment of Lung Fluid Percentage in Heart Transplant Recipients Using Remote Dielectric Sensing; __ G. Sayer1, T. Imamura1, S. Adatya1, G. H. Kim1, D. Rodgers1, A. Nguyen1, B. Chung1, J. Raikhelkar1, N. Sarswat1, R. Abbo2, D. Burkhoff3, N. Uriel1. 1 _University of Chicago, Chicago, IL,_ 2 _Sensible Medical, Tel Aviv, Israel,_ 3 _Columbia University, New York, NY_

5:45 PM - 6:45 PM

## MINI ORAL SESSION 17: Progress in MCS Outcomes

Location:

Seaport F-H

Target Audience:

MCS, HF, HTX, ID, NHSAH, PHARM

**Chairs:**

Andre Vincentelli, MD, PhD, and Andrae Wasler, MD

**5:45 PM** ( **436)** Inert Gas Rebreathing - A Helpful Tool in LVAD Patient Management; __ N. Reiss1, T. Schmidt1, S. Mommertz1, E. Deniz2, C. Feldmann2, S. Schulte-Eistrup1, D. Willemsen1, J. Schmitto2. 1 _Schuechtermann Clinic Bad Rothenfelde, Bad Rothenfelde, Germany,_ 2 _Hannover Medical School, Hannover, Germany_

**5:50 PM** ( **437)** β-Blockers Use During Support with Continuous-Flow Left Ventricular Assist Device in Patients with and without Right Ventricular Dysfunction; __ M. Yin, A. Pekarek, K. Wittersheim, R. T. Cole, D. Gupta, R. Laskar, A. Smith, D. Vega, A. Morris. _Emory University School of Medicine, Atlanta, GA_

**5:55 PM** ( **438)** Single Center Experience with "Lysis First" as Treatment Strategy of Device Thrombosis in the HeartWare HVAD; __ C. Heim, M. Kondruweit, M. Weyand, R. Tandler. _University of Erlangen Department of Cardiac Surgery, Erlangen, Germany_

**6:00 PM** ( **439)** Concomitant Valve Procedures Are Not Associated with Higher Perioperative Mortality; __ T. Sugiura, C. Kurihara, M. Kawabori, W. E. Cohn, A. B. Civitello, O. H. Frazier, J. A. Morgan. _Texas Heart Institute, Houston, TX_

**6:05 PM** ( **440)** Echocardiographic Predictors of Hemodynamics in Patients Supported with Left Ventricular Assist Devices; __ J. Grinstein1, E. Kruse1, S. Kalantari Tannenbaum1, D. Rodgers1, S. Adatya1, G. Sayer1, G. H. Kim1, N. Sarswat1, J. Raikhelkar1, V. Kagan1, H. Costantini1, D. Burkhoff2, V. Jeevanandam1, R. Lang1, N. Uriel1. 1 _University of Chicago, Chicago, IL,_ 2 _Columbia University, New York, NY_

**6:10 PM** ( **441)** The Impact of Blood Pressure Control on the Development of Left Ventricular Distension with VA-ECMO: A Comparison of Vasodilation vs. Diuresis; __ J. Han1, H. Takayama1, D. Burkhoff2, M. L. Dickstein3. 1 _Division of Cardiothoracic Surgery, Columbia University Medical Center, New York, NY,_ 2 _Division of Cardiology, Columbia University Medical Center, New York, NY,_ 3 _Division of Cardiothoracic Anesthesia, Columbia University Medical Center, New York, NY_

**6:15 PM** ( **442)** Novel Palliative Care Integration Program increases Days Alive and Out of Hospital and Reduces Inpatient Direct Costs Among Left Ventricular Assist Device Patients; __ S. Nakagawa1, J. M. Luna2, V. K. Topkara3, M. Yuzefpolskaya3, D. Vawdrey2, A. R. Garan3, H. Takayama4, K. Takeda4, P. C. Colombo3, Y. Naka4, C. D. Blinderman1. 1 _Adult Palliative Care Services, Department of Medicine, Columbia University Medical Center, New York, NY,_ 2 _Value Institute, NewYork-Presbyterian Hospital, New York, NY,_ 3 _Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY,_ 4 _Division of Cardiothoracic Surgery, Department of Surgery, Columbia University Medical Center, New York, NY_

**6:20 PM** ( **443)** Radically Redesigned Approach to LVAD Adverse Event Management; __ M. Old Crow, S. Jones, N. Chelikani, M. El Banayosy, H. Setiadi, J. Long, D. Horstmanshof, K. Nelson. _Advanced Cardiac Care, INTEGRIS Baptist Medical Center, Oklahoma City, OK_

**6:25 PM** ( **444)** The Anemic Stress Index - A Novel Index that Predicts Short and Long Term Mortality of Patients on Continuous Flow Ventricular Assist Devices; __ T. C. Hanff1, J. A. Mazurek1, E. W. Grandin2, A. Padegimas3, J. Howard4, R. Forde-McLean1, J. Wald1, M. A. Acker4, L. R. Goldberg1, P. Atluri4, J. E. Rame1, M. Jessup1, K. B. Margulies1, E. Y. Birati1. 1 _Cardiology, University of Pennsylvania, Philadelphia, PA,_ 2 _Cardiology, Beth Israel Deaconess Medical Center, Boston, MA,_ 3 _Internal Medicine, University of Pennsylvania, Philadelphia, PA,_ 4 _Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA_

**6:30 PM** ( **445)** First In Vitro Results of Local Pump Thrombus Lysis; __ E. Deniz1, C. Feldmann1, A. Stomps2, M. Avsar1, G. Dogan1, S. V. Rojas1, J. S. Hanke1, M. Ricklefs1, A. Haverich1, J. D. Schmitto1. 1 _Department of Cardiothoracic-, Transplantation- and Vascular Surgery, Hannover Medical School, Hannover, Germany,_ 2 _Leibniz University, Hannover, Germany_

**6:35 PM** ( **446)** LVAD Post-Implant Length of Stay Impacts Long Term Survival: An Intermacs Database Analysis; __ S. C. Silvestry1, S. M. Joseph2, S. L. Myers3, D. C. Naftel3, J. K. Kirklin4, S. Prasad5. 1 _Florida Hospital Transplant Institute, Orlando, FL,_ 2 _Center for Advanced Heart & Lung Disease, Baylor University Medical Center, Dallas, TX, _3 _Cardiovascular Thoracic Surgery Research, The University of Alabama at Birmingham, Birmingham, AL,_ 4 _Surgery, University of Alabama, Birmingham, AL,_ 5 _Surgery, University of Rochester, Rochester, NY_

**6:40 PM** ( **447)** Increased Risk of Bleeding Associated with VKORC1 Gene Polymorphism in Patients with Continuous Flow Left Ventricular Assist Devices (CF-LVAD); __ T. Alexy1, W. M. Schultz1, R. T. Cole1, S. R. Laskar1, A. Pekarek1, A. Duncan2, A. L. Smith1, D. J. Vega3, D. Q. Nguyen3, D. Gupta1. 1 _Cardiology, Emory University, School of Medicine, Atlanta, GA,_ 2 _Pathology, Emory University, School of Medicine, Atlanta, GA,_ 3 _Cardiothoracic Surgery, Emory University, School of Medicine, Atlanta, GA_

5:45 PM - 6:45 PM

## MINI ORAL SESSION 18: Patient Centered Outcomes in Advanced Heart and Lung Disease

Location:

Coronado A-C

Target Audience:

NHSAH, ALL

**Chairs:**

Maureen P. Flattery, RN, MS, NP, and Richa Agarwal, MD

**5:45 PM (1095)** Quality of Life Outcomes Among Pediatric Lung Transplant Recipients; __ T. Lazor1, H. Grasemann2, M. Solomon2, S. J. Anthony1. 1 _Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada,_ 2 _Respiratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada_

**5:50 PM** ( **449)** Is Lung Allocation Score Predictive of Survival Among COPD Lung Transplant Registrants and Recipients?; __ H. Maredia1, M. Bowring1, A. Massie1, S. Oyetunji1, C. Merlo2, R. Higgins1, D. Segev1, E. Bush1. 1 _Department of Surgery, Johns Hopkins University, Baltimore, MD,_ 2 _Department of Medicine, Johns Hopkins University, Baltimore, MD_

**5:55 PM** ( **450)** Upper Limb Rehabilitation After Lung Transplantation: A Randomised Controlled Trial; __ L. M. Fuller1, D. El-Ansary2, B. Button1, M. Corbett1, G. Snell3, S. Marasco4, A. E. Holland1. 1 _Physiotherapy Department, Alfred Hospital, Melbourne, Australia,_ 2 _Faculty of Medicine, Dentistry & Health Sciences, Physiotherapy School, University of Melbourne, Melbourne, Australia, _3 _Lung Transplant Services, Alfred Hospital, Melbourne, Australia,_ 4 _Cardiothoracic Surgery Department, Alfred Hospital, Melbourne, Australia_

**6:00 PM** ( **451)** Predictors for Peak Oxygen Uptake in De Novo Heart Transplant Recipients (the HITTS Study); __ K. Rolid, M. Yardley, A. R. Authen, I. Grov, M. R. Kunszt, E. Bjørkelund, E. Gude, A. K. Andreassen, L. Gullestad, K. Nytrøen. _Department of Cardiology, Oslo University Hospital, Oslo, Norway_

**6:05 PM** ( **452)** Do LVAD Patients Need a Specific Diet to Control Weight?; __ K. Vandersmissen1, J. Driesen1, K. Van den Bossche1, W. Droogne2, S. Jacobs1, L. Fresiello1, F. Rega1, K. Gerits1, B. Meyns1. 1 _Department Cardiac Surgery, UZLeuven, Leuven, Belgium,_ 2 _Department of Cardiology, UZLeuven, Leuven, Belgium_

**6:10 PM** ( **453)** Micronutrient Monitoring and Bone Health in Adults with Cystic Fibrosis Undergoing Lung Transplant; __ G. L. Hubert1, T. Tam Chung1, C. Prosser2, D. Lien3, J. Weinkauf3, N. Brown4, M. Goodvin1, K. Jackson1, J. Tabak5, J. Salgado5, A. S. Alzaben6, D. R. Mager6. 1 _Lung Transplant, University of Alberta Hospital, Alberta Health Services, Edmonton, AB, Canada,_ 2 _Laboratory Medicine, University of Alberta Hospital, Alberta Health Services, Edmonton, AB, Canada,_ 3 _Lung Transplant, Division of Pulmonary Medicine, Department of Medicine, University of Alberta, Edmonton, AB, Canada,_ 4 _Adult Cystic Fibrosis, Division of Pulmonary Medicine, Department of Medicine, University of Alberta, Edmonton, AB, Canada,_ 5 _Adult Cystic Fibrosis, University of Alberta Hospital, Alberta Health Services, Edmonton, AB, Canada,_ 6 _Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada_

**6:15 PM** ( **454)** What Does First Person Authorization (FPA) Mean? Knowledge and Attitudes Among FPA Adults Re: Brain Dead Donors (BDDs) and Controlled Donation After Circulatory Determination of Death (cDCDD) Donors - Understanding vs the Law; __ T. M. Egan1, J. J. Requard2, T. P. Edwards3. 1 _Surgery, U. North Carolina Sch Med, Chapel Hill, NC,_ 2 _Lung Banks of America, Chapel Hill, NC,_ 3 _ODUM Institute, U. North Carolina Sch Med, Chapel Hill, NC_

**6:20 PM** ( **455)** Patient and Clinician Perspectives on Usability and Acceptability of a Patient-Centered Decision Aid for Left Ventricular Assist Device Treatment; __ K. M. Kostick1, R. J. Volk2, C. R. Bruce1, S. A. McCurdy3, J. D. Estep4, J. S. Blumenthal-Barby1. 1 _Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX,_ 2 _Department of Health Services Research, the M.D. Anderson Cancer Center, University of Texas, Houston, Houston, TX,_ 3 _School of Public Health, University of Texas, Houston, Houston, TX,_ 4 _Houston Methodist DeBakey Heart & Vascular Center and J.C. Walter Jr. Transplant Center, Houston Methodist Hospital, Houston, TX_

**6:25 PM** ( **456)** Most Survivors Are Glad to Have a VAD; __ L. W. Stevenson1, J. Lindenfeld2, K. Grady3, J. Vader4, M. Givertz1, D. Naftel5, T. Baldwin6, S. Myers7, R. Kormos8, J. K. Kirklin9. 1 _Cardiovascular Division, Brigham & Women's Hospital, Boston, MA, _2 _Cardiovascuar, Vanderbilt, Nashville, TN,_ 3 _Cardiovascular Division, Northwestern Medical Center, Chicago, IL,_ 4 _Cardiovascular Division, Washington University Medical Center, St. Louis, MO,_ 5 _Cardiac Surgery, University of Alabama at Birmingham, Birmingham, AL,_ 6 _National Heart, Lung, and Blood Institute, Bethesda, MD,_ 7 _Cardiovascular Division, University of Alabama at Birmingham, Birmingham, AL,_ 8 _Cardiovascular Division, University of Pittsburg, Pittsburg, PA,_ 9 _Cardiac Surgery, University of Alabama at Birmingham, Birmingham, AL_

**6:30 PM** ( **457)** Slower Gait Speed as a Measure of Frailty Tracks with INTERMACS Profiles, Quality of Life and Predicted Mortality in Ambulatory Patients with Advanced Heart Failure: A Report from the REVIVAL Registry; __ A. Lala1, A. Ambardekar2, J. Estep3, J. Stehlik4, M. Mountis5, D. Haas6, D. Horstmanshof7, J. Thibodeau8, K. Shah9, D. Lanfear10, J. Teuteberg11, W. Taddei-Peters12, S. Khalatbari13, L. Stevenson14, D. Mann15, K. Aaronson13, G. Stewart14. 1 _The Zena and Michael A. Wiener Cardiovascular Institute at Mount Sinai, New York, NY,_ 2 _University of Colorado at Denver, Denver, CO,_ 3 _Houston Methodist Research Institute, Houston, TX,_ 4 _University of Utah, Salt Lake City, UT,_ 5 _Cleveland Clinic Foundation, Cleveland, OH,_ 6 _Abington Memorial Hospital, Abington, PA,_ 7 _INTEGRIS Baptist Medical Center, Oklahoma City, OK,_ 8 _University of Texas Southwestern Medical Center, Dallas, TX,_ 9 _Virginia Commonwealth University, Richmond, VA,_ 10 _Henry Ford Hospital, Detroit, MI,_ 11 _University of Pittsburgh, Pittsburgh, PA,_ 12 _National Heart, Lung and Blood Institute, Bethesda, MD,_ 13 _University of Michigan, Ann Arbor, MI,_ 14 _Brigham and Women's Hospital, Boston, MA,_ 15 _Washington University School of Medicine, St. Louis, MO_

**6:35 PM** ( **458)** Does Functional Status at Listing and Time of Heart Transplant Influence Survival in Heart Transplant Recipients?; __ Y. Ravi1, E. Stock2, S. K. Lella3, J. V. Balasubramaniyan4, L. Copeland5, S. Emani6, C. B. Sai-Sudhakar1. 1 _Cardiac Surgery, Scott & White, Texas A&M, Temple, TX, _2 _Center for Applied Health Research, Veterans Affair, Perry Point, MD,_ 3 _College of Medicine, Texas A &M Health Science Centre, Temple, TX, _4 _Internal Medicine, Sri Ramachandra University, Chennai, India,_ 5 _Center for Applied Health Research, Scott & White, Texas A&M, Temple, TX, _6 _Internal Medicine, The Ohio State University, Columbus, OH_

**6:40 PM** ( **459)** Slow Gait Speed Linked to More Severe Disease but Not with Early Events in Ambulatory Advanced Heart Failure: Results from the Medical Arm of Mechanically Assisted Circulatory Support (MedaMACS) Registry; __ A. V. Ambardekar1, J. Thibodeau2, A. DeVore3, M. Kittleson4, R. Forde-McLean5, M. Palardy6, M. Mountis7, L. Cadaret8, J. Teuteberg9, S. Pamboukian10, L. Stevenson11, R. Xie10, G. Stewart11. 1 _U Colorado, Aurora, CO,_ 2 _UTSW, Dallas, TX,_ 3 _Duke, Durham, NC,_ 4 _Cedars Sinai, Los Angeles, CA,_ 5 _U Pennsylvania, Philadelphia, PA,_ 6 _U Michigan, Ann Arbor, MI,_ 7 _Cleveland Clinic, Cleveland, OH,_ 8 _U Iowa, Iowa City, IA,_ 9 _U Pittsburgh, Pittsburgh, PA,_ 10 _UAB, Birmingham, AL,_ 11 _Brigham, Boston, MA_

# Saturday, April 08, 2017

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 13: Mechanical Circulatory Support - The Interface of Design and Outcome

Location:

Grand Hall A

Target Audience:

MCS, BSTR, EEP, HF, HTX

**Chairs:**

Ulrich Steinseifer, PhD, and Robert L Kormos, MD

**Session Summary:** Despite the advance of mechanical circulatory support systems over the past decade they remain limited by the significant incidence of adverse events (AE). In this session approaches to understand and limit AE such as thrombosis, bleeding and infection will be addressed. Particularly, the role of system component interfaces, smart monitoring and alarms using pressure sensors and data mining techniques, and the "design thinking" paradigm for devices that embody multi-factorial challenges.

7:00 AM

Interfaces and Mechanical Circulatory Support: Challenges and Opportunities for System and Outcome Improvement

Marvin J Slepian, MD, University of Arizona, Tucson, AZ, USA

**7:10 AM** _Q &A_

7:15 AM

Will Pressure Sensors Help in Making Smarter Pumps?

Mark Slaughter, MD, University of Louisville, Louisville, KY, USA

**7:25 AM** _Q &A_

7:30 AM

Anticipation of Adverse Events: Do the Data Speak For Themselves?

Francesco Moscato, PhD, Medical University of Vienna, Vienna, Austria

**7:40 AM** _Q &A_

7:45 AM

Design/Interconnected Thinking for Better Biomedical Devices

J. Yasha Kresh, PhD, Drexel University College of Medicine, Philadelphia, PA, USA

**7:55 AM** _Q &A_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 14: The Tsunami of Adult Congenital Heart Disease (ACHD) Patients Who Need Advanced Therapies: Are We Prepared?

Location:

Grand Hall B

Target Audience:

## HTX, HF, LTX, MCS, PEDS, PH

**Chairs:**

Heather J. Ross, MD, MHSc, FRCPC, and Sanem Nalbantgil, MD

**Session Summary:** A need exists for advanced therapies for Adult Congenital Heart Disease (ACHD) patients. The session will begin with the challenges of bringing ACHD patients to transplant. The session will also include talks on surgical planning and mechanical support options for these patients, accurate imaging evaluation, and treatment of pulmonary hypertension. We will discuss a team based approach to successful outcomes as well as dual organ transplantation and will end with a discussion of allocation in ACHD patients worldwide.

7:00 AM

How to Know When an Adult with Complex Congenital Heart Disease Needs Heart Transplantation

Heather J. Ross, MD, MHSc, FRCPC, Toronto General Hospital, Toronto, ON, Canada

**7:15 AM** _Q &A_

7:20 AM

Surgical Considerations for MCS and Heart Transplant ACHD

Martin Schweiger, MD, Children's Hospital, Zurich, Switzerland

**7:35 AM** _Q &A_

7:40 AM

Care of the ACHD Patient After MCS or Heart Transplant: The Challenge is Just Beginning

Jonathan Menachem, MD, Hospital of the University of Pennsylvania, Philadelphia, PA, USA

**7:55 AM** _Q &A_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 15: Extracorporeal Photopheresis: Shedding Light on Rejection?

Location:

Grand Hall C

Target Audience:

LTX, BSTR, HTX, ID, NHSAH, PATH, PEDS, PHARM

**Chairs:**

Matthew R Morrell, MD, and Christian Benden, MD

**Session Summary:** This session will explore mechanisms of and clinical indications for extracorporeal photopheresis (ECP) with a goal to increase understanding of the possible benefits of ECP and adoption of this therapy in lung and heart transplant recipients.

7:00 AM

ECP: Everything Under the Sun

Jill Adamski, MD, PhD, Mayo Clinic Arizona, Phoenix, AZ, USA

**7:17 AM** _Q &A_

7:20 AM

ECP in Heart Transplantation: Have the Lights Gone Out?

Andreas Zuckermann, MD, Medical University of Vienna, Vienna, Austria

**7:37 AM** _Q &A_

7:40 AM

ECP in Lung Transplantation: Light at the End of the Tunnel?

Mark Greer, MB Bch, Hannover Medical School, Hannover, Germany

**7:57 AM** _Q &A_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 16: Pregnant - Scared? So Are We.... Management of Pregnancy in Our Complex Patients

Location:

Seaport F-H

Target Audience:

PHARM, HTX, LTX, MCS, NHSAH, PEDS

**Chairs:**

Susan M Joseph, MD, and Christa Kirk, PharmD

**Session Summary:** Women of reproductive age account for over 1/3 of all SOT recipients. Most are advised to avoid pregnancy for several years post-transplant, if not altogether. However, as outcomes post-transplant continue to improve, more women are able to consider pregnancy. There are numerous risks to the transplant recipient, organ, and fetus. Hence, there is a great need for expertise in addressing family planning, fertility, contraception, and care during and after pregnancy.

7:00 AM

The Facts of Life: Pregnancy after Thoracic Organ Transplant

Robin Vos, MD, PhD, KU Leuven, Leuven, Belgium

**7:10 AM** _Q &A_

7:15 AM

Labor of Love: Pregnancy in the Heart Failure / Congenital Population

Leigh C Reardon, MD, UCLA Medical Center, Los Angeles, CA, USA

**7:25 AM** _Q &A_

7:30 AM

In the Mix: Orchestrating the Multidisciplinary Care of the Post-Transplant/MCS/Complex Congenital Pregnant Patient

Mary Canobbio, RN, FAAN, UCLA Medical Center, Los Angeles, CA, USA

**7:40 AM** _Q &A_

7:45 AM

Treating the Mother, Protecting the Baby: Drug Therapy During and After Pregnancy

Jennifer Eshelman, PharmD, Children's Hospital Colorado, Aurora, CO, USA

**7:55 AM** _Q &A_

7:00 AM - 8:00 AM

## SUNRISE SYMPOSIUM 17: Living in a 'Bacterial' World: Microbiome in Thoracic Transplantation

Location:

Coronado A-C

Target Audience:

BSTR, ALL

**Chairs:**

Howard Eisen, MD, and Bryan Coburn, MD, PhD, FRCPC

**Session Summary:** The goal of this session is to explore the role of the microbiome in affecting posttransplant outcomes or in reflecting the extent of immunosuppression. Discussion swill include an overview of the effect of the microbiome on health and disease followed by transplant specific considerations. Included in this is the question of whether changes in the bacterial or viral micro biome can be used to reflect the extent of immunosuppression, thus facilitating modulation of immunosuppression to improve outcomes.

7:00 AM

The Microbiome in Health and Disease

W. H. Wilson Tang, MD, Cleveland Clinic Foundation, Cleveland, OH, USA

**7:10 AM** _Q &A_

7:15 AM

Microbiome in Transplantation

Maria-Luisa Alegre, MD PhD, University of Chicago, Chicago, IL, USA

**7:25 AM** _Q &A_

7:30 AM

The Microbiome and Immunosuppression in Heart Transplant

Kiran Khush, MD, MAS, Stanford University, Stanford, CA, USA

**7:40 AM** _Q &A_

7:45 AM

Microbiome in Lung transplantation and Gut-Lung Axis

Sangeeta M Bhorade, MD, Northwestern Memorial Hospital, Chicago, IL, USA

**7:55 AM** _Q &A_

8:00 AM - 9:30 AM

## ORAL SESSION 41: The Rhythm is Going to Get You: EP Issues in MCS

Location:

Seaport A-E

Target Audience:

MCS, HF, NHSAH

**Chairs:**

Ayesha K. Hasan, MD, and Daniel Zimpfer, MD

**8:00 AM** ( **460)** Cardiac Resynchronization Therapy Reduces Mortality and Cardiovascular Readmissions in Left Ventricular Assist Device Recipients; __ A. R. Garan1, X. Mai1, V. K. Topkara1, K. Takeda1, K. J. Clerkin1, R. Demmer1, M. Yuzefpolskaya1, H. Takayama1, Y. Naka1, J. Chyou2, H. M. Spotnitz1, N. Uriel3, J. Dizon1, P. C. Colombo1. 1 _Columbia University, New York, NY,_ 2 _SUNY Stonybrook, Stonybrook, NY,_ 3 _University of Chicago, Chicago, IL_

**8:15 AM** ( **461 )** Survival Benefit of Implantable Cardioverter Defibrillator Therapy on Patients with Left Ventricular Assist Device; __ E. Simsek1, S. Nalbantgil1, E. Demir1, H. S. Kemal2, I. Mutlu1, P. Ozturk3, S. Ertugay3, C. Engin3, T. Yagdi3, M. Ozbaran3. 1 _Cardiology, Ege University School of Medicine, Izmir, Turkey,_ 2 _Cardiology, Near East University School of Medicine, Lefkosa, Cyprus,_ 3 _Cardiovascular Surgery, Ege University School of Medicine, Izmir, Turkey_

**8:30 AM** ( **462)** Impact of Cardiac Resynchronization Therapy (CRT) on Invasive Hemodynamics and Echocardiographic Parameters in Patients with Implanted Left Ventricular Assist Devices (LVADs); __ S. Adatya1, D. M. Tehrani1, N. Sarswat1, G. H. Kim1, J. Raikhelkar1, C. Juricek1, V. Kagan1, T. Ota1, D. Burkhoff2, G. Sayer1, V. Jeevanandam1, N. Uriel1. 1 _University of Chicago, Chicago, IL,_ 2 _Heartware International, Inc, Framingham, MA_

**8:45 AM** ( **463)** Right Ventricular Pacing Improves Functional Status and Quality of Life Compared to Biventricular Pacing in Left Ventricular Assist Device Patients; __ J. Grinstein1, D. Medvedofsky1, E. Flatley1, J. Moss2, D. Beiser1, S. Adata1, G. Sayer1, N. Sarswat1, J. Raikhelkar1, G. H. Kim1, V. Kagan1, W. Lee1, T. Ota1, V. Jeevanandam1, R. Lang1, N. Uriel1. 1 _University of Chicago, Chicago, IL,_ 2 _University of California San Francisco, San Francisco, CA_

**9:00 AM** ( **464)** Postoperative Atrial Fibrillation After Left Ventricular Assist Device Placement Increases Morbidity and Resource Utilization; __ R. B. Hawkins1, A. Guo1, J. Mehaffey1, C. Fonner2, A. Speir3, J. Rich2, M. Quader4, G. Ailawadi1, L. Yarboro1. 1 _University of Virginia, Charlottesville, VA,_ 2 _Virginia Cardiac Services Quality Initiative, Falls Church, VA,_ 3 _INOVA Heart and Vascular Institute, Falls Church, VA,_ 4 _Virginia Commonwealth University, Charlottesville, VA_

**9:15 AM** ( **465)** Comparison of Survival and Modes of Death by ICD Status Among LVAD Recipients; __ X. Mai, K. Clerkin, V. K. Topkara, K. Takeda, R. Demmer, M. Yuzefpolskaya, M. Tiburcio, H. Takayama, Y. Naka, H. M. Spotnitz, J. Dizon, P. C. Colombo, A. R. Garan. _Columbia University, New York, NY_

8:00 AM - 9:30 AM

## ORAL SESSION 42: The Weighting Game: Impact of Obesity, Age, and Other Comorbidities in MCS

Location:

Grand Hall A

Target Audience:

MCS, HF, HTX, NHSAH

**Chairs:**

Theodoros Kofidis, MD, PhD, FRCS, and Brent C Lampert, DO

**8:00 AM** ( **466)** Clinical Outcomes of Adults with Elevated Body Mass Index with Destination Therapy: An Analysis of INTERMACS Registry; __ A. Jaiswal1, L. Myers2, V. K. Topkara3, P. C. Colombo3, D. Baran4, T. H. Le Jemtel1. 1 _Cardiology, Tulane Heart and Vascular Institute, New Orleans, LA,_ 2 _Global Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA,_ 3 _Cardiology, Columbia University Medical Center-New York Presbyterian, New York, NY,_ 4 _Heart Transplantation, Newark Beth Israel Medical Center, Newark, NJ_

**8:15 AM** ( **467)** Impact of Morbid Obesity After Left Ventricular Assist Device Placement; __ L. Coyle, G. Yost, C. Gallagher, N. Graney, R. Siemeck, G. Bhat, A. Tatooles. _Heart and Vascular Institue, Advocate Christ Medical Center, Oak Lawn, IL_

**8:30 AM** ( **468)** Factors Associated with Prolonged Survival in Destination Therapy LVAD Recipients; __ Y. Xia1, S. Forest1, P. Friedmann1, L. Chou1, S. Patel2, U. Jorde3, D. Goldstein1. 1 _Cardiovascular and Thoracic Surgery, Montefiore Medical Center, Bronx, NY,_ 2 _Internal Medicine, Cardiology, Montefiore Medical Center, Bronx, NY,_ 3 _Medicine, Cardiology, Montefiore Medical Center, Bronx, NY_

**8:45 AM** ( **469)** How Old Is Too Old? The Influence of Advanced Age on VA-ECMO Outcomes; __ M. Salna1, K. Takeda2, P. Kurlansky2, H. Ikegami2, J. Han1, S. Stein2, V. Topkara3, M. Yuzefpolskaya3, P. C. Colombo3, Y. Naka2, A. R. Garan3, H. Takayama2. 1 _Columbia University College of Physicians and Surgeons, New York, NY,_ 2 _Surgery (Cardiothoracic), Columbia University Medical Center, New York, NY,_ 3 _Medicine (Cardiology), Columbia University Medical Center, New York, NY_

**9:00 AM** ( **470)** Proteinuria in Patients Receiving Left Ventricular Assist Devices Is Highly Associated with Renal Failure and Mortality; __ R. Muslem1, K. Caliskan1, S. Akin1, D. A. Hesselink2, G. Whitman3, R. J. Tedford4, A. J. Bogers5, O. C. Manintveld1, S. D. Russell4. 1 _Cardiology, Erasmus MC, Rotterdam, Netherlands,_ 2 _Nephrology, Erasmus MC, Rotterdam, Netherlands,_ 3 _Cardiac Surgery, Johns Hopkins School of Medicine, Baltimore, MD,_ 4 _Cardiology, Johns Hopkins School of Medicine, Baltimore, MD,_ 5 _Cardiac Surgery, Erasmus MC, Rotterdam, Netherlands_

**9:15 AM** ( **471)** Adverse Events After Device Implantation Are More Common in Obese Patients: An IMACS Registry Analysis; __ S. J. Forest1, R. Xie2, J. K. Kirklin2, J. A. Cowger3, Y. Xia1, A. I. Dipchand4, C. Sivathasan5, C. Merry6, L. H. Lund7, R. Kormos8, T. Nakatani9, U. Jorde10, D. J. Goldstein1. 1 _Cardiothoracic and Vascular Surgery, Montefiore Medical Center, Bronx, NY,_ 2 _The James and John Kirklin Institute for Research in Surgical Outcomes (KIRSO)/UAB, Birmingham, AL,_ 3 _St. Vincent Heart Center of Indiana, Indianapapolis, IN,_ 4 _Hospital for Sick Children, Toronto, ON, Canada,_ 5 _National Heart Centre Singapore, Singapore, Singapore,_ 6 _Fiona Stanley Hospital, Perth, Australia,_ 7 _Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden,_ 8 _Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA,_ 9 _Maki Hospital, Osaka, Japan,_ 10 _Medicine, Montefiore Medical Center, Bronx, NY_

8:00 AM - 9:30 AM

## ORAL SESSION 43: In the Mix of Heart Failure

Location:

Grand Hall B

Target Audience:

HF, BSTR, NHSAH, PHARM

**Chairs:**

Ivan Knezevic, MD, and Michael M. Givertz, MD

**8:00 AM** ( **472)** Exosome Signaling in Heart Failure; __ H. Basma, K. Dhar, D. R. Anderson, L. M. Smith, S. Rennard, B. D. Lowes. _Internal Medicine, UNMC, OMAHA, NE_

**8:15 AM** ( **473)** The Effects of CD34+ Cell Therapy in Heart Failure with Preserved Ejection Fraction; __ B. Vrtovec1, G. Poglajen1, G. Zemljic1, S. Frljak1, A. Cerar1, R. Okrajsek1, M. Jaklic1, F. Haddad2. 1 _Advanced Heart Failure and Transplantation Center, UMC Ljubljana, Ljubljana, Slovenia,_ 2 _Stanford Cardiovascular Institute, Stanford, CA_

**8:30 AM** ( **474)** Leukocyte Time-Dependent Biology and Outcomes in Advanced Heart Failure; __ G. Bondar1, M. Cadeiras1, N. Wisniewski1, A. Esmaeili1, G. Godoy1, J. Maque1, E. Chang1, M. Bakir1, S. Kupiec-Weglinski2, D. Chu1, T. Bao1, J. Hai1, R. Yee1, A. Li1, M. Rai1, D. Tran1, L. Madrigal1, R. Togashi1, P. Ping3, E. Reed4, M. Deng1. 1 _Medicine/Cardiology, David-Geffen Sch Med, Los Angeles, CA,_ 2 _Agriculture and Life Science, Cornell University, Ithaca, NY,_ 3 _Physiology, David-Geffen Sch Med, Los Angeles, CA,_ 4 _Pathology & Laboratory Medicine-Immunogenetics Center, David-Geffen Sch Med, Los Angeles, CA_

**8:45 AM** ( **475)** Multi-Omic Biomarker Signatures Are Predictive of 9-Month Patient Outcomes in Subjects with Advanced Heart Failure; __ A. Singh, C. P. Shannon, S. Assadian, M. Toma, V. Chen, L. Dai, K. K. Lam, Z. Hollander, R. T. Ng, S. J. Tebbutt, B. M. McManus. _University of British Columbia, Vancouver, BC, Canada_

**9:00 AM** ( **476)** Abnormalities of Cardiolipin Synthesis and Remodeling in Heart Failure: A Cornerstone of Energy Deprivation; __ H. N. Sabbah. _Henry Ford Health System, Detroit, MI_

**9:15 AM** ( **477)** Increased Right Ventricular Sympathetic Activity and Oxygen Consumption in Patients with Right Ventricular Dysfunction; __ A. Ahmadi, J. M. Renaud, S. Promislow, I. Burwash, G. Dwivedi, J. Zelt, R. A. deKemp, R. S. Beanlands, L. M. Mielniczuk. _University of Ottawa Heart Institute, Ottawa, ON, Canada_

8:00 AM - 9:30 AM

## ORAL SESSION 44: Optimizing Early Outcomes after Lung Transplantation

Location:

Grand Hall C

Target Audience:

LTX, BSTR, ID, PATH, PHARM

**Chairs:**

Hilary J Goldberg, MD, and Monique Malouf, FRACP

**8:00 AM** ( **478)** Relationship of Early Lung Allograft Injury as Measured by Cell Free DNA with Donor and Recipient Characteristics; __ S. M. Pham1, S. Agbor-Enoh2, P. Shah3, I. Timofte4, S. Nathan5, J. Orens3, A. Brown5, S. Gorham2, K. Bhatti2, A. Marishta2, M. Jang2, Y. Yang2, U. Fideli2, I. Tunc2, J. Zhu2, A. Iacono6, H. Valantine2. 1 _Surgery, University of Maryland, Baltimore, MD,_ 2 _NIH, Bethesda, MD,_ 3 _Johns Hopkins University, Baltimore, MD,_ 4 _Medicine, University of Maryland, Baltimore, MD,_ 5 _Inova, Fall Church, VA,_ 6 _University of Maryland, Baltimore, MD_

**8:15 AM** ( **479)** Cell-Free DNA in Human Ex-Vivo Lung Perfusate as a Potential Biomarker to Predict the Risk of Primary Graft Dysfunction (PGD) in Lung Transplantation; __ T. Kanou1, R. Zamel1, M. Chen1, D. Nakajima1, Y. Watanabe1, L. Ding1, S. Azad1, T. K. Waddell1, K. Nakahira2, A. M. Choi2, M. Cypel1, M. Liu1, S. Keshavjee1. 1 _Latner Thoracic Surgery Research Laboratories, Toronto General Research Institute, Toronto, ON, Canada,_ 2 _Division of Pulmonary and Critical Care Medicine, Weill Cornell Medicine, New York, NY_

**8:30 AM** ( **483)** Early CMV Management Post Lung Transplant(LTx): A 6-Year Review of Pre-Emptive Strategy for CMV; __ K. Santhanakrishnan, E. Karimi, N. Yonan, M. Alaloul, R. Venkateswaran, K. Heyes. _Transplant Department, Wythenshawe Hospital, Manchester, United Kingdom_

**8:45 AM** ( **481)** Gene Expression Profiling of Bronchoalveolar Lavage Cells During Lung Allograft Acute Rejection; __ S. S. Weigt1, X. Wang1, V. Palchevskiy1, N. D. Patel1, D. J. Ross1, J. M. Reynolds2, P. Shah3, L. Singer4, M. Budev5, S. Palmer2, J. A. Belperio1. 1 _UCLA, Los Angeles, CA,_ 2 _Duke University, Durham, NC,_ 3 _Johns Hopkins, Baltimore, MD,_ 4 _University of Toronto, Toronto, ON, Canada,_ 5 _Cleveland Clinic, Cleveland, OH_

**9:00 AM** ( **482)** Treatment of Antibody Mediated Rejection of the Lung Allograft with Carfilzomib-Based Therapy; __ C. R. Ensor, A. Zeevi, S. A. Yousem, M. Mangiola, M. Marrari, M. R. Morrell, J. M. Pilewski, J. D'Cunha, J. F. McDyer. _University of Pittsburgh, Pittsburgh, PA_

**9:15 AM** ( **480)** The Association of IL-6 and IL-8 within 72 Hours Post-Transplant and Short and Long Term Outcome; __ S. E. Verleden, A. Martens, E. Vandermeulen, H. Bellon, T. Heigl, A. Sacreas, A. Neyrinck, A. van Herck, D. Van Raemdonck, G. Verleden, B. Vanaudenaerde, R. Vos. _KU Leuven, Leuven, Belgium_

8:00 AM - 9:30 AM

## ORAL SESSION 45: Heart Transplant in Special Populations

Location:

Grand Hall D

Target Audience:

HTX, HF, MCS

**Chairs:**

Jacqueline M. Smits, MD, PhD, and Tobias Deuse, MD, PhD

**8:00 AM** ( **484)** Heart Transplantation and Bridge with Mechanical Circulatory Support in Cardiac Sarcoidosis: An Analysis of the UNOS Registry; __ T. C. Crawford1, J. T. Magruder1, J. Grimm1, A. Suarez Pierre1, B. A. Houston2, K. Mandal1, K. J. Zehr1, G. J. Whitman1, R. J. Tedford3, S. D. Russell3, N. A. Gilotra3. 1 _Surgery, Johns Hopkins University, Baltimore, MD,_ 2 _Medicine, Medical University of South Carolina, Charleston, SC,_ 3 _Medicine, Johns Hopkins University, Baltimore, MD_

**8:15 AM** ( **485)** Survival After Heart Transplantation in Patients with Cardiac Sarcoidosis - A UNOS Registry Analysis; __ S. Madan1, S. R. Patel1, D. Sims1, J. Shin1, D. Goldstein2, U. P. Jorde1, O. Saeed1. 1 _Cardiology, Montefiore Medical Center/Albert Einstein College of Medicine, New York, NY,_ 2 _Cardiovascular and Thoracic Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, New York, NY_

**8:30 AM** ( **486)** Heart Transplantation in Muscular Dystrophy Patients: Is It a Viable Option?; __ R. Rizwan1, J. L. Jefferies2, R. Bryant III1, G. A. Pettengill1, T. D. Ryan2, A. Lorts2, C. Chin2, F. Zafar1, D. L. Morales1. 1 _Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH,_ 2 _Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH_

**8:45 AM** ( **487)** The Effect of Pre-Heart Transplant Obesity on Post-Transplant Mortality: An Analysis of the ISHLT Registry Data; __ B. S. Doumouras1, C. S. Fan2, A. I. Dipchand3, C. Manlhiot2, J. Stehlik4, H. J. Ross1, A. C. Alba1. 1 _Heart Failure and Transplant Program, Toronto General Hospital, University Health Network, University of Toronto, Toronto, ON, Canada,_ 2 _CV Data Management Centre, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada,_ 3 _Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada,_ 4 _University of Utah School of Medicine, Salt Lake City, UT_

**9:00 AM** ( **488)** Young African American Heart Transplant Recipients Have an Elevated Risk of Post-Transplant Mortality; __ H. Maredia1, M. Bowring1, A. Massie1, S. Oyetunji1, C. Merlo2, R. Higgins1, D. Segev1, E. Bush1. 1 _Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD,_ 2 _Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD_

**9:15 AM** ( **489)** The Psychosocial Treadmill - Working Out a Way to Improve High Risk Psychosocial Behaviors in Heart Transplant Candidates; __ L. Newman, A. Kilic, A. K. Hasan, S. Smith, S. Emani, B. Whitson, B. C. Lampert. _The Ohio State University Wexner Medical Center, Columbus, OH_

8:00 AM - 9:30 AM

## ORAL SESSION 46: Rogue One: A Graft Wars Story of Rejection and Tolerance

Location:

Seaport F-H

Target Audience:

BSTR, HF, HTX, LTX, PATH, PEDS, PHARM

**Chairs:**

Tereza Martinu, MD, PhD, and Stijn E Verleden, PhD

**8:00 AM** ( **490)** Chronic Airway Fibrosis in Orthotopic Mouse Lung Transplantation Models - An Experimental Reappraisal; __ L. Dubs1, Y. Yamada1, J. Jang1, T. Martinu2, D. Kenkel3, K. Windirsch1, I. Inci1, B. Vanaudenaerde4, A. Boss3, W. Weder1, W. Jungraithmayr1. 1 _Division of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland,_ 2 _University of Toronto, Toronto, ON, Canada,_ 3 _Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland,_ 4 _Laboratory of Pneumology, Katholieke Universiteit Leuven, Leuven, Belgium_

**8:15 AM** ( **491)** Ischemia Reperfusion Injury Augments Acute and Chronic Rejection and Alloimmune-Dependent Intrapulmonary Lymphoid Neogenesis in a Mouse Orthotopic Lung Transplant Model; __ T. Watanabe1, T. Martinu1, H. Oishi2, M. Horie3, D. Hwang1, Z. Guan1, M. Liu1, S. Keshavjee1, S. Juvet1. 1 _Latner Thoracic Surgery Research Laboratories, University Health Network, Toronto, ON, Canada,_ 2 _Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan,_ 3 _Cardiothoracic Division, Department of Medical Imaging, Time Resolved Imaging and Image Optimization, University Health Network, Toronto, ON, Canada_

**8:30 AM** ( **492)** Linking Chronic Lung Allograft Dysfunction with Early Immunologic Events in a Humanized Mouse Model; __ T. Siemeni1, A. Knöfel1, F. Ius1, K. Jansson1, J. Salman1, W. Sommer1, M. Avsar1, C. Kühn1, C. Falk2, A. Haverich1, G. Warnecke1. 1 _Hannover HTTG, Hannover, Germany,_ 2 _Institute of Transplant Immunology, Hannover, Germany_

**8:45 AM** ( **493)** Selective Reprogramming and Recapitulation of CD4 and CD8 T Cells in the Neonate to Induce Tolerance to Heart Transplants; __ R. A. Bascom, K. Tao, L. J. West. _University of Alberta, Edmonton, AB, Canada_

**9:00 AM** ( **494)** Two Months Delayed Induction of Mixed Chimerism After Heart and Kidney Cotransplantation in Nonhuman Primates; __ K. Huh1, W. Sommer1, K. A. Robinson1, X. Wu1, J. T. Paster1, I. Hanekamp1, A. Dehnadi1, T. Kawai1, R. N. Smith2, R. Colvin3, G. Benichou1, J. Madsen1. 1 _Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Boston, MA,_ 2 _Department of Pathology, Massachusetts General Hospital, Boston, MA,_ 3 _Center for Transplantation Sciences, Department of Pathology, Massachusetts General Hospital, Boston, MA_

**9:15 AM** ( **495)** Generating Hypoimmunogenic Murine Induced Pluripotent Stem Cells by the Disruption of beta-2-Microglobulin; __ X. Hu1, T. Deuse2, N. Kooreman3, M. Alawi4, G. Tediashvili1, H. Reichenspurner5, S. Schrepfer1. 1 _Surgery, TSI Lab, UCSF, San Francisco, CA,_ 2 _CT Surgery, UCSF, San Francisco, CA,_ 3 _Cardiovascular Medicine, Stanford University, Stanford, CA,_ 4 _Heinrich Pette, UKE, Hamburg, Germany,_ 5 _Cardiovascular Surgery, UHZ, Hamburg, Germany_

9:45 AM - 11:45 AM

## PLENARY SESSION

Location:

Seaport A-E

Target Audience:

ALL

**Chairs:**

Andrew J Fisher, PhD FRCP, and Christian Benden, MD FCCP

**9:45 AM** Awards Presentations

10:15 AM

Using the Financial Markets to Fund Early-Stage Drug Development

Roger M Stein, PhD, MIT Laboratory for Financial Engineering, Boston, MA, USA

**10:40 AM** ( **496)** Advanced Therapy Utilization and Survival in Ambulatory Patients with Advanced Heart Failure: Results from the Medical Arm of Mechanically Assisted Circulatory Support (MedaMACS) Registry; __ A. V. Ambardekar1, M. Kittleson2, M. Palardy3, M. Mountis4, R. Forde-McLean5, A. DeVore6, S. Pamboukian7, J. Thibodeau8, J. Teuteberg9, L. Cadaret10, R. Xie7, L. Stevenson11, G. Stewart11. 1 _U Colorado, Aurora, CO,_ 2 _Cedars, Los Angeles, CA,_ 3 _U Michigan, Ann Arbor, MI,_ 4 _Cleveland Clinic, Cleveland, OH,_ 5 _U Penn, Philadelphia, PA,_ 6 _Duke, Durham, NC,_ 7 _UAB, Birmingham, AL,_ 8 _UTSW, Dallas, TX,_ 9 _U Pitt, Pittsburgh, PA,_ 10 _U Iowa, Iowa City, IA,_ 11 _Brigham, Boston, MA_

10:55 AM

Interactive Discussant

Luciano Potena, MD, PhD, University of Bologna, Bologna, Italy

11:00 AM

PRESIDENT'S DEBATE (PRO): We Must Take Greater Risks for the Sake of Our Patients!

Lori J West, MD, DPhil, University of Alberta, Edmonton, AB, Canada

11:20 AM

PRESIDENT'S DEBATE (CON): We Must Take Greater Risks for the Sake of Our Patients!

Allan R Glanville, MBBS, MD, FRACP, St. Vincent's Hospital, Sydney, Australia

12:00 PM - 1:30 PM

## ORAL SESSION 47: Not the Usual Suspects: Driving Outcomes in MCS

Location:

Seaport A-E

Target Audience:

MCS, HF, HTX, NHSAH

**Chairs:**

Markus Johannes Barten, MD, PhD, and Maria M. Mountis, DO

**12:00 PM** ( **497)** The Effects of Patient Blood Pressure on the Occurrence of Serious Adverse Events in the ENDURANCE Trial; __ J. A. Cowger1, J. G. Rogers2, C. A. Milano2, J. J. Teuteberg3, N. A. Mokadam4, E. J. Birks5, S. W. Boyce6, K. D. Aaronson7, F. D. Pagani7. 1 _St. Vincent Heart Center, Indianapolis, IN,_ 2 _Duke University Medical Center, Durham, NC,_ 3 _University of Pittsburgh Medical Center, Pittsburgh, PA,_ 4 _University of Washington, Seattle, WA,_ 5 _University of Louisville, Louisville, KY,_ 6 _MedStar Health, Washington, DC,_ 7 _University of Michigan Medical Center, Ann Arbor, IL_

**12:15 PM** ( **498)** How Does the Pulse Pressure Impact on Cerebral Autoregulation Between Axial and Centrifugal LVAD?; __ M. Ono1, S. K. Singh2, K. K. Kibler1, B. R. Easley1, O. H. Frazier1, K. M. Brady1. 1 _Baylor College of Medicine, Houston, TX,_ 2 _Brigham & Women's Hospital, Boston, MA_

**12:30 PM** ( **499)** The Hemodynamic Effects of Intravascular Ventricular Assist System (iVAS) in Advanced Heart Failure Patients Awaiting Heart Transplant; __ V. Jeevanandam1, D. Onsager1, T. Song1, B. Chung2, T. Ota1, C. Juricek1, T. Lammy1, N. Uriel3. 1 _CT Surgery, University of Chicago, Chicago, IL,_ 2 _University of Chicago, Chicago, IL,_ 3 _Cardiology, University of Chicago, Chicago, IL_

**12:45 PM** ( **500)** Temporal Patterns of Adverse Events (AE) Occurring within 60 Days of LVAD Implantation: The Concept of the AE Cascade; __ J. O. Larsen1, A. D. Althouse2, J. J. Teuteberg3, C. M. Sciortino4, C. V. Nikas1, L. F. Lagazzi4, M. S. Sharbaugh2, S. U. Iturra1, N. M. Kunz2, E. M. Dunn2, K. L. Lockard2, R. L. Kormos4. 1 _University of Pittsburgh School of Medicine, Pittsburgh, PA,_ 2 _Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA,_ 3 _Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA,_ 4 _Cardiothoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA_

**1:00 PM** ( **501)** Sex-Specific Outcome Disparities in Patients Receiving Continuous-Flow Left Ventricular Assist Devices: A Systematic Review and Meta-Analysis; __ V. Blumer, R. Mendirichaga, S. Chaparro. _University of Miami, Miami, FL_

**1:15 PM** ( **502)** A Multi-Institutional Study of Mechanical Circulatory Support in Adult Congenital Heart Disease: Is This an Effective Therapy?; __ A. M. Cedars1, C. Vanderpluym2, D. Koehl3, R. Cantor3, J. K. Kirklin4. 1 _Cardiology, Baylor University Medical Center, Dallas, TX,_ 2 _Cardiology, Boston Children's Hospital, Boston, MA,_ 3 _Kirklin Institute for Research in Surgical Outcomes, University of Alabama Birmingham, Birmingham, AL,_ 4 _Cardiothoracic Surgery, University of Alabama Birmingham, Birmingham, AL_

12:00 PM - 1:30 PM

## ORAL SESSION 48: Seeing the Patient Beyond the Device

Location:

Grand Hall A

Target Audience:

MCS, HF, NHSAH

**Chairs:**

Jennifer A. Beckman, MSN-FNP, RN, CHFN, and Samer S Najjar, MD

**12:00 PM** ( **503)** Health-Related Quality of Life and Treatment Preferences in Ambulatory Heart Failure - Results from the REVIVAL Study; __ J. Stehlik1, M. Mountis2, D. Haas3, M. Palardy4, A. Ambardekar5, J. Estep6, G. Ewald7, S. Russell8, S. Robinson9, U. Jorde10, N. Jeffries11, C. Spino4, J. T. Baldwin11, D. Mann7, G. Stewart12, K. Aaronson4, .. for the REVIVAL Investigators1. 1 _University of Utah School of Medicine, Salt Lake City, UT,_ 2 _Cleveland Clinic Foundation, Cleveland, OH,_ 3 _Abington Memorial Hospital, Abington, PA,_ 4 _University of Michigan, Ann Arbor, MI,_ 5 _University of Colorado, Denver, CO,_ 6 _Houston Methodist Research Institute, Houston, TX,_ 7 _Washington University School of Medicine, St. Louis, MO,_ 8 _The Johns Hopkins University School of Medicine, Baltimore, MD,_ 9 _University of Maryland, Baltimore, MD,_ 10 _Montefiore Medical Center, New York City, NY,_ 11 _National Heart, Lung and Blood Institute, Bethesda, MD,_ 12 _Brigham and Women's Hospital, Boston, MA_

**12:15 PM** ( **504)** Glad to Have a VAD Across Intermacs Profiles; __ F. Pagani1, M. Kittleson2, G. Stewart3, A. DeVore4, M. Brinkley5, S. Myers6, M. Miller7, D. Naftel6, J. J. Teuteberg8, L. W. Stevenson2. 1 _Cardiac Surgery, University of Michigan, Ann Arbor, MI,_ 2 _Brigham & Women's Hospital, Boston, MA, _3 _Cardiovascular Medicine, Brigham & Women's Hospital, Boston, MA, _4 _Cardiology, Duke University Medical Center, Durham, NC,_ 5 _Cardiology, Vanderbilt Medical Center, Nashville, TN,_ 6 _Cardiac Surgery, University of Alabama at Birmingham, Birmingham, AL,_ 7 _National Heart Lung and Blood Institute, Bethesda, MD,_ 8 _Cardiology, University of Pittsburg, Pittsburg, PA_

**12:30 PM** ( **505)** Destination Therapy: Targeting & Refining Advance Care Planning; __ J. Woodburn1, L. L. Staley1, S. E. Wordingham2, J. Spadafore1, E. Boldea1, H. M. Ross1, D. E. Steidley3, O. E. Pajaro1. 1 _Cardiothoracic Surgery, Mayo Clinic, Phoenix, AZ,_ 2 _Palliative Medicine, Mayo Clinic, Phoenix, AZ,_ 3 _Cardiology/Transplant, Mayo Clinic, Phoenix, AZ_

**12:45 PM** ( **506)** Long Term Neurocognitive Outcomes After Left Ventricular Assist Device Implantation; __ R. J. Petrucci1, S. C. Feitell2, E. J. Gracely3, K. L. Corvi4, T. Rowe5, J. W. Entwistle6. 1 _Psychiatry, Drexel College of Medicine, Philadelpha, PA,_ 2 _Cardiology, Rochester Regional Health System, Rochester, NY,_ 3 _Family, Community and Preventative Medicine, Drexel College of Medicine, Philadelpha, PA,_ 4 _Psychology, Philadelphia College of Osteopathic Medicine, Philadelpha, PA,_ 5 _Cardiology, Drexel College of Medicine, Philadelpha, PA,_ 6 _Surgery, Thomas Jefferson Univ, Philadelpha, PA_

**1:00 PM** ( **507)** Reducing 30-Day Hospital Readmission Rate in Left Ventricular Assist Device Patients with a Structured Readmission Improvement Plan; __ D. B. Sims1, A. Luke2, S. Rangasamy1, E. Borukhov2, O. Saeed1, S. Murthy1, S. Patel1, J. J. Shin1, D. J. Goldstein2, U. P. Jorde1. 1 _Cardiology, Montefiore Medical Center, New York, NY,_ 2 _Cardiovascular and Thoracic Surgery, Montefiore Medical Center, New York, NY_

**1:15 PM** ( **508)** Impact of Patient Distance from VAD Implanting Center on Outcomes; __ J. A. Cowger1, P. Shah2, R. Singh3, K. D. Aaronson4, F. D. Pagani5, J. Stulak6, S. M. Dunlay7, T. F. Dardas8, N. A. Mokadam9, C. T. Salerno10, A. Ravichandran11. 1 _St. Vincent Heart Center of Indiana, Carmel, IN,_ 2 _Cardiovascular Medicine, Inova Heart & Vascular Institute, Falls Church, VA, _3 _Surgery, Inova Heart & Vascular Institute, Falls Church, VA, _4 _Cardiovascular Medicine, University of Michigan, Ann Arbor, MI,_ 5 _Cardiac Surgery, University of Michigan, Ann Arbor, MI,_ 6 _Cardiac Surgery, Mayo Clinic, Rochester, MN,_ 7 _Cardiovacular Medicine, Mayo Clinic, Rochester, MN,_ 8 _Cardiovascular Medicine, University of Washington, Seattle, WA,_ 9 _Cardiovascular Surery, University of Washington, Seattle, WA,_ 10 _Cardiac Surgery, St. Vincent Heart Center of Indiana, Carmel, IN,_ 11 _Cardiovascular Medicine, St. Vincent Heart Center of Indiana, Indianapolis, IN_

12:00 PM - 1:30 PM

## ORAL SESSION 49: Antibodies and Other Determinants of Cardiac Rejection: Let's ROCK and Rho

Location:

Grand Hall B

Target Audience:

HTX, BSTR, EEP, PEDS, PHARM

**Chairs:**

Jignesh K. Patel, MD, PhD, and Catherine M. Murks, PhD, APN

**12:00 PM** ( **509)** The Incidence of Donor-Specific Antibody in the Presence of Biopsy-Proven Antibody-Mediated Rejection After Heart Transplantation; __ S. Sana, J. Patel, M. Kittleson, T. Aintablian, M. Rafiei, D. Luthringer, X. Zhang, N. Reinsmoen, L. Czer. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**12:15 PM** ( **510)** Longitudinal Rho-Associated Kinase (ROCK) Activity Correlates with Rejection in Heart Transplant Recipients; __ B. Chung, M. Knapp, D. Rodgers, G. Kim, S. Adatya, N. Sarswat, T. Imamura, E. Karrar, J. Zhou, L. Zhang, G. Sayer, J. Liao, N. Uriel. _Cardiology, University of Chicago, Chicago, IL_

**12:30 PM** ( **511)** Pre-Transplant Donor-Recipient Characteristics and the Relationship to Early Cardiac Allograft Injury Measured by Cell-Free DNA; __ P. Shah1, S. Agbor-Enoh2, A. Ulyanov3, S. Gorham2, U. Fideli2, I. Tunc2, J. Zhu2, M. Jang2, Y. Yang2, K. Bhatti2, A. Marishta2, M. E. Rodrigo4, S. M. Pham5, K. B. Shah6, S. D. Russell7, E. Feller8, H. A. Valantine2. 1 _Heart Failure and Transplantation, Inova Heart and Vascular Institute, Falls Church, VA,_ 2 _Laboratory of Transplantation Genomics, NHLBI, Bethesda, MD,_ 3 _Bioinformatics, Inova Translational Medicine Institute, Falls Church, VA,_ 4 _Heart Failure and Transplantation, Washington Hospital Center, Washington, DC,_ 5 _Cardiothoracic Surgery, University of Maryland, Baltimore, MD,_ 6 _Cardiovascular Medicine, Virginia Commonwealth University, Richmond, VA,_ 7 _Cardiovascular Medicine, Johns Hopkins University, Baltimore, MD,_ 8 _Cardiovascular Medicine, University of Maryland, Baltimore, MD_

**12:45 PM** ( **512)** Identification and Validation of Non-HLA Antibodies in Cardiac Allograft Rejection; __ C. Butler1, N. Jiang2, P. Rao1, Y. Zheng1, D. Gjertson1, Q. Zhang1, M. Cadeiras1, M. Deng1, B. Ray2, E. Reed1. 1 _UCLA, Los Angeles, CA,_ 2 _Immucor, Inc., Stamford, CT_

**1:00 PM** ( **513)** Combined Heart and Liver Transplantation in Highly Sensitized Patients: Protection of the Cardiac Allograft from Antibody Mediated Rejection by Initial Liver Implantation; __ R. C. Daly, N. L. Pereira, T. Taner, M. J. Gandhi, J. K. Heimbach, J. A. Dearani, B. S. Edwards, S. S. Kushwaha. _Mayo Clinic, Rochester, MN_

**1:15 PM** ( **514)** Racial Differences in the Development of De Novo DSA andTreated AMR Following Heart Transplantation; __ R. T. Cole, J. Gandhi, M. Yin, S. R. Laskar, D. Gupta, D. Nguyen, A. Smith, J. D. Vega, A. Morris. _Cardiology, Emory Univ Sch of Med, Atlanta, GA_

12:00 PM - 1:30 PM

## ORAL SESSION 50: Influencing Long-term Outcomes in Lung Transplantation

Location:

Grand Hall C

Target Audience:

LTX, BSTR, ID, NHSAH, PEDS, PHARM

**Chairs:**

Jason D Christie, MD, and Johanna M Kwakkel-van Erp, MD, PhD

**12:00 PM** ( **515)** A Study of QuantiFERON-CMV-Directed CMV Prophylaxis versus Standard-of-Care to Reduce Late CMV Reactivation Following Lung Transplantation; __ G. P. Westall, Y. Cristiano, A. Peleg, M. Paraskeva, B. Levvey, H. Whitford, G. Snell. _Alfred Hospital, Melbourne, Australia_

**12:15 PM** ( **516)** Regulation of KLRG1 Gene Expression by T-bet Correlates with Human Cytomegalovirus-Specific CD8+ T Cells Effector Function; __ A. Hoji1, I. Popescu1, M. Pipeling1, H. Mannem2, J. McDyer1. 1 _UPMC, Pittsburgh, PA,_ 2 _UVA, Charlottesville, VA_

**12:30 PM** ( **517)** Single Nucleotide Polymorphism in a Gene Involved in Mycophenolic Acid Metabolism Is Linked to Survival Post-Lung Transplantation; __ L. K. Tague1, D. Byers1, R. Hachem1, A. Gelman2. 1 _Internal Medicine, Pulmonary and Critical Care Medicine, Washington University in St. Louis, Saint Louis, MO,_ 2 _Cardiothoracic Surgery, Washington University in St. Louis, Saint Louis, MO_

**12:45 PM** ( **518)** Basliximab for CNI Holiday in Lung Transplant Recipients with Acute Kidney Injury; __ U. Goswami1, R. Z. Brown2, K. D. Rudser2, M. I. Hertz1, J. R. Patil1, R. Tomic1, G. Loor3, J. M. Dunitz1. 1 _Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Minnesota, Minneapolis, MN,_ 2 _Biostatistics, University of Minnesota, Minneapolis, MN,_ 3 _Cardiovascular Surgery, University of Minnesota, Minneapolis, MN_

**1:00 PM** ( **519)** Regional Variation in Lung Transplant Outcomes; __ W. M. Whited, J. R. Trivedi, M. P. Fox, V. H. van Berkel. _Department of Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, KY_

**1:15 PM** ( **520)** The Burden of Sinus Disease in Cystic Fibrosis Lung Transplant Recipients; __ L. Morlacchi1, M. Greer2, I. Tudorache3, F. Blasi1, T. Welte2, J. G. Mainz4, J. Gottlieb2. 1 _Department of Pathophysiology and Transplantation, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico di Milano; Università degli Studi di Milano, Milano, Italy,_ 2 _Department of Respiratory Medicine, Lungentransplantation, Medizinische Hochschule Hannover, Hannover, Germany,_ 3 _Department of Cardiothoracic, Transplant and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany,_ 4 _Department of Paediatrics, CF-Center for Children and Adults, Jena University Hospital, Jena, Germany_

12:00 PM - 1:30 PM

## ORAL SESSION 51: Optimizing Outcomes After Heart Transplantation: Predictors and Risk Scores

Location:

Grand Hall D

Target Audience:

HTX, MCS, PATH

**Chairs:**

Shelley A Hall, MD, and George Javorsky, MBBS, FRACP

**12:00 PM** ( **521)** Is the ISHLT-Suggested Inotrope Score a Predictor of In-Hospital Mortality After Heart Transplantation?; __ M. Wright1, K. Takeda1, C. Mauro2, P. Kurlansky1, J. Han1, L. Truby1, M. Salna1, V. Topkara1, A. R. Garan1, M. Yuzefpolskaya1, P. Colombo1, Y. Naka1, M. Farr1, H. Takayama1. 1 _Columbia University Medical Center, New York, NY,_ 2 _Columbia University, Mailman School of Public Health, New York, NY_

**12:15 PM** ( **522)** GIMVECH: A Novel Risk Score for Stroke in the Perioperative Post Transplant Period; __ N. Nair1, S. Yang2, E. Gongora3. 1 _Cardiology, Texas Tech Health Sciences Center, Lubbock, TX,_ 2 _Internal Medicine, Texas Tech Health Sciences Center, Lubbock, TX,_ 3 _Cardiothoracic Surgery, Memorial Cardiac and Vascular Institute, Hollywood, FL_

**12:30 PM** ( **523)** Early Acute Humoral Rejection Does Not Alter Prognosis After Heart Transplantation; __ G. Coutance1, L. Van Aelst1, S. Ouldammar1, P. Rouvier2, S. Saheb3, N. Brechot4, G. Lebreton1, A. Bouglé5, A. Combes4, J. Amour5, P. Leprince1, S. Varnous1. 1 _Thoracic and Cardiovascular Surgery, Groupe Hospitalier Pitié-Salpêtrière, Paris, France,_ 2 _Laboratory of Pathology, Groupe Hospitalier Pitié-Salpêtrière, Paris, France,_ 3 _Hemobiotherapy, Groupe Hospitalier Pitié-Salpêtrière, Paris, France,_ 4 _Medical Intensive Care Unit, Groupe Hospitalier Pitié-Salpêtrière, Paris, France,_ 5 _Anesthesiology and Reanimation, Groupe Hospitalier Pitié-Salpêtrière, Paris, France_

**12:45 PM** ( **524)** Influence of Structurally Based HLA Mismatching on Long-Term Graft Loss in Adult Heart Transplant Recipients; __ J. Nilsson1, A. Nilsson1, V. Jernryd1, M. Ohlsson2, B. Andersson3. 1 _Cardiothoracic Surgery, Lund University and Skane University Hospital, Lund, Sweden,_ 2 _Computational Biology and Biological Physics, Lund University, Lund, Sweden,_ 3 _Surgery, Lund University and Skane University Hospital, Lund, Sweden_

**1:00 PM** ( **525)** Consequence of Retained Defibrillator and Pacemaker Leads Following Heart Transplantation - An Under-Sensed Problem?; __ L. Holzhauser, T. Imamura, A. Nguyen, B. Chung, T. Ota, S. Adatya, G. Kim, G. Sayer, N. Sarswat, J. Raikhelkar, V. Jeevanandam, N. Uriel. _Cardiology, University of Chicago, Chicago, IL_

**1:15 PM** ( **526)** High-Risk and Low-Risk Donor/Recipient Characteristics and 90-Day Transplant Outcomes in LVAD versus Standard Recipients; __ M. Urban, N. Robinson-Smith, A. Woods, S. Schueler, G. Parry, G. MacGowan. _Freeman Hospital, Newcastle upon Tyne, United Kingdom_

12:00 PM - 1:30 PM

## ORAL SESSION 52: Does Size Matter? Center Volume, Urgency Status and Managing Complications

Location:

Seaport F-H

Target Audience:

EEP, HF, HTX, LTX, MCS, NHSAH, PEDS, PHARM

**Chairs:**

Axel Rahmel, MD, and Jonathan P Singer, MD, MS

**1:15 PM** ( **527)** Benefits of Specialized Thoracic Adapted Recovery (STAR) Team Model for Heart and Lung Transplantation; __ H. A. Tetteh1, P. Brandenhoff2, R. S. Higgins3. 1 _Department of Surgery, Uniformed Services University, Bethesda, MD,_ 2 _Department of Surgery, University of California San Francisco, San Francisco, CA,_ 3 _Department of Surgery, Johns Hopkins University, Baltimore, MD_

**12:15 PM** ( **528)** Should Heart Transplantation in High Risk Recipients Be Performed in High Volume Centers?; __ C. Legeai1, O. Bastien1, C. Jasseron1, C. Cantrelle1, S. Varnous2, L. Sebbag3, A. Belin4, R. Dorent1. 1 _Agence de la Biomédecine, Saint-Denis, France,_ 2 _Hôpital Pitié-Salpêtrière, Paris, France,_ 3 _CHU Lyon, Lyon, France,_ 4 _CHU Caen, Caen, France_

**12:30 PM** ( **529)** Effect of Broader Geographic Sharing of Donor Lungs on Regional Waitlist (WL) Mortality and Transplant Center Volume; __ J. Mooney1, L. Chhatwani1, J. Boyd2, G. S. Dhillon1. 1 _Medicine, Stanford University School of Medicine, Stanford, CA,_ 2 _Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA_

**12:45 PM** ( **530)** Use of Urgent Statuses to List Adult Heart Transplant Candidates Is Increasing; __ W. Parker1, M. Churpek1, S. Fedson2, E. Garrity1. 1 _Pulmonary and Critical Care, University of Chicago Medicine, Chicago, IL,_ 2 _Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX_

**1:00 PM** ( **531)** Impact of Surgical Bleeding on the Cost of Hospitalization for Left-Ventricular Assist Device Implantation; __ K. Lietz1, C. Barreiro1, J. Philpott1, C. Flink2, M. McGrath1, J. Herre1. 1 _Division of Advanced Heart Failure, Sentara Heart Hospital, Norfolk, VA,_ 2 _Cardiovascular Research Institute, Norfolk, VA_

**12:00 PM** ( **532)** The Impact of Center VAD Operative Volumes on Outcomes After VAD Implant; __ J. A. Cowger1, J. M. Stulak2, P. Shah3, T. F. Dardas4, F. D. Pagani5, S. M. Dunlay6, K. D. Aaronson7, R. Singh8, N. A. Mokadam9, S. Maltais10, J. K. Kirklin11, C. T. Salerno12. 1 _Cardiovascular Medicine, St. Vincent Heart Center of Indiana, Indianapolis, IN,_ 2 _Surgery, Mayo Clinic, Rochester, MN,_ 3 _Cardiovascular Medicine, Inova Heart & Vascular Institute, Fairfax, VA, _4 _Cardiovascular Medicine, University of Washington, Seattle, WA,_ 5 _Cardiac Surgery, University of Michigan, Ann Arbor, MI,_ 6 _Cardiovascular Medicine, Mayo Clinic, Rochester, MN,_ 7 _Cardiovascular Medicine, University of Michigan, Ann Arbor, MI,_ 8 _Cardiovascular Medicine, Inova Heart & Vascular Institute, Falls Church, VA, _9 _Cardiovascular Surgery, University of Washington, Seattle, WA,_ 10 _Cardiac Surgery, Mayo Clinic, Rochester, MN,_ 11 _Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL,_ 12 _Surgery, St. Vincent Heart Center of Indiana, Indianapolis, IN_

12:00 PM - 1:30 PM

## ORAL SESSION 53: Getting to the Heart of the Matter: Psychosocial Factors Predict Outcomes in Transplant and MCS

Location:

Coronado A-C

Target Audience:

NHSAH, ALL

**Chairs:**

Karen C. Uzark, PhD, PNP, and Kevin C Carney, MSN, CRNP, CCTC

(533) WITHDRAWN

**12:00 PM** ( **243)** Social and Clinical Characteristics Associated with Increased Short Term Mortality in Non-Inotrope Dependent Patients Undergoing Left Ventricular Assist Device Therapy: Results from InterMACS; __ S. M. Joseph1, R. L. Kormos2, J. Teuteberg3, A. Althouse4, J. Cowger5. 1 _Baylor University Medical Center, Dallas, TX,_ 2 _Surgery, University of Pittsburgh, Pittsburgh, PA,_ 3 _Interneal Medicine, University of Pittsburgh, Pittsburgh, PA,_ 4 _University of Pittsburgh, Pittsburgh, PA,_ 5 _St Vincent Medical Center, Indianapolis, IN_

**12:15 PM** ( **534)** Depressive Symptoms and Post-Transplant Mortality: Examining the Influence of Perioperative Outcomes; __ P. J. Smith, S. M. Palmer, L. D. Snyder, B. M. Hoffman, K. K. Ingle, G. L. Stonerock, C. Saulino, J. A. Blumenthal. _Duke University Medical Center, Durham, NC_

**12:30 PM** ( **535)** Social Desirability Response Bias in Transplant Candidates' Self-Report of Psychosocial Variables; __ G. L. Stonerock, P. J. Smith, B. M. Hoffman, K. K. Ingle, C. K. Saulino, J. A. Blumenthal. _Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC_

**12:45 PM** ( **536)** The Impact of Pre-LVAD Psychosocial Evaluations on Post-LVAD Outcomes; __ M. Sobhanian, M. Converse, N. Patel, A. Mardis, D. Taber, B. Houston, B. Ramu, E. Serber, A. Agyemang, D. Heyward, W. Uber, H. Meadows. _Medical University of South Carolina, Charleston, SC_

**1:00 PM** ( **537)** Cognitive Function: A Significant Predictor of Quality of Life in Adults with an Implantable Ventricular Assist Device; __ J. M. Casida1, J. J. Yang1, H. Craddock2, P. Combs3. 1 _School of Nursing, University of Michigan, Ann Arbor, MI,_ 2 _Heart Failure/Mechanical Circulatory Support, Washington University, Saint Louis, MO,_ 3 _VAD/Heart Failure, Jewish Hospital, Louisville, KY_

**1:15 PM** ( **538)** Individual and Dyad Determinants of Patient Quality of Life and Caregiver Strain in Ventricular Assist Device Therapy; __ J. T. Bidwell1, J. O. Mudd2, K. S. Lyons3, K. L. Grady4, J. M. Gelow2, S. O. Hiatt3, C. V. Chien2, C. S. Lee3. 1 _Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA,_ 2 _Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, _3 _School of Nursing, Oregon Health & Science University, Portland, OR, _4 _Feinberg School of Medicine, Northwestern University, Chicago, IL_

# Poster Session 1

Wednesday, April 05, 2017

6:15 PM - 7:15 PM

NOTE: Poster presenters and discussants will be present during the evening poster viewing session from 6:15 PM – 7:15 PM.

## Heart Failure

(Seaport Foyer)

**Poster Discussants:** Richa Agarwal, MD (USA), Maria Crespo-Leiro, MD (Spain), Savitri Fedson, MD (USA), Robert Gordon, MD (USA), George Javorsky, MBBS, FRACP (Australia), Catherine Murks, PhD, APN (USA), Sunu Thomas, MD (USA)

**(539)** Racial Differences in Receipt of Care by a Cardiologist During a Critical Heart Failure Admission; __ K. Breathett1, W. G. Liu2, L. A. Allen1, S. L. Daugherty1, I. V. Blair3, J. Jones4, G. K. Grunwald2, M. Moss5, T. H. Kiser5, E. Burnham5, R. W. Vandivier5, B. Clark5, E. F. Lewis6, S. Mazimba7, P. M. Ho8, P. Peterson9. 1 _Division of Cardiology, University of Colorado, Aurora, CO,_ 2 _Veteran Affairs Eastern Colorado Health Care System, Denver, CO,_ 3 _Division of Psychology and Neuroscience, University of Colorado, Boulder, CO,_ 4 _Department of Nursing, University of Colorado, Aurora, CO,_ 5 _Division of Pulmonary Sciences and Critical Care, University of Colorado, Aurora, CO,_ 6 _Division of Cardiology, Brigham and Women's Hospital, Boston, MA,_ 7 _Division of Cardiology, University of Virginia Health System, Charlottesville, VA,_ 8 _Division of Cardiology, University of Colorado and Veteran Affairs Eastern Colorado Health Care System, Aurora, CO,_ 9 _Division of Cardiology, University of Colorado and Denver Health Medical Center, Aurora, CO_

**(540)** Risk Factors Associated with Mortality in Broad HF Population; __ D. Weisshaar1, D. Lin2, L. Tucker3, J. Trammell1. 1 _Heart Transplant, Kaiser Permanente Northern California, Santa Clara, CA,_ 2 _Graduate Medical Education, Kaiser Permanente Northern California, Santa Clara, CA,_ 3 _Division of Research, Kaiser Permanente Northern California, Oakland, CA_

**(541)** The REVIVAL Registry of Ambulatory Advanced Heart Failure: Baseline Characteristics; __ M. Palardy1, R. McLean2, S. Pamboukian3, M. M. Kittleson4, L. Warner Stevenson5, P. Shah6, G. Ewald7, S. Russell8, S. Robinson9, U. Jorde10, N. Jeffries11, C. Spino12, J. Baldwin13, D. L. Mann14, G. C. Stewart5, K. Aaronson1, F. REVIVAL Investigators1. 1 _University of Michigan, Ann Arbor, MI,_ 2 _University of Pennsylvania, Philadelphia, PA,_ 3 _University of Alabama at Birmingham, Birmingham, AL,_ 4 _Cedars-Sinai Heart Institute, Beverly Hills, CA,_ 5 _Brigham and Women's Hospital, Boston, MA,_ 6 _Inova Heart and Vascular Institute, Falls Church, VA,_ 7 _Washington University School of Medicine, St. Louis, MO,_ 8 _The Johns Hopkins University School of Medicine, Baltimore, MD,_ 9 _University of Maryland, College Park, MD,_ 10 _Montefiore Medical Center, Bronx, NY,_ 11 _National Heart, Lung and Blood Institute, Bethesda, MD,_ 12 _Biostatistics Department, University of Michigan, Ann Arbor, MI,_ 13 _National Heart, Lung, and Blood Institute, Bethesda, MD,_ 14 _Washington University, St. Louis, MO_

**(542)** Impact of Preoperative Extracorporeal Membrane Oxygenation Apply on Heart Transplantation; __ S. Lee, Y. Youn, H. Joo, J. Kim. _Severance Cardiovacular Hospital, Seoul, Korea, Republic of_

**(543)** Impact of a Comprehensive Heart Failure Self-Care Review; __ G. Mentzer1, K. Packard2, R. Holcomb3, J. Stachura4, S. Lawler1, G. Montoya5, A. Wardyn6. 1 _Cardiovascular, Nebraska Heart Institute, Lincoln, NE,_ 2 _Pharmacy, Creighton University, Omaha, NE,_ 3 _Cardiovascular Research, Nebraska Heart Institute, Lincoln, NE,_ 4 _Cardiovascular, CHI Health St. Elizabeth, Lincoln, NE,_ 5 _Pharmacy, Creighton University, Lincoln, NE,_ 6 _Wesleyan University, Lincoln, NE_

**(544)** Marital Status Predicts Hospital Length of Stay in Patients with Congestive Heart Failure Exacerbation; __ V. Kataria, N. Yamani, M. Alimohamed, A. Silver, N. Saha, B. Mohamedali. _Rush University Medical Center, Chicago, IL_

**(545)** First Results of the Territorial Organization in the Attention to Cardiogenic Shock; __ F. J. Hernandez-Perez, J. Segovia, M. Gomez-Bueno, J. Goirigolzarri, J. M. Escudier, A. Forteza, J. M. Alvarez, L. Alonso-Pulpon. _Hospital Universitario Puerta De Hierro Madrid Spain, Madrid, Spain_

**(546)** High-Risk Heart Failure Patients Can Be Successfully Identified by an Automated Search Algorithm Using Electronic Health Records; __ S. Emani1, R. Buchanan2, S. Zaidi3, D. Selsky4, A. M. Lai5. 1 _Division of Cardiology, Ohio State University, Columbus, OH,_ 2 _Gevity, Inc, Toronto, ON, Canada,_ 3 _Gevity, Inc., Toronto, ON, Canada,_ 4 _Capsenta, Austin, TX,_ 5 _Institute for Informatics, Washington University in St. Louis, St. Louis, MO_

**(547)** Trends in Palliative Care in Inpatient Advanced Heart Failure After Initiation of a Dedicated Palliative Care Team; __ M. A. Chandrasekhar1, S. Mohammad2, K. Walker2, G. Ruiz2, H. Groninger2. 1 _Internal Medicine, Medstar Washington Hospital Center, Washington, DC,_ 2 _Medstar Washington Hospital Center, Washington, DC_

**(548)** The Age Paradox in Survival Among Patients with Systolic Heart Failure on 'Destination' Inotropic Therapy; __ G. G. Sokos, K. Cherukuri, R. Agarwal, A. Raina. _Cardiovascular Institute, Allegheny General Hospital, Pittsburgh, PA_

**(549)** Noninvasive Assessment of Lung Fluid Percentage in Advanced Heart Failure Patients; __ S. Adatya1, T. Imamura1, G. H. Kim1, G. Sayer1, D. Rodgers1, J. Raikhelkar1, A. Nguyen1, B. Chung1, N. Sarswat1, R. Abbo2, D. Burkhoff3, N. Uriel1. 1 _University of Chicago, Chicago, IL,_ 2 _Sensible Medical, Netanya, Israel,_ 3 _Department of Medicine, Columbia University, New York, NY_

**(550)** Implementation of an Informed Consent Process for Advanced Heart Failure Therapies: Defining the Population and Process; __ C. H. Fine1, J. Gelow2, J. Davis2, J. Mudd2, V. Herbl2. 1 _Internal Medicine, Oregon Health and Science, Portland, OR,_ 2 _Knight Cardiovascular Institute, Oregon Health and Science, Portland, OR_

**(552)** Levosimendan in Heart Failure with Preserved Systolic Function; __ J. Goirigolzarri, J. Vazquez Lopez-Ibor, F. J. Hernandez, M. Gomez-Bueno, J. M. Solano-Lopez, D. Jimenez, L. Alonso-Pulpon, J. Segovia. _Hospital Universitario Puerta De Hierro Madrid Spain, Madrid, Spain_

**(553)** WITHDRAWN

**(554)** Treatment with Sacubitril/Valsartan Regarding Evaluation for Heart Transplantation; __ F. M. Strangl, M. Rybczinski. _Klinik für Allgemeine und Interventionelle Kardiologie, Universitäres Herzzentrum Hamburg, Hamburg, Germany_

**(555)** Right Internal Jugular Access Is an Alternative to Femoral Access for CardioMEMS Implantation; __ R. S. Lewis1, L. Wang2, K. J. Spinelli3, J. D. Remick1, J. Paulson4, J. Chappell4, J. Abraham1. 1 _Center for Advanced Heart Disease, Providence Heart and Vascular Institute, Portland, OR,_ 2 _Medical Data Research Center, Providence Heart and Services, Portland, OR,_ 3 _Regional Research Center, Providence Heart and Services, Portland, OR,_ 4 _McKenzie Heart, Lung and Vascular Center, McKenzie-Willamette Medical Center, Springfield, OR_

**(556)** Heart Transplantation or Mechanical Circulatory Support May Be Safely Deferred for Two Years in Patients with Suppressed Natriuretic Peptide Levels; __ G. Whittaker1, A. Kydd2, C. Lewis2, J. Parameshwar2, S. J. Pettit2. 1 _School of Medical Education, King's College London, London, United Kingdom,_ 2 _Transplant Unit, Papworth Hospital NHS Foundation Trust, Cambridge, United Kingdom_

**(557)** Baseline Hemodynamic Indices of Mixed Pulmonary Hypertension Do Not Predict Pressure Reduction in Patients with Chronic Heart Failure Implanted with CardioMEMS HF Sensor; __ A. M. Wolfson1, L. Saxon1, L. Grazette1, H. Nazeer2, D. Shavelle1, R. Jermyn2. 1 _Cardiology, University of Southern California, Los Angeles, CA,_ 2 _Cardiology, Hofstra School of Medicine at Northwell Health, Hampstead, NY_

**(558)** Worsening Renal Function in Patients with Low Output Decompensated Heart Failure Is Associated with 1-Year Mortality; __ J. Tsay, B. Lampert, B. Whitson, R. Hasson, R. Emani, A. Hasan, A. Kilic, S. Smith. _The Ohio State University, Columbus, OH_

**(559)** Clinical Risk Factors of Advanced Systolic Heart Failure in Hypertrophic Cardiomyopathy; __ S. J. Lee, K. H. Kim, H. J. Jang, S. K. Hong. _Cardiology, Sejong General Hospital, Bucheon, Korea, Republic of_

**(560)** Frailty Does Not Increase The Risk of Adverse Outcomes Following a Hospitalization for Heart Failure Decompensation; __ J. G. Duero Posada1, H. Baranek2, C. Pendrith2, M. McDonald1, H. Ross1, S. Bhatia3. 1 _Cardiology, University Health Network, Toronto, ON, Canada,_ 2 _Institute for Health System's Solutions and Virtual Care, Women's College Hospital, Toronto, ON, Canada,_ 3 _Cardiology, Women's College Hospital, Toronto, ON, Canada_

**(561)** Predictors of Survival in Patients with Cardiac Amyloidosis; __ Y. Moayedi1, J. P. Duero1, F. Foroutan2, A. C. Alba1, H. J. Ross1, D. Delgado1. 1 _Medicine, University of Toronto, Toronto, ON, Canada,_ 2 _Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada_

**(562)** Nutritional Characteristics of Patient with Chagas Cardiomyopathy with Decompensated Heart Failure; __ L. C. Tavares1, H. F. Moreira1, C. B. Terhoch1, S. H. Lage2, M. T. Oliveira Junior3, E. A. Bocchi1, V. S. Issa1. 1 _Department of Heart Failure, Heart Institute (InCor) do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil,_ 2 _Department of Cardiopneumology, Heart Institute (InCor) do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil,_ 3 _Emergency Unit, Heart Institute (InCor) do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil_

**(563)** Does Heart Failure with a Lower Ejection Fraction Mean Higher Costs? Insights from Data Analytics Across a Large Health Care System; __ C. B. Link1, S. Koscumb2, P. Lynch2, R. Ramani1, M. Shullo1, O. Marroquin1, J. J. Teuteberg1. 1 _HVI, UPMC, Pittsburgh, PA,_ 2 _Department of Clinical Analytics, UPMC, Pittsburgh, PA_

**(564)** Outcomes and Characteristics of Patients with Critical Cardiogenic Shock Admitted to a Quaternary Heart Failure Unit in the UK; __ P. S. Chaggar1, E. McKay1, P. Foden2, S. G. Williams1, J. Barnard1, N. Yonan1, R. Venkateswaran1, S. M. Shaw1. 1 _The Transplant Unit, University Hospital of South Manchester, Manchester, United Kingdom,_ 2 _Medical Statistics, University Hospital of South Manchester, Manchester, United Kingdom_

**(565)** Peak Oxygen Consumption as a Prognostic Marker in Patients with Cardiac Amyloidosis; Y. Moayedi1, J. G. Duero Posada1, D. H. Delgado1, F. Foroutan2, T. Schofield1, H. J. Ross1, A. C. Alba1 _._ 1 _Medicine, University of Toronto, Toronto, ON, Canada,_ 2 _Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada_

**(566)** Predictors of Survival in Critical Cardiogenic Shock Admissions to a Quaternary Heart Failure Unit in the UK; __ P. M. Chaggar, E. McKay, S. G. Williams, J. Barnard, N. Yonan, R. Venkateswaran, S. M. Shaw. _The Transplant Unit, University Hospital of South Manchester, Manchester, United Kingdom_

**(567)** Frequency of Recovery and Relapse in Patients with Nonischemic Dilated Cardiomyopathy on Medical Therapy; __ K. Kim, S. Lee, S. Hong. _Sejong General Hospital, Bucheon, Korea, Republic of_

**(568)** Metabolomic Differences Between Patients with Advanced Heart Failure and Healthy Controls; __ B. Lima, E. Arning, C. Harmon, J. Felius, S. M. Joseph, G. V. Gonzalez-Stawinski, S. A. Hall, T. Bottiglieri. _Baylor University Medical Center, Dallas, TX_

**(569)** Peak Exercise Oxygen Consumption in Patients Hospitalized with Severe and Recurrent Heart Failure: Insights from ESCAPE; __ D. Cheeran1, M. Drazner1, W. Tang2, J. Grodin1. 1 _Cardiology, UT Southwestern, Dallas, TX,_ 2 _Cardiology, Cleveland Clinic, Cleveland, OH_

**(570)** Utilizing Data Analytics to Identify Patients at Highest Risk of Heart Failure Readmission; __ C. B. Link1, S. Koscumb2, P. Lynch2, R. Ramani1, M. A. Shullo1, O. Marroquin1, J. J. Teuteberg1. 1 _HVI, UPMC, Pittsburgh, PA,_ 2 _Department of Clinical Analytics, UPMC, Pittsburgh, PA_

**(571)** The Mortality of Cardiogenic Shock in Patients Admitted with Acute Decompensated Systolic Heart Failure; __ J. Kumar, C. Dillane, J. Plamenac, D. Schwartz. _Temple University Hospital, Philadelphia, PA_

**(572)** Endothelial Dysfunction in Heart Failure; __ A. Ali, R. Araujo-Gutierrez, A. S. Cruz-Solbes, C. Uribe, K. A. Youker, A. Bhimaraj. _DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, TX_

## Heart Transplantation

(Seaport Foyer)

**Poster Discussants:** Sean Agbor-Enoh, MD (USA), Robert J Chen, MD, MPH (Taipei), Vlad Cotarlan, MD (USA), Jill C Krisl, PharmD (USA), Bruno M Meiser, MD (Germany), Sanem Nalbantgil, MD (Turkey), Susan Woodley Restaino, MD (USA), Veli K Topkara, MD (USA)

**(573)** Normothermic Ex Vivo Heart Perfusion in Argentina; __ I. G. Berra1, S. Berra2, M. L. Berra3, A. Irusta4, M. A. Lewis5. 1 _Heart Transplant Department, Hospital Garrahan Argentina, Buenos Aires, Argentina,_ 2 _Control Department - Facultad de Ingenieria, Universidad de Buenos Aires, Buenos Aires, Argentina,_ 3 _Clinical Department, Hospital Posadas Argentina, Buenos Aires, Argentina,_ 4 _Biomaterials, Lew Supplies and Innovations, Buenos Aires, Argentina,_ 5 _Medical Research, Lew Supplies and Innovations, Buenos Aires, Argentina_

**(574)** Acute Cellular Rejection (ACR) ± Antibody Mediated Rejection (AMR) - Double Trouble or Overrated?; __ J. Goekler, A. Zuckermann, E. Osorio, K. Uyanik-Uenal, G. Laufer, A. Aliabadi-Zuckermann. _Medical University Vienna, Vienna, Austria_

**(575)** Cytomegalovirus Infection and Rejection May Cause Myocardial Tissue Alterations Detectable at Cardiac Magnetic Resonance at One Year Follow-Up After Heart Transplant; __ P. Pedrotti1, P. Campadello1, G. Masciocco1, R. Facchetti2, A. Milazzo1, G. Quattrocchi1, M. P. Gagliardone1, C. F. Russo1, C. Giannattasio1, M. Frigerio1. 1 _Dipartimento Cardiotoracovascolare A. De Gasperis, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy,_ 2 _Dipartimento di Medicina Clinica e Prevenzione, Università degli Studi Milano Bicocca, Milan, Italy_

**(576)** Severe Tricuspid Regurgitation After Heart Transplantation: Does It Require Surgical Repair?; __ D. Geft, M. Kittleson, J. Patel, T. Aintablian, K. Yabuno, B. Kearney, E. Kransdorf, D. H. Chang, L. Czer, A. Trento, J. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(577)** Stratifying MELD-XI by Cardiomyopathy; __ E. Adams, N. J. Jackson, A. Iyengar, L. C. Reardon. _David Geffen School of Medicine, UCLA, Los Angeles, CA_

**(578)** Factor VIIa Administration in Cardiothoracic Transplant and Its Impact on Thromboembolic Events and Post-Transplant Outcomes; __ R. Winstead1, K. Pandya1, J. Flynn1, G. Davis1, A. Sieg1, M. Guglin1, G. Klink2, R. Evans1. 1 _University of Kentucky Healthcare, Lexington, KY,_ 2 _University of Kentucky College of Pharmacy, Lexington, KY_

**(579)** WITHDRAWN

**(580)** Changes and Relationship Between Invasive Hemodynamic and Brain Natriuretic Peptide During the Early to Late Phase of First Year After Heart Transplantation; __ T. S. Clemmensen, H. Eiskjær, B. B. Løgstrup, S. H. Poulsen. _Department of Cardiology, Aarhus University Hospital, Skejby, Denmark, Aarhus N, Denmark_

**(581)** Bridge-to-Transplant LVAD or Primary Heart Transplantation in Young Patients? Both Offer Similar Mid-Term Survival; __ M. James, K. Takeda, P. Kurlansky, M. Ando, C. Lee, J. Han, M. Wright, V. Topkara, A. R. Garan, M. Yuzefpolskaya, M. Farr, P. Colombo, Y. Naka, H. Takayama. _Columbia University Medical Center, New York, NY_

**(582)** Results of Adult Heart Transplant While Supported on Extra-Corporeal Membrane Oxygenator Support: Evidence from a National Registry; __ S. Deo1, M. Zacharias2, R. Benatti2, M. Robinson2, C. Elamm3, B. Sareyyupoglu1, B. Medalion1, Y. Elgudin1, G. Oliveira2, S. Park1, M. Ginwalla2. 1 _Cardiac Surgery, University Hospitals, Cleveland, OH,_ 2 _Cardiology, University Hospitals, Cleveland, OH,_ 3 _Cardio, University Hospitals, Cleveland, OH_

**(583)** Cardiogenic Shock in Peripartum Cardiomyopathy: How to Succeed without Long-Term Left Ventricular Assist Device? Experience of Argentinean Center; __ M. A. Peradejordi, L. E. Favaloro, R. D. Ratto, M. M. López Rosetti, M. F. Renedo, A. L. Guazzone, D. O. Absi, R. R. Favaloro, A. M. Bertolotti. _Intrathoracic Transplantation and Heart Failure Division, Favaloro Foundation - University Hospital, Buenos Aires, Argentina_

**(584)** Pre- and Post-Transplant Renal Dysfunction in Cardiac Transplant Recipients: A Retrospective Single Center Analysis; __ K. L. Freystaetter1, G. A. Bohmig2, A. Aliabadi-Zuckermann1, A. Kaider3, R. Moayedifar1, E. Osorio1, K. Uyanik-Uenal1, G. Laufer1, A. Zuckermann1. 1 _Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria,_ 2 _Division of Nephrology and Dialysis, Department of Medicine III,, Medical University of Vienna, Vienna, Austria,_ 3 _Center for Medical Statistics, Informatics and Intelligent Systems, Section for Clinical Biometrics, Medical University of Vienna, Vienna, Austria_

**(585)** Does a History of Malignancy Affect Long-Term Survival in Heart Transplant Recipients?; __ Y. Ravi1, E. M. Stock2, S. K. Lella3, J. V. Balasubramaniyan4, L. A. Nikloidis5, L. M. Copeland6, S. Emani7, C. B. Sai-Sudhakar1. 1 _Cardiac Surgery, Scott & White, Texas A&M, Temple, TX, _2 _Center for Applied Health Research, Veterans Health System, Perry Point, MD,_ 3 _College of Medicine, Scott & White, Texas A&M, Temple, TX, _4 _Cardiology, Sri Ramachandra University, Chennai, India,_ 5 _Internal Medicine, Scott & White, Texas A&M, Temple, TX, _6 _Center for Applied Health Research, Scott & White, Texas A&M, Temple, TX, _7 _Internal Medicine, The Ohio State University, Columbus, OH_

**(586)** Improved Quality, Increased Volume, and Better Outcomes Using a Specialized Thoracic Adapted Recovery (STAR) Model for Heart Transplantation; __ H. A. Tetteh1, E. J. Molina2, J. M. Block2, C. C. Shults2. 1 _Department of Surgery, Uniformed Services University, Bethesda, MD,_ 2 _MedStar Heart Institute, MedStar Washington Hospital Center, Washington, DC_

**(587)** L-Arginine and Methylarginines Prior to and After Heart Transplantation; __ J. Lundgren1, A. Sandqvist2, M. Hedeland3, U. Bondesson3, G. Wikström4, G. Rådegran1. 1 _Cardiology, Clinical Sciences, Lund University, Sweden,_ 2 _Pharmacology and Clinical Neuroscience, Clinical Pharmacology, Umeå University, Sweden,_ 3 _Chemistry, National Veterinary Institute Uppsala, Sweden,_ 4 _Medical Sciences, Cardiology, Uppsala University, Sweden_

**(588)** VA ECMO as a Bridge to Transplantation: Emergent Eligibility and Outcomes; __ M. V. Habal, A. R. Garan, V. K. Topkara, K. Takeda, F. Latif, S. Restaino, M. Yuzefpolskaya, R. Bijou, P. Colombo, H. Takayama, Y. Naka, M. Farr. _Columbia University, New York, NY_

**(589)** Clinical Usefulness of Cardiac Magnetic Resonance Imaging After Heart Transplantation; __ G. Poglajen1, A. Cerar1, R. Zbacnik2, G. Zemljič1, S. Frljak1, J. Ksela3, I. Knezevic3, P. Berden2, B. Vrtovec1. 1 _Advanced Heart Failure and Transplantation Programme, Dept. of Cardiology, University Medical Center Ljubljana, Ljubljana, Slovenia,_ 2 _Institute of Radiology, University Medical Center Ljubljana, Ljubljana, Slovenia,_ 3 _Dept. of Cardiovascular Surgery, University Medical Center Ljubljana, Ljubljana, Slovenia_

**(590)** Clinical Outcome and Hemodynamic Function Following the Use of Size-Mismatched Donor Hearts for Orthotopic Heart Transplantation; __ A. A. Ali1, W. Watson1, N. Nwaejike2, A. Page1, J. Schroder2, C. Milano2. 1 _Cardiothoracic Surgery, Papworth Hospital, Cambridge, United Kingdom,_ 2 _Cardiothoracic Surgery, Duke University Medical Center, Durham, NC_

**(591)** De Novo Donor Specific Antibodies (dnDSA) Is Associated with Cardiac Allograft Hypertrophy After Heart Transplantation (HT); __ N. L. Pereira, M. Jesus Valero, M. Wong, S. Kushwaha, B. Smith, W. Kremers, M. Gandhi, D. Richard. _Mayo Clinic, Rochester, MN_

**(592)** Very Long-Term Outcomes of Combined Heart-Lung Transplantation: A Single-Center 26-Year Experience and Current Strategies for Follow-Up; __ V. J. Gonzalez1, E. G. Jernigan1, P. D. Strassle1, J. S. Nelson2. 1 _University of North Carolina at Chapel Hill, Chapel Hill, NC,_ 2 _Cardiothoracic Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC_

**(593)** Success for Combined Heart and Kidney Transplantation; __ D. Megna, F. Esmailian, J. Patel, M. Kittleson, T. Aintablian, E. Stimpson, E. Kransdorf, D. Geft, D. H. Chang, L. Czer, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(594)** Influence of the MELD-XI (Model of End-Stage Liver Disease Excluding INR) on Heart Transplant Outcomes; __ A. Loforte1, M. Gremolini1, M. Cefarelli1, G. Jafrancesco1, E. Pilato1, L. Potena2, M. Masetti2, F. Grigioni2, G. Marinelli1. 1 _Cardiovascular Surgery and Transplantation, S. Orsola-Malpighi Hospital, Bologna University, Bologna, Italy,_ 2 _Cardiology and Transplantation, S. Orsola-Malpighi Hospital, Bologna University, Bologna, Italy_

**(595)** Influence of Pulmonary Vascular Resistance and Pulmonary Elastance on Postoperative Recovery Parameters After Heart Transplant an Analysis of 88 Cases; __ B. Komarakshi1, R. Ratnagiri2, K. Suresh Rao3, M. Tanguturu4. 1 _Cardiac Surgery, Fortis Malar Hospital, Chennai, India,_ 2 _Cardiology, Fortis Malar Hospital, Chennai, India,_ 3 _Cardiac Anesthesia & Criticaal Care, Fortis Malar Hospital, Chennai, India, _4 _Cardiac Anesthesia & Critical Care, Fortis Malar Hospital, Chennai, India_

**(596)** The Variance and Interplay Between Estimated Glomerular Filtration Rate Calculators and the Risk of Adverse Renal Outcomes After Heart Transplantation; __ M. Kahanda1, H. Shah1, E. Novak2, J. Shuster2, S. LaRue2, J. Schilling1. 1 _Internal Medicine, Barnes Jewish Hospital/Washington University in St. Louis, St. Louis, MO,_ 2 _Cardiology, Barnes Jewish Hospital/Washington University in St. Louis, St. Louis, MO_

**(597)** Diagnostic of Acute Heart Transplant Rejection by Means of Speckle-Tracking Echocardiography; __ T. V. Stavenchuk1, E. D. Kosmachova2, I. A. Shelestova2, K. O. Barbuhatty2, V. A. Porhanov2. 1 _Ultrasound Diagnostic, Regional Clinical Hospital n.a. professor S.V. Ochapovsky, Krasnodar, Russian Federation,_ 2 _Regional Clinical Hospital n.a. professor S.V. Ochapovsky, Krasnodar, Russian Federation_

**(598)** The Impact of Race on Hemodynamics and Heart Transplant Outcomes; __ B. A. Smith1, N. Bassi1, C. Wright2, S. Kalantari-Tannenbaum1, J. Grinstein1, G. Kim1, G. Sayer1, S. Adatya1, N. Sarswat1, S. Fedson1, T. Ota3, V. Jeevanandam1, N. Uriel1. 1 _Division of Cardiology, University of Chicago, Chicago, IL,_ 2 _Internal Medicine, University of Pennsylvania, Philadelphia, IL,_ 3 _Cardiac Surgery, University of Chicago, Chicago, IL_

**(599)** Peak Exercise Oxygen Consumption and Heart Transplantation Outcomes; __ B. P. Dhakal, S. G. Al-Kindi, C. M. Bianco, M. Ginwalla, M. R. Robinson, G. Oliveira, C. ElAmm. _Cardiology, Heart Failure and Transplant Division, University Hospitals Cleveland Medical Center, Cleveland, OH_

**(600)** Pulmonary Vascular Resistance Is Not an Independent Predictor of Post-Transplant Outcome in Bridge-to-Transplant Patients; It's Time to Re-Evaluate Our Current Heart Transplant Eligibility; __ M. Ando, K. Takeda, P. A. Kurlansky, M. Wright, C. Lee, J. Han, A. R. Garan, V. K. Topkara, M. Yuzefpolskaya, P. C. Colombo, M. Farr, Y. Naka, H. Takayama. _Columbia University Medical Center, New York, NY_

**(601)** Impact of Pre-Transplant Pulmonary Hypertension Grading on Early- to Long-Term Hemodynamics, Right Venticular Graft Function and Survival After Heart Transplantation; __ A. Loforte1, G. Barberio1, G. Jafrancesco1, M. Cefarelli1, C. Mariani1, L. Potena2, M. Masetti2, A. Russo2, S. Martin Suarez1, F. Grigioni2, G. Marinelli1. 1 _Cardiovascular Surgery and Transplantation, S. Orsola-Malpighi Hospital, Bologna University, Bologna, Italy,_ 2 _Cardiology and Transplantation, S. Orsola-Malpighi Hospital, Bologna University, Bologna, Italy_

**(602)** Incidence of Chronic Renal Dysfunction Prior to Cardiac Transplantation: A Retrospective Single Center Analysis; __ K. L. Freystaetter1, G. A. Bohmig2, A. Aliabadi-Zuckermann1, R. Moayedifar1, E. Osorio1, K. Uyanik-Uenal1, G. Laufer1, A. Zuckermann1. 1 _Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria,_ 2 _Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria_

**(603)** Ablation of Supraventricular Arrhythmias Post Orthotopic Heart Transplantation: Implication of Electro-Anatomical Mapping; __ M. F. Renedo, M. A. Peradejordi, L. E. Favaloro, R. D. Ratto, M. M. López Rosetti, A. L. Guazzone, C. D´amico, N. Galizio, J. L. González, D. O. Absi, R. R. Favaloro, A. M. Bertolotti. _Intrathoracic Transplantation and Heart Failure Division, Favaloro Foundation - University Hospital, Buenos Aires, Argentina_

**(604)** Gender Differences in Clinical Characteristics and Outcomes in Patients Undergoing Heart Transplantation; __ C. Baum1, N. Ruebsamen1, F. M. Ojeda1, S. Blankenberg1, H. Reichenspurner2, R. B. Schnabel1, A. M. Bernhardt2. 1 _Department of General and Interventional Cardiology, Univ Heart Ctr Hamburg, Hamburg, Germany,_ 2 _Department of Cardiovascular Surgery, Univ Heart Ctr Hamburg, Hamburg, Germany_

**(605)** Strain Rejection Score to Diagnose Acute Cellular Rejection After Heart Transplantation; __ K. Antończyk1, M. Zakliczynski1, R. Antończyk1, M. Zembala1, T. Kukulski2. 1 _Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Silesian Center for Heart Diseases, Medical University of Silesia, Zabrze, Poland,_ 2 _Department of Cardiology, Congenital Heart Diseases and Electrotherapy, Silesian Center for Heart Diseases, Medical University of Silesia, Zabrze, Poland_

**(606)** Impact of Severe Renal Dysfunction on Outcomes of Isolated Heart Transplantation - A Single Centre Experience; __ B. Komarakshi1, M. Tanguturu2, K. G. Suresh Rao3, R. Ratnagiri4. 1 _Cardiac Surgery, Fortis Malar Hospital, Chennai, India,_ 2 _Cardiac Anesthesia & Critical Care, Fortis Malar Hospital, Chennai, India, _3 _Cardiac Anesthesia & Critical Care, Fortis Malar Hospital, Himeji, Japan, _4 _Cardiology, Fortis Malar Hospital, Chennai, India_

**(607)** Red Cell Distribution Width Predicts 1-Year Mortality Following Heart Transplantation; __ L. K. Truby, A. R. Garan, R. Givens, H. Takayama, K. Takeda, J. Haythe, M. Yuzefpolskaya, F. Latif, S. Restaino, E. Zorn, D. Mancini, Y. Naka, P. C. Colombo, M. Farr, V. K. Topkara. _Columbia University College of Physicians and Surgeons, New York, NY_

**(608)** ACE Inhibitors or ARBs - Do They Improve Outcome After Heart Transplantation?; __ M. Johl, J. Patel, M. Kittleson, L. Czer, T. Aintablian, A. Velleca, M. Hamilton, D. Geft, D. H. Chang, D. Ramzy, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(609)** Correlation of Individual Gene Expression Variability with the Variability of Combined Gene Expression Scores; __ E. C. DePasquale1, M. C. Deng1, S. Emani2, R. Woodward3, M. Machrus3, J. Sninsky3, S. Krim4. 1 _UCLA, Los Angeles, CA,_ 2 _Ohio State University Wexner Medical Center, Columbus, OH,_ 3 _CareDx, Brisbane, CA,_ 4 _Ochsner Medical Center, New Orleans, LA_

**(610)** Tricuspid Regurgitation in Heart Transplant Patients: The Relationship with Surgical Technique and Endomyocardial Biopsy; __ N. K. Bart, P. C. Jansz, P. S. Macdonald, M. Namasivayam, A. M. Keogh. _Heart Transplant, St Vincents Hospital, Sydney, Australia_

**(611)** Family Caregiver Activation in the Advanced Heart Failure Population Associated with 6-Month Mortality; __ S. A. Carey1, K. Bass1, K. M. Tecson2, J. Felius1, S. A. Hall1. 1 _Baylor University Medical Center, Dallas, TX,_ 2 _Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, TX_

**(612)** High Rate of Returning to Work After Heart Transplantation in Japan; __ K. Nawata1, O. Kinoshita1, M. Kimura1, H. Yamauchi1, M. Hatano2, Y. Hirata1, I. Komuro2, M. Ono1. 1 _Cardiac Surgery, The University of Tokyo Hospital, Tokyo, Japan,_ 2 _Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan_

**(613)** Walk the Line-Therapy of Rejection and BK Virus Nephropathy After Heart Transplantation; __ H. Grahn1, M. Rybszynski1, F. Wagner2, S. Blankenberg1, H. Reichenspurner2, M. Barten2. 1 _General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany,_ 2 _Clinics of Heart and Vascular Surgery, University Heart Center Hamburg, Hamburg, Germany_

## Infectious Diseases

(Seaport Foyer)

**Poster Discussants:** Young-Jae Cho, MD (Korea), Martha L Mooney, MD (USA), Simon Urschel, MD (Canada)

**(614)** Improving Hepatitis B Vaccination in Heart Transplant Candidates; __ E. S. Sukerman1, M. Fine2, M. Ackerman2, A. Chen3, S. Wedlake2, V. Stosor1. 1 _Infectious Diseases, Northwestern University, Chicago, IL,_ 2 _Cardiology, Northwestern University, Chicago, IL,_ 3 _Medicine, David Geffen School of Medicine UCLA, Los Angeles, CA_

**(615)** Is There a Role for Pre-Transplant Cytomegalovirus (CMV) Immunoglobulin G Optical Density to Predict CMV Infection in Seropositive Lung Transplant Recipients?; __ A. Hirji1, D. Kabbani2, C. Hernandez2, H. Malhi1, S. Chandrarathne1, K. Halloran1, A. Kapasi1, J. Weinkauf1, D. Lien1, J. Preiksaitis2, C. Cervera2. 1 _University of Alberta Lung Transplant Program, University of Alberta, Edmonton, AB, Canada,_ 2 _Division of Infectious Diseases, Department of Medicine, University of Alberta, Edmonton, AB, Canada_

**(616)** Management of Tuberculosis After Lung Transplantation in na Endemic Region; __ S. V. Campos1, M. N. Samano2, P. M. Pego-Fernandes2, R. O. Teixeira1, L. M. Fernandes2, L. G. Abdalla2, R. M. Carraro1, J. E. Afonso-Junior1, A. N. Costa1. 1 _Pneumology, Heart Institute of Sao Paulo Medical School, Sao Paulo, Brazil,_ 2 _Thoracic Surgery, Heart Institute of Sao Paulo Medical School, Sao Paulo, Brazil_

**(617)** WITHDRAWN

**(618)** Incidence and Characteristics of Cytomegalovirus Infection Among R+ Lung Transplant Recipients Receiving 3 Months of Antiviral Prophylaxis; __ D. Kabbani, A. Hijri, C. Hernandez Garcia, H. Malhi, S. Chandrarathne, A. Kapasi, J. Weinkauf, K. Halloran, D. Lien, J. Preiksaitis, C. Cervera. _University of Alberta, Edmonton, AB, Canada_

**(619)** Clinical Features Associated with Streptococcus pneumoniae in a Lung Transplant Recipients Cohort; __ C. Picard1, L. Beaumont1, E. Farfour2, A. Hamid1, G. Trebbia3, F. Parquin4, E. Sage4, A. Roux1. 1 _Respiratory Medicine, Foch Hospital, Suresnes, France,_ 2 _Microbiology Department, Foch Hospital, Suresnes, France,_ 3 _Intensive Care Unit, Foch Hospital, Suresnes, France,_ 4 _Thoracic Surgery, Foch Hospital, Suresnes, France_

**(620)** Correlation of Radiological Imaging with Microbiological Cure or Mortality from Invasive Pulmonary Aspergillosis (IPA) in Lung Transplant Recipients (LTRs); __ F. Alofi1, L. G. Singer2, D. Kumar1, A. Humar1, C. Rotstein1, S. Keshavjee2, S. Husain1. 1 _Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada,_ 2 _Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada_

**(621)** Role of Echinocandins as Antifungal Prophylaxis Agents in Lung Transplant Recipients; __ R. Pavan, S. Husain. _Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada_

**(622)** Voriconazole Therapeutic Drug Monitoring Among Lung Transplant Recipients Receiving Targeted Therapy for Invasive Aspergillosis; __ G. Butler-Laporte1, C. Poirier2, P. Ferraro3, M. Langevin3, C. Lemieux3, Y. Theoret4, M. Luong5. 1 _McGill University, Montreal, QC, Canada,_ 2 _Medicine, Division Respirology, Hopital Notre Dame, Montreal, QC, Canada,_ 3 _Hopital Notre Dame, Montreal, QC, Canada,_ 4 _Hopital Ste-Justine, Montreal, QC, Canada,_ 5 _St. Luc Hospital, Montreal, QC, Canada_

**(623)** EBV Related BOS Development Is Not Associated with Over-Immunosupression; __ J. Magnusson1, J. Westin2, R. Nordén2, L. Andersson3, G. Riise1. 1 _Pulmonary Medcine and Allergology, Institute of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden,_ 2 _Infectious Medicine, Institute of Biomedicine, Sahlgrenska University Hospital, Gothenburg, Sweden,_ 3 _Infectious Medicine, Institute of Biomedicine, Sahlgrenska University Hospital, Gothenburg, Sweden_

**(624)** Characteristics of Perioperative Airway Pathogens in Living and Cadaveric Lung Transplantation; __ H. Oda, T. F. Chen-Yoshikawa, Y. Goda, H. Kayawake, S. Ueda, M. Hamaji, H. Motoyama, K. Hijiya, A. Aoyama, H. Date. _Thoracic Surgery, Kyoto University Hospital, Kyoto City, Japan_

**(625)** Candida Blood Stream Infections Post Lung Transplant; __ S. K. Gadre1, C. Koval2, M. Budev1. 1 _Respiratory Institute, Cleveland Clinic Foundation, Cleveland, OH,_ 2 _Infectious Disease Institute, Cleveland Clinic Foundation, Cleveland, OH_

**(626)** Histoplasmosis in Adult Lung Transplant Recipients; __ Y. Furuya, C. Witt, E. P. Trulock, D. Byers, R. Yusen, R. Hachem. _Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, MO_

**(627)** Life on the Driveline; __ F. Schönrath1, J. Kikhney2, L. Kursawe1, K. Schönrath1, J. Schulze1, E. Potapov1, T. Krabatsch1, F. Kaufmann1, V. Falk1, A. Moter1. 1 _Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany,_ 2 _Institute for Microbiology and Hygiene, Charité University Hospital, Berlin, Germany_

**(628)** Antibiotic Prophylaxis Strategies in LVAD Implantation and LVAD Infections: A Systematic Review of the Literature; __ M. Bishawi, S. Bell, L. Cai, W. Landford, S. Arif, A. McLarty, L. Blue, B. Phillips, A. Nicoara, C. Patel, C. Milano. _Duke University, Durham, NC_

**(629)** Is Multidrugresistance Pathogens Colonization a Contraindication to LVAD Implant? A Single Center Experience; __ S. Sciacca1, G. Panarello2, M. O. Campanella3, R. Alduino3, F. Clemenza4, M. Pilato1. 1 _Cardiac Surgery, ISMETT, Palermo, Italy,_ 2 _Anesthesia, ISMETT, Palermo, Italy,_ 3 _ISMETT, Palermo, Italy,_ 4 _Cardiology, ISMETT, Palermo, Italy_

**(630)** Long Term Management of Deep Mediastinal Infection for Durable Mechanical Circulatory Support Devices; __ D. G. Tang1, O. De La Cruz2, M. Quader3, V. Kasirajan3. 1 _Virginia Commonwealth University, Richmond, VA,_ 2 _Division of Infectious Diseases, Virginia Commonwealth University, Richmond, VA,_ 3 _Cardiothoracic Surgery, Virginia Commonwealth University, Richmond, VA_

**(631)** Contemporary Report on Infectious Complications in Pediatric Patients Supported by Ventricular Assist Devices; __ A. G. Cabrera1, J. F. Price1, I. Adachi2, A. Jeewa1, B. Elias2, S. W. Denfield1, W. J. Dreyer1, G. F. Jason1, N. J. Rodgers1, J. Vallejo1, C. E. Bocchini1. 1 _Pediatrics, Baylor College of Medicine/Texas Children's Hospital, Houston, TX,_ 2 _Surgery, Baylor College of Medicine/Texas Children's Hospital, Houston, TX_

## Mechanical Circulatory Support

(Regatta Foyer)

**Poster Discussants:** Deepak Acharya, MD (USA), Mary M Bradbury, PharmD (USA), Fabio De Robertis, MD (United Kingdom), Shashank S Desai, MD (USA), Sangjin Lee, MD (USA), Anna L Meyer, MD (Germany), Sebastian G A Michel, MD (Germany), Ezequiel J Molina, MD (USA), Jia Lin Soon, FRCS (CTh) (Singapore), Diyar Saeed, MD (Germany), Josef Stehlik, MD, MPH (USA), Nir Uriel, MD (USA)

**(632)** Bivalirudin Experience in a Heterogenous VAD Population; __ J. L. Conway1, A. Bates2, D. Freed3, R. MacArthur4, H. Buchholz4. 1 _Division of Cardiology, Department of Paediatrics, University of Alberta, Stollery Children's Hospital, Edmtonton, AB, Canada,_ 2 _Division of Critical Care Medicine, Department of Paediatrics, University of Alberta, Stollery Children's Hospital, Edmtonton, AB, Canada,_ 3 _Surgery, Division of Cardiac Surgery, University of Alberta, Edmtonton, AB, Canada,_ 4 _Division of Cardiac Surgery, University of Alberta, Edmtonton, AB, Canada_

**(633)** Experience and Perspective of Heparin -Antiplatelet Factor IV Antibody Testing for the Diagnosis of Heparin Induced Thrombocytopenia in Veno-Arterial Extracorporeal Membrane Oxygenation; __ H. M. Gonzalez Bonilla1, P. A. Alvarez2, D. Hailemariam3, R. Ogunti3, M. Puppala3, S. N. Homer3, F. R. Bostan3, J. E. Fetter4, L. Rice5. 1 _Internal Medicine, Houston Methodist Hospital, Houston, TX,_ 2 _Houston Methodist DeBakey Heart and Vascular Center, Houston Methodist Hospital, Houston, TX,_ 3 _Houston Methodist Hospital, Houston, TX,_ 4 _Anesthesia and Critical Care, Houston Methodist Hospital, Houston, TX,_ 5 _Hematology Department, Houston Methodist Hospital, Houston, TX_

**(634)** Pump Thrombosis in Japanese Patients with HeartMate II Continuous-Flow LVAD Pump Thrombosis in Japanese Patients with HeartMate II Continuous-Flow LVAD; __ M. Ono1, Y. Sawa2, N. Fukushima3, Y. Saiki4, A. Shiose5, G. Matsumiya6, H. Arai7. 1 _Dept. of Cardiac Surgery, University of Tokyo, Tokyo, Japan,_ 2 _Dept. of Cardiovascular Surgery, Osaka University, Osaka, Japan,_ 3 _National Cerebral and Cardiovascular Research Center, Osaka, Japan,_ 4 _Dept. of Cardiovascular Surgery, Tohoku University, Sendai, Japan,_ 5 _Dept. of Cardiovascular Surgery, Kyushu University, Fukuoka, Japan,_ 6 _Dept. of Cardiovascular Surgery, Chiba University, Chiba, Japan,_ 7 _Dept. of Cardiovascular Surgery, Tokyo Medical Dental University, Tokyo, Japan_

**(635)** Management of RVAD Thrombosis in Biventricular HVAD Supported Patients; __ J. Silva Enciso, M. Brambatti, H. Tran, G. V. Pretorius, E. Adler. _Department of Cardiology, University of California San Diego, San Diego, CA_

**(636)** In Vitro Acoustic Fingerprint of an Axial Cone Bearing Left Ventricular Assist Device; __ G. Di Giammarco, D. Marinelli, R. Navarra. _Dipartimento di Neuroscienze,Imaging e Scienze Cliniche, University, Chieti, Italy_

**(637)** Hemostatic Analyzes of HeartMate II Patients Surviving without Anticoagulation; __ R. Zayat, M. A. Khattab, A. Goetzenich, H. Steffen, M. Shoaib, N. Chernigov, L. Tewarie, A. Moza, R. Autschbach. _Department of Thoracic and Cardiovascular Surgery, RWTH University Hospital, Aachen, Germany_

**(638)** Early Post-Implant Lactate Dehydrogenase Level and LVAD Thrombosis: A Comparison of Heartmate II and Heartmate III; __ S. Lim, T. Musa, N. Howell, A. Ranasinghe, J. Mascaro. _University Hospital Birmingham, Birmingham, United Kingdom_

**(639)** Role of Pre-Operative Right Ventricle Longitudinal Strain in Predicting Gastrointenstinal Bleeding in Patients with Continuos Flow Left Ventricular Assist Devices; __ M. Brambatti1, J. Silva Enciso1, H. Tran1, A. Mizeracki1, C. J. Baeza1, G. V. Pretorius2, E. Adler1. 1 _Department of Cardiology, University of California San Diego, La Jolla, CA,_ 2 _Department of Cardiothoracic Surgery, University of California San Diego, La Jolla, CA_

**(640)** Is Bridging Anticoagulation Required in LVAD Patients with Subtherapeutic INR?; __ D. C. Shisler1, R. Vijayakrishnan1, A. J. Lenneman1, E. J. Birks1, L. Muncy1, M. Slaughter2, D. Abramov1. 1 _Cardiovascular Medicine, University of Louisville, Louisville, KY,_ 2 _Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, KY_

**(641)** Evaluation of Thalidomide in Left Ventricular Assist Device Associated Gastrointestinal Bleeding; __ K. Blunck1, A. Wendel2, M. Everley3, S. Aggarwal4. 1 _Pharmacy, Saint Luke's Hospital, Kansas City, MO,_ 2 _VAD Program, Saint Luke's Hospital, Kansas City, MO,_ 3 _Saint Luke's Cardiovascular Consultants, Kansas City, MO,_ 4 _Mid America Heart and Lung Surgeons, Kansas City, MO_

**(642)** Low Dose tPA as a Therapeutic Strategy in Suspected Pump Thrombosis in HeartMate II; __ A. S. Cruz-Solbes, M. I. Achi, J. Amione-Guerra, E. Karanja, B. Trachtenberg, A. Bhimaraj, J. Estep, G. Torre-Amione, I. Hussain, M. Park, B. Bruckner, A. Guha. _Methodist DeBakey Heart Center, Houston Methodist Hospital, Houston, TX_

**(643)** Hemolysis and Von Willebrand Factor Levels During Continuous Flow Left Ventricular Assist Device Support; __ O. Saeed1, S. Rangasamy1, A. Luke1, S. R. Patel1, J. Shin1, D. B. Sims1, M. Reyes Gil2, D. J. Goldstein3, M. J. Slepian4, H. H. Billett2, U. Jorde1. 1 _Medicine (Cardiology), Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY,_ 2 _Medicine (Hematology), Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY,_ 3 _Surgery (Cardiothoracic), Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY,_ 4 _Medicine (Cardiology), University of Arizona, Bronx, AZ_

**(644)** The Effect of Recombinant-Activated Factor VII on Patients Requiring ECMO Support; __ H. Merritt Genore, S. Smith, I. Shoiab, A. Siddique, E. Lyden, T. Ryan, J. Um, A. Burdorf, M. Moulton. _Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE_

**(645)** WITHDRAWN

**(646)** Per-Interventional Discontinuation of Anticoagulation Appears Safe in Patients with HeartMate 3; __ H. Kirov, G. Faerber, T. Sandhaus, S. Tkebuchava, T. Doenst. _Department of Cardiothoracic Surgery, University Hospital Jena, Jena, Germany_

**(647)** The Effect of HeartMate2 and HeartMate3 Implantation on Plasma Markers of Angiogenesis and Inflammation; __ C. E. Tabit1, G. H. Kim1, J. Maly2, G. Sayer1, Z. Tucanova2, S. Adatya1, P. Ivak2, N. Uriel1, I. Netuka2. 1 _Cardiology, The University of Chicago Medical Center, Chicago, IL,_ 2 _Institute for Clinical and Experimental Medicine, Prague, Czech Republic_

**(648)** Thromboelastogram Directed Anticoagulation After Left Ventricular Assist Device Implantation; __ M. Abdou1, R. J. Chen2, I. Wang2, E. Gleissner3, J. Pickrell3, M. Caccamo1, A. Hadi1. 1 _Division of Cardiology, Indiana University, Indianapolis, IN,_ 2 _Division of Cardiothoracic Surgery, Indiana University, Indianapolis, IN,_ 3 _Cardiology Service Line, Indiana University, Indianapolis, IN_

**(649)** Use of Pre-Device Exchange Computed Tomography Angiography for Left Ventricular Assist Device Thrombosis; __ S. N. Yu1, J. Han1, K. Takeda2, J. N. Ginns3, P. A. Kurlansky2, A. R. Garan3, M. Yuzefpolskaya3, V. K. Topkara1, P. C. Colombo3, Y. Naka2, H. Takayama2. 1 _Columbia University Medical Center, New York, NY,_ 2 _Division of Cardiothoracic Surgery, Columbia University Medical Center, New York, NY,_ 3 _Division of Cardiology, Columbia University Medical Center, New York, NY_

**(651)** Markers of Coagulation and Hemostasis Activation in Left Ventricular Assist Device Recipients; __ A. F. Moorman, M. L. Hurtik, A. Pekarek, S. Laskar, D. Gupta. _Emory University Hospital, Atlanta, GA_

**(652)** Preoperative Predictors of Surgical Bleeding with Implantation of Durable Mechanical Circulatory Support Devices; __ K. Lietz1, C. Barreiro1, J. Philpott1, C. Flink2, M. McGrath1, J. Herre1. 1 _Division of Advanced Heart Failure, Sentara Heart Hospital, Norfolk, VA,_ 2 _Sentara Cardiovascular Research Institute, Norfolk, VA_

**(653)** De-Airing Method of HeartMate II LVAD Influences Post-Operative LDH: A Possible Explanation for Some Thrombotic Events; __ D. Tanaka1, A. Boyle2, J. W. Entwistle1. 1 _Cardiothoracic Surgery, Thomas Jefferson University, Philadelphia, PA,_ 2 _Cardiology, Thomas Jefferson University, Philadelphia, PA_

**(654)** Bridging Anti-Coagulation with Low-Molecular-Weight Heparin in HVAD Patients - A Safe and Effective Option; __ B. Schrage, J. Braetz, A. Bernhardt, M. Rybczynski, M. Barten, H. Reichenspurner, S. Blankenberg, H. Grahn. _University Heart Center Hamburg, Hamburg, Germany_

**(655)** Management of Antiplatelet Therapy During Left Ventricular Assist Device Support After Thrombo-Hemorrhagic Events; __ M. Gallo, J. R. Trivedi, E. J. Birks, D. Abramov, M. S. Slaughter. _Department of Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, KY_

**(656)** Prior Clotting Events as Predictors of Post LVAD Morbidity and Mortality; __ J. Johannesen1, J. Whittier2, S. Feitell1, S. R. Hankins2, W. Fischer3, H. J. Eisen2. 1 _Medicine, Drexel University, Philadelphia, PA,_ 2 _Cardiology/Medicine, Drexel University, Philadelphia, PA,_ 3 _Cardiothoracic Surgery, Drexel University, Philadelphia, PA_

**(657)** Antiphospholipid Syndrome in Patients with Left Ventricular Assist Device; __ A. Al-Naamani1, A. L. Meyer1, K. Jawad1, J. Fischer1, A. Siegemund2, T. Siegemund2, A. Oberbach1, J. Hahn1, S. Lehmann1, F. W. Mohr1, J. Garbade1. 1 _Leizpig Heart Center, Leizpig, Germany,_ 2 _MVZ Labor Leipzig, Leizpig, Germany_

**(658)** Incidence of Gastrointestinal Bleeding and Acquired von Willebrand Syndrome in Japanese Recipients of Continuous-Flow Left Ventricular Assist Devices -Comparison Between Axial and Centrifugal-Flow Pumps; __ S. Nakajima1, K. Kuroda1, H. Sunami1, T. Sato1, O. Seguchi1, M. Yanase1, Y. Matsumoto2, H. Hata2, T. Fujita2, J. Kobayashi2, N. Fukushima1. 1 _Department of Transplant Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan,_ 2 _Department of Adult Cardiac Surgery, National Cerebral and Cardiovascular Center, Osaka, Japan_

**(659)** Examining Pump Exchange and Laboratory Markers of Organ Function Among LVAD Related Hospitalizations for Hemolytic Events; __ G. Murtaza, T. Yousuf, C. Kabir, C. Desai. _UIC/Advocate Christ Medical Center, Oak Lawn, IL_

**(660)** The Impact of LVAD Pump Thrombosis (PT) on Renal Function in Patients Undergoing Continuous Flow (CF) Left Ventricular Device (LVAD) Exchange; __ F. Kamdar1, M. Urban2, D. Szczech3, R. John3, R. C. Starling2, N. Moazami2. 1 _Cleveland Clinic, University of Minnesota, Minneapolis, MN,_ 2 _Cleveland Clinic, Cleveland, OH,_ 3 _University of Minnesota, Minneapolis, MN_

**(661)** Pre-Implant Atrial Fibrillation Predicts Gastrointestinal Bleeding Following Left Ventricular Assist Device Implantation; __ M. A. Psotka1, J. Svetlichnaya1, V. N. Selby1, M. Janmohamed1, T. De Marco1, G. Wieselthaler2, L. Klein1. 1 _Cardiology, University of California San Francisco, San Francisco, CA,_ 2 _Cardiothoracic Surgery, University of California San Francisco, San Francisco, CA_

**(662)** Does Angiotensin Pathway Inhibition Influence Non-Surgical Bleeding in Durable Mechanical Circulatory Support?; __ J. W. Schurr1, C. A. Stevens2, L. Coakley1, M. Mehra1. 1 _Brigham and Women's Hospital, Boston, MA,_ 2 _UC San Diego Medical Center, San Diego, CA_

**(663)** Outcomes of Low Dose Strategy of Thrombolytic Therapy for Pump Thrombosis; __ S. Ertugay1, P. Ozturk1, C. Engin1, E. Demir2, S. Nalbantgil2, T. Yagdi1, M. Ozbaran1. 1 _Cardiovascular Surgery, Ege University Medical School Hospital, IZMIR, Turkey,_ 2 _Cardiology, Ege University Medical School Hospital, IZMIR, Turkey_

**(664)** Outcomes of Asian-Americans Undergoing Left Ventricular Assist Device Implantations as a Bridge to Transplant or Destination Therapy: An INTERMACS Analysis; __ J. R. Wever Pinzon1, W. Wang2, N. Hu3, R. Larsen1, T. Yu2, L. Yin2, I. Taleb1, A. Koliopoulou1, S. Mckellar1, J. Stehlik1, J. Fang1, A. Kfoury4, C. Selzman1, S. Drakos1. 1 _Cardiovascular Medicine, University of Utah, Salt Lake City, UT,_ 2 _Cardiovascular Medicine, Sichuan Academy of Sciences, Chengdu, China,_ 3 _University of Utah, Salt Lake City, UT,_ 4 _Cardiovascular Medicine, Intermountain Medical Center, Salt Lake City, UT_

**(665)** Increased Frequency of Bleeding Complications in Females Following LVAD Implant; __ Z. Yavar, J. Cowger, S. Moainie, C. Salerno, A. K. Ravichandran. _St. Vincent Heart Center of Indiana, Indianapolis, IN_

**(666)** Post-Operative Bridging Anticoagulation and HeartMate II Pump Thrombosis; __ D. M. Nemer1, J. M. Connors2, M. Puligandla3, D. S. Neuberg3, G. C. Stewart4. 1 _Division of Hospital Medicine, Brigham and Women's Hospital, Boston, MA,_ 2 _Division of Hematology, Brigham and Women's Hospital, Boston, MA,_ 3 _Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA,_ 4 _Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA_

**(667)** Medical Management of Device Thrombosis in Continuous-Flow Left Ventricular Assist Device Patients: Success Rate and Outcomes; __ E. Coromilas1, R. Garan1, M. Yuzefpolskaya1, H. Takayama2, K. Takeda2, M. Farr1, Y. Naka2, P. C. Colombo1, V. K. Topkara1. 1 _Medicine, Columbia University, New York, NY,_ 2 _Surgery, Columbia University, New York, NY_

**(668)** Low Antithrombin Levels Pre-ECMO May Predict Venous Thromboembolism After Lung Transplantation; __ E. Todd1, S. Biswas Roy1, P. Kang2, H. Abdelrazek1, R. Walia1, R. M. Bremner1, M. A. Smith1. 1 _Norton Thoracic Institute, St. Joseph's Hospital & Medical Center, Phoenix, AZ, _2 _University of Arizona College of Public Health, Phoenix, AZ_

**(669)** Anti-Platelet Drug Efficacy In Vitro Under VAD-Like Shear Stress Conditions; __ L. Valerio1, P. L Tran2, M. Hutchinson2, F. Consolo1, A. Redaelli1, M. Slepian2. 1 _Politecnico di Milano, Milano, Italy,_ 2 _University of Arizona, Tucson, AZ_

**(670)** Prospective Evaluation of Urine Dipstick for Detection of Moderate and Severe Hemolysis in Outpatients on CF-LVAD Support; __ M. V. Gavalas, A. Breskin, P. N. Trinh, H. Rosenblum, M. Yuzefpolskaya, A. Eisenberger, A. R. Garan, A. Pinsino, B. Cagliostro, M. Flannery, H. Takayama, K. Takeda, Y. Naka, V. K. Topkara, P. C. Colombo. _New York Presbyterian Hospital - Columbia University Medical Center, New York, NY_

**(671)** Very Low Incidence of Clinically Significant Thrombocytopenia After Extended Intra Aortic Balloon Pump Support; __ J. Amione-Guerra, A. Ali, A. S. Cruz-Solbes, R. Araujo-Gutierrez, B. H. Trachtenberg, A. Bhimaraj, A. Guha, M. Park, J. D. Estep, G. Torre-Amione. _Methodist DeBakey Heart Center, Houston Methodist Hospital, Houston, TX_

**(672)** Early Detection of Pump Thrombosis in Patients with Left Ventricular Assist Device; __ J. Grabska1, T. Schlöglhofer2, C. Gross1, K. Dimitrov3, D. Wiedemann3, D. Zimpfer3, H. Schima2, F. Moscato1. 1 _Center for Medical Physics and Biomedical Engineering, Medical University of Vienna; Ludwig-Boltzmann-Cluster for Cardiovascular Research, Vienna, Austria,_ 2 _Center for Medical Physics and Biomedical Engineering, Department of Cardiac Surgery, Medical University of Vienna; Ludwig-Boltzmann-Cluster for Cardiovascular Research, Vienna, Austria,_ 3 _Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria_

**(674)** Safety and Efficacy of Thalidomide in the Treatment of Recurrent Gastrointestinal Bleeding in Patients on Left Ventricular Assist Device Support; __ C. Lim1, M. Lim1, L. Teo1, L. Chan1, K. Kerk2, D. Sim1, T. Tan2, C. Sivathasan2. 1 _Cardiology, National Heart Centre Singapore, Singapore, Singapore,_ 2 _Cardiothoracic Surgery, National Heart Centre Singapore, Singapore, Singapore_

**(675)** Negative Pressure Dressings Reduce the Incidence of Driveline Infections Following LVAD Implantation; __ K. Balsara, L. Jolliff, M. Masood, A. Itoh. _Surgery, Washington University in St Louis, St Louis, MO_

**(676)** Mycobacterium Abscessus Infection in Patients with Ventricular Assist Devices; __ C. R. Wolfe1, A. W. Baker1, C. B. Patel1, P. A. Patel1, C. A. Milano1, J. N. Schroder1, M. A. Daneshmand1, B. D. Alexander1, E. K. Maziarz2. 1 _Duke University Medical Center, Durham, NC,_ 2 _Infectious Disease, Duke University Medical Center, Durham, NC_

**(677)** Anonymous Driveline Care Survey Reveals Home Driveline Care Practices; __ D. Szczech1, M. Thompson1, L. Hamann1, R. John2, R. Cogswell3. 1 _CV Specialty Nursing, University of MN Health, Minneapolis, MN,_ 2 _CV Surgery, University of MN Health, Minneapolis, MN,_ 3 _Cardiology, University of MN Health, Minneapolis, MN_

**(678)** C-Reactive Protein (CRP) Correlates Poorly with Infection in the Post-Surgical Period Following Left Ventricular Assist Device (LVAD) Implantation; __ E. J. McKay1, K. Heyes1, P. Chaggar1, P. Foden2, S. Williams1, J. Bernard1, N. Yonan1, R. Venkateswaran1, S. M. Shaw1, E. Muldoon1. 1 _The Transplant Unit, University Hospital South Manchester, Manchester, United Kingdom,_ 2 _Medical Statistics, University Hospital South Manchester, Manchester, United Kingdom_

**(679)** Greater Omentum Plasty for the Treatment of Deep Driveline Infection in Chronic Mechanical Circulatory Support; __ S. Schulte Eistrup1, J. D. Schmitto2, N. Reiss3, O. Gaubitz1, A. Schmidtke4, R. Bach1, H. Warnecke1. 1 _Cardiac Surgery, Schuechtermann Klinik, Bad Rothenfelde, Germany,_ 2 _Cardiac Surgery, Medical School, Hannover, Germany,_ 3 _Rehabilitation, Schuechtermann Klinik, Bad Rothenfelde, Germany,_ 4 _Gerneral Surgery, Marienhospital, Osnabrück, Germany_

**(680)** Association of Body Mass Index and Age on Risk of Driveline Infection Post Ventricular Assist Device Implantation; __ T. Schofield, F. Foroutan, S. Ryoo, K. O'Brien, A. C. Alba, S. Hussain, V. Rao, H. Ross, F. Billia. _Cardiology, Toronto General Hospital, Toronto, ON, Canada_

**(681)** Bridge to Transplant Status Is Associated with Improved Survival After the Development of Left Ventricular Assist Device Infection ; __ A. Leuck1, J. Schultz2, F. Mazzulla2, R. John3, J. Spratt3, A. N. Walts4, R. Cogswell4. 1 _Infectious Disease, University of Minnesota, Minneapolis, MN,_ 2 _Medicine, University of Minnesota, Minneapolis, MN,_ 3 _Cardiothoracic Surgery, University of Minnesota, Minneapolis, MN,_ 4 _Cardiology, University of Minnesota, Minneapolis, MN_

**(682)** Bloodstream Infections in Continuous Flow Left Ventricular Assist Device Recipients: The Utility of Systemic Inflammatory Response Syndrome for Diagnosing Sepsis and Prediction of Mortality; __ A. Kyvernitakis1, O. Pappas2, A. Wani1, D. Farmakiotis3, E. T. Horn4, S. Murali2, R. L. Benza2, S. H. Bailey5, R. Agarwal2. 1 _Internal Medicine, Allegheny General Hospital, Pittsburgh, PA,_ 2 _Cardiovascular Disease, Allegheny General Hospital, Pittsburgh, PA,_ 3 _Infectious Diseases, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, RI,_ 4 _Pharmacy, Allegheny General Hospital, Pittsburgh, PA,_ 5 _Cardiothoracic Surgery, Allegheny General Hospital, Pittsburgh, PA_

**(683)** Echocardiographic and Hemodynamic Characteristics of Total Artificial Heart Recipients; __ E. J. Sawey, J. T. Owens, R. Cooke, V. Kasirajan, R. Markley, K. Rao, M. C. Smallfield, D. Tang, I. Tchoukina, K. B. Shah. _Cardiology, VCU, Richmond, VA_

**(684)** High Intensity Activity with a Subclavian Artery Intra-Aortic Balloon Pump; __ M. Stulberg1, C. Stratton1, V. Jeevanandam2. 1 _Therapy Services, University of Chicago Medicine, Chicago, IL,_ 2 _Cardiac & Thoracic Surgery, University of Chicago Medicine, Chicago, IL_

**(686)** Telemonitoring in LVAD-Patients: Acceptance and Need; __ C. Feldmann1, E. Deniz1, T. Schmidt2, J. Hoffmann2, J. S. Hanke1, S. V. Rojas1, G. Dogan1, D. Berliner1, C. Bara1, C. Bara1, G. Warnecke1, A. Haverich1, J. D. Schmitto1, N. Reiss2. 1 _Hannover Medical School, Hannover, Germany,_ 2 _Schüchtermann Klinik, Bad Rothenfelde, Germany_

**(687)** Prolonged Circulatory Support (Five Years or Longer) with Left Ventricular Assist Devices for Patients with Advanced Heart Failure; __ A. Segura1, A. Nair2, C. Kurihara2, S. Carranza1, A. Civitello2, J. Morgan2, O. Frazier1. 1 _Texas Heart Institute, Houston, TX,_ 2 _Baylor College of Medicine, Houston, TX_

## Pediatrics

(Harbor Foyer)

**Poster Discussants:** Christopher Almond, MD (USA), Estela Azeka, MD (Brazil), Ching Kit Chen, MBBS, MRCPCH (Singapore), Kevin P Daly, MD (USA), Anne I Dipchand, MD (Canada), Kristine J Guleserian, MD (USA), Jonathan N Johnson, MD (USA), Janet N Scheel, MD (USA)

**(688)** Self-Reported and Directly Measured Physical Activity in Children and Youth with Cardiomyopathies; __ J. Conway1, L. Glass1, C. Cunningham1, J. Stearns2, V. Carson2, P. F. Kantor1, S. Urschel1, J. C. Spence2. 1 _Stollery Children's Hospital, Edmonton, AB, Canada,_ 2 _University of Alberta, Edmonton, AB, Canada_

**(689)** WITHDRAWN

**(690)** Ventricular Arterial Coupling: A Novel Echocardiographic Risk Factor for Poor Outcome in PAtients with Acute Decompensated Heart Failure; __ C. A. Capone, J. Lorenzo, B. Tria, S. S. Medar, S. I. Aydin, J. M. Lamour, D. T. Hsu, J. Mahgerefteh. _The Children's Hospital of Montefiore-Albert Einstein College of Medicine, Bronx, NY_

**(691)** Hospitalization-Related Resource Utilization in Congenital Heart Disease with Advanced Heart Failure; __ D. S. Burstein1, P. Shamszad1, C. S. Almond2, J. F. Price3, K. Y. Lin1, M. J. O'Connor1, R. E. Shaddy1, C. E. Mascio1, J. W. Rossano1. 1 _Pediatric Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA,_ 2 _Pediatric Cardiology, Stanford Childrens Hospital, Palo Alto, CA,_ 3 _Pediatric Cardiology, Texas Children's Hospital, Houston, TX_

**(692)** Peak Troponin I Is Associated with Death and Extracorporeal Membrane Oxygenation in Pediatric Myocarditis; __ A. Butto1, J. Rossano1, D. Nandi2, C. Ravishankar1, K. Y. Lin1, M. J. O'Connor1, R. E. Shaddy1, P. Shamszad1. 1 _Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA,_ 2 _Cardiology, The Heart Center, Nationwide Children's Hospital, Columbus, OH_

**(693)** The Association of Carvedilol Use on Transplant Free Survival in Pediatric Patients with Dilated Cardiomyopathy: An Analysis from the Pediatric Cardiomyopathy Registry; __ J. W. Rossano1, L. J. Addonizio2, C. E. Canter3, S. D. Colan4, D. A. Dodd5, M. D. Everitt6, B. Harty7, D. Hsu8, J. L. Jefferies9, P. F. Kantor10, A. Lal11, J. M. Lamour8, T. M. Lee2, E. Pahl12, L. Shi7, J. A. Towbin13, S. M. Ware14, S. A. Webber5, J. D. Wilkinson15, S. E. Lipshultz15. 1 _Cardiology, The Children 's Hospital of Philadelphia, Philadelphia, PA,_ 2 _Morgan Stanley Children's Hospital, New York, NY,_ 3 _Washington University School of Medicine, St. Louis, MO,_ 4 _Boston Children's Hospital, Boston, MA,_ 5 _Vanderbilt University, Nashville, TN,_ 6 _Children's Hospital Colorado, Denver, CO,_ 7 _New England Research Institutes, Watertown, MA,_ 8 _Children's Hospital at Montefiore, Bronx, NY,_ 9 _Cincinnati Children's Hospital Medical Center, Cincinnati, OH,_ 10 _Stollery Children's Hospital, Edmonton, AB, Canada,_ 11 _Primary Children's Hospital, Salt Lake City, UT,_ 12 _Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, _13 _Le Bonheur Children's Hospital, Memphis, TN,_ 14 _Indiana University School of Medicine, Indianapolis, IN,_ 15 _Wayne State University School of Medicine, Detroit, MI_

**(694)** Utilizing HCV and HBV Infected Donor Organs for Pediatric Thoracic Transplantation; __ Y. Radzi1, L. Danziger-Isakov2, R. Bryant III1, C. Chin3, D. Morales1, F. Zafar1. 1 _Division of Cardiothoracic Surgery, Cincinnati Children's Hospital, Cincinnati, OH,_ 2 _Division of Infectious Diseases, Cincinnati Children's Hospital, Cincinnati, OH,_ 3 _Division of Cardiology, Cincinnati Children's Hospital, Cincinnati, OH_

**(695)** Mixed Rejection in Pediatric Heart Transplant Patients : An Observational Study; __ L. X. Wu1, M. Carroll2, W. T. Mahle3, S. R. Deshpande3. 1 _Pediatrics, Emory University, Atlanta, GA,_ 2 _Children's Healthcare of Atlanta, Atlanta, GA,_ 3 _Pediatric Cardiology, Emory University Children's Healthcare of Atlanta, Atlanta, GA_

**(696)** Old Dogs with New Tricks: A Standardized Flow Cytometry Panel Measuring Donor-Recipient Alloreactivity; __ A. Halpin1, M. Sosniuk2, S. Urschel3, P. Campbell4, I. Larsen5, L. West3. 1 _Dept of Pediatrics, Laboratory Medicine and Pathology, Canadian National Transplant Research Program, University of Alberta, Edmonton, AB, Canada,_ 2 _Department of Pediatrics, University of Alberta, Edmonton, AB, Canada,_ 3 _Dept of Pediatrics, Alberta Transplant Institute, Canadian National Transplant Research Program, University of Alberta, Edmonton, AB, Canada,_ 4 _Dept of Laboratory Medicine and Pathology, Alberta Transplant Institute, University of Alberta, Edmonton, AB, Canada,_ 5 _Dept of Pediatrics, Alberta Transplant Institute, University of Alberta, Edmonton, AB, Canada_

**(697)** The Impact of Pediatric Ventricular Assist Device Support Before Cardiac Transplant on Post-Transplant Outcomes; __ H. P. Tunuguntla1, S. W. Denfield1, K. Puri1, I. Adachi2, A. G. Cabrera1, N. J. Rodgers1, J. Goldberg1, J. F. Price1, W. J. Dreyer1, A. Jeewa1. 1 _Pediatric Cardiology, Baylor College of Medicine, Houston, TX,_ 2 _Congenital Heart Surgery, Baylor College of Medicine, Houston, TX_

**(698)** Maximizing Survival in Hypoplastic Left Heart Syndrome: Evolution of a Balanced Institutional Strategy; __ T. Karamlou1, S. Zangwill2, S. Pophal2, D. Velez1, J. Nigro1. 1 _Pediatric Cardiac Surgery, Phoenix Children's Hospital, Phoenix, AZ,_ 2 _Pediatric Cardiology, Phoenix Children's Hospital, Phoenix, AZ_

**(699)** Center Variability in Selecting High-Risk Donors: Does It Affect the Outcomes in Pediatric Heart Transplantation?; __ R. Rizwan1, F. Zafar1, R. Bryant III1, C. Chin2, A. Lorts2, J. S. Tweddell1, D. L. Morales1. 1 _Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH,_ 2 _Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH_

**(700)** Pediatric Heart Transplantation: Transitioning to Adult Care; __ E. Pahl1, K. Van't Hof1, A. Andrei2, T. Shankel3, R. Chinnock3, S. Miyamoto4, A. Ambardekar5, L. Addonizio6, F. Latif6, D. Lefkowitz7, L. Goldberg8, S. Hollander9, M. Pham9, K. Grady10. 1 _Cardiology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, _2 _Northwestern University, Chicago, IL,_ 3 _Loma Linda University Medical Center, Loma Linda, CA,_ 4 _Children's Hospital Colorado, Aurora, CO,_ 5 _University of Colorado Hospital, Aurora, CO,_ 6 _Columbia University Medical Center, New York, NY,_ 7 _The Children's Hospital of Philadelphia, Philadelphia, PA,_ 8 _University of Pennsylvania, Philadelphia, PA,_ 9 _Stanford University, Palo Alto, CA,_ 10 _Northwestern Memorial Hospital, Chicago, IL_

**(701)** Understanding Hypertension in Pediatric Patients After Heart Transplantation; __ P. Patel1, K. LaPorte2, M. Carroll2, W. T. Mahle1, K. Kanter3, S. R. Deshpande1. 1 _Pediatric Cardiology, Emory University Children's Healthcare of Atlanta, Atlanta, GA,_ 2 _Heart Transplantation, Children's Healthcare of Atlanta, Atlanta, GA,_ 3 _Department of Cardiothoracic Surgery, Emory University, Atlanta, GA_

**(702)** Incidence and Risk Factors for Failed Recovery of Pediatric Donor Hearts; __ A. Ghavam1, N. Ghanayem1, R. K. Woods2, S. J. Kindel3, N. E. Thompson1. 1 _Pediatric Critical Care, Medical College of Wisconsin, Milwaukee, WI,_ 2 _Cardiothoracic Surgery, Medical College of Wisconsin, Milwaukee, WI,_ 3 _Pediatric Cardiology, Medical College of Wisconsin, Milwaukee, WI_

**(703)** Relationship Between eGFR and Survival Before and After Heart Transplantation in Children; __ R. R. Davies, M. A. McCulloch, C. Brailer, C. Pizarro. _Nemours Cardiac Center, Nemours/A.I. duPont Hospital for Children, Wilmington, DE_

**(704)** Correlation of Allomap® Scores in Pediatric Heart Transplant Recipients: Are We Ready to Apply This to Our Patients?; __ D. Gupta, S. Bartra, R. Shih, L. M. Breault, M. S. Bleiweis, F. J. Fricker, B. A. Pietra. _Congenital Heart Center, Department of Pediatrics, University of Florida, Gainesville, FL_

**(705)** Do the Characteristics and Outcomes of Pediatric Patients with Restrictive Cardiomyopathy Differ from Those with Dilated Cardiomyopathy?A UNOS Database Analysis; __ K. Ramakrishnan1, J. Collins2. 1 _Children's National Health System, Washington, DC,_ 2 _MUSC, Charleston, SC_

**(706)** Avoidance of a C1q Positive Crossmatch Prevents Both Early and Late Antibody-Mediated Rejection in Pediatric Heart Transplant Recipients; __ S. A. Hollander1, D. M. Peng2, M. Mills3, G. J. Berry4, M. Pedrigo5, S. Chen1, D. B. Tyan4, D. Bernstein1, D. N. Rosenthal1. 1 _Pediatrics (Cardiology), Stanford University, Palo Alto, CA,_ 2 _Pediatrics (Cardiology), University of Michigan, Ann Arbor, MI,_ 3 _Pediatrics, Stanford University, Palo Alto, CA,_ 4 _Pathology, Stanford University, Palo Alto, CA,_ 5 _Pathology, University of Padova, Padova, Italy_

**(707)** A Minimal Biopsy Reliant Surveillance for Rejection in Children Is Not Associated with Inferior Outcomes Post-Heart Transplant; __ P. D. Evers1, N. Jorgensen2, B. Hong3, E. Albers3, M. Kemna3, J. Friedland-Little3, Y. Law3. 1 _Pediatric Cardiology, Cincinnati Children's Hospital, Cincinnati, OH,_ 2 _Biostatistics, Seattle Children's Hospital, Seattle, WA,_ 3 _Pediatric Cardiology, Seattle Children's Hospital, Seattle, WA_

**(708)** Early versus Late Retransplantation in Pediatric Patients: Risk Factors and Impact on Survival; __ F. Altin1, C. McCracken2, K. Kanter1, B. Alsoufi1, S. R. Deshpande3. 1 _Cardiothoracic Surgery, Emory University, Atlanta, GA,_ 2 _Emory University, Atlanta, GA,_ 3 _Pediatric Cardiology, Emory University Children's Healthcare of Atlanta, Atlanta, GA_

**(709)** Outcomes Following Cardiac Transplantation in Children with High Pre-Transplant Pulmonary Vascular Resistance ; __ T. G. Day, K. O'Malley, J. Juarez, F. Bailey, M. Fenton, M. Burch, J. Simmonds. _Cardiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom_

**(710)** The Primary Diagnosis for Pediatric Heart Transplantation Results in Diminished Heart Rate Response ; __ N. M. Singh, R. S. Loomba, J. R. Kovach, S. J. Kindel. _Pediatric Cardiology, Children's Hospital of Wisconsin, Milwaukee, WI_

**(711)** High Pulmonary Vascular Resistance in Pediatric Heart Transplant Patients and Role of Sildenafil; __ P. Patel1, A. Glumova2, K. LaPorte2, W. T. Mahle3, S. R. Deshpande3. 1 _Emory University, Atlanta, GA,_ 2 _Children's Healthcare of Atlanta, Atlanta, GA,_ 3 _Pediatric Cardiology, Emory University Children's Healthcare of Atlanta, Atlanta, GA_

**(712)** Effect of Thyroid Hormone on Cardiac Function Following Orthotopic Heart Transplantation in Piglets; __ T. S. Kumar1, C. Mathis1, S. Sathanandam2, D. Zurakowski3, S. Subramanian2, J. Allen1, M. Solimine1, L. Berrios1, S. Jackson4, M. Landers4, R. Sullivan4, S. Barnett4, C. Loftis1, L. Price1, J. B. Tansey1, D. Hoskoppal5, C. Knott-Craig1. 1 _Cardiothoracic Surgery, Le Bonheur Children's Hospital, Memphis, TN,_ 2 _Pediatric Cardiology, Le Bonheur Children's Hospital, Memphis, TN,_ 3 _Surgery, Boston Children's Hospital, Boston, MA,_ 4 _Comparative Medicine, University of Tennessee Health Science Center, Memphis, TN,_ 5 _Pathology, University of Tennessee Health Science Center, Memphis, TN_

**(713)** Echocardiographic Measurements of Longitudinal Strain Decrease with the Development of Coronary Vasculopathy in Pediatric Heart Transplant Recipients; __ J. Godown1, W. A. McEachern2, M. W. Stanley1, C. J. Havens1, K. A. Wujcik1, J. H. Soslow1, D. A. Dodd1. 1 _Pediatric Cardiology, Monroe Carell Jr. Children's Hospital, Nashville, TN,_ 2 _Pediatrics, Monroe Carell Jr. Children's Hospital, Nashville, TN_

**(714)** Neutropenia in Pediatric Heart Transplant Recipients; __ K. Rose-Felker1, A. Mukhtar2, M. S. Kelleman3, W. T. Mahle1, S. R. Desphande1. 1 _Department of Pediatrics, Sibley Heart Center Cardiology, Emory University, Atlanta, GA,_ 2 _Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA,_ 3 _Department of Pediatrics, Emory University, Atlanta, GA_

**(715)** Challenges of Heart Transplant in Patients with L-Transposition of the Great Vessels; __ A. Magalski1, S. Beauchamp2, A. Borkon2, A. Kao1, S. Aggarwal2, A. Pak2, J. Wang3, K. Allen2. 1 _Cardiology, Mid America Heart Institute of Saint Luke's Hospital, Kansas City, MO,_ 2 _Cardiovascular Surgery, Mid America Heart Institute of Saint Luke's Hospital, Kansas City, MO,_ 3 _Biostatistics, Mid America Heart Institute of Saint Luke's Hospital, Kansas City, MO_

**(716)** Outcomes After Listing for Heart Transplantation in Pediatric and Young Adult Patients with Hypertrophic Cardiomyopathy: An Analysis of the Scientific Recipient Transplant Registry (SRTR); __ D. Cheong1, D. T. Hsu2, J. M. Lamour2. 1 _School of Medicine, University of Connecticut Health Center, Farmington, CT,_ 2 _Pediatric Cardiology, The Children's Hospital at Montefiore, Bronx, NY_

**(717)** Variability in Tacrolimus Levels Is Associated with Biopsy Proven Rejection in Pediatric Heart Transplant Recipients; __ M. Cousino1, K. Rea1, M. Zamberlan2, J. Jordan1, H. Lim1, D. Peng1, K. Schumacher1. 1 _Pediatrics, C.S. Mott Children's Hospital, Ann Arbor, MI,_ 2 _Cardiac Surgery, C.S. Mott Children's Hospital, Ann Arbor, MI_

**(718)** Pancreatitis Following Paediatric Heart Transplantation; __ T. G. Day1, A. Sylvan2, S. Christoforides1, E. Hannon2, J. Curry2, M. Fenton1, M. Burch1, J. Simmonds1. 1 _Cardiology, Great Ormond Street Hospital for CHildren NHS Foundation Trust, London, United Kingdom,_ 2 _Surgery, Great Ormond Street Hospital for CHildren NHS Foundation Trust, London, United Kingdom_

**(719)** Improving Outcomes of Cardiac Transplantation in Patients with Cavopulmonary Connection; __ L. E. De León1, J. S. Heinle1, E. McKenzie1, C. M. Mery1, L. C. Kane1, W. Dreyer2, S. W. Denfield2, J. F. Price2, A. G. Cabrera2, C. D. Fraser, Jr.1, I. Adachi1. 1 _Division of Congenital Heart Surgery, Texas Children's Hospital; Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX,_ 2 _Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children's Hospital, Houston, TX_

**(720)** Primary Graft Dysfunction After Pediatric Heart Transplant: A Single Center Experience; __ K. Mowers, K. Simpson, P. Eghtesady, O. Petrucci, C. Canter, C. Castleberry. _Washington University School of Medicine, St. Louis, MO_

**(721)** AMR in the Current Era: Clinical, Pathologic, and Immunologic Features in Pediatric Heart Transplant Recipieints; __ D. Drogalis-Kim1, M. J. Hickey2, M. C. Fishbein3, J. C. Alejos1, E. F. Reed2, N. J. Halnon1. 1 _Pediatrics, UCLA, Los Angeles, CA,_ 2 _Immunogenetics Center, Department of Pathology and Laboratory Medicine, UCLA, Los Angeles, CA,_ 3 _Pathology and Laboratory Medicine, UCLA, Los Angeles, CA_

**(722)** Preoperative Recipient Factors Predict Outcome in Pediatric Heart Transplant Recipients Using a Novel Risk Factor Score; __ M. J. O'Connor1, A. C. Glatz1, J. W. Rossano1, R. E. Shaddy1, R. M. Ryan1, C. Ravishankar1, S. Fuller2, T. L. Spray2, C. E. Mascio2, J. W. Gaynor2, K. Y. Lin1. 1 _Division of Cardiology, The Children's Hospital of Philadelphia, Philadelphia, PA,_ 2 _Division of Cardiothoracic Surgery, The Children's Hospital of Philadelphia, Philadelphia, PA_

**(723)** CMV-Specific T-Cell Immunity and CMV NAAT in Assignment of CMV Status in Pediatric SOT Candidates; __ C. Burton1, J. Preiksaitis1, M. Sester2, Y. Tong1, F. Wong1, S. Urschel1. 1 _University of Alberta, Edmonton, AB, Canada,_ 2 _Saarland University, Homburg, Germany_

**(724)** The Safety and Efficacy of Total Lymphoid Irradiation in Pediatric Patients with Progressive Chronic Lung Allograft Dysfunction; __ G. Low1, P. Aurora1, M. Gaze2, N. Muthialu1, H. Spencer1. 1 _Great Ormond Street Hospital, London, United Kingdom,_ 2 _University College Hospital, London, United Kingdom_

**(725)** The Burden of Influenza Infection and Disease in Pediatric Lung Transplant Patients; __ K. C. Hannegan, F. M. Munoz, S. Das, E. Elliott. _Baylor College of Medicine, Houston, TX_

**(726)** Immune Monitoring-Guided Treatment of a Pediatric Patient with Sequential GvHD, Acute Rejection and CMV Infection Following Lung Transplantation; __ C. Falk1, N. Schwerk2, C. Mueller2, I. Tudorache3, W. Sommer3, K. Daeman1, J. Keil1, C. Neudörfl1, G. Hansen2, A. Haverich3, G. Warnecke3. 1 _Institute of Transplant Immunology, IFB-Tx, Hannover Med Sch Hannover Medical School, Hannover, Germany,_ 2 _Department of Pediatric Pneumology, Allergology and Neonatalogy, Hannover Med Sch Hannover Medical School, Hannover, Germany,_ 3 _Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Med Sch Hannover Medical School, Hannover, Germany_

**(727)** Radiologic Evaluation of Adult Lung Allografts Implanted in Growing Pediatric Recipients; __ K. Ohata, T. Chen-Yoshikawa, H. Yamagishi, F. Gochi, R. Okabe, M. Saito, A. Takahagi, H. Motoyama, K. Hijiya, A. Aoyama, H. Date. _Department of Thoracic Surgery, Kyoto University, Kyoto, Japan_

**(728)** Nissen's Fundoplication Is Safe and Prevents Decrease in Forced Expiratory Volume in One Second (FEV1) in Paediatric Lung Transplant Patients; __ R. Pabary1, P. Aurora1, J. Curry2, C. Hulsker2, N. Muthialu1, H. Spencer1. 1 _Department of Paediatric Lung Transplantation, Great Ormond Street Hospital, London, United Kingdom,_ 2 _Department of Paediatric General Surgery, Great Ormond Street Hospital, London, United Kingdom_

**(729)** Determination of Modifiable Risk Factors for Infection in the Early Post Lung Transplant Period for Pediatric Cystic Fibrosis Patients ; __ C. Onyearugbulem, L. Williams, H. Zhu, M. C. Gazzaneo, S. Das, F. Lam, J. A. Coss-bu, F. M. Munoz. _Texas Children's Hospital, Houston, TX_

**(730)** Reduced Use of Intensive Care After Pediatric Lung Transplantation: Influence of Early Extubation; __ C. Brooks1, S. Labarinas2, J. Bujan1, C. Pymento3, J. M. Pena4, E. Melicoff-Portillo1, M. C. Gazzaneo5. 1 _Lung Transplant, Texas Children's Hospital, Houston, TX,_ 2 _Critical Care, Baylor College of Medicine/Texas Children's Hospital, Houston, TX,_ 3 _Critical Care, Texas Children's Hospital, Houston, TX,_ 4 _Critical Care, University Hospital of Maracaibo/University of Zulia, Maracaibo, Venezuela, Bolivarian Republic of,_ 5 _Critical Care/Lung Transplant, Texas Children's Hospital, Houston, TX_

**(731)** Prospective Evaluation of Ventricular Loading Trend in Pediatric Patients with Pulsatile Flow LVAD; __ A. Di Molfetta, R. Iacobelli, G. Grutter, S. Filippelli, G. Perri, F. Iodice, L. Pasquini, P. Guccione, A. Amodeo. _Pediatric Hospital Bambino Gesù, Rome, Italy_

**(732)** Outcomes After First Infection in Adolescents and Young Adults with Ventricular Assist Devices: An Analysis of the PEDIMACS/INTERMACS Database; __ S. Chen1, D. N. Rosenthal1, R. C. Cantor2, B. Hong3, R. D. Jaquiss4, S. R. Auerbach5, K. R. Schumacher6, J. C. Alejos7, B. Das8, C. S. Almond1, P. Egtesady9, J. K. Kirklin10, A. Jeewa11. 1 _Stanford University, Palo Alto, CA,_ 2 _Kirklin Institute for Research and Surgical Outcomes, The University of Alabama at Birmingham,, Birmingham, AL,_ 3 _Seattle Children's Hospital, Seattle, WA,_ 4 _Duke University School of Medicine, Durham, NC,_ 5 _Children's Hospital Colorado Heart Institute, Aurora, CO,_ 6 _C.S. Mott Children's Hospital, Ann Arbor, MI,_ 7 _UCLA Mattel Children's Hospital, Los Angeles, CA,_ 8 _UT South Western Medical Center, Dallas, TX,_ 9 _Washington University School of Medicine, St. Louis, MO,_ 10 _Department of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL,_ 11 _The Hospital for Sick Children, Toronto, ON, Canada_

**(733)** Current Practice of Anticoagulation for Pediatric VAD Therapy - A Multi-Institutional European Survey of the EXCOR Pediatric Investigator Group (EEPIG); __ O. Miera1, K. R. Schmitt1, A. K. Menon2, S. Ersel2, A. Reiprich2, H. Akintürk3, J. Thul3, A. Karimova4, R. Cesnjevar5, Z. Reinhardt6, R. Goldwasser7, B. Heineking8, R. Schramm8, B. Romlin9, A. Kansy10, B. Maruszewski10, E. Sandica11, S. Pawlak12, J. Sliwka12, M. Schweiger13, M. Huebler13, B. Stiller14, T. Fleck14, J. Hoerer15, A. Boet15, C. Medrano16, L. G. Guereta17, A. Amodeo18. 1 _Deutsches Herzzentrum Berlin, Berlin, Germany,_ 2 _Berlin Heart, Berlin, Germany,_ 3 _University Hospital Giessen, Giessen, Germany,_ 4 _Great Ormond Street Hospital, London, United Kingdom,_ 5 _University Hospital Erlangen, Erlangen, Germany,_ 6 _Freeman Hospital, Newcastle Upon Tyne, United Kingdom,_ 7 _Heidelberg University Hospital, Heidelberg, Germany,_ 8 _Ludwig-Maximilians University, Munich, Germany,_ 9 _Queen Silvia's Children's Hospital, Gothenburg, Sweden,_ 10 _The Children's Memorial Health Institute, Warsaw, Poland,_ 11 _Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany,_ 12 _Silesian Center for Heart Diseases, Zabrze, Poland,_ 13 _Zurich Children's Hospital, Zurich, Switzerland,_ 14 _University Heart Center Freiburg, Freiburg, Germany,_ 15 _Marie Lannelongue Surgical Center, Paris, France,_ 16 _Hospital General Universitario Gregorio Marañón, Madrid, Spain,_ 17 _University Hospital La Paz, Madrid, Spain,_ 18 _Bambino Gesù Children Hospital, Rom, Italy_

**(734)** Use of TEG/Platelet Mapping to Dose-Adjust Platelet Inhibitors in Children Supported with the Berlin EXCOR: In Search of a Correlation; __ L. J. May1, X. Liu2, C. Sherwin2, L. Yang3, J. Zhender3, J. Lee3, S. Chen4, D. N. Rosenthal4, C. S. Almond4. 1 _Pediatric Cardiology, University of Utah, Salt Lake City, UT,_ 2 _Pediatrics, Division of Clinical Pharmacology, University of Utah, Salt Lake City, UT,_ 3 _Stanford University, Palo Alto, CA,_ 4 _Pediatric Cardiology, Stanford University, Palo Alto, CA_

**(735)** US Center Variability Surrounding Wait List Inactivation Practices After VAD Implantation in Children; __ J. Murray, B. Kaufman, Y. Zhang, M. Gowen, E. Liu, J. Dykes, P. Shuttleworth, O. Jahadi, V. Yarlagadda, K. Maeda, O. Reinhartz, D. Rosenthal, C. Almond, S. Chen. _Lucile Packard Children's Hospital, Palo Alto, CA_

**(736)** Durable Ventricular Assist Devices for Infants Improve Organ Utilization and Survival; __ B. Sheridan1, J. Brink2, I. Konstantinov2, L. Eastaugh3, G. Callea3, J. Mathew3, M. Cheung3, C. Brizard2, Y. d'Udekem2. 1 _Departments of Cardiology and Intensive Care, The Royal Children's Hospital, Melbourne, Australia,_ 2 _Department of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Australia,_ 3 _Department of Cardiology, The Royal Children's Hospital, Melbourne, Australia_

**(737)** Impact of Left Ventricular Assist Device on End-Organ Function in US Children Awaiting Heart Transplant; __ K. Maeda, O. Reinhartz, Y. Zhang, S. Chen, J. Murray, M. M. Gowen, D. McElhinney, D. N. Rosenthal, J. Dykes, C. Almond. _Stanford University, Stanford, CA_

**(738)** Feasibility and Potential Utility of Three-Dimensional Echocardiography in Pediatric Patients with Ventricular Assist Device; __ J. Spinner1, R. Pignatelli1, I. Adachi2, D. M. Feagin1, S. W. Denfield1, A. G. Cabrera1, J. F. Price1, H. Tunuguntla1, W. J. Dreyer1, A. Jeewa1. 1 _Pediatrics, Baylor College of Medicine, Houston, TX,_ 2 _Surgery, Baylor College of Medicine, Houston, TX_

**(739)** Continuous Flow VAD Support at a Tertiary Pediatric Center: Compared to PediMACS Data; __ I. Adachi1, S. Burki1, D. Horne1, A. Jeewa2, B. Elias1, E. McKenzie1, A. G. Cabrera2, C. E. Bocchini3, W. Dreyer2, S. W. Denfield2, J. F. Price2, C. D. Fraser, Jr.1. 1 _Division of Congenital Heart Surgery, Texas Children's Hospital; Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX,_ 2 _Lillie Frank Abercrombie Section of Pediatric Cardiology, Texas Children's Hospital, Houston, TX,_ 3 _Division of Infectious Diseases, Texas Children's Hospital, Houston, TX_

**(740)** Prevalence of Anemia and Iron Deficiency in Pediatric Patients on Ventricular Assist Devices; __ K. Puri1, A. Jeewa1, I. Adachi2, S. W. Denfield1, A. G. Cabrera1, J. F. Price1, T. J. Humlicek1, W. J. Dreyer1, M. D. Shah3. 1 _Cardiology, Baylor College of Medicine/Texas Children's Hospital, Houston, TX,_ 2 _Congenital Heart Surgery, Baylor College of Medicine/Texas Children's Hospital, Houston, TX,_ 3 _Hematology-Oncology, Baylor College of Medicine/Texas Children's Hospital, Houston, TX_

**(741)** Pediatric Mechanical Circulatory Support with Berlin Heart EXCOR System; Experiences in Single Japanese Pediatric Heart Transplantation Center; __ T. Ueno1, M. Taira2, H. Ozawa2, K. Toda2, T. Kuratani1, Y. Sawa2. 1 _Department of Minimally Invasive Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan,_ 2 _Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Japan_

**(742)** Pilot Study of Warfarin Genotype Polymorphisms in Pediatric Patients with Ventricular Assist Devices; __ F. Iodice1, A. Baban1, A. Di Molfetta1, L. Di Chiara1, A. Novelli2, E. Agolini2, A. Amodeo1, G. Testa1. 1 _Cardiac Surgery and Intensive Care Unit, Children's Hospital Bambino Gesù, Rome, Italy,_ 2 _Laboratory Analysis, Children's Hospital Bambino Gesù, Rome, Italy_

**(743)** Cardiac Predictors of Renal Recovery After Pediatric Left Ventricular Assist Device (LVAD) Implantation; __ C. Chen1, M. E. Montez-Rath2, L. J. May3, K. Maeda4, S. A. Hollander1, D. N. Rosenthal1, S. M. Sutherland5, C. D. Krawczeski1. 1 _Pediatric Cardiology, Stanford University, Palo Alto, CA,_ 2 _Nephrology, Stanford University, Palo Alto, CA,_ 3 _Pediatric Cardiology, University of Utah, Salt Lake City, UT,_ 4 _Pediatric Cardiac Surgery, Stanford University, Palo Alto, CA,_ 5 _Pediatric Nephrology, Stanford University, Palo Alto, CA_

**(744)** Prevalence and Characteristics of Anemia and Hemolysis in Percutaneous Ventricular Assist Devices in a Pediatric Center; __ K. Puri1, A. Jeewa1, S. C. Tume2, I. Adachi3, S. W. Denfield1, A. G. Cabrera1, J. F. Price1, H. P. Tunuguntla1, W. J. Dreyer1, M. D. Shah4. 1 _Cardiology, Baylor College of Medicine/Texas Children's Hospital, Houston, TX,_ 2 _Critical Care Medicine, Baylor College of Medicine/Texas Children's Hospital, Houston, TX,_ 3 _Congenital Heart Surgery, Baylor College of Medicine/Texas Children's Hospital, Houston, TX,_ 4 _Hematology-Oncology, Baylor College of Medicine/Texas Children's Hospital, Houston, TX_

**(745)** Evolution of Mitral Regurgitation in Pulsatile Flow LVAD Patients Less Than 10kg; __ A. Di Molfetta, R. Iacobelli, R. Adorisio, S. Filippelli, G. Perri, G. Testa, P. Guccione, A. Amodeo. _Pediatric Cardiology and Cardiac Surgery, Pediatric Hospital Bambino Gesù, Rome, Italy_

## Junior Faculty Clinical Case Reports

(Coronado D and Foyer)

**Poster Discussants:** Meredith A Brisco, MD MSCE (USA), Marco A Caccamo, DO (USA), Laveena Chhatwani, MD (USA), Robert T Cole, MD (USA), Jennifer Eshelman, PharmD (USA), Laura Frye, MD (USA), Arthur R Garan, MD (USA), Laurent Godinas, MD (Belgium), Ranny Goldwasser, MD (Germany), Heather T Henderson, MD (USA), Hanine Inaty, MD (USA), Claire A Irving, MBChB, MRCPCH, MD (Australia), Manreet Kanwar, MD (USA), Evan P Kransdorf, MD, PhD (USA), Hirsch S Mehta, MD (USA), Rajeev Mohan, MD (USA), Alessandro Palleschi, MD (Italy), Caroline M Patterson, MD (United Kingdom), Lynn R Punnoose, MD (USA), Victor Rossel, MD (Chile), Nitasha Sarswat, MD (USA), Keyur B Shah, MD (USA), Palak Shah, MD, MS (USA), Mitesh V Thakrar, MD (Canada), Himabindu Vidula, MD (USA)

**(746)** Intractable Pulmonary Hemorrhage in a Cardiac Transplant Patient on Sirolimus with an Unexpected Pathologic Finding; __ D. R. Fermin1, J. Becker1, A. Booth1, J. Maleszewski2, B. Edwards2, M. Dickinson1. 1 _Spectrum Health, Grand Rapids, MI,_ 2 _Mayo Clinic, Rochester, MN_

**(747)** A Case of Steroid Refractory Eosinophilic Myocarditis; __ S. Kalantari Tannenbaum, J. Grinstein, S. Adatya, G. Sayer, N. Sarswat, G. H. Kim, N. Uriel. _University of Chicago, Chicago, IL_

**(748)** Transaxillary Ventricular Partitioning Device Implantation To Improve Clinical Symptoms of Chronic Heart Failure - A First in Human Case Report; __ E. K. Harmel, U. Schäfer, N. Schofer, F. Deuschl, D. Reichart, S. Blankenberg, H. Reichenspurner, L. Conradi. _Departments of Cardiac Surgery and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany_

**(749)** LVAD Averted: A Case of Reversible Cardiogenic Shock Due to Acute Fibrin Deposition Across a Tissue Pericardial Valve; __ J. N. Patel1, B. S. Clemson1, A. S. Anderson2, D. T. Pham3. 1 _Cardiology, University of Illinois - Peoria, Peoria, IL,_ 2 _Cardiology, Northwestern Memorial Hospital, Chicago, IL,_ 3 _Cardiac Surgery, Northwestern Memorial Hospital, Chicago, IL_

**(750)** Early Calcineurin Inhibitor Withdrawal in a Young Patient with Renal Failure Results in De-Novo Donor Specific Antibodies Triggering Cardiac Allograft Vasculopathy Post Heart Transplantation; __ J. Tauber1, M. Rybczynski2, F. M. Wagner1, H. Reichenspurner1, M. J. Barten1. 1 _Department of Cardiac Surgery, University Heart Center Hamburg, Hamburg, Germany,_ 2 _Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany_

**(751)** Fatal Steatohepatitis and Vasoplegia After Heart Transplant in an LVAD Patient on Amiodarone; __ P. Suryanarayana1, S. Gregoire1, R. Sobonya2, Z. Khalpey3, S. Lick3, N. Sweitzer1. 1 _Cardiology, University of Arizona, Tucson, AZ,_ 2 _Pathology, University of Arizona, Tucson, AZ,_ 3 _Cardiothoracic Surgery, University of Arizona, Tucson, AZ_

**(752)** Total Artificial Heart Salvage of a Heterotopic Heart Transplant Patient with Chronic Rejection and Biventricular Heart Failure; __ I. D. Salas de Armas, M. H. Akay, S. Nathan, S. Stojanovic, R. Radovancevic, P. Loyalka, B. Kar, I. D. Gregoric. _The University of Texas Health Science Center at Houston, Houston, TX_

**(753)** Unusual Case of Bioptome Perforation in Transplanted Heart: Three-Dimensional Computed Tomography Reconstruction of Superior Vena Cava; __ I. Kim1, J. Oh1, S. Lee2, Y. Youn2, S. Kang1. 1 _Cardiology, Severeance Cardiovascular Hospital, Yonsei University, Seoul, Korea, Republic of,_ 2 _Thoracic and Cardiovascular Surgery, Severeance Cardiovascular Hospital, Yonsei University, Seoul, Korea, Republic of_

**(754)** Cardiac Magnetic Resonance-Established Rejection in a Heart Transplant Recipient with a Negative Myocardial Biopsy: A Case Report; __ G. Poglajen1, R. Zbacnik2, A. Cerar1, P. Berden2, B. Vrtovec1. 1 _Advanced Heart Failure and Transplantation Programme, Dept. of Cardiology, University Medical Center Ljubljana, Ljubljana, Slovenia,_ 2 _Institute of Radiology, University Medical Center Ljubljana, Ljubljana, Slovenia_

**(755)** A Case of Acute on Chronic Myocarditis Due to HHV-6 Infection; __ A. Nguyen, K. Mullane, G. Kim, N. Sarswat, S. Adatya, G. Sayer, N. Uriel. _University of Chicago, Chicago, IL_

**(756)** A Rare Case of a Idiopathic Cardiomyopathy Complicated by Acute Pulmonary Emboli in the Setting of Antiphospholipid Syndrome with Successful Bridge to Heart Transplantation via BIVAD Implantation; __ K. Shah, D. Vucicevic, L. Honoris, A. Baas. _Cardiology, University of California Los Angeles, Los Angeles, CA_

**(757)** EGPA Mediated Eosinophilic Myocarditis with Initial Normal Eosinophil Count with Rapid Progressive Decrease in Cardiac Function; __ K. Carlson. _Cardiology, St. Vincent's Hospital Indianapolis, Indianapolis, IN_

**(758)** Cardiopulmonary Resuscitation, Extracorporeal Life Support, BVAD and Successful Heart Transplantation within 2 Months: A Single Center Case Series in 2 Young, High-Urgent Listed Patients; __ A. Schmidt1, D. Saeed1, A. Mehdiani1, B. Sowinski1, R. Westenfeld2, P. Akhyari1, A. Lichtenberg1, U. Boeken1. 1 _Cardiovascular Surgery, University Hospital, Duesseldorf, Germany,_ 2 _Cardiology, University Hospital, Duesseldorf, Germany_

**(759)** Renal Cell Carcinoma in Identical Twin Brothers Following Heart Transplantation; __ Y. Peled, Y. Har-Zahav, Y. Kassif, Y. Shemesh, D. Freimark, Z. Dotan, J. Lavee. _Sheba Medical Center and Tel Aviv University, Tel Aviv, Israel_

**(760)** De Novo Eosinophilic Myocarditis After Heart Transplantation; __ M. Abdou, A. Hadi, A. Brittsan, M. Caccamo. _Division of Cardiology, Indiana University, Indianapolis, IN_

**(761)** Successful Cardiac Transplantation in a Patient with Familial Hypercholesterolemia Treated with a PCSK9 Inhibitor; __ V. Ton1, E. Feller1, G. Ramani1, T. Trobiano1, A. Asser2, M. McLenon3, Z. Kon3, S. Pham3. 1 _Cardiology, University of Maryland Medical Center, Baltimore, MD,_ 2 _Adventist Healthcare Shady Grove Medical Center, Rockville, MD,_ 3 _Cardiothoracic Surgery, University of Maryland Medical Center, Baltimore, MD_

**(762)** Cardiac Transplantation in a Patient with Situs Inversus Totalis and Congenitally Corrected Transposition; __ N. S. Clarke1, M. Drazner2, M. E. Jessen1, M. Peltz1. 1 _Department of Cardiovascular & Thoracic Surgery, UT Southwestern Medical Center, Dallas, TX, _2 _Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX_

**(763)** Hepatitis C Virus Eradication Early After Combined Orthotopic Heart and Liver Transplantation - Can We Expand the Donor Pool?; __ J. Grinstein, L. Lourenco, H. Te, J. Renz, G. Sayer, G. H. Kim, N. Sarswat, S. Adatya, V. Jeevanandam, N. Uriel. _University of Chicago, Chicago, IL_

**(764)** Spontaneous Remission of Giant Cell in Fulminant Lymphocytic Myocarditis; __ T. Sato1, Y. Ikeda2, O. Seguchi1, Y. Kumai1, K. Kuroda1, H. Sunami1, S. Matsuda3, S. Nakajima1, Y. Matsumoto4, K. Wada3, H. Hata4, M. Yanase1, T. Fujita4, H. Ishibashi-Ueda2, J. Kobayashi4, N. Fukushima1. 1 _Transplantation, National Cardiovascular Center, Osaka, Japan,_ 2 _Pathology, National Cardiovascular Center, Osaka, Japan,_ 3 _Pharmacy, National Cardiovascular Center, Osaka, Japan,_ 4 _Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan_

**(765)** Native Myocardial Embolus to Donor Left Anterior Descending Artery After Total Artificial Heart Explant: A Cautionary Note; __ T. Kazui1, B. T. Larsen2, R. G. Smith3, Z. I. Khalpey1, S. D. Lick1. 1 _Cardiothoracic Surgery, Banner University Medical Center Tucson, Tucson, AZ,_ 2 _Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ,_ 3 _Artificial Heart, Banner University Medical Center Tucson, Tucson, AZ_

**(766)** Amiodarone Induced Pulmonary Toxicity After Orthotopic Heart Transplantation: Possible Synergistic Toxicity of Amphiphilic Drugs; __ P. Gosain, V. Parikh, D. Rinde-Hoffman. _Tampa General Hospital, Tampa, FL_

**(767)** First Successful In Vitro Fertilization (IVF) - Induced Twins Pregnancy Following Heart Transplantation (HTX): Long Term Follow-Up; __ Y. Peled1, Y. Har-Zahav1, Y. Kassif1, Y. Shemesh1, D. Freimark1, D. Zacut2, J. Lavee1. 1 _Sheba Medical Center and Tel Aviv University, Tel Aviv, Israel,_ 2 _Hadassah Medical Center, Jerusalem, Israel_

**(768)** Reversible Vasoconstriction Syndrome Soon After Heart Transplantation; __ Y. Kumai1, O. Seguchi1, K. Wada2, K. Kuroda1, S. Nakajima1, H. Sunami1, T. Sato1, M. Yanase1, Y. Matsumoto3, H. Hata3, T. Fujita3, J. Kobayashi3, N. Fukushima3. 1 _Transplantation, National Cerebral and Cardiovascular Center, Suita-City Osaka, Japan,_ 2 _Pharmacy, National Cerebral and Cardiovascular Center, Suita-City Osaka, Japan,_ 3 _Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita-City Osaka, Japan_

**(769)** Significant Improvement in Cardiac Sarcoidosis with Once Monthly Intravenous Methylprednisolone Infusions; __ R. Cogswell1, D. Shapiro2, D. Perlman3, H. Roukoz1, M. Bhargava3. 1 _Cardiology, University of Minnesota, Minneapolis, MN,_ 2 _Midwest Immunology Clinic, University of Minnesota, Plymouth, MN,_ 3 _Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Minnesota, Minneapolis, MN_

**(770)** Angina Early After Heart Transplant: A Unique Case of a Congenitally Absent LMCA with a Superdominant RCA in the Donor Heart; __ K. K. Jain1, A. Magalski1, T. M. Khumri1, B. A. Austin1, A. Kao1, S. L. Lawhorn1, S. Aggarwal2, J. R. Davis2, K. B. Allen2, V. E. Thompson2, A. M. Borkon2. 1 _Department of Cardiology, St. Luke's Mid America Heart & Vascular Institute, University of Missouri-Kansas City School of Medicine, Kansas City, MO, _2 _Department of Cardiothoracic/Vascular Surgery, St. Luke's Mid America Heart & Vascular Institute, Kansas City, MO_

**(771)** Increase in Lung Fluid Content in Response to Milrinone Therapy - Insights into the Activity of Milrinone Using ReDS Technology; __ S. Kalantari, J. Grinstein, G. Sayer, G. H. Kim, N. Sarswat, S. Adatya, N. Uriel. _University of Chicago, Chicago, IL_

**(772)** A Robot to Diagnosis Cardiac Tumors; __ B. H. Trachtenberg, R. Araujo-Gutiérrez, M. Valderrábano. _DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, TX_

**(773)** Longest Duration of Successful Recycled Cardiac Allograft in Intermediate Donor; __ T. Pollema1, H. Tran2, E. Adler2, V. Pretorius1. 1 _Division of Cardiovascular and Thoracic Surgery, University of California San Diego, LA Jolla, CA,_ 2 _Division of Cardiology, University of California San Diego, LA Jolla, CA_

**(774)** Catheter Ablation of Early Native and Late Donor Atrial Arrhythmias After Cardiac Transplantation; __ K. Limmer1, C. A. Athill2, L. Hazard3, K. Ortiz3, P. M. Hoagland4. 1 _Cardiothoracic Surgery, Sharp Memorial Hospital, San Diego, CA,_ 2 _Electrophysiology, Sharp Memorial Hospital, San Diego, CA,_ 3 _Heart Transplant/LVAD, Sharp Memorial Hospital, San Diego, CA,_ 4 _Cardiology, Transplant, Sharp Memorial Hospital, San Diego, CA_

**(775)** HeartWare Left Ventricular Assist Device (HVAD) Inflow Canula Obstruction Caused by Strep Gordonii Endocarditis; __ B. A. Smith1, S. Mitter2, K. Ghafourian2, J. Wilcox2, J. Rich2, A. Anderson2, D. Pham3, E. Vorovich2. 1 _Northwestern Memorial Hospital, Chicago, IL,_ 2 _Division of Cardiology, Northwestern Memorial Hospital, Chicago, IL,_ 3 _Cardiac Surgery, Northwestern Memorial Hospital, Chicago, IL_

**(776)** Left-Ventricular Assist Device Implantation and Radiofrequency Ablation for Ventricular Arrythmia in a Patient with Prior Transcatheter Aortic Valve Replacement; __ V. Garibyan, A. Bitar, R. Mohan, A. Srivastava. _Advanced Heart Failure, Scripps La Jolla, La Jolla, CA_

**(777)** Once Muscles Twitch, It's Time for Catecholamine Switch; __ A. Z. Turk1, L. Tirpaeck1, E. Khan1, F. Katsikeris1, V. A. Grewal1, S. Shaikh1, K. Maqsood2, D. Landry3, J. Hernandez-Montfort4. 1 _Internal Medicine, Baystate Medical Center, Springfield, MA,_ 2 _Cardiology, Baystate Medical Center, Springfield, MA,_ 3 _Nephrology, Baystate Medical Center, Springfield, MA,_ 4 _Cardiology and Advanced Heart Diseases, Baystate Medical Center, Springfield, MA_

**(778)** Combined Heart and Kidney Transplantation in MELAS Syndrome; __ J. Dumfarth1, M. Kofler1, G. Pölzl2, D. Höfer1, S. Eschertzhuber3, K. Kienzl-Wagner4, M. Grimm1, H. Antretter1. 1 _Dep. for Cardiac Surgery, University Clinic Innsbruck, Innsbruck, Austria,_ 2 _Dep. for Cardiology, University Clinic Innsbruck, Innsbruck, Austria,_ 3 _Dep. for Anesthesia, University Clinic Innsbruck, Innsbruck, Austria,_ 4 _Dep. for General Surgery, University Clinic Innsbruck, Innsbruck, Austria_

**(779)** First in Human Robotic Assisted Myocardial Biopsy to Diagnose Cardiac Sarcoidosis; __ A. Bhimaraj, M. Valderrabano. _Cardiology, Houston Methodist Hospital, Houston, TX_

**(780)** Combined Heart-Lung Transplantation for Recurrent Aorto-Mitral Endocarditis; __ M. B. Connellan, K. Dhital, P. Jansz, P. Spratt, E. Granger. _Department of Cardiothoracic Surgery, St. Vincent 's Hosp, Sydney, Australia_

**(781)** Eculizumab in Pediatric Cardiac Antibody Mediated Rejection; __ D. Nandi1, P. Baker2, H. Missler1, L. Fisher1, R. J. Gajarski1, C. M. Phelps1. 1 _The Heart Center, Nationwide Children's Hospital, Columbus, OH,_ 2 _Department of Pathology, Nationwide Children's Hospital, Columbus, OH_

**(782)** Where There Is Pus There Is Steel: An Unusual Complication Post Heart Transplant; __ J. G. Duero Posada, Y. Moayedi, M. Alhussein, S. M. Kozuszko, A. K. McDiarmid, J. Alvarez, T. Yau, S. Husain, M. V. Badiwala, H. J. Ross. _Medicine, University of Toronto, Toronto, ON, Canada_

**(783)** Improved Muscle Strength and Quality of Life After Resistance Training in a Patient with Continuous Flow Left Ventricular Assist Device; __ E. P. Tigges1, S. Schmidt1, M. J. Barten2, S. Capel3, H. Grahn1, S. Blankenberg1, H. Reichenspurner2, M. Rybczynski1. 1 _Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany,_ 2 _Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany,_ 3 _Athletic Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany_

**(784)** Perforation of a HeartMate II Outflow Graft; __ M. Kawabori, C. Kurihara, W. E. Cohn, A. B. Civitello, O. H. Frazier, J. A. Morgan. _Texas Heart Institute, Baylor College of Medicine, Houston, TX_

**(785)** Right Ventricular Pressures Monitoring During Cardiac Surgery; __ K. P. Mody1, A. Chiricolo2, G. P. Siroky1, C. D. Maulion1, D. B. Iyer1, J. L. Almendral1, J. Feliberti1, G. Batsides3. 1 _Cardiology, Robert Wood Johnson University Hospital, New Brunswick, NJ,_ 2 _Anesthesia, Robert Wood Johnson University Hospital, New Brunswick, NJ,_ 3 _Cardiothoracic Surgery, Robert Wood Johnson University Hospital, New Brunswick, NJ_

**(786)** Fighting the Flail Leaflet; __ D. M. Mooney1, K. Rick2, R. Kociol2, E. W. Grandin2. 1 _Advanced Heart Failure, Tufts University Medical Center, Boston, MA,_ 2 _Advanced Heart Failure, Beth Israel Deaconess Medical Center, Boston, MA_

**(787)** Hemodynamic Optimization via Ramp Study for Treatment of Elevated Defibrillation Threshold; __ J. D. Moss1, E. E. Flatley1, G. H. Kim1, N. Sarswat1, S. Adatya1, T. Ota2, G. Sayer1, V. Jeevanandam2, N. Uriel1. 1 _Section of Cardiology, University of Chicago, Chicago, IL,_ 2 _Cardiothoracic Surgery, University of Chicago, Chicago, IL_

**(788)** The Sea Captain's LVAD: The Story of an Insidious Source of Device Thrombosis; __ L. H. Stein1, S. Zarafshar2, D. Banerjee2, R. Ha1. 1 _Department of Cardiothoracic Surgery, Stanford University, Stanford, CA,_ 2 _Department of Cardiovascular Medicine, Stanford University, Stanford, CA_

**(789)** Myasthenia Crisis Complicated by Cardiogenic Shock: Bridge to Recovery with Extracorporeal Membrane Oxygenation; __ J. H. Kim1, C. S. King2, G. Banez-Sese3, L. P. Ryan4, P. Shah5. 1 _Virginia Commonwealth University, Richmond, VA,_ 2 _Medical Critical Care Service, Inova Fairfax Hospital, Falls Church, VA,_ 3 _Inova Pathology Institute, Inova Fairfax Hospital, Falls Church, VA,_ 4 _Cardiac Vascular and Thoracic Surgery Associates, Falls Church, VA,_ 5 _Heart Failure and Transplant Program, Inova Heart and Vascular Institute, Falls Church, VA_

**(790)** In-Vivo Pressure Differential Measurement of an Occluded LVAD Outflow Graft; __ K. J. Mesa1, K. Ihnken1, H. Smith1, D. Sato1, S. Logani1, T. B. Icenogle1, V. Kapustin2, L. Passey1, A. Coletti1. 1 _Mechanical Circulatory Support, Providence Sacred Heart Medical Center, Spokane, WA,_ 2 _Cardiology, Providence Sacred Heart Medical Center, Spokane, WA_

**(791)** Left Anterior Descending Artery Thrombosis in a Patient with a Descending Aortic Left Ventricular Assist System Cannulation; __ S. Mitter, B. Smith, J. Wilcox, J. Rich, D. Pham, A. Anderson, E. E. Eorovich, K. Ghafourian. _Northwestern University, Chicago, IL_

**(792)** Long-Term RVAD Support in an Adult with Pulmonary Atresia and Intact Ventricular Septum; __ J. Hermsen1, A. Stempien-Otero2, K. K. Stout2, E. D. Verrier1, C. Mahr3, N. A. Mokadam1. 1 _Surgery, University of Washington, Seattle, WA,_ 2 _Medicine, University of Washington, Seattle, WA,_ 3 _Meicine, University of Washington, Seattle, WA_

**(793)** Persistent Right Ventricular Failure and Mitral Regurgitation in a Patient with a Left Ventricular Outflow Graft Thrombus; __ S. S. Mitter, B. A. Smith, K. Ghafourin, J. E. Wilcox, J. Rich, D. Pham, A. S. Anderson, E. Vorovich. _Northwestern University, Feinberg School of Medicine, Chicago, IL_

**(794)** Safety and Efficacy of an Impella Supported Open Cholecystectomy; __ G. P. Siroky1, C. D. Maulion1, D. B. Iyer1, J. L. Almendral1, K. P. Mody1, G. Batsides2. 1 _Cardiology, Rutgers - Robert Wood Johnson University Hospital, New Brunswick, NJ,_ 2 _Cardiothoracic Surgery, Rutgers - Robert Wood Johnson University Hospital, New Brunswick, NJ_

**(795)** Paranormal Activity: Para-Esophageal/Gastric Hemorrhage in a Patient with a HeartMate II LVAD; __ A. Sleder, A. Ravichandran. _St. Vincent Hospital, Indianapolis, IN_

**(796)** Successful Delivery in a Patient with LVAD and Unplanned Pregnancy; __ M. Y. Jan1, I. Wang2, T. C. Wozniak3, Z. A. Hashmi4, M. Hadi5, M. A. Caccamo6, J. Pickrell7, E. Gleissner7, L. Dungy-Poythress8. 1 _Internal Medicine, Indiana University School of Medicine, Indianapolis, IN,_ 2 _Surgery, Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, IN,_ 3 _IU Health Physicians Cardiovascular Surgeons, IU Health Methodist Hospital, Indianapolis, IN,_ 4 _Thoracic/Transplant Surgery/ Mechanical Circulatory Support, Indiana University School of Medicine, Indianapolis, IN,_ 5 _Cardiology / Heart Failure, Indiana University School of Medicine, Indianapolis, IN,_ 6 _Cardiology Heart Failure, Indiana University School of Medicine, Indianapolis, IN,_ 7 _Advance Heart & Lung Care Clinic, Indiana University Health Methodist Hospital, Indianapolis, IN, _8 _Maternal-Fetal Medicine, Indiana University School of Medicine, Indianapolis, IN_

**(797)** LVAD Related Aortic Root Thrombus Complicated by Myocardial Infarction Treated with Intra-Aortic Tissue Plasminogen Activator; __ Y. Xu1, L. E. Holton2, J. Abraham3. 1 _Pharmacy, Providence St. Vincent Med Ctr, Portland, OR,_ 2 _Internal Medicine, Legacy Health System, Vancouver, WA,_ 3 _Center for Advanced Heart Disease, Providence Heart and Vascular Institute, Portland, OR_

**(798)** Substrate Guided Surgical Ablation for Ventricular Tachycardia in a Patient Undergoing Left Ventricular Assist Device Implantation; __ N. Akoum1, C. Mahr1, C. S. Masri1, M. Robinson1, J. Beckman1, J. Pal2, J. W. Smith2, N. A. Mokadam2. 1 _Cardiology, University of Washington, Seattle, WA,_ 2 _Cardiothoracic Surgery, University of Washington, Seattle, WA_

**(799)** Use of an Investigational Left Ventricular Assist Device Through a Left Thoracotomy Approach in a Patient with Complex Congenital Heart Disease; __ H. Ilias Basha, K. Takeda, H. Takayama, J. Ginns, N. Persaud, M. F. Pineda, M. Flannery, V. K. Topkara, M. Yuzefpolskaya, P. C. Colombo, Y. Naka, A. R. Garan. _Columbia University, New York, NY_

**(800)** A Case Report of Total Artificial Heart Implantation for Biventricular Failure Due to Eosinophilic Myocarditis; __ A. Critsinelis, C. Kurihara, M. Kawabori, K. A. Heck, W. E. Cohn, A. B. Civitello, O. H. Frazier, J. A. Morgan. _Texas Heart Institute, Division of Cardiothoracic Transplant and Assist Devices, Baylor College of Medicine, Houston, TX_

**(801)** A Successful Conversion from Heartmate II to Heartware Continuous-Flow Mechanical Assist Device in a Pediatric Patient with Pump Thrombosis; __ N. Alami Laroussi1, D. N. Rosenthal1, J. Murray1, O. Reinhartz2, K. Maeda2. 1 _Pediatric Cardiology, Lucile Packard Children's, Stanford University, Palo Alto, CA,_ 2 _Pediatric Cardiovascular Surgery, Lucile Packard Children's, Stanford University, Palo Alto, CA_

**(802)** Concomitant Tricuspid Valve Repair and Left Ventricular Assist Device ( LVAD) Implantation Using the Technique in Patient with Severe Tricuspid Regurgitation; __ A. Badiye1, A. Ghodsizad1, M. Loebe2. 1 _Miami Transplant Institute, University of Miami Miller School of Medicine, Miramar, FL,_ 2 _Miami Transplant Institue, University of Miami Miller School of Medicine, Miami, FL_

**(803)** Impella RP Supported VT Ablation Following HeartMate II Implantation; __ C. D. Maulion1, J. Xu2, W. J. Kostis1, D. Saluja1, K. Mody1, G. Batsides3, D. Iyer1, J. Almendral1. 1 _Cardiology, Rutgers Robert Wood Johnson, New Brunswick, NJ,_ 2 _Internal Medicine, Rutgers Robert Wood Johnson, New Brunswick, NJ,_ 3 _Cardiothoracic Surgery, Rutgers Robert Wood Johnson, New Brunswick, NJ_

**(804)** Distal Limb Perfusion: Cannualtion of Low Superficial Femoral Artery (SFA) for Perfusion Cannula Placement in Patients on Peripheral Venoarterial Extracorporeal Membrane Oxygenation; __ A. Ghodsizad MD, PhD1, M. Loebe MD, PhD2. 1 _Department of Cardiac Surgery, Hershey, PA,_ 2 _Department of Cardiac Surgery, University of Miami, FL_

**(805)** Application of ECCO2R After Rescue VV ECMO Implantation Following Pneumonectomy as Treatment for Narcotizing Pneumonia; __ A. Ghodsizad, B. Forsberg, I. Shulman, S. Chapparo, N. Brozzi, P. Rusconi, J. Bauerlein, A. Badiye, M. Loebe. _University of Miami, Department of Surgery, Miami Transplant Institute, Miami, FL_

**(806)** Autonomic Failure Following Continuous Flow Left Ventricular Assist Device Implantation; __ N. C. Sharma1, D. Chew2, S. Raj1. 1 _Cardiology, Libin Heart Institute, Calgary, AB, Canada,_ 2 _Cardiology, Libin Cardiovascular Institute of Alberta, Calgary, AB, Canada_

**(807)** Successful Treatment of Giant-Cell Myocarditis Complicated by Heparin-Induced Thrombocytopenia; __ J. P. Coveliers, D. De Bock, I. Rodrigus. _Cardiac Surgery, Antwerp University, Edegem, Belgium_

**(808)** Biventricular Standstill in a Patient with Left Ventricular Assist Device; __ C. Teoh1, K. Ho1, L. Louis Teo1, K. David Sim1, T. Tan2, S. Cumaraswamy2, K. Kerk3, C. Lim1. 1 _Cardiology, National Heart Centre, Singapore, Singapore,_ 2 _Cardiothoracic Surgery, National Heart Centre, Singapore, Singapore,_ 3 _Mechanical Circulatory Support, HL Unit, National Heart Centre, Singapore, Singapore_

**(809)** Unusual Life-threatening Complication in a Left Ventricular Assist Device Recipient; __ P. S. Joy, H. Ayinde, M. C. Giudici, V. Cotarlan. _University of Iowa, Iowa City, IA_

**(810)** Successful Implantation of Left Ventricular Assist Device for Cardiogenic Shock Secondary to Left Ventricular Non-Compaction; __ K. Balsara1, M. Ogawa1, A. Bierhals2, J. Vader3, G. Ewald3, L. Jolliff1, M. Pasque1, M. Masood1, A. Itoh1. 1 _Surgery, Washington University in St Louis, St Louis, MO,_ 2 _Radiology, Washington University in St Louis, St Louis, MO,_ 3 _Cardiology, Washington University in St Louis, St Louis, MO_

**(811)** Utilization of VenoVenous ECMO with Atrial Septostomy as a Strategy for Bridge to Lung Transplant in a Patient with Pulmonary Arterial Hypertension; __ K. Morris1, D. Gutteridge2, D. Roe2, T. Wozniak3, Z. Hashmi3, M. Caccamo4. 1 _Indiana University School of Medicine, Indianapolis, IN,_ 2 _Division of Pulmonary and Critical Care, Indiana University School of Medicine, Indianapolis, IN,_ 3 _Division of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, IN,_ 4 _Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, IN_

**(812)** Continuous Flow Left Ventricular Assist Device Implantation Concomitant with Aortic Root and Valve Replacement; __ M. Bazavan1, H. Keshmiri2, A. Andrade1, T. Suboc1, G. Bhat1, S. Pauwaa1, G. Macaluso1, P. Pappas1, A. Tatooles1, M. Dia1, W. Cotts1. 1 _Advocate Christ Medical Center, Oak Lawn, IL,_ 2 _Advocate Illinois Masonic Medical Center, Chicago, IL_

**(813)** Biventricular Impella in a Patient with Biventricular Failure Post Mitral Valve Repair; __ C. D. Maulion1, G. Batsides2. 1 _Cardiology, Rutgers Robert Wood Johnson, New Brunswick, NJ,_ 2 _Cardiothoracic Surgery, Rutgers Robert Wood Johnson, New Brunswick, NJ_

**(814)** The Mysterious Case of the Failing Total Artificial Heart (TAH) Drivers; __ L. Honoris, D. Vucicevic, A. Salimbangon, A. Chang, E. Moreno, J. Creaser, D. Rourke, K. Whalen, E. Vandenbogaart, J. Fuentes, J. Smith, A. Baas, M. Cadeiras, D. Cruz, A. Nasir, M. Kwon, R. Shemin, Y. Geng, A. Kassardjian, G. Fishbein, M. Deng, E. DePasquale. _Cardiology, University of California, Los Angeles, Los Angeles, CA_

**(815)** Can a Left Ventricular Assist Device Cause Autotriggering of a Mechanical Ventilator?; __ J. D. Plamenac1, J. Kumar1, D. Edmundowicz2, Y. Toyoda3, R. Alvarez2, E. Hamad2. 1 _Internal Medicine, Temple University Hospital, Philadelphia, PA,_ 2 _Section of Cardiology, Temple University Hospital, Philadelphia, PA,_ 3 _Cardiovascular Surgery, Temple University Hospital, Philadelphia, PA_

**(816)** A Case of Long-Affecting Pulmonary Arterial Hypertension Associated with Systemic Sclerosis Who Showed Hemodynamic Improvement with Immunosuppressive Therapy; __ A. Saito, M. Hatano, S. Minatsuki, H. Maki, I. Komuro. _The University of Tokyo Hospital, Tokyo, Japan_

**(817)** Pulmonary Hypertension and Hereditary Hemorrhagic Telangiectasia: Importance of the Hemodynamic Evaluation; __ T. Weitsman, T. Hasin, G. Weisz. _Cardiology, Shaare Zedek Medical Center, Jerusalem, Israel_

**(818)** WITHDRAWN

**(819)** Peripheral Pulmonary Artery Stenosis Treated as Idiopathic Pulmonary Arterial Hypertension for 10 Years: A Case Report; __ G. Numata1, M. Hatano1, S. Minatsuki1, E. Amiya1, H. Maki1, M. Watanabe1, H. Matsubara2, I. Komuro1. 1 _Department of Cardiovascular Medicine, The University of Tokyo Hospital, Tokyo, Japan,_ 2 _Department of Cardiovascular Medicine, Okayama Medical Center, Okayama, Japan_

**(820)** Ease the Squeeze! A Case of Partial Anomalous Pulmonary Venous Return (PAPVR); __ H. Fakih1, S. Daouk1, R. Helton2, A. Ataya1, J. Wynne1. 1 _Pulmonary Critical Care, University of Florida, Gainesville, Gainesville, FL,_ 2 _Internal Medicine, University of Florida, Gainesville, Gainesville, FL_

**(821)** Clearance of Hepatitis C Viremia Prior to Lung Transplantation; __ A. E. Shafii, M. Baz. _Surgery, University of Kentucky, Lexington, KY_

**(822)** A Case of Partial Anomalous Pulmonary Venous Return During Lung Donor Recovery; __ A. Mattar, J. Lin, A. Chang, W. Lynch, P. Carrott, R. Reddy, K. Lagisetty. _Thoracic Surgery, University of Michigan, Ann Arbor, MI_

**(823)** Lung Re-Transplantation for Recurrent Lymphangionleiomyomatosis in a Premenopausal Recipient: A Case Report; __ Y. Shikatani1, S. Sugimoto1, S. Otani2, T. Kurosaki2, K. Miyoshi1, M. Yamane1, S. Miyoshi1, T. Oto2. 1 _Department of General Thoracic Surgery, Okayama University Hospital, Okayama, Japan,_ 2 _Organ Transplant Center, Okayama University Hospital, Okayama, Japan_

**(824)** Monocular Blindness Post Lung Transplant; __ J. Lee, M. Lindner, N. Holder, C. Migliore, P. Patel, H. Seethamraju. _Newark Beth Israel Medical Center, Newark, NJ_

**(825)** Use of Arterial Stenting to Relieve Post-Transplant Left Main Pulmonary Artery Obstruction; __ R. M. Hasson Charles1, J. P. Cheatham2, A. L. Pope-Harman3, C. J. Daniels2, B. A. Whitson1. 1 _Cardiothoracic Surgery, The Ohio State Univeristy, Columbus, OH,_ 2 _Interventional Cardiology, Nationwide Childrens Hospital, Columbus, OH,_ 3 _Pulmonology, The Ohio State Univeristy, Columbus, OH_

**(826)** Post Lung Transplant Chylothorax Effectively Treated with Thoracic Duct Embolization ; __ D. J. Franco-Palacios1, A. W. Brown1, C. King1, F. S. Nunes1, A. Mahajan1, S. Khandhar1, A. Venbrux2, O. A. Shlobin1. 1 _Advance Lung Disease and Transplant, Inova Fairfax Hospital, Falls Church, VA,_ 2 _Interventional Radiology, The George Washington University Hospital, Washington, DC_

**(827)** Right Ventricular Outflow Tract Reconstruction During Lung Transplantation; __ S. M. Bell1, J. Javidfar2, M. G. Hartwig1, J. C. Haney1, M. A. Daneshmand1. 1 _Surgery, Duke Univ Med Ctr, Durham, NC,_ 2 _Surgery, Emory University, Atlanta, GA_

**(828)** Successful Long-Term Outcome After Lung Transplant Using Donor Intubated for More Than Ten Months; __ S. Tanaka, K. Miyoshi, T. Kurosaki, S. Otani, S. Sugimoto, M. Yamane, T. Oto. _Department of Thoracic Surgery, Organ Transplant Center, Okayama University Hospital, Okayama, Japan_

**(829)** Once Daily LCP-Tacrolimus in a Cystic Fibrosis Lung Transplant Recipient; __ A. T. Logan1, A. Brueckner1, T. Haddad2. 1 _Department of Pharmacy, Tampa General Hospital, Tampa, FL,_ 2 _Department of Pulmonary Critical Care, Tampa General Hospital, Tampa, FL_

**(830)** Tracheal Bronchus in Donor Lungs: A Technical Challenge; __ S. Tokman1, R. Serrone2, M. A. Smith3, A. Hashimi3, A. Omar1, R. Walia1, R. M. Bremner3. 1 _Advanced Lung Disease, Norton Thoracic Institute, St. Joseph Hospital and Medical Center, Phoenix, AZ,_ 2 _Department of General Surgery, St. Joseph Hospital and Medical Center, Phoenix, AZ,_ 3 _Division of Thoracic Surgery, Norton Thoracic Institute, St. Joseph Hospital and Medical Center, Phoenix, AZ_

**(831)** Atypical Hemolytic Uremic Syndrome: An Intraoperative Complication of Lung Transplantation; __ V. Rusanov1, N. S. Sharma1, C. W. Hoopes2, C. R. Baker3, V. G. Valentine1, K. M. Wille1. 1 _Division of Pulmonary, Allergy & Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, _2 _Department of Surgery, Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL,_ 3 _Critical Care, University of Alabama at Birmingham Hospital, Birmingham, AL_

**(832)** Complications Following Lung Transplantation in a Patient with Short Telomere Syndrome; __ C. Naik, M. Morrell. _Pulmonary, Allergy and Criticl Care Medicine, University of Pittsburgh, Pittsburgh, PA_

**(833)** Diaphragmatic Suspension, a Technique To Overcome Severe Size Mismatch in Lung Transplantation; __ M. H. Ahmed1, W. N. Saleh1, I. Y. Nizami2, S. M. Ahmed2, K. M. Alkattan3. 1 _Thoracic Surgery, King Faisal Specialist Hospital And Research Centre, Riyadh, Saudi Arabia,_ 2 _Organ Transplant Centre, King Faisal Specialist Hospital And Research Centre, Riyadh, Saudi Arabia,_ 3 _Alfaisal University, Riyadh, Saudi Arabia_

**(834)** Severe Primary Graft Failure in Lung Recipients That Required ECMO Had High Level of Donor Derived Cell Free DNA; __ I. Timofte1, S. Agbor-Enoh2, A. Iacono1, J. Orens3, P. Shah3, S. Gorham2, K. Bhatti2, A. Marishta2, M. Jang2, Y. Yang2, U. Fideli2, I. Tunc2, J. Zhu2, S. D. Nathan4, A. W. Brown4, S. Pham1, H. Valantine2. 1 _UMMC, Baltimore, MD,_ 2 _NIH, Bethesda, MD,_ 3 _JHU, Baltimore, MD,_ 4 _Inova, Falls Church, VA_

**(835)** Multi-Stage Approach to Lung Transplantation in a Cystic Fibrosis Patient with Superior Vena Cava Occlusion and Patent Foramen Ovale; __ M. Thomas, R. Agnew, K. Landolfo. _Cardiothoracic Surgery, Mayo Clinic, Jacksonville, FL_

**(836)** Successful Management of Hyperammonemia Syndrome Post Lung Transplantation Syndrome Post Lung Transplantation; __ A. Y. Kamel1, H. Fakih2, S. Daouk2, J. Salgado2, S. Chandrashekaran2, J. Ashton1, D. Driscoll3, G. Maegawa3, T. Machuca4, A. M. Emitazjoo2. 1 _Department of Pharmacy, University of Florida, Gainesville, FL,_ 2 _Division of Pulmonary, Critical Care & Sleep Medicine, University of Florida, Gainesville, FL, _3 _Division of Genetics and Metabolism, University of Florida, Gainesville, FL,_ 4 _Division of Cardiothoracic Surgery, University of Florida, Gainesville, FL_

**(837)** Lung Transplantation for Kartagener Syndrome: Technical Aspects and Morphological Changes of the Transplanted Lungs; __ H. Yamamoto, S. Sugimoto, S. Otani, T. Kurosaki, K. Miyoshi, M. Yamane, S. Miyoshi, T. Oto. _Department of Thoracic Surgery, Organ Transplant Center, Okayama University Hospital, Okayama, Japan_

**(838)** Healing the Broken Heart Following Lung Transplant; __ S. Kapadia1, A. Kharod2, A. Logan3, R. Hooker4, D. Weill1, K. Patel1. 1 _Department of Pulmonary, Critical Care, and Transplant, University of South Florida, Tampa, FL,_ 2 _Department of Cardiovascular Disease, University of South Florida, Tampa, FL,_ 3 _Department of Pharmacy, University of South Florida, Tampa, FL,_ 4 _Department of Cardiothoracic Surgery, University of South Florida, Tampa, FL_

**(839)** A 26-Year Survivor of Heart-Lung Transplant: Complications of Chronic Immunosuppression; __ E. G. Jernigan, V. J. Gonzalez, J. M. Long, J. S. Nelson. _University of North Carolina School of Medicine, Chapel Hill, NC_

**(840)** New Approach for Bridge to Lung Transplant in the Candidates Who Are Not Able to Tolerate Peripheral Venovenous Extracorporeal Membrane Oxygenation; __ T. Yoshizumi1, S. H. Brann1, S. Keshavamurthy1, J. Gomez-Abraham1, M. A. Kashem1, K. Minakata1, F. Cordova2, Y. Toyoda1. 1 _Cardiovascular Surgery, Temple University, Philadelphia, PA,_ 2 _Thoracic Medicine and Surgery, Temple University, Philadelphia, PA_

**(841)** Antibody-Mediated Rejection Associated with Antecedent Cytomegalovirus Pneumonitis in a Lung Allograft Recipient; __ Y. Im, M. Z. Askar, G. S. Schwartz, D. P. Mason, R. R. Rosenblatt, K. A. Ausloos, P. S. Garcha, J. M. Gulleyardo, H. J. Huang, T. Sam. _Baylor University Medical Center, Dallas, TX_

**(842)** Applying Positive End-Expiratory Pressure Titration During Ex-Vivo Lung Perfusion: One Way of Recruiting Clinically Rejected Donor Lungs; __ K. S. Ayyat, H. Niikawa, T. Okamoto, K. R. McCurry. _Cleveland Clinic Foundation, Cleveland, OH_

**(843)** Hyperammonemia in Lung Transplant Patients; __ H. M. Gonzalez Bonilla1, A. Goodarzi2, A. S. Siddiqui2, M. Pendurthi3, T. S. Kaleekal2. 1 _Medicine, Houston Methodist Hospital, Houston, TX,_ 2 _Pulmonary and Critical Care Division, Houston Methodist Hospital, Houston, TX,_ 3 _Pulmonary and Critical Care Division, Baylor College of Medicine, Houston, TX_

**(844)** Replacement of Artificial Trachea with New Reconstruction of the Trachea and Bronchial Artery Along with Lung Transplantation; __ A. Kashem1, S. Keshavamurthy1, J. Gomez-Abraham1, T. Yoshizumi1, F. Cordova2, S. Kartik2, A. J. Mamary2, G. Criner2, Y. Toyoda1. 1 _Cardiovascular Surgery, Temple University, Philadelphia, PA,_ 2 _Thoracic and Pulmonary Medicine, Temple University, Philadelphia, PA_

**(845)** Central Canulation for Extracorporeal Circulation in Minimal Invasive Lung Transplantation; __ I. Moneke, S. Wiesemann, B. Passlick, P. von Samson. _Thoracic Surgery, University Hospital Freiburg, Freiburg, Germany_

**(846)** Contemporary Networks of Care: How Eleven Physicians Across Four Subspecialties and Two Countries United to Care for a Critically Ill Twenty-Three-Year-Old Female; __ L. Harper1, J. Grewal2, G. Finlayson3, R. Nador1, M. Kiess2, J. Swiston1, J. Granton4, L. Klein5, T. De Marco5, J. Yee6, J. Golden7, R. Levy1. 1 _Division of Respirology, University of British Columbia, Vancouver, BC, Canada,_ 2 _Division of Cardiology, University of British Columbia, Vancouver, BC, Canada,_ 3 _Division of Critical Care Medicine, University of British Columbia, Vancouver, BC, Canada,_ 4 _Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada,_ 5 _Division of Cardiology, University of California San Francisco, San Francisco, CA,_ 6 _Division of Thoracic Surgery, University of British Columbia, Vancouver, BC, Canada,_ 7 _Division of Respirology, University of California San Francisco, San Francisco, CA_

**(847)** Successful Resolution of Refractory Rejection with Cyclophosphamide in a Lung Transplant Recipient Intolerant to Cell Cycle and Proliferation Signal Inhibitors; __ C. A. Moore, M. R. Pipeling, C. R. Ensor. _University of Pittsburgh, Pittsburgh, PA_

**(848)** Coxsackie B Infection with Multi-Organ Involvement Resulting in Shock; __ K. Hopkins1, M. Abdou2, I. Gradus-Pizlo1, M. Caccamo1, Z. Hashmi3, T. Wozniak3, A. Brittsan1, J. E. Finet1, A. Hadi2. 1 _Department of Medicine, Indiana University, Indianapolis, IN,_ 2 _Division of Cardiology, Indiana University, Indianapolis, IN,_ 3 _Cardiothoracic Surgery, Indiana University, Indianapolis, IN_

**(849)** Novel Outpatient Strategy for Managing Resistant CMV Infection Post Lung Transplant; __ K. Santhanakrishnan, E. Karimi, M. Alaloul, R. Venkateswaran, N. Yonan. _Transplant Department, Wythenshawe Hospital, Manchester, United Kingdom_

**(850)** Paradoxical Reaction of Tuberculosis During Anti-Tuberculosis Therapy in a Heart Transplant Recipient; __ A. Wakamiya1, O. Seguchi2, M. Kumamoto3, Y. Kumai2, H. Sunami2, K. Kuroda2, S. Nakajima2, T. Sato2, M. Yanase2, N. Fukushima2. 1 _Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan,_ 2 _Transplantation, National Cerebral and Cardiovascular Center, Osaka, Japan,_ 3 _Stroke and Cerebrovascular Diseases, National Cerebral and Cardiovascular Center, Osaka, Japan_

**(851)** Invasive Pulmonary Aspergillosis in Tuberculosis Cavitation Successfully Treated by Combined Surgery and Antifungal Therapy in a Heart Recipient; __ P. Avellana, A. Ini, M. Ajzenszlos, D. Radlovachki, S. Belforte, L. Ahualli. _Hospital Cosme Argerich, Buenos Aires, Argentina_

**(852)** Monster Lung Cavity in a Heart Transplant Recipient; __ J. Jahanyar, J. Stephen, A. Sadiqi, P. A. DeValeria, B. W. Hardaway, R. R. Sista, O. E. Pajaro, E. D. Steidley. _Mayo Clinic, Phoenix, AZ_

**(853)** Apical Aneurysm as Acute Manifestation of Chagas' Disease Reactivation After Heart Transplantation - Changing a Paradigm; __ L. L. Trevizan, G. C. Lima, S. Mangini, A. V. Oliveira, R. B. Piveta, F. S. Brito, B. R. Alves, L. T. Pires, J. Xavier Jr, T. G. Merluzzi, R. Poffo, F. Bacal. _Hospital Israelita Albert Einstein, São Paulo, Brazil_

**(854)** Simultaneous Pulmonary Cunninghamella and Nocardia Infections; __ B. Wolf, V. Stosor, M. Angarone, A. Anderson. _Infectious Diseases, Northwestern Memorial Hospital, Chicago, IL_

**(855)** Asymptomatic Disseminated Cryptococcus neoformans Infection in a Lung Transplant Recipient Detected by Surveillance Bronchoscopy; __ R. J. Hadley1, E. T. Murphy2, R. E. Girgis1. 1 _Pulmonary Medicine, Spectrum Health, Grand Rapids, MI,_ 2 _Thoracic Surgery, Spectrum Health, Grand Rapids, MI_

**(856)** Disseminated Adenovirus Infection in Heart and Kidney Transplant; __ K. V. Patel1, J. Xu2, J. Almendral1, K. Mody1, D. Iyer1. 1 _Cardiology, Rutgers - Robert Wood Johnson University Hospital, New Brunswick, NJ,_ 2 _Internal Medicine, Rutgers - Robert Wood Johnson University Hospital, New Brunswick, NJ_

**(857)** Invasive Fungal Pneumonia Due to Aspergillus Terreus After Heart Transplant: To Treat Medically or Surgically?; __ J. Leoni, M. Avila, P. Patel, D. Yip, M. Thomas, J. Hosenpud. _Mayo Clinic, Jacksonville, FL_

**(858)** An Unusual Complication of Sinusitis Following Cardiac Transplantation; __ H. Ilias Basha, B. Scully, S. Whittier, S. Restaino, F. Latif, M. Yuzefpolskaya, P. Colombo, R. Bijou, M. Farr. _Columbia University, New York, NY_

**(859)** Left Ventricle Assisted Device Driveline Infections: The Unusual Suspect; __ G. A. Hernandez1, J. D. Nunez Breton2, J. Simkins Cohen3, S. V. Chaparro1. 1 _Cardiology, University of Miami/Jackson Memorial Hospital, Miami, FL,_ 2 _Internal Medicine, University of Miami/Jackson Memorial Hospital, Miami, FL,_ 3 _Infectious Diseases, University of Miami/Jackson Memorial Hospital, Miami, FL_

**(860)** Severe MMF-related Colon Toxicity in a Pediatric Heart Transplant Patient Following Treated EBV-Associated Tumors; __ J. E. Ryan, M. A. McCulloch, R. R. Davies. _Cardiac Center, AI duPont Hospital for Children/Nemours, Wilmington, DE_

**(861)** Unusual Presentation of Multifocal Cardiac Rhabdomyoma Requiring Orthotropic Heart Transplantation; __ D. Gupta1, D. Rush2, R. M. Bryant1, M. S. Bleiweis1, B. A. Pietra1, F. J. Fricker1. 1 _Congenital Heart Center, Department of Pediatrics, University of Florida, Gainesville, FL,_ 2 _Department of Pathology, University of Florida, Gainesville, FL_

**(862)** Heart Transplantation in Neonatal Marfan Syndrome: Progress in a Rare and Fatal Disease; __ J. A. Laks, O. Honjo, L. Grosse-Wortmann, A. I. Dipchand. _Cardiology, The Hospital for Sick Children, Toronto, ON, Canada_

**(863)** Successful Heart Transplant for Turner's Syndrome and Hypoplastic Left Heart Syndrome: Is Primary Transplant the Answer?; __ D. Gupta, J. Philip, H. V. Vyas, F. J. Fricker, B. A. Pietra, M. S. Bleiweis. _Congenital Heart Center, Department of Pediatrics, University of Florida, Gainesville, FL_

**(864)** Biventricular Pacing in an Infant Following Resection of Large Cardiac Fibroma and Surgical AV Block; __ J. J. Parent, R. K. Darragh, A. C. Kean, M. D. Ayers. _Pediatric Cardiology, Riley Hospital at Indiana University Health, Indianapolis, IN_

**(865)** Pay Me Now or Pay Me Later: A Tale of Two Sensitized Pediatric Heart Transplant Candidates; __ M. Mangiola1, B. Feingold2, D. Magnetta2, S. West2, S. Miller2, M. Zinn2, M. Marrari1, A. Zeevi1. 1 _Univ of Pittsburgh Med Ctr, Pittsburgh, PA,_ 2 _Heart Failure and Transplantation Programs, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA_

**(866)** Pediatric Heart Transplantation from a Donor with Methanol Intoxication; __ H. R. Martinez, J. J. Parent. _Pediatric Cardiology, Riley Hospital for Children, Indianapolis, IN_

**(867)** Left Ventricular Hypertrophy with Pathologic T Wave Inversion in Adolescent African American Athletes: Early Cardiomyopathy or Normal Phenomenon?; __ T. O. Thomas, S. Das, E. A. Frazier, K. R. Knecht. _Pediatrics, Arkansas Children's Hospital, Little Rock, AR_

**(868)** Myocardial Recovery in a Teenager After a Large Anteroseptal Myocardial Infarction: Novel Management with a Temporary Left Ventricular Assist Device; __ L. J. May1, K. M. Molina1, E. Griffiths2, H. S. Magdo1, A. K. Lal1, C. Delgado3, C. H. Selzman4, A. Eckhauser2. 1 _Pediatric Cardiology, Primary Children's Hospital, Salt Lake City, UT,_ 2 _Cardiothoracic Surgery, Primary Children's Hospital, Salt Lake City, UT,_ 3 _Pediatric Critical Care, Primary Children's Hospital, Salt Lake City, UT,_ 4 _Cardiothoracic Surgery, University of Utah, Salt Lake City, UT_

**(869)** Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection in a Two-Year-Old Heart Transplant Patient; __ J. Spinner1, M. A. Balderas2, C. E. Bocchini1, R. A. Luna2, S. W. Denfield1, W. J. Dreyer1, D. Nagy-Szakal1, F. D. Ihekweazu1, T. Savidge2, R. Kellermayer1. 1 _Pediatrics, Baylor College of Medicine, Houston, TX,_ 2 _Pathology and Immunology, Baylor College of Medicine, Houston, TX_

**(870)** Disseminated Adenovirus Infection Successfully Treated with Brincidofivir in a Pediatric Heart Transplant Recipient; __ S. J. Wilkens1, P. T. Thrush1, C. L. Backer2, E. Pahl1. 1 _Pediatric Cardiology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, _2 _Cardiovascular Thoracic Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL_

**(871)** Clinical Variance in Two Sisters with Complex Congenital Heart Disease and Cardiomyopathy Sharing a Homozygous Variant in the CAP2 Gene; __ S. M. Mitchell1, R. Bradshaw2, C. Reddy3, S. Al-Jureidini3, S. Braddock2, M. Willing4, L. Cerny5. 1 _Pediatrics, Saint Louis University School of Medicine-Cardinal Glennon Children's Medical Center, Saint Louis, MO,_ 2 _Medical Genetics, Saint Louis University School of Medicine-Cardinal Glennon Children's Medical Center, Saint Louis, MO,_ 3 _Pediatric Cardiology, Saint Louis University School of Medicine-Cardinal Glennon Children's Medical Center, Saint Louis, MO,_ 4 _Pediatrics, Division of Genetics and Genomic Medicine, Washington University School of Medicine in St. Louis, St. Louis Children's Hospital, Saint Louis, MO,_ 5 _Neonatology, Saint Louis University School of Medicine-Cardinal Glennon Children's Medical Center, Saint Louis, MO_

**(872)** Neurologic Events in Patients with Ventricular Assist Device: Don't Forget the Basics; __ L. D. Glass1, H. Buchholz2, S. Urschel1, C. Cunningham1, P. Holinski3, V. Anand3, J. Conway1. 1 _Pediatric Cardiology, Stollery Children's Hospital, Edmonton, AB, Canada,_ 2 _Cardiac Surgery, Stollery Children's Hospital, Edmonton, AB, Canada,_ 3 _Pediatric Critical Care, Stollery Children's Hospital, Edmonton, AB, Canada_

**(873)** Airway Plaque Presenting After Alteration of Immunosuppression in a Pediatric Patient Remote from Heart Transplantation; __ T. D. Ryan1, M. J. Absalon2, A. de Alarcon3, A. Gupta4, A. Lorts1, L. A. Danziger-Isakov5, C. Chin1. 1 _Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH,_ 2 _Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH,_ 3 _Division of Pediatric Otolaryngology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH,_ 4 _Division of Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH,_ 5 _Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH_

**(874)** HeartWare Ventricular Assist Device as Bridging Therapy for Transplant in 6-Year Old Child with Myocarditis; __ A. Garg1, X. Vilal2, A. Ghodsizad2, M. Loebe2, N. Brozzi2, E. R. Rosenkranz3, P. Rusconi4. 1 _Pediatrics, Jackson Memorial Hospital, Miami, FL,_ 2 _Surgery, Miami Transplant Institute/University of Miami/Miller School of Medicine, Miami, FL,_ 3 _Surgery, University of Miami/Miller School of Medicine, Miami, FL,_ 4 _Pediatrics, Miami Transplant Institute/University of Miami/Miller School of Medicine, Miami, FL_

**(875)** Cardiac Transplantation in a Neonate - First Case in Switzerland and European Overview; __ M. Schweiger1, B. Stiasny1, F. Immer2, C. Buerki1, O. Kretschmar1, H. Dave1, A. Cavigelli-Brunnerb1, M. Schmiady1, V. Cannizzaroe1, O. Kretschmar1, M. Huebler1. 1 _Children's Hospital, Zurich, Switzerland,_ 2 _Swiss Transplant, Bern, Switzerland_

**(876)** Giant Coronary Artery Aneurysms and Heart Failure in Kawasaki Disease Leading to VAD Placement; __ A. Butto1, D. Nandi2, C. E. Mascio3, J. W. Rossano1. 1 _Division of Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA,_ 2 _Cardiology, The Heart Center, Nationwide Children's Hospital, Columbus, OH,_ 3 _Pediatric Cardiothoracic Surgery, Children's Hospital of Philadelphia, Philadelphia, PA_

**(877)** Hypertensive Cardiomyopathy in an Infant : A Diagnostic Challenge; __ P. Patel1, K. Rose-Felker2, H. Viamonte2, W. T. Mahle2, S. R. Deshpande2. 1 _Emory University, Atlanta, GA,_ 2 _Pediatric Cardiology, Emory University Children's Healthcare of Atlanta, Atlanta, GA_

# Poster Session 2

Thursday, April 06, 2017

6:15 PM - 7:15 PM

NOTE: Poster presenters and discussants will be present during the evening poster viewing session from 6:15 PM – 7:15 PM.

## Economics, Ethics, Public Policy

(Coronado Foyer)

**Poster Discussants:** Cristiano Amarelli, MD (Italy), Melanie D Everitt, MD (USA), Kathleen L Grady, PhD, APN, FAAN (USA)

**(878)** Association of Insurance Coverage on the Development of Coronary Allograft Vasculopathy After Pediatric Heart Transplant; __ E. Pruitt1, S. Urschel2, M. D. Everitt3, J. K. Kirklin1, D. C. Naftel1. 1 _University of Alabama at Birmingham, Birmingham, AL,_ 2 _University of Alberta, Edmonton, AB, Canada,_ 3 _Children's Hospital Colorado Heart Institute, Aurora, CO_

**(879)** Socioeconomic Status and Heart Transplantation; __ N. Harati1, A. Iyengar1, E. Adams1, C. Eisenring2, L. Reardon3, M. Deng3, A. Ardehali2, E. DePasquale3. 1 _David Geffen School of Medicine, University of California - Los Angeles, Los Angeles, CA,_ 2 _Department of Cardiac Surgery, University of California - Los Angeles, Los Angeles, CA,_ 3 _Department of Cardiology, University of California - Los Angeles, Los Angeles, CA_

**(880)** The In-Hospital Cost of Heart Transplantation; __ A. Iyengar1, E. Adams1, C. Eisenring2, N. Satou2, L. Reardon3, M. Deng3, R. J. Shemin2, A. Ardehali2, E. DePasquale3. 1 _David Geffen School of Medicine, University of California - Los Angeles, Los Angeles, CA,_ 2 _Department of Cardiac Surgery, University of California - Los Angeles, Los Angeles, CA,_ 3 _Department of Cardiology, University of California - Los Angeles, Los Angeles, CA_

**(881)** Simplification of Cyclosporine a Dosing Strategy to Improve Medication Adherence; __ E. K. Harmel1, M. H. Goldmann1, N. Hasait2, M. Rybczynski3, H. Reichenspurner1, M. J. Barten1. 1 _Department of Cardiac Surgery, University Heart Center Hamburg, Hamburg, Germany,_ 2 _Department of Pharmacology, University Heart Center Hamburg, Hamburg, Germany,_ 3 _Department of Cardiology, University Heart Center Hamburg, Hamburg, Germany_

**(882)** Can Lungs Be Recovered Quickly from First Person Authorized (FPA) Uncontrolled Donation After Circulatory Determination of Death Donors (uDCDDs)? The Law vs Knowledge and Attitudes Among FPA Adults; __ T. M. Egan1, J. Requard III2, T. Edwards3. 1 _Surgery, U. North Carolina Sch Med, Chapel Hill, NC,_ 2 _Lung Banks of America, Chapel Hill, NC,_ 3 _ODUM Institute, U. North Carolina Sch Med, Chapel Hill, NC_

**(883)** Causes and Preventability of Unplanned Rehospitalization Following Lung Transplantation; __ A. Courtwright1, D. Zaleski2, V. Ahya1, C. Bermudez3, N. Blumenthal1, E. Cantu3, J. Christie1, T. Claridge1, M. Crespo1, J. Golato1, D. Hadjiliadis1, E. Hobson1, J. Lee1, M. Molina3, N. Patel1, M. Porteous1, J. Diamond1. 1 _Pulmonary and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA,_ 2 _Good Shepard Penn Partners, Philadelphia, PA,_ 3 _Cardiothoracic Surgery, University of Pennsylvania, Philadelphia, PA_

**(884)** Terminal Withdrawal of ECMO in the ICU: A Retrospective Analysis ; __ N. A. Braus1, P. S. Mueller2, G. J. Schears3. 1 _Pulmonary and Critical Care, Mayo Clinic, Rochester, MN,_ 2 _General Internal Medicine, Mayo Clinic, Rochester, MN,_ 3 _Anesthesiology, Mayo Clinic, Rochester, MN_

**(885)** Subclavian Artery Access Intra-Aortic Balloon Pump (sIABP): An Excellent Value-Based Bridge to Transplant Therapy; __ T. Lammy1, C. Juricek1, V. Kagan1, D. Onsager1, T. Song1, T. Ota1, N. Uriel2, V. Jeevanandam1. 1 _Cardiothoracic Surgery, University of Chicago Medicine, Chicago, IL,_ 2 _Cardiology, University of Chicago Medicine, Chicago, IL_

**(886)** Patient and Clinician Insights for Dissemination and Implementation Planning of a Patient-Centered Decision Aid for Left Ventricular Assist Device (LVAD) Treatment; __ K. M. Kostick1, R. J. Volk2, C. R. Bruce1, S. A. McCurdy3, J. D. Estep4, J. S. Blumenthal-Barby1. 1 _Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX,_ 2 _Department of Health Services Research, The M.D. Anderson Cancer Center, University of Texas, Houston, TX,_ 3 _School of Public Health, University of Texas, Houston, TX,_ 4 _Houston Methodist DeBakey Heart & Vascular Center and J.C. Walter Jr. Transplant Center, Houston Methodist Hospital, Houston, TX_

**(887)** Mechanical Circulatory Support Devices (MSCD) Therapy in the Era of the Affordable Care Act (ACA): National Trends in Hospitalization Costs and In-Hospital Mortality; __ L. Sridharan1, R. Givens1, A. R. Garan1, M. Yuzefpolskaya1, K. Takeda2, H. Takayama1, F. Latif1, J. Haythe1, S. Restaino1, M. Maurer1, D. Mancini3, M. J. Farr1, Y. Naka2, P. Colombo1, V. K. Topkara1. 1 _Cardiology, Columbia University, New York, NY,_ 2 _Cardiothoracic Surgery, Columbia University, New York, NY,_ 3 _Cardiology, Mount Sinai, New York, NY_

**(888)** Destination to Nowhere: The Ethics of Acute Mechanical Circulatory Support; __ V. Kagan1, R. Rose1, H. Costantini1, C. Juricek1, T. Lammy1, T. Ota1, D. Onsager1, S. Adatya2, N. Uriel2, P. Angelos3, V. Jeevanandam1, T. Song1. 1 _Cardiothoracic Surgery, University of Chicago Medicine, Chicago, IL,_ 2 _Cardiology, University of Chicago Medicine, Chicago, IL,_ 3 _General Surgery, University of Chicago Medicine, Chicago, IL_

**(889)** Doing the Math: The Costs of Long Term Mechanical Circulatory Support; __ J. J. Chung1, R. Stetson2, C. W. Chen1, A. C. Gaffey1, J. Rame3, M. A. Acker4, P. Atluri4. 1 _Department of Surgery, University of Pennsylvania, Philadelphia, PA,_ 2 _Corporate Office of Strategic Decision Support, University of Pennsylvania, Philadelphia, PA,_ 3 _Department of Medicine, University of Pennsylvania, Philadelphia, PA,_ 4 _Division of Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA_

**(890)** Building a More Cost-Efficient ECLS Team by Inviting Everyone to the Table; __ R. A. Rose1, R. M. Piech2, V. Kagan2, A. F. Linden3, N. Uriel4, V. Jeevanandum2, T. H. Song2. 1 _ECMO / MCS Services, University of Chicago Medicine, Chicago, IL,_ 2 _Cardiothoracic Surgery, University of Chicago Medicine, Chicago, IL,_ 3 _Pediatric Surgery, University of Chicago Medicine, Chicago, IL,_ 4 _Cardiology, University of Chicago Medicine, Chicago, IL_

## Heart Transplantation

(Regatta Foyer)

**Poster Discussants:** Mark B Connellan, MD, FC(Cardio) (Australia), Eugene C DePasquale, MD (USA), Sitaramesh Emani, MD (USA), Eileen M Hsich, MD (USA), Kiran Khush, MD, MAS (USA), Lucian Lozonschi, MD (USA), Satoshi Saito, MD, PhD (Japan), Daniel B Sims, MD (USA), Mustafa Toma, MD (Canada), Adriana Torres, MD (Colombia), Marian Urban, MD (United Kingdom), Tahir Yagdi, MD (Turkey)

**(891)** The Risk of Naïve vs Memory Patients Awaiting Heart Transplantation: Does It Make a Difference in Post-Transplant Outcomes?; __ J. A. Kobashigawa, N. Reinsmoen, X. Zhang, M. Kittleson, T. Aintablian, J. Mackinnon-Krems, E. Kransdorf, D. Chang, L. Czer, F. Esmailian, J. Patel. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(892)** WITHDRAWN

**(893)** Correlation of the Grades of Antibody-Mediated Rejection to 1-Year IVUS Results After Heart Transplantation; __ J. A. Kobashigawa, M. Kittleson, S. Sana, T. Aintablian, R. Levine, B. Azarbal, D. Geft, D. H. Chang, L. Czer, D. Luthringer, J. Patel. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(894)** High Levels of Galectin 3 in Heart Recipients with a History of Acute Cellular Rejection; __ E. Sarmiento1, M. Sarwal2, T. Sigdel3, Y. Ng4, L. Li5, C. Rodriguez6, Y. Castro7, I. Sousa8, E. Zatarain8, J. Carbone1. 1 _Clinical Immunology, Hospital General Universitario Gregorio Marañon, Madrid, Spain,_ 2 _Division of Multiorgan Transplant, University of California San Francisco, San Francisco, CA,_ 3 _Surgery, School of Medicine, University of California San Francisco, San Francisco, CA,_ 4 _Surgery, University of California San Francisco, San Francisco, CA,_ 5 _Department of Biostatistics, Mount Sinai School of Medicine, New York, NY,_ 6 _Biochemistry, Hospital General Universitario Gregorio Marañon, Madrid, Spain,_ 7 _Pathology, Hospital General Universitario Gregorio Marañon, Madrid, Spain,_ 8 _Cardiology, Hospital General Universitario Gregorio Marañon, Madrid, Spain_

**(895)** The Outcome of Heart Transplant Patients with Hemodynamic Compromise Rejection in the Current Era; __ J. A. Kobashigawa, M. Kittleson, T. Aintablian, D. H. Chang, D. Geft, L. Czer, F. Esmailian, J. Patel. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(896)** WITHDRAWN

**(897)** Can We Use Tissue Doppler Imaging to Screen for Cardiac Allograft Rejection and Coronary Vasculopathy?; __ M. D. Yu1, E. Sampene2, J. Nan1, P. Rahko3, R. Dhingra3. 1 _Department of Medicine, University of Wisconsin, Madison, WI,_ 2 _Department of Biostatistics, University of Wisconsin, Madison, WI,_ 3 _Advanced Heart Failure and Transplant Cardiology, University of Wisconsin, Madison, WI_

**(898)** Human Leucocyte Antigen (HLA) Matching in Heart Transplantation: Impact on Cellular Rejection and Survival?; __ U. Boeken1, A. Albert1, A. Mehdiani1, G. Petrov1, B. Sowinski1, R. Westenfeld2, D. Saeed1, P. Akhyari1, A. Lichtenberg1. 1 _Cardiovascular Surgery, University Hospital, Duesseldorf, Germany,_ 2 _Cardiology, University Hospital, Duesseldorf, Germany_

**(899)** Early Exposure to ISHLT Grade 1R Rejection Reduces Long-Term Mortality in Heart Transplant Recipients Surviving the First Year; __ M. Yin, A. Esmaeeli, A. Morris, D. Gupta, D. Vega, R. Laskar, A. Smith, R. Cole. _Emory University School of Medicine, Atlanta, GA_

**(900)** Variability in Gene Expression Profiling (GEP) Identifies Heart Transplant Recipients at Risk for Acute Cellular Rejection but Not Cardiac Allograft Vasculopathy; __ L. K. Truby, A. R. Garan, R. Givens, K. Takeda, H. Takayama, M. Yuzefpolskaya, S. Restaino, E. Zorn, D. Mancini, P. C. Colombo, Y. Naka, M. Farr, F. Latif, V. K. Topkara. _Columbia University College of Physicians and Surgeons, New York, NY_

**(901)** Utility of Cardiac Magnetic Resonance Imaging (CMR) in the Evaluation of Heart Transplant (HT) Patients with Suspected Rejection; __ D. M. Tehrani, D. Medvedofsky, K. Kawaji, S. Adatya, N. Sarswat, J. Raikhelkar, G. H. Kim, G. Sayer, R. M. Lang, A. R. Patel, N. Uriel. _University of Chicago, Chicago, IL_

**(902)** Acute Cellular Rejection in Heart Transplant Recipients May Not Be Acute After All; __ N. Bassi1, G. Sayer1, L. Benes1, C. Murks2, J. Raikhelkar2, S. Adatya2, G. Kim2, N. Sarswat2, T. Ota3, V. Jeevanandam3, N. Uriel2. 1 _University of Chicago, Chicago, IL,_ 2 _Cardiology, University of Chicago, Chicago, IL,_ 3 _Cardiac Surgery, University of Chicago, Chicago, IL_

**(903)** Early Antibody Mediated Rejection Post Orthotopic Heart Transplantation: A Single Center Experience; __ I. Rajapreyar1, S. Nathan2, A. Ghotra3, M. Nolan2, P. Weeks4, a. Sieg5, B. Kar6, P. Loyalka2, C. Paruthi6, I. Gregoric6. 1 _University of Alabama, Birmingham, Birmingham, AL,_ 2 _University of Texas, Houston, Houston, TX,_ 3 _University of Texas, Houston, Birmingham, AL,_ 4 _Memorial Hermman Hospital, Houston, TX,_ 5 _University of Kentucky, Louisville, KY,_ 6 _University of Texas,Houston, Houston, TX_

**(904)** Stress Cardiac MRI for Evaluation of Nonspecific Allograft Dysfunction in the Transplanted Heart; __ P. Kim1, F. Contijoch1, D. Wong1, R. Ingle2, A. Hsiao3, J. Santos2, A. Kahn1, M. Pham4, E. McVeigh5, E. Adler1, P. Nguyen6. 1 _Medicine, University of California, San Diego, San Diego, CA,_ 2 _HeartVista, Mountain View, CA,_ 3 _Radiology, University of California, San Diego, San Diego, CA,_ 4 _Medicine, California Pacific Medical Center, San Francisco, CA,_ 5 _Bioengineering, University of California, San Diego, San Diego, CA,_ 6 _Medicine, Stanford University, Palo Alto, CA_

**(905)** Should We Pharmacologically Modulate Renin-Aldosterone-Angiotensin System (RAAS) to Attenuate Cardiac Allograft Vasculopathy? A Prospective Study Using Highly Automated Coronary Optical Coherence Tomography Segmentation Software in 3D; __ M. Pazdernik1, T. Kovarnik1, M. Sonka2, A. Wahle2, Z. Chen2, V. Karmazin2, J. Kautzner1, A. Tomasek3, V. Melenovsky1, H. Bedanova3. 1 _IKEM, Prague, Czech Republic,_ 2 _University of Iowa, Iowa City, IA,_ 3 _Centre of Cardiovascular and Transplantation Surgery, Brno, Czech Republic_

**(906)** Only Persistent Donor Specific Antibodies are Associated with Subsequent Cardiac Allograft Vasculopathy After Heart Transplantation; __ J. A. Kobashigawa, M. Kittleson, T. Aintablian, B. Azarbal, A. Hage, E. Kransdorf, D. Geft, D. Chang, L. Czer, F. Esmailian, X. Zhang, N. Reinsmoen, J. Patel. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(907)** Serial Evaluation of Plaque Characteristics in Coronary Artery Lesions Using Optical Coherence Tomography After Heart Transplantation; __ Y. Tsukamoto1, T. Ohtani1, T. Shiraki1, Y. Ichibori1, S. Saito2, M. Awata1, K. Toda2, O. Yamaguchi1, Y. Sawa2, Y. Sakata1. 1 _Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan,_ 2 _Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Japan_

**(908)** Elevated Body Mass Index Is Associated with Increased Progression of Severe Cardiac Allograft Vasculopathy Despite Revascularization; __ R. Cheng, B. Azarbal, J. Patel, T. Aintablian, D. H. Chang, M. Kittleson, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(909)** Unique Characteristics of Allograft Microvasculature in Patients with Severe Symptomatic Cardiac Allograft Vasculopathy; __ A. Daud, W. D. Xu, P. Revelo, S. Drakos, E. Dranow, A. Kfoury, E. Hammond, J. Nativi-Nicolau, G. Stoddard, R. Alharethi, D. V. Miller, E. M. Gilbert, O. Wever-Pinzon, D. Budge, S. H. McKellar, K. Afshar, J. C. Fang, C. H. Selzman, J. Stehlik. _Utah Transplant Affiliated Hospitals (U.T.A.H.) Cardiac Transplant Program, Salt Lake City, UT_

**(910)** WITHDRAWN

**(911)** Higher Heart Rate Is Associated with Lower Incidence of Coronary Allograft Vasculopathy Requiring Angioplasty; __ A. Selim1, R. Zolty1, A. Burdorf1, A. Siddique2, J. Um2, M. J. Moulton2, B. D. Lowes1, E. Raichlin1. 1 _Cardiology, University of Nebraska Medical Center, Omaha, NE,_ 2 _Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE_

**(912)** Coronary Vasospasm After Heart Transplantation: Does It Portend Poor Outcome?; __ D. Chang, M. Kittleson, J. Patel, T. Aintablian, G. Rodriguez, R. Levine, D. Geft, E. Kransdorf, L. Czer, F. Esmailian, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(913)** Angiogenesis on Coronary Angiography Is a Marker for Accelerated Cardiac Allograft Vasculopathy as Assessed by Intravascular Ultrasound; __ R. Cheng, B. Azarbal, D. Chang, T. Aintablian, L. Czer, J. Patel, J. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(914)** Reduced Coronary Flow Reserve by PET Predicts Cardiovascular Events Following Cardiac Transplantation; __ M. C. Konerman1, J. J. Lazarus1, R. L. Weinberg1, M. Ghannam1, A. Saleh1, H. Yun1, V. M. Moles1, S. L. Hummel1, R. V. Shah2, J. R. Corbett1, K. D. Aaronson1, M. M. Colvin1, T. M. Koelling1, V. L. Murthy1. 1 _University of Michigan, Ann Arbor, MI,_ 2 _Beth Israel Deaconess Medical Center, Boston, MA_

**(915)** Use of Gene Expression Profiling Score Variability to Predict Cardiac Allograft Vasculopathy: A Single Center Experience; __ L. Rejjal1, O. Aldibasi2, S. Sidhu1, S. Ware1, K. Canales1, R. Vasquez1, D. Dumas-Hicks1, S. Desai1, H. Ventura1, S. Krim1. 1 _Ochsner Clinic Foundation, New Orleans, LA,_ 2 _Louisiana State Univ Health Sciences Center, New Orleans, LA_

**(916)** Cocaine Use Does Not Contribute to Accelerated CAD as Determined by Angiography or IVUS; __ S. Beauchamp1, A. Borkon2, K. Karl1, S. Aggarwal1, A. Kao1, A. Magalski3, K. Allen1, B. Austin3, T. Khumari3, S. Lawhorn3, N. Long1, J. Wang4, R. Davis1, E. Thompson1, A. Pak1. 1 _Cardiovascular Surgery, Mid America Heart Institute of Saint Luke's Hospital, Kansas City, MO,_ 2 _Mid America Heart & Lung/St. Luke's, Kansas City, MO, _3 _Cardiology, Mid America Heart Institute of Saint Luke's Hospital, Kansas City, MO,_ 4 _Biostatistics, Mid America Heart Institute of Saint Luke's Hospital, Kansas City, MO_

**(917)** Cardiopulmonary Stress Test One Year After HTx Predicts the Development of CAV; __ E. Raichlin1, A. Selim1, R. Zolty1, A. Burdorf1, A. Siddique2, M. J. Moulton2, J. Um2, B. D. Lowes1. 1 _Cardiology, University of Nebraska Medical Center, Omaha, NE,_ 2 _Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE_

**(918)** Rubidium 82 Positron Emission Tomography in Cardiac Allograft Vasculopathy; __ S. Chih, A. Chong, F. Erthal, R. A. deKemp, D. So, R. A. Davies, E. Stadnick, L. M. Mielniczuk, R. S. Beanlands. _Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada_

**(919)** Coronary Computed Tomography to Screen for Cardiac Allograft Vasculopathy Post Orthotopic Heart Transplant; __ R. Tanner1, J. Buckley1, D. Murphy2, L. Lawler2, N. Mahon3, J. O'Neill1. 1 _Heart Transplant, Mater Misericordiae University Hospital, Dublin, Ireland,_ 2 _Radiology, Mater Misericordiae University Hospital, Dublin, Ireland,_ 3 _Cardiology, Mater Misericordiae University Hospital, Dublin, Ireland_

**(920)** Time Dependent Covariate Method for Assessing Impact of CAV Severity on Mortality After Cardiac Transplantation; __ F. Foroutan1, A. Alba1, S. Bhagra1, J. Duero Posada1, M. Alhussein1, A. K. McDiarmid1, A. Malik1, G. Guyatt2, H. Ross1. 1 _Cardiology, Toronto General Hospital, Toronto, ON, Canada,_ 2 _Health Research Methodology, McMaster University, Hamilton, ON, Canada_

**(921)** Increased Heart Rate After Heart Transplant Is Not Associated with Early Progression of Cardiac Allograft Vasculopathy (CAV) - A Prospective Study Using Highly Automatic Coronary Optical Coherence Tomography Segmentation Software in 3D; __ M. Pazdernik1, T. Kovarnik1, Z. Chen2, A. Wahle2, V. Karmazin1, V. Melenovsky1, J. Kautzner1, A. Tomasek3, H. Bedanova3, M. Sonka2. 1 _IKEM, Prague, Czech Republic,_ 2 _University if Iowa, Iowa City, IA,_ 3 _Centre of Cardiovascular and Transplantation Surgery, Brno, Czech Republic_

**(922)** Percutaneous Intervention Improves Outcome in Cardiac Allograft Vasculopathy; __ R. Sappa1, D. Zanuttini1, S. Sponga1, D. Piani1, C. Nalli1, V. Tursi1, T. Banelli2, A. Proclemer1, U. Livi1. 1 _Azienda Sanitaria Universitaria Integrata di Udine, Udine, Italy,_ 2 _Scienze Mediche e Biotecnologiche, Università degli Studi di Udine, Udine, Italy_

**(923)** Hypomagnesemia and the Risk of Cardiac Allograft Vasculopathy; __ R. Gorantla, S. S. Khan, M. F. Almahmoud, R. Roark, W. Khalife. _University of Texas Medical Branch, Galveston, TX_

**(924)** First Experience with MeltDose-Tacrolimus (Envarsus) in Heart Transplantation; __ K. Uyanik-Uenal, R. Moayedifar, E. Osorio, A. Aliabadi-Zuckermann, T. Haberl, G. Laufer, A. Zuckermann. _Department of Cardiac Surgery, Medical University of Vienna (AKH), Vienna, Austria_

**(925)** The Effect of Everolimus Initiation and Early Calcineurin Inhibitor Withdrawal on Exercise Capacity in De-Novo Heart Transplant Recipients: Results of the SCHEDULE Trial After 36 Months; __ S. Arora1, E. Gude1, K. Karason2, B. Andersson2, S. Bartfay2, D. Solbu3, G. Dellgren2, A. Andreassen1, L. Gullestad1. 1 _Cardiology, Oslo University Hospital, Rikshospitalet, Oslo, Norway,_ 2 _Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden,_ 3 _Novartis Norge, Oslo, Norway_

**(926)** May Intraoperative Immunosuppressive Therapy Reduce the Rejection Episodes at Cardiac Transplant Recipients?; __ M. B. Rabus1, D. Cekmecelioglu1, P. Ata2, S. Salihi3, E. Selcuk1, M. Balkanay4. 1 _Cardiovascular Surgery, Kartal Kosuyolu Heart Research and Training Hospital, Istanbul, Turkey,_ 2 _Medical Genetics, Marmara University Medical Faculty, Istanbul, Turkey,_ 3 _Cardiovascular Surgery, Okan University Medical Faculty, Istanbul, Turkey,_ 4 _Cardiovascular Surgery, Katip Celebi University Medical Faculty, Izmir, Turkey_

**(927)** Heart Transplantation in Patients with Low or High Titer Pre-Formed DSA Is Safe When Performed with a Specific Desensitization Program; __ G. Coutance1, V. D'Orio1, S. Ouldammar1, P. Rouvier2, S. Saheb3, P. Demondion1, N. Bréchot4, N. Ait Hamou5, G. Lebreton1, J. Taupin6, A. Combes4, J. Amour5, P. Leprince1, S. Varnous1. 1 _Thoracic and Cardiovascular Surgery, Groupe Hospitalier Pitié-Salpêtrière, Paris, France,_ 2 _Pathology, Groupe Hospitalier Pitié-Salpêtrière, Paris, France,_ 3 _Hemobiotherapy, Groupe Hospitalier Pitié-Salpêtrière, Paris, France,_ 4 _Medical Intensive Care Unit, Groupe Hospitalier Pitié-Salpêtrière, Paris, France,_ 5 _Anesthesiology and Reanimation, Groupe Hospitalier Pitié-Salpêtrière, Paris, France,_ 6 _Histocompatibility, Hôpital Saint Louis, Paris, France_

**(928)** Survival with Induction Therapy for Simultaneous Heart-Kidney Transplant Recipients on Tacrolimus/Mycophenolate; __ A. A. Amin1, V. K. Ariyamuthu2, M. A. Urey1, F. G. Araj1, M. H. Drazner1, P. P. Mammen1, B. Tanriover2. 1 _Cardiology, UT Southwestern, Dallas, TX,_ 2 _Nephrology, UT Southwestern, Dallas, TX_

**(929)** Impact of Low-Dose Steroids Protocol on Early Outcomes After Cardiac Transplantation: A Brazilian Experience; __ R. M. Carneiro1, V. S. Monteiro1, F. A. Figueira2, D. L. Ferraz2, C. B. Cunha2, J. D. Carvalho Jr2, J. P. Oliveira2, F. R. Walter2, A. H. Baiao1, G. C. Silva3, C. A. Medeiros3, S. Steremberg4, A. R. Lafayette1, A. Kelner2. 1 _Cardiology, Instituto de Medicina Integral Professor Fernando Figueira, Recife, Brazil,_ 2 _Cardiac Surgery, Instituto de Medicina Integral Professor Fernando Figueira, Recife, Brazil,_ 3 _Faculdade Pernambucana de Saúde, Recife, Brazil,_ 4 _Intensive Care Unit, Instituto de Medicina Integral Professor Fernando Figueira, Recife, Brazil_

**(930)** Outcomes Assessment Based on a Risk-Stratified Simple Score After Orthotopic Heart Transplantation; __ K. Morris1, K. A. Lane2, E. Lushin3, J. Finet4, I. Gradus-Pizlo4, A. Hadi4, M. Caccamo4. 1 _Indiana University School of Medicine, Indianapolis, IN,_ 2 _Department of Biostatistics, Indiana University School of Medicine, Indianapolis, IN,_ 3 _Pharmacy, Indiana University School of Medicine, Indianapolis, IN,_ 4 _Cardiology, Indiana University School of Medicine, Indianapolis, IN_

**(931)** WITHDRAWN

**(932)** Side Effects of Proliferation Signal Inhibitors Limit Their Practical Use After Heart Transplantation; __ D. H. Chang, M. Kittleson, J. Patel, T. Aintablian, L. Arakawa, G. Jamero, D. Geft, E. Kransdorf, L. Czer, D. Ramzy, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(933)** Calcineurin Inhibitor Free Immunosuppression in Heart Transplant Recipients Is Associated with Preserved Renal Function and Good Survival: Long Term Follow-Up; __ C. Barbero, S. Fitzsimons, C. Lewis, J. Parameshwar, S. J. Pettit. _Transplant Unit, Papworth Hospital NHS Foundation Trust, Cambridge, United Kingdom_

**(934)** The Effect of Donor Arginine Vasopressin Use within 24 Hours of Aortic Cross-Clamp on 1-Year Recipient Survival; __ S. K. Lella1, K. Zolfaghari2, L. A. Copeland2, C. B. Sai-Sudhakar3, Y. Ravi3. 1 _College of Medicine, Texas A &M University, Dallas, TX, _2 _Center for Applied Health Research, Baylor Scott and White Health, Temple, TX,_ 3 _Cardiothoracic Surgery-Surgery, Baylor Scott & White Healthcare, Temple, TX_

**(935)** Absolute Lymphocyte Count Before Induction Therapy with Basiliximab Can Predict Fatal Infection in Heart Transplant Recipients; __ J. Oh, I. Kim, S. Lee, H. Park, Y. Youn, S. Kang. _Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of_

**(936)** Extended Use of rATG or Basiliximab Allows Delayed CNI Initiation in Patients with Renal Dysfunction After Heart Transplantation; __ V. Manfredini, S. Pettit, C. Lewis, D. Brahmbatt, J. Parameshwar, A. Kydd. _Papworth Hospital, Cambridge, United Kingdom_

**(937)** Is Tacrolimus/Proliferation Signal Inhibitor (PSI) Comparable to Cyclosporine/PSI After Heart Transplantation?; __ D. Chang, M. Kittleson, J. Patel, T. Aintablian, A. Velleca, G. Jamero, E. Kransdorf, D. Geft, L. Czer, F. Esmailian, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(938)** Despite FDA Black Box Warning, Proliferation Signal Inhibitor (PSI) in the First Year with Induction Therapy Appears Safe in Heart Transplant Patients; __ J. Patel, M. Kittleson, T. Aintablian, G. Esmailian, A. Velleca, A. Hage, E. Kransdorf, D. Geft, D. H. Chang, L. Czer, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(939)** Increased Risk of Rejection and Mortality in Heart Transplant Patients Receiving Granulocyte-Colony Stimulating Factor; __ A. Nguyen, L. Lourenco, N. Bassi, T. Imamura, N. Sarswat, J. Raikhelkar, S. Adatya, G. Kim, C. Murks, J. Powers, T. Riley, V. Jeevanandam, G. Sayer, N. Uriel. _University of Chicago, Chicago, IL_

**(940)** The Use of Intra-Aortic Balloon Pump Pre-Transplant Is Associated with Worse Outcomes in Heart Transplant Recipients; __ D. Vucicevic1, L. Honoris1, A. Chang1, E. Moreno1, A. Salimbangon1, M. Moore1, L. Sweet1, S. Shah1, A. Iyengar1, K. Pandya2, A. Ardehali3, M. Deng1, E. DePasquale1. 1 _Department of Cardiology, UCLA, Los Angeles, CA,_ 2 _Department of Cardiology, UC Davis, Davis, CA,_ 3 _Department of Cardiothoracic Surgery, UCLA, Los Angeles, CA_

**(941)** Severe Obesity in Heart Transplant Correlates with Increased Primary Graft Dysfunction but Not with One-Year Mortality; __ M. J. Sherwood, S. M. Joseph, G. Saracino, S. A. Carey, J. Felius, T. Chamogeorgakis, A. E. Rafael, J. C. MacHannaford, G. V. Gonzalez-Stawinski, S. A. Hall, B. Lima. _Baylor University Medical Center, Dallas, TX_

**(942)** Mid- to Long-Term Experience of Multiple Organ Heart Transplantation in a Mid-Size Center in Germ; __ T. Sandhaus1, M. Leuze1, M. Dordevic1, G. Faerber1, H. Kirov1, M. Breuer2, M. Grimm3, U. Settmacher4, T. Doenst1. 1 _Department of Cardiothoracic Surgery, Friedrich Schiller University, Jena, Germany,_ 2 _Department of Cardiac Surgery, Central Clinic, Bad Berka, Germany,_ 3 _Department of Urology, Friedrich Schiller University, Jena, Germany,_ 4 _Department of General, Abdominal and Vascular Surgery, Friedrich Schiller University, Jena, Germany_

**(943)** The Impact of Socioeconomic Factors on Heart Transplant Outcomes; __ A. L. Clark1, R. Watkins2, J. Katz3, B. Jensen3, L. Rose-Jones3, S. Waters3, M. Andrews3, P. Chang3. 1 _Internal Medicine, University of North Carolina, Chapel Hill, NC,_ 2 _University of North Carolina, Chapel Hill, NC,_ 3 _Cardiology, University of North Carolina, Chapel Hill, NC_

**(944)** Contemporary Analysis of Heart Transplantation Outcomes in Patients with Neuromuscular Cardiomyopathies; __ F. Kamdar1, R. Urban2, L. B. Edwards3, P. P. Mammen4, J. Stehlik5, D. O. Taylor6. 1 _Cleveland Clinic, University of Minnesota, Minneapolis, MN,_ 2 _United Network for Organ Sharing, Richmond, VA,_ 3 _United Network for Organ Sharing, International Society of Heart and Lung Transplantation Registry, Richmond, VA,_ 4 _University of Texas Southwestern, Dallas, TX,_ 5 _International Society of Heart and Lung Transplantation Registry, University of Utah, Salt Lake City, UT,_ 6 _Cleveland Clinic, Cleveland, OH_

**(945)** High Urgency Heart Transplantation in Vienna, Austria; __ E. N. Osorio-Jaramillo1, A. Z. Aliabadi-Zuckermann1, R. Moayedifar1, K. L. Freystaetter2, T. Haberl1, K. Uyanik-Uenal1, G. Laufer1, A. O. Zuckermann1. 1 _Division of Cardiac Surgery, Medical University of Vienna, Vienna, Austria,_ 2 _Cardiovascular Surgery, Bern University Hospital, Bern, Switzerland_

**(946)** Heart Failure After Heart Transplantation. Incidence, Etiology and Outcomes; __ Á. López-Sainz, E. Barge-Caballero, G. Barge-Caballero, D. Couto-Mallón, M. Paniagua-Martin, L. Seoane-Quiroga, C. Iglesias-Gil, J. Herrera-Noreña, J. Cuenca-Castillo, J. Vázquez-Rodriguez, M. Crespo-Leiro. _Cardiology, Complejo Hospitalario Universitario A Coruña, A Coruña, Spain_

## Lung Transplantation

(Harbor Foyer)

**Poster Discussants:** Hakim A Ali, MD (USA), Cecilia Chaparro, MD (Canada), Christopher Ensor, PharmD, BCPS-CV (USA), Steven C Juvet, MD, PhD, FRCPC (Canada), Tanya J McWilliams, MD, PhD (New Zealand), Antoine Roux, MD, PhD (France), Helen M Whitford, MBBS, FRACP (Australia), Keith M Wille, MD, MSPH (USA), Bryan A Whitson, MD (USA)

**(947)** WITHDRAWN

**(948)** WITHDRAWN

**(949)** Pirfenidone as a Bridge Therapy for Lung Transplantation; __ S. Tanaka, K. Miyoshi, T. Kurosaki, S. Otani, S. Sugimoto, M. Yamane, T. Oto. _Department of Thoracic Surgery, Organ Transplant Center, Okayama University Hospital, Okayama, Japan_

**(950)** Post Lung Transplant Survival of Recipients with Sarcoidosis in LAS Era; __ J. Mooney1, J. Boyd2, L. Chhatwani1, G. S. Dhillon1. 1 _Medicine, Stanford University School of Medicine, Stanford, CA,_ 2 _Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA_

**(951)** Extracorporeal Membrane Oxygenation Bridge to Lung Transplantation: A Single Center Report; __ N. S. Sharma, V. G. Valentine, V. Rusanov, R. A. Schwartz, S. C. Bellot, B. Wei, C. R. Baker, E. Diaz-Guzman, C. W. Hoopes, K. M. Wille. _Univ of Alabama at Birmingham, Birmingham, AL_

**(952)** Pre-Transplant Delayed Gastric Emptying Does Not Correlate with Incidence of Acute Rejection or Bronchiolitis Obliterans Syndrome After Lung Transplantation; __ A. Kafi1, J. Falk1, G. Chaux1, S. Ghandehari1, W. Cheng2, D. Ramzy2. 1 _Pulmonary and Critical Care, Cedars Sinai Medical Center, Los Angeles, CA,_ 2 _Cardiothoracic Surgery, Cedars Sinai Medical Center, Los Angeles, CA_

**(953)** Association of Methacholine Challenge Test with Diagnosis of Bronchiolitis Obliterans Syndrome in Lung Transplant Patients; __ A. Siddiqui1, F. Zahiruddin1, G. Kumar2, A. Goodarzi3, J. Youssef3, T. Majumdar1, N. Sinha3, T. Kaleekal3. 1 _Pulmonary and Critical Care, Houston Methodist Hospital, Houston, TX,_ 2 _Pulmonary and Critical Care, Northeast Georgia Medical Center, Gainesville, FL,_ 3 _Pulmonary Transplant, Houston Methodist Hospital, Houston, TX_

**(954)** Normal Impact of Restrictive and Obstructive Subtypes of Chronic Lung Allograft Dysfunction on Graft Survival - Single Center 13 Year Experience; __ A. I. Nykänen1, M. Halme2, C. Stark3, P. Hämmäinen3, K. B. Lemström1, P. Raivio3. 1 _Cardiac Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland,_ 2 _Pulmonary Diseases, Helsinki University Hospital, Helsinki, Finland,_ 3 _Cardiac Surgery, Helsinki University Hospital, Helsinki, Finland_

**(955)** Automating the Diagnosis of Potential CLAD and Its Subtypes in Lung Transplant Recipients; __ W. Klement1, J. Tikkanen2, S. Juvet2, J. L. Todd3, S. S. Weigt4, L. D. Snyder3, S. Azad5, J. A. Belperio4, S. M. Palmer3, L. G. Singer2, S. Keshavjee6, T. Martinu7. 1 _Latner Thoracic Surgery Laboratories, University Health Network / University of Toronto, Toronto, ON, Canada,_ 2 _Toronto Lung Transplant Program, University Health Network / University of Toronto, Toronto, ON, Canada,_ 3 _Division of Pulmonary, Allergy, and Critical Care Medicine, Duke University, Durham, NC,_ 4 _Dept. of Medicine, Ronald Reagan UCLA Medical Center, Los Angeles, CA,_ 5 _Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada,_ 6 _Toronto Lung Transplant Program, Latner Thoracic Surgery Laboratories, University Health Network / University of Toronto, Toronto, ON, Canada,_ 7 _Division of Respirology & Lung Transplant Program, University Health Network / University of Toronto, Toronto, ON, Canada_

**(956)** Lung Retransplantation for CLAD- Does the Phenotype of CLAD Affect the Survival? A Retrospective Explorative Study; __ M. M. Schuster, G. Muraközy, C. Lambers, A. Benazzo, S. Schwarz, W. Klepetko, P. Jaksch. _Division of Thoracic Surgery, Medical University of Vienna, Vienna, Austria_

**(957)** Early Natural Killer Frequencies and Chronic Lung Allograft Dysfunction Two Years After Lung Transplantation; __ J. Salman, F. Ius, T. Siemeni, M. Avsar, W. Sommer, A. Knöfel, C. Kuehn, C. Falk, T. Welte, J. Gottlieb, A. Haverich, I. Tudorache, G. Warnecke. _Hannover Medical School, Hannover, Germany_

**(958)** Increased Interstitial Neutrophils in Lung Transplant Recipients with Donor Specific Antibodies as a Potential Marker of Subclinical AMR-Related Events; __ L. Godinas1, J. Lepavec2, V. de Montpreville2, M. Ghigna2, S. Mussot2, O. Mercier2, E. Fadel2, P. Dorfmüller2. 1 _CHU UCL Namur, Yvoir, Belgium,_ 2 _Centre Chirurgical Marie Lannelongue, Le Plessis-Robinson, France_

**(959)** Bronchiolitis-Obliterans Syndrome-Free Survival of Lung Transplant Recipients - Analysis of the ISHLT Registry; __ H. S. Kulkarni, R. R. Hachem, E. P. Trulock, D. E. Byers, C. A. Witt, R. D. Yusen. _Medicine, Division of Pulmonary and Critical Care Medicine, Washington University in Saint Louis, Saint Louis, MO_

**(960)** Clinical Characteristics & Outcomes of Restrictive CLAD After Bilateral Living-Donor Lobar Lung Transplantation; __ K. Mesaki, K. Miyoshi, S. Namura, T. Kurosaki, S. Otani, S. Sugimoto, M. Yamane, S. Miyoshi, T. Oto. _Department of Thoracic Surgery, Organ Transplant Center, Okayama University Hospital, Okayama, Japan_

**(961)** In Vitro Analysis of RBC-Mediated Lung Injury in Prolonged Ex Vivo Lung Perfusion; __ J. R. Spratt1, G. Loor1, L. M. Mattison2, C. Meyer3, M. Ehrhardt3, H. Helms3, A. Panoskaltsis-Mortari3. 1 _Department of Surgery, University of Minnesota, Minneapolis, MN,_ 2 _Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN,_ 3 _Department of Pediatrics, University of Minnesota, Minneapolis, MN_

**(962)** Cytokine Levels in Steen Solution Perfusate Increase During Ex-Vivo Lung Perfusion (EVLP) of Lungs from Conventional Donors (Conv) and Uncontrolled Donation After Circulatory Determination of Death Donors (uDCDDs); __ S. Masuodi1, J. Blackwell1, P. Stewart2, T. M. Egan1. 1 _Surgery, U. North Carolina Sch Med, Chapel Hill, NC,_ 2 _Biostatistics, Gillings Global School of Public Health, UNC, Chapel Hill, NC_

**(963)** Lung Transplantation from DCD Donors After Prolonged Normothermic Portable EVLP; __ J. R. Spratt1, L. M. Mattison2, P. A. Iaizzo1, C. Meyer3, T. L. Iles1, A. Panoskaltsis-Mortari3, G. Loor1. 1 _Department of Surgery, University of Minnesota, Minneapolis, MN,_ 2 _Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN,_ 3 _Department of Pediatrics, University of Minnesota, Minneapolis, MN_

**(964)** EVLP: A Monocentric Five Year Experience; __ V. Rossetti1, L. Morlacchi1, P. Tarsia1, G. Ruggeri2, L. Rosso3, M. Nosotti3, F. Blasi1, D. Tosi3, F. Valenza4. 1 _Department of Pathophysiology and Transplantation, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico di Milano; Università degli Studi di Milano, Milano, Italy,_ 2 _Dipartimento di Anestesia Rianimazione (Intensiva e Subintensiva) e Terapia del dolore, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico di Milano; Università degli Studi di Milano, Milano, Italy,_ 3 _U.O. Chirurgia Toracica e dei Trapianti di Polmone, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico di Milano; Università degli Studi di Milano, Milano, Italy,_ 4 _Dipartimento di Anestesia, Rianimazione (Intensiva e Subintensiva) e Terapia del Dolore, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico di Milano; Università degli Studi di Milano, Milano, Italy_

**(965)** How to Resolve Large Atelectasis in Ex Vivo Lung Perfusion?; __ T. Okamoto1, H. Niikawa2, D. Wheeler3, B. Soliman1, K. Ayyat2, G. Sunagawa4, K. R. McCurry5. 1 _Transplant Center, Cleveland Clinic, Cleveland, OH,_ 2 _Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH,_ 3 _Pediatric Respiratory Therapy, Medical University of South Carolina, Charleston, SC,_ 4 _Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH,_ 5 _Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH_

**(966)** Post-Lung Transplant Outcome & Risk Matching Between Donor & Recipient - Score-Based Analyses; __ K. Miyoshi, T. Kurosaki, S. Otani, S. Sugimoto, M. Yamane, T. Oto. _Department of Thoracic Surgery / Organ Transplant Centre, Okayama University Hospital, Okayama, Japan_

**(967)** Lung Transplant from Donors After Previous Cardiac Surgery: Ideal Graft in Marginal Donor?; __ A. Palleschi1, D. Tosi1, P. Mendogni1, M. Montoli1, P. Tarsia2, V. Rossetti2, F. Valenza3, M. Nosotti1, L. Santambrogio1. 1 _Thoracic Surgery and Lung Transplant Unit, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy,_ 2 _Pneumology Unit, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy,_ 3 _Anesthesia and Intensive Care Unit, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy_

**(968)** Does Post-Lung Transplant Mortality Vary by Diagnosis For a Given Lung Allocation Score?; __ H. Maredia1, M. Bowring1, A. Massie1, S. Oyetunji1, C. Merlo2, R. Higgins1, D. Segev1, E. Bush1. 1 _Department of Surgery, Johns Hopkins University, Baltimore, MD,_ 2 _Department of Medicine, Johns Hopkins University, Baltimore, MD_

**(969)** Effect of Favorable Donor Factors on Outcomes After Bilateral Lung Transplantation: Preliminary Prospective Analysis of the University of Minnesota Donor Lung Quality Index (UMN-DLQI); __ G. Loor1, S. Huddleston1, S. Jackson2, S. Elde3, T. Grabowski2, R. Kelly1, S. Shumway1, M. Hertz3. 1 _Surgery, University of Minnesota, Minneapolis, MN,_ 2 _Fairview Medical Center, Minneapolis, MN,_ 3 _University of Minnesota, Minneapolis, MN_

**(970)** 5-Year Mortality Is Superior in COPD Patients That Receive Double vs Single Lung Transplants; __ T. C. Crawford1, A. Suarez-Pierre1, J. Magruder1, J. C. Grimm1, J. Ha1, R. Stephens2, B. S. Kim2, C. A. Merlo2, S. Broderick3, E. L. Bush3. 1 _General Surgery, Johns Hopkins University, Baltimore, MD,_ 2 _Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD,_ 3 _General Surgery, Division of Thoracic Surgery, Johns Hopkins University, Baltimore, MD_

**(971)** ABO-Identical Matching Has No Superiority in Survival in Comparison to ABO-Compatible Matching in Lung Transplantation; __ M. Fakhro1, R. Ingemansson1, L. Algotsson2, S. Lindstedt1. 1 _Dept. of Cardiothoracic Surgery, Skåne University Hospital, Lund University, Lund, Sweden,_ 2 _Dept. of Thoracic Intensive Care and Anesthesia, Skåne University Hospital, Lund University, Lund, Sweden_

**(973)** The Effect of Oversizing Donor Lungs for Recipients with Pulmonary Fibrosis Undergoing Single or Bilateral Lung Transplantation; __ H. Doshi, E. Pavlushkov, B. Marius, P. Catarino, J. David, J. Parmar. _Papworth Hospital, Papworth Everard, United Kingdom_

**(974)** Influence of Ischemic Time on Post Lung Transplant (LT) Outcomes; __ A. Iyengar1, E. Adams1, N. Harati1, C. Eisenring2, D. Ross3, E. DePasquale4, A. Ardehali2. 1 _David Geffen School of Medicine, University of California - Los Angeles, Los Angeles, CA,_ 2 _Department of Cardiac Surgery, University of California - Los Angeles, Los Angeles, CA,_ 3 _Department of Pulmonology, University of California - Los Angeles, Los Angeles, CA,_ 4 _Department of Cardiology, University of California - Los Angeles, Los Angeles, CA_

**(975)** Lung Donation After Drowning; __ J. Salman, F. Ius, T. Siemeni, W. Sommer, M. avsar, C. Kuehn, T. Welte, J. Gottlieb, A. Haverich, G. Warnecke, I. Tudorache. _Hannover Medical School, Hannover, Germany_

**(976)** Impact of Diabetes Mellitus and Glycemic Control in Lung Transplant Donors on Recipient Survival; __ V. R. Esposito1, M. S. Mulvihill2, M. G. Hartwig3. 1 _Duke University School of Medicine, Durham, NC,_ 2 _Duke Surgery, Duke Health, Durham, NC,_ 3 _Duke Cardiovascular and Thoracic Surgery, Duke Health, Durham, NC_

**(977)** Impaired Preoperative Renal Function Should Not Be a Barrier to Transplantation in Patients with Cystic Fibrosis; __ T. C. Crawford1, J. Magruder1, J. C. Grimm1, A. Suarez-Pierre1, X. Zhou1, J. S. Ha2, S. R. Broderick1, C. A. Merlo3, B. S. Kim3, E. L. Bush1. 1 _General Surgery, Johns Hopkins University, Baltimore, MD,_ 2 _Cardiothoracic Surgery, Johns Hopkins University, Baltimore, MD,_ 3 _Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD_

**(978)** Smoking Donors in Lung Transplantation: Clinical and Pathological Study of Their Impact at Short- and Long-Term Outcomes; __ M. Schiavon1, G. Marulli1, M. Loy1, F. Lunardi1, G. Di Gregorio2, A. Lloret1, F. Calabrese1, F. Rea1. 1 _Cardiac, Thoracic and Vascular Sciences, University of Padua, Padova, Italy,_ 2 _Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy_

**(979)** Suicidal Hanging Donors for Lung Transplantation: Is This Chapter Still Closed? Midterm Experience from a Single Centre; __ O. Ananiadou1, B. Zych1, D. Garcia Saez1, P. Mohite1, B. Schmack1, L. Fazekas1, M. Husain1, A. Jothidasan1, A. Sabashnikov1, A. Weymann1, A. Reed2, M. Carby2, F. De Robertis1, A. R. Simon1, A. Popov1. 1 _Cardiothoracic Transplantation and Mechanical Circulatory Support, Harefield Hospital, Harefield, United Kingdom,_ 2 _Transplant and Respiratory Medicine, Harefield Hospital, Harefield, United Kingdom_

**(980)** Native-Upper Lobe-Sparing Living Donor Lobar Lung Transplantation Enables to Maximize Donor Graft Respiratory Fluctuation; __ A. Takahagi, T. F. Chen-Yoshikawa, K. Ohata, M. Saito, R. Okabe, F. Gochi, H. Yamagishi, M. Hamaji, H. Motoyama, K. Hijiya, A. Aoyama, H. Date. _Thoracic Surgery, Kyoto University Gradual School, Kyoto, Japan_

**(981)** Lung Transplant Outcomes in Donors Managed with Airway Pressure Release Ventilation; __ S. Biswas Roy1, C. Haworth2, M. Olson3, P. Kang4, K. E. Varsch1, T. S. Panchabhai1, R. M. Bremner1, M. A. Smith1, R. Walia1. 1 _Norton Thoracic Institute, St. Joseph's Hospital & Medical Center, Phoenix, AZ, _2 _A.T. Still University, Mesa, AZ,_ 3 _Grand Canyon University, Phoenix, AZ,_ 4 _University of Arizona College of Public Health, Phoenix, AZ_

**(982)** Lung Transplantation with Controlled Donation After Circulatory Death Donors: Initial Experience in Switzerland; __ I. Inci, R. Lenherr, S. Hillinger, D. Schneiter, M. Beschir, I. Schmitt-Opitz, R. Schuepbach, M. Schuurmans, C. Benden, W. Weder. _University Hospital, Zurich, Switzerland_

**(983)** Impact of Prolonging CMV Prophylaxis in High Risk (CMV D+/R-) Lung Transplant Recipients; __ B. Khan1, S. Husain1, M. Binnie1, C. Chow1, T. Martinu1, C. Chaparro1, S. Keshavjee2, L. G. Singer1, J. Tikkanen1. 1 _Toronto General Hospital, Toronto, ON, Canada,_ 2 _Department of Thoracic Surgery, Toronto General Hospital, Toronto, ON, Canada_

**(984)** CMV: Reactivation and Prematurely Discontinued Prophylaxis; __ D. Briganti1, G. Lunghi2, A. D'adda1, L. Morlacchi1, A. Palleschi3, P. Mendogni3, I. Righi3, F. Blasi1. 1 _Department of Pathophysiology and Transplantation, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico di Milano; Universita ̀ degli Studi di Milano, Milano, Milano, Italy, _2 _U.O.S. Virologia, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico di Milano; Universita ̀ degli Studi di Milano, Milano, Milano, Italy, _3 _U.O. Chirurgia Toracica e dei Trapianti di Polmone, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico di Milano; Universita ̀ degli Studi di Milano, Milano, Milano, Italy_

**(985)** Posaconazole Extended-Release Tablets for Pre-Emptive Anti-Fungal Therapy Post Lung Transplantation; __ S. P. Ivulich1, D. Seymour1, L. Hunt1, G. Snell2. 1 _Pharmacy, Alfred Hospital, Melbourne, Australia,_ 2 _Lung Transplant Service, Alfred Hospital, Melbourne, Australia_

**(986)** The Unnatural History of Early Lower Respiratory Tract Infection After Lung Transplantation ; __ A. B. Mitchell1, G. Calligaro2, M. A. Malouf2, M. Benzimra2, A. Rigby2, R. Pearson2, A. Havryk2, M. Plit2, A. R. Glanville2. 1 _Molecular Biology, University of Technology, Sydney, Australia,_ 2 _Lung Transplant Unit, St Vincent's Hospital, Sydney, Australia_

**(987)** Clinical Assessment of Cytomegalovirus Specific Cell Mediated Immunity in a Prospective Cohort of Lung Transplant Recipients; __ S. V. Campos1, M. N. Samano2, P. M. Pego-Fernandes2, R. O. Teixeira1, R. M. Carraro1, J. E. Afonso-Junior1, A. N. Costa1, C. M. Machado3, A. C. Souza4, B. B. Pereira5, L. M. Fernandes2, L. Abdalla2. 1 _Pneumology, Heart Institute of Sao Paulo Medical School, Sao Paulo, Brazil,_ 2 _Thoracic Surgery, Heart Institute of Sao Paulo Medical School, Sao Paulo, Brazil,_ 3 _Virology Laboratory (LIM 52-HCFMUSP), Institute of Tropical Medicine of Sao Paulo Medical School, Sao Paulo, Brazil,_ 4 _Virology Laboratory (LIM 52 HCFMUSP), Institute of Tropical Medicine of Sao Paulo Medical School, Sao Paulo, Brazil,_ 5 _Virology Laboratory (LIM 52-HCFMUSP), Institute of Tropical Medicine of Sao Paulo Medical Schoolof Sao Paulo Medical School, Sao Paulo, Brazil_

**(988)** A Prophylaxis-Free, Pre-Emptive Approach to the Management of CMV After Lung Transplantation: Single Center Results; __ A. Bertani1, P. Vitulo2, A. Mularoni3, P. Grossi3, L. De Monte1, E. Russo1, M. Beretta2, L. Martino2, A. Callari2. 1 _Thoracic Surgery and Lung Transplantation, IRCCS ISMETT- UPMC Italy, Palermo, Italy,_ 2 _Pulmonology, IRCCS ISMETT- UPMC Italy, Palermo, Italy,_ 3 _Infectious Diseases, IRCCS ISMETT- UPMC Italy, Palermo, Italy_

**(989)** Donors with Bacterial Meningitis: Outcomes in Lung Transplant Recipients; __ H. Grewal1, M. Budev2. 1 _Cleveland Clinic Foundation, Parma, OH,_ 2 _Cleveland Clinic Foundation, Cleveland, OH_

**(990)** Acute Rejection Interaction with Viral Pneumonia Augments CLAD Risk; __ A. L. Gregson, J. Grotts, M. Shino, S. S. Weigt, J. Belperio. _UCLA, Los Angeles, CA_

**(991)** Management of Pseudomonas aeruginosa Infection After Lung Transplantation Across the UK and the Impact on Long-Term Survival; __ T. C. Gan1, A. E. Cockburn2, H. Yung3, E. Karimi4, L. Dirmantaite5, M. Khan6, A. Perry2, R. Gell5, M. Al-Aloul4, R. D. Thompson7, J. Parmar3, M. Carby5, A. J. Fisher2, O. Association of Lung Transplant Physicians UK2. 1 _Pulmonary Diseases, Tuberculosis and Lung Transplantation, University Medical Center Groningen, Groningen, Netherlands,_ 2 _Cardiopulmonary Transplantation Unit, Freeman Hospital, Newcastle, United Kingdom,_ 3 _Lung Transplantation Unit, Papworth Hospital, Cambridge, United Kingdom,_ 4 _Lung Transplantation Unit, University Hospital South Manchester, Manchester, United Kingdom,_ 5 _Lung Transplantation Unit, Royal Brompton and Harefield, Middlesex, United Kingdom,_ 6 _Respiratory Medicine, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom,_ 7 _Lung Transplantation Unit, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom_

## Mechanical Circulatory Support

(Seaport Foyer)

**Poster Discussants:** Dipanjan Banerjee, MD (USA), Markus J Barten, MD, PhD (Germany), Alexander M Bernhardt, MD (Germany), Edo Y Birati, MD (USA), Pamela Combs, PhD, RN (USA), Jennifer A Cowger, MD, MS (USA), Sung-Ho Jung, MD (Korea), Liviu Klein, MD (USA), Brent C Lampert, DO (USA), Antonio Loforte, MD (Italy), Simon Maltais, MD, PhD (USA), Nahush A Mokadam, MD (USA), Chetan B Patel, MD (USA), Sarah Schettle, PA-C (USA), Garrick C Stewart, MD (USA), Andre Vincentelli, MD, PhD (France), Andrae Wasler, MD (Austria), Daniel Zimpfer, MD (Austria)

**(992)** Biologically-Inspired Spiral Flow Generation for Mechanically Assisted Circulation; __ C. D. Tkatch1, P. S. Huang Zhang1, W. Fischer1, H. Eisen2, J. Yasha Kresh1. 1 _Cardiothoracic Surgery, Drexel University College of Medicine, Philadelphia, PA,_ 2 _Department of Medicine, Drexel University College of Medicine, Philadelphia, PA_

**(993)** Percutaneous Right Ventricular Assist Device Outcomes: Protek Duo; __ A. Ravichandran1, D. A. Baran2, J. A. Cowger1, C. T. Salerno3, K. Stelling2, S. Kapoor2, T. Martin2, J. Pieretti2, C. Gidea2, M. J. Zucker2, B. Dinicola4, M. Camacho2. 1 _St Vincents Heart Center, Indianapolis, IN,_ 2 _Transplant Center, Newark Beth Israel Medical Ctr, Livingston, NJ,_ 3 _Cardiac Surgery, St Vincents Heart Center, Indianapolis, IN,_ 4 _Heart Transplant, St Vincents Heart Center, Indianapolis, IN_

**(994)** Outcomes of Tandem Percutanous LVAD Support; __ D. A. Baran, K. Stelling, J. Pieretti, C. Gidea, S. Kapoor, M. Zucker, T. Martin, B. Dinicola, M. Camacho. _Newark Beth Israel Medical Ctr, Newark, NJ_

**(995)** Comparisons in Clotting Parameters Between Species for Preclinical Animal Studies; __ T. Mizuno, T. Tsukiya, Y. Takewa, E. Tatsumi. _Dept. of Artificial Organs, Nat'l Cerebral CV Ctr, Suita, Japan_

**(997)** Experimental and Numerical Analysis of Dye Washout in Ventricular Assist Devices; __ A. Molteni1, H. Yousef2, K. Low2, H. Porter3, K. Fraser3. 1 _Calon Cardio - Technology, Swansea, United Kingdom,_ 2 _ASTUTE 2020, Swansea University, Swansea, United Kingdom,_ 3 _Mechanical Engineering, University of Bath, Bath, United Kingdom_

**(998)** Testing 3D Pulsatile Prototypes of Left Ventricular Assist Device; __ I. G. Berra1, M. L. Berra2, M. A. Lewis3, H. Vogelfang1, G. Naiman1, S. Berra4. 1 _Heart Transplant Department, Hospital Garrahan Argentina, Buenos Aires, Argentina,_ 2 _Clinica Department, Hospital Posadas Argentina, Buenos Aires, Argentina,_ 3 _Medical Research, Lew Supplies and Innovations, Buenos Aires, Argentina,_ 4 _Control Department - Facultad de Ingenieria, Universidad de Buenos Aires, Buenos Aires, Argentina_

**(999)** Development of a Novel Tip Less Inflow Conduit for Left Ventricular Assist Device; __ K. Iizuka1, K. Yamazaki2, T. Motomura3, T. Nishinaka2, Y. Takewa1, T. Mizuno1, T. Tsukiya1, N. Naito1, D. Akiyama1, E. Tatsumi1. 1 _Department of Artificial Organs, National Cerebral and Cardiovascular Center, Osaka, Japan,_ 2 _Department of Cardiovascular Surgery, Tokyo Women's Medical University, Tokyo, Japan,_ 3 _Evaheart, Inc., Houston, TX_

**(1000)** Utility of Computation Fluid Dynamics in Assessing Relationship of Aortic Regurgitation with Outflow Graft Orientation in Patients with Left Ventricular Assist Devices; __ M. Kassi, J. A. Guerra, A. Bhimaraj, S. Chang, C. Karmonik, J. Estep. _Cardiology, Houston Methodist Hospital, Houston, TX_

**(1001)** Reliability of a Cuff-Deflation System for Serial Monitoring of Aortic Pulse Wave Velocity in Patients with Continuous-Flow Left Ventricular Assist Devices; __ F. Castagna1, A. Pinsino1, E. J. Stöhr1, B. McDonnell2, M. Yuzefpolskaya1, A. Clemons1, N. Akter1, D. Onat1, D. L. Brunjes1, K. Ross1, M. Tiburcio1, V. K. Topkara1, A. R. Garan1, H. Takayama1, K. Takeda1, Y. Naka1, J. Cockcroft2, P. C. Colombo1. 1 _New York Presbyterian Hospital - Columbia University Medical Center, New York, NY,_ 2 _Cardiff Metropolitan University, Cardiff, United Kingdom_

**(1002)** Predictors of Ventricular Recovery After Acute Myocardial Infarction Complicated by Cardiogenic Shock; __ C. Eckhardt, K. Takeda, H. Takayama, V. K. Topkara, A. Masoumi, J. Fried, K. Clerkin, M. Yuzefpolskaya, R. Te-Frey, A. Kirtane, D. Karmpaliotis, Y. Naka, P. C. Colombo, A. R. Garan. _Columbia University, New York, NY_

**(1003)** Older Age Combined with Reduced Renal Function Has a Strong Cumulative Adverse Effect on Survival in Left Ventricular Assist Device Patients; __ R. Muslem1, K. Caliskan1, S. Akin1, E. Y. Yasar1, A. J. Bogers2, D. Hesselink3, G. J. Whitman4, R. J. Tedford5, O. C. Manintveld1, S. D. Russell5. 1 _Cardiology, Erasmus MC, Rotterdam, Netherlands,_ 2 _Cardiothoracic Surgery, Erasmus MC, Rotterdam, Netherlands,_ 3 _Nephrology, Erasmus MC, Rotterdam, Netherlands,_ 4 _Cardiothoracic Surgery, Johns Hopkins School of Medicine, Baltimore, MD,_ 5 _Cardiology, Johns Hopkins School of Medicine, Baltimore, MD_

**(1004)** Cardiac Rotational Mechanics as a Predictor of Favorable Functional Response Induced by Cardiac Assist Devices in Advanced Heart Failure; __ S. G. Drakos1, I. Taleb1, R. Larsen1, O. Wever-Pinzon1, A. G. Kfoury2, R. Alharethi2, J. Nativi-Nicolau1, W. Caine2, S. H. McKellar1, A. Koliopoulou1, C. H. Selzman1, S. G. Drakos1. 1 _University of Utah, Salt Lake City, UT,_ 2 _Intermountain Medical Center, Salt Lake City, UT_

**(1005)** Renal Failure Is Not a Contraindication to Left Ventricular Assist Device Implantation; __ A. Kilic, C. W. Chen, A. C. Gaffey, J. W. Wald, M. A. Acker, P. Atluri. _University of Pennsylvania, Philadelphia, PA_

**(1006)** ECMO-Bridge to LVAD Therapy Is a Safe and Effective Strategy for Critically Ill Patients; __ J. J. Han1, C. Chen1, J. Chung1, A. C. Gaffey1, A. Sotolongo1, C. M. Justice1, J. E. Rame2, C. Bermudez1, M. A. Acker1, P. Atluri1. 1 _Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA,_ 2 _Cardiology, Hospital of the University of Pennsylvania, Philadelphia, PA_

**(1007)** The Impact of a VAD Prior Authorization Program on Patient Outcomes; __ L. L. Ten Eyck1, W. M. Bannister1, E. Liu1, A. Bonagura2, D. Irwin2, M. Chen2. 1 _Optum Consumer Solutions Group Healthcare Analytics, Optum, Minneapolis, MN,_ 2 _Complex Medical Conditions, Optum, Minneapolis, MN_

**(1008)** Decoupling Between Diastolic Pulmonary Artery Pressure and Pulmonary Capillary Wedge Pressure Is the Strongest Negative Prognostic Factor Post Continuous Flow Ventricular Assist Device Implantation; __ T. Imamura1, G. Sayer1, S. Adatya1, N. Sarswat1, G. Kim1, J. Raikhelkar1, T. Ota1, T. Song1, C. Juricek1, V. Kagan1, D. Rodgers1, V. Jeevanandam1, D. Burkhoff2, M. Mehra3, N. Uriel1. 1 _University of Chicago, Chicago, IL,_ 2 _University of Columbia, New York, NY,_ 3 _Brigham and Women's Hospital, Boston, MA_

**(1009)** Adult ECMO for Acute Cardiorespiratory Failure: Should There Be a Formula for Futility?; __ D. C. Mauchley1, J. K. Kirklin1, K. M. Wille2, K. F. Cornelius3, M. A. Tresler1, M. S. Blood4, E. D. Zavala5, J. J. Martinez6, W. C. Erwin7, S. C. Ballot1, C. W. Hoopes1. 1 _Surgery - Cardiovascular/Thoracic, University of Alabama at Birmingham, Birmingham, AL,_ 2 _Department of Medicine / Division of Pulmonary Allergy and Critical Care, University of Alabama at Birmingham, Birmingham, AL,_ 3 _Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL,_ 4 _Perioperative Services, University of Alabama at Birmingham, Birmingham, AL,_ 5 _Med - Pulmonary/Allergy/Critical Care, University of Alabama at Birmingham, Birmingham, AL,_ 6 _UAB General Surgery Residency, University of Alabama at Birmingham, Birmingham, AL,_ 7 _University of Alabama at Birmingham, Birmingham, AL_

**(1010)** Combined Heart-Kidney Transplant vs Heart Alone Transplant in Patients with Total Artificial Heart: Are they Viable?; __ J. Moriguchi, M. Kittleson, J. Patel, T. Aintablian, J. Kwan, E. Kransdorf, D. Geft, D. H. Chang, L. Czer, J. A. Kobashigawa, F. Arabia. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(1011)** Experience with Extracorporeal Membranous Oxygenation Support for Cardiocirculatory Arrest Following Acute Myocardial Infarction; __ A. F. Shaikh1, G. V. Gonzalez-Stawinski2, J. J. Squiers2, T. Chamogeorgakis2, J. C. MacHannaford2, A. E. Rafael2, R. Vallabhan2, J. E. Choi2, J. M. Schussler2, M. DiMaio2, R. C. Stoler2, B. Lima2. 1 _College of Medicine, Texas A &M University, Dallas, TX, _2 _Baylor University Medical Center, Dallas, TX_

**(1012)** Employment Status and Wait-List Outcomes in Patients Bridged with Left Ventricular Assist Devices; __ L. Meece, S. G. Al-Kindi, C. Bianco, B. Dhakal, M. Ginwalla, C. Elamm, G. H. Oliveira. _Harrington Heart and Vascular Institute, University Hospitals, Cleveland, OH_

**(1013)** Depression in Patients Undergoing Left Ventricular Assist Device Implantation; __ S. Lundgren, E. Raichlin, A. Selim, B. Lowes, R. Zolty, M. Moulton, J. Um, C. Poon. _University of Nebraska Medical Center, Omaha, NE_

**(1014)** Predicting Outcomes in Patients Requiring Extracorporeal Membrane Oxygenation; __ S. Wu1, M. Fong2, L. Saxon2, G. Fox3, L. Wiggins4, A. Hackmann4. 1 _Internal Medicine, University of Southern California, Los Angeles, CA,_ 2 _Cardiology, University of Southern California, Los Angeles, CA,_ 3 _University of Southern California, Los Angeles, CA,_ 4 _Cardiothoracic Surgery, University of Southern California, Los Angeles, CA_

**(1015)** Assessment of Lean Dorsal Muscle Surface Area by CT Scan and Effect on Outcomes in Heart Transplant Recipients: Results from a Single Center; __ S. Joseph, G. Gonzalez-Stawinski, J. Hasse, G. Saracino, M. Edens, J. Felius, A. Jamil, S. A. Hall, B. Lima. _Baylor University Medical Center, Dallas, TX_

**(1016)** Successful Bridge to Continuous-Flow Left Ventricular Assist Device Using Extracorporeal Membrane Oxygenation Support for INTERMACS Profile I Patients; __ K. L. Kerk1, T. E. Tan1, D. Sim2, C. P. Lim2, J. H. Tay1, C. L. Neo1, J. L. Tan1, C. Sivathasan1. 1 _Cardiothoracic Surgery, National Heart Centre, Singapore, Singapore,_ 2 _Cardiology, National Heart Centre, Singapore, Singapore_

**(1017)** Outcomes of Patients Who Require Temporary Mechanical Circulatory Support Prior to Left Ventricular Assist Device Placement; __ F. Mazzulla1, R. Cogswell2, J. Schultz1, A. Walts2, J. Misialek2, T. Thenappan2, M. Pritzker2, E. Missov2, C. M. Martin2, K. Liao3, R. John3. 1 _Department of Medicine, University of Minnesota, Minneapolis, MN,_ 2 _Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN,_ 3 _Department of Surgery, Division of Cardiovascular and Thoracic Surgery, University of Minnesota, Minneapolis, MN_

**(1018)** Predictors of Mortality in Cardiogenic Shock Patients Treated with Extra-Corporeal Cardiopulmonary Resuscitation; __ S. J. Stein1, H. Takayama2, A. R. Garan3, V. K. Topkara3, M. Salna1, J. Han1, P. A. Kurlansky4, M. Yuzefpolskaya3, M. A. Farr3, P. C. Colombo3, Y. Naka2, K. Takeda2. 1 _Columbia University, New York, NY,_ 2 _Department of Surgery, Division of Cardiothoracic Surgery, Columbia University, College of Physicians and Surgeons, New York, NY,_ 3 _Department of Medicine, Division of Cardiology, Columbia University, College of Physicians and Surgeons, New York, NY,_ 4 _Department of Surgery, Columbia University, College of Physicians and Surgeons, New York, NY_

**(1019)** Bridge to Bridge Strategy: The Challenging Task of Selecting Ideal VAD Candidates on Short Term Circulatory Support; __ D. Saeed, R. Wieloch, G. Petrov, B. Maxhera, M. Abdeen, N. Sadat, U. Boeken, A. Lichtenberg, A. Albert. _Cardiovascular Surgery, Heinrich-Heine University Dusseldorf, Düsseldorf, Germany_

**(1020)** Division of the Patient Selection Committee (PSC) Process into Two Segments Has Improved the Rigor, Efficiency and Satisfaction in the Selection Process; __ M. G. Dickinson, S. Lee, D. Fermin, K. Veine, T. Boeve, P. Wilton, A. Khaghani. _Frederik Meijer Heart & Vascular Institute, Spectrum Health, Grand Rapids, MI_

**(1021)** Is the Cardiac Allocation Score (CAS) a Predictor of Therapy Failure After HU Listing?; __ J. Sunavsky, B. Fujita, E. Prashovikj, S. Ensminger, J. Gummert, U. Schulz. _Heart and Diabetes Centre NRW, Ruhr University Bochum, Bad Oeynhausen, Germany_

**(1022)** Early RV Failure Is Much More Common Than Late RV Failure Post LVAD Implant; __ M. El Baba, V. Cotarlan, M. Bengaluru- Jayanna, J. Bhama, R. Chawla. _University of Iowa, Iowa City, IA_

**(1023)** Delivery During ECMO: A Single-Center Case Series; __ M. Morsolini1, S. Sciacca1, G. Panarello2, G. Martucci2, A. Bertani1, R. Longo3, P. Vitulo1, A. Arcadipane2, M. Pilato1. 1 _Department for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, IRCCS - ISMETT, Palermo, Italy,_ 2 _Department of Anesthesia and Intensive Care, IRCCS - ISMETT, Palermo, Italy,_ 3 _Service of Cardiovascular Perfusion, IRCCS - ISMETT, Palermo, Italy_

**(1024)** Pulmonary Artery Pulsatility Index as a Predictor of Right Ventricular Disfunction After Left Ventricular Assist Device Implantation; __ S. Mingo Santos, V. Moñivas Palomero, A. Durante Lopez, J. F. Oteo Dominguez, S. Vilches Soria, M. Gomez Bueno, F. Hernandez Perez, J. Goirigolzarri Artaza, L. Alonso Pulpon, S. Serrano Fiz, J. Segovia Cubero. _Cardiology, Hospital Puerta de Hierro Majadahonda, Majadahonda, Spain_

**(1025)** Preoperative Total Serum Bilirubin Is an Independent Predictor of Post LVAD Outcomes; __ L. H. Stein1, S. Zeigler1, W. Hiesinger1, Y. J. Woo1, D. Banerjee2, C. Hill3, R. Ha1. 1 _Department of Cardiothoracic Surgery, Stanford University, Stanford, CA,_ 2 _Department of Cardiovascular Medicine, Stanford University, Stanford, CA,_ 3 _Department of Anesthesiology, Perioperative, and Pain Medicine, Stanford University, Stanford, CA_

**(1026)** Veno- Arterial Extracorporeal Membrane Oxygenation as Bridge to LVAD Is Associated with Good Long Term Outcomes and Quality of Life; __ D. Miranda1, B. Magod2, K. Wilson2, R. Garberich2, K. Hryniewicz1. 1 _Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, MN,_ 2 _Minneapolis Heart Institute Foundation, Minneapolis, MN_

**(1027)** A Big (Clot) Problem! Extreme Obesity Is Associated with a Higher Incidence of Durable LVAD Thrombosis; __ A. Y. Lee1, B. Lima2, K. M. Tecson3, A. F. Shaikh4, S. Still5, J. Collier5, R. Baxter5, S. Carey6, G. V. Gonzalez-Stawinski7, S. A. Hall6, S. M. Joseph6. 1 _Department of Cardiovascular Disease, Baylor University Medical Center, Dallas, TX,_ 2 _Division of Cardiac Surgery, Department of Surgery, Baylor University Medical Center, Dallas, TX,_ 3 _Baylor Heart and Vascular Institute, Baylor Scott & White Research Institute, Dallas, TX, _4 _Texas A &M College of Medicine, Bryan, TX, _5 _Department of Surgery, Baylor University Medical Center, Dallas, TX,_ 6 _Center for Advanced Heart and Lung Disease, Baylor University Medical Center, Dallas, TX,_ 7 _Department of Cardiac and Thoracic Surgery, Baylor University Medical Center, Dallas, TX_

**(1028)** Moderate Baseline Pulmonary Hypertension with a Robust Reduction in Mean Pulmonary Artery Pressures Post-LVAD Is Associated with Improved 1-Year Survival; __ S. A. Smith1, B. Lampert1, R. Emani1, R. Hasson2, B. Whitson2, A. Hasan1, A. Kilic2. 1 _Internal Medicine, The Ohio State University, Columbus, OH,_ 2 _Cardiothoracic Surgery, The Ohio State University, Columbus, OH_

**(1029)** AST/ALT (DeRitis)-Ratio Predicts Mid- and Longterm Mortality After LVAD Implantation; __ H. Carstens1, A. Koch1, N. Pizanis1, J. Heckmann1, P. Lüdike2, T. Rassaf2, M. Kamler1. 1 _Thoracic Transplant, University Essen, Essen, Germany,_ 2 _Cardiology, University Essen, Essen, Germany_

**(1030)** The Story on Extracorporeal Membrane Oxygenation (ECMO) Directly to Mechanical Circulatory Support or to Heart Transplantation; __ D. Geft, M. Kittleson, J. Patel, T. Aintablian, R. Levine, M. Hashimoto, E. Kransdorf, D. H. Chang, L. Czer, D. Ramzy, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(1031)** ECMO Use in INTERMACS 1 Patients as a Bridge to LVAD with Intention to Transplant versus Bridge to Direct Heart Transplant. Single Center Experience; __ J. I. Gentile1, M. R. Molina1, P. Atluri1, J. E. Rame1, J. W. Wald2, E. Y. Birati3, L. R. Goldberg4, R. McLean1, M. I. Acker1, C. A. Bermudez1. 1 _Division of Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA,_ 2 _Clinical Medicine, University of Pennsylvania, Philadelphia, PA,_ 3 _Cardiology, University of Pennsylvania, Philadelphia, PA,_ 4 _Heart Failure and Cardiac Transplant Center, University of Pennsylvania, Philadelphia, PA_

**(1032)** Predictors of Survival in Patients Undergoing VA-ECMO and the Utility of the SAVE Score in a UK Transplant Population; __ E. J. McKay1, P. S. Chaggar1, K. Heyes1, P. Foden2, S. G. Williams1, J. Bernard1, N. Yonan1, R. Venkateswaran1, S. M. Shaw1. 1 _The Transplant Unit, University Hospital South Manchester, Manchester, United Kingdom,_ 2 _Medical Statistics, University Hospital South Manchester, Manchester, United Kingdom_

**(1033)** Psychosocial Factors and Outcomes with Left Ventricular Assist Device Therapy; __ S. Lundgren, R. High, C. Poon, E. Raichlin, R. Zolty, A. Burdorf, J. Um, B. Lowes. _University of Nebraska Medical Center, Omaha, NE_

**(1034)** Usefulness of the INTERMACS Scale to Predict Outcomes in Patients Undergoing Ventricular Assist Device Implant Through Less Invasive Surgery; __ S. V. Rojas, J. S. Hanke, A. Uribarri, M. Avsar, G. Dogan, E. Deniz, M. Ricklefs, A. Haverich, J. D. Schmitto. _Department of Cardiothoracic-, Transplantation- and Vascular Surgery, Hannover Medical School, Hannover, Germany_

**(1035)** Pulmonary Vascular Resistance Does Not Impact Wait-List Mortality in Patients Bridged with Continuous Flow Left Ventricular Assist Devices; __ S. G. Al-Kindi, B. Dhakal, M. Ginwalla, C. ElAmm, B. Sareyyupoglu, G. H. Oliveira. _University Hospitals Cleveland Medical Center, Cleveland, OH_

**(1036)** Correlation Between Skeletal Muscle Mass and Other Prognostic Markers in Left Ventricular Assist Device Recipients; __ L. M. Teigen1, A. J. Kuchnia1, C. P. Earthman1, A. N. Walts2, R. John3, R. Cogswell2. 1 _Food Science and Nutrition, University of Minnesota, St. Paul, MN,_ 2 _Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN,_ 3 _Department of Surgery, Division of Cardiovascular and Thoracic Surgery, University of Minnesota, Minneapolis, MN_

**(1037)** Outcomes of Veno-Arterial Extracorporeal Membrane Oxygenation in Cardiogenic Shock in the Elderly. Large Single Center Experience; __ J. I. Gentile1, P. Atluri1, N. D. Desai1, P. Vallabhajosyula1, J. W. Wald2, J. E. Rame1, J. T. Gutsche3, J. Horak3, M. I. Acker1, C. A. Bermudez1. 1 _Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA,_ 2 _Clinical Medicine, University of Pennsylvania, Philadelphia, PA,_ 3 _Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA_

**(1038)** Extremes of Body Mass Index Should Not Preclude Left Ventricular Assist Device Implantation in the Current Era; __ A. McDavid1, A. Kilic2, J. Gustafson1, S. Smith1, B. Lampert1, B. A. Whitson1, A. Hasan1, A. Kilic1. 1 _The Ohio State University, Columbus, OH,_ 2 _The University of Pennsylvania, Philadelphia, PA_

**(1039)** Psoas Muscle Cross-Sectional Area Predicts Increased Resource Utilization After Left Ventricular Assist Device Placement; __ R. B. Hawkins, J. Mehaffey, T. Welch, S. Mazimba, G. Ailawadi, L. Yarboro. _University of Virginia, Charlottesville, VA_

**(1040)** Ventricular Assist Device Support for Ischemic Cardiomyopathy: A Single-Center Experience in Japan; __ K. Kuroda1, Y. Kumai1, H. Sunami1, S. Nakajima1, T. Sato1, O. Seguchi1, M. Yanase1, Y. Matsumoto2, H. Hata2, T. Fujita2, J. Kobayashi2, N. Fukushima1. 1 _Transplantation, National Cerebral and Cardiovascular Center, Osaka, Japan,_ 2 _Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Osaka, Japan_

**(1041)** Effect of Preoperative Small Left Ventricle on Patients with Chronic Heart Failure Undergoing Implantation of Long-Term Continuous Flow Ventricular Assist Devices: Comparative Analysis of HeartMate II and HeartWare Devices; __ M. Kawabori, C. Kurihara, T. Sugiura, A. B. Civitello, W. E. Cohn, O. H. Fraizer, J. A. Morgan. _Texas Heart Institute, Baylor College of Medicine, Houston, TX_

**(1042)** Right Atrial to Pulmonary Capillary Wedge Pressure Ratio as Predictor for Postoperative Outcomes in Left Ventricular Assist Device Implantation; __ G. Bhat, A. Ali, G. Yost, A. Tatooles. _Heart Institute, Advocate Christ Med Center, Oak Lawn, IL_

**(1043)** WITHDRAWN

**(1044)** Veno-Veno-Arterial Extracorporeal Membrane Oxygenation in Patients with Respiratory Failure; __ F. Ius1, W. Sommer1, I. Tudorache1, M. Avsar1, T. Siemeni1, D. Böthig1, J. Puntigam1, J. Optenhöfel1, T. Welte2, A. Haverich1, M. Hoeper2, C. Kühn1, G. Warnecke1. 1 _Department of Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany,_ 2 _Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany_

**(1045)** The Accuracy of Physical Exam Compared to RHC in LVAD Patients; __ E. C. Anyanwu1, A. Bhatia1, D. M. Tehrani1, A. Deshmukh1, D. Rodgers2, S. Adatya2, N. Sarswat2, G. Kim2, G. Sayer2, T. Ota3, V. Jeevanandam3, N. Uriel2. 1 _Internal Medicine, University of Chicago, Chicago, IL,_ 2 _Advanced Heart Failure, University of Chicago, Chicago, IL,_ 3 _Cardiac Surgery, University of Chicago, Chicago, IL_

**(1046)** ECPR as a Tool to Improve Outcome of Refractory Cardiac Arrest; __ D. Pabst1, A. El-Banayosy2, B. Soleimani1, C. Brehm1. 1 _Heart and Vascular Institute, Penn State Milton S. Hershey Medical Center, Hershey, PA,_ 2 _INTEGRIS Baptist Medical Center, Oklahoma City, OK_

**(1047)** Monitoring Aspirin Levels in Patients with LVAD; __ R. Hards, G. Edwards, M. Hedger, A. R. Simon. _Transplant and Mechanical Circulatory Support, Harefield Hospital, uxbridge, United Kingdom_

**(1048)** Increased Post-Operative Mortality in Patients Undergoing Coronary Artery Bypass Grafting During Left Ventricular Assist Device Implantation; __ P. Mehta1, C. Juricek2, T. Imamura3, S. Adatya3, N. Sarswat3, G. Kim3, J. Raikhelkar3, T. Ota2, V. Jeevanandam2, G. Sayer3, N. Uriel3. 1 _Internal Medicine Residency Program, Department of Medicine, University of Chicago, Chicago, IL,_ 2 _Section of Cardiothoracic Surgery, University of Chicago, Chicago, IL,_ 3 _Section of Cardiology, University of Chicago, Chicago, IL_

**(1049)** Blood Pressure Measurement in Patients with a HeartMate 3; __ J. Fischer, A. L. Meyer, K. Jawad, A. Addas, M. Zoric, S. Lehmann, J. Hahn, F. W. Mohr, J. Garbade. _Leizpig Heart Center, Leizpig, Germany_

**(1050)** Effect of LVAD Speed Titration on Microvascular Perfusion; __ I. Tchoukina, M. D. Kozak, A. N. Iness, J. R. Coleman, S. Gunda, M. C. Smallfiled, K. B. Shah. _Virginia Commonwealth University, Richmond, VA_

**(1051)** Peak Oxygen Consumption and Six-Minute Walk Distance in Patients with an HVAD Left Ventricular Assist Device at Discharge from Cardiac Rehabilitation; __ T. Schmidt1, B. Bjarnason-Wehrens2, M. Hannig1, M. Altesellmeier1, S. Schulte-Eistrup1, D. Willemsen1, N. Reiss1. 1 _Schüchtermann Klinik, Bad Rothenfelde, Germany,_ 2 _Department for Preventive and Rehabilitative Sport and Exercise Medicine, Institute for Cardiology and Sports Medicine, German Sports University Cologne, Cologne, Germany_

**(1052)** Absence of Valvular Disease Following Left Ventricular Assist Device Implantation Is Associated with Improved Midterm Survival; __ T. Ota1, A. Tanaka1, H. Kitahara1, T. Song1, D. Onsager1, J. Raikhelkar2, G. Kim2, N. Sarswat2, S. Adatya2, G. Sayer2, N. Uriel2, V. Jeevanandam1. 1 _Surgery, The University of Chicago, Chicago, IL,_ 2 _Medicine, The University of Chicago, Chicago, IL_

**(1053)** High Grade Mitral Regurgitation After a Left Ventricular Assist Device May Adversely Affect Survival; __ A. Sotolongo. _Department of Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA_

**(1054)** Red Cell Distribution Width and Outcomes After Ventricular Assist Device Implantation; __ S. Sundararajan1, J. N. Upshaw2, M. S. Kiernan2, D. DeNofrio2, G. S. Couper3, A. R. Vest2. 1 _Department of Medicine, Mount Auburn Hospital, Cambridge, MA,_ 2 _Division of Cardiology, Tufts Medical Center, Boston, MA,_ 3 _Division of Cardiac Surgery, Tufts Medical Center, Boston, MA_

**(1055)** Cardiac Output and Oxygen Kinetic in Patients with Left Ventricular Assist Device; __ S. Paolillo1, C. Vignati2, A. Apostolo3, N. Bonini4, N. Bruno4, S. Scuri4, P. Agostoni4. 1 _SDN, IRCCS, Naples, Italy,_ 2 _Centro Cardiologico Monzino, IRCCS, Milano, Italy,_ 3 _Centro Cardiologico Monzino, Milano, Italy,_ 4 _Centro Cardiologico Monzino, IRCCS, Milan, Italy_

**(1056)** Exercise-Induced Elevation of Left Atrial Pressure Limits Functional Capacity in LVAD Patients: Insights from LA Pressure Sensor Monitoring; __ J. Abraham. _Center for Advanced Heart Disease, Providence Heart and Vascular Institute, Portland, OR_

**(1057)** Log Files: A Vital Patient Care Tool; __ H. R. Smith, D. J. Sato, K. J. Mesa, K. A. Ihnken, A. T. Coletti. _Mechanical Heart Program, Providence Sacred Heart Medical Center, Spokane, WA_

**(1058)** Outcomes of Veno Arterial Extracorporeal Membrane Oxygenation at University of Kentucky Based on Etiology of Cardiogenic Shock; __ A. R. Kolodziej, A. Burchett, T. A. Tribble, R. Charnigo, S. Smyth, M. Guglin. _Cardiology, University of Kentucky, Lexington, KY_

**(1059)** Acute Hemodynamic Effects of Cardiac Resynchronization Therapy in Patients with Left Ventricular Assist Device; __ J. M. Joly, E. Andrikopoulou, C. P. Lin, D. Acharya, S. V. Pamboukian, S. D. Prabhu, I. N. Rajapreyar, J. A. Tallaj, V. Kumar. _University of Alabama at Birmingham, Birmingham, AL_

**(1060)** A Longitudinal Analysis of NT-proBNP After LVAD Implantation; __ C. Falls, G. Lolay, K. Kido, B. George, H. Omar, M. Guglin. _University of Kentucky, Lexington, KY_

**(1061)** Configuration of Extracorporeal Circulation and Association with Outcomes; __ R. A. Rose1, V. Kagan2, R. M. Piech2, A. F. Linden3, N. Uriel4, V. Jeevanandam2, T. H. Song2. 1 _ECMO / MCS Services, University of Chicago Medicine, Chicago, IL,_ 2 _Cardiothoracic Surgery, University of Chicago Medicine, Chicago, IL,_ 3 _Pediatric Surgery, University of Chicago Medicine, Chicago, IL,_ 4 _Cardiology, University of Chicago Medicine, Chicago, IL_

**(1062)** Lactic Acid Is the Most Important Factor Predicting Survival on VA ECMO; __ A. Kolodziej1, A. Burchett1, T. Tribble1, A. Y. Grigorian2, M. Guglin1. 1 _Cardiology, University of Kentucky, Lexington, KY,_ 2 _Gastroenterology, University of Kentucky, Lexington, KY_

**(1063)** Biventricular Pacing Has No Acute Hemodynamic Benefit Over Right Ventricular Pacing or Intrinsic Rhythm in LVAD Patients; __ V. Cotarlan1, F. Johnson1, J. Franzwa1, C. Inampudi1, U. Emerenini1, R. Tandon1, R. Tahir2, Y. Nabeel1, J. Goerbig3, K. Light-McGroary1, G. Goldsmith1, M. Giudici1. 1 _Univ of Iowa Hospital, Iowa City, IA,_ 2 _Geisinger Medical Center, Danville, PA,_ 3 _Iowa Heart Center, Des Moines, IA_

**(1064)** Impact of Change in Body Mass Index on Outcomes After Left Ventricular Assist Device Implantation in Obese Patients; __ A. Mano. _Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Osaka, Japan_

**(1065)** Not All INTERMACS Level 1's Are the Same: Survival After Total Artificial Heart Implantation with or without Temporary Circulatory Support; __ H. J. Reich1, D. Ramzy2, J. Mirocha2, M. A. De Robertis2, J. Chung2, F. Esmailian2, D. Chang3, J. Moriguchi3, L. Czer3, A. Trento2, F. Arabia2. 1 _Surgery, Cedars-Sinai Medical Center, Los Angeles, CA,_ 2 _Cardiothoracic Surgery, Cedars-Sinai Heart Institute, Los Angeles, CA,_ 3 _Cardiology, Cedars-Sinai Heart Institute, Los Angeles, CA_

**(1066)** Effect of Arterial Cannulation Site on Cerebral Blood Flow During Peripheral Venoarterial Extracorporeal Membrane Oxygenation; __ H. Ikegami1, J. Z. Willey2, D. Yoshioka1, P. A. Kurlansky1, A. R. Garan3, V. K. Topkara3, M. Yuzefpolskaya3, H. Takayama1, P. C. Colombo3, Y. Naka1, K. Takeda1. 1 _Surgery, Columbia University, New York, NY,_ 2 _Neurology, Columbia University, New York, NY,_ 3 _Medicine, Columbia University, New York, NY_

**(1067)** Longitudinal Neutrophil to Lymphocyte Ratio Assessment After Left Ventricular Assist Device Implantation; __ G. Yost, K. Ibrahim, A. Tatooles, G. Bhat. _Heart Institute, Advocate Christ Med Center, Oak Lawn, IL_

**(1068)** The Hemodynamic Effects of Concomitant Tricuspid Valve Repair and Left Ventricular Assist Device Implantation; __ J. Nnanabu1, D. Rodgers1, A. Nguyen1, N. Sarswat1, J. Raikehlkar1, S. Adatya1, G. H. Kim1, D. Medvedofsky1, T. Ota1, T. Song1, D. Burkhoff2, R. M. Lang1, V. Jeevanandam1, G. Sayer1, N. Uriel1. 1 _University of Chicago, Chicago, IL,_ 2 _Heartware International, Inc, Framingham, MA_

**(1069)** WITHDRAWN

**(1070)** Impact of Chronic Obstructive Pulmonary Disease on Early Right Ventricular Dysfunction and Failure Following Left Ventricular Assist Device Implantation; __ R. M. Hasson Charles1, S. D. Moffatt-Bruce2, E. Cerier3, S. A. Smith4, B. C. Lampert4, A. McDavid1, B. A. Whitson1, M. K. Essandoh5, A. Kilic1. 1 _Cardiothoracic Surgery, The Ohio State University, Columbus, OH,_ 2 _Thoracic Surgery, The Ohio State University, Columbus, OH,_ 3 _Medicine, The Ohio State University College of Medicine, Columbus, OH,_ 4 _Cardiology, The Ohio State University, Columbus, OH,_ 5 _Anesthesia, The Ohio State University, Columbus, OH_

**(1071)** The Changing Flow Patterns in Carotid Arteries and the Effect of Aortic Valve Opening on Carotid and Middle Cerebral Arteries in LVAD Patients; __ M. Pac1, M. Karahan1, S. Kocabeyoglu1, Z. Catav1, D. Sert1, B. Demirkan2, M. Tola3, O. Kursun4, E. Aygun1, U. Kervan1. 1 _Cardiovascular Surgery, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey,_ 2 _Cardiology, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey,_ 3 _Radiology, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey,_ 4 _Neurology, Ankara Numune Hospital, Ankara, Turkey_

**(1072)** The Influence of a Dedicated and Protocolized Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) Strategy on Patient Outcomes: A Before and After Study; __ R. Williams1, S. Coffin2, S. Derryberry1, M. Djunaidi1, A. Shah1, S. Huang3, S. McGrane4, C. Cropsey4, C. Henson4, W. Costello4, J. Kennedy4, E. Haddad5, M. Danter1. 1 _Cardiac Surgery, Vanderbilt University Medical Center, Nashville, TN,_ 2 _Cardiology, Maine Health Partners MaineHealth Cardiology-Scarborough, Scarborough, ME,_ 3 _Biostatistics, Vanderbilt University Medical Center, Nashville, TN,_ 4 _Anesthesiology, Vanderbilt University Medical Center, Nashville, TN,_ 5 _Cardiology, Vanderbilt University Medical Center, Nashville, TN_

**(1073)** Acoustic Characterisation of the HeartWare Ventricular Assist Device as a Novel Non-Invasive Diagnostic and Management Technique; __ M. Shah1, D. Bull1, P. Markey1, H. C. Chew2, C. Cheong1, D. Robson3, P. MacDonald3, K. Dhital2. 1 _Faculty of Medicine, University of New South Wales, Sydney, Australia,_ 2 _Department of Cardiothoracic Surgery, St Vincent's Hospital, Sydney, Australia,_ 3 _Department of Cardiology, St Vincent's Hospital, Sydney, Australia_

**(1074)** Left Ventricular Reverse Remodeling Is Associated with LVAD Speed Indexed for Body Surface Area but Not Raw Pump Speed in the Heartmate II Device; __ S. Airhart, H. Kassis, K. Cherukuri, R. Agarwal, R. L. Benza, R. J. Moraca, S. H. Bailey, A. Raina. _Cardiovascular Institute, Allegheny General Hospital, Pittsburgh, PA_

**(1075)** What Factors Influence Right Ventricular Function Improvement in the Setting of Pulmonary Arterial Pressure Normalization After Left Ventricular Assist Device Placement?; __ A. Nikolova, D. Geft, D. H. Chang, J. S. Chung, R. Jocson, T. Aintablian, E. Passano, L. Czer, J. A. Kobashigawa, J. Moriguchi, F. Arabia. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(1076)** Analysis of Post-LVAD Clinical Pathways; __ F. Movahedi1, L. Carey2, Y. Zhang3, R. Padman4, J. Antaki5, M. Kanwar6. 1 _Electrical Engineering, University of Pittsburgh, Pittsburgh, PA,_ 2 _Biomedical Engineering, University of Pittsburgh, Pittsburgh, PA,_ 3 _Heinz College, Carnegie Mellon University, Pittsburgh, PA,_ 4 _University of Texas at Austi, Pittsburgh, PA,_ 5 _Mechanical Engineering, University of Pittsburgh, Pittsburgh, PA,_ 6 _Allegheny General Hospital, Division of Cardiology, University of Pittsburgh, Pittsburgh, PA_

**(1077)** Patients with End-Stage Heart Failure: Two Takes on Health Engagement; __ L. C. Lohmueller1, C. K. McIlvennan2, M. Kanwar3, J. F. Antaki1. 1 _Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA,_ 2 _Cardiovascular Institute, University of Colorado, Denver, Denver, CO,_ 3 _Cardiology, Allegheny General Hospital, Pittsburgh, PA_

**(1078)** The Ramp Fingerprint: LVAD Patients Have Similar Filling Pressures and Speed Change Responses at Repeat Ramp Tests; __ T. Imamura, D. Rodgers, S. Adatya, N. Sarswat, G. Kim, J. Raikhelkar, T. Ota, V. Jeevanandam, G. Sayer, D. Burkhoff, N. Uriel. _University of Chicago, Chicago, IL_

**(1079)** Validity of Non-Invasive Measures of Pulsatility During Continuous Flow LVAD Support; __ S. Rangasamy, M. D. Cruz, S. Madan, O. Saeed, D. B. Sims, J. J. Shin, U. P. Jorde, S. R. Patel. _Cardiology, Montefiore Medical Center, Bronx, NY_

**(1080)** Noninvasive Assessment of Lung Fluid Percentage in Patients with Left Ventricular Assist Devices; __ G. H. Kim1, D. Rodgers1, T. Imamura1, A. Nguyen1, B. Chung1, N. Sarswat1, J. Raikhelkar1, S. Adatya1, G. Sayer1, R. Abbo2, D. Burkhoff3, N. Uriel1. 1 _University of Chicago, Chicago, IL,_ 2 _Sensible Medical, Netanya, Israel,_ 3 _Department of Medicine, Columbia University, New York, NY_

**(1081)** Beat-to-Beat Detection of Aortic Valve Opening in Continuous Flow LVAD Patients with Irregular Cardiac Rhythm and with Hemodynamic Maneuvers; __ R. Clifford1, D. Robson1, C. Gross2, F. Moscato2, H. Schima2, P. S. Macdonald1, P. Jansz1, C. S. Hayward1. 1 _Heart Failure and Transplant Unit, St Vincent's Hospital, Sydney, Australia,_ 2 _Medical University of Vienna, Vienna, Austria_

**(1082)** Pre-Operative Predictors of Mortality in Adults Supported with Short-Term Continuous Flow Ventricular Assist Devices; __ S. J. Bozso1, J. Conway2, D. H. Freed1, B. Martin1, R. G. MacArthur1, H. Buchholz3. 1 _Division of Cardiac Surgery, University of Alberta, Edmonton, AB, Canada,_ 2 _Division of Cardiology, University of Alberta, Edmonton, AB, Canada,_ 3 _Division of Pediatric Cardiac Surgery, University of Alberta, Edmonton, AB, Canada_

**(1083)** An Expanded Assessment of Indications for Impella RP: A Large Single Center Experience RVAD Experience; __ M. B. Anderson, T. Robbins, A. Tuluca, C. Malaczewski, D. L. Morris. _Cardio-Thoracic Surgery, Albert Einstein Medical Center, Philadelphia, PA_

## Nursing, Health Sciences, Allied Health

(Coronado Foyer)

**Poster Discussants:** Tiffany M Buda, BSN (USA), Annette J DeVito-Dabbs, PhD, RN (USA), Connie White-Williams, PhD, RN (USA), Rachel A Zomak, RN, MS (USA)

**(1084)** Single Center Observation on the Impact of Objective Identification of Functional Frailty in LVAD Patients; __ E. Colclough, J. Webster, K. McCants, T. Hrobowski, A. Yehya, A. Krishnamoorthy, A. Darlington, D. A. Dean. _Advanced Heart Failure, Piedmont Heart, Atlanta, GA_

**(1085)** Psychosocial Screening in Pediatric Heart Transplant Recipients and Their Families; __ M. Cousino1, K. Rea1, M. Zamberlan2, J. Jordan1, S. Eder1, E. Fredericks1, K. Schumacher1. 1 _Pediatrics, C.S. Mott Children's Hospital, Ann Arbor, MI,_ 2 _Cardiac Surgery, C.S. Mott Children's Hospital, Ann Arbor, MI_

**(1086)** The Role of Early Nutrition Screening and Intervention in LVAD Therapy; __ L. Beal, J. Webster, K. McCants, T. Hrobowski, A. Yehya, A. Krishnamoorthy, A. Darlington, D. A. Dean. _Advanced Heart Failure, Piedmont Heart, Atlanta, GA_

**(1087)** Putting Your Best Foot Forward: The High Incidence of Foot Fractures After Lung Transplantation; __ L. M. Fuller1, H. Curry2, K. Hackman3, G. Snell4, L. Kimmel1. 1 _Physiotherapy, Alfred Hospital, Melbourne, Australia,_ 2 _Orthopaedic Surgery, Alfred Hospital, Melbourne, Australia,_ 3 _Endocrinology Department, Alfred Hospital, Melbourne, Australia,_ 4 _Lung Transplant Services, Alfred Hospital, Melbourne, Australia_

**(1088)** The ERO Form: The European Retrieval of Organs Initiative to Standardise Essential Information; __ C. Ellis, K. Morley. _Transplant Unit, Papworth Hospital, Cambridge, United Kingdom_

**(1089)** Tick, Tock - Shrinking Ischemic Times in Pediatric Heart Transplantation Through Process Standardization; __ S. L. Stark1, C. Chin1, J. Gossett2, A. Lorts1, T. D. Ryan1, I. Wilmot1, J. L. Jefferies1, R. Bryant III1. 1 _Heart Institute, Cincinnati Children's Hosp Med Ctr, Cincinnati, OH,_ 2 _Cincinnati Children's Hosp Med Ctr, Cincinnati, OH_

**(1090)** Management of a Counterpulsation Device Outside of the Intensive Care Unit; __ H. Costantini1, C. Juricek1, V. Kagan1, T. Song1, D. Onsager1, T. Ota1, N. Uriel2, V. Jeevanandam1. 1 _Cardiothoracic Surgery, University of Chicago, Chicago, IL,_ 2 _Cardiology, University of Chicago, Chicago, IL_

**(1091)** Yes We Can. A Multidisciplinary, Trans Center and Multi Device Journey of Pediatric Patient on the Road to Heart Transplantation; __ A. Wypych-Zych1, K. Egert1, S. Mather1, R. Hards1, M. Hedger1, B. Zych2, D. Garcia2, A. R. Simon3. 1 _Intensive Care Unit, Royal Brompton and Harefield Foundation Trust, Harefield, United Kingdom,_ 2 _Cardio-Thoracic Transplantation & Mechanical Circulatory Support, Royal Brompton and Harefield Foundation Trust, Harefield, United Kingdom, _3 _Cardio-Thoracic Transplantation & Mechanical Cirulatory Support, Royal Brompton and Harefield Foundation Trust, Harefield, United Kingdom_

**(1092)** Obstacles to Acquiring Quality of Life Assessments for Pediatric Ventricular Assist Device Support: Perspectives from VAD Coordinators; __ B. M. Hawkins1, M. Priest2, J. Murray3, B. Elias4, M. Mehegan5, J. Lantz6, A. Shubert7, R. Cantor8, D. Koehl9, K. Uzark10. 1 _Cardiology, Boston Children's Hospital, Boston, MA,_ 2 _Cardiology, Alfred I. duPont Hospital for Children, Wilmington, DE,_ 3 _Cardiology, Lucile Packard Children's Hospital, Stanford, CA,_ 4 _Cardiology, Texas Children's Hospital, Houston, TX,_ 5 _Cardiology, St. Louis Children's Hospital, St. Louis, MO,_ 6 _Cardiology, Dallas Children's Hospital, Dallas, TX,_ 7 _Cardiology, Cincinnati Children's Hospital, Cincinnati, OH,_ 8 _The University of Alabama at Birmingham, Birmingham, AL,_ 9 _University of Alabama and Birmingham, Birmingham, AL,_ 10 _Cardiology, University of Michigan Congenital Heart Center, Ann Arbor, MI_

**(1093)** Do Heart Transplant Centers Have a Multidisciplinary Team as Indicated by ISHLT Guidelines? Findings from the International BRIGHT Study; __ M. Cajita1, E. Baumgartner2, L. Berben2, K. Denhaerynck2, R. Helmy2, S. Schönfeld2, G. Berger2, C. Vetter2, F. Dobbels3, C. L. Russell4, S. M. De Geest2, O. the BRIGHT Study Team5. 1 _School of Nursing, Johns Hopkins University, Baltimore, MD,_ 2 _Institute of Nursing Science, University of Basel, Basel, Switzerland,_ 3 _Academic Center for Nursing and Midwifery, KU Leuven, Leuven, Belgium,_ 4 _School of Nursing and Health Studies, University of Missouri-Kansas City, Kansas City, MO,_ 5 _University of Basel, Basel, Switzerland_

**(1094)** Utilization of Transverse Abdominis Plexus Block for Treatment of Left Ventricular Assist Device Associated Driveline Pain / Abdominal Pain Refractory to Conventional Multi-Modal Therapy: A Case Series; __ A. Conte, J. Hajj, S. Yang, E. Passano, H. Barone, D. Chang, F. Esmailian, L. Czer, J. Kobashigawa, J. Moriguchi, F. Arabia. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(1096)** Mechanical Circulatory Support Caregiver Gender Burden and Benefit: Is There a Difference?; __ B. Coleman, H. Barone, H. Aronow, C. Runyan, J. Hajj, N. Huie, E. Passano, L. Czer, J. A. Kobashigawa, J. Moriguchi, F. Arabia. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(1097)** Paird Donor Exchange in Lung Transplantation-Attitude Survey; __ C. Yokoyama, M. Morioka, S. Tanaka, K. Miyoshi, Y. Sahara, T. Oto. _Lung Transplant Unit, Organ Transplant Center, Okayama University Hospital, Okayama, Japan_

**(1098)** Does Caring for Heart and Lung Transplant Patients Lead to Psychological Stress in Multi-Disciplinary Care Teams?; __ S. A. Carey, J. W. Roden-Foreman, M. M. Bennett, J. Felius, S. A. Hall, A. Warren. _Baylor University Medical Center, Dallas, TX_

**(1099)** Got: The Psychological Impact of Hallucinations Whilst in Intensive Care - The New Zealand Heart and Lung Transplant Experience; __ L. Painter, I. S. Fontanilla. _Heart/Lung Transplant, Auckland District Health Board, Auckland, New Zealand_

**(1100)** Implementing Practices to Improve Self-Care Among Caregivers of Patients with Mechanical Circulatory Support; __ H. Barone, B. Coleman, H. Aronow, C. Runyan, J. Hajj, N. Huie, E. Passano, L. Czer, J. A. Kobashigawa, J. Moriguchi, F. Arabia. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(1101)** PROMOTED TO MINI ORAL

**(1102)** Fear of Graft Rejection and Psychological Distress One to Five Years After Lung Transplantation - A Multicentre Study; __ M. Lundmark1, M. Claëson2, M. Almgren1, A. Forsberg3. 1 _The Thoracic Intensive Care Unit, The Skåne University Hospital, Lund, Sweden,_ 2 _The Department of Transplantation and Cardiology, The Sahlgrenska University Hospital, Lund, Sweden,_ 3 _Institue of Health Sciences, Lund University, Lund, Sweden_

**(1103)** Chronic Pain One and Four Years After Heart Transplantation - A Multicentre Study; __ M. Almgren1, M. Lundmark1, A. Lennerling2, A. Forsberg3. 1 _The Thoracic Intensive Care Unit, Skåne University Hospital, Lund, Sweden,_ 2 _The Transplant Unit, The Sahlgrenska University Hospital, Gothenburg, Sweden,_ 3 _Institue of Health Sciences, Lund University, Lund, Sweden_

**(1104)** Symptom Prevalence and Symptom Distress One to Five Years After Lung Transplantation - A Multicentre Study; __ M. Lundmark1, M. Claëson2, M. Almgren1, A. Forsberg3. 1 _The Thoracic Intensive Care Unit, The Skåne University Hospital, Lund, Sweden,_ 2 _The Department of Transplantation and Cardiology, The Skåne University Hospital, Lund, Sweden,_ 3 _Institue of Health Sciences, Lund University, Lund, Sweden_

## Pulmonary Hypertension

(Harbor Foyer)

**Poster Discussants:** Rachel M Crackett, MSc (United Kingdom), Chandra Kunavarapu, MD (USA), Fabiana G Marcondes-Braga, MD, PhD (Brazil)

**(1106)** Right Ventricular Dysfunction Is the Strongest Determinant of Abnormal Left Ventricular Ejection Fraction in Pulmonary Arterial Hypertension; __ T. Meeran, J. R. PO, A. Elapavaluru, R. L. Benza, A. Raina. _Cardiovascular Institute, Allegheny General Hospital, Pittsburgh, PA_

**(1107)** Comparison of Indirect Fick and Thermodilution Cardiac Output with Right Ventricular Function in Pulmonary Hypertension; __ A. Al-Khodair, M. Y. Tsang, N. W. Brunner. _Cardiology, University of British Columbia, Vancouver, BC, Canada_

**(1108)** RVOT-VTI/PASP a Novel Non-Invasive Metric of Pulmonary Arterial Compliance Differs Across the Spectrum of Pulmonary Hypertension; __ A. Fox1, M. S. Tanna1, P. T. Bhattacharya1, G. S. Troutman1, F. Mao1, J. Menachem1, E. Y. Birati1, P. R. Forfia2, A. Vaidya2, J. A. Mazurek1. 1 _Univ of Pennsylvania, Philadelphia, PA,_ 2 _Temple University Hospital, Philadelphia, PA_

**(1109)** Transition from Parental Prostacyclin Therapy to Oral Selexipag in Pulmonary Arterial Hypertension: A Single Center, Case Series; __ E. Mims, D. Poch, D. Papamatheakis, T. Fernandes, S. Lombardi, L. Santana, N. H. Kim. _Pulmonary and Critical Care, UCSD, San Diego, CA_

**(1110)** The Recent Prognosis and Treatment of Idiopathic and Heritable Pulmonary Arterial Hypertension; The Report from Single Pulmonary Hypertension Center in Japan; __ H. Maki1, M. Hatano2, S. Minatsuki1, I. Komuro1. 1 _Cardiovascular Medicine, University of Tokyo, Tokyo, Japan,_ 2 _Therapeutic Strategy for Severe Heart Failure, University of Tokyo, Tokyo, Japan_

**(1111)** RVOT-VTI/PASP Is a Novel Noninvasive Parameter of Pulmonary Artery Compliance and Improves After Treatment with Pulmonary Hypertension-Specific Therapy ; __ M. S. Tanna1, A. Fox1, G. S. Troutman1, P. T. Bhattacharya1, J. N. Menachem1, F. Mao1, E. Y. Birati1, P. R. Forfia2, A. Vaidya2, J. A. Mazurek1. 1 _University of Pennsylvania, Philadelphia, PA,_ 2 _Temple University, Philadelphia, PA_

**(1112)** WITHDRAWN

**(1113)** Left Ventricular Assist Device Improves Type II Pulmonary Hypertension with High Pulmonary Vascular Resistance; __ A. Selim1, E. Raichlin1, A. Burdorf1, J. Um2, A. Siddique2, M. Moulton2, B. D. Lowes1, R. Zolty1. 1 _Cardiology, University of Nebraska Medical Center, Omaha, NE,_ 2 _Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE_

**(1114)** Clinical Characteristics and Survival in Pulmonary Hypertension Due to Chronic Lung Disease; __ K. Prins, L. Rose, C. Carlson, M. Pritzker, K. E. Weir, F. Kazmirczak, T. Thenappan. _Medicine- Cardiology, University of Minnesota, Minneapolis, MN_

**(1115)** Effects of Ambulatory Inhaled Nitric Oxide on Exercise Induced Increases in Pulmonary Pressures; __ R. A. Davey1, A. Raina2, R. L. Benza2. 1 _Division of Cardiology, Western University, London, ON, Canada,_ 2 _Cardiovascular Institute, Allegheny General Hospital, Pittsburgh, PA_

**(1116)** WITHDRAWN

**(1117)** WITHDRAWN

**(1118)** Perioperative Extracorporeal Membrane Oxygenation-Based Protocol for Acute Pulmonary Embolectomy: Technique and Preliminary Results; __ F. Ius1, C. Fegbeutel1, C. Kühn1, I. Tudorache1, G. Warnecke1, M. Roumieh1, N. Koigeldiyev1, K. Olsson2, M. Hoeper2, A. Haverich1, S. Cebotari1. 1 _Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany,_ 2 _Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany_

**(1119)** Meticulous Closure of Collateral Blood Flow in the Perihilar Mediastinal Pleura Decreases Bleeding and Surgical Mortality in Lung Transplant Recipients with Pulmonary Hypertension; __ K. Hashimoto1, S. Sugimoto1, K. Imanishi1, T. Kurosaki2, K. Miyoshi1, S. Otani2, M. Yamane1, T. Oto2. 1 _Department of General Thoracic Surgery, Okayama University Hospital, Okyama, Japan,_ 2 _Department of Organ Transplant Center, Okayama University Hospital, Okyama, Japan_

## Pharmacy & Pharmacology

(Coronado Foyer)

**Poster Discussants:** Christine Aquilante, PharmD (USA), Kyle Dawson, PharmD, BCPS (USA), Patricia Ging, PharmD (Ireland), Walter Uber, PharmD (USA)

**(1120)** Safety and Efficacy of Four Factor Prothrombin Complex Concentrate for the Reversal of Warfarin in LVAD Patients Prior to Heart Transplantation; __ L. To, A. Jantz, L. Hencken, C. William, H. Nemeh. _Henry Ford Hospital, Sterling Heights, MI_

**(1121)** Reduced Dose 4-Factor Prothrombin Complex Concentrate Prior to Heart Transplant in Patients with Ventricular Assist Devices; __ I. Lam1, A. A. Feist1, K. Derry1, J. Lane1, M. Mariski1, V. Pretorius2. 1 _Pharmacy, UC San Diego Health, San Diego, CA,_ 2 _Surgery, UC San Diego Health, San Diego, CA_

**(1122)** Risk Factors for Leukopenia with Valganciclovir Prophylaxis in CMV High Risk Cardiothoracic Transplant Recipients; __ A. J. Brueckner, C. T. Doligalski, A. T. Logan. _Pharmacy, Tampa General Hospital, Tampa, FL_

**(1123)** Still Inferior? Risks of Azathioprine in Tacrolimus Based Regimens for Heart Transplant Recipients; __ J. P. Casale, A. T. Logan, C. T. Doligalski. _Tampa General Hospital, Lutz, FL_

**(1124)** Vaccinating Lung Transplant Candidates; __ M. G. Cortez, L. Potter. _Department of Pharmacy, The University of Chicago Medicine, Chicago, IL_

**(1125)** Penicillium Species: Prevalence and Impact on Clinical Outcomes Following Lung Transplantation; __ N. Hudec1, C. King2, M. Fregoso2, A. Brown2, O. A. Shlobin2, A. B. Cochrane2. 1 _Butler University, Indianapolis, IN,_ 2 _Inova Fairfax, Falls Church, VA_

**(1126)** Pain Pathway in Lung Transplantation Is Associated with Excellent Peri-Operative Outcomes: A Case Series; __ D. B. Berkheim1, T. A. Nicholas2, M. J. Moulton1, H. M. Strah3, A. Siddique1. 1 _Surgery Division of Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE,_ 2 _Anesthesiology, University of Nebraska Medical Center, Omaha, NE,_ 3 _Internal Medicine Division of Pulmonary, Critical Care, Sleep & Allergy, University of Nebraska Medical Center, Omaha, NE_

**(1127)** Intra-Patient Variability of Tacrolimus Levels and Lung Allograft Outcomes: A Single Centre Experience; __ L. Diannelidou-Stamelou1, L. Spurr1, N. Leaver1, J. Smith1, A. Simon1, M. Carby1, A. Reed1, L. Wei2, H. Lyster1. 1 _Royal Brompton & Harefield NHS Foundation Trust, London, United Kingdom, _2 _Department of Practice and Policy, University College London, London, United Kingdom_

**(1128)** Prevalence of Venous Thromboembolic Events in ILD Lung Transplant Patients Treated with Sirolimus; __ G. Waldman, M. Mariski, A. Feist, L. Awdishu, K. Afshar, G. Yung. _University of California San Diego Health, San Diego, CA_

**(1129)** Rabbit Antithymocyte Globulin for the Treatment of Chronic Lung Allograft Dysfunction; __ S. January1, K. Fester1, K. Bain1, R. Hachem2. 1 _Pharmacy, Barnes-Jewish Hospital, St Louis, MO,_ 2 _Pulmonary and Critical Care, Washington University in St. Louis, St Louis, MO_

**(1130)** Implementation of Pre-Transplant Pharmacist Evaluations at a Thoracic Transplant Center; __ M. Mariski Jr1, A. Feist1, K. Afshar2, I. Gutman1, E. Adler3, G. Yung2. 1 _Pharmacy, UC San Diego Health, San Diego, CA,_ 2 _Pulmonology, UC San Diego Health, San Diego, CA,_ 3 _Cardiology, UC San Diego Health, San Diego, CA_

**(1131)** Utilization of a Multidisciplinary Approach for Inpatient Anticoagulation Management in Left Ventricular Assist Device Recipients; __ N. Siddiqi1, A. Luke2, S. Watts3, U. P. Jorde2, O. Saeed2, D. B. Sims2, J. Shin2, S. R. Patel2, S. Murthy2, S. Forest3, D. J. Goldstein3. 1 _Department of Pharmacy, Montefiore Medical Center, Bronx, NY,_ 2 _Department of Medicine (Cardiology), Montefiore Medical Center, Bronx, NY,_ 3 _Department of Cardiothoracic Surgery, Montefiore Medical Center, Bronx, NY_

**(1132)** Bivalirudin for Suspected Pump Thrombosis in Patients with Left Ventricular Assist Devices: A Single-Center Experience; __ P. A. Weeks1, A. Sieg2, I. Rajapreyar3, S. Nathan4. 1 _Pharmacy, Memorial Hermann - Texas Medical Center, Houston, TX,_ 2 _University of Kentucky College of Pharmacy, Lexington, KY,_ 3 _The University of Alabama at Birmingham, Birmingham, AL,_ 4 _Center for Advanced Heart Failure, University of Texas Health Science Center, Houston, TX_

# Poster Session 3

Friday, April 07, 2017

5:45 PM - 6:45 PM

NOTE: Poster presenters and discussants will be present during the evening poster viewing session from 5:45 PM – 6:45 PM.

## Basic Science & Translational Research

(Harbor Foyer)

**Poster Discussants:** Sharon Chih, MD (Canada), Tobias Deuse, MD, PhD (USA), Howard Eisen, MD (USA), Stephan Ensminger, MD, DPhil (Germany), Andrew E Gelman, PhD (USA), Tereza Martinu, MD, PhD (Canada), Erin Lowery, MD (USA), Johan Nilsson, MD, PhD (Sweden), Meinoshin Okumura, MD (Japan), Simon Pecha, MD (Germany), William E Stansfield, MD (Canada), Stijn E Verleden, PhD (Belgium), Christopher H Wigfield, MD, FRCS (USA)

**(1135)** Tyrosine Kinase Inhibitor Nintedanib Reduces Development of Transplant Vasculopathy in a Murine Aortic Transplantation Model; __ A. Gocht1, S. M. Ensminger2, J. Distler3, B. Spriewald3, M. Ramsperger-Gleixner1, M. Weyand1, C. Heim1. 1 _University of Erlangen Department of Cardiac Surgery, Erlangen, Germany,_ 2 _HDZ NRW, Bad Oeynhausen, Germany,_ 3 _University of Erlangen, Erlangen, Germany_

**(1136)** WITHDRAWN

**(1137)** Advancing the Science of Hemocompatibility: Oncostatin M, a Novel Biomarker for Blood Pump Induced Neutrophil Activation; __ J. Long1, K. Nelson1, J. Mayes1, D. Schmidtke2, T. Snyder1, Z. Liu3, R. McEver3, H. Setiadi1. 1 _Advanced Cardiac Care, INTEGRIS Baptist Medical Center, Oklahoma City, OK,_ 2 _The University of Texas at Dallas, Richardson, TX,_ 3 _Oklahoma Medical Research Foundation, Oklahoma City, OK_

**(1138)** Pulmonary Hypertension: Macrophage Infiltration Corelates with Right Ventricular Remodeling in an Experimental Model of Pulmonary Hypertension; __ J. Guihaire1, T. Deuse2, D. Wang1, E. Fadel3, H. Reichenspurner4, R. C. Robbins5, S. Schrepfer1. 1 _Transplant and Stem Cell Immunobiology Lab (TSI), Hamburg, Germany,_ 2 _CT Surgery, UCSF, Hamburg, CA,_ 3 _Thoracic and Vascular Surgery and Heart-Lung Transplantation, Paris, France,_ 4 _Cardiovascular Surgery, UHZ, Hamburg, Germany,_ 5 _CT Surgery, Stanford University, Stanford, CA_

**(1139)** H-Y-Incompatible Stem Cell Transplantation Causes Rejection of Nucleus Matched Cells; __ X. Hu1, S. T. Kueppers2, T. Deuse1, M. Alawi3, D. Wang1, H. Reichenspurner4, S. Schrepfer1. 1 _Surgery, TSI Lab, UCSF, San Francisco, CA,_ 2 _Surgery, TSI Lab, UHZ, Hamburg, Germany,_ 3 _Heinrich Pette, UKE, Hamburg, Germany,_ 4 _Cardiovascular Surgery, UHZ, Hamburg, Germany_

**(1140)** N-acetylcysteine Potentiates the Protective Effects of α-1-Antitrypsin in a Mouse Model of Orthotopic Lung Transplantation; __ K. Patel1, Q. Cheng2, L. Rucker2, G. Bazzle2, S. Nadig1, C. Atkinson1. 1 _Departments of Microbiology and Immunology, and Surgery, Medical University of South Carolina, Charleston, SC,_ 2 _Departments of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC_

**(1141)** Janus Kinase Inhibitor Tofacitinib Moderates De Novo Donor Specific Antibody Production in a Mouse Model of HLA-A2 Sensitization; __ N. Chai, I. Kim, S. Jordan, A. Klein, G. D. Wu. _Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA_

**(1142)** Use of Exosome for Alloantibody Suppression: A Study in a Mouse Model of HLA-A2 Sensitization; __ I. Kim1, G. De Couto2, N. Chai3, G. D. Wu3, A. S. Klein3, S. Jordan3. 1 _Comprehensive Transplant Center/Surgery, Cedars-Sinai Medical Center, Los Angeles, CA,_ 2 _Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA,_ 3 _Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA_

**(1143)** Novel Therapeutic Strategies for Neutropenia in Transplantation; __ D. Sykes, M. Callahan, M. K. Mansour. _Massachusetts General Hospital, Boston, MA_

**(1144)** Suppression of Recall Alloantibody Responses by CTLA4Ig Is Associated with Reduction of CD138+ Plasma Cells in a Mouse Model of Allosensitization; __ G. D. Wu, I. Kim, N. Chai, S. Jordan, A. Klein. _Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA_

**(1145)** Mitochondria Energetics Is Significantly Altered During Acute Cellular Rejection in a Rat Transplantation Model; __ S. Agbor-Enoh1, H. Chen2, K. J. Deans2, P. C. Minneci2, M. S. Abu-Asab3, M. Tsokos3, C. Y. Demirkale4, J. J. Barb4, P. J. Munson4, R. L. Danner2, H. A. Valantine1, M. A. Solomon2. 1 _Laboratory of Transplant Genomics, Nat'l Inst. of Health, Bethesda, MD,_ 2 _Clinical Center, Nat'l Inst. of Health, Bethesda, MD,_ 3 _Section of Histopathology, National Eye Institute, Nat'l Inst. of Health, Bethesda, MD,_ 4 _Mathematical and Statistical Computing Laboratory, Center for Information Technology, Nat'l Inst. of Health, Bethesda, MD_

**(1146)** WITHDRAWN

**(1147)** Pyroptosis of Passenger Leukocytes Negatively Impacts the Quality of Lung Grafts During Ex Vivo Lung Perfusion; __ K. Noda, S. Tane, A. J. Hayanga, J. D'Cunha, J. D. Luketich, N. Shigemura. _Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA_

**(1148)** Inhibition of Regulated Necrosis by Necrostatin-1 Attenuates RIPK-1 Mediated Ischemia-Reperfusion Lung Injury After Lung Transplantation; __ T. Kanou, A. Ohsumi, H. Kim, M. Chen, Z. Guan, X. Bai, D. Hwang, M. Cypel, S. Keshavjee, M. Liu. _Latner Thoracic Surgery Research Laboratories, Toronto General Research Institute, Toronto, ON, Canada_

**(1149)** Effect of Interleukin 10 Gene-Modified Human Umbilical Cord Mesenchymal Stem Cells on Lung Ischemia Reperfusion Injury in a Rat Lung Transplantation Model; __ W. Mao, J. Chen. _Department of Lung Transplant Center, Key Laboratory of Human Organ Transplant in Jiangsu Province, Nanjing Medical University Affiliated Wuxi People's Hospital, Wuxi, China_

**(1150)** Static Cold Storage Induces Metabolic Alterations and Autophagy in Models of Cardiac Transplantation; __ D. T. Tran1, C. Dong2, A. Alawieh1, G. Beeson3, C. Atkinson4, S. N. Nadig5. 1 _Microbiology & Immunology, Medical University of South Carolina, Charleston, SC, _2 _College of Medicine, Medical University of South Carolina, Charleston, SC,_ 3 _Drug Discovery & Biomedical Sciences, Medical University of South Carolina, Charleston, SC, _4 _Microbiology & Immunology; Surgery, Division of Transplant Surgery, Medical University of South Carolina, Charleston, SC, _5 _Surgery, Division of Transplant Surgery, Medical University of South Carolina, Charleston, SC_

**(1151)** Optimal Perfusate Oxygenation During Ex Vivo Lung Perfusion Can Promote Alveolar Proliferation in Lung Grafts; __ K. Noda, S. Tane, A. J. Hayanga, J. D'Cunha, J. D. Luketich, N. Shigemura. _Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA_

**(1152)** Warm Retrograde Perfusion Can Remove More Fat from Lung Grafts with Fat Embolism in a Porcine Donor Model; __ M. Irie1, S. Otani2, T. Kurosaki2, Y. Shikatani1, K. Mesaki1, K. Hashimoto1, S. Tanaka1, K. Miyahara1, T. Ohki1, K. Miyoshi1, S. Sugimoto1, M. Yamane1, S. Miyoshi1, T. Oto2. 1 _Department of Thoracic Surgery, Okayama University Hospital, Okayama, Japan,_ 2 _Department of Organ Transplant Center, Okayama University Hospital, Okayama, Japan_

**(1153)** Identifying Cell Type-Specific or Common Biomarkers for Ischemia-Reperfusion Induced Injury in Lung Transplantation; __ A. K. Wong1, Y. Lu2, R. Zamel2, M. Liu2. 1 _Institute of Medical Science, University of Toronto, Toronto, ON, Canada,_ 2 _Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, Toronto, ON, Canada_

**(1154)** DUAL Ex Vivo Lung Perfusion Techniques Can Contribute to Better Posttransplant Outcomes Through Reconditioning Hypoxic Cells in Lung Grafts; __ K. Noda, S. Tane, A. J. Hayanga, J. D'Cunha, J. D. Luketich, N. Shigemura. _Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA_

**(1155)** ST266 Improves Oxygenation and Reduces Tissue Injury in an In-Situ Rat Left Lung Ischemia-Reperfusion Model; __ C. F. Evans1, X. Wang2, X. Liu1, R. Mishra1, V. Mishra3, S. Rahimpour1, A. Zeevi4, R. Banas5, S. M. Pham1. 1 _Surgery, University of Maryland, Baltimore, MD,_ 2 _Cardiac Surgery, Shanxi Dayi Hospital, Shanxi Academy of Medical Sciences, Baltimore, China,_ 3 _University of Maryland, Baltimore, MD,_ 4 _Pathology, University of Pittsburgh, Pittsburgh, PA,_ 5 _Noveome Biotherapeutics, Inc., Pittsburgh, PA_

**(1156)** Protective Effect of Anesthetic Preconditioning During Ex Vivo Lung Perfusion in a Rat Lung Transplantation Model; __ A. Ohsumi1, K. Marseu2, P. Slinger2, K. McRae2, T. Waddell1, M. Liu1, S. Keshavjee1, M. Cypel1. 1 _Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, Toronto, ON, Canada,_ 2 _Department of Anesthesiology, Toronto General Hospital, University of Toronto, Toronto, ON, Canada_

**(1157)** Microvascular Integrity Can Be Preserved by Anti-Platelet Therapy and in Combination with mTOR Inhibitor; __ C. Heim1, M. A. Khan2, B. Motsch1, A. Gocht1, M. Ramsperger-Gleixner1, T. Stamminger3, M. R. Nicolls2, M. Weyand1, S. M. Ensminger4. 1 _University of Erlangen Department of Cardiac Surgery, Erlangen, Germany,_ 2 _Stanford University, Palo Alto, CA,_ 3 _University of Erlangen, Erlangen, Germany,_ 4 _HDZ NRW, Bad Oeynhausen, Germany_

**(1158)** Diversity of Circulating Leukocyte Populations in Rat and Human Ex Vivo Lung Perfusion Circuits; __ D. Putman, A. Ohsumi, Y. Watanabe, T. Kanou, M. Chen, K. Boonstra, T. Martinu, S. Keshavjee, M. Cypel, S. C. Juvet. _Latner Thoracic Surgery Laboratories, University Health Network, Toronto, ON, Canada_

**(1159)** Impairment of the Protective PI3K/Akt Signaling Pathway in Transplanted Type-1 Diabetic Hearts Increases Post-Transplant Myocardial Injury; __ S. Korkmaz-Icöz1, S. Li1, S. Loganathan1, T. Radovits2, M. Ruppert1, P. Brlecic1, T. Fleming3, M. Brune3, P. Most4, M. Karck1, G. Szabó1. 1 _Cardiac Surgery, University of Heidelberg, Heidelberg, Germany,_ 2 _2Heart and Vascular Center, Semmelweis University, Budapest, Hungary,_ 3 _Medicine I and Clinical Chemistry, University of Heidelberg, Heidelberg, Germany,_ 4 _Molecular and Translational Cardiology, Department of Internal Medicine III, University of Heidelberg, Heidelberg, Germany_

**(1160)** Bronchial Artery Sparing Lung Preservation: Is It Feasible?; __ S. Tane, K. Noda, A. J. Hayanga, J. D'Cunha, J. D. Luketich, N. Shigemura. _Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA_

**(1161)** Nitrite Improves Mitochondrial Dysfunction Induced by Hypoxia/Reoxygenation in Lung Epithelial Cells: Implications for Ischemia-Reperfusion (I/R) Injury in Lung Transplantation ; __ A. Kumar, C. Corey, S. Shiva, M. T. Gladwin, J. D'Cunha. _University of Pittsburgh Medical Center, Pittsburgh, PA_

**(1162)** Augmentation of UW Solution with a Gap and Tight Junction Stabilizing Peptide, αCT1, Ameliorates Ischemia Reperfusion Injury, Facilitates Prolonged Graft Storage, and Protects Against the Development of Allograft Vasculopathy; __ K. Patel1, Q. Cheng1, R. Finnegan2, Z. Ballish2, L. Rucker2, S. Nadig1, C. Atkinson1. 1 _Departments of Microbiology and Immunology, and Surgery, Medical University of South Carolina, Charleston, SC,_ 2 _Departments of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC_

**(1163)** Continuous Hypothermic Perfusion of Old Donor Heart with a Preservation Solution Supplemented with Mesenchymal Stem Cell Conditioned Medium Improves Functional Graft Recovery During Prolonged Ischemic Time; __ S. Li1, S. Korkmaz1, M. Ruppert1, T. Radovits2, K. Li1, X. Sun1, P. Brlecic1, M. Karck1, G. Szabó1. 1 _Cardiac Surgery, University of Heidelberg, Heidelberg, Germany,_ 2 _Heart and Vascular Center, Semmelweis University, Budapest, Hungary_

**(1164)** Preservation Solution Affects the Immunological Milieu in Lung Transplantation and Alters the Inflammatory Balance; __ M. Seyda1, R. Bellmas-Sanz1, B. Wiegmann2, C. A. Neudoerfl1, A. Haverich2, C. S. Falk1, G. Warnecke2. 1 _Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany,_ 2 _Department for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany_

**(1165)** Involvement of Interleukin-17 During Acute and Chronic Allograft Rejection in Two Orthotopic Lung Transplantation Models; __ F. Calabrese1, F. Lunardi1, S. E. Vuljan1, M. Vadori2, D. Zampieri1, N. Nannini3, E. Cozzi3, F. Rea1. 1 _University of Padova, Padova, Italy,_ 2 _CORIT, Padova, Italy,_ 3 _Padova University Hospital, Padova, Italy_

**(1166)** Can Dantrolene Protect the Donor Heart Against Ischaemia-Reperfusion Injury?; __ J. E. Villanueva1, L. Gao1, H. C. Chew1, M. Hicks2, A. Doyle1, M. Qiu3, P. S. Macdonald4, A. Jabbour4. 1 _Transplant Laboratory, Victor Chang Cardiac Research Institute, Darlinghurst, Australia,_ 2 _Clinical Pharmacology and Toxicology, St Vincent's Hospital, Darlinghurst, Australia,_ 3 _SydPath Anatomical Pathology, St Vincent's Hospital, Darlinghurst, Australia,_ 4 _Heart and Lung Transplant Unit, St Vincent's Hospital, Darlinghurst, Australia_

**(1167)** Using a Cell Culture Model to Optimize Lung Preservation Solutions: Effects of Buffer and Nutrients; __ L. Jing, Z. Guan, S. Moodley, M. Zhao, M. Cypel, S. Keshavjee, M. Liu. _Latner Thoracic Surgery Research Laboratories, Toronto General Hospital Research Institute, University Health Network, University of Toronto, Toronto, ON, Canada_

**(1168)** ST266 Attenuates Acute Elastase-Induced Lung Emphysema in Mice; __ S. Rahimpour1, X. Liu1, X. Wang1, R. Banas2, C. Miller3, A. Zeevi4, S. M. Pham1. 1 _Surgery, University of Maryland, Baltimore, MD,_ 2 _Noveom Biotherapeutics, Pittsburgh, PA,_ 3 _Noveome Biotherapeutics, Pittsburgh, PA,_ 4 _University of Pittsbutgh, Pittsburgh, PA_

**(1169)** Paradoxical Mechano-Energetic Costs of Acute Mechanical Intra-Ventricular Unloading: A Key to Understand Myocardial Recovery with Left-Ventricular Mechanical Support?; __ S. Bennett1, C. L. del Rio2, J. Noel-Morgan3, E. Geist2, Y. Ueyama2, E. Ferris2, B. Youngblood2, P. I. McConnell3. 1 _The Ohio State University, Columbus, OH,_ 2 _QTest Labs, Dublin, OH,_ 3 _Nationwide Children's Hospital, Columbus, OH_

**(1170)** WITHDRAWN

**(1171)** Induction and Release of Exosomes Play a Significant Role in the Rejection of Syngeneic Murine Cardiac Grafts Following Administration of Antibodies to Cardiac Myosin; __ M. Sharma1, W. Liu2, M. Gunasekaran2, T. Mohanakumar2. 1 _St. Joseph's Hospital & Medical Center, Phoenix, AZ, _2 _St. Joseph's, Phoenix, AZ_

**(1172)** Beneficial Pleiotropic Effects of Multilineage-Differentiating Stress Enduring Cells on Acute Lung Ischemia-Reperfusion Injury; __ H. Yabuki1, S. Wakao2, Y. Kushida2, M. Dezawa2, Y. Okada1. 1 _Thorocic Surgery, Institution of Development, Aging and Cancer, Tohoku University, Sendai, Japan,_ 2 _Stem Cell Biology and Histology, Tohoku University Graduate School of Medicine, Sendai, Japan_

**(1173)** Cardio-Supportive Activity of Human Blood Monocytes in Human Engineered Heart Muscle; __ B. Fujita1, M. Tiburcy1, F. Bremmer2, S. Ensminger3, W. Zimmermann1. 1 _Institute of Pharmacology and Toxicology, University Medical Center Göttingen, Göttingen, Germany,_ 2 _Institute of Pathology, University Medical Center Göttingen, Göttingen, Germany,_ 3 _Thoracic and Cardiovascular Surgery, Heart and Diabetes Center NRW, Ruhr-Unviersity Bochum, Bad Oeynhausen, Germany_

**(1174)** Novel Method of Creating Three-Dimensional Myocardial Sheet Using Heart Scaffold and Isolated Cardiomyocytes; __ M. Kasai, H. Yagi, K. Okamoto, Y. Kitagawa, H. Shimizu. _Keio University, Tokyo, Japan_

**(1175)** Cardiomyocytological Phosphorylation Alterations in Mechanical Unloaded Hypertrophic and Failing Hearts; __ A. Schaefer1, Y. Schneeberger1, J. Stenzig2, A. P. Schwoerer2, T. Eschenhagen2, H. Ehmke2, H. Reichenspurner1, F. Cuello2. 1 _University Heart Center Hamburg, Hamburg, Germany,_ 2 _University Medical Center Eppendorf, Hamburg, Germany_

**(1176)** Non-Nucleosidic DNA Methyl Transferase Inhibition Attenuates Pressure Overload Induced Cardiac Hypertrophy in Rats; __ Y. Schneeberger1, J. Stenzig2, A. Löser2, A. Schaefer1, E. Wong3, W. Tan3, H. Reichenspurner1, R. Foo3, T. Eschenhagen2. 1 _University Heart Center Hamburg, Hamburg, Germany,_ 2 _University Medical Center Eppendorf, Hamburg, Germany,_ 3 _Genome Institute of SIngapore, Singapore, Singapore_

**(1177)** Role of Club Cells in the Development of Obliterative Bronchiolitis in Murine Transplanted Lungs; __ C. Konoeda, Z. Guan, P. Duchesneau, T. Watanabe, S. Juvet, M. Liu, T. Martinu, S. Keshavjee. _Latner Thoracic Surgery Research Laboratories, Toronto General Hospital, Toronto, ON, Canada_

**(1178)** The Ubiquitin Proteasome System as Potential Therapeutic Target in Dilated and Ischemic Cardiomyopathy; __ F. Emrich1, Y. D. Barac2, S. Steinbach1, K. Kellermann1, M. T. Dieterlen1, S. Lehmann1, T. Noack1, K. Penov3, D. Aravot2, A. Ciechanover4, F. W. Mohr1, J. Garbade1. 1 _Dep. of Cardiac Surgery, University of Leipzig, Heartcenter, Leipzig, Germany,_ 2 _The Cardiothoracic Surgery Department, Rabin Medical Center, Haifa, Israel,_ 3 _Dep. of Cardiothoracic Surgery, Stanford University, Stanford, CA,_ 4 _Tumor and Vascular Biology Research Center, Technion - Israel Institute of Technology, Haifa, Israel_

**(1179)** Donor Endothelial Inflammation and Recipient Leukocytes Contribute Independently to Primary Graft Dysfunction in Lung Transplant Recipients - Insights from a Humanized Mouse Model; __ A. Knoefel1, T. Siemeni1, N. Madrahimov1, W. Sommer1, M. Avsar1, F. Ius1, L. Pauksch1, K. Jansson1, J. Salman1, I. Tudorache1, C. Kühn1, A. Haverich1, C. S. Falk2, G. Warnecke1. 1 _HTTG, MHH, Hannover, Germany,_ 2 _Transplant Immunology, MHH, Hannover, Germany_

**(1180)** Evidence of Endothelial to Mesenchymal Transition (EndMT) in the Clinically Non-Failing Left Ventricles (CNFLV) of End Stage Right Ventricular Pressure Overload Patients; __ A. S. Cruz-Solbes, K. Youker, J. Amione-Guerra, J. D. Estep, B. H. Trachtenberg, A. Guha, G. Torre-Amione, A. Bhimaraj. _Methodist DeBakey Heart Center, Houston Methodist Hospital, Houston, TX_

**(1181)** Mitochondrial Dysfunction in Heart Failure: Similar Patterns in Rats and Humans ; __ G. Faerber, E. Heyne, M. Schwarzer, H. Kirov, T. Doenst. _Department of Cardiothoracic Surgery, University Hospital Jena, Jena, Germany_

**(1182)** Senescence Gene Signature of the Transplanted Heart; __ R. Araujo-Gutierrez, C. Uribe, K. A. Youker, M. H. Park, J. D. Estep, A. Guha, B. H. Trachtenberg, G. Torre-Amione, A. Bhimaraj. _DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, TX_

**(1183)** Investigation of Watershed Areas During Femoro-Femoral Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO) Using a Mock Loop Circuit; __ C. Cheong1, A. Xie1, H. Chew2, M. Shah1, S. Shehab3, P. MacDonald2, H. Buscher4, K. Dhital5. 1 _Faculty of Medicine, University of New South Wales, Kensington, Australia,_ 2 _Victor Chang Cardiac Research Institute, Darlinghurst, Australia,_ 3 _Department of Cardiology, St Vincent's Hospital, Darlinghurst, Australia,_ 4 _Intensive Care Unit, St Vincent's Hospital, Darlinghurst, Australia,_ 5 _Department of Cardiothoracic Surgery, St Vincent's Hospital, Darlinghurst, Australia_

**(1184)** In Vitro Hypoxia Pre-Conditioning of Stromal Vascular Fraction Cell-Based Constructs for Chronical Heart Ischemia Treatment; __ M. Mytsyk1, G. Cerino2, M. R. Grapow1, M. G. Muraro2, F. S. Eckstein1, A. Marsano2. 1 _Cardiac Surgery, University Hospital of Basel, Basel, Switzerland,_ 2 _Department of Biomedicine, University of Basel, Basel, Switzerland_

**(1185)** The "Giraffe Paradox": What Humans Can Learn from Giraffe in Heart Failure; __ D. Wang1, T. Deuse1, K. Ameri2, M. Stubbendorff3, H. Reichenspurner4, H. Schoon5, T. Theuss5, D. R. Cavener6, S. Schrepfer1. 1 _Surgery, TSI Lab, UCSF, San Francisco, CA,_ 2 _of Pediatrics/Biomedical Sciences, UCSF, San Francisco, CA,_ 3 _Cardiovascular Surgery, TSI Lab, UHZ, Hamburg, Germany,_ 4 _Cardiovascular Surgery, UHZ, Hamburg, Germany,_ 5 _Veterinary, Pathology University Leipzig, Leipzig, Germany,_ 6 _Genomis and Bioinformatics, University Pennsylvania, Pennsylvania, PA_

## Heart Transplantation

(Coronado Foyer)

**Poster Discussants:** Jason A Gluck, DO (USA), Feras Khaliel, MD, PhD (Saudi Arabia), Mehmet K Kirali, MD (Turkey), Maria M Mountis, DO (USA), Matthias Peltz, MD (USA), Ajay V Srivastava, MD (USA), John y Um, MD (USA), Andreas Zuckermann, MD (Austria)

**(1186)** Heart Transplantation in Prostate Cancer Patients; __ A. Iyengar1, N. Harati1, E. D. Adams1, C. Eisenring2, L. Reardon3, M. Deng3, A. Ardehali2, E. DePasquale3. 1 _David Geffen School of Medicine, University of California - Los Angeles, Los Angeles, CA,_ 2 _Department of Cardiac Surgery, University of California - Los Angeles, Los Angeles, CA,_ 3 _Department of Cardiology, University of California - Los Angeles, Los Angeles, CA_

**(1187)** Long-Distance Heart Procurement and One-Year Survival: A Retrospective Cohort Study; __ G. A. Braga, F. G. Marcondes-Braga, J. L. Xavier Junior, M. da Silva, S. Mangini, M. S. Ávila, G. C. de Souza, L. B. Seguro, I. W. Campos, M. Bonatto, M. Hoffmann, L. Escossia, R. H. Santos, F. A. Gaiotto, F. Bacal. _Núcleo de Transplante Cardíaco, Instituto do Coração, Sao Paulo, Brazil_

**(1188)** Outcomes of Combined vs. Sequential Heart-Kidney Transplant; __ M. Gallo, J. R. Trivedi, W. M. Whited, M. S. Slaughter. _Department of Cardiovascular and Thoracic Surgery, University of Lousville, Louisville, KY_

**(1189)** Transplant Volume Is Associated with Center Resource Availability and Graft Acceptance Threshold; __ C. W. Chen1, J. J. Chung1, A. C. Gaffey1, C. A. Bermudez1, L. R. Goldberg2, M. A. Acker1, P. Atluri1. 1 _Department of Surgery, University of Pennsylvania, Philadelphia, PA,_ 2 _Department of Medicine, University of Pennsylvania, Philadelphia, PA_

**(1190)** Warm Ischaemic Time for Donation After Circulatory Death Heart Donors - How Long Is Too Long?; __ M. B. Connellan, H. Chew, A. Iyer, C. Soto, P. Macdonald, K. Dhital. _Cardiothoraic and Transplant Surgery, St. Vincent 's Hosp, Sydney, Australia_

**(1191)** Transthyretin Amyloid Patients > 70 Years of Age Appear as Good Candidates for Heart Transplantation; __ J. Patel, M. Kittleson, R. Vescio, T. Aintablian, R. Sharoff, R. Levine, D. Geft, D. Chang, L. Czer, A. Trento, J. A. Kobashigawa. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(1192)** Informative and Uninformative Variables in the Scientific Registry of Transplant Recipients; __ E. M. Hsich1, L. Thuita2, D. McNamara3, J. G. Rogers4, J. Schold2, E. H. Blackstone5, H. Ishwaran6. 1 _Cardiology, Cleveland Clinic Foundation, Cleveland, OH,_ 2 _Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH,_ 3 _Cardiology, University of Pittsburgh Medical Center, Pittsburgh, PA,_ 4 _Cardiology, Duke University, Durham, NC,_ 5 _Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, OH,_ 6 _Department of Public Health Sciences, University of Miami, Miami, FL_

**(1193)** The Effect of Donor Anticonvulsant Use within 24 Hours of Aortic Cross-Clamp on 1-Year Recipient Survival; __ S. K. Lella1, K. Zolfaghari2, L. A. Copeland2, C. B. Sai-Sudhakar3, Y. Ravi3. 1 _College of Medicine, Texas A &M University, Dallas, TX, _2 _Center for Applied Health Research, Baylor Scott & White Health, Temple, TX, _3 _Cardiothoracic Surgery-Surgery, Baylor Scott & White Healthcare, Temple, TX_

**(1194)** Expanding the Donor Service Area to Greater Than 500 Miles Is Safe and Effective; __ H. Copeland1, D. Baran2, J. Copeland1, G. Katlaps1, B. Dharmaraj1. 1 _McGuire VA Medical Center, Richmond, VA,_ 2 _Newark Beth Israel Medical Ctr, Livingston, NJ_

**(1195)** To Accept or Not Accept, That Is the Question: Donor Heart Selection Process and Outcome of Discarded Organs Transplanted in Another Center; __ A. Z. Aliabadi-Zuckermann1, J. Goekler1, A. Kaider2, K. Uyanik-Uenal1, J. Riebandt1, R. Moayedifar1, E. Osorio1, T. Haberl1, G. Laufer1, J. Smits3, A. O. Zuckermann1. 1 _Cardiac Surgery, Medical University of Vienna, Vienna, Austria,_ 2 _Medical Statistics, Medical University of Vienna, Vienna, Austria,_ 3 _Eurotransplant Foundation, Leiden, Netherlands_

**(1196)** Donor Age Significantly Impacts Long Term Survival of Patients Undergoing Heart Transplantation; __ E. B. Lushaj, R. Dhingra, T. Kohmoto, S. Osaki, P. Tang, M. Johnson, L. Lozonschi. _University of Wisconsin, Madison, WI_

**(1197)** Towards a Cardiac Allocation Score: A Retrospective Calculation for 73 Patients from a German Transplant Center; __ S. Grundmann, S. Claes, M. Berchtold-Herz, Q. Zhou, G. Trummer, A. Zirlik, F. Beyersdorf, C. Bode. _University Heart Center Freiburg, Freiburg, Germany_

**(1198)** Heart Transplantation as an Option for End-Stage Chronic Chagas Heart Disease. A Public Hospital Experience; __ P. Avellana, A. Ini, D. Radlovachki, M. Ajzenszlos, J. Giorgini, M. Tibaudin, A. Rodriguez, A. Stewart Harris, L. Ahualli. _Hospital Cosme Argerich, Buenos Aires, Argentina_

**(1199)** Red Blood Cell Distribution Width Predicts Mortality After Heart Transplantation; __ A. Lechiancole, S. Sponga, G. Valdi, C. Nalli, V. Tursi, U. Livi. _Cardio-Thoracic Surgery, University Hospital of Udine, Udine, Italy_

**(1200)** Post-Operative Acute Renal Failure Adversely Impacts Long-Term Survival After Successful Heart Transplant: Analysis of a National Database; __ S. Deo1, S. E. Altarabsheh2, N. Sarabu3, S. Dunlay4, A. Kilic5, G. Fonarow6, S. J. Park1. 1 _Cardiac Surgery, University Hospitals, Cleveland, OH,_ 2 _Cardiac Surgery, Queen Alia Heart Insttute, Jordan, Jordan,_ 3 _Nephrology, University Hospitals, Cleveland, OH,_ 4 _Cardiology, Mayo Clinic, Rochester, MN,_ 5 _Cardiac Surgery, Wexner Heart Center, Ohio State University, Columbus, OH,_ 6 _Cardiology, Ronald Reagan Medical Center, University of California, Los Angeles, Los Angeles, CA_

**(1201)** Pregnancy After Heart Transplantation: A Well-Thought-Out Decision?; __ O. Dagher1, N. Laroussi2, B. Cantin3, M. Carrier1, R. Cecere4, E. Charbonneau3, S. De Denus1, N. Giannetti4, L. Leduc2, S. Levesque5, N. Poirier2, M. Raboisson2, M. White1, A. Ducharme1. 1 _Montreal's Heart Institute (MHI), Montreal, QC, Canada,_ 2 _Sainte-Justine's University Hospital, Montreal, QC, Canada,_ 3 _Institut Universitaire de Cardiologie et de Pneumologie de Québec, Quebec, QC, Canada,_ 4 _McGill University Health Centre, Montreal, QC, Canada,_ 5 _Montreal Health Innovations Coordinating Center (MHICC), Montreal, QC, Canada_

**(1202)** Risk of Early, Intermediate, and Late Rejection Following Heart Transplantation (HT): Trends Over the Past 25 Years and Relation to Changes in Medical Management; __ Y. Peled, M. Katz, M. Arad, Y. Kassif, Y. Shemesh, E. Asher, D. Elian, Y. Har-Zahav, N. Shlomo, D. Freimark, J. Lavee, I. Goldenberg. _Sheba Medical Center and Tel Aviv University, Tel Aviv, Israel_

**(1203)** Total Perpheral Resistance Does Not Increase During Orthostatic Challenge in Recently Heart Transplanted Patients; __ S. I. Nygaard1, G. Dohlen1, V. B. Wyller2. 1 _Oslo University Hospital, Oslo, Norway,_ 2 _Dept. of Paediatrics, Akershus University Hospital, Lørenskog, Norway, Lørenskog, Norway_

**(1204)** One Year Survival After Heart Transplantation: Chagasic x Non-Chagasic Patients; __ J. L. Xavier, F. G. Marcondes-Braga, G. A. Braga, M. Silva, G. C. Souza, S. Mangini, M. S. Ávila, L. B. Seguro, M. D. Tonin, L. L. Da Escossia, L. L. Da Escossia, M. G. Bonatto, J. L. De Melo, F. A. Gaiotto, F. Bacal. _Heart Transplantation, Heart Institute, São Paulo University, Brasil, São Paulo, Brazil_

**(1205)** Does Stroke in the Perioperative Post Cardiac Transplant Period Impact Survival?; __ N. Nair1, S. Yang2, E. Gongora3. 1 _Cardiology, Texas Tech Health Sciences Center, Lubbock, TX,_ 2 _Internal Medicine, Texas Tech Health Sciences Center, Lubbock, TX,_ 3 _Cardiothoracic Surgery, Memorial Cardiac and Vascular Institute, Hollywood, FL_

**(1206)** Heart Transplantation Bridged by Extracorporeal Life Support in the Adults: Experience from Samsung Medical Center in South Korea; __ J. Lee, Y. Cho. _Thoracic and Cardiovascular Surgery, Samsung Medical Center, Seoul, Korea, Republic of_

**(1207)** The Transmitral Peak Flow Velocity-Mitral Annular Diastolic Velocity Ratio (e/e') Does Not Predict Left Ventricular Filling Pressure Post Cardiac Transplant; __ A. Selim1, R. Zolty1, A. Burdorf1, J. Um2, A. Siddique2, M. Moulton2, B. Lowes1, E. Raichlin1. 1 _Cardiology, University of Nebraska Medical Center, Omaha, NE,_ 2 _Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE_

**(1208)** Does Type of Mechanical Circulatory Support Influence Stroke Risk in the Perioperative Post Transplant Period?; __ N. Nair1, S. Yang2, E. Gongora3. 1 _Cardiology, Texas Tech Health Sciences Center, Lubbock, TX,_ 2 _Internal Medicine, Texas Tech Health Sciences Center, Lubbock, TX,_ 3 _Cardiothoracic Surgery, Memorial Cardiac and Vascular Institute, Hollywood, FL_

**(1209)** American Population Derived Donor Score System Assessment in a Brazilian Heart Transplantation Cohort; __ L. L. Escossia, M. G. Bonatto, M. H. Tonin, S. Mangini, F. Marcondes-Braga, F. Bacal, M. S. Avila, I. Wosniak, L. Seguro, A. C. Dutra, A. R. de Paulo, J. L. Melo, F. Barone. _Heart Transplant - Incor, Incor - Medicine University of São Paulo, São Paulo, Brazil_

**(1210)** WITHDRAWN

**(1211)** Outcomes of US Patients with Marfans Syndrome Listed for Heart Transplantation; __ B. D. Kaufman1, S. E. Tierney1, D. Bernstein1, S. H. Chen1, J. Dykes1, S. A. Hollander1, D. H. Liang2, K. Maeda3, J. Priest1, O. Reinhartz3, D. N. Rosenthal1, C. Almond1. 1 _Pediatrics, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA,_ 2 _Medicine, Stanford University, School of Medicine, Palo Alto, CA,_ 3 _Cardiothoracic Surgery, Lucile Packard Children's Hospital, Stanford University, Palo Alto, CA_

**(1212)** Modified Bicaval Technique in Orthotopic Heart Transplantation: Comparison with Conventional Bicaval Technique; __ H. Kim1, S. Jung1, J. Kim2, T. Yun1, J. Lee1. 1 _Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, Seoul, Korea, Republic of,_ 2 _Department of Cardiology, Asan Medical Center, Seoul, Korea, Republic of_

**(1213)** Outcome of HVAD Bridged to Transplantation Patients After Heart Transplantation - A Single Center Experience; __ R. Moayedifar1, D. Zimpfer1, D. Wiedemann1, J. Riebandt1, K. Dimitrov1, T. Schlöglhofer2, T. Haberl1, A. Aliabadi1, E. Osorio1, K. Freystaetter1, K. Uyanik-Uenal1, G. Laufer1, A. Zuckermann1. 1 _Cardiac Surgery, Vienna General Hospital, Vienna, Austria,_ 2 _Center for Medical Physics and Biomedical Engineering, Vienna General Hospital, Vienna, Austria_

**(1214)** Excellent Outcomes After Heart Transplantation in Stable, Highly-Sensitized Heart Transplant Recipients Using a Wait and Match Strategy; __ J. Nativi, D. Hurst, G. Bullock, E. Bullock, J. Delgado, A. Pole, J. Stehlik, K. Afshar, S. Drakos, J. R. Doty, S. H. McKellar, R. Alharethi, O. Wever-Pinzon, K. Molina, J. Fang, A. Kfoury. _UTAH Cardiac Transplant Program, Salt Lake City, UT_

**(1215)** The Immediate Response in Markers of Inflammation and Angiogenesis During Exercise in Heart Transplant Recipients; __ M. Yardley1, T. Ueland2, P. Aukrust3, A. Michelsen2, E. Bjørkelund1, L. Gullestad1, K. Nytrøen1. 1 _Cardiology Department, OUS-HF Rikshospitalet, Oslo, Norway,_ 2 _Research Institute of Internal Medicine, OUS-HF Rikshospitalet, Oslo, Norway,_ 3 _Research Institute of Internal Medicine, Section of Clinical Immunology and Infectious Disease, OUS-HF Rikshospitalet, Oslo, Norway_

**(1216)** Alterations in Vascular Endothelial Growth Factors After Heart Transplantation; __ J. Lundgren1, S. Nielsen2, C. Scheele2, G. Rådegran1. 1 _Cardiology, Clinical Sciences, Lund University, Sweden,_ 2 _Centre of Inflammation and Metabolism, University of Copenhagen, Denmark_

**(1217)** Incidence, Causes, and Cost Analysis of Unplanned Hospital Readmissions After Heart Transplantation; __ E. B. Lushaj, T. Kohmoto, L. Lozonschi, S. Osaki, S. Ulschmid, S. Akhter. _University of Wisconsin, Madison, WI_

**(1218)** Analysis of Individual Gene Expression Levels Indicates the Impact of Physiological Functions on Gene Expression Profiling Scores; __ S. A. Hall1, S. Pinney2, J. Sninsky3, M. Machrus3, R. Woodward3, A. Kao4. 1 _Cardiology, Baylor University Medical Center, Dallas, TX,_ 2 _Cardiology, Mount Sinai Health System, New York, NY,_ 3 _CareDx, Brisbane, CA,_ 4 _Cardiology, St. Luke's Health System, Mid America Heart Institute, Kansas City, MO_

**(1219)** Association Between LVAD and Cardiac Allograft Injury Following Heart Transplantation as Assessed by Cell-Free DNA; __ M. E. Rodrigo1, S. Agbor-Enoh2, S. Gorham2, U. Fideli2, I. Tunc2, M. Jang2, Y. Yang2, K. Bhatti2, A. Marishta1, P. Shah3, S. Pham4, K. Shah5, S. Russell6, E. Feller7, S. S. Najjar1, H. Valantine2. 1 _Cardiology, Medstar Washington Hospital Center, Washington, DC,_ 2 _National Institutes of Health, Bethesda, MD,_ 3 _Cardiology, INOVA Fairfax, Falls Church, VA,_ 4 _University of Maryland, Baltimore, MD,_ 5 _Cardiology, Virginia Commonwealth University, Richmond, VA,_ 6 _Cardiology, Johns Hopkins Hospital, Baltimore, MD,_ 7 _Cardiology, University of Maryland, Baltimore, MD_

**(1220)** Impact of Insurance Status on Heart Transplant Graft Survival; __ P. C. Tang, X. Wang, G. E. Leverson, T. Kohmoto, S. Osaki, S. A. Akhter, R. Dhingra, M. R. Johnson, L. Lozonschi. _Surgery, Univeristy of Wisconsin Hospitals and Clinics, Madison, WI_

**(1221)** Incidence and Implications of Primary Graft Dysfunction in Heart Transplantation Using the ISHLT Consensus Criteria; __ C. A. Bermudez1, M. R. Molina1, L. R. Goldberg2, S. Chambers2, P. Atluri1, R. Forde-Mclean2, J. I. Gentile1, J. Wald2, E. Rame2, M. Jessup2, E. Y. Birati2, M. A. Acker1. 1 _Cardiovascular Surgery, Hospital of the University of Pennsylvannia, Philadelphia, PA,_ 2 _Heart Failure and Cardiac Transplant Program, Hospital of the University of Pennsylvannia, Philadelphia, PA_

**(1222)** A Pilot Evaluation of the Post-Operative Glasgow Transplant Score (Post-GTStm) for Heart Transplants; __ S. Avtaar Singh1, T. Vassalos2, F. Nolan3, J. Sharp4, A. M. Young5, N. Al-Attar6. 1 _Cardiothoracic Surgery, Golden Jubilee National Hospital, Glasgow, United Kingdom,_ 2 _Anaesthetics and Intensive Care, Golden Jubilee National Hospital, Glasgow, United Kingdom,_ 3 _Physiotherapy, Golden Jubilee National Hospital, Glasgow, United Kingdom,_ 4 _Clinical Psychology, Golden Jubilee National Hospital, Glasgow, United Kingdom,_ 5 _Dietetics and Nutrition, Golden Jubilee National Hospital, Glasgow, United Kingdom,_ 6 _Scottish National Adult Heart Failure Service, Golden Jubilee National Hospital, Glasgow, United Kingdom_

**(1223)** Successful One-Year Survival in Heart Transplant Recipients Requiring Extracorporeal Membrane Oxygenation for Primary Graft Dysfunction; __ N. Rajagopalan, D. R. Dennis, T. Mooney, T. Tribble, P. Tessmann, A. Shafii, M. E. Sekela. _University of Kentucky, Lexington, KY_

**(1224)** Vasoplegia in the Absence of Primary Graft Dysfunction Is Not Associated with Increased Mortality Following Cardiac Transplantation; __ F. S. Raza, G. V. Gonzalez-Stawinski, S. M. Joseph, G. Saracino, A. K. Jamil, J. Felius, S. A. Hall, A. E. Rafael, J. C. MacHannaford, A. S. Bindra, B. Lima. _Baylor University Medical Center, Dallas, TX_

**(1225)** Dose-Dependent Association Between Amiodarone and Primary Graft Dysfunction in Heart Transplantation; __ M. Wright1, K. Takeda1, C. Mauro2, D. Jennings1, P. Kurlansky1, J. Han1, L. Truby1, S. Stein1, V. Topkara1, A. R. Garan1, M. Yuzefpolskaya1, P. Colombo1, Y. Naka1, M. Farr1, H. Takayama1. 1 _Columbia University Medical Center, New York, NY,_ 2 _Columbia University, Mailman School of Public Health, New York, NY_

**(1226)** Primary Graft Dysfunction (PGD) After Heart Transplantation (HTx): Veno-Arterial ECMO as Bridge-to-Recovery?; __ U. Boeken1, A. Mehdiani1, B. Sowinski1, A. Schmidt1, H. Dalyanoglu1, R. Westenfeld2, P. Akhyari1, D. Saeed1, A. Lichtenberg1. 1 _Cardiovascular Surgery, University Hospital, Duesseldorf, Germany,_ 2 _Cardiology, University Hospital, Duesseldorf, Germany_

**(1227)** Reoperative Sternotomy Is Not Associated with Increased Rates of Primary Graft Dysfunction Following Cardiac Transplantation; __ B. Lima, S. Still, A. Shaikh, G. Saracino, A. K. Jamil, J. Felius, S. M. Joseph, S. A. Hall, A. E. Rafael, J. C. MacHannaford, G. V. Gonzalez-Stawinski. _Baylor University Medical Center, Dallas, TX_

**(1228)** Genomic Research Alliance for Transplantation (GRAfT) A Unique Cohort to Address Age, Sex and Race in Heart Transplants; __ U. S. Fideli1, S. Agbor-Enoh1, S. Gorham1, M. Jang1, Y. Yang1, K. Bhatti1, A. Marishta1, M. E. Rodrigo2, S. Najjar2, K. Shah3, S. Russell4, S. Pham5, E. Feller5, P. Shah6, H. Valantine1. 1 _National Heart, Lung and Blood Institute, National Institute of Health, Bethesda, MD,_ 2 _Medstar Washington Hospital Center, Washington, DC,_ 3 _Virginia Commonwealth University, Richmond, VA,_ 4 _Johns Hopkins University, Baltimore, MD,_ 5 _University of Maryland Medical Center, Baltimore, MD,_ 6 _Inova Heart and Vascular Institute, Falls Church, VA_

## Lung Transplantation

(Regatta Foyer)

**Poster Discussants:** Céline Bergeron, MD (Canada), Maria M Crespo, MD (USA), Marcelo Cypel, MD (Canada), Joshua Diamond, MD (USA), Daniel F Dilling, MD (USA), Maria C Gazzaneo, MD (USA), Matthew G Hartwig, MD (USA), Monique Malouf, FRACP (Australia), Richard N Pierson, III, MD (USA), Anna Reed, MBChB, MRCP, PhD (United Kingdom)

**(1229)** Eplet-Defined DQ Mismatches Predict for HLA Class II DSA Early Post-Lung Transplant: A Role in RAS?; __ D. Walton1, G. Snell2, L. Cantwell1, M. Paraskeva2, B. Levvey2, G. P. Westall2. 1 _Victorian Transplantation and Immunogenetics Service, Melbourne, Australia,_ 2 _Alfred Hospital, Melbourne, Australia_

**(1230)** The Implications of Immunophenotypic Analysis of Lung Allograft Biopsies; __ I. Timofte1, J. Heath2, J. Kim1, R. N. Pierson3, Z. Kon3, S. Pham3, A. Iacono4, A. Burke2. 1 _Pulmonary and Critical Care, UMMC, Baltimore, MD,_ 2 _Pathology, UMMC, Baltimore, MD,_ 3 _Surgery, UMMC, Baltimore, MD,_ 4 _UMMC, Baltimore, MD_

**(1231)** Plasmapheresis for the Treatment of Antibody-Mediated Rejection in Lung Transplant Recipients; __ M. Dordevic1, T. Sandhaus1, M. Leuze1, T. Steinke2, H. Kirov1, S. Rummler2, M. Steinert1, G. Faerber1, T. Doenst1. 1 _Department of Cardiothoracic Surgery, Friedrich Schiller University Jena, Jena, Germany,_ 2 _Institute of Transfusion Medicine, Friedrich Schiller University Jena, Jena, Germany_

**(1232)** Elevated Serum BAFF Levels Are Associated with an Increased Risk of Acute Rejection in Lung Recipients; __ L. Calahorra1, J. Cifrian2, E. Sarmiento1, I. Ezzahouri1, C. Bravo3, S. Lopez3, R. Laporta4, P. Ussetti4, A. Sole5, A. De Pablos6, M. Jaramillo1, J. Carbone1. 1 _Clinical Immunology, Hospital General Universitario Gregorio Marañon, Madrid, Spain,_ 2 _Pneumology, Hospital Marques de Valdecilla, Santander, Spain,_ 3 _Pneumology, Hospital Vall de Hebron, Barcelona, Spain,_ 4 _Pneumology, Hospital Puerta de Hierro, Madrid, Spain,_ 5 _Pneumology, Hospital La Fe., Valencia, Spain,_ 6 _Pneumology, Hospital Doce de Octubre, Madrid, Spain_

**(1233)** Coronary Disease and Lung Transplantation: Pulmonary Fibrosis Is a Cardiovascular Risk Factor?; __ F. Revuelta, L. A. Arvelo-Castro, M. Aguilar-Perez, N. Martos-Gisbert, S. Aguado-Ibañez, J. Carrillo, P. Ussetti. _Pulmonary Medicine, Universitary Hospital Puerta de Hierro, Madrid, Spain_

**(1234)** Decline in DLCO Precedes Decline in FEV1 or FVC After Lung Transplantation; __ C. M. Shaver, M. P. Steele, I. M. Robbins. _Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN_

**(1235)** WITHDRAWN

**(1236)** Post-Lung Transplant Survival After Venous Thromboembolism; __ B. C. Cahill1, T. G. Liou2, K. Peterson-Short3, T. Maughan3, W. Doidge3, B. Sirandas3, A. Carlson3, C. Truax3, L. Cotiguala3, S. Raman1, S. H. McKellar4, C. H. Selzman4. 1 _Division of Pulmonary Medicine and Lung Transplant Program, University of Utah School of Medicine, SLC, UT,_ 2 _Division of Pulmonary Medicine, University of Utah School of Medicine, SLC, UT,_ 3 _University of Utah Lung Transplant Program, SLC, UT,_ 4 _Division of Cardiothoracic Surgery and Lung Transplant Program, University of Utah School of Medicine, SLC, UT_

**(1237)** Which Extracorporeal Support Should We Use During Lung Transplantation? - Impact of CPB and ECMO on Peri-Operative Outcome; __ A. Slama1, V. Besa2, O. Abu Issa3, A. Koch3, N. Pizanis3, H. Teschler2, M. Kamler3, A. Clemens1. 1 _Dept. for Thoracic Surgery, Essen University Hospital, Essen, Germany,_ 2 _Dept. for Pneumology, Essen University Hospital, Essen, Germany,_ 3 _Dept. for Thoracic Organ Transplantation, Essen University Hospital, Essen, Germany_

**(1238)** Differences in De Novo Donor-Specific Anti-HLA Antibodies Between Living-Donor Lobar and Cadaveric Lung Transplantation; __ F. Gochi, T. F. Chen-Yoshikawa, T. Kondo, A. Ohsumi, K. Ohata, A. Takahagi, M. Saito, R. Okabe, H. Yamagishi, M. Hamaji, K. Hijiya, H. Motoyama, A. Aoyama, H. Date. _Department of Thoracic Surgery, Graduate School of Medicine, Kyoto University Hospital, Kyoto, Japan_

**(1239)** Characteristics and Outcome of Patients with Stroke After Lung Transplant Surgery in the Lung Allocation Score Era; __ A. Banga, M. Mohanka, S. Bollineni, J. Mullins, V. Kaza, F. Torres. _UT Southwestern Medical Center, Dallas, TX_

**(1240)** Value of Portable Perfusion Scans in the Immediate Post-Operative Period Following Lung Transplantation; __ R. L. Rosenblatt, A. Mock, P. Garcha, H. Huang, K. Ausloos, P. Aguilar, G. Schwartz, D. Mason. _Pulmonary, Simmons Transplant Institute, Dallas, TX_

**(1241)** CT Derived Estimates of Total Lung Volume in Transplant Candidates: Can We Do without Plethysmography?; __ C. Culshaw, H. Newton, R. Sutcliffe, J. Nuttall, A. Sharman, M. Al-Aloul. _Cardiothoracic Transplant Unit, University Hospital of South Manchester, Manchester, United Kingdom_

**(1242)** Short-Term Outcomes in Patients Taking Antifibrotic Agents for Idiopathic Pulmonary Fibrosis (IPF) After Lung Transplantation; __ A. Kafi1, J. Falk1, G. Chaux1, S. Ghandehari1, W. Chang2, D. Ramzy2. 1 _Pulmonary and Critical Care, Cedars Sinai Medical Center, Los Angeles, CA,_ 2 _Cardiothoracic Surgery, Cedars Sinai Medical Center, Los Angeles, CA_

**(1243)** Lung Transplantation from the ICU: Is It Justified?; __ T. C. Gan1, G. D. Nossent1, M. E. Erasmus2, A. Oude Lansink3, E. A. Verschuuren1, W. van der Bij1. 1 _Pulmonary Diseases, Tuberculosis and Lung Transplantation, University Medical Center Groningen, Groningen, Netherlands,_ 2 _Cardiothoracic Surgery, University Medical Center Groningen, Groningen, Netherlands,_ 3 _Intensive Care Medicine, University Medical Center Groningen, Groningen, Netherlands_

**(1244)** Systematic Review and Meta-Analysis of Death After Posttransplant Lymphoproliferative Disease in Lung Transplantation; __ C. A. Moore1, J. Cheng1, C. J. Iasella1, A. R. Glanville2, M. R. Morrell1, R. B. Smith1, J. Hayanga1, J. F. McDyer1, C. R. Ensor1. 1 _University of Pittsburgh, Pittsburgh, PA,_ 2 _St Vincent's Hospital, Sydney, Australia_

**(1245)** Accuracy of Ecocardiographic Assesment of Pulmonary Pressure in Lung Transplant Candidates; __ E. J. Wainstein1, H. M. Castro1, M. L. Orazi1, G. N. Svetliza1, J. Maritano Furcada1, J. A. Precerutti1, A. Da Lozzo2, E. Beveraggi2, D. E. Smith2. 1 _Internal Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina,_ 2 _Thoracic Surgery, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina_

**(1246)** Tracheostomy After Lung Transplantation Predicts Decreased Mid and Long Term Survival; __ S. J. Huddleston1, B. Roland2, K. Rudser2, U. Goswami3, S. J. Shumway1, M. Hertz3, G. Loor1, T. Rade3. 1 _Surgery, Division of Cardiothoracic Surgery, University of Minnesota, Minneapolis, MN,_ 2 _Biostatistical Design and Analysis Center, Division of Biostatistiscs, University of Minnesota School of Public Health, Minneapolis, MN,_ 3 _Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Minnesota, Minneapolis, MN_

**(1247)** Chronic Pain One to Five Years After Lung Transplantation - A Multicentre Study; __ A. Forsberg1, M. Claëson2, M. Lundmark3, M. Almgren3, A. Lennerling4. 1 _Institue of Health Sciences, Lund University, Lund, Sweden,_ 2 _The Department of Transplantation and Cardiology, Skåne University Hospital, Lund, Sweden,_ 3 _The Thoracic Intensive Care Unit, Skåne University Hospital, Lund, Sweden,_ 4 _The Transplant Unit, Sahlgrenska University Hospital, Gothenburg, Sweden_

**(1248)** Left Atrial Pressure Continuous Monitoring Improves Early Postoperative Outcomes After Double Lung Transplantation for Pulmonary Hypertension; __ O. Mercier, J. Lepavec, N. Langer, L. Lamrani, S. Mussot, D. Fabre, E. Lebret, F. Laverdure, G. Tachon, A. Patrascu, P. Viard, F. Stephan, P. G. Dartevelle, E. Fadel. _Centre Chirurgical Marie Lannelongue, Le Plessis Robinson, France_

**(1249)** WITHDRAWN

**(1250)** HFpEF Associated with Reduced Survival Following Lung Transplantation; __ J. P. Scott1, B. A. Boilson2, R. C. Daly3, M. E. Wylam4, S. G. Peters4, C. C. Kennedy4. 1 _Mayo Clinic, Rochester, MN,_ 2 _Cardiology, Mayo Clinic, Rochester, MN,_ 3 _Cardiac Surgery, Mayo Clinic, Rochester, MN,_ 4 _Pulmonary and Critical Care, Mayo Clinic, Rochester, MN_

**(1251)** Bronchial Complications After Living-Donor Lobar Lung Transplantation: Bronchial Stenoses in the Lobar to Segmental Bronchi Necessitating Earlier Intervention; __ S. Sugimoto1, T. Kurosaki2, K. Miyoshi1, S. Otani2, M. Yamane1, S. Miyoshi1, T. Oto2. 1 _General Thoracic Surgery, Okayama University Hospital, Okayama, Japan,_ 2 _Organ Transplant Center, Okayama University Hospital, Okayama, Japan_

**(1252)** Impact of Elevated Pulmonary Artery Pressure in Lung Recipients Transplanted for COPD; __ E. Poli1, P. Yerly2, T. Krueger3, M. Gonzalez3, H. F. Ris3, L. P. Nicod4, P. M. Soccal5, A. Brill6, M. Tamm7, J. D. Aubert8. 1 _Medical School, University of Lausanne, Lausanne, Switzerland,_ 2 _Cardiology, Lausanne University Hospital, Lausanne, Switzerland,_ 3 _Thoracic Surgery, Lausanne University Hospital, Lausanne, Switzerland,_ 4 _Pulmonary Medicine, Lausanne University Hospital, Lausanne, Switzerland,_ 5 _Pulmonary Medicine, Geneva University Hospital, Geneva, Switzerland,_ 6 _Pulmonary Medicine, Bern University Hospital, Bern, Switzerland,_ 7 _Pulmonary Medicine, Basel University Hospital, Basel, Switzerland,_ 8 _Lausanne-Geneva Lung Transplantation Center, Lausanne, Switzerland_

**(1253)** Leucopenia After Lung Transplantation: Incidence & Outcomes; __ M. Greer1, F. Ius2, T. Steinberg1, I. Tudorache2, T. Welte1, J. Gottlieb1. 1 _Respiratory Medicine, Hanover Medical School, Hannover, Germany,_ 2 _Heart, Thoracic, Transplantation & Vascular Surgery, Hanover Medical School, Hannover, Germany_

**(1254)** Three Years Experience with an IgM Enriched Human Intravenous Immunoglobulins Based Treatment for Patients with Early Donor Specific Antibodies After Lung Transplantation; __ F. Ius1, W. Sommer1, M. Verboom2, C. Kühn1, M. Avsar1, A. Knöfel1, T. Siemeni1, J. Salman1, D. Böthig1, M. Hallensleben2, T. Welte3, N. Schwerk4, C. Müller4, A. Haverich1, I. Tudorache1, G. Warnecke1. 1 _Department of Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany,_ 2 _Department of Transfusion Medicine, Hannover Medical School, Hannover, Germany,_ 3 _Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany,_ 4 _Department of Paediatric Pneumology, Hannover Medical School, Hannover, Germany_

**(1255)** Successful Maintenance Belatacept-Based Immunosuppression in Lung Transplantation Recipients Who Failed Calcineurin Inhibitors; __ C. J. Iasella, R. J. Winstead, C. A. Moore, B. A. Johnson, M. R. Morrell, J. Hayanga, A. Zeevi, E. A. Lendermon, J. F. McDyer, C. R. Ensor. _University of Pittsburgh, Pittsburgh, PA_

**(1256)** Intravenous Immune Globulin (IVIg) Monotherapy for Pre-Existing and De-Novo Donor-Specific Antibody (DSA) After Lung Transplantation (LTX); __ R. E. Girgis1, M. Strueber1, E. Beuker1, J. A. Gerlach2, A. Khaghani1. 1 _Richard DeVos Heart and Lung Transplant Program, Spectrum Health Hospitals, Grand Rapids, MI,_ 2 _Biomedical Laboratory Diagnostics Program, Michigan State University College of Human Medicine, East Lansing, MI_

**(1257)** The Effect of Immunosuppression on Airway Integrity; __ H. Bellon1, E. Vandermeulen1, S. E. Verleden1, T. Heigl1, H. Vriens2, E. Lammertyn1, L. Verlinden3, S. Götze4, M. Verstuyf3, P. M. Hoet2, R. Vos1, G. M. Verleden1, B. M. Vanaudenaerde1. 1 _Department of Clinical and Experimental Medicine, KU Leuven University, Leuven, Belgium,_ 2 _Environment and Health, KU Leuven University, Leuven, Belgium,_ 3 _Clinical and Experimental Endocrinology, KU Leuven University, Leuven, Belgium,_ 4 _Institut für Klinische Chemie, Universitätsmedizin Göttingen, Göttingen, Germany_

**(1258)** Lumacaftor-Ivacaftor Combination Therapy in Phe508del Homozygous CF Lung Transplant Candidates - Preliminary Results; __ C. Murer, L. C. Huber, T. Kurowski, A. Hirt, C. Robinson, U. Bürgi, C. Benden. _Pneumology, University Hospital Zurich, Zurich, Switzerland_

**(1259)** The Impact of Intravenous Immunoglobulin in Sensitized Lung Transplant Recipients with a cPRA <25%; __ A. L. Hulbert1, C. Benedetti1, K. Beermann1, A. Gray2, M. Hartwig3, J. M. Reymolds2. 1 _Pharmcy, Duke University Hospital, Durham, NC,_ 2 _Pulmonology, Duke University Hospital, Durham, NC,_ 3 _Surgery, Duke University Hospital, Durham, NC_

**(1260)** Outcomes of Recipients on Dual Compared to Triple Immunosuppression After Lung Transplantation; __ M. Nayyar, O. A. Shlobin, C. S. King, M. M. Fregoso, A. Verster, A. Cochrane, S. D. Nathan, A. W. Brown. _Inova Advanced Lung Disease & Transplant, Fairfax, VA_

**(1261)** Outcomes of Treatment of Donor Specific Antibodies: A Single Center Experience; __ D. Sullivan1, F. Torres1, A. Banga1, M. R. Mohanka1, S. Bollineni1, J. Mullins1, U. Rao1, C. Lacelle2, P. Duddupudi3, D. Surapaneni4, W. S. Ring5, M. Wait5, V. Kaza1. 1 _Division of Pulmonary and Critical Care Medicine, The University of Texas Southwestern Medical Center, Dallas, TX,_ 2 _Department of Pathology, The University of Texas Southwestern Medical Center, Dallas, TX,_ 3 _The University of Texas at Dallas, Dallas, TX,_ 4 _Michigan State University, East Lansing, MI,_ 5 _Department of Cardiovascular and Thoracic Surgery, The University of Texas Southwestern Medical Center, Dallas, TX_

**(1262)** A New Formulation of Itraconazole (Lozanoc®) Is Associated with Improved Bioavailability After Lung Transplantation; __ T. Tse, P. Hopkins, D. Chambers. _The Prince Charles Hospital, Brisbane, Australia_

**(1263)** Increasing Tacrolimus Time-in-Therapeutic Range Is Associated with Reduced Chronic Lung Allograft Dysfunction; __ C. A. Moore, K. M. Harrigan, C. J. Iasella, R. Venkataramanan, M. R. Morrell, J. Hayanga, J. D'Cunha, A. Zeevi, J. McDyer, C. R. Ensor. _University of Pittsburgh, Pittsburgh, PA_

**(1264)** Monthly Basiliximab Treatment Improves Chronic Renal Dysfunction with Allograft Stability After Lung Transplantation; __ D. J. Ross. _Department of Medicine, Division of Pulmonary and Critical Care Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA_

**(1265)** Predictors of Early Mortality After Lung Transplantation in the Lung Allocation Score Era; __ A. Banga, M. Mohanka, J. Mullins, S. Bollineni, V. Kaza, F. Torres. _UT Southwestern Medical Center, Dallas, TX_

**(1266)** Rothman Index Predicts Perioperative Outcomes After Lung Transplantation; __ S. Daouk1, H. Fakih1, L. Mramba2, T. Machuca3, S. Chandrashekaran1, A. Emtiazjoo1, I. Faruqi1, A. Pelaez1. 1 _Internal Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University of Florida, Gainesville, FL,_ 2 _Internal Medicine, Biostatistics, University of Florida, Gainesville, FL,_ 3 _Cardio-Thoracic Surgery, University of Florida, Gainesville, FL_

**(1267)** Demographic Disparities in Post-Lung Transplant Mortality; __ H. Maredia1, M. Bowring1, A. Massie1, S. Oyetunji1, C. Merlo2, R. Higgins1, D. Segev1, E. Bush1. 1 _Department of Surgery, Johns Hopkins University, Baltimore, MD,_ 2 _Department of Medicine, Johns Hopkins University, Baltimore, MD_

**(1268)** Lung and Heart Lung Transplantation for Scleroderma Lung Disease: Indications, Survival and Prognosis; __ P. Pradere1, J. Gottlieb2, B. Olivier3, B. Douvry4, M. Reynaud-Gaubert5, J. Claustre6, A. Le Borgne7, A. Holm8, H. Schultz9, S. Hirschi10, J. Le Pavec1. 1 _Service de Chirurgie Thoracique, Hôpital Marie Lannelongue, Le Plessis Robinson, France,_ 2 _Hannover Medical School, Biomedical Research in End-Stage and Obstructive Lung Disease, Hannover, Germany,_ 3 _Service de Pneumologie, Hôpital Bichat, Paris, France,_ 4 _Service de Pneumologie, Hôpital Fch, Suresnes, France,_ 5 _Service de Pneumologie, Hôpital Nord, Marseille, France,_ 6 _Service de Pneumologie, Clinique Universitaire de Pneumologie, Grenoble, France,_ 7 _Service de Pneumologie, CHU Toulouse, Toulouse, France,_ 8 _Hospital Rikshospitalet, Oslo University, Oslo, Norway,_ 9 _Hospital, Rigshospitalet, Copenhagen University, Copenhagen, Denmark,_ 10 _Service de Pneumologie, CHU Strasbourg, Strasbourg, France_

**(1269)** Body Mass Index Does Not Impact Long-Term Survival of Patients with Idiopathic Pulmonary Fibrosis Undergoing Lung Transplantation; __ E. B. Lushaj, J. Maloney, R. D. Cornwell, K. Meyer, N. De Oliveira. _University of Wisconsin, Madison, WI_

**(1270)** Fertility, Pregnancy and Child Birth in Women Post Lung Transplantation (a Single Center Experience); __ O. Shtraichman, I. Bakal, D. Rosengarten, D. Shitenberg, Y. Shostak, M. R. Kramer. _Pulmonary Institute, Rabin Medical Center Belinson Campus, Petach Tikva, Israel_

**(1272)** Lung Transplant Symposium: A Team's Ideas Put into Action; __ S. Mockett. _Transplant Center, Duke University Medical Center, Durham, NC_

**(1273)** Description of Airway Complications in Re-Transplantation: 10 Year Experience; __ J. C. Fernandez-Castillo1, R. R. Mehta2, E. Mahoney2, S. Quddus2. 1 _Loyola University Medical Center, Chicago, IL,_ 2 _Pulmonary and Critical Care Medicine, Loyola University Medical Center, Chicago, IL_

**(1274)** Extracorporeal Membrane Oxygenation (ECMO) as a Bridge to Lung Transplantation (Ltx) - Influence of Concomitant Mechanical Ventilation on Outcome; __ B. Zych, D. Garcia-Saez, O. Ananiadou, P. N. Mohite, A. Jothidasan, F. De Robertis, A. F. Popov, T. Bahrami, A. Reed, M. Carby, A. R. Simon. _Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Harefield Hospital. Royal Brompton and Harefield NHS Foundation Trust, Harefield, United Kingdom_

**(1275)** Effect of Gender Mismatch on Outcome in Lung Transplantation; __ R. Erlebach, Y. Yamada, M. Schuurmans, W. Jungraithmayr, I. Schmitt-Opitz, C. Benden, W. Weder, I. Inci. _University Hospital, Zurich, Switzerland_

**(1276)** One Hundred Cases of Lung Transplantation in Saudi Arabia: Challenges and Outcomes; __ M. H. Ahmed1, I. Y. Nizami2, W. N. Saleh1, S. M. Ahmed2, K. M. Alkattan3. 1 _Thoracic Surgery, King Faisal Specialist Hospital And Research Centre, Riyadh, Saudi Arabia,_ 2 _Organ Transplant Centre, King Faisal Specialist Hospital And Research Centre, Riyadh, Saudi Arabia,_ 3 _Alfaisal University, Riyadh, Saudi Arabia_

**(1277)** Donor Chest X-Ray and Bronchoscopy Findings Are Poor Predictive Measures for Lung Transplant Recipient Survival; __ A. Maniar1, F. Zafar2, R. Bryant III3, D. Morales3, C. Towe4, M. Schecter4. 1 _Department of Medicine, University of Cincinnati, Cincinnati, OH,_ 2 _Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH,_ 3 _Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH,_ 4 _Lung Transplant Department, Cincinnati Children's Hospital Medical Center, Cincinnati, OH_

**(1278)** A Downward Trajectory of Body Mass Index in the First 12 Months Post Lung Transplant Predicts Poor Survival; __ D. Hickling, J. McMillan, S. Yerkovich, D. C. Chambers, P. Hopkins. _Queensland Lung Transplant Service, Queensland Health, Brisbane, Australia_

**(1279)** WITHDRAWN

**(1280)** Tapering, Not Discontinuation, of Epoprostenol Prevents PGD Requiring ECMO Support in Recipients with Severe Pulmonary Hypertension; __ A. Aoyama1, H. Kinoshita2, T. Yoneda3, Y. Goda1, H. Oda1, H. Kayawake1, S. Ueda1, K. Minakata4, H. Motoyama1, M. Hamaji1, K. Hijiya1, T. F. Chen-Yoshikawa1, H. Date1. 1 _Thoracic Surgery, Kyoto University, Kyoto, Japan,_ 2 _Cardiovascular Medicine, Kyoto University, Kyoto, Japan,_ 3 _Clinical Laboratory, Kyoto University Hospital, Kyoto, Japan,_ 4 _Cardiovascular Surgery, Kyoto University, Kyoto, Japan_

**(1281)** Predictors of Survival in Lung Transplant Recipients Requiring Post-Operative ECMO: First National Analysis; __ M. S. Mulvihill, B. A. Yerokun, R. P. Davis, D. N. Ranney, M. A. Daneshmand, M. G. Hartwig. _Department of Surgery, Duke University, Durham, NC_

**(1282)** Gene Set Enrichment Analysis Identifies a Potential Link Between Smoking and Upregulation of Olfactory Receptor and Cytokine Enrichment Pathways; __ C. Schaufler1, J. Lasky1, B. Lim1, Y. Suzuki1, D. Mallem1, M. Oyster2, D. J. Lederer3, K. Meyer4, C. A. Bermudez1, J. Tobias5, V. M. Van Deerlin6, K. Olthoff1, A. Shaked1, J. M. Diamond2, E. Cantu1, J. D. Christie2. 1 _Division of Cardiovascular Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA,_ 2 _Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA,_ 3 _Department of Medicine and Epidemiology, Columbia University College of Physicians and Surgeons, New York, NY,_ 4 _University of Wisconsin School of Medicine and Public Health, Madison, WI,_ 5 _Penn Molecular Profiling Facility, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA,_ 6 _Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA_

**(1283)** Does PGD3 at 0-48 Hours After Lung Transplantation Matter?; __ A. Iyengar1, O. Kwon2, N. Harati1, C. Eisenring2, E. DePasquale3, D. Ross4, A. Ardehali2. 1 _David Geffen School of Medicine, University of California - Los Angeles, Los Angeles, CA,_ 2 _Department of Cardiac Surgery, University of California - Los Angeles, Los Angeles, CA,_ 3 _Department of Cardiology, University of California - Los Angeles, Los Angeles, CA,_ 4 _Department of Pulmonology, University of California - Los Angeles, Los Angeles, CA_

**(1284)** Effectiveness of Inhaled Nitric Oxide (NO) in Lung Transplantation: Clinical and Morphological Study; __ F. Calabrese1, E. Forin2, M. Schiavon1, E. Perissinotto2, N. Cacco2, G. Marulli1, F. Lunardi2, S. Vuljan2, G. Di Gregorio2, F. Rea1. 1 _Cardiac, Thoracic and Vascular Sciences, University of Padua, Padova, Italy,_ 2 _University of Padua, Padova, Italy_

## Mechanical Circulatory Support

(Seaport Foyer)

**Poster Discussants:** David A Baran, MD (USA), Christian A Bermudez, MD (USA), Andrew J Boyle, MD (USA), Patricia P Chang, MD (USA), Dawn M Christensen, MS, CRNP (USA), Eric Epailly, MD (France), Matthew Fenton, MRCPCH (United Kingdom), Jaime A Hernandez-Montfort, MD, MPH (USA), Theodoros Kofidis, MD, PhD, FRCS (Singapore), Claudius Mahr, DO (USA), Francis D Pagani, MD, PhD (USA), Maryse Palardy, MD (USA), Sebastian V Rojas, MD (Germany), Melana Yuzefpolskaya, MD (USA)

**(1285)** Lung Function and Survival in Patients with Left Ventricular Assist Devices; __ P. Sajgalik, C. Kim, J. M. Stulak, D. L. Joyce, S. Kushwaha, L. D. Joyce, S. Maltais, B. D. Johnson, J. A. Schirger. _Cardiovascular Diseases, Mayo Clinic, Rochester, MN_

**(1286)** Dissecting the INTERMACS Definition of Right Heart Failure: Can We Really Predict Central Venous Pressure?; __ J. M. Joly, A. El-Dabh, R. Marshell, A. Chatterjee, M. G. Smith, M. Tresler, J. K. Kirklin, D. Acharya, I. N. Rajapreyar, J. A. Tallaj, S. V. Pamboukian. _University of Alabama at Birmingham, Birmingham, AL_

**(1287)** Managing Driveline Repairs in Total Artificial Heart Patients: A Single Center Experience; __ H. Barone, J. Hajj, C. Runyan, N. Huie, R. Jocson, D. Geft, E. Passano, L. Czer, J. Moriguchi, J. A. Kobashigawa, F. Arabia. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(1288)** Morbidity Risks with Long Term Left Ventricular Assist Device (LVAD) Support; __ S. Schettle1, N. Pereira2, S. Kushwaha2, R. Daly1, D. Joyce1, L. Joyce1, S. Maltais1, J. Stulak1. 1 _Cardiovascular Surgery, Mayo Clinic Rochester, Rochester, MN,_ 2 _Cardiology, Mayo Clinic Rochester, Rochester, MN_

**(1289)** Risk Factors for the Development of Right Ventricular Failure After LVAD Implantation - A Single Centre Retrospective on Echocardiographic Speckle Tracking Findings; __ R. Zayat, N. Bögerhausen, A. Goetzenich, L. Tewarie, A. Moza, R. Autschbach, N. Hatam. _Department of Thoracic and Cardiovascular Surgery, RWTH University Hospital, Aachen, Germany_

**(1290)** Unexpected Mechanical Device Failures of Left Ventricular Assist Devices: An Urgent Call for More Intensive Regular Inspections; __ R. Muslem1, S. Akin1, A. A. Constantinescu1, C. Van der Heiden1, O. C. Manintveld1, O. Birim2, A. J. Bogers2, K. Caliskan1. 1 _Cardiology, Erasmus MC, Rotterdam, Netherlands,_ 2 _Cardiothoracic Surgery, Erasmus MC, Rotterdam, Netherlands_

**(1291)** Extracorporeal Life Support (ECLS) as Bridge to Ventricular Assist Device (VAD) Implantation, Friend or Foe?; __ H. Carstens1, N. Pizanis1, A. Koch1, J. Heckmann1, T. Rassaf2, M. Kamler1. 1 _Thoracic Transplant, University Essen, Essen, Germany,_ 2 _Cardiology, University Essen, Essen, Germany_

**(1292)** Prognostic Relevance of INTERMACS Defined Right Heart Failure After Left Ventricular Assist Device Implantation; __ R. Muslem1, C. Ong2, N. A. Gilotra2, K. Sharma2, B. A. Houston3, K. J. Zehr2, D. C. Duquaine2, G. J. Whitman4, K. Caliskan1, S. D. Russell2, R. J. Tedford2. 1 _Cardiology, Erasmus MC, Rotterdam, Netherlands,_ 2 _Cardiology, Johns Hopkins School of Medicine, Baltimore, MD,_ 3 _Cardiology, Medical University of South Carolina, Charleston, SC,_ 4 _Cardiothoracic Surgery, Johns Hopkins School of Medicine, Baltimore, MD_

**(1293)** D-dimer as a Prognostic Indicator for Survival or Death in Mechanical Circulatory Support Device Patients; __ T. Kazui1, R. H. Cosgrove2, D. A. Hewlett2, R. L. Basken2, R. G. Smith3, R. J. Avery4, P. G. Suryanarayana5, E. B. Juneman5, J. L. Cook5, S. D. Lick1, N. K. Sweitzer5, Z. I. Khalpey1. 1 _Cardiothoracic Surgery, Banner University Medical Center Tucson, Tucson, AZ,_ 2 _Pharmacy, Banner University Medical Center Tucson, Tucson, AZ,_ 3 _Artificial Heart, Banner University Medical Center Tucson, Tucson, AZ,_ 4 _Radiology, Banner University Medical Center Tucson, Tucson, AZ,_ 5 _Cardiology, Sarver Heart Center, Banner University Medical Center Tucson, Tucson, AZ_

**(1294)** Predicting Right Ventricular Failure in the Current Continuous Flow Left Ventricular Assist Device Era; __ A. Loforte1, A. Montalto2, V. Polizzi3, F. Sbaraglia3, M. Lo Presti3, L. Potena4, M. Masetti4, F. Grigioni4, G. Marinelli1, F. Musumeci2. 1 _Cardiovascular Surgery and Transplantation, S. Orsola-Malpighi Hospital, Bologna University, Bologna, Italy,_ 2 _Cardiac Surgery and Transplantation, S. Camillo-Forlanini Hospital, Rome, Italy,_ 3 _Cardiology and Transplantation, S. Camillo-Forlanini Hospital, Rome, Italy,_ 4 _Cardiology and Transplantation, S. Orsola-Malpighi Hospital, Bologna University, Bologna, Italy_

**(1295)** Predictors of Acute Kidney Injury Following Left Ventricular Assist Device Implantation; __ B. Lima1, J. Collier1, A. Shaikh1, K. M. Tecson2, S. Still1, R. D. Baxter1, J. Felius1, S. A. Hall1, G. V. Gonzalez-Stawinski1, S. M. Joseph1. 1 _Baylor University Medical Center, Dallas, TX,_ 2 _Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, TX_

**(1296)** Long Term Survivors of LVAD Support: What Attributes Describe Their Survival Advantage?; __ J. A. Cowger1, P. Shah2, R. Singh3, F. D. Pagani4, K. D. Aaronson5, T. F. Dardas6, S. Maltais7, N. A. Mokadam8, J. Stulak7, S. M. Dunlay9, C. T. Salerno10. 1 _Cardiovascular Medicine, St. Vincent Heart Center of Indiana, Indianapolis, IN,_ 2 _Cardiovascular Medicine, Inova Heart & Vascular, Fall Church, VA, _3 _Surgery, Inova Heart & Vascular, Falls Church, VA, _4 _Cardiac Surgery, University of Michigan, Ann Arbor, MI,_ 5 _Cardiovascular Medicine, University of Michigan, Ann Arbor, MI,_ 6 _Cardiovascular Medicine, University of Washington, Seattle, WA,_ 7 _Cardiac Surgery, Mayo Clinic, Rochester, MN,_ 8 _Cardiovascular Surgery, University of Washington, Seattle, WA,_ 9 _Cardiovascular Medicine, Mayo Clinic, Rochester, MN,_ 10 _Cardiac Surgery, St. Vincent Heart Center of Indiana, Indianapolis, IN_

**(1297)** Elevated Pre-Operative Creatinine Is a Risk Factor for Late-Onset Right Heart Failure After Left Ventricular Assist Device Implantation; __ J. Kim, A. Pekarek, D. Nguyen, J. Vega, R. Cole, A. A. Morris, A. Smith, S. Laskar, D. Gupta. _Emory University, Atlanta, GA_

**(1298)** Effect of a Multifaceted Team Management Approach on Survival and Stroke Rates in Heartmate 2 Recipients; __ U. Jorde, N. Siddiqi, A. Luke, D. B. Sims, O. Saeed, S. R. Patel, S. Murthy, J. Shin, S. Watts, E. Borukhov, S. Madan, S. Thompson, R. Bello, S. Forest, S. Vukelic, C. Nucci, S. Rangasamy, D. Goldstein. _Medicine, Albert Einstein College of Medicine Montefiore Medical Center, Bronx, NY_

**(1299)** Clinical Relevance of Late and Very Late Right Heart Failure After LVAD Implantation; __ H. Vidula, S. McNitt, A. Papernov, M. Wang, V. Kutyifa, J. D. Alexis. _Medicine, Univ of Rochester, Rochester, NY_

**(1300)** Predicting Right Ventricular Failure in Patients Undergoing Continuous Flow-Left Ventricular Assist Device Implantation with Multiple Predictive Models; __ L. Smith, A. Peters, B. Lawlor, D. Harrison, E. Benton, L. Kirchoff, K. Bilchick, J. Kennedy, S. Mazimba. _University of Virginia, Charlottesville, VA_

**(1301)** Allosensitization in New Generation Left Ventricular Assist Device Recipients; __ M. Carrozzini1, T. Bottio1, V. Tarzia1, F. Toto1, M. Comisso1, E. Manzan1, M. Cardillo2, E. Cozzi1, J. Bejko1, G. Gerosa1. 1 _Cardiac, Thoracic and Vascular Sciences, University of Padova, Cardiac Surgery Unit, Padova, Italy,_ 2 _Rigenerative Medicine, Milano Hospital, Transplant Immunology, Milano, Italy_

**(1302)** Outcomes and Predictors of Lymphatic Leak Following Femoral Cannulation for Veno Arterial Extracorporeal Life Support; __ M. F. Masood, W. Padovano, M. Pisani, K. Balsara, A. Itoh. _Cardiothoracic Surgery, Washington University in St. Louis / Barnes Jewish Hospital, Saint Louis, MO_

**(1303)** Pre-Implant Under-Expression of CCR3 and Its Ligands Predicts One-Year Mortality in Left Ventricular Assist Device Patients; __ A. Nayak1, C. Neill2, R. L. Kormos3, L. Lagazzi3, I. Halder4, C. McTiernan4, J. Larsen2, A. Inashvili1, J. Teuteberg3, T. N. Bachman5, K. Hanley-Yanez4, D. M. McNamara3, M. A. Simon3. 1 _Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA,_ 2 _School of Medicine, University of Pittsburgh, Pittsburgh, PA,_ 3 _Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA,_ 4 _Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh Medical Center, Pittsburgh, PA,_ 5 _Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA_

**(1304)** Readmission within 30 Days After Continuous Flow Ventricular Assist Devices Implantation - Comparative Analysis of HeartMate II and HeartWare Devices; __ T. Sugiura, C. Kurihara, M. Kawabori, W. E. Cohn, A. B. Civitello, O. H. Frazier, J. A. Morgan. _Texas Heart Institute, Houston, TX_

**(1305)** Heparin Induced Thrombocytopenia Type II in Mechanical Circulatory Support Recipients; __ M. Urban, J. Jungschleger, N. Robinson-Smith, A. Woods, S. Schueler, G. MacGowan. _Freeman Hospital, Newcastle upon Tyne, United Kingdom_

**(1306)** Iron Deficiency Prior to cf-LVAD Implant Predicts Anemia Post Implant; __ R. J. Varipapa1, J. M. Canada2, K. B. Shah1. 1 _VCU, Richmond, VA,_ 2 _Pauley Heart Center, VCU, Richmond, VA_

**(1307)** Model of End-Stage Liver Disease (MELD) and MELD-Sodium Scoring Systems Predict Development of Early Right Heart Failure in Patients Undergoing Ventricular Assist Device Implant; __ A. F. Stein-Merlob1, M. A. Psotka1, J. Svetlichnaya1, V. N. Selby1, M. Janmohamed1, T. De Marco1, G. M. Wieselthaler2, L. Klein1. 1 _Cardiology, Univ of California, San Francisco, CA,_ 2 _Cardiac Surgery, Univ of California, San Francisco, CA_

**(1308)** The Short-to-Shield Phenomenon in Heartmate II Left Ventricular Assist Devices: A Single Center Experience; __ H. Ilias Basha, R. C. Givens, B. Cagliostro, G. Parkins, M. Flannery, R. Te-Frey, A. R. Garan, M. Yuzefpolskaya, H. Takayama, K. Takeda, Y. Naka, M. A. Farr, P. C. Colombo, V. K. Topkara. _Columbia University, New York, NY_

**(1309)** An Evaluation of Long-Term Durability of the Motor and Driveline of the HVAD System; __ M. Koprivanac1, D. T. Pham2, S. Raza3, D. Meyer4, C. Klodell5, C. Salerno6, M. Kelava7, J. Chow8, J. Graham9, N. Moazami3. 1 _General Surgery/Cardiothoracic Surgery, Cleveland Clinic, Cleveland, OH,_ 2 _Cardiothoracic Surgery, Northwestern University, Chicago, IL,_ 3 _Cardiothoracic Surgery, Cleveland Clinic, Cleveland, OH,_ 4 _Cardiothoracic Surgery, UT Southwestern Medical Center, Dallas, TX,_ 5 _Cardiothoracic Surgery, Division of Thoracic and Cardiovascular Surgery University of Florida, Gainesville, OH,_ 6 _Cardiothoracic Surgery, St. Vincent's Heart Center of Indiana, Indianapolis, IN,_ 7 _Cardiac Anestesiology, Cleveland Clinic, Cleveland, OH,_ 8 _Medical Affairs, HeartWare, Medical Affairs, HeartWare, Framingham, MA,_ 9 _Medical Affairs, HearWare, Medical Affairs, HearWare, | Framingham, MA_

**(1310)** Cerebrovascular Events in Patients with Continuous Flow Left Ventricular Assist Devices; __ Y. D. Kim, D. Robson, P. S. Macdonald, P. Spratt, P. Jansz, C. S. Hayward. _St Vincent's Hospital, Sydney, Australia_

**(1311)** Late-Onset Right Heart Failure After Left Ventricular Assist Device Implantation Is Associated with Poor Prognosis; __ J. Kim, A. Pekarek, D. Nguyen, J. Vega, R. Cole, A. Morris, A. Smith, S. Laskar, D. Gupta. _Emory University, Atlanta, GA_

**(1312)** RA Pressure and RV Enlargement Are Predictive of Heart Failure Hospitalizations in Patients with LVAD; __ J. Pillarella, G. Vaidya, B. Salgado, C. Dunbar Matos, R. Vijayakrishnan, A. Lenneman, M. Slaughter, E. Birks, D. Abramov. _Division of Cardiovascular Medicine, University of Louisville, Louisville, KY_

**(1313)** Venoarterial Extracorporeal Membrane Oxygenation as a Direct Bridge to Heart Transplant; __ J. Sahbaz1, E. P. Kastner1, Z. N. Kon2, E. D. Feller3, V. Ton3, S. M. Pham2, E. N. Sorensen4, G. V. Ramani3. 1 _Department of Medicine, University of Maryland School of Medicine, Baltimore, MD,_ 2 _Department of Surgery, Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD,_ 3 _Department of Medicine, Division of Cardiovascular Medicine, University of Maryland School of Medicine, Baltimore, MD,_ 4 _Division of Clinical Engineering, University of Maryland School of Medicine, Baltimore, MD_

**(1314)** Circadian Variation in Hemodynamics and Device Parameters in HeartMate II Patients; __ A. Pinsino1, F. Castagna1, E. J. Stöhr1, B. McDonnell2, M. Yuzefpolskaya1, A. Clemons1, M. Tiburcio1, M. Pineda1, K. Ross1, V. K. Topkara1, A. R. Garan1, H. Takayama1, K. Takeda1, Y. Naka1, J. Cockcroft2, P. C. Colombo1. 1 _New York Presbyterian Hospital - Columbia University Medical Center, New York, NY,_ 2 _Cardiff Metropolitan University, Cardiff, United Kingdom_

**(1315)** Immediate ECMO Support After Heart Transplantation: Does It Portend Reasonable Outcome?; __ J. A. Kobashigawa, F. Esmailian, T. Aintablian, D. Ramzy, A. Trento, J. Chung, J. Moriguchi, L. Czer, D. H. Chang, M. Hamilton, M. Kittleson. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(1316)** Characteristics and Outcomes of LVAD Recipients with Cardiac Sarcoidosis; __ S. Ahmed1, S. F. Mohammed1, D. T. Majure2, M. E. Rodrigo1, E. J. Molina1, S. W. Boyce1, S. S. Najjar1, F. H. Sheikh1. 1 _MedStar Heart and Vascular Institute, MedStar Washington Hospital Center, Washington, DC,_ 2 _Advanced Heart Failure, Northwell Health, New York, NY_

**(1317)** Outcomes of Extra Corporeal Membrane Oxygenation by Etiology: A Single Center Experience; __ D. Miranda1, B. Magod2, K. Wilson2, R. Garberich2, D. Williams3, K. Hryniewicz1. 1 _Minneapolis Heart Institute, Abbott Northwestern Hospital, Minneapolis, MN,_ 2 _Minneapolis Heart Institute Foundation, Minneapolis, MN,_ 3 _Critical Care Medicine, Abbott Northwestern Hospital, Minneapolis, MN_

**(1318)** The Impact of LVAD Duration on Short-Term Outcomes After Heart Transplantation; __ H. Shah1, M. Kahanda1, E. Novak2, S. Sitner2, J. Shuster2, S. LaRue2, J. Schilling2. 1 _Barnes Jewish Hospital/Washington University, Saint Louis, MO,_ 2 _Cardiology, Barnes Jewish Hospital/Washington University, Saint Louis, MO_

**(1319)** Utilization of Physical and Occupational Therapy Services in Patients Awaiting Heart Transplant with an Ambulatory Durable Counterpulsation System; __ M. Stulberg1, C. Esbrook1, V. Kagan2, C. Juricek2, V. Jeevanandam2. 1 _Therapy Services, University of Chicago Medicine, Chicago, IL,_ 2 _Cardiac & Thoracic Surgery, University of Chicago Medicine, Chicago, IL_

**(1320)** Conservative Weight Reduction Is Insufficient in Obese Patients Receiving a Left-Ventricular Assist Device as Bridge-to-Candidacy; __ P. Angleitner1, D. Wiedemann1, T. Schlöglhofer2, J. Riebandt1, K. Dimitrov1, A. Zuckermann1, G. Laufer1, D. Zimpfer1. 1 _Cardiac Surgery, Medical University of Vienna, Vienna, Austria,_ 2 _Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria_

**(1321)** Hemoglobin Level at 3 Months Post-Durable Mechanical Circulatory Support Device Implantation and Mortality; __ S. Zalawadiya, M. Keebler, A. Shah, M. Wigger, M. Djunaidi, K. Schlendorf, D. Choi, H. Ooi, S. Brown-Sacks, N. Haglund, M. Danter, M. Brinkley, J. Lindenfeld. _Vanderbilt University Medical Center, Nashville, TN_

**(1322)** Echocardiographic Features and Prognosis of Aortic Regurgitation in Patients with Left Ventricle Assist Device; __ M. Zemedkun, S. Mohammed, Z. Wang. _Cardiology, MedStar Washington Hospital Center, Washington, DC_

**(1323)** Single Center Experience of Long Term Outcomes of Severe Cardiogenic Shock Patients Needing IMPELLA 5.0 Placement; __ S. H. Ibarra-Cortez, R. Araujo-Gutierrez, A. S. Cruz-Solbes, B. Bruckner, J. D. Estep, E. E. Suarez, A. Bhimaraj. _DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, TX_

**(1324)** Ventricular Arrhythmias in Long Term LVAD Patients - Life Threatening Situation or Nothing to Worry About?; __ J. G. Jungschleger, M. M. Mydin, A. Woods, M. Urban, N. Robinson, G. MacGowan, S. Schueler. _Dept of Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, United Kingdom_

**(1325)** Impact of Temporary Mechanical Circulatory Support Prior to Durable Left Ventricular Assist Device Implantation on Hospital Costs and Survival; __ A. Peters, L. Smith, B. Lawlor, K. Bilchick, D. Harrison, E. Benton, L. Kirchoff, J. Kennedy, S. Mazimba. _University of Virginia Health System, Charlottesville, VA_

**(1326)** WITHDRAWN

**(1327)** WITHDRAWN

**(1328)** Comparison Between Italian and Unites States Centers on Outcome and Likelihood of Heart Transplantation in Patients Treated with Left Ventricular Assist Device as Bridge to Transplantation; __ E. Ammirati1, M. Brambatti2, M. Cipriani1, E. Perna1, A. Mizeracki2, J. Silva Enciso2, H. Tran2, A. R. Calini1, G. V. Pretorius3, C. F. Russo1, M. Frigerio1, E. Adler2. 1 _De Gasperis CardioCenter, Niguarda Hospital, Milan, Italy,_ 2 _Cardiology, University of California San Diego, La Jolla, CA,_ 3 _Cardiothoracic Surgery, University of California San Diego, La Jolla, CA_

**(1329)** Effects of Body Mass Index on Survival, Length of Stay, Infection, and Strokes After Left Ventricular Assist Device Implantation; __ A. Phancao, D. Horstmanshof, S. Jones, N. Chelikani, M. El Banayosy, K. Nelson, J. Long. _Advanced Cardiac Care, INTEGRIS Baptist Medical Center, Oklahoma City, OK_

**(1330)** Effective Mechanical Circulatory Support with Impella in Postcardiotomy Cardiogenic Shock; __ D. G. Tang1, G. W. Vetrovec2, C. Toma3, A. B. Civitello4, M. Silver5, M. B. Anderson6. 1 _Virginia Commonwealth University, Richmond, VA,_ 2 _Cardiology, Virginia Commonwealth University, Richmond, VA,_ 3 _Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA,_ 4 _Baylor St. Luke's Medical Center / Texas Heart Institute, Houston, TX,_ 5 _Genesys Regional Medical Center, Grand Blanc, MI,_ 6 _Cardiothoracic Surgery, Einstein Medical Center, Philadelphia, PA_

**(1331)** Effect of Pre-Durable Mechanical Circulatory Support Device Anemia on Post-Device Implant Mortality; __ S. Zalawadiya, J. Lindenfeld, K. Schlendorf, M. Danter, M. Djunaidi, M. Wigger, A. Shah, H. Ooi, S. Brown-Sacks, N. Haglund, M. Brinkley, M. Keebler. _Vanderbilt University Medical Center, Nashville, TN_

**(1332)** Increasing Severity of Periprocedural Right Heart Failure Leads to Incrementally Worse Outcomes Following Left Ventricular Assist Device Implantation; __ B. Lima1, A. Shaikh1, K. M. Tecson2, S. Still1, J. Collier1, R. D. Baxter1, J. Felius1, S. A. Hall1, G. V. Gonzalez-Stawinski1, S. M. Joseph1. 1 _Baylor University Medical Center, Dallas, TX,_ 2 _Baylor Heart and Vascular Institute, Baylor University Medical Center, Dallas, TX_

**(1333)** Prolonged Ventilator Dependence Following LVAD Implant Is an Independent Predictor of Reduced Survival; __ K. Balsara, L. Jolliff, M. Masood, A. Itoh. _Surgery, Washington University in St Louis, St Louis, MO_

**(1334)** Biventricular Pacing Does Not Seem to Provide Any Clinical Benefit Over RV Pacing or Intrinsic Rhythm in Most LVAD Patients; __ C. Inampudi, C. Johnson, K. Jenn, J. Franzwa, H. Doshi, A. Mazur, M. Giudici, V. Cotarlan. _Univ of Iowa Hospital, Iowa City, IA_

**(1335)** Does Socioeconomic Status Impact Outcome Following Mechanical Circulatory Support Device Implantation?; __ D. H. Chang, M. Kittleson, J. Patel, T. Aintablian, M. Hamilton, D. Geft, E. Kransdorf, L. Czer, J. A. Kobashigawa, F. Arabia, J. Moriguchi. _Cedars-Sinai Heart Institute, Los Angeles, CA_

**(1336)** Post-Hospital Care in LVAD Patients - Experiences of Two Large German Heart Centers; __ T. Schmidt1, N. Reiss1, J. D. Hoffmann1, C. Feldmann2, E. Deniz2, K. Roske2, R. Bach1, S. Schulte-Eistrup1, D. Willemsen1, J. D. Schmitto2. 1 _Schüchtermann Klinik, Bad Rothenfelde, Germany,_ 2 _Hannover Medical School, Hannover, Germany_

**(1337)** Where Do Patients with VADs Prefer to Spend Their Last Days?; __ S. G. Cooper, C. G. Caballero, C. Mahr, N. A. Mokadam, J. N. Kirkpatrick. _University of Washington, Seattle, WA_

**(1338)** Peak Oxygen Consumption and VE/VCO2 Correlates with 6 Minutes' Walk Test in Patients Supported with Continuous Flow LVAD; __ A. Padegimas1, E. S. Pak2, T. C. Hanff2, J. A. Mazurek2, M. E. Seigerman1, J. Menachem2, J. Marble2, L. R. Goldberg2, J. Wald2, P. Atluri3, J. E. Rame2, E. Y. Birati2. 1 _Internal Medicine, University of Pennsylvania, Philadelphia, PA,_ 2 _Cardiology, University of Pennsylvania, Philadelphia, PA,_ 3 _Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA_

**(1339)** Impact of Support Period and Type of Ventricular Assist Device on Patient Survival After Heart Transplantation: Japanese Heart Transplantation Registry 2016; __ N. Fukushima1, M. Ono2, Y. Saiki3, Y. Sawa4. 1 _Department of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Japan,_ 2 _Department of Cardiac Surgery, University of Tokyo, Tokyo, Japan,_ 3 _Department of Caridovascular Surgery, Tohoku University, Sendai, Japan,_ 4 _Department of Cardiovascular Surgery, Osaka Univeristy, Suita, Japan_

**(1340)** A Subcostal Approach Is Favorable Compared to Full Sternotomy for Continuous-Flow Left Ventricular Assist Device Exchange; __ H. Kitahara, C. Juricek, D. Onsager, J. Reikhelkar, G. Kim, N. Sarswat, S. Adatya, G. Sayer, N. Uriel, T. Song, V. Jeevanandam, T. Ota. _Cardiac Surgery, The University of Chicago, Chicago, IL_

**(1341)** A Novel Technique for Measuring Outflow Graft Length During HeartMate II Left Ventricular Assist Device Implant; __ J. P. Slater1, L. Suplicki2, M. Goldschmidt3. 1 _Cardiothoracic Surgery, Morristown Medical Center, Morristown, NJ,_ 2 _Heart Success, Morristown Medical Center, Morristown, NJ,_ 3 _Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ_

**(1342)** A New Cannulation Technique for Ambulatory Percutaneous RVAD; __ T. H. Song1, T. Wombacher1, H. Kitahara1, D. Onsager1, T. Ota1, N. Uriel2, V. Jeevanandam1. 1 _Section of Cardiac and Thoracic Surgery, University of Chicago, Chicago, IL,_ 2 _Section of Cardiology, University of Chicago, Chicago, IL_

**(1343)** Percutaneous Subclavian Intra-Aortic Balloon Pump: An Evolving Technique; __ T. Wombacher, C. Juricek, R. Piech, T. Ota, N. Uriel, V. Jeevanandam, T. Song. _Cardiac & Thoracic Surgery, University of Chicago, Chicago, IL_

**(1344)** Transcatheter Aortic Valve Replacement Management of Aortic Insufficiency in Patients with Left Ventricular Assist Device Support; __ B. Kar, P. Prathipati, F. Y. Macedo, S. Nathan, R. Radovancevic, P. Loyalka, I. D. Gregoric. _The University of Texas Health Science Center at Houston, Houston, TX_

**(1345)** Moderate Hypothermia Technique for Chronic Implantation of a Total Artificial Heart in Calves; __ J. H. Karimov, P. Grady, M. Sinkewic, R. Dessoffy, N. Byram, N. Moazami, K. Fukamachi. _The Cleveland Clinic, Cleveland, OH_

**(1346)** Clinical Benefits and Complications in Patients with Percutaneous VAD versus Surgical LV Vent with ECLS: Multicenter REgiStry for Cardiogenic Shock - Utilization and Efficacy of Device Therapy (RESCUE); __ A. Itoh1, M. Pisani1, M. Baltalzar1, K. R. Balsara1, M. F. Masood1, S. Tepper1, J. Han2, D. Ranney3, M. Daneshmand3, B. Sun4, M. Kai5, M. Camacho6, H. Takayama7. 1 _Surgery, Washington University in St. Louis, Saint Louis, MO,_ 2 _Surgery, Columbia University, New York, NY,_ 3 _General and Thoracic Surgery, Duke University, Durham, NC,_ 4 _Cardiothoracic Surgery, Mineapolis Heart Institute, Minneapolis, MN,_ 5 _Cardiothoracic Surgery, Westchester Medical Center, Valhalla, NY,_ 6 _Cardiothoracic Surgery, Newark Beth Israel Medical Center, Newark, NJ,_ 7 _Cardiothoracic Surgery, Columbia University, New York, NY_

**(1347)** Bridge to Transplantation with Long-Term Mechanical Assist Device in Adults with Transposition of the Great Arteries; __ E. J. Orozco Hernandez1, D. H. Enter1, M. Monge2, J. Nakano1, J. Rich3, A. Anderson3, C. Backer2, M. McCarthy1, D. T. Pham1. 1 _Cardiac Surgery, Northwestern Memorial Hospital, Chicago, IL,_ 2 _Congenital Cardiac Surgery, Northwestern Memorial Hospital, Chicago, IL,_ 3 _Cardiology, Northwestern Memorial Hospital, Chicago, IL_

**(1348)** Single Center Experience of Minimally-Invasive Left Ventricular Assist Device Implantation; __ D. Reichart1, C. Brand1, A. Schäfer1, S. Schmidt1, T. Deuse2, F. Wagner1, A. Bernhardt1, H. Reichenspurner1, M. Barten1. 1 _Univ Hamburg Heart Center, Hamburg, Germany,_ 2 _University of California-San Francisco, San Francisco, CA_

**(1349)** A Minimaly Invasive Left Ventricular Asssist Device Surgical Appraoch Is More Durable at Protecting Right Ventricular Function Than a Full Sternotomy; __ T. Kazui1, P. G. Suryanarayana2, S. Singh2, R. G. Smith3, R. J. Avery4, E. B. Juneman2, J. L. Cook2, N. K. Sweitzer2, S. D. Lick1, Z. I. Khalpey1. 1 _Cardiothoracic Surgery, University of Arizona Medical Center, Tucson, AZ,_ 2 _Cardiology, Sarver Heart Center, Banner University Medical Center Tucson, Tucson, AZ,_ 3 _Artificial Heart, University of Arizona Medical Center, Tucson, AZ,_ 4 _Radiology, Banner University Medical Center Tucson, Tucson, AZ_

**(1350)** Concomitant Tricuspid Valve Replacement with a Continuous-Flow Left Ventricular Assist Device in Patients with Severe Tricuspid Regurgitation and Marginal Right Ventricular Function; __ K. Takeda, H. Takayama, J. Han, A. R. Garan, V. K. Topkara, P. Kurlansky, M. Yuzefpolskaya, M. A. Farr, P. C. Colombo, Y. Naka. _Columbia University, NY, NY_

**(1351)** Minimally Invasive Off Pump HVAD Placement in Redo Patients: Is It a Better Approach?; __ T. Kazui1, S. D. Lick1, R. G. Smith2, R. J. Avery3, P. G. Suryanarayana4, E. B. Juneman4, J. L. Cook4, N. K. Sweitzer4, Z. I. Khalpey1. 1 _Cardiothoracic Surgery, Banner University Medical Center Tucson, Tucson, AZ,_ 2 _Artificial Heart, Banner University Medical Center Tucson, Tucson, AZ,_ 3 _Radiology, Banner University Medical Center Tucson, Tucson, AZ,_ 4 _Cardiology, Sarver Heart Center, Banner University Medical Center Tucson, Tucson, AZ_

**(1352)** Technology and Techniques: Tools to Mitigate Adverse Events and Improve Survival in Left Ventricular Assist Device Patients; __ V. Tarzia1, G. Di Giammarco2, M. Maccherini3, M. Maiani4, P. Agostoni5, L. Bagozzi1, D. Marinelli2, V. Tursi4, A. Apostolo5, S. Bernazzali3, J. Bejko1, H. Ortis4, M. Di Mauro2, A. Dokollari3, G. Bortolussi1, F. Alamanni5, G. Sani3, T. Bottio1, U. Livi4, G. Gerosa1. 1 _Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Cardiac Surgery, Padova, Italy,_ 2 _Cardiac Surgery, University of Chieti, Chieti, Italy,_ 3 _Cardiac Surgery, University of Siena, Siena, Italy,_ 4 _Cardiac Surgery, University of Udine, Udine, Italy,_ 5 _Cardiac Surgery, University of Milan, Milan, Italy_

**(1353)** Minimally Invasive Off-Pump HVAD vs Full Sternotomy On-Pump LVAD Placement: A Better Option?; __ T. Kazui1, S. D. Lick1, R. G. Smith2, R. J. Avery3, P. G. Suryanarayana4, E. B. Juneman4, J. L. Cook4, N. K. Sweitzer4, Z. I. Khalpey1. 1 _Cardiothoracic Surgery, Banner University Medical Center Tucson, Tucson, AZ,_ 2 _Artificial Heart, Banner University Medical Center Tucson, Tucson, AZ,_ 3 _Radiology, Banner University Medical Center Tucson, Tucson, AZ,_ 4 _Cardiology, Sarver Heart Center, Banner University Medical Center Tucson, Tucson, AZ_

**(1354)** Short-Term Results with Minimally Invasive Implantation Technique vs Conventional Sternotomy Technique Implantation of New Generation Left Ventricular Assist Device; __ U. Kervan1, S. S. Kocabeyoglu1, A. Temizhan2, B. Demirkan2, D. E. Sert1, E. Aygun1, Y. Güray2, M. Pac1. 1 _Cardiovascular Surgery, Turkey Yuksek Ihtisas Hospital, Ankara, Turkey,_ 2 _Cardiology, Turkey Yuksek Ihtisas Hospital, Ankara, Turkey_

**(1355)** Minimally Invasive Left Ventricular Assist Device Implantation: Which One HeartWare or HeartMate3?; __ S. S. Kocabeyoglu1, U. Kervan1, D. E. Sert1, B. Demirkan2, Y. Guray2, Z. Catav1, O. Beyazal1, U. Unal1, M. Pac1. 1 _Cardiovascular Surgery, Turkey Yuksek Ihtisas Hospital, Ankara, Turkey,_ 2 _Cardiology, Turkey Yuksek Ihtisas Hospital, Ankara, Turkey_

**(1356)** Comparison of Activated Partial Thromboplastin Time (aPTT) and Anti-Factor Xa for Low Intensity Unfractionated Heparin Monitoring in Patients with Mechanical Circulatory Support Devices (MCSD); __ O. Volod1, L. D. Lam2, M. Barglowski1, J. Mirocha3, C. Runyan2, J. Moriguchi4, L. S. Czer4, F. Arabia5. 1 _Pathology, Cedars Sinai Medical Center, Los Angeles, CA,_ 2 _Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA,_ 3 _Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, CA,_ 4 _Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA,_ 5 _Center for Surgical Device Management, Cedars Sinai Medical Center, Los Angeles, CA_

**(1357)** The Role of Beta Blockers in the Prevention of Gastrointestinal Bleeding After Left Ventricular Assist Device Implantation; __ R. Kaur, R. Singh, S. Phillips, K. Abdullah, S. S. Desai, P. Shah. _Heart Failure and Heart Transplant, Inova Heart and Vascular Hospital, Fairfax, VA_

**(1358)** Initiation of a Standardized International Normalized Ratio Management Protocol Reduces Out of Range Days in an Ambulatory LVAD Population; __ M. A. Thompson1, R. C. Jackson2, M. Frakes2, L. T. Hamann1, R. John3, R. J. Cogswell4. 1 _CV Specialty Nursing, University of MN Health, Minneapolis, MN,_ 2 _Fairview Pharmacy Services, University of MN Health, Minneapolis, MN,_ 3 _Cardiovascular Surgery, University of MN Health, Minneapolis, MN,_ 4 _Cardiology, University of MN Health, Minneapolis, MN_

**(1359)** Does Aspirin Effectively Inhibit Platelet Activation During Left Ventricular Assist Device Support?; __ F. Consolo1, L. Pozzi2, G. Motolone3, G. Sferrazza3, M. Pieri3, P. Della Valle2, A. Zangrillo1, M. J. Slepian4, A. D'Angelo2, F. Pappalardo1. 1 _Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Vita Salute University, Milano, Italy,_ 2 _Coagulation Service and Thrombosis Research Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy,_ 3 _Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milano, Italy,_ 4 _Department of Medicine and Biomedical Engineering, Sarver Heart Center, The University of Arizona, Tucson, AZ_

**(1360)** Incidence of Early Right Heart Failure After Left Ventricular Assist Device Implantation in Patients Managed without Inhaled Nitric Oxide; __ C. Michaud, G. Marco, A. Schaap, M. Dickinson, P. Wilton. _Spectrum Health, Grand Rapids, MI_

**(1361)** Incidence of High On-Treatment Platelet Reactivity in Continuous-Flow LVAD Patients Treated with P2Y12 Inhibitors; __ E. N. Sorensen1, L. Dees2, E. D. Feller2. 1 _Clinical Engineering, University of Maryland, Baltimore, MD,_ 2 _Cardiology, University of Maryland, Baltimore, MD_

**(1362)** Pre-Implant Digoxin Utilization and Impact on Survival in Left Ventricular Assist Device Recipients; __ M. Ahmed1, J. R. Trivedi2, E. J. Birks2, M. S. Slaughter3, H. Roukoz4, A. Bhan5, G. Bhat5, J. Cowger6, A. Ravichandran6, R. Gopinathannair2. 1 _Cardiovascular Medicine, Univeristy of Florida, Gainesville, FL,_ 2 _Cardiovascular Medicine, Univeristy of Louisville, Louisville, KY,_ 3 _Cardiovascular and Thoracic Surgery, Univeristy of Louisville, Louisville, KY,_ 4 _Cardiovascular Medicine, Univeristy of Minnesota, Minneapolis, MN,_ 5 _Advocate Christ Medical Center, Oak Lawn, IL,_ 6 _St Vincent Hospital, Indianapolis, IN_

**(1363)** Use of Abciximab and Heparin Can Safely Facilitate LVAD Implantation in Patients with Heparin-Induced Thrombocytopenia; __ C. Lee, P. C. Colombo, D. Jennings, J. Han, M. P. Salna, M. A. Wright, K. Takeda, P. A. Kurlansky, M. Yuzefpolskaya, A. R. Garan, C. Chan, Y. Naka, H. Takayama. _Columbia University Medical Center, New York City, NY_

## Pathology

(Harbor Foyer)

**Poster Discussants:** Anja C Roden, MD (USA), Carmela D Tan, MD (USA)

**(1364)** Is Vasculitis on Endomyocardial Biopsies a Marker of Circulating Donor Specific Antibodies in Adult Heart Transplanted Patients?; __ M. Fedrigo1, A. Romano1, A. Di Francesco1, C. Castellani1, A. Fraiese1, G. Toscano1, G. Feltrin1, A. Nocco2, E. Benazzi2, A. Veronesi3, G. Thiene1, G. Gerosa1, A. Angelini1. 1 _Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy,_ 2 _Fondazione IRCC S Cà Granda Ospedale Maggiore, Milano, Italy,_ 3 _Transfusion Medicine, Regional Laboratory of Transplant, Camposampiero Hospital, Camposampiero, Italy_

**(1365)** In Vivo Anti-MicroRNA Treatment in a Humanized Mouse Model for Allograft Vasculopathy; __ M. Huibers1, L. Qin2, G. Li2, J. Renes1, C. Venema1, E. Siera-de Koning1, J. van Kuik1, T. Peeters1, G. Tellides2, R. de Weger1. 1 _Pathology, UMC Utrecht, Utrecht, Netherlands,_ 2 _Surgery, Yale University, School of Medicine, New Haven, CT_

**(1366)** Ultrastructural Alterations in Explanted Failed Cardiac Allografts: Insights into "Chronic Rejection"; __ M. Revelo1, E. H. Hammond2, J. Stehlik3, R. Alharethi3, B. Reid4, S. Drakos3, C. Selzman4, K. Afshar3, O. Wever-Pinzon3, S. McKellar4, A. G. Kfoury5, D. V. Miller6. 1 _Pathology, Utah Cardiac Transplant Program, Salt Lake City, UT,_ 2 _Pathology, Utah Cardiac Transplant Program, Murray, UT,_ 3 _Cardiology, Utah Cardiac Transplant Program, Salt Lake City, UT,_ 4 _Surgery, Utah Cardiac Transplant Program, Salt Lake City, UT,_ 5 _Pathology, Intermountain Central Lab, Murray, UT,_ 6 _Intermountain Central Lab, Murray, UT_

**(1367)** Does Endomyocardial Biopsy (EMB) Contribute to Management of Patients with Myocardial Involvement in Autoimmune Disease?; __ D. Lee1, N. Narula2, K. Axsom3, M. Karas3, J. Gordon4, S. Seshan2, J. Kim3, E. Horn3, I. Sobol3. 1 _Department of Medicine, NYP-Weill Cornell Medical Center, New York, NY,_ 2 _Department of Pathology and Laboratory Medicine, NYP-Weill Cornell Medical Center, New York, NY,_ 3 _Division of Cardiology, NYP-Weill Cornell Medical Center, New York, NY,_ 4 _Department of Rheumatology, Hospital for Special Surgery, New York, NY_

**(1368)** Is Histopathological Assessment Going to Remain the Gold Standard for Diagnosis of Pulmonary Allograft Rejection?; __ K. Wassilew1, M. Perch2, E. Santoni Rugiu1. 1 _Pathology Department, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark,_ 2 _Department of Clinical Medicine- Hjertecentret, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark_

**(1369)** How to Improve the Survival of Future Transplant Recipients: An Autopsy Study; __ T. Hermida1, M. Delgado2, J. Pombo1, R. Fernández2, M. Escalante1, M. Paradela2, M. Haz1, E. Fieira2, P. Marcos3, J. Ovalle2, A. Reguera1, M. De La Torre2, A. Concha1. 1 _Pathology Department, A Coruña Universitary Hospital, A Coruña, Spain,_ 2 _Thoracic Surgery Department, A Coruña Universitary Hospital, A Coruña, Spain,_ 3 _Pneumology Department, A Coruña Universitary Hospital, A Coruña, Spain_

## Junior Faculty Clinical Case Reports

(Coronado Foyer)

**Poster Discussants:** Jorge Silva Enciso, MD (USA), Cameron R Wolfe, MBBS, MPH (USA), Jong-Chan Youn, MD, PhD (Korea)

**(1370)** Less Intense CPR for Right Ventricle Chest Compressions as a Paradigm for LVAD Patients Who Needing Resuscitation; __ A. Bhimaraj, J. D. Estep, E. E. Suarez. _Cardiology, Houston Methodist Hospital, Houston, TX_

**(1371)** Continuous Flow Implantable Biventricular Assist Device as Bridge to Transplantation in a Small Child with Restrictive Cardiomyopathy: Technical Pearls and Pitfalls; __ L. D. Glass1, O. Haddad2, A. Savage3, M. N. Kavarana2. 1 _Pediatric Cardiology, Stollery Children's Hospital, Edmonton, AB, Canada,_ 2 _Pediatric Cardiothoracic Surgery, Medical University of South Carolina, Charleston, SC,_ 3 _Pediatric Cardiology, Medical University of South Carolina, Charleston, SC_

**(1372)** Percutaneous Left Atrial Unloading for Prevention of Pulmonary Edema Under Extracorporeal Membrane Oxygenation Therapy; __ A. M. Bernhardt1, M. Hillebrand2, Y. Yildirim1, S. Hakmi1, F. M. Wagner1, S. Blankenberg2, H. Reichenspurner1, E. Lubos2. 1 _Department of Cardiovascular Surgery, Univ Heart Ctr Hamburg, Hamburg, Germany,_ 2 _Department of General and Interventional Cardiology, Univ Heart Ctr Hamburg, Hamburg, Germany_

**(1373)** A Case of Extrinsic Proximal Outflow Graft Compression Contributing to Elevated LDH in a Patient with Suspected Pump Thrombosis; __ N. Afari-Armah, S. Ahmed, F. Sheikh, S. Mohammed, S. Najjar, S. Boyce. _Advanced Heart Failure, Medstar Washington Hospital Center, Washington, DC_

**(1374)** Right Ventricular Failure Secondary to Apical Muscular VSD in an LVAD Patient; __ T. Suboc1, G. Murtaza2, G. Macaluso1, K. Meehan3, S. Pauwaa1, A. Andrade3, G. Bhat1, M. Bazavan1, A. Tatooles3, P. Pappas3, W. Cotts1. 1 _Advanced Heart Failure/VAD/Transplant, University of Illinois at Chicago/Advocate Christ Medical Center, Chicago, IL,_ 2 _Internal Medicine, University of Illinois at Chicago/Advocate Christ Medical Center, Chicago, IL,_ 3 _Advanced Heart Failure/VAD/Transplant, Advocate Christ Medical Center, Chicago, IL_

**(1375)** HeartMate 3 Inflow Pump Thrombosis; __ J. Eulert-Grehn, T. Krabatsch, S. Jacobs, V. Falk, E. Potapov. _Deutsches Herzzentrum Berlin, Berlin, Germany_

**(1376)** Candida albicans Mycotic Embolism in a LVAD Recipient; __ K. Kapoor1, P. Shah2, S. Desai2, C. W. May2, A. C. Carter2, S. Katugaha2. 1 _Virginia Commonwealth University School of Medicine, Inova Campus, Fairfax, VA,_ 2 _Inova Heart & Vascular Institute, Falls Church, VA_

**(1377)** The Cardiogenic Shock Protocol: A Model of Multidisciplinary, Advanced Heart Failure Driven Management at a Tertiary Care Center; __ V. A. Grewal, E. Khan, F. Katsikeris, A. Turk, S. Shaikh, J. Chou, G. Valania, M. T. Slawsky, D. Engelman, E. Lau, J. A. Hernandez-Montfort. _Internal Medicine, Baystate UMMS, Springfield, MA_

**(1378)** Concomitant Left Ventricular Assist Device Implantation and Aortic Valve Replacement Using a Rapid Deployment Valve Prosthesis as a Rescue Reoperation; __ M. Linder, E. Girdauskas, F. M. Wagner, A. Bernhardt, H. Reichenspurner, M. J. Barten. _Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany_

**(1379)** Tension Pneumopericardium in an LVAD, Rare but Real; __ H. Merritt Genore1, N. Markin2, A. Siddique1, J. Um1, M. Moulton1. 1 _Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE,_ 2 _Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE_

**(1380)** Acute Reversal of Chronic Cardiorenal Syndrome from Severe Tricuspid Regurgitation with Impella RP - A Novel Use of Percutaneous Mechanical Circulatory Support of the Right Ventricle; __ T. Raymond, R. Shah, A. Greenbaum. _Henry Ford Hospital, Detroit, MI_

**(1381)** Use of Venovenous Extracorporeal Membrane Oxygenation in Airway Obstruction as a Bridge to Rescue; __ V. Fikfak1, P. G. Khaitan2, E. E. Suarez3, M. P. Kim2, E. Y. Chan2. 1 _Department of Surgery, Houston Methodist Hospital, Houston, TX,_ 2 _Division of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, Houston, TX,_ 3 _Department of Cardiovascular Surgery, Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, TX_

**(1382)** A Case Study of LVAD Withdrawal in an Ambulatory Patient; __ S. Nakagawa1, P. C. Colombo2, Y. Naka3, C. D. Blinderman1. 1 _Adult Palliative Care Services, Department of Medicine, Columbia University Medical Center, New York, NY,_ 2 _Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY,_ 3 _Division of Cardiothoracic Surgery, Department of Surgery, Columbia University Medical Center, New York, NY_

**(1383)** Amplatzer Septal Occluder Placement For Management of Aortic Regurgitation After Left Ventricular Assist Device Implantation: Factors Influencing Patient Selection; __ V. Parikh, P. Gosain, D. Rinde-Hoffman, P. Berman. _Tampa General Hospital, Tampa, FL_

# ISHLT ACADEMY

## CORE COMPETENCIES IN INFECTIOUS DISEASES IN THORACIC

## TRANSPLANTATION AND MECHANICAL CIRCULATORY SUPPORT

Tuesday, April 4, 2017

Scientific Program Committee

Chair:  Martha Mooney, MD, FACP, Sentara Norfolk Transplant Center/Eastern Virginia Medical School, Norfolk, VA, USA

Co-Chair:  Shahid Husain, MD, MS, University Health Network, Toronto, ON, Canada

Members:  Michele Estabrook, MD, St. Louis Children's Hospital, St. Louis, MO, USA

Robin Avery, MD, Johns Hopkins University, Baltimore, MD, USA

Kate Gould, FRCPath, NUTH NHS Foundation Trust, Newcastle Upon Tyne, United Kingdom

Orla Morrissey, MD, The Alfred Hospital, Melbourne, Australia

Target Audience

While all members are invited to enroll, this course is primarily designed to be of benefit for clinicians and allied professionals who are in the early stages of their careers or who are in training and/or are part of a new program or desire an update on the current state of the field. The information presented covers core competencies and is intended to provide a strong foundation of the overarching principles of infectious disease concerns in cardiothoracic transplantation and mechanical circulatory support, rather than as a detailed update for those who are already proficient experts in the field.

Learning Objectives

At the conclusion of this meeting, participants will have improved competence and professional performance in their ability to:

  * Explain how to utilize pre-transplant evaluation and screening of the cardiothoracic transplant recipient and donor to minimize the risk of infections in cardiothoracic transplant and MCS recipients
  * Describe how to control and prevent infection in cardiothoracic transplantation and MCS recipients 
  * Identify clinical infections and how to use diagnostic methodology for the detection of bacterial, fungal, viral, and parasitic infectious diseases 
  * Discuss the pharmacology of anti-infective agents in cardiothoracic transplant and MCS recipients.

Accreditation Statement

The International Society for Heart and Lung Transplantation (ISHLT) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation Statement

ISHLT designates this live activity for a maximum of 7.75 _AMA PRA Category 1 Credits_ ™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

**ANCC Credit  
** AMEDCO is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

This course is co-provided by AMEDCO and ISHLT. Maximum of 7.75 contact hours.

Disclosure

Current guidelines state that participants in CME activities must be made aware of any affiliation or financial interest that may affect the program content or a speaker's presentation. Planners, Faculty and Chairs participating in this meeting are required to disclose to the program audience any real or apparent conflict(s) of interest related to the content of their presentations or service as Chair/Planner. These disclosures will be distributed at the meeting. Additionally, all speakers have been asked to verbally disclose at the start of their presentation if a product they are discussing is not labeled for the use under discussion or is still investigational.
SCIENTIFIC PROGRAM SCHEDULE

7:00 AM – 7:45 AM

REGISTRATION & MORNING COFFEE

7:45 AM – 8:00 AM  
WELCOME & OVERVIEW

Martha Mooney, MD, FACP, Sentara Norfolk Transplant Center/EVMS, Norfolk, VA, USA

Shahid Husain, MD, MS, University Health Network, Toronto, ON, Canada

**8:00 AM – 9:20 AM**

SESSION 1: IMPACT OF SURGERY AND IMMUNOSUPPRESSION ON INFECTION IN CT TX RECIPIENT AND DONOR SELECTION CONSIDERATIONS

**8:00 AM** Impact of the Surgical Transplant Procedure on Infection Risk in CT TX

Andreas Zuckermann, MD, Medical University of Vienna, Vienna, Austria

**8:15 AM** The Devil Made Me Do It: Impact of Immunosuppression on Infection Risk in CT TX

Shahid Husain, MD, MS, University Health Network, Toronto, ON, Canada

**8:30 AM** Not All Transplant Recipients are Created Equal! Pre-transplant Screening of Recipients

Michele Estabrook, MD, St. Louis Children's Hospital, St. Louis, MO, USA

**8:50 AM** Beware the Trojan Horse: Pre-transplant Screening of Donors and Donor Derived Infections

Valentina Stosor, MD, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

9:10 AM Q & A

9:20 AM – 10:20 AM  
SESSION 2: DIAGNOSING INFECTION IN CT TX AND TREATMENT CONSIDERATIONS

**9:20 AM** Diagnostic Microbiology and Pathology for Infections in CT TX

Kate Gould, FRCPath, Freeman Hospital, Newcastle Upon Tyne, United Kingdom

**9:40 AM** Diagnostic Radiology for Infections in CT TX

Allan Glanville, MBBS, MD, FRACP, St. Vincent's Hospital, Sydney, Australia

**9:55 AM** This Could Happen to You...Drug Interactions and Toxicity Errors to Avoid with Anti-infectives and Immunosuppression and Cracking the Therapeutic Drug Monitoring Code

Christopher Ensor, PharmD, BCPS-CV, University of Pittsburgh, Pittsburgh, PA, USA

10:15 AM Q & A

10:20 AM – 10:35 AM

COFFEE BREAK
10:35 AM – 11:35 AM  
SESSION 3: BACTERIAL AND PARASITIC PATHOGENS

**10:35 AM** __ Nosocomial Threats and Tackling Multidrug Resistant Bacteria: If We Persist, We Will Wear Down the Resistance!

Kate Gould, FRCPath, Freeman Hospital, Newcastle Upon Tyne, United Kingdom

**10:55 AM** Bugs that Upset Us and Send Us into Orbit: Mycobacteria and Nocardia

Orla Morrissey, MD, The Alfred Hospital, Melbourne, Australia

**11:10 AM** Unwelcome Visitors: Parasitic Infections in CT TX: Toxoplasmosis, Strongyloidiasis, Chagas

Fernando Bacal, MD, University of Sao Paulo, Sao Paulo, Brazil

11:25 AM Q & A

11:35 AM – 12:45 PM

SESSION 4: VIRAL INFECTIONS IN CT TX

**11:35 AM** CMV: a Perennial Problem

Martha Mooney, MD, FACP, Sentara Norfolk Transplant Center/EVMS, Norfolk, VA, USA

**11:50 AM** EBV/PTLD: a Continual Conundrum

Erik Verschuuren, MD, PhD, University Medical Centre Groningen, Groningen, The Netherlands

**12:05 PM** Challenges from the Community: Respiratory Viruses, Parvovirus, Norovirus and Others

Joanna Schaenman, MD, PhD, University of California Los Angeles, Los Angeles, CA, USA

**12:20 PM** HIV, HCV, HBV: Risks Redefined?

Emily Blumberg, MD, University of Pennsylvania, Philadelphia, PA, USA

12:40 PM Q & A

12:45 PM - 1:45 PM

**LUNCH BREAK** (a box lunch is included in the registration fee)

1:45 PM – 2:55 PM  
SESSION 5: FUNGAL INFECTIONS AND OTHER AREAS OF CONCERN FOR TRAVEL AND SAFE LIVING AFTER CT TX

**1:45 PM** There is a Fungus Among Us. Perils from Without: Mold, Yeast, and Guidelines

Shahid Husain, MD, MS, University Health Network, Toronto, ON, Canada

**2:05 PM** Perils from Within: Endemic Fungi

Me-Linh Luong, MD, St. Luc Hospital, Montreal, PQ, Canada

**2:20 PM** Emerging Fungal Pathogens

Orla Morrissey, MD, The Alfred Hospital, Melbourne, Australia

**2:35 PM** Life in the Global Community after Transplant: Travel, Safe Living and Emerging Pathogens. Real Risks Outside the Bubble: Roaming Charges

Michele Estabrook, MD, St. Louis Children's Hospital, St. Louis, MO, USA

2:50 PM Q & A

2:55 PM - 3:10 PM

COFFEE BREAK

3:10 PM – 4:10 PM

SESSION 6: INFECTION IN THE SETTING OF MECHANICAL CIRCULATORY SUPPORT (MCS)

**3:10 PM** An Ounce of Prevention Saves a Pound of Hurt: Prevention and Diagnosis of Infections in MCS

Saima Aslam, MD, MS, University of California San Diego, San Diego, CA, USA

**3:25 PM** VAD Gone Bad: Medical and Surgical Remedies of VAD Specific and VAD Related Infections

Martha Mooney, MD, FACP, Sentara Norfolk Transplant Center/EVMS, Norfolk, VA, USA

**3:45** PM Hungry Circuits in Extracorporeal Support (ECMO, Plasmapheresis, Renal Replacement Therapy) and Steering Clear of Anticoagulation Glitches with Antibiotics in Mechanical Circulatory Support

Haifa Lyster, MSc, Royal Brompton, Middlesex, United Kingdom

4:00 PM Q & A

4:10 PM – 5:00 PM

SESSION 7: WHEN THE RUBBER HITS THE ROAD: CASE PRESENTATIONS

**4:10 PM** CASE 1: HIV/HBV/HCV in Cardiothoracic Transplantation

Emily Blumberg, MD, University of Pennsylvania, Philadelphia, PA, USA

**4:30 PM** CASE 2: Lung Transplant Recipient with Pulmonary Infiltrates: Transplant Infectious Disease Consults Transplant Pulmonologist to Make the Diagnosis

Aric Gregson, MD, University of California Los Angeles School of Medicine, Los Angeles, CA, USA

Allan Glanville, MBBS, MD, FRACP, St. Vincent's Hospital, Sydney, Australia

4:50 PM Q & A

5:00 PM – 5:15 PM

COURSE SUMMARY & EVALUATION

Martha Mooney, MD, FACP, Sentara Norfolk Transplant Center/EVMS, Norfolk, VA, USA

Shahid Husain, MD, MS, University Health Network, Toronto, ON, Canada

5:15 PM

ADJOURN

# ISHLT ACADEMY

## CORE COMPETENCIES IN MECHANICAL CIRCULATORY SUPPORT

Tuesday, April 4, 2017

Scientific Program Committee

Chair:  Jennifer Cowger, MD, MS, St. Vincent Heart Center of Indiana, Indianapolis, Indiana, USA

Co-Chair:  Palak Shah, MD, MS, Inova Heart and Vascular Institute, Falls Church, Virginia, USA

Co-Chair:  Diyar Saeed, MD, Heinrich-Heine University, Dusseldorf, Germany

Educational Goals

The educational goals of this activity are to provide a concise review of clinical knowledge and essential professional skills to facilitate best practice of surgical and medical aspects involved in the care of patients during assessment as candidates and as recipients of mechanical circulatory support.

Target Audience

While all members are invited to enroll, this course is primarily designed to be of benefit for clinicians and allied professionals who are in the early stages of their careers or who are in training and/or are part of a new program or desire an update on the current state of the field. The information presented covers core competencies and is intended to provide a strong foundation of the overarching principles of mechanical support, rather than as a detailed update for those who are already proficient experts in the field.

Learning Objectives

At the conclusion of this meeting, participants will have improved competence and professional performance in their ability to:

  1. Explain how to risk stratify patient with advanced heart failure in order to assess MCS surgical risk and optimally time mechanical circulatory support (MCS) implantation.
  2. Discuss the medical and social factors which impact patient outcomes during short- and long-term MCS.
  3. Recognize the various types of MCS support available for patients with advanced single or biventricular heart failure and the technological differences that may impact pump selection and patient/device management.
  4. Identify MCS implantation techniques and patient/pump management during the index admission intensive care unit and inpatient general care periods.
  5. Describe how to manage patients and the MCS during outpatient long-term support with an understanding of interventions that can reduce patient- and device-related adverse events during MCS.
  6. Diagnose and manage common clinical dilemmas and adverse encountered after MCS.

Accreditation Statement

The International Society for Heart and Lung Transplantation (ISHLT) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation Statement

ISHLT designates this live activity for a maximum of 8.00 _AMA PRA Category 1 Credits_ ™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

**ANCC Credit  
** AMEDCO is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

This course is co-provided by AMEDCO and ISHLT. Maximum of 8.00 contact hours.

Disclosure

Current guidelines state that participants in CME activities must be made aware of any affiliation or financial interest that may affect the program content or a speaker's presentation. Planners, Faculty and Chairs participating in this meeting are required to disclose to the program audience any real or apparent conflict(s) of interest related to the content of their presentations or service as Chair/Planner. These disclosures will be distributed at the meeting. Additionally, all speakers have been asked to verbally disclose at the start of their presentation if a product they are discussing is not labeled for the use under discussion or is still investigational.
SCIENTIFIC PROGRAM SCHEDULE

7:00 AM – 8:00 AM

REGISTRATION & MORNING COFFEE

8:00 AM – 8:05 AM

WELCOME AND OVERVIEW

Jennifer Cowger, MD, MS, St. Vincent Heart Center of Indiana, Indianapolis, IN, USA

8:05 AM - 9:15 AM

SESSION 1 – REVIEW OF THE CURRENT STATE OF MCS

**Chair:** Diyar Saeed, MD

**8:05 AM** MCS Technology 101

Scott Silvestry, MD, Florida Transplant Institute, Orlando, FL, USA

_Review of current technologies available, pump behaviors with different loading conditions, and the TAH._

**8:25 AM** BTT and DT Outcomes

Lynne Warner Stevenson, MD, Brigham & Women's Hospital, Boston, MA, USA

Review state of outcomes and adverse events with current technologies

**8:40 AM** Short-term Support and Shock

Jonathan Haft, MD, University of Michigan, Ann Arbor, MI, USA

Overview of percutaneous technologies, biventricular support considerations, and ECMO.

9:00 AM Q&A with Panel

9:15 AM – 10:30 AM

SESSION 2 – PATIENT SELECTION

**Chair:** Scott Silvestry, MD

**9:15 AM** When Should Patients be Referred: Warning Signs

Douglas Horstmanshoff, MD, Integris Baptist Medical Center, Oklahoma City, OK, USA

Risk factors which presage patient decline (renal function, intolerance of medications, hospitalizations, etc, helping to risk stratify patients based on HF severity and MCS operative risk.

**9:35 AM** Assessing and Optimizing RV Function Preoperatively

Jerry Estep, MD, The Methodist Hospital, Houston, TX, USA

Impact of RV failure, pre-operative assessment and management of the RV including imaging and risk prediction. Cases included.

**9:55 AM** Quality of Life After VAD and the Impact of Frailty and Social Behaviors on VAD Success

Kathleen Grady, PhD, APN, FAAN, Northwestern Memorial Hospital, Chicago, IL, USA

Other factors that can have a significant impact on success after VAD and some screening tools available for risk assessment.

10:15 AM Q&A with Panel

10:30 AM – 10:45 AM

COFFEE BREAK

10:45 AM – NOON

SESSION 3 – SURGICAL CONSIDERATIONS

**Chair:** Vivek Rao, MD, PhD

**10:45 AM** Key Surgical Aspects of Implantation

Nader Moazami, MD, Cleveland Clinic, Cleveland, OH, USA

Overview of the most crucial surgical considerations: inflow cannula/pump placement, driveline, etc.

**11:05 AM** How Much Else is Too Much? ****

Daniel Zimpfer, MD, Medical University of Vienna, Vienna, Austria

Concomitant operative procedures: TV, Aortic valve, prior Dor, congenitals

**11:25 AM** Tailoring Pumps to Patients

Diyar Saeed, MD, Heinrich-Heine University, Dusseldorf, Germany

Case based discussion of considerations for pump-patient matching

11:45 AM Q&A with Panel

NOON – 1:00 PM

**LUNCH BREAK** (a box lunch is included in the registration fee)

1:00 PM – 2:15 PM

SESSION 4 – POSTOPERATIVE CARE

**Chair:** Andreas Zuckerman, MD

**1:00 PM** Managing the RV Postop

Christopher Salerno, MD, St Vincent Heart Center of Indiana, Indianapolis, Indiana, USA

Considerations for impact of LVAD pump speed on RV function and use of inotropes, pulmonary vasodilators, and temporary RV support postoperatively

**1:20 PM** Anticoagulation and Antiplatelet Therapy

Vivek Rao, MD, PhD, Toronto General Hospital, Toronto, ON, Canada

Current MCS recommendation on when to start anticoagulation, antiplatelet therapy regimens, as well as data on platelet function testing and heparin level monitoring.

**1:40 PM** Pump Speed Optimization: The Role of Imaging and Hemodynamics **  
**Jerry Estep, MD, Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA  
 _Overview of how to meld imaging and hemodynamics to optimize pump settings_

2:00 PM Q&A with Panel

2:15-3:15 PM

SESSION 5 – TRANSITION TO HOME

**Chair:** Nir Uriel, MD

**2:15 PM** VAD Education: Patient/Caregiver Assessments and Strategies for Successful VAD Self-Care

Thomas Schlöglhofer, BSc, Medical University of Vienna, Vienna, Austria

Approaches to education of the patient and caregiver prior to discharge, and strategies for educating the local medical community

**2:30 PM** Starting New: How to Start and Succeed in MCS

Michael Dickinson, MD, Spectrum Health, Grand Rapids, MI, USA

Challenges to starting a VAD program and key elements of success.

**2:45 PM** Optimal Outpatient Management of VAD Recipients

Jennifer Cowger, MD, MS, St. Vincent Heart Center of Indiana, Indianapolis, IN, USA __

Lab, blood pressure and echo monitoring of VAD patients in the outpatient setting.

3:00 PM Q&A with Panel

3:15 PM - 3:30 PM

COFFEE BREAK

3:30 PM - 5:20 PM

SESSION 6 – LONG TERM MANAGEMENT OF PATIENTS AND COMPLICATIONS

**Chair:** Nader Moazami, MD

**3:30 PM** LVAD Infections: Prevention, Diagnosis, and Management

Paolo A Grossi, MD, PhD, University of Insubria, Varese, Italy

VAD infections, radiology studies important for diagnosis, and therapeutic recommendations

**3:50 PM** Stroke: Risk Factors for Hemorrhagic and Embolic CNS Complications and Management Strategies  
Samer Najjar MD, MedStar Washington Hospital Center, Washington, DC, USA  
 _Discuss diagnosis, risk factors, and management strategies for CNS events in MCS patients._

**4:10 PM** Pump Thrombosis: __ Diagnostic Strategies and Management Algorithms

Palak Shah, MD, MS, Inova Heart and Vascular Institute, Falls Church, VA, USA

Frequency, diagnosis, and management strategies for suspected pump thrombosis.

**4:30 PM** Aortic Insufficiency in LVAD Recipients _:_ Incidence, Screening, and Management

Jennifer Cowger, MD, MS, St Vincent Heart Center of Indiana, Indianapolis, IN, USA

Cumulative incidence, clinical consequences, and management of AI after LVAD.

**4:50 PM** GI Bleeding

Anna Meyer, MD, Leipzig University Heart Center, Leipzig, Germany

_Frequency, diagnosis and management of GI bleeding after LVAD therapy, including new data on octreotide_

5:10 PM Q&A with Panel

**5:20 PM S** **UMMARY**

Palak Shah, MD, MS, Inova Heart and Vascular Institute, Falls Church, VA, USA

5:30 PM ADJORN

# CORE COMPETENCIES IN

## PEDIATRIC AND ADULT CONGENITAL

## MECHANICAL CIRCULATORY SUPPORT

Tuesday, April 4, 2017

Scientific Program Committee

Chair:  Angela Lorts, MD, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA

Co-Chair:  Holger Buchholz, MD, University of Alberta, Stollery Children's Hospital, Edmonton, AB, Canada

Members:  Jenna Murray, MSN, RN, CPNP-AC, Stanford University, Stanford, California, USA

Leonardo Salazar, MD, Fundacion Cardiovascular de Columbia, Bucaramanga, Columbia

Martin Schweiger, MD, PhD, FEBS Children's Hospital Zurich, Zurich Switzerland

Asif Hasan, MB, FRCS, Freeman Hospital, Newcastle Upon Tyne, United Kingdom

Course Summary

The pediatric mechanical circulatory support field continues to grow and has enough unique challenges to justify an entire session dedicated to learning about pediatric support strategies. The basic principles of MCS, including patient/device selection, peri-operative management, and basics of transition to home will be discussed. The goal will be to learn from didactics but also allow for discussion in order to share experiences and learn from each other.

In addition to the core academy that will be conducted at the 2017 ISHLT annual meeting, an extensive Core Competency Curriculum Document has been written by a diverse international committee and can be found on the ISHLT education website. This document is in outline form with current references and includes all topics that are important to the management of this unique patient population.

Educational Goals

The educational goals of this activity are to provide a concise review of clinical knowledge and essential professional skills to facilitate best practice of surgical and medical aspects involved in the care of pediatric patients and adult congenital heart disease patients that require ventricular assist device support.

Target Audience

While all members are invited to enroll, this course is primarily designed to be of benefit for clinicians and allied professionals who are in the early stages of their careers or who are in training, are part of a new program or desire an update on the current state of the field. The information presented is intended to provide a strong foundation of the overarching principles of ventricular assist support in children, rather than as a detailed update for those who are already proficient in the field.

Learning Objectives

At the conclusion of this meeting, participants will have improved competence and professional performance in their ability to:

  1. Evaluate a patient for VAD implantation including preoperative assessment, preparation of patient prior to VAD implantation, and optimal timing of placement.
  2. Understand device selection, strategies for VAD implantation, intraoperative assessment techniques and postoperative management. 
  3. Define device-specific anticoagulation management as well as the recognition and care of adverse events related to both temporary and chronic device therapy.

Accreditation Statement

The International Society for Heart and Lung Transplantation (ISHLT) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation Statement

ISHLT designates this live activity for a maximum of 8.00 _AMA PRA Category 1 Credits_ ™ Physicians should claim only the credit commensurate with the extent of their participation in the activity.

**ANCC Credit  
** AMEDCO is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

This course is co-provided by AMEDCO and ISHLT. Maximum of 8.00 contact hours.

Disclosure

Current guidelines state that participants in CME activities must be made aware of any affiliation or financial interest that may affect the program content or a speaker's presentation. Planners, Faculty and Chairs participating in this meeting are required to disclose to the program audience any real or apparent conflict(s) of interest related to the content of their presentations or service as Chair/Planner. These disclosures will be distributed at the meeting. Additionally, all speakers have been asked to verbally disclose at the start of their presentation if a product they are discussing is not labeled for the use under discussion or is still investigational.
SCIENTIFIC PROGRAM SCHEDULE

7:00 AM – 7:45 AM

REGISTRATION & MORNING COFFEE

7:45 AM – 8:00 AM

WELCOME AND OVERVIEW

Angela Lorts, MD, Cincinnati Children's Hospital, Cincinnati, OH, USA

Holger Buchholz, MD, University of Alberta Hospital, Edmonton, AB, Canada

8:00 AM – 9:05 AM

SESSION 1: REVIEW OF THE CURRENT STATE OF MCS IN PEDIATRIC AND ADULT CONGENITAL HEART DISEASE

**Chair:** Richard Kirk, FRCP, FRCPCH

**8:00 AM** Current State: Durable Device Options, Indications and Outcomes (Pulsatile)

David Morales, MD, Cincinnati Children's Hospital, Cincinnati, OH, USA

_A review of current technologies available, update on future developments_ **.**

**8:15 AM** Current State: Durable Device Options, Indications and Outcomes (Continuous) ****

Martin Schweiger, MD, PhD, Children's Hospital, Zurich, Switzerland

_Overview of MCS in ACHD patients_.

**8:30** **AM** Current State: Temporary Device __ Options, Indications and Outcomes

Jennifer Conway, MD, Stollery Children's Hospital, Edmonton, AB, Canada

Overview of temporary support in variety of scenarios as bridge to other forms of support, transplantation or recovery.

**8:45 AM** Case Presentation with Discussion: Child Presenting with Probable Myocarditis – Device Selection for Size and Indication

Leonardo Salazar, MD, Fundacion Cardiovascular de Colombia, Bucaramanga, Colombia

9:05 AM – 10:10 AM

SESSION 2: PATIENT SELECTION

**Chair:** Angela Lorts, MD

**9:05 AM** An Art, Not Always a Science - When is the Right Time for Referral?

Aamir Jeewa, MD, Hospital for Sick Children, Toronto, ON, Canada

Evaluating timing for implantation.

**9:20 AM** Pre-VAD Work Up Prior to Implantation; Including Psychosocial Considerations

Oliver Miera, MD, Deutsches Herzzentrum Berlin, Berlin, Germany

Pre-VAD evaluation to be done prior to decision to implant.

**9:35 AM** Medical Co-Morbidities and That May VAD Success and Potential Strategies for Optimization ****

Janet Scheel, MD, Children's National Health System, Washington, DC, USA

End-organ dysfunction and the effect on VAD patient outcome.

**9:50 AM** Case Presentation with Discussion: Infant with End-Organ Dysfunction- Patient Selection and Optimization Prior to VAD Implantation

Richard Kirk, FRCP, FRCPCH, UT Southwestern Medical Center, Dallas, TX, USA

10:10 AM – 10:30 AM

COFFEE BREAK

10:30 AM – 11:20 AM

SESSION 3: SURGICAL CONSIDERATIONS FOR BOTH PEDIATRICS AND ADULT CONGENITAL

**Chair:** Martin Schweiger, MD, PhD

**10:30 AM** VAD Implantation (Extracorporeal Berlin Heart, Temporary Continuous Flow Devices): Key Surgical Aspects

Jake Jaquiss, MD, Duke Children's Heart Center, Durham, NC, USA

Key surgical techniques to implanting pulsatile devices in children.

**10:45 AM** VAD Implantation (Intracorporeal HVAD, HeartMate II): Key Surgical Aspects

Antonio Amodeo, MD, Bambino Gesu Pediatric Hospital, Rome, Italy

Key surgical techniques to implanting continuous flow devices in children

**11:00 AM** Case Presentation with Discussion: Assessment of Optimal Inflow Placement with Hemodynamics and Echocardiography in the Immediate Peri-Operative Setting

Lucas Eastaugh, MBBS, Royal Children's Hospital, Melbourne, Australia

11:20 AM – 12:00 PM

SESSION 4: "UNIQUE PATIENT POPULATION"

**Chair:** Jennifer Conway, MD

**11:20 AM** Case Presentation with Discussion: Adult Congenital VAD Case

Robert Jaquiss, MD, Duke Children's Heart Center, Durham, NC, USA

**11:40 AM** Case Presentation with Discussion: Adolescent Risky Behavior

Jenna Murray, MSN, RN, CPNP-AC, Lucile Packard Children's Hospital, Palo Alto, CA, USA

12:00 PM - 1:00 PM

**LUNCH BREAK** (a box lunch is included in the registration fee)

1:00 PM - 2:05 PM

SESSION 5: PERI-OPERATIVE CARE OF THE VAD PATIENT

**Chair:** Leonardo Salazar, MD __

**1:00 PM** Managing the RV after LVAD Placement

Richard Kirk, FRCP, FRCPCH, UT Southwestern Medical Center, Dallas, TX, USA

How to detect RV failure and to support the RV to prevent a Bi-VAD.

**1:15 PM** Is There a "Standard" for Post-Operative Care? ****

Angela Lorts, MD, Cincinnati Children's Hospital, Cincinnati, OH, USA

Routine post-operative care of the VAD patient in both the ICU and step down unit.
**1:30 PM** Pump Speed Optimization: Tailoring Post-Operative Management to Clinical and Echocardiographic Assessment

Lucas Eastaugh, MBBS, Royal Children's Hospital, Melbourne, Australia

Using hemodynamic monitoring to optimize the pump function.

**1:45 PM** Case Presentation with Discussion: Driveline Infection ****

Holger Buchholz, MD, University of Alberta Hospital, Edmonton, AB, Canada

2:05 PM – 3:10 PM

SESSION 6: HEMATOLOGIC MANAGEMENT OF THE PEDIATRIC VAD PATIENT

**Chair:** Holger Buchholz, MD

**2:05 PM** Overview of Anticoagulation of the Various Pump Types

Christina Vanderpluym, MD, Boston Children's Hospital, Boston, MA, USA

Brief overview of anticoagulation goals for various pump types and how the goals differ between adults and children.

**2:20 PM** Pump Thrombosis: Detection and Management

Jennifer Conway, MD, Stollery Children's Hospital, Edmonton, AB, Canada

How to determine if a pump is thrombosed and treatment options.

**2:35 PM** Stroke in Pediatric VAD Patients: What are Our Options?

Oliver Miera, MD, Deutsches Herzzentrum Berlin, Berlin, Germany

Characterizing pediatric strokes and discussing changes in therapy after they occur.

**2:50 PM** Case Presentation with Discussion: Tamponade Post HVAD Implantation

David Morales, MD, Cincinnati Children's Hospital, Cincinnati, OH, USA

3:10 PM -3:30 PM COFFEE BREAK

3:30 PM – 5:00 PM

SESSION 7: NOW WE ARE GOING TO SEND THEM HOME?

**Chair:** Antonio Amodeo, MD

**3:30 PM** The Beginning of a New Program: Necessary Team Components?

Christina Vanderpluym, MD, Boston Children's Hospital, Boston, MA, USA

The building blocks to starting a pediatric VAD program, the challenges faced, and the key elements of success.

**3:45 PM** Preparing the Patient, Family and Community for Discharge

Jenna Murray, MSN, RN, CPNP-AC, Lucile Packard Children's Hospital, Paolo Alto, CA, USA

Creative multidisciplinary approaches to patient/caregiver education and comprehensive preparation for the local community.

**4:00 PM** The Outpatient Clinical Assessment: Blood Pressure, Laboratory Testing, Echo Monitoring and Rehabilitation

Aamir Jeewa, MD, Hospital for Sick Children, Toronto, ON, Canada

Effective clinical assessment and monitoring strategies of the child outpatient on VAD support. 
**4:15 PM** Destination/Palliative Care Considerations

Janet Scheel, MD, Children's National Health System, Washington, DC, USA

Challenges in offering destination therapy to a child and how to maneuver failed VAD support.

4:30 - 5:00 PM

QUESTIONS/DISCUSSION

Panel members will reflect on day and open up for discussion

5:00 PM – 5:15 PM

CLOSING ADDRESS

Angela Lorts, MD, Cincinnati Children's Hospital, Cincinnati, OH, USA

Holger Buchholz, MD, University of Alberta Hospital, Edmonton, AB, Canada

5:15 PM ADJOURN

# ISHLT MASTER CLASS IN

## MECHANICAL CIRCULATORY SUPPORT

Tuesday, April 4, 2017

Scientific Program Committee

Chair:  Stavros Drakos, MD, PhD, University of Utah School of Medicine, Salt Lake City, UT, USA

Co-Chair:  Ivan Netuka, MD, PhD, Institute for Clinical and Experimental Medicine, Prague, Czech Republic **  
**

Members: Keith Aaronson, MD, University of Michigan, Ann Arbor, Michigan, USA

Anson Cheung, MD, University of British Columbia, Vancouver, BC, Canada

Chris Hayward, MD, St. Vincent's Hospital, Sydney, Australia

Lars Lund, MD, Karolinska Institute, Stockholm, Sweden

Course Summary

The MCS Master Class is intended for members with higher levels of expertise (completed the core curriculum course on MCS and/or primary practice in MCS ≥ 5 years). The course setting will generate a highly interactive environment composed of a small group of individuals and designed to enhance individual expertise and network development. Utilizing the concept of "convergent discussion" and the technique of "audience response system", faculty moderators will use complex situations and controversial statements during practical case presentations in order to lead the group through active audience participation, towards specific answers based on practice gaps and learning objectives. The MCS Master Class is arranged in advanced breakout sessions for every participant to take full advantage of an integrated curriculum and the exceptional networking opportunity. The specific topics are devised according to defined clinical practice gaps in this fast developing specialty.

Practice Gaps

**1:** The outcomes of cardiogenic shock have remained poor, large randomized trials are scarce and the management of these patients remains challenging. Comprehensive clinical expertise of advanced usage of evolving MCS options including patient and device selection and transition to next step therapies constitute currently major limitations in the care of these critically ill patients.

**2:** Specific approaches to optimize the exercise capacity of MCS patients is an unmet clinical need.

**3:** The disparities in the cardiac recovery outcomes observed between various centers indicate that implementing targeted patient selection and subsequently effective diagnostic and therapeutic protocols to facilitate cardiac recovery is challenging for the majority of practitioners.

**4:** The diagnosis and management of complex and combined adverse events such as cerebrovascular hemorrhagic accidents, device thrombosis and gastrointestinal bleeding is challenging and practitioners often face difficulties in developing effective strategies to appropriately identify and treat these adverse events.

**5:** The diagnostic and therapeutic approaches for early and late right ventricular failure in MCS patients has been evolving with the introduction of new diagnostic criteria and new technologies/therapeutic options. Such practice gaps in specialist knowledge and clinical skills constitute major limitations in the care of MCS patients.

**6:** With the rapid evolution of minimally invasive surgical approaches the individual practitioners may lack the extensive expertise required to appropriately select patients and surgical approaches to achieve the best possible outcome.

Educational Goals

The overarching goal is to provide an advanced learning opportunity for specialists and developing experts in the field of MCS and devices for treatment of heart failure patients.

Target Audience

The target audience for this class includes cardiothoracic surgeons and cardiologists with MCS experience, specialists in heart failure care, allied health professionals with involvement in MCS patients, VAD coordinators, transplant coordinators, critical care specialists, and heart transplant professionals.

Learning Objectives

Upon completion of the Master Class, participants will be able to:

1: Identify the challenges during the diagnosis and management of complex cardiogenic shock patients and the potential benefits of a multidisciplinary team approach.

2: List effective strategies to optimize exercise capacity and facilitate myocardial recovery in MCS patients.

3: Explain how to appropriately select patients for long-term MCS options with particular consideration in anticipated surgical management aspects.

4: Describe how to develop a systematic approach to diagnosis and therapy of complex and combined adverse events such as device thrombosis, recurrent gastrointestinal bleeding and stroke.

5: Name the diagnostic and therapeutic challenges of early and late RV failure.

Accreditation Statement

The International Society for Heart and Lung Transplantation (ISHLT) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation Statement

ISHLT designates this live activity for a maximum of 4.25 _AMA PRA Category 1 Credits_.™ Physicians should claim only the credit commensurate with the extent of their participation in the activity.

ANCC Credit

AMEDCO is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

This course is co-provided by AMEDCO and ISHLT. Maximum of 4.25 contact hours.

Disclosure

Current guidelines state that participants in CME activities must be made aware of any affiliation or financial interest that may affect the program content or a speaker's presentation. Planners, Faculty and Chairs participating in this meeting are required to disclose to the program audience any real or apparent conflict(s) of interest related to the content of their presentations or service as Chair/Planner. Please refer to the Participant Notification document for a list of all disclosures. Additionally, all speakers have been asked to verbally disclose at the start of their presentation if a product they are discussing is not labeled for the use under discussion or is still investigational.
SCIENTIFIC PROGRAM SCHEDULE

7:00 AM – 7:45 AM

REGISTRATION AND MORNING COFFEE

**7:45 AM – 8:00 AM  
WELCOME AND INTRODUCTIONS   
**Stavros Drakos, MD, PhD, University of Utah School of Medicine, Salt Lake City, UT, USA

8:00 AM – 9:00 AM

SMALL GROUP INTERACTIVE DISCUSSION A: ACUTE MCS FOR PROFOUND CARDIOGENIC SHOCK/INTERMACS 0-1 PROFILES

**Moderator:** **** Stavros Drakos, MD, PhD

8:00 AM

CASE SCENARIO: Management Challenges for 'Crash and Burn' Patients: 'Shock Team' Approach to MCS

Hiroo Takayama, MD, Columbia University, New York, NY, USA

Teaching/Discussion Points

  1. Challenges of assessing patients in profound cardiogenic shock: 
    1. Lack of universally accepted classification system of cardiogenic shock and its influence on patient management
    2. Important factors to consider at initial evaluation
  2. Challenges in choosing the appropriate timing for MCS
  3. Challenges in choosing the appropriate MCS device 
    1. Theoretical advantages/disadvantages of each device
    2. Existing clinical evidence
  4. SHOCK team approach to cardiogenic shock: patient benefits and logistical difficulties
  5. Initial attempts in developing an algorithm for MCS therapy for cariogenic shock

8:30 AM

CASE SCENARIO: Transition from Short to Long-Term Support

Keith Aaronson, MD, University of Michigan, Ann Arbor, MI, USA

Teaching/Discussion Points

  1. When is the optimal time to transition from temporary to durable MCS?
  2. How should you I assess and prioritize end organ function in the decision to proceed with durable MCS?
  3. How does temporary MCS affect the risk of RV failure post durable VAD?
  4. What are the other considerations when bridging from temporary to durable MCS?

9:00 AM – 9:05 AM

Speakers switch rooms; delegates remain seated

9:05 AM – 10:05 AM

**SMALL GROUP INTERACTIVE DISCUSSION B:** **COMPLEX COAGULATION ISSUES IN MCS PATIENTS**

**Moderator:** Ivan Netuka, MD, PhD

9:05 AM

CASE SCENARIO: Recurrent GI Bleeding and Pump Thrombosis

Simon Maltais, MD, PhD, Mayo Clinic, Rochester, MN, USA

Teaching/Discussion Points

  1. Definition, risk factors, and the inevitable "conundrum".
  2. Treatment of recurrent GI bleeding ─ overreacting on an imprecise science?
  3. Treatment of clotting while bleeding: how to treat medically, and when to refer for surgery.
  4. Evidence-based approach for pump thrombosis: from prevention to treatment algorithm.
  5. Implications and management of neurologic events on treatment.

9:35 AM

CASE SCENARIO: Management of Cerebrovascular Hemorrhagic Accidents

Chris Hayward, MD, St. Vincent's Hospital, Sydney, Australia

Teaching/Discussion Points

  1. Epidemiology and risk factors for intracerebral hemorrhage (ICH) in the MCS population.
  2. After the bleed, where to next? What are the immediate management priorities?
  3. Recommendations for anticoagulation in the setting of intracerebral hemorrhage.
  4. Current evidence for alternate anticoagulation options available to minimize ICH.
  5. Should we expect a poor outcome post ICH?

10:05 AM – 10:30 AM  
COFFEE BREAK

10:30 AM – 11:30 AM

SMALL GROUP INTERACTIVE DISCUSSION C: PATIENT SELECTION AND MANAGEMENT (I)

**Moderator:** Stavros Drakos, MD, PhD

10:30 AM

CASE SCENARIO: Bridge to Recovery: From Prediction to Implementation

Snehal Patel, MD, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA

Teaching/Discussion Points

  1. What accounts for the observed differences in rates of recovery between registry analysis and prospective single center studies?
  2. Managing and testing for recovery is hard work... can we target specific populations to limit the effort? – The role of clinical prediction tools.
  3. The role of adjuvant pharmacologic therapy in addition to mechanical unloading of the left ventricle to promote reverse remodeling.
  4. Practical considerations for cardiac recovery testing – when, how, and what are the endpoints.
  5. Recovery or remission? Histopathologic changes and long term follow up of explanted patients.

11:00 AM

CASE SCENARIO: Optimizing the Exercise Capacity of Chronic MCS Pts: Implications for Heart Recovery Assessment

Bart Meyns, MD, PhD, University Hospitals Leuven, Leuven, Belgium

Teaching/Discussion Points

  1. Indicate the limitations of exercise capacity in MCS patients, the evolution in time after MCS implantation and illustrate the effect of pump rotational speed.
  2. Explain the mechanism of limitation of exercise capacity and learn from patient variability.
  3. Indicate the role of potential underlying mechanisms such as underlying left and right ventricular function, anemia, and peripheral muscle deficiencies. 
  4. Understand the differences in exercise performance of patients after heart transplantation.
  5. Draw conclusions on how to optimize exercise capacity

11:30 AM – 11:35 AM

Speakers switch rooms; delegates remain seated

11:35 AM – 12:35 PM

SMALL GROUP INTERACTIVE DISCUSSION D: PATIENT SELECTION AND MANAGEMENT (II)

**Moderator:** Ivan Netuka, MD, PhD

11:35 AM

CASE SCENARIO: Early and Late RV Failure: From Prediction to Management

Lars Lund, MD, PhD, Karolinska University Hospital, Stockholm, Sweden

Teaching/Discussion Points

  1. RV failure risk prediction: how useful are risk prediction tools and models?
  2. RV failure risk minimization: pre- and peri-operative measures.
  3. TAH vs. BiVAD vs. temporary RVAD: how to select and deciding on prophylactic versus "as needed" RVAD?
  4. Post-op management: speed optimization and medical therapy. 
  5. Late RV failure: prediction, prevention and management.

12:05 PM

CASE SCENARIO: Minimally Invasive Surgical Approaches from Implant to Explant

Anson Cheung, MD, St. Paul's Hospital, Vancouver, Canada

Teaching/Discussion Points

  1. Advantages and disadvantages of less invasive surgical MCS device implantation
  2. Technical "do" and "don't" for less invasive surgical MCS device implantation
  3. Alternative outflow options for usual anatomy
  4. Technical tips for less invasive LVAD explantation for cardiac recovery

12:35 PM – 12:50 PM  
CLOSING REMARKS

Ivan Netuka, MD, PhD, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

12:50 PM

ADJOURN **  
**

SCIENTIFIC PROGRAM - AFTERNOON CLASS SCHEDULE

1:45 PM – 2:00 PM  
WELCOME AND INTRODUCTIONS   
Stavros Drakos, MD, PhD, University of Utah School of Medicine, Salt Lake City, UT, USA

2:00 PM – 3:00 PM

SMALL GROUP INTERACTIVE DISCUSSION A: ACUTE MCS FOR PROFOUND CARDIOGENIC SHOCK/INTERMACS 0-1 PROFILES

**Moderator:** **** Stavros Drakos, MD, PhD

2:00 PM

CASE SCENARIO: Management Challenges for 'Crash and Burn' Patients: 'Shock Team' Approach to MCS

Hiroo Takayama, MD, Columbia University, New York, NY, USA

Teaching/Discussion Points

  1. Challenges of assessing patients in profound cardiogenic shock: 
    1. Lack of universally accepted classification system of cardiogenic shock and its influence on patient management
    2. Important factors to consider at initial evaluation
  2. Challenges in choosing the appropriate timing for MCS
  3. Challenges in choosing the appropriate MCS device 
    1. Theoretical advantages/disadvantages of each device
    2. Existing clinical evidence
  4. SHOCK team approach to cardiogenic shock: patient benefits and logistical difficulties
  5. Initial attempts in developing an algorithm for MCS therapy for cariogenic shock

2:30 PM

CASE SCENARIO: Transition from Short to Long-Term Support

Keith Aaronson, MD, University of Michigan, Ann Arbor, MI, USA

Teaching/Discussion Points

  1. When is the optimal time to transition from temporary to durable MCS?
  2. How should you I assess and prioritize end organ function in the decision to proceed with durable MCS?
  3. How does temporary MCS affect the risk of RV failure post durable VAD?
  4. What are the other considerations when bridging from temporary to durable MCS?

3:00 PM – 3:05 PM

Speakers switch rooms; delegates remain seated

3:05 PM – 4:05 PM

**SMALL GROUP INTERACTIVE DISCUSSION B:** **COMPLEX COAGULATION ISSUES IN MCS PATIENTS**

**Moderator:** Ivan Netuka, MD, PhD

3:05 PM

CASE SCENARIO: Recurrent GI Bleeding and Pump Thrombosis

Simon Maltais, MD, PhD, Mayo Clinic, Rochester, MN, USA

Teaching/Discussion Points

  1. Definition, risk factors, and the inevitable "conundrum".
  2. Treatment of recurrent GI bleeding ─ overreacting on an imprecise science?
  3. Treatment of clotting while bleeding: how to treat medically, and when to refer for surgery.
  4. Evidence-based approach for pump thrombosis: from prevention to treatment algorithm.
  5. Implications and management of neurologic events on treatment.

3:35 PM

CASE SCENARIO: Management of Cerebrovascular Hemorrhagic Accidents

Chris Hayward, MD, St. Vincent's Hospital, Sydney, Australia

Teaching/Discussion Points

  1. Epidemiology and risk factors for intracerebral hemorrhage (ICH) in the MCS population.
  2. After the bleed, where to next? What are the immediate management priorities?
  3. Recommendations for anticoagulation in the setting of intracerebral hemorrhage.
  4. Current evidence for alternate anticoagulation options available to minimize ICH.
  5. Should we expect a poor outcome post ICH?

4:05 PM – 4:30 PM  
COFFEE BREAK

4:30 PM – 5:30 PM

SMALL GROUP INTERACTIVE DISCUSSION C: PATIENT SELECTION AND MANAGEMENT (I)

**Moderator:** Stavros Drakos, MD, PhD

4:30 PM

CASE SCENARIO: Bridge to Recovery: From Prediction to Implementation

Snehal Patel, MD, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA

Teaching/Discussion Points

  1. What accounts for the observed differences in rates of recovery between registry analysis and prospective single center studies?
  2. Managing and testing for recovery is hard work... can we target specific populations to limit the effort? – The role of clinical prediction tools.
  3. The role of adjuvant pharmacologic therapy in addition to mechanical unloading of the left ventricle to promote reverse remodeling.
  4. Practical considerations for cardiac recovery testing – when, how, and what are the endpoints.
  5. Recovery or remission? Histopathologic changes and long term follow up of explanted patients.

5:00 PM

CASE SCENARIO: Optimizing the Exercise Capacity of Chronic MCS Pts: Implications for Heart Recovery Assessment

Bart Meyns, MD, PhD, University Hospitals Leuven, Leuven, Belgium

Teaching/Discussion Points

  1. Indicate the limitations of exercise capacity in MCS patients, the evolution in time after MCS implantation and illustrate the effect of pump rotational speed.
  2. Explain the mechanism of limitation of exercise capacity and learn from patient variability.
  3. Indicate the role of potential underlying mechanisms such as underlying left and right ventricular function, anemia, and peripheral muscle deficiencies. 
  4. Understand the differences in exercise performance of patients after heart transplantation.
  5. Draw conclusions on how to optimize exercise capacity

5:30 PM – 5:35 PM

Speakers switch rooms; delegates remain seated

5:35 PM – 6:35 PM

SMALL GROUP INTERACTIVE DISCUSSION D: PATIENT SELECTION AND MANAGEMENT (II)

**Moderator:** Ivan Netuka, MD, PhD

5:35 PM

CASE SCENARIO: Early and Late RV Failure: From Prediction to Management

Lars Lund, MD, PhD, Karolinska University Hospital, Stockholm, Sweden

Teaching/Discussion Points

  1. RV failure risk prediction: how useful are risk prediction tools and models?
  2. RV failure risk minimization: pre- and peri-operative measures.
  3. TAH vs. BiVAD vs. temporary RVAD: how to select and deciding on prophylactic versus "as needed" RVAD?
  4. Post-op management: speed optimization and medical therapy. 
  5. Late RV failure: prediction, prevention and management.

6:05 PM

CASE SCENARIO: Minimally Invasive Surgical Approaches from Implant to Explant

Anson Cheung, MD, St. Paul's Hospital, Vancouver, Canada

Teaching/Discussion Points

  1. Advantages and disadvantages of less invasive surgical MCS device implantation
  2. Technical "do" and "don't" for less invasive surgical MCS device implantation
  3. Alternative outflow options for usual anatomy
  4. Technical tips for less invasive LVAD explantation for cardiac recovery

6:35 PM – 6:50 PM  
CLOSING REMARKS

Ivan Netuka, MD, PhD, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

6:50 PM

ADJOURN

# ISHLT ACADEMY

## MASTER CLASS IN PULMONARY HYPERTENSION

Tuesday, April 4, 2017

Scientific Program Committee

Chair:  Myung Park, MD, Houston Methodist, Houston, TX, USA

Co-Chair: Ioana Preston, MD, Tufts Medical Center, Boston, MA, USA

Members: Robert Frantz, MD, Mayo Clinic, Rochester, MN, USA

Marco Guazzi, MD, PhD, IRCCS Pol San Donato, Milan, Italy

Manreet Kanwar, MD, Allegheny General Hospital, Pittsburgh, PA, USA

Steven Nathan, MD, Inova Fairfax Hospital, Falls Church, VA, USA

Course Summary

The Pulmonary Hypertension (PH) Master Class is intended for members with higher levels of expertise (completed the core curriculum course on PH and/or primary practice in PH ≥ 5 years) who have managed patients with one or more of the topics intended for discussion. The course setting will generate a highly interactive environment composed of a small group of individuals and designed to enhance individual expertise and network development. Utilizing the concept of "convergent discussion" and the technique of "audience response system", faculty moderators will use complex situations and controversial statements during practical case presentations in order to lead the group through active audience participation, towards specific answers based on practice gaps and learning objectives. The MCS Master Class is arranged in advanced breakout sessions for every participant to take full advantage of an integrated curriculum and the exceptional networking opportunity. The four topics covered include: advanced pulmonary arterial hypertension (PAH Group 1); PH due to left heart failure (PH Group 2); PH due to advanced lung disease (PH Group 3); and chronic thromboembolic PH (CTEPH, PH Group 4). The topics chosen will cover the major aspects of various forms of PH and highlight the significant differences in the diagnosis and management of these entities. We anticipate that this method of collaborative and interactive learning will lead to application and integration of new knowledge into participant practice.

Practice Gaps

**1:** Advanced medical therapies and treatment algorithms for PAH have evolved tremendously in the recent years. The management of patients with advanced PAH and acute (or acute on chronic) right heart failure poses real challenges: their mortality is extremely high and salvage therapies used as bridge to a successful transplantation are complex. The implementation of advanced supportive measures in a failing right heart such as parenteral prostanoid replacement therapies, inotropic support and ECMO are often delayed or never utilized in advanced PAH patients. Recently published literature identified significant gaps in the recognition of signs that require adjustment of therapies in PAH management, including usage of parenteral therapies. Therefore, there is a real practice gap that limits their appropriate use in selected patients.

**2:** The presence of right ventricular dysfunction in the setting of systolic heart failure (PH due to heart failure with reduced ejection fraction, PH-HFrEF) represents a complex challenge for practitioners. The use of advanced support systems such as LVADs in the setting of right heart failure needs very careful consideration, including detailed evaluation of the RV function with noninvasive and invasive tests; heart failure specialists may lack the intricate details of these complicated patients and will benefit from the expertise of our speakers in addressing these challenging and commonly encountered issues. Lastly, PH from left ventricular diastolic dysfunction (PH-HFpEF) is often refractory to currently available therapies and its management is very challenging. Moreover, therapies that are effective for PAH Group 1 have not been carefully evaluated in PH due to heft heart disease (PH Group 2). Therefore, a deep understanding of the pathophysiology of PH Group 2 and how it differs (or not) from PAH Group 1 is necessary before making a decision of whether or not to treat.

**3:** PH due to advanced lung disease (PH Group 3) occurs in the vast majority of patients being evaluated for lung transplant and is associated with increased mortality. Identification of PH, correct determination of PH type and decision whether or not to treat are complex aspects of care of patients with advanced lung disease. Because many patients in this category are being diagnosed when PH is already advanced, there is a clear gap in early recognition of PH Group 3. Assessment of patients with lung disorders such as pulmonary fibrosis, COPD and sarcoidosis for the presence and severity of PH is therefore an important step in improving their management.

**4:** Annual incidence rates of deep venous thrombosis (DVT) and pulmonary embolism (PE) are approximately 0.5 to 1.0 per 1000 inhabitants and CTEPH develops in approximately 2-15% of patients who had a PE. Therefore, the estimated prevalence of CTEPH is high. Several reports highlight the significant gaps that exist between guidelines and clinical practice in regards diagnostic approaches and management of CTEPH, such as the lack of utilization of the ventilation/perfusion scan for screening and delay or omission of referral to a specialized surgical center for evaluation of operability. Therapies for CTEPH have been recently diversified and include sophisticated surgical approaches such as pulmonary endarterectomy, balloon angioplasty and medical treatment. Therefore, reviewing and clarifying the diagnostic algorithm, as well as different therapeutic approaches will be of great benefit for physicians and allied health care practitioners.

Educational Goals

The overarching goal is to provide an advanced learning opportunity for specialists in the field of PH on the treatment of PAH Group 1, as well as PH in the setting of advanced left heart and lung disease and in chronic thromboembolic PH; all these entities have very different management approaches.

Target Audience

The target audience for this class includes pulmonologists/respirologists, cardiologists, thoracic surgeons, nurses, physician assistants, and allied health professionals with experience in PH. The course is intended for health care professionals whose primary practice is focused in PH for at least 5 years or who have completed the ISHLT Core Competency Course on PH.

Learning Objectives

Upon completion of the Master Class, participants will be able to:

  1. Initiate advanced therapies for PAH
  2. Apply advanced supportive measures in severe right heart failure
  3. Manage complex patients with HFpEF and HFrEF complicated with PH
  4. Understand pathophysiology, correctly diagnose and manage PH associated with advanced lung disease of different etiologies, such as emphysema, pulmonary fibrosis, or sarcoidosis.
  5. Correctly define the type and severity of vascular compromise in CTEPH
  6. Determine the best therapeutic option in CTEPH, such as surgical eligibility, medical treatment, or invasive nonsurgical approaches (balloon angioplasty).

Accreditation Statement

The International Society for Heart and Lung Transplantation (ISHLT) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation Statement

ISHLT designates this live activity for a maximum of 5.0 _AMA PRA Category 1 Credits.™_ Physicians should claim only the credit commensurate with the extent of their participation in the activity.

**ANCC Credit  
** AMEDCO is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

This course is co-provided by AMEDCO and ISHLT. Maximum of 5.0 contact hours.

Disclosure

Current guidelines state that participants in CME activities must be made aware of any affiliation or financial interest that may affect the program content or a speaker's presentation. Planners, Faculty and Chairs participating in this meeting are required to disclose to the program audience any real or apparent conflict(s) of interest related to the content of their presentations or service as Chair/Planner. These disclosures will be distributed at the meeting. Additionally, all speakers have been asked to verbally disclose at the start of their presentation if a product they are discussing is not labeled for the use under discussion or is still investigational.
SCIENTIFIC PROGRAM SCHEDULE

2:00 PM - 2:15 PM  
WELCOME AND INTRODUCTIONS

Myung Park, MD, Houston Methodist, Houston, TX, USA

2:15 PM – 3:15 PM

SMALL GROUP INTERACTIVE DISCUSSION A: ADVANCED PAH: CHALLENGES IN MANAGEMENT

**Moderator:** Robert Frantz, MD

2:15 PM

CASE SCENARIO: Idiopathic PAH with Advanced Right Ventricular Failure

Paul Corris, MB FRCP, Freeman Hospital, Newcastle Upon Tyne, United Kingdom

Teaching/Discussion Points

  1. Understanding of optimal management strategies for RV failure (diuretics, inotropes, pressors)
  2. Discuss the role of atrial septostomy and ECMO
  3. Timing of lung transplantation and factors impacting outcome

2:45 PM

CASE SCENARIO: PAH with Suboptimal Control on Double Combination Therapy: What Next?

Mardi Gomberg-Maitland, MD, Inova Heart and Vascular Institute, Falls Church, VA, USA

Teaching/Discussion Points

  1. Utilization of optimal therapy lags behind guideline recommendations. 
  2. Recognition of disease progression requires sophisticated integration of clinical, imaging and hemodynamic parameters that is insufficiently employed. 
  3. Discussion of when to initiate parenteral therapy and various options available
  4. Recognition of practice gaps suggesting that many PAH patients with advanced disease are not initiated on parenteral therapies and discussion of possible factors influencing this outcome

3:15 PM – 3:20 PM

Speakers switch rooms; delegates remain seated

3:20 PM – 4:20 PM

SMALL GROUP INTERACTIVE DISCUSSION B: Challenges in PH Due to Left Heart Disease: An Increasingly Recognized Complication

**Moderator:** Marco Guazzi, MD, PhD

3:20 PM

CASE SCENARIO: PH Due to Heart Failure with Reduced Ejection Fraction

Ray Benza, MD, Allegheny General Hospital, Pittsburgh, PA, USA

Teaching/Discussion Points

  1. Hemodynamic definition and its limitations
  2. Epidemiology and phenotypes. Understanding the role of the right ventricle in HFrEF
  3. Pathophysiology of PH-HFrEF and the importance of mitral regurgitation
  4. Discussion of transplant and advanced support in the presence of PH
  5. Targeting the pulmonary microcirculation; a critical appraisal of current therapies for PH-HFrEF

3:50 PM

CASE SCENARIO: PH Due to Heart Failure with Preserved Ejection Fraction

C. Dario Vizza, MD, University of Rome, Rome, Italy

Teaching/Discussion Points

  1. Hemodynamic and clinical definitions; 
  2. Epidemiology and phenotypic characteristics. 
  3. Challenging LV filling and diastolic properties: exercise vs fluid loading
  4. Challenges in the management of patients with HFpEF and significant RV dysfunction. Discussion whether targeting the pulmonary vasculature is effective and safe. **  
**

4:20 PM – 4:45 PM  
COFFEE BREAK

4:45 PM – 5:45 PM

SMALL GROUP INTERACTIVE DISCUSSION C: PH DUE TO ADVANCED LUNG DISEASE

**Moderator:** Steven Nathan, MD

4:45 PM

CASE SCENARIO: PH Due to Combined Chronic Obstructive Lung Disease and Pulmonary Fibrosis

Fernando Torres, MD, University of Texas Southwestern Medical Center, Dallas, TX, USA

Teaching/Discussion Points

  1. Understand the implications of PH in diffuse parenchymal lung disease
  2. Epidemiology: advances in screening techniques and diagnostic algorithms.
  3. Interpretation of hemodynamic testing in the setting of advanced lung disease
  4. Challenges in the treatment of advanced pulmonary vascular disease in patients with COPD and IPF. 
  5. Clinical trial conundrums

5:15 PM

**CASE SCENARIO: PH Associated with Sarcoidosis  
** Oksana Shlobin, MD, Inova Fairfax Hospital, Falls Church, VA, USA

Teaching/Discussion Points

  1. Is PH complicating sarcoidosis different to the PH of other forms of diffuse parenchymal lung disease? 
  2. What factors are unique to sarcoidosis? If PH in sarcoidosis similar to PAH Group 1?
  3. Epidemiology: the role of PH screening in sarcoidosis
  4. Implications with regards to transplantation
  5. Treatment options, limitations of current therapies

5:45 PM – 5:50 AM

Speakers switch rooms; delegates remain seated

5:50 PM – 6:50 PM

SMALL GROUP INTERACTIVE DISCUSSION D: CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION (CTEPH)

**Moderator:** Manreet Kanwar, MD

5:50 PM

CASE SCENARIO: CTEPH with Mixed Type 3 and Type 4 Disease

Irene Lang, MD, Medical University of Vienna, Vienna, Austria

Teaching/Discussion Points

  1. Distal disease: What is the right therapeutic approach?
  2. Is there a role for combined surgical (PTE) and medical (BPA) approach in type 3/4 combined disease?
  3. Surgical challenges in patients with distal disease
  4. Optimizing patient selection for surgical candidacy in patients with high pulmonary vascular resistance and distal disease

6:20 PM

CASE SCENARIO: CTEPH with Discordant Diagnostic Results Between Imaging, Hemodynamics and Clot Burden

William Auger, MD, University of California San Diego Medical Center, San Diego, CA, USA

Teaching/Discussion Points

  1. Patient selection for optimal therapeutic options for CTEPH
  2. Predicting surgical outcomes from pre-op data
  3. Diseases that mimic CTEPH
  4. Identifying patients with likely post PTE persistent PH

6:50 PM – 7:00 PM  
CLOSING REMARKS

Ioana Preston, MD, Tufts Medical Center, Boston, MA, USA

7:00 PM

ADJOURN

# AFFILIATE EVENTS

Tuesday, April 4

8:00 AM – 1:00 PM

U.S. CTEPH Registry Steering Committee Meeting

(Bankers Hill)

Attendees: The attendees will be the Steering Committee members of the U.S. CTEPH Registry. They are all Faculty members at academic medical centers.

9:00 AM - 5:00 PM

ISO/TC 150/SC 6/WG 6, Mechanical Circulatory Support Systems

(Cove)

Attendees: Physicians, surgeons, members of ISHLT Mechanical Circulatory Support Council, members of FDA, MCS industry partners, ISO/TC 150/SC 6/WG 6 members, domestic and international.

12:00 PM - 6:00 PM

Toronto Lung Transplant Program Annual Lung Transplant Biospecimen Workshop

(TBD)

Attendees: World-leading experts in lung transplantation and thoracic surgery, and/or experts in biobanking, sample storage, data collection and translational research. All attendees are active members of ISHLT.

Wednesday, April 5

7:00 AM – 8:00 AM

Consensus Statement on Donor Heart and Lung Procurement Writing Group

(Gaslamp B)

Attendees: The attendees will be taskforce leaders, and contributing writers for this project.

7:00 AM – 8:00 AM

Pulmonary AMR WorkGroup Steering Committee Meeting

(Gaslamp A)

7:00 AM – 8:00 AM

SUSTAIN-IT Investigators Meeting

(Cove Room)

Attendees: SUSTAIN-IT investigators and coordinators

12:30 PM - 2:30 PM

ISHLT Lung Quality of Life Workforce Meeting

(La Jolla AB)

Attendees: Cross-disciplinary group of pulmonologists, social workers, nurses

12:30 PM - 2:30 PM

UCSD Faculty Luncheon

(Promenade AB)

Attendees: UCSD Faculty

1:00 PM - 2:00 PM

I2C2 Latin American Group Meeting

(America's Cup A-D)

Attendees: Latin American transplant professional

1:15 PM - 2:15 PM

REVIVAL Steering Committee Meeting

(Pier Room)

Attendees: Principal investigators participating in the study, who will be in attendance at the conference. from various sites across the nation.

6:00 PM – 7:15 PM

Psychosocial Evaluation Consensus Workgroup Meeting

(Gaslamp A)

Attendees: Individuals who received invitations to join the Consensus workgroup and who have been participating in the project.

6:00 PM – 8:00 PM

IPLTC Meeting

(La Jolla AB)

Attendees: Pediatricians engaged in Pediatric Lung Transplantation with the aim to unite pediatric lung transplant centers worldwide, to promote interaction between lung transplant physicians to enhance the care of children with lung transplants or those being considered for lung Transplantation, to provide a forum for the exchange of ideas about the science and art of pediatric lung Transplantation, to establish and maintain a prospective database of pediatric lung transplant recipients.

6:00 PM – 9:00 PM

Inflammatory Burden Multicenter Study Meeting

(Ocean Beach Room)

Attendees: Members of the Pathology Council

7:00 PM - 8:30 PM

Immunomodulators Consensus Conference

(Hillcrest A-D)

Attendees: Consensus Conference invited participants

7:00 PM - 9:30 PM

CCTN Educational Meeting

(Mission Beach A-C)

Attendees: HF and transplant specialists, cardiologists and surgeons, nurses and trainees - all involved in heart transplant in Canada

7:30 PM – 10:00 PM

ICCAC Annual Meeting

(Grand Hall C)

Thursday, April 6

7:00 AM - 8:00 AM

EUROMACS Committee Meeting

(Gaslamp D)

Attendees: EUROMACS Members

8:00 AM - 9:15 AM

EUROMACS Members Meeting

(Gaslamp D)

Attendees: Surgeons and Cardiologists contributing to the EUROMACS Registry, as well as scientists who execute studies based on the data provided by EUROMACS

12:30 AM – 2:00 PM

ID Symposium Working Group Meeting

(Gaslamp D)

Attendees: Select members from the ID council (ISHLT members only) who have manifested interest in participating in this working group.

12:30 AM – 2:00 PM

NHLBI-NIH Follow-Up Meeting at ISHLT – Clinical Trial Design for cfDNA

(La Jolla AB)

Attendees: ISHLT attendees/Conference research Group.

7:00 PM - 8:30 PM

Immunomodulators Consensus Conference

(Gaslamp A-C)

Attendees: Consensus Conference invited participants

Friday, April 7

11:30 AM - 1:30 PM

IMACS Users Group Meeting

(Gaslamp A-C)

12:00 PM – 1:00 PM

I2C2 Asian Meeting

(America's Cup A-D)

Attendees: Asian Transplant Leaders

12:00 PM - 1:00 PM

Meeting of the ID Council Working Group on the Older Transplant and MCSD Recipient

(Old Town B)

Attendees: Interested ISHLT members from both the ID Council as well as other interested physicians, nurses, coordinators, pharmacists, and scientists from other Councils who are interested in the care and study of the older transplant or MCSD recipient.

5:30 PM – 7:00 PM

Barnes-Jewish Hospital/Washington University School of Medicine Reception

(Ocean Beach)

Attendees: BJH/Washington University physicians, fellows, etc.

# CORPORATE EVENTS AND INDUSTRY THEATERS LISTINGS

The following approved Corporate Events and Industry Theaters are taking place during the ISHLT Annual Meeting. All events are taking place at the Manchester Grand Hyatt Hotel unless noted as off-site. The Industry Theaters will take place inside the Exhibit Hall located in the Harbor Ballroom.

Monday, April 3

8:00 AM – 2:00 PM

**UNIVERSITY OF PITTSBURGH MEDICAL CENTER:** Donor Heart/Lung Procurement Simulation Lab

(The Center for the Future of Surgery, UCSD, 9500 Gilman Drive MC0740, Medical Education and Telemedicine Building, La Jolla, CA 92093)

Tuesday, April 4

12:00 PM – 5:00 PM

**ABBOTT:** Commercial Leadership Meeting

(Solona Beach AB)

4:00 PM – 8:00 PM

**CARDIOVASCULAR RESEARCH FOUNDATION:** Training and Education in Advanced Cardiovascular Hemodynamics

Supported by an educational grant from Abiomed

(Cortez Hill A-C)

Wednesday, April 5

6:30 AM – 8:00 AM

**MEDTRONIC:** Investigators Meeting

(Torrey Hills AB)

12:00 PM – 12:30 PM

**MEDTRONIC:** Investor & Analyst Briefing

(Golden Hill AB Room)

12:30 PM – 2:30 PM

**MEDTRONIC:** Lunch Symposium

(Grand Hall B)

12:30 PM – 2:30 PM

**ONE LAMBDA:** Precision Medicine in Transplantation: Reclassifying Graft Rejection and Injury with the Molecular Microscope and Integrative Diagnostics

(Hillcrest A-D)

6:00 PM – 7:00 PM

**ABBOTT:** MCS Turkish Physician Reception

(Cortez Hills A-C)

6:00 PM – 8:00 PM

**LUNG BIOENGINEERING:** Investigators Meeting

(Solana Beach AB)

6:30 PM – 9:30 PM

**ABBOTT:** CardioMEMS in PH Study Steering Committee Meeting

(Cove)

Thursday, April 6

6:30 AM – 8:00 AM

**ACTELION PHARMACEUTICALS:** Nordic Expert Group Meeting ****

(Cove)

6:30 AM – 8:00 AM

ALERE: VADWatch Outcomes

(Ocean Beach Room)

6:30 AM – 8:00 AM

**MEDTRONIC:** Investigators Meeting

(Promenade AB)

7:00 AM – 8:00 AM

**RELIANTHEART:** Clinical Breakfast Meeting

(Golden Hill AB Room)

7:30 AM – 9:30 AM

**ACTELION PHARMACEUTICALS:** Medical Debrief 1 Meeting

(Pier Room)

10:00 AM – 10:30 AM

**SENSIBLE MEDICAL:** Industry Theater

(Harbor I)

12:00 PM – 2:00 PM

**RELIANTHEART:** aVAD Surgical Users Group Lunch Meeting

(Golden Hill AB Room)

12:30 PM – 1:30 PM

**GENENTECH:** Industry Theater

(Harbor I)

12:30 PM – 1:30 PM

**MEDTRONIC:** Investigators Meeting

(Ocean Beach Room)

12:30 PM – 2:00 PM

**ABBOTT:** ELEVATE Investigators Meeting

(Cove)

12:30 PM – 2:00 PM

**BAYER:** Managing what's important to you and your PAH (WHO Group 1) patients. An interactive session on a treatment option for PAH (WHO Group 1) patients

(Coronado DE)

12:30 PM – 2:00 PM

**CORWAVE:** Focus Group Meeting

(Pier Room)

3:15 PM - 4:15 PM

**MEDTRONIC:** Industry Theater

(Harbor I)

6:00 PM – 8:00 PM

**NOVARTIS:** Recruitment Meeting

(Promenade AB Room)

Friday, April 7

7:00 AM – 8:00 AM

**ABBOTT:** Japanese MCS Breakfast Meeting

(Promenade AB Room)

7:00 AM – 8:00 AM

**SENSIBLE MEDICAL:** SMILE Study Investigator Meeting

(Golden Hill AB Room)

7:30 AM – 9:30 AM

**ACTELION PHARMACEUTICALS:** Medical Debrief 2 Meeting

(Cove Room)

11:30 AM – 1:30 PM

**CORWAVE:** Focus Group Meeting

(Pier Room)

11:30 AM – 1:30 PM

**GILEAD SCIENCES, INC.:** Clinical Decision-Making in PAH: Experts Explore the Evidence for Combination Therapy

(Hillcrest A-D)

12:00 PM – 1:30 PM

**ABBOTT:** MOMENTUM 3 Investigators Meeting

(Cortez Hill A-C)

12:00 PM – 1:30 PM

**RELIANTHEART:** aVAD Surgical Users Group Meeting

(Golden Hill AB Room)

12:30 PM – 1:30 PM

**MEDTRONIC:** Investigator Meeting

(Promenade AB)

6:00 PM – 8:00 PM

**ABBOTT:** Product Fair

(off-site venue)

7:30 PM – 10:30 PM

**MALLINCKRODT/THERAKOS:** Meet the Expert Reception – Immune Modulation of Sensitized Patients

(off-site venue)

# EXHIBIT HALL FLOOR PLAN

# 2017 EXHIBITORS AND BOOTH NUMBERS

205 | Abbott (Formerly St. Jude Medical)

---|---

416 | Abiomed, Inc.

422 | Actelion Pharmaceuticals US, Inc.

106 | ActiCare Health

603 | Alere VADCare Program

524 | Astellas

105 | Bayer

222 | Bellerophon Therapeutics

609 | Berlin Heart, Inc.

516 | BiologicTX

224 | Bridge to Life

121 | CareDx

118 | CryoLife

225 | DNV GL Healthcare

220 | Elsevier

520 | Essential Pharmaceuticals, LLC

613 | Evaheart, Inc.

325 | Forever Flawless

218 | Genentech, A Member of the Roche Group

108 | Getinge Group

317 | Gilead Sciences, Inc.

125 | HemoCue America

423 | International Institute for the Advancement of Medicine

117 | ISHLT Mechanically Assisted Circulatory Support Registry (IMACS)

120 | ISHLT Registries

318 | Jarvik Heart, Inc.

522 | Joe DiMaggio Children's Hospital at Memorial

420 | Kroger Specialty Pharmacy

111 | Medtronic

518 | Millar, Inc.

607 | Miller Pharmacal Group, Inc.

417 | One Lambda, A Thermo Fisher Scientific Brand

124 | OTTR, Inc.

321 | Paragonix Technologies, Inc.

119 | Pediatric Heart Transplant Study (PHTS)

324 | Piedmont Healthcare

316 | Scanlan International, Inc.

320 | Sensible Medical, Inc.

223 | Surrogen, A Recombinetics Company

216 | SynCardia Systems, LLC

217 | Tandem Life

104 | Texas Children's Hospital

305 | Transmedics, Inc.

221 | The Transplantation Society

122 | TS Consulting

421 | United Therapeutics

425  | Waters Medical Systems, LLC

424 | Wexler Surgical

323 | Wound Care Resources

311 | XVIVO Perfusion AB

# 2017 EXHIBITOR PRODUCT DESCRIPTIONS

ABBOTT (FORMERLY ST. JUDE MEDICAL) Booth #205

6035 Stoneridge Dr.

Pleasanton, Ca. 94588 – USA

www.sjm.com

At Abbott, we're committed to helping you live your best possible life through the power of health. For more than 125 years, we've brought new products and technologies to the world — in nutrition, diagnostics, medical devices and branded generic pharmaceuticals — that create more possibilities for more people at all stages of life. Today, 94,000 of us are working to help people live not just longer, but better, in the more than 150 countries we serve.

Connect with us at www.abbott.com, on Facebook at www.facebook.com/Abbott and on Twitter @AbbottNews and @AbbottGlobal.

ABIOMED, INC. Booth #416

22 Cherry Hill Drive

Danvers, MA

www.abiomed.com

Based in Danvers, Massachusetts, Abiomed, Inc. is a leading provider of medical devices that provide circulatory support. Our products are designed to enable the heart to rest by improving blood flow and/or performing the pumping of the heart.

The Company's portfolio of products and services offer healthcare professionals an array of choices across a broad clinical spectrum. From the world's first total replacement heart to the World's Smallest Heart Pump, 1/100th the size of the heart with rapid and simple insertion, Abiomed is dedicated to finding ways to bring the most advanced and beneficial technology to patients and physicians.

For additional information, please visit: www.abiomed.com.

ACTELION PHARMACEUTICALS US, INC. Booth # 422

5000 Shoreline Court South

San Francisco CA, 94080

www.actelionus.com

Actelion Ltd. is a leading biopharmaceutical company focused on the discovery, development, and commercialization of innovative drugs for diseases with significant unmet medical needs.

ACTICARE HEALTH Booth #106

6111 Southfront Road, Suite M

Livermore, CA 94551

http://acticarehealth.com

ActiCare Health (Booth #106) enables resource-constrained coordinators to serve more outpatients with better efficiency through a state-of-the-art telehealth platform and 24x7 support, empowering both patients and clinicians to achieve improved outcomes with reduced stress. In response to the immense administrative and operational challenges faced by VAD and transplant departments, we've designed a program to provide enhanced visibility into patients' health status, modernize patient safety and communication, optimize discharge plan adherence, and minimize adverse clinical and financial events. Our program is designed to positively affect health outcomes and quality of life, enhance care coordination and staff efficiency, and reduce costs.

ALERE VADCARE PROGRAM Booth #603

30 South Keller Road

Orlando, FL

www.alerevadcare.com

The comprehensive Alere VADCare® Program helps you carefully and efficiently manage your patients after discharge to reduce the risk of hospital readmission. Alere fully supports the transition of VAD patients from hospital to home. Patients receive all of the necessary equipment and wound care supplies they need to take care of their VAD equipment and driveline exit site. Additional services through the Alere VADWatch® program include home INR monitoring; weight and blood pressure management; and tracking of VAD metrics in the Alere VADWatch® Data Management application, which gives clinicians secure, anytime access to patient data.

ASTELLAS Booth #524

Northbrook, IL

BAYER Booth #105

100 Bayer Blvd

Whippany, NJ 07981

www.bayer.com

Bayer is a global enterprise with core competencies in the Life Science fields of health care and agriculture. Its products and services are designed to benefit people and improve their quality of life. At the same time, the Group aims to create value through innovation, growth and high earning power.

BELLEROPHON THERAPEUTICS Booth #222

184 Liberty Corner Road, Suite 302

Warren, NJ 07059

We are a clinical-stage biotherapeutics company focused on developing innovative products at the intersection of drugs and devices that address significant unmet medical needs in the treatment of cardiopulmonary diseases. Three product candidates are in development under our INOpulse platform, a proprietary pulsatile nitric oxide device system. The first is for the treatment of pulmonary arterial hypertension (PAH), which is currently in Phase 3 clinical testing. The other two product candidates are for the treatment of pulmonary hypertension associated with chronic obstructive pulmonary disease (PH-COPD) and pulmonary hypertension associated with idiopathic pulmonary fibrosis (PH-IPF) which are both in Phase 2 development.

BERLIN HEART, INC. Booth #609

200 Valleywood Rd. Suite B100

The Woodlands, TX 77380

www.berlinheart.de

Berlin Heart, the only company worldwide, that develops, manufactures and distributes VADs for patients of every age and body size. EXCOR® Pediatric provides medium to long-term circulatory support specifically for infants and children awaiting heart transplants. EXCOR Pediatric is approved for use in the USA under HDE regulations by FDA.

BIOLOGICTX Booth #516

40-D Commerce Way

Totowa, NJ 07512

www.BiologicTx.com

BiologicTx is a national specialty pharmacy that joins the administration of therapeutics, research, and digital health to advance the practice of solid organ transplant and chronic specialties. BiologicTx is comprised of four operating segments: BiologicTx Pharmacy and Therapeutic Services, BiologicTx Clinical Trials™, BiologicTx Sequence, and BiologicTx Paired Donation™.

BRIDGE TO LIFE Booth #224

Northbrook, IL

CAREDX, INC. Booth #121

3260 Bayshore Blvd

Brisbane, CA

www.caredx.com

CareDx, Inc., headquartered in Brisbane, California, is a global molecular diagnostics company focused on the discovery, development and commercialization of clinically differentiated, high-value diagnostic solutions for transplant patients. The Company markets AlloMap®, a gene expression test that aids clinicians in identifying heart transplant patients with stable graft function who have a low probability of moderate to severe acute cellular rejection. CareDx is pursuing the development of additional products for transplant monitoring using a variety of technologies, including AlloSure™, a proprietary next-generation sequencing-based test to detect donor-derived cell-free DNA after transplantation.

CRYOLIFE Booth #118

1655 Roberts Blvd, NW

Kennesaw, GA 30144

www.cryolife.com

CryoLife® is one of the world's leading contemporary medical device companies providing preserved human cardiac and vascular tissues, surgical adhesives and sealants, cardiac lasers, PhotoFix™ bovine pericardium patch, and most recently, On-X® prosthetic heart valves. CryoLife's products and tissues have been used in an estimation of >1,000,000 procedures worldwide.

DNV GL HEALTHCARE Booth #225

Katy, TX

ELSEVIER Booth #220

Radarweg 29

1043 NX Amsterdam

The Netherlands

www.elsevier.com

Elsevier is a world-leading provider of information solutions that enhance the performance of science, health, and technology professionals, empowering them to make better decisions, deliver better care, and sometimes make groundbreaking discoveries that advance the boundaries of knowledge and human progress. Elsevier provides web-based, digital solutions — among themScienceDirect, Scopus, Research Intelligence and ClinicalKey — and publishes over 2,500 journals, including The Lancet and Cell, and more than 35,000 book titles, including a number of iconic reference works. Elsevier is part of RELX Group, a world-leading provider of information and analytics for professional and business customers across industries.

ESSENTIAL PHARMACEUTICALS, LLC Booth #520

100 Princeton South Corporate Center

Suite 140

Ewing NJ 08628

www.essentialpharma.com

www.custodiol.com

Essential Pharmaceuticals, LLC is a specialty pharmaceutical company devoted to the development and sales of pharmaceutical and biopharmaceutical products including Custodiol® HTK organ preservation solution. Originally developed for cardiac surgery, Custodiol® HTK offers superior convenience due to its easy handling characteristics, water like viscosity and no need for additives or filters which makes it a preferred solution for many transplant centers.

EVAHEART, INC. Booth #613

6655 Travis St. Ste 590

Houston, TX 77030 USA

www.evaheart-usa.com

The EVAHEART Left Ventricular Assist System (LVAS)™ is a continuous-flow, hydraulically levitated centrifugal pump designed to support patients with end-stage heart failure as bridge-to-transplant therapy. The EVAHEART LVAS has been commercially available in Japan since 2010 and has successfully obtained CE Marking approval.

Evaheart, Inc. (EVI) is a medical device company based in the Texas Medical Center of Houston. EVI was established to gain regulatory approval and commercialize the EVAHEART LVAS™ in North America and to start distribution in Europe. Under an FDA-approved IDE, a bridge-to-transplant (BTT) clinical trial of the EVAHEART LVAS™ is ongoing in the US.

FOREVER FLAWLESS Booth #325

Norcross, GA 30071

GENENTECH, A MEMBER OF THE ROCHE GROUP Booth #218

1 DNA Way

South San Francisco, CA 94080

www.gene.com

For more than 40 years, we've been following the science, seeking solutions to unmet medical needs. As a proud member of the Roche Group, we make medicines to treat patients with serious medical conditions.

We are headquartered in South San Francisco, California.

GETINGE GROUP Booth #108

45 Barbour Pond Drive

Wayne, NJ 07470

Getinge Group is a leading global provider of products and systems that contribute to quality enhancement and cost efficiency within healthcare and life sciences. We operate under the three brands of ArjoHuntleigh, Getinge and Maquet. Our unique value proposition mirrors the continuum of care for patients. We build quality and safety into every system and offer solutions that enhance efficiency throughout the clinical pathway. With our first-hand experience and close partnerships with industry leaders, we are able to exceed our customers' expectations. With a genuine passion for life, we work to improve patients' lives every day – both today and tomorrow.

GILEAD SCIENCES, INC. Booth #317

333 Lakeside Dr

Foster City, CA 94404

www.gilead.com

Gilead Sciences, Inc. is a research-based biopharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. We strive to transform and simplify care for people with life-threatening illnesses around the world. Gilead's portfolio of products and pipeline of investigational drugs includes treatments for HIV/AIDS, liver diseases, cancer, inflammatory and respiratory diseases, and cardiovascular conditions.

HEMOCUE AMERICA Booth #125

Brea, CA

INTERNATIONAL INSTITUTE FOR THE ADVANCEMENT OF MEDICINE Booth #423

Edison, NJ

ISHLT MECHANICALLY ASSISTED CIRCULATORY SUPPORT REGISTRY (IMACS) Booth #117

701 19TH Street South, LHRB 790

Birmingham, AL 35294

http://www.ISHLT.org/registries/mcsdDatabase.asp

IMACS is an international registry intended to enroll and follow patients who receive durable mechanically assisted circulatory support devices (MCSD) in all countries and hospitals that wish to participate. Durable devices are defined as those devices that are capable of allowing patient discharge with the device in place.

The primary goal of the IMACS Registry is to create, implement and analyze a registry that contains high standards for complete enrollment of patients and complete and accurate submission of MCSD data that allows participating centers to engage in important outcomes research about mechanical support devices.

ISHLT REGISTRIES Booth #120

700 N 4th Street

Richmond, VA 23219

www.ISHLT.org

ISHLT Thoracic Transplant Registry

ISHLT DCD Registry

ISHLT Pediatric Heart Failure Registry

JARVIK HEART, INC. Booth #318

333 West 52nd St

New York, NY 10019

www.jarvikheart.com

Jarvik Heart, Inc. is a privately held, New York based company that develops and manufactures miniaturized heart assist devices for the treatment of severe heart failure. The Jarvik 2000 is a battery-powered axial-flow left ventricular assist device (LVAD). It is the smallest implantable blood pump available for the long-term treatment of Heart Failure. The Jarvik 15mm VAD has been designed for pediatric patients and will enter a clinical trial in the USA in 2017.

JOE DIMAGGIO CHILDREN'S HOSPITAL AT MEMORIAL Booth #522

Hollywood, FL

KROGER SPECIALTY PHARMACY Booth #420

7373 Lincoln Way

Garden Grove, CA 92841

www.krogerspecialtypharmacy.com

www.krogerspecialtyinfusion.com

Kroger Specialty Pharmacy is a clinical pharmacy that offers highly individualized and comprehensive Total Life Care programs to patients and their families. We blend a high-touch, caring patient experience with specialized clinical knowledge, personalized care programs, and administrative expertise. Kroger Specialty Pharmacy provides specialty medication and support services for Crohn's Disease, Cystic Fibrosis, Gaucher's Disease, Growth Hormone Deficiency, Hemophilia and Bleeding Disorders, Hepatitis C, Hereditary Angioedema, HIV/AIDS, Immunoglobulin G (IVI/SQIg), Multiple Sclerosis, Oncology (Cancer), Psoriasis, Rheumatoid Arthritis, and Transplant.

MEDTRONIC Booth #111

710 Medtronic Parkway

Minneapolis, MN 55432-5604

www.medtronic.com

As a global leader in medical technology, services and solutions, Medtronic improves the lives and health of millions of people each year. We use our deep clinical, therapeutic and economic expertise to address the complex challenges faced by healthcare systems today. Let's take healthcare Further, Together. Learn more at Medtronic.com.

MILLAR, INC. Booth #518

6001-A Gulf Freeway

Houston, TX 77023

www.millar.com

Millar is committed to making the improbable possible in cardiovascular diagnostics and research by delivering products that enable a deeper understanding of hemodynamic function. From clean, pressure waveforms with the Mikro-CathTM pressure catheter to plotting the complete cardiac cycle with the Inca® PV Loop System, expert insight is within reach. Millar is a unique provider of cardiovascular products that cover device and drug development from the first animal model through the final clinical trial.

MILLER PHARMACAL GROUP, INC Booth #607

350 Randy Rd, Ste 2

Carol Stream, IL 60188

www.mgplusprotein.com

Miller Pharmacal's 'MG PLUS PROTEIN' (TM) magnesium supplement treats and prevents the hypomagnesemia caused by diuretics (or immunosuppressants) without causing the GI disturbances common with magnesium oxide. Each easy-to-swallow, glazed, non-enteric coated tablet contains 133 mg of magnesium.

ONE LAMBDA, A THERMO FISHER SCIENTIFIC BRAND Booth #417

21001 Kittridge Street

Canoga Park, CA 91303

www.onelambda.com

One Lambda, Inc., a Thermo Fisher Scientific brand, is a global leader in transplant diagnostics

offering a full range of HLA Typing and antibody monitoring products to support clinicians and

laboratories in the management of transplant patients. Visit www.onelambda.com to discover

how we can help you improve patient outcomes.

OTTR, INC. Booth #124

Omaha, NE

PARAGONIX TECHNOLOGIES, INC Booth #321

639 Granite Street, Suite 408

Braintree, MA 02184

PEDIATRIC HEART TRANSPLANT STUDY (PHTS) Booth #119

701 19th Street South, LHRB 781

Birmingham, AL 35294

www.uab.edu/medicine/phts

The Pediatric Heart Transplant Study (PHTS) is an international registry established in 1993 for pediatric patients listed for heart transplantation. PHTS is dedicated to the advancement of the science and treatment of children during listing for and following heart transplantation. The purposes of the group are to establish and maintain a prospective, event driven database for heart transplantation, to encourage and stimulate basic and clinical research in the field of pediatric heart transplantation, and to promote new therapeutic strategies. The ultimate goal is to improve patient outcomes. The registry resides at the University of Alabama at Birmingham.

PIEDMONT HEALTHCARE Booth #324

2727 Paces Ferry Rd, Suite 1-1100

Atlanta, GA 30339

<http://www.piedmont.org>

Piedmont Healthcare is a not-for-profit health system that serves nearly two million patients primarily in North Georgia but also across the state. Piedmont Healthcare is compromised of the following entities: Piedmont Athens Regional Medical Center, Piedmont Atlanta Hospital, Piedmont Fayette Hospital, Piedmont Henry Hospital, Piedmont Mountainside Hospital, Piedmont Newnan Hospital, Piedmont Newton Hospital, Piedmont Heart Institute, Piedmont Physician Group, Piedmont Clinic, and Piedmont Healthcare Foundation. Piedmont is revolutionizing healthcare in the Southeast by combining the traditions that have given us national prominence with cutting edge research and techniques that keep us on the forefront of medicine.

SCANLAN INTERNATIONAL, INC. Booth #316

One Scanlan Plaza

Saint Paul, Minnesota 55107

info@scanlangroup.com

www.scanlaninternational.com

Highest quality surgical products designed and manufactured by the Scanlan family since 1921. Over 3,000 titanium and stainless steel instrument designs including needle holders, forceps, scissors, clamps and specialty instruments. Featured instruments include the SCANLAN® LEGACY titanium needle holders and forceps, full line of VATS / MIS Thoracoscopic instruments including the Chitwood Clamp, Knot Pusher, and SUPER CUT™ Suture Cutter; Axial Handle needle holders and forceps; Scanlan® SUPER CUT™ Scissors and Rendina needle holder. Single-use products include: Scanlan® VASCU-STATT® bulldog clamps, Aorta/Vein Punch and A/C Locator® graft markers. Also offering custom instrument designs and modifications for your individual needs.

SENSIBLE MEDICAL, INC Booth #320

90 Park Avenue, Suite 1700

New York, New York 10016

www.sensible-medical.com

Sensible's vision is to lead a new standard of care for monitoring and managing patients with lung fluid problems, including Heart Failure. Our ReDS™ medical radar technology provides an accurate, absolute and actionable result, and is embedded in a non-invasive system which tracks and monitors their lung fluid in a single daily measurement. Results are uploaded to a cloud service and may be observed by a dedicated service center and the treating physician to better manage the patient. We believe our offering will become the standard of care to determine the right timing of the right treatment for such patients.

SURROGEN, A RECOMBINETICS COMPANY Booth #223

St. Paul, MN

SYNCARDIA SYSTEMS, LLC Booth #216

1992 E. Silverlake Rd

Tucson, AZ 85713

www.syncardia.com

The SynCardia temporary Total Artificial Heart (TAH-t), the world's most used artificial heart, is now available in two sizes to serve more patients. The 70cc TAH-t is FDA, Health Canada and CE approved as a bridge to transplant for patients with end-stage biventricular failure. The new, smaller 50cc TAH-t, CE approved in Europe and undergoing an Investigational Device Exemption clinical study in the U.S., is designed for patients of smaller stature, including women and adolescents. Stable patients can be discharged to wait for a matching donor heart at home using the Freedom® portable driver. Visit our booth to learn more.

TANDEMLIFE Booth #217

240 Alpha Drive

Pittsburgh, PA 15238

One Pump. Massive Potential. TandemLife (formerly, CardiacAssist, Inc.) exists to deliver Life Support Simplified, with one small pump enabling any type of extracorporeal circulatory support your patients may need. The TandemHeart pump was the driving force behind the world's first percutaneous left heart support system. We've added on to this legacy of innovation by developing three new product lines with the same reliability you've come to expect; TandemLife, TandemLung, and Protek Duo. Visit us to learn how we can empower your program to deliver breakthrough performance in extracorporeal support.

TEXAS CHILDREN'S HOSPITAL Booth #104

6621 Fannin St

Houston, TX 77030

www.texaschildrens.org

Texas Children's Hospital, a not-for-profit health care organization, is committed to creating a healthier future for children and women throughout the global community by leading in patient care, education and research. Consistently ranked as the best children's hospital in Texas, and among the top in the nation, Texas Children's has garnered widespread recognition for its expertise and breakthroughs in pediatric and women's health. The hospital includes the Jan and Dan Duncan Neurological Research Institute; the Feigin Center for pediatric research; Texas Children's Pavilion for Women, a comprehensive obstetrics/gynecology facility; Texas Children's Hospital West Campus; and Texas Children's Hospital The Woodlands.

TRANSMEDICS, INC. Booth #305

200 Minuteman Road,Suite 302

Andover, MA 01810

www.transmedics.com

The Organ Care System (OCS™) is the only portable, mutli-organ, normothermic ex-vivo perfusion platform that maintains donor organs in a functioning state outside of the body. The OCS™ System minimizes ischemic injury and allows for continuous clinical evaluation of organs to increase donor organ utilization and improve post-transplant clinical outcomes.

The OCS™ Heart, Lung and Liver systems are CE Marked in Europe. In the USA, they are Investigational Devices limited by Federal Law to Investigational Use.

THE TRANSPLANTATION SOCIETY Booth #221

505 Boulevard René-Lévesque Ouest, Suite 1401

Montreal, QC, Canada H2Z 1Y7

www.tts.org

Over the last 50 years The Transplantation Society has grown exponentially and has become the largest international transplant community. Established in 1966, it serves as the principle International forum for the advancement of both basic and clinical transplantation science throughout the world. The Transplantation Society is a Non-Governmental Organization (NGO) which is composed of over 6700 professionals including but not limited to, physicians, surgeons and scientists in over 105 countries. The Transplantation Society's mission is to provide the focus for global leadership in transplantation through the development of the science and clinical practice, scientific communication, continuing education and the guidance on ethical practice.

TS CONSULTING Booth #122

8255 Las Vegas Blvd

Las Vegas, NV 89123

UNITED THERAPEUTICS Booth #421

55 T.W. Alexander Drive

Research Triangle Park, NC 27709

www.uniter.com

Medical Affairs/Medical Information Booth supporting United Therapeutics' marketed products for the treatment of symptoms of pulmonary arterial hypertension. Also supporting near term and long term plans for the treatment of symptoms and cure of PAH/PH. Information on the Jenesis Awards, which supports junior investigators in the field of pulmonary hypertension, is available.

WATERS MEDICAL SYSTEMS, LLC Booth #425

2112 15th St NW

Rochester, MN 55901

www.wtrs.com

We, at Waters Medical Systems, design, manufacture, and market proprietary and generic products for organ preservation. Our products are essential for the success of organ transplantations. Our extensive clinical experience of over 45 years has forged the reputation of our products in terms of safety and efficiency.

Waters Medical Systems is a sister company of Institut Georges Lopez (known as IGL), located in France. Waters Medical Systems and IGL, together, represent a key player in the world of organ preservation, uniquely positioned by providing a comprehensive offer for the organ storage.

Products: WAVES Kidney Perfusion System, RM3 Kidney Perfusion System, Waters IGL Cold Storage Solution (CSS), Waters IGL Pulsatile Perfusion Solution (PPS), CELSIOR Cold Storage Solution.

WEXLER SURGICAL Booth #424

11333 Chimney Rock Rd, Suite 110

Houston, TX 77305

www.wexlersurgical.com

Wexler Surgical designs and manufactures a variety of titanium and stainless steel specialty surgical instruments and products for Cardiac, Vascular, Thoracic, and Micro Surgery.

Come see our VATS/MICS instruments and ask about our Optimus Series. Visit us online at www.wexlersurgical.com for more information about our products and services.

WOUND CARE RESOURCES Booth #323

4 Newbern Hwy

Yorkville, TN 38389

www.VADsupplies.com

www.woundcareresources.net

Wound Care Resources, a niche DME specializing in the formulation, usage and billing of surgical dressings since 2006, has been billing VAD dressing supplies nationwide since 2010. The company offers an extensive selection of surgical dressings and prepackaged customized kits with an emphasis on antimicrobials and unique "gentle" products for those having skin sensitivities associated with traditional adhesives and cleansers. WCR bills Medicare, Medicaid and commercial insurance for all products and dressings needed for VAD outpatient driveline maintenance.

XVIVO PERFUSION AB Booth #311

Box 53015

SE-400 14 Gothenburg, Sweden

www.xvivoperfusion.com

XVIVO Perfusion manufactures and markets solutions and systems for transplantation:

- Perfadex® for hypothermic flushing and preservation of donor lungs during transport

- STEEN Solution™ for normothermic ex vivo lung perfusion and evaluation

- XPS™ and LS™ platforms for warm perfusion and evaluation of lungs ex vivo, after donation and prior to transplantation

XPS™, disposables and the perfusates are CE-marked, approved in Canada, Australia and US. LS™ and disposables are approved in Europe, Canada and Australia.

XVIVO aims to increase the number of organs available for transplantation and transplantation success rates using new transplantation concepts and techniques.

# FUTURE ANNUAL MEETINGS

2018

38th Annual Meeting and Scientific Sessions

Nice, France

April 11-14, 2018

2019

39th Annual Meeting and Scientific Sessions

Orlando, FL, USA

April 3-6 2019

2020

40th Annual Meeting and Scientific Sessions

Montreal, Canada

April 2020

International Society for Heart and Lung

Transplantation

14673 Midway Road, Suite 200

Addison, TX 75001 USA

972-490-9495

www.ISHLT.org
