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Engineering HSC and IIT-JEE Mains and
advanced videos. Hello students today we
are studying chapter genetic basis of
inheritance in that we are studying topic
pleiotrophy now when I talk about pileo-
trophy it means the ability of a gene to
give multiple traits or characters what
does the sickle cell anemia is a pleio-
tropic segment or you can say for pleio
-trophism definition now how it is
let's turn
Pleiotrophy, Pleiotrophy do pielo
off mean smell and ability of a
particular stream or a leaf to have
multiple characteristics or multiple
effects is nothing but Pleiotrophy
for example sickle cell anemia now it
belongs to the domain of Pleiotrophy
diseases how does that happen how does
sickle cell anemia is a Pleiotrophy discuss
this blue topic disease is nothing but
interrelationships between different
metabolic pathways that is anabolic as
well as catabolic pathways that
contribute to different genotypes and
phenotypes that may lead to a certain
kind of disease sickle cell anemia is
one of them notice sickle cell anemia we
all know that we have our B C's in our
body now this IBC's have an ability to
carry oxygen along with the help of
hemoglobin in the red color of RBC's is
due to the hemoglobin present in it what
happened in sickles and it is that your
RBC's will become sickened and once your
irises lose their concave shape they
tend to become sickle shape when the you
become sickle shape they are enable or
they cannot carry hemoglobin on the
surface and once you have deficiency of
hemoglobin then it could create problem
just to carry your oxygen a lack of
oxygen may make you faint may make you
unable to walk certainly sensors carry
out certain work basically you may lose
your mental stability that sickle cell
anemia in Normal and supply o tropic
condition apart from that in white Rose
Villa has certain characteristics of Rio
Tropic tree that is the white eye
notation in Drosophila is one of the
reason of Clio tropic
diseases or clear prophecy
Clio trophy Perry talk about flow
trapping it is the ability of a team to
have multiple effects and leo drop ism
may include two types of diseases one a
sickle cell anemia that's in human
beings and another is the ion addition
in drosophila the basis of pure p is
nothing but the interrelationship
between the metabolic pathways or you
can say the chemical pathways present
inside human beings that may contribute
to different phenotypic results that is
if there is a change or you can say if
there is a miscommunication in certain
chemicals produced in certain metabolic
pathways there are chances that the
phenotypic change will produce an effect
in human beings
an example of this Clio Tropic trade is
sickle-cell anemia in human beings now
this is an genetic disease or genetic
disorder during this the primary effect
of the mutated gene or the dislocated
gene mutations could be point mutations
or it could be mutations in chromosome
but ATGC one of those course is system
to do this abnormal hemoglobin HP is
produced now in the global is what makes
you walk fast run fast gives you that
energy the iron-containing for ferrets
the subsidiary effects or you can say
the side effects of this you know globin
includes unless an amount of hemoglobin
includes sickle shape our disease there
will be no opposition available to carry
and so that knocks ition on hardly less
amount of oxygen which is to every part
of your body if you have to do any
strain its activity like jumping hopping
it could get affected you should can get
palpitating now this sequential analysis
will have a tendency to come and imagine
a situation in your body if the Odysseys
are clumping up or they're mixing
together who are going to carry the
hemoglobin and oxygen to different parts
of your body
how does respiration metabolic anabolic
processes in your body I will do what
students now sickle cell anemia is
something that if an individual has has
to deal with life you can be recessive
for sickle cell anemia or you can be one
who is a carrier not a develop the
syndrome but sometimes certain dominant
traits or strong traits fast inside
individual that make them which one more
second cell anemia it's not an eh
disease it can became inherited li and
one could develop the symptoms later on
now the symptoms can be little bit
savior to the far than part which could
be more severe for example there is
cramping of RBC's which make the blood
in a viscous manner and there is no
blood flow the blood flow is desktop
variety people will have low hemoglobin
level the CBC common so hemoglobin below
four point five or three point five they
tend to have more amount of vitamins
which is better meat
v6 students in this part of the chapter
would did we study was about pier topic
trade and how L ability of wanting to
control multiple effects and how it can
lead and it is something which is for a
sickle cell anemia in human beings and
white eye mutations in sha so feather on
this Mendel did study a lot
I don't yell act area with this concept
of future traits of your tropic
characteristics thank you
