
# Unofficial Satellite Events

## USE.01 - Optimizing Antithrombotic Therapy in Patients With Atrial Fibrillation Who Have an Acute Coronary Syndrome or Have Undergone PCI: New Data, New Directions

#### Philadelphia Marriott Downtown, Liberty Ballroom

### Friday, November 15, 2019, 7:00 PM - 9:00 PM

7:00 PM

Programming

# Joint Sessions

## CA.JS.625 - Cardiovascular Research Using iPS Cell Technology: Joint Session with AHA and The Japanese Circulation Society

#### 121A

### Saturday, November 16, 2019, 7:00 AM - 8:15 AM

7:00 AM

Moderator

Toyoaki Murohara, Nagoya, Japan

7:12 AM

Q&A

7:30 AM

Q&A

7:35 AM

iPSC-Derived Cardiac Tissue

Timothy J Kamp, Madison, WI

7:47 AM

Q&A

8:04 AM

Q&A

# Abstract Oral Session

## QU.AOS.507 - QCOR's Got Talent - High Impact Oral Abstracts: Arrhythmia Care

#### 202AB

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Rachel J Lampert, New Haven, CT

7:15 AM

Moderator

Sana M Al-khatib, Durham, NC

7:15 AM

Longitudinal Outcomes Associated With Non-Evidence-Based Implantable Cardioverter-Defibrillators Among Medicare Beneficiaries: A Report From the National Cardiovascular Data Registry

**Usama A Daimee** , Faisal Aslam, Craig S Parzynski, Nihar R. Desai, Jeptha P. Curtis, Yale Sch of Med, New Haven, CT

7:25 AM

Q & A

7:30 AM

Cost Effectiveness of Screening for Paroxysmal Atrial Fibrillation in Patients Undergoing Echocardiography

**Satish Ramkumar** , Hiroshi Kawakami, Baker Heart and Diabetes Inst, Melbourne, Australia; Edmond Wong, Monash Health, Clayton, Australia; Mark Nolan, Thomas H. Marwick, Baker Heart and Diabetes Inst, Melbourne, Australia

7:40 AM

Q & A

7:45 AM

The Impact of Knowledge Translation and Integrated Cardiovascular Care on Emergency Room Visits of Patients With Atrial Fibrillation

**Chrystina Kiwan** , Ahmed Alturki, McGill Univ Health Ctr, Montreal, QC, Canada; Isabelle Greiss, Ctr Hospier de L'Univ de Montreal, Montreal, QC, Canada; Teresa Kus, Hop Sacre-Coeur, Montreal, QC, Canada; Martine Montigny, Cite de Sante de Laval, Montreal, QC, Canada; Felix Ayala Paredes, Ctr Hospier de l'Univ de Sherbrooke, MONTREAL, QC, Canada; Jean-Francois Sarrazin, McGill Univ Health Ctr, Montreal, QC, Canada; Miguel Barrero Garcia, Ctr Hospier de Trois Rivieres, Montreal, QC, Canada; Robert Breton, Ctr Hospier de Chicoutimi, Montreal, QC, Canada; Gilles O'Hara, Magdi Sami, McGill Univ Health Ctr, Montreal, QC, Canada; Steeve Brulotte, Hotel-Dieu de Levis, St-redempteur, QC, Canada; Danielle Dion, Ctr Hospier de Beauce, Montreal, QC, Canada; Gaetan Houde, Clin Cardio Desilets, Montreal, QC, Canada; Franco Sandrin, Lakeshore General Hosp, L'ile-bizard, QC, Canada; Mladen Palaic, Hop General de Lakeshore, Montreal, QC, Canada; Vidal Essebag, McGill Univ Health Ctr, Montreal, QC, Canada; Chi Ming Chow, St-Michael Hosp, Toronto, QC, Canada; Thao Huynh, McGill Univ Health Ctr, Montreal, QC, Canada

7:55 AM

Q & A

8:00 AM

Reduced Dose Direct Oral Anticoagulants Compared to Warfarin With High Time in Therapeutic Range in Nonvalvular Atrial Fibrillation

**Martin Jansson** , Vilhelm Sjögren, Sara Sjalander, Fredrik Björck, Umeå Univ, Sundsvall, Sweden; Henrik Renlund, Uppsala Univ, Uppsala, Sweden; Bo Norrving, Lund Univ, Lund, Sweden; Anders Sjalander, Umeå Univ, Sundsvall, Sweden

8:10 AM

Q & A

8:15 AM

Competing Risk of Death and the Net Benefit of Apixaban in Older Adults With Atrial Fibrillation

**Sachin J Shah** , Univ of California, San Francisco, San Francisco, CA; Margaret C Fang, UCSF, San Francisco, CA; Daniel Singer, Massachusetts General Hosp/Harvard Medical Sch, Boston, MA; Alan S Go, Kaiser Permanente Northern Cal, Oakland, CA; Mark H Eckman, Univ of Cincinnati, Cincinnati, OH

8:25 AM

Q & A

# Cardiovascular Seminar

## VA.CVS.332 - Clinical and Research Controversies in Thrombosis and Women's Health

#### 103C

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Margo B Minissian, Los Angeles, CA

7:15 AM

Moderator

Mary Cushman, Colchester, VT

7:15 AM

Fact From Fiction: The Epidemiology of VTE in Women

Mary Cushman, Colchester, VT

7:30 AM

Thrombophilia Testing Should Be performed Routinely in Women With Recurrent Miscarriage

Gregory Piazza, Boston, MA

7:45 AM

Thrombophilia Testing Should Not Be Performed Routinely in Women With Recurrent Miscarriage

Shannon Bates, Hamilton, ON, Canada

8:00 AM

Managing Thrombosis as a Cause of Infertility: A Critical Appraisal of the Data

Elvira Grandone

8:15 AM

Panel Discussion

# Cardiovascular Seminar

## IM.CVS.267 - Diagnosis and Characterization of Coronary Microvascular Disease: Role of Imaging

#### 108B

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Parham Eshtehardi, Atlanta, GA

7:15 AM

Moderator

Viviany R Taqueti, Boston, MA

7:15 AM

Burden and Importance of Coronary Microvascular Disease

Parham Eshtehardi, Atlanta, GA

7:30 AM

Diagnosis of Coronary Microvascular Disease: Invasive Imaging

Carl J Pepine, Gainesville, FL

7:45 AM

Diagnosis of Coronary Microvascular Disease: Nuclear Perfusion Imaging

Sharmila Dorbala, Boston, MA

8:00 AM

Diagnosis of Coronary Microvascular Disease: CT and MR Imaging

Chiara Bucciarelli-Ducci, Bristol, United Kingdom

8:15 AM

Treatment Options and Future Perspective

ornella rimoldi, Milan, Italy

# Cardiovascular Seminar

## HY.CVS.453 - Emerging Therapies for Hypertension Management: Medical and Interventional

#### 108A

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Angela L Brown, Saint Louis, MO

7:15 AM

Moderator

Jan Danser, Rotterdam

7:15 AM

Angiotensinogen Suppression With Antisense Oligonucleotides and Small Interfering RNA

Jan Danser, Rotterdam

7:33 AM

Renal Denervation Overview - What Have We Learned Since Symplycity HTN-3

Michael Boehm, Homburg

7:50 AM

Targeting DHFR-eNOS Axis for the Treatment of Hypertension

Hua Linda Cai, Los Angeles, CA

8:13 AM

Updates on Endovascular Ultrasound Renal Nerve Ablation

Michael J Bloch, Reno, NV

# Cardiovascular Seminar

## HF.CVS.419 - HFpEF: What's New, What's Exciting, What May Work

#### 105AB

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Julio A Chirinos, Philadelphia, PA

7:15 AM

Moderator

Alanna A Morris, Atlanta, GA

7:15 AM

It's a Diagnosis of Exclusion- So Exclude the Other Causes!

Frederick Ruberg, Boston, MA

7:30 AM

Mechanical Problems Need Mechanical Solutions: Pericardiectomy and Interatrial Shunts

Martin M Lewinter, Burlington, VT

7:45 AM

Medical Solutions Will Work (Someday): Prior Trials and Those Coming

Orly Vardeny, Minneapolis, MN

8:00 AM

Debate: I Choose Machine Learning to Phenotype My Patients With HFpEF

Sanjiv J Shah, Chicago, IL

8:10 AM

Debate: I Choose Hemodynamics to Phenotype My Patients With HFpEF

Barry BORLAUG, Rochester, MN

8:20 AM

Q&A

# Cardiovascular Seminar

## AC.CVS.82 - Microvascular Coronary Disease: Update for the Practicing Clinician

#### 103A

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

John F Beltrame, Adelaide, Australia

7:15 AM

Moderator

Puja K Mehta, LA, CA

7:15 AM

Choosing and Interpreting a Noninvasive Test

Viviany R Taqueti, Boston, MA

7:28 AM

Who Should Be Referred for invasive Testing?

Nathaniel Smilowitz, New York, NY

7:41 AM

Medical Therapy

Janet Wei, Los Angeles, CA

7:54 AM

Additional Therapeutic Options

Amir Lerman, Rochester, MN

8:07 AM

Prognosis of Microvascular Coronary Disease

Jennifer Lewey, Philadelphia, PA

8:20 AM

Discussion

# Cardiovascular Seminar

## SA.CVS.425 - Multidisciplinary Case Discussions: An Interactive Session

#### 109AB

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

adanna akujuo, Albany, NY

7:15 AM

Moderator

jonathan leff, Bronx, NY

7:15 AM

Lead Extraction in the Cath Lab Goes South

Diana anca, New York, NY

7:30 AM

Hemorrhage After Surgery: Thrombotic Risks of Over-Treatment

Kamrouz Ghadimi, Durham, NC

7:45 AM

The Importance of the Echocardiographer in Cannulation Techniques

Mary Beth Brady, Baltimore, MD

8:00 AM

A Difficult Wean From Cardiopulmonary Bypass

Lisa Rong, New York, NY

8:15 AM

Expert Discussant

David DALESSANDRO, Boston, MA

# Cardiovascular Seminar

## CH.CVS.427 - New Kids on the Block: Expanding Frontiers in Pediatric Cardiology

#### 112AB

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Christopher Caldarone, Houston, TX

7:15 AM

Moderator

Alison Marsden, Stanford, CA

7:15 AM

The Role of Regenerative Medicne in Congenital Heart Disease

Sunjay Kaushal, Baltimore, MD

7:30 AM

Tissue Engineered Vascular Grafts

Toshiharu Shinoka, Columbus, OH

7:45 AM

Ex-vivo Heart Preservation

Gabe Owens, Ann Arbor, MI

8:00 AM

The Self- Powered Fontan

William Decampli, Orlando, FL

8:15 AM

Simulations to Predict Single Ventricle Patient-Specific Physiology

Tain-Yen Hsia

# Cardiovascular Seminar

## EA.CVS.189 - Postural Tachycardia Syndrome, Orthostatic Hypotension, and Autonomic Dysfunction: A Multi-Disciplinary Case Based Approach

#### 113BC

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Leila Laroussi, Montreal, QC, Canada

7:15 AM

Moderator

Mohamed Hamdan, Madison, WI

7:30 AM

Q & A

7:33 AM

Case Presentation: Is it POTS or IST?

Kenneth Mayuga, Cleveland, OH

7:38 AM

Perspectives From a Cardiac Electrophysiologist: POTS vs IST Diagnosis and Treatment

Kenneth Mayuga, Cleveland, OH

7:48 AM

Q & A

8:06 AM

Q & A

8:09 AM

Case Presentation: POTS in the Pediatric Population

Elizabeth Vickers Saarel, Cleveland, OH

8:14 AM

Perspectives From a Pediatric Cardiologist: Starting a Pediatric POTS Program

Elizabeth V Saarel, Cleveland, OH

8:24 AM

Q & A

# Cardiovascular Seminar

## CH.CVS.34 - Stress and Coping with Congenital Heart Disease - What Lessons have we Learned?

#### 111AB

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Gil Wernovsky, Washington, DC

7:15 AM

Moderator

Kathleen Mussatto, Milwaukee, WI

7:15 AM

Mothers and Fathers Experience Stress Differently - How Can We Help Each Cope Better?

Erica Sood, Wilmington, DE

7:30 AM

Adolescent and Young Adult Preferences for Discussing Advanced Care Directives

Melissa Cousino, Ann Arbor, MI

7:45 AM

The Influence of Disparities on Parental Stress and Coping: What Can We learn From Community-Based Research?

Wendy Nembhard, Little Rock, AR

8:00 AM

CHD-Related Stress in New Immigrants

Elizabeth Anne Greene, Albuquerque, NM

8:15 AM

Stress-Reduction for Pediatric Cardiology Providers - Heal Thyself!

Vicki A Freedenberg, Washington, D.C., DC

# Cardiovascular Seminar

## PH.CVS.163 - Update in CTEPH: From Bench to Bedside

#### 102AB

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Hyung J Chun, New Haven, CT

7:15 AM

Moderator

Bradley Wertheim, MA

7:15 AM

Moderator

Inderjit Singh, New Haven, CT

7:15 AM

Overview of Pathobiology of CTEPH, and the Role of PEA

Patricia Thistlethwaite, La Jolla, CA

7:25 AM

Discussion

7:30 AM

Inflammation and Impaired Angiogenesis in CTEPH

Rozenn QUARCK, LEUVEN, Belgium

7:40 AM

Discussion

7:45 AM

Risk Assessment in CTEPH

Paul Robert Forfia, Philadelphia, PA

7:55 AM

Discussion

8:00 AM

Cellular Heterogenelty in CTEPH

Sudarshan Rajagopal, Durham, NC

8:10 AM

Discussion

8:15 AM

The Past, Present and Future of CTEPH, and the Role of BPA

Irene M Lang, Vienna

8:25 AM

Discussion

# Early Career

## IN.EC.320 - CLCD Early Career Ancillary Session: Launch your Cardiology Career! A Heart Team Approach to Developing a Productive and Engaging Practice

#### Terrace Ballroom IV

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Nicole Reilly, Madison, WI

7:15 AM

Moderator

Ryan Kipp, Madison, WI

7:15 AM

Electrophysiology

N A Estes III, Pittsburgh, PA

7:25 AM

Imaging

Heather Johnson

7:35 AM

Heart Failure and Transplant

Lynne Stevenson, Nashville, TN

7:45 AM

Interventional Cardiology

Jacqueline Tamis-Holland, Tenafly, NJ

7:55 AM

Prevention

Dean Ornish, Sausalito, CA

8:05 AM

Panel Discussion

N A Estes III, Pittsburgh, PA

8:05 AM

Panel Discussion

Heather Johnson, Madison, WI

8:05 AM

Panel Discussion

Jacqueline Tamis-Holland, Tenafly, NJ

8:05 AM

Panel Discussion

Dean Ornish, Sausalito, CA

8:05 AM

Panel Discussion

Lynne Stevenson, Nashville, TN

# Featured Science

## FS.AOS.02 - Featured Science EP

#### 107AB

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Vincent Y SEE, Baltimore, MD

7:15 AM

IMPACT: Improving Esophageal Protection During Catheter Ablation for Atrial Fibrillation. A Double Blind Randomised Controlled Trial

**Mark Gallagher** , Lisa Leung, Anthony Li, Manav Sohal, Zia Zuberi, Abhay Bajpai, Jamal Hayat, John Louis-Auguste, St. George's Hosp, London, United Kingdom

7:23 AM

Discussion

7:26 AM

Atrioventricular Synchronous Pacing Using a Leadless Ventricular Pacemaker: Primary Results From the MARVEL 2 Study

**Larry A Chinitz** , NYU Langone Health, New York, NY; Surinder Kaur Khelae, Inst Jantung Negara, Kuala Lumpur, Malaysia; Christophe Garweg, Univ Hosp of Leuven, Leuven, Belgium; Joseph Chan, Prince of Wales Hosp, Hong Kong; Philippe Ritter, Hôpital Haut-Lévêque - CHU de Bordeaux, Pessac, France; Jens Brock Johansen, Odense Univ Hosp, Odense, Denmark; Venkata Sagi, Baptist Medical Ctr Jacksonville, Jacksonville, FL; Laurence Epstein, Northwell Health, Manhasset, NY; Jonathan P Piccini, Duke Univ Medical Ctr, Durham, NC; Mario Ignacio Pascual, -, New Orleans, LA; Lluis Mont, -, New Orleans, LA, Spain; Todd Jon Sheldon, Medtronic Inc, Mounds View, MN; Vincent Splett, Kurt Stromberg, Nicole Wood, Medtronic, Mounds View, MN; Clemens Steinwender, Kepler Univsklinikum Med Campus III., Linz, Austria

7:34 AM

Discussion

7:37 AM

Hot-Balloon Pulmonary Vein Isolation Registry Study (HARVEST Study): The Efficacy and Safety Data of SATAKE Hot-Balloon in the Real World

**Shiro Nakahara** , Dokkyo Medical Univ Saitama Medical Ctr, Saitama, Japan; Hiroshi Sohara, Shonan Tobu General Hosp, Kanagawa, Japan; Yoshinori Nakamura, Osaki Hosp Tokyo Heart Ctr, Tokyo, Japan; Hiro Yamasaki, Univ of Tsukuba, Ibaraki, Japan; Yukihiko Yoshida, Nagoya Dai-ni Red Cross Hosp, Aichi, Japan; Tsunesuke Kohno, Nagano Medical Co-Op Nagano Central Hosp, Nagano, Japan; Akira Shimane, Hyogo Prefectural Himeji Cardiovascular Ctr, Hyogo, Japan; Yasushi Miyauchi, Nippon Medical Sch Chiba Hokuso Hosp, Chiba, Japan; Yoshifumi Okano, Tokyo Metropolitan Health and Treament Corp Ohkubo Hosp, Tokyo, Japan; Keisuke Shioji, Kishiwada City Hosp, Osaka, Japan; Satoki Fukae, Nagasaki Univ Hosp, Nagasaki, Japan; Shutaro Satake, Hayama Heart Ctr, Kanagawa, Japan; Tomoya Ozawa, Shiga Univ of Medical Science Hosp, Shiga, Japan; Atsushi Kobori, Kobe City Medical Ctr General Hosp, Hyogo, Japan; Toru Kamijima, Dokkyo Medical Univ, Tochigi, Japan; Masahiro Muto, Hamamatsu Medical Ctr, Shizuoka, Japan; Koichi Nagashima, Nihon Univ Sch of Med, Tokyo, Japan; Shigeto Naito, Gunma Prefectural Cardiovascular Ctr, Gunma, Japan; Tatsuya Usui, Japanese Red Cross Society Nagano Hosp, Nagano, Japan; Masahide Harada, Fujita Health Univ Hosp, Aichi, Japan; Takeshi Sasaki, Natl Hosp Organization Disaster Medical Ctr, Tokyo, Japan; Tetsuya Watanabe, Yao Municipal Hosp, Osaka, Japan; Mitsuhiro Fukata, Kyushu Univ Hosp, Fukuoka, Japan; Teiichi Yamane, Jikei Univ Sch of Med, Tokyo, Japan; Kageyuki Oba, Tomishiro Central Hosp, Okinawa, Japan; Masaomi Kimura, Hirosaki Univ Graduate Sch of Med, Aomori, Japan; Hisashi Murakami, Japan Community Health Care Organization Chukyo Hosp, Aichi, Japan; Hirotaka Sugiura, Kosei-ren Niigata Medical Ctr Hosp, Niigata, Japan; Kengo Kusano, Natl Cerebral and Cardiovascular Ctr, Osaka, Japan; Yasuya Inden, Nagoya Univ Graduate Sch of Med, Aichi, Japan; Kazutaka Aonuma, Univ of Tsukuba, Ibaraki, Japan; HARVEST study (Hot-bAlloon pulmonary VEin isolation regiSTry Study) Investigators

7:45 AM

Discussion

7:48 AM

Optimal Interruption Time of Dabigatran Per OS to Ablation (O-A Time) in Patients With Atrial Fibrillation: Integrated Analysis From 2 Randomized Controlled Clinical Trials

**Akira Kimata** , Hiro Yamasaki, Tomohiro Ohigashi, Masahiko Gosho, Miyako Igarashi, Yukio Sekiguchi, Akihiko Nogami, Masaki Ieda, Univ of Tsukuba, Tsukuba, Japan; Hugh Calkins, Johns Hopkins Medical Insts, Baltimore, MD; Kazutaka Aonuma, Univ of Tsukuba, Tsukuba, Japan

7:56 AM

Discussion

7:59 AM

Gene Sequencing to Identify Rare Pathogenic Variants Conferring Increased Risk of Adult-Onset Sudden Cardiac Death

**Amit V Khera** , Massachusetts General Hosp, Boston, MA; Heather Mason-Suares, Partners HealthCare, Cambridge, MA; Deanna Brockman, Massachusetts General Hosp, Boston, MA; Minxian Wang, Broad Inst of MIT and Harvard, Cambridge, MA; Martin VanDenburgh, Brigham and Women's Hosp, Boston, MA; Ozlem Senol-Cosar, Partners HealthCare, Cambridge, MA; Candace Patterson, Broad Inst of MIT and Harvard, Cambridge, MA; Christopher Newton-cheh, Massachusetts General Hosp, Lexington, MA; Seyedeh Maryam Zekavat, Yale Sch of Med, Newton, MA; Julie Pester, Daniel Chasman, Brigham and Women's Hosp, Boston, MA; Christopher Kabrhel, Massachusetts General Hosp, Boston, MA; Majken K Jensen, Harvard Chan Sch Public Health, Boston, MA; Joann E Manson, Harvard Medical Sch, Boston, MA; J. M. Gaziano, Brigham and Women's Hosp, Boston, MA; Kent D Taylor, LA Biomedical Res Inst, Torrance, CA; Nona Sotoodehnia, Univ of Washington, Seattle, WA; Wendy S Post, Johns Hopkins Univ, Baltimore, MD; Stephen S Rich, Univ of Virginia, Charlottesville, VA; Jerome I Rotter, LA Biomedical Res Inst, Torrance, CA; Eric Lander, Broad Inst of MIT and Harvard, Boston, MA; Heidi Rehm, Massachusetts General Hosp, Boston, MA; Kenney Ng, IBM Res, Cambridge, MA; Anthony Andrew Philippakis, Broad Inst, Cambridge, MA; Matthew Lebo, Partners Personalized Med, Cambridge, MA; Christine M Albert, Brigham and Women's Hosp, Boston, MA; Sekar Kathiresan, Verve Therapeutics, Cambridge, MA

8:07 AM

Discussion

8:10 AM

Novel Genotype and Mutation-Specific Risk Prediction Model for Life-Threatening Arrhythmic Events in Women With Long-QT Syndrome

**Ilan Goldenberg** , Ayhan Yoruk, Valentina Kutyifa, Anita Chen, Scott McNitt, Univ of Rochester, Rochester, NY; David T. Huang, Univ Rochester Medical Ctr, Rochester, NY; Arwa Younis, Univ of Rochester, Rochester, NY; Nona Sotoodehnia, Univ of Washington, Seattle, WA; Wojciech Zareba, Univ of Rochester Medical Ctr, Rochester, NY

8:20 AM

Increased Nocturnal Respiratory Rate Predicts ICD Inefficacy: A Predefined Prospective EU-CERT-ICD Substudy

Michael Dommasch, Alexander Steger, Technical Univ of Munich, Munich, Germany; Markus Harden, Univ of Göttingen Medical Ctr, Göttingen, Germany; Alexander Mueller, Katharina M Huster, Technical Univ of Munich, Munich, Germany; Andrzej Lubinski, Medical Univ of Lodz WAM Hosp, Lodz, Poland; Panayota Flevari, Attikon Univ Hosp, Athens, Greece; Christian Sticherling, Univ Hosp, Univ of Basel, Basel, Switzerland; Rik Willems, Univ Hosp, KU Leuven, Leuven, Belgium; Béla Merkely, Semmelweis Univ Heart Ctr, Budapest, Hungary; Heikki Huikuri, Oulu Univ Hosp, Oulu, Finland; Axel Bauer, Medical Univ of Innsbruck, Innsbruck, Austria; Petra Barthel, Karl-Ludwig Laugwitz, Technical Univ of Munich, Munich, Germany; Marek Malik, Imperial Coll, London, London, United Kingdom; Tim Friede, Markus Zabel, Univ of Göttingen Medical Ctr, Göttingen, Germany; **Georg Schmidt** , Technical Univ of Munich, Munich, Germany

8:28 AM

Discussion

# Featured Science

## FS.AOS.01 - Featured Science Population Science

#### 103B

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Neha Pagidipati, Durham, NC

7:15 AM

Genetically Reduced IL-6 Attenuates Cardiovascular Disease Risk in Clonal Hematopoiesis

**Alexander G Bick** , James Pirruccello, Massachusetts General Hosp, Boston, MA; Peter Libby, Brigham and Women's Hosp, Boston, MA; Sekar Kathiresan, Verve Therapeutics, Cambridge, MA; Pradeep Natarajan, Massachusetts General Hosp, Boston, MA

7:25 AM

Discussion

7:30 AM

Cost-Effectiveness of Icosapent Ethyl in REDUCE-IT

**William S Weintraub** , MedStar Washington Hosp Ctr, Washington, DC; Deepak L Bhatt, Brigham and Women's Hosp, Boston, MA; Zugui Zhang, Christiana Care Health System, Newark, DE; Sarahfaye F Dolman, Cheng Zhang, MedStar Washington Hosp Ctr, Washington, DC; William E Boden II, VA Boston Healthcare System, Boston, MA; Adam P Bress, Univ of Utah, Salt Lake City, UT; Jordan B King, Univ of Utah, Salt Lake Cty, UT; Philippe Gabriel Steg, Hop Bichat, Paris, France; Eliot A Brinton, Utah Lipid Ctr, Salt Lake City, UT; Terry A Jacobson, Emory Univ, Atlanta, GA; Jean Claude Tardif, Montreal Heart Institue, Montreal, QC, Canada; Christie M Ballantyne, Baylor Coll Med, Houston, TX; Paul Kolm, MedStar Washington Hosp Ctr, Washington, DC

7:40 AM

Discussion

7:45 AM

Fine Particulate Matter Triggers Out-of-Hospital Cardiac Arrest of Cardiac Origin: A Nationwide Registry-Based Study in Japan

**Sunao Kojima** , Kawasaki Medical Sch, Okayama, Japan; Takehiro Michikawa, Toho Univ, Tokyo, Japan; Kunihiko Matsui, Kumamoto Univ Hosp, Kumamoto, Japan; Hisao Ogawa, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Shin Yamazaki, Hiroshi Nitta, Akinori Takami, Natl Inst for Environmental Studies, Tsukuba, Japan; Kayo Ueda, Kyoto Univ Graduate Sch of Global Environmental Studies, Kyoto, Japan; Yoshio Tahara, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Naohiro Yonemoto, Natl Ctr of Neurology and Psychiatry, Kodaira, Japan; Hiroshi Nonogi, Shizuoka General Hosp, Shizuoka, Japan; Ken Nagao, Nihon Univ Hosp, Tokyo, Japan; Takanori Ikeda, Toho Univ Faculty of Med, Tokyo, Japan; Naoki Sato, Kawaguchi Cardiovascular and Respiratory Hosp, Kawaguchi, Japan; Hiroyuki Tsutsui, Kyushu Univ, Fukuoka, Japan; Japanese Circulation Society with Resuscitation Science Study (JCS-ReSS) Group

7:55 AM

Discussion

8:00 AM

Population Impact of Generic Valsartan Recall

**Cynthia Jackevicius** , Western Univ of Health Sciences, Los Angeles, CA; Harlan M Krumholz, Yale Univ, New Haven, CT; Alice Chong, Maria Koh, ICES, Toronto, ON, Canada; Aya Ozaki, Western Univ of Health Sciences, Pomona, CA; Peter Austin, ICES, Toronto, ON, Canada; Jacob A Udell, Women's Coll Hosp, Toronto, ON, Canada; Dennis T Ko, ICES, Toronto, ON, Canada

8:10 AM

Discussion

8:15 AM

Effectiveness of Systematic Echocardiographic Screening for Rheumatic Heart Disease in Nepalese School Children: Cluster Randomized Comparison

Prahlad Karki, Surendra Uranw, Santosh Bastola, Rajan Mahto, BP Koirala Inst of Health Sciences, Dharan, Nepal; Nikesh Shrestha, Neuro Cardio and Multispeciality Hosp, Dharan, Nepal; Dhungana Sahadeb, Noble Medical Coll Teaching Hosp and Res Ctr, Biratnagar, Nepal; Keshar Gurung, Neuro Cardio and Multispeciality Hosp, Biratnagar, Nepal; Naveen Pandey, Krishna Agrawal, Prashant Shah, BP Koirala Inst of Health Sciences, Dharan, Nepal; Martina Rothenbühler, Univ of Bern, Bern, Switzerland; Peter Juni, St. Michael's Hosp - Applied He, Toronto, ON, Canada; **Thomas Pilgrim** , Univ of Bern, Bern, Switzerland

8:25 AM

Discussion

# Frontiers in Science

## EA.FIS.599 - Arrhythmia Research Summit: Translational Insights into AF

#### 119AB

### Saturday, November 16, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Glenn I FISHMAN, New York, NY

7:15 AM

Moderator

Vadim V FEDOROV, Columbus, OH

7:15 AM

Keynote: Putting It All Together for AF: Bench to Bedside

Ulrich Schotten, Maastricht

7:25 AM

Q&A

7:27 AM

Genetic Discovery in AF

Patrick Ellinor, Boston, MA

7:32 AM

Q&A

7:33 AM

Development, Regeneration, and AF

James Martin, Houston, TX

7:38 AM

Q&A

7:39 AM

New AF Mechanisms from GWAS Findings

Jonathan D SMITH, Cleveland, OH

7:44 AM

Q&A

7:45 AM

Role of the inflammasome in AF: New evidence for targeting inflammation?

Na Li, Houston, TX

7:50 AM

Q&A

7:51 AM

Novel insights into atrial remodeling

Jean-baptiste Guichard, Saint-priest-en-jarez, France

7:56 AM

Q&A

7:57 AM

Mechanisms underlying AF: Triggers, Rotors, Substrate and More

Sanjay Dixit, Wynnewood, PA

8:02 AM

Q&A

8:03 AM

What Can Atrial Structure Tell Us About Atrial Electrical Activity?

Elaine Wan, New York, NY

8:08 AM

Q&A

8:14 AM

Q&A

8:15 AM

Multi-modality integration to improve AF therapy

Rod Passman, Chicago, IL

8:20 AM

Q&A

8:21 AM

Can Genomics Inform Atrial Fibrillation Risk Prediction and Motivate Behavior Change?

Emelia Benjamin, Brookline, MA

8:26 AM

Q&A

# Cardiovascular Seminar

## CC.CVS.01 - State of the Art Cardiovascular Care

#### 118B

### Saturday, November 16, 2019, 8:00 AM - 5:15 PM

8:00 AM

Update in Mitral Valve Intervention: MVIV, COAPT, MITRA-FR

Mayra Guerrero, Evanston, IL

8:30 AM

Updates in Peripheral Vascular Disease

Nick J Leeper, Stanford, CA

8:45 AM

2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease, Prevention, Risk Modification, and Outcomes

Roger S Blumenthal, Baltimore, MD

9:00 AM

Advances in Women and Heart Disease After Going Red for 15 Years

Annabelle Santos Volgman, Chicago, IL

9:15 AM

2019 Guidelines for Management of Acute Stroke

Qingyang Kristy Yuan, San Francisco, CA

9:30 AM

Advances in Cholesterol: Guidelines 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol

Lynne T Braun, Chicago, IL

10:00 AM

What do I need to know about the care of adults with congenital heart disease?

Karen Stout, Seattle, WA

10:30 AM

Cardiovascular genetics: is it finally ready for prime time?

Kiran Musunuru, Philadelphia, PA

10:45 AM

The Apple Heart Study and Beyond

Marco Valentin Perez, San Jose, CA

11:00 AM

Updates in Device Therapy

Mina K Chung, Cleveland, OH

11:15 AM

Updates in Atrial Fibrillation Ablation and Management: ALL-IN, HELP-AF, PRAGUE-17

Paul J Wang, Palo Alto, CA

11:30 AM

Biology of Adversity

Michelle A Albert, San Francisco, CA

11:45 AM

Managing Hypertension: Latest Trials HOPE 4 and MODERATO

Jordana Cohen, Philadelphia, PA

1:00 PM

Latest Advances in Acute Coronary Syndromes: AUGUSTUS ACS, ISAR-REACT 5, Evolocumab, and BETonMACE

Connie N Hess, Aurora, CO

1:15 PM

Latest Advances in Coronary Artery Stenting: TWILIGHT, ONYX One, and EVOLVE

Roxana Mehran, New York, NY

1:30 PM

What is New in Revascularization and Coronary Intervention: COMPLETE and EXCEL

Sunil V Rao, Durham, NC

2:00 PM

How Clinical Trials are Transforming Cardiovascular Care

Robert A Harrington, Stanford, CA

2:45 PM

New Advances in Heart Failure Treatment

Nancy K Sweitzer, Tucson, AZ

3:00 PM

Advances in Stem Cell

Joseph C Wu, Stanford, CA

3:45 PM

Sudden Death and Ventricular Tachycardia Trials: PREVENTION-ACHD; DAPA EU-CERT-ICD

Wendy S Tzou, Aurora, CO

4:00 PM

New Advances in Cardiovascular Imaging

Robert J Gropler, Saint Louis, MO

4:15 PM

ISCHEMIA Trial Results

David J Maron, Stanford, CA

# Main Event

## CS.ME.621 - Opening & Cutting Edge in CV Medicine: Genes to Behavior Change in the 21st Century

#### Main Event I

### Saturday, November 16, 2019, 8:30 AM - 10:15 AM

9:00 AM

Moderator

Jessica Mega, Portola Valley, CA

9:00 AM

Moderator

Donald M Lloyd-jones, Chicago, IL

9:00 AM

Moderator

Manesh R Patel, Durham, NC

9:00 AM

Welcome & Opening Remarks

Donald M Lloyd-jones, Chicago, IL

9:15 AM

Gene Therapy in the CRISPR Era

Elizabeth M McNally, Chicago, IL

9:27 AM

Contrast-Enhanced Ultrasound: Novel Imaging and Therapeutic Delivery Approaches

Paul A Grayburn, Dallas, TX

9:39 AM

RNA-Targeted Therapeutics in Cardiovascular Disease

Joseph L Witztum, La Jolla, CA

9:51 AM

A.I. for Cardiovascular (Imaging to Decision Making)

Damini Dey, Los Angeles, CA

10:03 AM

Behavioral Economics and Unhealthy Habits

Asch David, Philadelphia, PA

# Abstract Oral Session

## EP.AOS.570 - Big Data Approaches for Cardiovascular Risk

#### 201C

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Ann Marie Navar, Durham, NC

9:00 AM

Moderator

Salim Hayek, Ann Arbor, MI

9:00 AM

Pooled Cohort Equations-Derived Heart Failure Risk Score Predicts Cardiovascular And All-Cause Mortality In U.S. Adults: The NHANES III Follow-Up Study

**Alexander C. Razavi** , Camilo Fernandez Alonso, Tulane Univ Sch of Public Health and Tropical Med; Tulane Univ Sch of Med, New Orleans, LA; Tanika N. Kelly, Tulane Univ Sch of Public Health and Tropical Med, New Orleans, LA; Jiang He, Tulane Univ Sch of Public Health and Tropical Med; Tulane Univ Sch of Med, New Orleans, LA; Kaitlin S. Potts, Tulane Univ Sch of Public Health and Tropical Med, New Orleans, LA; Seamus P. Whelton, Johns Hopkins Univ Sch of Med, Baltimore, MD; Lydia A Bazzano, Tulane Univ Sch of Public Health and Tropical Med; Tulane Univ Sch of Med, New Orleans, LA

9:10 AM

Q & A

9:15 AM

Deep Neural Networks Can Predict 1-Year Mortality Directly From ECG Signal, Even When Clinically Interpreted as Normal

**Sushravya M Raghunath** , Alvaro Ulloa Cerna, Linyuan Jing, David vanMaanen, Geisinger, Danville, PA; Joshua Victor Stough, Bucknell Univ, Lewisburg, PA; Dustin Hartzel, Joseph Leader, H Lester Kirchner, Geisinger, Danville, PA; Christopher Good, Medicor Associates, Inc, Erie, PA; Aalpen Patel, Geisinger, Danville, PA; Brian P Delisle, Univ of Kentucky, Lexington, KY; Amro Alsaid, Dominik Beer, Christopher M Haggerty, Brandon K Fornwalt, Geisinger, Danville, PA

9:25 AM

Q & A

9:30 AM

Risk Variation Within Very High-risk Group Among Patients With Atherosclerosis Cardiovascular Disease: The Atherosclerosis Risk in Communities (ARIC) Study

**Ye Jin Mok** , Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Shoshana H Ballew, Johns Hopkins Bloomberg, Baltimore, MD; Brandon Stacey, Wake Forest Univ Sch of Med, Winston-Salem, NC; Joseph Rossi, Univ of North Carolina Sch of Med, Chapel Hill, NC; Silvia Koton, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Anna Kucharska-Newton, Univ North Carolina, Chapel Hill, NC; Patricia P Chang, Univ of North Carolina, Chapel Hill, NC; Josef Coresh, Johns Hopkins Sph Welch Ctr, Baltimore, MD; Wayne D Rosamond, Univ NC Sch Public Hlth, Chapel Hill, NC; Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD

9:40 AM

Q & A

9:45 AM

Integration Of A Genome-wide Polygenic Score With ACC/AHA Pooled Cohorts Equation In Prediction Of Coronary Artery Disease Events In >285,000 Participants

**George Hindy** , Krishna Aragam, Mark Chaffin, Broad Inst, Cambridge, MA; Marju Orho-Melander, Olle Melander, Lund Univ, Malmö, Sweden; Amit V Khera, Massachusetts General Hosp, Cambridge, MA; Sekar Kathiresan, Verve Therapeutics, Cambridge, MA

9:55 AM

Q & A

10:10 AM

Q & A

# Abstract Oral Session

## CM.AOS.487 - Risk Factors and Biomarkers Associated with CVD in Cardiometabolic Disease

#### 204AB

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Lipoprotein Insulin Resistance Score, but Not Traditional Measures, Discriminates Patients With Pre-operative Metabolic Syndrome at up to One Year Following Bariatric Surgery

**Ruina Zhang** , BingXue Lin, Manish Parikh, Edward A Fisher, Jeffrey S Berger, Jose O Aleman, Sean P Heffron, NYU Langone Medical Ctr, NYU Sch of Med, New York, NY

9:10 AM

Q & A

9:15 AM

Close Association Between Circulating High-sensitivity Cardiac Troponin I and Presence Of Metabolic Syndrome in the General Population

**Tomonori Sugiura** , Nagoya City Univ Graduate Sch of Medical Sciences, Nagoya, Japan; Yasuaki Dohi, Nagoya Gakuin Univ, Nagoya, Japan; Hiroyuki Takase, Enshu Hosp, Nagoya, Japan; Sumiyo Yamashita, Tatsuya Mizoguchi, Yoshihiro Seo, Nagoya City Univ Graduate Sch of Medical Sciences, Nagoya, Japan; Satoshi Fujii, Asahikawa Medical Univ, Asahikawa, Japan; Nobuyuki Ohte, Nagoya City Univ Graduate Sch of Medical Sciences, Nagoya, Japan

9:25 AM

Q & A

9:30 AM

Relationship Between Baseline Cardiac Biomarkers and Cardiovascular Death or Hospitalization for Heart Failure in DECLARE-TIMI 58

**Thomas Alexander Zelniker** , David A Morrow, TIMI Study Group, Brigham and Women's Hosp and Harvard Medical Sch, Boston, MA; Ofri Mosenzon, Hadassah Hebrew Univ Hosp, Jerusalem, Israel; Erica Goodrich, Sabina A Murphy, Deepak L Bhatt, TIMI Study Group, Brigham and Women's Hosp and Harvard Medical Sch, Boston, MA; Lawrence A Leiter, Univ of Toronto, Toronto, ON, Canada; Darren K McGuire, Univ of Texas Southwestern Medical Ctr, Dallas, TX; John Ph Wilding, Univ of Liverpool, Liverpool, United Kingdom; Ingrid Ami Gause-Nilsson, Anna Maria Langkilde, AstraZeneca, Mölndal, Sweden; Itamar Raz, Hadassah Hebrew Univ Hosp, Tel Aviv, Israel; Marc S Sabatine, TIMI Study Group, Brigham and Women's Hosp and Harvard Medical Sch, Boston, MA; Stephen D Wiviott, TIMI Study Group, Brigham and Women's Hosp and Harvard Medical Sch, Wellesley, MA

9:40 AM

Q & A

9:45 AM

Growth Differentiation Factor 15 and Mortality in Prediabetic Patients With Suspected or Known Coronary Artery Disease: From the ANOX Study

**Hiromichi Wada** , Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan; Masahiro Suzuki, Natl Hosp Organization Saitama Hosp, Wako, Japan; Morihiro Matsuda, Natl Hosp Organization Kure Medical Ctr and Chugoku Cancer Ctr, Kure, Japan; Yoichi Ajiro, Natl Hosp Organization Yokohama Medical Ctr, Yokohama, Japan; Tsuyoshi Shinozaki, Natl Hosp Organization Sendai Medical Ctr, Sendai, Japan; Satoru Sakagami, Natl Hosp Organization Kanazawa Medical Ctr, Kanazawa, Japan; Kazuya Yonezawa, Natl Hosp Organization Hakodate Natl Hosp, Hakodate, Japan; Masatoshi Shimizu, Natl Hosp Organization Kobe Medical Ctr, Kobe, Japan; Junichi Funada, Natl Hosp Organization Ehime Medical Ctr, Toon, Japan; Takashi Takenaka, Natl Hosp Organization Hokkaido Medical Ctr, Sapporo, Japan; Yukiko Morita, Natl Hosp Organization Sagamihara Natl Hosp, Sagamihara, Japan; Toshihiro Nakamura, Natl Hosp Organization Kyushu Medical Ctr, Fukuoka, Japan; Kazuteru Fujimoto, Natl Hosp Organization Kumamoto Medical Ctr, Kumamoto, Japan; Hiromi Matsubara, Natl Hosp Organization Okayama Medical Ctr, Okayama, Japan; Toru Kato, Natl Hosp Organization Tochigi Medical Ctr, Utsunomiya, Japan; Takashi Unoki, Daisuke Takagi, Kyohma Wada, Miyaka Wada, Moritake Iguchi, Nobutoyo Masunaga, Mitsuru Ishii, Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan; Kazuhiko Kotani, Jichi Medical Univ, Shimotsuke, Japan; Mitsuru Abe, Masaharu Akao, Koji Hasegawa, Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan

9:55 AM

Q & A

10:00 AM

Vascular Endothelial Growth Factor D and Mortality in Patients With Diabetes and Stable Coronary Heart Disease: From the ANOX Study

**Hiromichi Wada** , Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan; Masahiro Suzuki, Natl Hosp Organization Saitama Hosp, Wako, Japan; Morihiro Matsuda, Natl Hosp Organization Kure Medical Ctr and Chugoku Cancer Ctr, Kure, Japan; Yoichi Ajiro, Natl Hosp Organization Yokohama Medical Ctr, Yokohama, Japan; Tsuyoshi Shinozaki, Natl Hosp Organization Sendai Medical Ctr, Sendai, Japan; Satoru Sakagami, Natl Hosp Organization Kanazawa Medical Ctr, Kanazawa, Japan; Kazuya Yonezawa, Natl Hosp Organization Hakodate Natl Hosp, Hakodate, Japan; Masatoshi Shimizu, Natl Hosp Organization Kobe Medical Ctr, Kobe, Japan; Junichi Funada, Natl Hosp Organization Ehime Medical Ctr, Toon, Japan; Takashi Takenaka, Natl Hosp Organization Hokkaido Medical Ctr, Sapporo, Japan; Yukiko Morita, Natl Hosp Organization Sagamihara Natl Hosp, Sagamihara, Japan; Toshihiro Nakamura, Natl Hosp Organization Kyushu Medical Ctr, Fukuoka, Japan; Kazuteru Fujimoto, Natl Hosp Organization Kumamoto Medical Ctr, Kumamoto, Japan; Hiromi Matsubara, Natl Hosp Organization Okayama Medical Ctr, Okayama, Japan; Toru Kato, Natl Hosp Organization Tochigi Medical Ctr, Utsunomiya, Japan; Takashi Unoki, Daisuke Takagi, Kyohma Wada, Miyaka Wada, Moritake Iguchi, Nobutoyo Masunaga, Mitsuru Ishii, Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan; Kazuhiko Kotani, Jichi Medical Univ, Shimotsuke, Japan; Mitsuru Abe, Masaharu Akao, Koji Hasegawa, Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan

10:10 AM

Q & A

# Abstract Oral Session

## EA.AOS.495 - Samuel A. Levine Early Career Clinical Investigator Award Competition

#### 107AB

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Eldrin F Lewis, Boston, MA

9:00 AM

Moderator

Frank Brozovich, Rochester, MN

9:00 AM

Does Endothelial Function Influence Exercise Physiology and Inducible Myocardial Ischemia in Patients With Microvascular Angina?

**Haseeb Rahman** , Ozan Demir, St Thomas' Hosp, London, United Kingdom; Matthew Ryan, St Thomas Hosp, London; Howard Ellis, St Thomas' Hosp, London, United Kingdom; Andrew Webb, Kings Coll, London; Amedeo Chiribiri, St Thomas' Hosp, London, United Kingdom; Divaka Perera, St. Thomas' Hosp, London, United Kingdom

9:10 AM

Q & A

9:15 AM

Does Race Influence Decision-making for Advanced Heart Failure Therapies?

**Khadijah Breathett** , Erika Yee, Univ of Arizona, Tucson, AZ; Natalie Pool, Univ of Arizona, Tucson; Megan Hebdon, Univ of Arizona, Tucson, AZ; Janice Crist, Univ of Arizona, Tucson; Shannon Knapp, Ashley Larsen, Sade Solola, Univ of Arizona, Tucson, AZ; Luis Luy, Univ of Rochester, Rochester, NY; Kathryn Herrera-Theut, Univ of Arizona, Tucson; Leanne Zabala, Jeff Stone, Marylyn McEwen, Univ of Arizona, Tucson, AZ; Elizabeth Calhoun, Nancy Sweitzer, UNIVERSITY OF ARIZONA, Tucson, AZ

9:25 AM

Q & A

9:30 AM

Genetic Susceptibility to Atrial Fibrillation is Associated With Left Atrial Electrical Remodeling and Adverse Post-ablation Outcome

**Geoffrey R Wong** , Chrishan Jospeh Nalliah, Geoffrey Lee, Royal Melbourne Hosp, Melbourne, Australia; Alex Voskoboinik, Sandeep Prabhu, Alfred Hosp, Melbourne, Australia; Ramanathan Parameswaran, Royal Melbourne Hosp, Melbourne, Australia; Hari Sugumar, Alfred Hosp, Melbourne, Australia; Robert Anderson, Royal Melbourne Hosp, Melbourne, Australia; Liang-Han Ling, Alfred Hosp, Melbourne, Australia; Renee Johnson, Victor Chang Cardiac Res Inst, Sydney, Australia; Prashanthan Sanders, Univ of Adelaide, Norwood, SA, Australia; Peter Kistler, The Alfred Hosp, Melbourne, Australia; Diane Fatkin, Victor Chang Cardiac Res Inst, Darlinghurst, Australia; Jonathan Kalman, Dept of Cardiology, Melbourne, Australia

9:40 AM

Q & A

9:45 AM

Supar as a Prognostic and Therapeutic Target in Post-procedural Acute Kidney Injury

**Salim Hayek** , Univ of Michigan, Ann Arbor, MI; David Leaf, Brigham and Women's Hosp, Boston, MA; Ayman Samman Tahhan, Mohamad Raad, Emory Univ, Atlanta, GA; Shreyak Sharma, Brigham and Women's Hosp, Boston, MA; Sushrut Waikar, Sanja Sever, Massachusetts General Hosp, Boston, MA; Xuexiang Wang, Rush Univ Medical Ctr, Chicago, IL; Ranadheer Dande, Rush Univ, Chicago, IL; Changli Wei, Rush Univ, Chicagol, IL; Arshed A Quyyumi, Emory Univ, Atlanta, GA; Jochen Reiser, Rush Univ, Chicago, IL

9:55 AM

Q & A

10:00 AM

Transvalvular Flow Rate Determines Prognostic Value of Aortic Valve Area in Aortic Stenosis

**Mayooran Namasivayam** , Wei He, Timothy W Churchill, Romain Capoulade, Shiying Liu, Hang Lee, Jacqueline S Danik, Michael H Picard, Robert A Levine, Judy Hung, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA

10:10 AM

Q & A

# Abstract Oral Session

## ST.AOS.357 - Stroke Complications After Intervention

#### 120A

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Ilana M Ruff Treiber, Chicago, IL

9:00 AM

Total and Cause-Specific Mortality in Patients Who Had a Perioperative Stroke Following Cardiovascular Procedures

**Khaled Al-Robaidi** , Univ of Alabama at Birmingham, Birmingham, AL; Qasem Alshaer, Emory Univ Hosp, Atlanta, GA; Laith Alhuneafat, Nada Alrifai, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Samir Alghazawi, Univeristy of Pittsburgh Medical Ctr, Pittsburgh, PA; Parthasarathy Thirumala, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA

9:10 AM

Q & A

9:15 AM

Hospital Readmission in Perioperative Stroke Patients After Invasive Cardiac Procedures: California State Inpatient Database Study

**Nada Alrifai** , Univeristy of Pittsburgh Medical Ctr, Pittsburgh, PA; Laith Alhuneafat, Allegheny Health Network, Pittsburgh, PA; Khaled Al-Robaidi, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Parthasarathy Thirumala, Univ of Pittsburgh Medic, Pittsburgh, PA

9:25 AM

Q & A

9:30 AM

A Comparison of Outcomes Following Left Atrial Appendage Occlusion With Watchman Device Stratified by Post-Procedure Antithrobotic Regimens

**Shiva P Ponamgi** , Mayo Clinic, Austin, MN; Majd El-Harasis, Vanderbilt Univ Medical Ctr, Nashville, TN; Robert Ward, Christopher V Desimone, Stephen English, Thomas Michael Munger, Jonathan Graff-Radford, Mayo Clinic, Rochester, MN; Alejandro A Rabinstein, Mayo Clinic Neurology, Rochester, MN; Samuel Asirvatham, Mayo Fndn, Rochester, MN; David R Holmes, Mayo Clinic, Rochester, MN

9:40 AM

Q & A

9:45 AM

Asymptomatic Cerebral Infarction May be a Prognostic Marker in Patients After Cardiac Catheterization

**Kenji Yamaji** , Kindai Univ. Faculty of Med, Osakasayama, Japan; Yoshitaka Iwanaga, Kindai Univ Faculty of Medici, Osakasayama, Japan; Toru Takase, Kindai university, Osakasayama, Japan; Masafumi Ueno, Kindai Univ, Osakasayama, Japan; Kazuhiro Kobuke, Kindai Univ Faculty of Med, Osakasayama, Japan; Takashi Kurita, Kinki Univ Sch of Med, Osaka-Sayama, Japan; Shunichi Miyazaki, Saiseikai Tondabayashi Hosp, Tondabayashi, Japan

9:55 AM

Q & A

10:00 AM

Prevalence of Stroke and Its Clinical Implication in Patients With Percutaneous Mechanical Circulatory Support Devices: A National Perspective

**Mohit Pahuja** , Wayne State Univ, Detroit, MI; Omar Chehab, Wayne State Univ-DMC, Detroit, MI; Ahmed Yassin, Tushar Mishra, Detroit Medical Ctr/Wayne State Univ, Detroit, MI; Aman Handa, Wayne State Univ, Detroit, MI; Sagar Ranka, John H Stroger Hosp of Cook Cou, Chicago, IL; Hossam Abubakar, Tanvir Khosla, Wayne State Univ, Detroit, MI; Tomo Ando, Detroit Medical Ctr, Detroit, MI; Navin K Kapur, Tufts Medical Ctr, Hanover, MA

10:10 AM

Q & A

# Abstract Oral Session

## CH.AOS.501 - Young Hearts Early Career Investigator Competition and Rashkind Lecture

#### 113BC

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Antonio G Cabrera, Houston, TX

9:00 AM

Moderator

Elizabeth D Blume, Boston, MA

9:25 AM

Q & A

9:30 AM

Heart Failure-Related Deaths Through Early Adulthood Among Children Operated for Congenital Heart Disease

**Lydia Wright** , Emory Univ, Atlanta, GA; Matthew Oster, Children's Healthcare of Atlanta, Atlanta, GA; Courtney McCracken, Emory Univ, Atlanta, GA; William T Mahle, Emory, Atlanta, GA; Lazaros Kochilas, Emory Univ, Atlanta, GA; Andreas P Kalogeropoulos, Stony Brook Univ, Stony Brook, NY

9:40 AM

Q & A

9:45 AM

Genetic Variant Burden and Outcomes in Pediatric Cardiomyopathy

**Danielle Burstein** , James W Gaynor, Children's Hosp of Philadelphia, Philadelphia, PA; Heather Griffis, Philadelphia, PA; Alyssa Ritter, Children's Hosp of Philadelphia, Philadelphia, PA; Matthew J O'Connor, Univ of Pennsylvania, Philadelphia, PA; Joseph William Rossano, Children's Hosp of Philadelphia, Haverford, PA; Kimberly Y Lin, Rebecca C Ahrens-Nicklas, Children's Hosp of Philadelphia, Philadelphia, PA

9:55 AM

Q & A

10:00 AM

Impaired Maternal-Fetal Environment is Associated With Increased Mortality After Stage 1 Norwood Procedure for Single Ventricle Heart Disease

**Jill J. Savla** , Children's Hosp of Philadelphia, Philadelphia, PA; Jing Huang, Mary E. Putt, Perelman Sch of Med, Univ of Pennsylvania, Philadelphia, PA; Julie S. Moldenhauer, Children's Hosp of Philadelphia, Philadelphia, PA; Samuel Parry, Perelman Sch of Med, Univ of Pennsylvania, Philadelphia, PA; Samantha Reilly, Olivia Youman, Jack Rychik, Laura Mercer-Rosa, J. William Gaynor, Children's Hosp of Philadelphia, Philadelphia, PA; Steven M. Kawut, Perelman Sch of Med, Univ of Pennsylvania, Philadelphia, PA

10:10 AM

Q & A

# Cardiovascular Seminar

## ST.CVS.444 - Bridging the Gap: Community-Based Interventions to Address Disparities in Stroke

#### 118A

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Cheryl Bushnell, Winston Salem, NC

9:15 AM

Interventions to Address Disparities in Health Literacy and Stroke Symptom Recognition

Olajide Williams, New York, NY

9:40 AM

Interventions to Reduce Disparities in Recurrent Stroke Risk

Amytis Towfighi, Los Angeles, CA

9:50 AM

Interventions for Community Integration Across Diverse Populations

Barbara J Lutz, Hampstead, NC

10:10 AM

Discussion

# Cardiovascular Seminar

## IM.CVS.493 - Cardiometabolic Microvascular Disease- Premature Heart Failure in African American Males

#### 108B

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Marie-Eve Piche, Quebec, QC, Canada

9:00 AM

Moderator

Garth Beache

9:00 AM

Metabolic and Signaling Effects Underlying Ventricular Dysfunction

Daniel P KELLY, Philadelphia, PA

9:15 AM

Populations at Risk - Lessons from the Jackson Heart Study

Ervin R Fox, Jackson, MS

9:30 AM

Imaging Biomarkers and Relation to Clinical Markers for Risk Stratification

Jamieson M Bourque, Charlottesvle, VA

9:45 AM

Cardiometabolic Microvascular Disease and Premature Heart Failure: Disrupting the Progression and Impacting Disparities

Clyde W Yancy Jr., Chicago, IL

10:00 AM

Discussion

# Cardiovascular Seminar

## SA.CVS.344 - Endocarditis: What I Need to Know in 2019

#### 109AB

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Katherine Harrington, Plano, TX

9:00 AM

Moderator

Alina Nicoara, Durham, NC

9:00 AM

Antibiotic Treatment for Native Valve Endocarditis: Drug Treatment Alone Can Succeed!

Brian Blackburn, Stanford, CA

9:15 AM

How to Do the Commando Procedure for Endocarditis: Aortic Root and Mitral Valve Replacement

Y. Joseph Woo, Stanford, CA

9:30 AM

Don't Forget About Valve Repair Options for Endocarditis

Pavan Atluri, Philadelphia, PA

9:45 AM

Sugical Management of Prosthetic Valve Endocarditis After TAVR

Vinod H Thourani, Washington, DC

10:00 AM

Sugical Strategies When Patients Present With Preoperative Stroke

Jennifer Lawton

# Cardiovascular Seminar

## CH.CVS.399 - Genetic Determinants and Outcomes in Congenital Heart Disease

#### 112AB

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Justin P Zachariah, Houston, TX

9:00 AM

Moderator

Seema Mital, Toronto, ON, Canada

9:00 AM

AHA Statement on Genetics in Congenital Heart Disease

Martina Brueckner

9:11 AM

Case Presentation: Gene Positive HCM Case

Swati Choudhry, Houston, TX

9:22 AM

Known and Uncertain Variants in HCM

Carolyn Ho, Boston, MA

9:33 AM

Genetic Determinants of Bicuspid Aortic Valve

Mona Nemer, Ottawa, ON, Canada

9:44 AM

Genetic Attribution in Sudden Unexplained Death in the Young

Michael John Ackerman, Rochester, MN

9:55 AM

Genotype Positive LV Noncompaction and Prognosis

John Jefferies, TN

10:06 AM

Discussion

# Cardiovascular Seminar

## HF.CVS.367 - Mechanical Hemodynamic Support for Cardiogenic Shock in the Modern Era

#### 105AB

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Sofia Carolina Carolina Masri, Seattle, WA

9:00 AM

Moderator

Sandra Chaparro

9:00 AM

Introduction

9:05 AM

Phenotyping of Cardiogenic Shock: Setting the Stage for Tailored Therapies?

Shelley Hall, Dallas, TX

9:17 AM

Which Device for Which Patient: How I Choose

Sean Van Diepen, Edmonton, AB, Canada

9:29 AM

Why You Should Have a Shock Team

Graham C Wong, Vancouver, BC, Canada

9:41 AM

Debate:  
Percutaneous VAD Devices Save Lives in Cardiogenic Shock (PRO)

Navin K KAPUR, Hanover, MA

9:51 AM

Debate: Percutaneous VAD Devices Do NOT Save Lives in Cardiogenic Shock (CON)

Holger Thiele, Leipzig

10:01 AM

Q&A

# Cardiovascular Seminar

## AC.CVS.372 - Meet the Experts: Challenges in STEMI Management

#### 103A

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Venu Menon, Cleveland, OH

9:00 AM

Moderator

Anthony Bavry, Gainesville, FL

9:00 AM

Strategy for PCI in Patient Presenting With STEMI Who has a Prior TAVR

Ravi Subhash Hira, Seattle, WA

9:10 AM

Discussion

9:15 AM

Pharmacological Approach to Patient With Chronic atrial Fibrillation Presenting With STEMI

C GIBSON, Boston, MA

9:25 AM

Discussion

9:30 AM

My Approach to Revascularization in Patients With Out of Hospital Cardiac Arrest and STEMI

Christian Spaulding, Paris, France

9:40 AM

Discussion

9:45 AM

My Approach to Management of SCAD in the Cath Lab

Rajiv Gulati, Rochester, MN

9:55 AM

Discussion

10:00 AM

My Approach to MI With Normal Coronary Arteries

Jacqueline E Tamis-Holland, New York, NY

10:10 AM

Discussion

# Cardiovascular Seminar

## IN.CVS.515 - Meet, Greet and Learn from the Masters in Interventional Cardiology

#### Terrace Ballroom IV

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Roxana Mehran, New York, NY

9:00 AM

Moderator

Dharam Kumbhani, Dallas, TX

9:00 AM

Case of an Elderly Patient With Multiple Comorbidies Presenting With Shock and Severely Complex Anatomy

Ujjwal Rastogi, New York, NY

9:05 AM

Panel Discussion: Table on Vascular Access and Management

Sunil V Rao, Durham, NC

9:05 AM

Panel Discussion: Table on Vascular Access and Management

Ian C Gilchrist, Hershey, PA

9:05 AM

Panel Discussion: Table on Use of Support Devices and Timing

Navin K KAPUR, Hanover, MA

9:05 AM

Panel Discussion: Table on Use of Support Devices and Timing

Ajay Kirtane, New York, NY

9:05 AM

Panel Discussion: Table on Approach to Treatment of the Lesion

Emmanouil S BRILAKIS, Minneapolis, MN

# Cardiovascular Seminar

## CH.CVS.403 - Miniaturization and Task-Shifting of Echocardiography: Promise or Fear?

#### 111AB

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

MARIA DO CARMO Pereira Nunes, Belo Horizonte, Brazil

9:00 AM

Moderator

Amy E Sanyahumbi, Houston, TX

9:00 AM

Training Front Line Obstetrical Sonographers to Diagnose Congenital Heart Disease

maria fernanda biancolini, Buenos Aires, Argentina

9:15 AM

TeleMedicne and Task Shifting for Diagnosis of Heart Disease in Low Resource Settings

Mariana Mirabel, Paris, France

9:30 AM

Focused Ultrasound for Suspected Heart Disease in the Pediatric Emergency Room

Joanna Cohen

9:45 AM

Bedside Echocardiography in the Pediatric Intensive Care Unit: Who and What Toy?

Thomas Conlon, Philadelphia, PA

10:00 AM

Has the Train Left the Station Too Fast? Should We Embrace or Fear Nontraditional Use of Fetal and Pediatric Echo?

Wyman Lai, CA

# Cardiovascular Seminar

## LF.CVS.434 - Nutrition Consensus vs. Controversies: Advising your Patients

#### 201AB

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Jo Ann S Carson, Dallas, TX

9:00 AM

Moderator

Christopher D Gardner, Stanford, CA

9:08 AM

Sodium - Perspective of the Dietary Reference Intakes

Cheryl Anderson, La Jolla, CA

9:21 AM

Eggs - Perspective From American Heart Association

Kristina Petersen, University Park, PA

9:34 AM

Dairy - Perspective of the Dietary Guidelines Advisory Committee

Connie M Weaver, W Lafayette, IN

9:47 AM

Meat - Perspective From EAT-Lancet Commission - Healthy Planetary Diet

Christopher D Gardner, Stanford, CA

10:00 AM

Panel discussion and Audience Q&A

# Cardiovascular Seminar

## HY.CVS.363 - Sleep Disorders and Hypertension

#### 108A

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Elaine M URBINA, Cincinnati, OH

9:00 AM

Moderator

Wistremundo Dones Figueroa, Humacao, PR

9:00 AM

Sleep Apnea, Insomnia and Hypertension

Fernando Stuardo Wyss Sr., Guatemala

9:15 AM

Sleep Waking Disorders and Hypertension

Fernando Lanas, Temuco, Chile

9:30 AM

Obstructive Sleep Apnea and Hypertension in Children

Carissa Marrie Baker Smith, Baltimore, MD

9:45 AM

Sleep Apnea Syndrome, State of Art in Treatment, Which is the Best

Carol Kotliar, Buenos Aires, Argentina

10:00 AM

Sleep Apnea Syndrome, State of Art in Treatment, Which is the Best in Children

Lucelli Yañez, Ciudad de Mexico, D.F., Mexico

# Cardiovascular Seminar

## PH.CVS.481 - State-of-the-Art Update on PAH Clinical Classification, Diagnostics, and Risk Assessment

#### 102AB

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Ioana Preston, Boston, MA

9:00 AM

Moderator

Stephan Rosenkranz, Cologne

9:00 AM

Evidence for the Morbidity of Intermediate mPAP (19-24 mmHg)

Bradley A Maron, Boston, MA

9:13 AM

Rationale for the New World Health Organization Definition and Classification of PAH

Rogerio Souza, Sao Paolo, Brazil

9:26 AM

The Role of Cut-Offs in Hemodynamic Assessment: DPG vs. TPG vs. PVR

Irene M Lang, Vienna

9:39 AM

Pulmonary Veno-occlusive Disease - How Do I Make the Diagnosis and How Do I Treat?

Olivier Sitbon, Le Kremlin Bicetre, France

9:52 AM

Exercise Induced/Associated PH: Does it Exist, is it Relevant?

Rudolf Oliveira, Sao Paulo, Brazil

10:05 AM

Panel

10:05 AM

Panel Participant

Stephan Rosenkranz, Cologne

# Cardiovascular Seminar

## QU.CVS.504 - The Cost of Drugs for My Patients and Me: Pricing, Pre-Authorization, and Co-Pays

#### 202AB

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Emily C Obrien, Durham, NC

9:00 AM

Moderator

Adam P Bress, Salt Lake City, UT

9:00 AM

Big "C" and Little "c": Comparing Cancer to Cardiovascular Drug Development, Approval, Pricing, and Coverage

Nilay D Shah, Rochester, MN

9:10 AM

Up Up and Away? Examples of Pricing (NOAC, ARNI, PCSK9i, and ATTR Drugs)

Cynthia JACKEVICIUS, Los Angeles, CA

9:20 AM

Taking the Pain Out of Pre-Authorization

Jalpa A Doshi, Philadelphia, PA

9:30 AM

Co-Pays and Donut Holes: How to Figure Out Patient Costs in Real-Time, and How They Affect Adherence

Niteesh Kumar Choudhry, Boston, MA

9:40 AM

Summary Discussion on Cardiovascular Drug Pricing

Emily C Obrien, Durham, NC

10:00 AM

Panel Participant

Nilay Shah, Rochester, MN

10:00 AM

Panel Participant

Cynthia JACKEVICIUS, Los Angeles, CA

10:00 AM

Panel Participant

Jalpa A Doshi, Philadelphia, PA

10:00 AM

Panel Participant

Niteesh Kumar Choudhry, Boston, MA

9:50 AM

Case Presententations

10:00 AM

Q & A/Discussion

# Cardiovascular Seminar

## VA.CVS.347 - Vascular Disease in Women: Different Patients or Different Diseases

#### 103C

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Amy West Pollak, Jacksonville, FL

9:00 AM

Moderator

Esther Sh S Kim, Nashville, TN

9:00 AM

PAD in Women: A Distinct Clinical Entity or Variation of the Same?

Amy West Pollak, Jacksonville, FL

9:15 AM

AAA in Women: it's Not All About the Size

Dawn Coleman, Ann Arbor, MI

9:30 AM

Hypertension in Women Across the Lifespan

Nisha I Parikh, San Francisco, CA

9:45 AM

FMD and SCAD: Sisters or Cousins?

Esther Sh S Kim, Nashville, TN

10:00 AM

Panel Discussion

# Early Career

## NR.EC.349 - Publish or Perish? Rules to Live by for Early Career Authors

#### 118C

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Salah Al-Zaiti, Pittsburgh, PA

9:00 AM

Moderator

Kristin Sandau, Saint Paul, MN

9:00 AM

Session Overview

9:02 AM

Importance of Publication

Victoria Dickson, New York, NY

9:14 AM

Picking A Journal

Tiny Jaarsma, Norrkoping, Sweden

9:26 AM

Impact Factor, H-Index, and Alt-Metrics

Sandra Dunbar, Atlanta, GA

9:38 AM

Revise and Resubmit

Debra Moser, Lexington, KY

9:50 AM

Kathleen A. Dracup Early Career Distinguished Award Lecture

9:50 AM

Dracup Lecture

Marjorie Funk, New Haven, CT

# FIT Event

## FIT.01 - Updates in Stroke: Careers & Future Directions in Vascular Neurology

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Saturday, November 16, 2019, 9:00 AM - 9:45 AM

This is not a CME/CE certified session

# Frontiers in Science

## EA.FIS.600 - Arrhythmia Research Summit: Ventricular Arrhythmias and Sudden Cardiac Death: Bench to Bedside

#### 119AB

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Lee L Eckhardt, Madison, WI

9:00 AM

Moderator

Sumeet S Chugh, Los Angeles, CA

9:00 AM

Molecular mechanisms and impact on Patient Care

Christine Albert, Boston, MA

9:10 AM

Q&A

9:12 AM

The genetic architecture of sudden cardiac arrest

Nona Sotoodehnia, Seattle, WA

9:17 AM

Q&A

9:18 AM

Dispersion of Activation and Repolarization for Identifying Reentry-Vulnerable Zones

Elad Anter, Boston, MA

9:23 AM

Q&A

9:24 AM

Computational Modeling and SCD

Jordi Heijman, Maastricht, MD

9:29 AM

Q&A

9:30 AM

Targeting RyR2 for Ventricular Arrhythmias

Bjorn KNOLLMANN, Nashville, TN

9:35 AM

Q&A

9:36 AM

ARVC New Insights

Jeffrey Saffitz, Boston, MA

9:41 AM

Q&A

9:42 AM

Stress, Aging, Alcohol, and Arrhythmias

Xun Ai, Chicago, IL

9:47 AM

Q&A

9:48 AM

Electroporation: Hype or hope for arrhythmia ablation?

Igor R Efimov, Washington, DC

9:53 AM

Q&A

9:54 AM

SCD Resuscitation Innovation in Monitoring

Daniel J Cantillon, Cleveland, OH

9:59 AM

Q&A

10:00 AM

Genomics of Sudden Death

Elizabeth M McNally, Chicago, IL

10:05 AM

Q&A

10:06 AM

Sex-Specific Mechanisms Underlying Ventricular Arrhythmias

Wojciech Zareba, Rochester, NY

10:11 AM

Q&A

10:12 AM

Panel Discussion

# Hybrid

## PR.HB.563 - Socioeconomic Disparities, Humanitarian Crises and Health

#### 204C

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Mahdi O Garelnabi, Lowell, MA

9:00 AM

Moderator

Francine K Welty, Brookline, MA

9:00 AM

Overview

9:05 AM

Providing Medical Services to Syrian Refugees

Michael Chilazi, Baltimore, MD

9:15 AM

Sudan: Impact of Instability on the Health Care System

Mahdi O Garelnabi, Lowell, MA

9:25 AM

Discussion

9:30 AM

Minority Stress, Social Support, and Cardiovascular Risk Factors in Transgender and Gender Nonconforming Persons

**Billy A Caceres** , Kasey Jackman, Columbia Univ, New York, NY; Donald Edmondson, Columbia Univ Medical Ctr, New York, NY; Walter Bockting, Columbia Univ, New York, NY

9:40 AM

Q&A

9:45 AM

Occupations Associated With Poor Cardiovascular Health in Women

**Bede N Nriagu** , Adams A Ako, Conglong Wang, Anneclaire De Roos, Drexel Univ, Philadelphia, PA; Robert B Wallace, Univ Iowa, Iowa City, IA; Matthew A Allison, Univ of California San Diego, La Jolla, CA; Rebecca Seguin, Cornell Univ, New York, NY; Rami Nassir, Univ of California Davis, Davis, CA; Yvonne Michael, Drexel Univ, Philadelphia, PA

9:55 AM

Q&A

10:00 AM

Development of a Community-Engagement Regional Equity Consortium to Address Cardiovascular Disease Disparities in Diverse Communities: The Northeast Health Equity Consortium (NHEC)

**Lenny Lopez** , Univ California San Francisco, San Francisco, CA; Benjamin Perkins, American Heart Association, Waltham, MA; Marcus M McKinney, Assistant Professor, UCONN Sch of Med, Farmington, CT; Sean Cahill, Fenway Health, Boston, MA

10:10 AM

Q&A

# Joint Sessions

## CS.JS.1631 - Cardiometabolic Disorders in Migrant Populations AHA Joint Session with Emirates Cardiac Society

#### 103B

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

10:00 AM

Q&A

# Joint Sessions

## CS.JS.622 - Resuscitation: What Works and What Doesn't Work: Joint Session with AHA and Brazilian Society of Cardiology

#### 121A

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Karl B Kern, Tucson, AZ

9:00 AM

Moderator

Glaucia Maria Moraes Oliveira, Rio De Janeiro, Brazil

9:00 AM

The Need for Early Diagnostics in a Cardiac Arrest

Vinay M Nadkarni, Philadelphia, PA

9:10 AM

Q&A

9:15 AM

Hands Only CPR, Only?

Karl B Kern, Tucson, AZ

9:25 AM

Q&A

9:30 AM

Adrenaline, To Use or Not To Use

Vinay M Nadkarni, Philadelphia, PA

9:40 AM

Q&A

9:45 AM

Therapeutic Hypothermia for Cardiac Arrest: Yes, We Can

Sergio Timerman, Sao Paulo, Brazil

9:55 AM

Q&A

# Main Event

## AC.ME.596 - ACS Management in 2019 and Beyond

#### Main Event II

### Saturday, November 16, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

James De Lemos, Dallas, TX

9:00 AM

Moderator

Michelle L Odonoghue, Boston, MA

9:00 AM

Moderator

Valentin Fuster, New York, NY

9:00 AM

Case Presentation

9:05 AM

New Insights into Plaque Vulnerability

Renu Virmani, Gaithersburg, MD

9:17 AM

Incorporating High-Sensitivity Troponin into Clinical Practice

David A Morrow, Boston, MA

9:29 AM

Updates in Anti-Thrombotic Therapies

Tracy Wang, Durham, NC

9:41 AM

New Frontiers in Revascularization for ACS

Hani Jneid, Houston, TX

10:05 AM

Case Discussion

# Simulation

## SIM.01 - Case Studies in Ultrasound Simulation

#### Simulation Zone - Heart Hub, Hall C

### Saturday, November 16, 2019, 9:00 AM - 10:00 AM

9:00 AM

Invited Presenter

Ali E Denktas, Houston, TX

# Featured Science

## FS.MDP.01 - A Deeper Dive into Newer Therapies for Heart Failure I

#### Moderated Posters 3, Science and Technology Hall

### Saturday, November 16, 2019, 10:00 AM - 10:50 AM

10:00 AM

Prior Heart Failure Hospitalization, Clinical Outcomes, and Effect of Sacubitril/Valsartan Compared With Valsartan in Heart Failure With Preserved Ejection Fraction

**Muthiah Vaduganathan** , Brigham and Women's Hosp, Cambridge, MA; Brian Claggett, Brigham and Women's Hosp, Boston, MA; Stefan D Anker, Charité Univ Med Berlin, Berlin; Sergio Victor Perrone Sr., Insto Fleni, Buenos Aires, Argentina; Stefan Pierre Janssens, Univ Hosp Gasthuisberg, Leuven, Belgium; Davor Milicic, Universiy Cardiovascular Clinic, Zagreb; Juan Luis Arango, Novartis Pharma Logistics Inc, Guatemala, Mexico; Milton Packer, Baylor Heart and Vascular Inst, Dallas, TX; John J McMurray, BHF Cardiovascular Res Ctr, Glasgow, United Kingdom; Scott Solomon, Brigham and Women's Hosp, Boston, MA

10:10 AM

Impact of Sacubitril/Valsartan on Health-Related Quality of Life in Heart Failure-Preserved Ejection Fraction Patients

**Eldrin F Lewis** , Brigham Women's Hosp, Boston, MA; Gerard C Linssen, Hosp Group Twente, Almelo, United Kingdom; Ben Gal Tuvia, Rabin Medical Ctr (Beilinson Campus), Tel Aviv, Israel; Dragos Vinereanu, Univ Carol Davila, Bucharest; Nancy K Sweitzer, Univ of Arizona, Tucson, AZ; Yoshihiko Saito, Nara Medical Univ, Kashihara, Japan; Adel R Rizkala, Novartis Pharmaceuticals Corp, East Hanover, NJ; Scott D Solomon, Brigham and Women's Hosp, Boston, MA; John J McMurray, BHF Cardiovascular Res Ctr, Glasgow, United Kingdom; Faiez Zannad, INSERM-CIC, Vandoeuvre Les Nancy, France

10:20 AM

Improvement of Health Status Following Initiation of Sacubitril/Valsartan in Patients With Heart Failure and Reduced Ejection Fraction

**Ileana L Pina** , Detroit Medical Ctr Heart Hosp, Cleveland Hghts, OH; Alexander Camacho, Nasrien Ibrahim, Massachusetts General Hosp, Boston, MA; Michael Felker, Duke, Durham, NC; Javed Butler, Univ of Mississippi, Jackson, MS; Alan Maisel, Univ of California, San Diego, CA; Margaret F Prescott, Novartis Pharmaceuticals, Stillwater, MN; Kristin Williamson, Novartis, New York City, NY; Scott Solomon, Brigham and Women's Hosp, Boston, MA; James L Januzzi Jr., Massachusetts General Hosp, Wellesley Hills, MA

10:30 AM

Amino-Terminal Pro-B Type Natriuretic Peptide in the Canagliflozin Cardiovascular Assessment Study (CANVAS) Program

**James L. Januzzi** , Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Jialin Xu, Wayne Shaw, Richard Oh, Girish Ranadive, Janssen Res & Development, LLC, Raritan, NJ; Javed Butler, Stony Brook Heart Inst, Stony Brook, NY; Naveed Sattar, BHF Glasgow Cardiovascular Res Ctr, Univ of Glasgow, Glasgow, United Kingdom; Kenneth Mahaffey, Stanford Ctr for Clinical Res, Dept of Med, Stanford Univ Sch of Med, Stanford, CA; Bruce Neal, Imperial Coll London, UK; The George Inst for Global Health; The Charles Perkins Ctr, Univ of Sydney, NSW Sydney, Australia; Michael K. Hansen, Janssen Res & Development, LLC, Raritan, NJ

10:40 AM

Empagliflozin in Heart Failure: Diuretic and Cardio-Renal Effects

**Matthew Griffin** , Veena Rao, Yale Sch of Med, New Haven, CT; Juan Ivey-Miranda, Insto Mexicano del Seguro Socia, Mexico City, Mexico; James Fleming, Yale Univ Sch of Med, New Haven, CT; Christopher Maulion, Joshua Moskow, Yale, New Haven, CT; Devin Mahoney, Yale Univ, New Haven, CT; Sangchoon Jeon, Yale Sch of Nursing, Orange, CT; Silvio E Inzucchi, Jeffrey M Testani, Yale, New Haven, CT

# Featured Science

## FS.MDP.02 - Observational Studies I

#### Moderated Posters 6, Science and Technology Hall

### Saturday, November 16, 2019, 10:00 AM - 10:50 AM

10:00 AM

Moderator

Sadiya S Khan, Chicago, IL

10:00 AM

Treatment Uptitration Patterns in Patients With Heart Failure With Reduced Ejection Fraction: Data From International Qualify Survey

Martin Cowie, Natl Heart and Lung Inst, Imperial Coll London, London, United Kingdom; Jakob Schöpe, Stefan Wagenpfeil, Inst for Medical Biometry, Homburg, Germany; Luigi Tavazzi, Maria Cecilia Hosp, Cotignola, Italy; **Michael Böhm** , Internal Med Clinic III, Homburg, Germany; Piotr Ponikowski, Dept of Heart Diseases, Wroclaw, Poland; Stefan D Anker, Div of Cardiology and Metabolism, Dept of Cardiology (CVK); and Berlin-Brandenburg Ctr for Regenerative Therapies (BCRT), Berlin, Germany; Gerasimos Filippatos, Dept of Cardiology, Natl and Kapodistrian Univ of Athens, Athens, Greece; Michel Komajda, Dept of Cardiology, Paris, France

10:15 AM

CSI-Kerala Acute Heart Failure Registry (CSI-KAHFR) Data: Less Than 30% of Acute Heart Failure Patients Receive Guideline-Directed Medical Therapy (GDMT)

**Stigi Joseph** , Little Flower Hosp and Res, Kochi, India; Panniyammakal Jeemon, Sree Chitra Tirunal Inst of Science and Technology, Thiruvananthapuram, India; Jabir A, Lisie Hosp, Kochi, India; Harikrishnan S, Sree Chitra Tirunal Inst of Science and Technology, Thiruvananthapuram, India

10:30 AM

Brain-Type Natriuretic Peptides Are Better Markers for Atrial Fibrillation Than for Heart Failure

Stefanie M Werhahn, Christian Becker, Univ Med Göttingen, Goettingen, Germany; Meinhard Mende, Univ Leipzig, Leipzig, Germany; Helge Haarmann, Kathleen Nolte, Univ Med Göttingen, Goettingen, Germany; Ulrich Laufs, Univsklinikum Leipzig, Leipzig; Samira Zeynalova, IMISE, Universtity Leipzig, Leipzig; Markus Löffler, Univ Leipzig, Leipzig, Germany; Nikolaos Dagres, Heart Ctr Leipzig, Leipzig; Daniela Husser, Heart Ctr, Univ of Leipzig, Leipzig; Marcus Dörr, Ernst-Moritz-Arndt Univ, Greifswald, Germany; Stefan Gross, Univ Med Greifswald, Greifswald; Stephan Burkhard Felix, Ernst-Moritz-Arndt, Greifswald, Germany; Astrid Petersmann, Ernst-Moritz-Arndt-Univ Greifswald, Greifswald, Germany; Christoph Herrmann-Lingen, Lutz Binder, Univ Med Göttingen, Goettingen, Germany; Martin Scherer, Univ Hosp Hamburg, Hamburg, Germany; Gerd P Hasenfuss, Georg, Gottingen, Germany; Burkert Pieske, Charite Univ Med Berlin, Berlin, Austria; Frank Edelmann, Charité Univ Med Berlin, Berlin, Germany; **Rolf Wachter** , Univ Hosp Leipzig, Leipzig, Germany

# FIT Event

## FIT.03 - Partnering with Tech in Clinical Care, Research, and Beyond

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Saturday, November 16, 2019, 10:00 AM - 10:45 AM

10:00 AM

Panel Discussion with Jared Magnani, MD, Jeff Hsu, MD PhD, Nosheen Reza, MD and Anum Saeed MD

This is not a CME/CE certified session

# Simulation

## Sim.02 - EP Basic Skills and AF Ablation: Endovascular Procedural Skills

#### Simulation Zone - Heart Hub, Hall C

### Saturday, November 16, 2019, 10:00 AM - 11:00 AM

10:00 AM

Invited Presenter

Jose A Joglar Sr., Dallas, TX

# Abstract Oral Session

## HF.AOS.497 - Laennec Clinician-Educator Award & Lecture/ Laennec Fellows in Training (FIT) Clinician Award Competition

#### 109AB

### Saturday, November 16, 2019, 10:30 AM - 12:15 PM

10:30 AM

Moderator

Doreen DeFaria Yeh, Boston, MA

10:30 AM

Moderator

Eldrin F Lewis, Boston, MA

10:30 AM

Moderator

George Dangas, New York, NY

10:30 AM

Laennec Clinician-Educator Award & Lecture

Emelia J Benjamin, Brookline, MA

10:55 AM

Q & A

11:00 AM

A Twist of Fate: A Case of Cardiac Arrest

**Neel M Butala** , Jacqueline Henson, MGH, Boston, MA; Christopher Newton-Cheh, Massachusetts General Hosp, Lexington, MA

11:10 AM

Q&A

11:15 AM

Pressures at an All-Time High

**Teresa Wang** , Univ of California, San Francisco, San Francisco, CA; Nalini A Colaco, UCSF Div of Cardiology, San Francisco, CA; Sanjeeb Bhattacharya, Teresa De Marco, Univ of California, San Francisco, San Francisco, CA

11:25 AM

Q&A

11:30 AM

Trouble Letting Go (Without a Diagnosis)

**Michael Parker Ayers** , Alexander Gill, Sriram Rao, Michelle Hershman, Donna Kurowski George, Matthew Craig Hyman, Joyce Wald, Hosp of the Univ of Pennsylvania, Philadelphia, PA

11:40 AM

Q&A

11:45 AM

An Unusual, Reversible Cause of Acute High-Output Heart Failure Complicated by Refractory Shock

**Matthew S Durstenfeld** , Univ of California, San Francisco, San Francisco, CA; Alexander Papolos, Luis Rubio, Jonah Garry, UCSF, San Francisco, CA; Michael S Lipnick, Univ of California, San Francisco, San Francisco, CA; Priscilla Y Hsue, Univ of California, San Francisco, CA

11:55 AM

Q&A

12:00 PM

The Double-Edged Sword: A Rare Cause of Arrhythmogenicity in a Breast Cancer Survivor

**Priya P. Mehta** , Jayson R. Baman, Barbara Pro, Lubna Choudhury, Nausheen Akhter, Daniel R Schimmel, Benjamin H. Freed, Sadiya S. Khan, Northwestern Univ, Chicago, IL

12:10 PM

Q & A

# Abstract Oral Session

## AC.AOS.490 - ACS & Interventional Oral Abstracts

#### 103A

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Tracy Y Wang, Durham, NC

10:45 AM

Moderator

Elliott M Antman, Weston, MA

10:45 AM

Treatment Combinations for Elderly Patients and Those With Comorbidities After an Acute Myocardial Infarction

**Linnea Ann Polgreen** , Nick Street, Sulyun Lee, Univ of Iowa, Iowa City, IA

10:55 AM

Q & A

11:00 AM

Outcomes and Effect of PCI Strategies in Culprit-Shock Patients With and Without St-Segment Elevation

**Michel Zeitouni** , Georges Hage, Olivier Barthelemy, Sorbonne Univ, ACTION Study Group, Paris, France; Marie Hauguel, Ambroise Paré Hosp, Boulogne-Billancourt, France; Paul Guedeney, Pitie Salpetriere, Paris; Stephanie Rouanet, Sorbonne Univ, ACTION Study Group, Levallois-Perret, France, France; Pavel Overtchouk, CHU lille, lille, France; delphine brugier, Action-Coeur, PARIS, France; Nicolas Vignolles, Sorbonne Univ, ACTION Study Group, Paris, France; Mathieu Kerneis, Heart Inst, Pitie Salpetriere Hosp, Paris 6 Univ, Paris, France; Johanne Silvain, Pitie-Salpetriere Hosp, PARIS, France; Jean Philippe Collet Jr., Inst de Cardiologie, Paris, France; Eric Vicaut, CHU lariboisiere, PARIS, France; Suzanne de Waha, Heart Ctr Leipzig, Leipzig; Steffen Desch, Univ of Leipzig Heart Ctr, Leipzig; Uwe Zeymer, Klinikum Ludwigshafen, Ludwigshafen; Holger Thiele, Univ Leipzig - Heart Ctr, Leipzig; Gilles Montalescot, Pitie Salpetriere, Paris, France

11:10 AM

Q & A

11:15 AM

Alirocumab and Cardiovascular Outcomes in Older Patients After an Acute Coronary Syndrome: An ODYSSEY OUTCOMES Trial Analysis

Peter R Sinnaeve, Univ Hosp Leuven, Leuven, Belgium; Gregory G Schwartz, Univ of Colorado Sch of Med, Aurora, CO; Daniel Wojdyla, Duke Clinical Res Inst, Durham, NC; Marco Alings, Amphia Ziekenhuis Molengracht, Breda, Netherlands; Vera A Bittner, Univ of Alabama at Birmingham, Birmingham, AL; Deepak L Bhatt, Brigham and Women's Hosp Heart & Vascular Ctr and Harvard Medical Sch, Boston, MA; Chern-En Chiang Sr., Taipei Veterans General Hosp and Natl Yang-Ming Univ, Taipei, Taiwan; Rafael Diaz, Estudios Cardiológicos Latinoamérica, Insto Cardiovascular de Rosario, Rosario, Belgium; Maria Dorobantu, Clinical Emergency Hosp of Bucharest, Bucharest, Romania; Shaun Geoffrey Goodman, St Michael's Hosp, Toronto, ON, Canada; J Wouter Jukema, Leiden Univ Medical Ctr, Leiden, Netherlands; Yong-Un Kim, Sanofi, Paris, France; Robert Pordy, Regeneron Pharmaceuticals, Tarrytown, NY; Michael Szarek, SUNY Downstate SPH, Brooklyn, NY; Harvey D White, Green Lane Cardiovascular Services, Auckland City Hosp, Auckland, New Zealand; Andreas M Zeiher, Goethe Univ, Frankfurt Am Main, Germany; **Philippe Gabriel Steg** , Hôpital Bichat, Paris, France; for the ODYSSEY OUTCOMES Investigators

11:25 AM

Q & A

11:30 AM

Type 2 Myocardial Infarction: Incidence, Risk Factors, and Outcomes Among 41,581 Patients Enrolled in 3 Large Randomized Clinical Trials

**Chiara Melloni** , Duke Clinical Res Inst, Durham, NC; Karen P Alexander, Duke Univ Medical Ctr, Durham, NC; Angie Wu, W. Schuyler Jones, Rajendra H Mehta, Duke Clinical Res Inst, Durham, NC; Robert W Harrison, Duke Univ, Durham, NC; David Kong, Duke Clinical Reseach Inst, Durham, NC; Robin Mathews, Duke Clinical Res Inst, Durham, NC; Thomas J Povsic, Duke Univ Med Ctr, Chapel Hill, NC; Manesh R Patel, Duke Medical Ctr, Durham, NC; Sana M Al-Khatib, Duke Univ Medical Ctr, Durham, NC; Kenneth Mahaffey, Stanford Univ, Stanford, CA; Rury Holman, Univ of Oxford, Oxford, Ukraine; Renato D Lopes, Duke Clinical Res, Durham, NC

11:40 AM

Q & A

11:45 AM

Symptomatic Human Immunodeficiency Virus Infected Patients Receive Less Aggressive Revascularization Management After Acute Coronary Syndrome, a 5-year Nationwide Analysis

**Claire Huang Lucas** , Mount Sinai St Luke's-West Hosp, NYC, NY; Lingling Wu, Mount Sinai St Luke's-West Hosp, New York, NY; Bing Yue, Mount Sinai St. Luke's-West Hosp, New York, NY; Nikhil Bachoo, Mount Sinai St. Luke's-West, New York, NY; Robert Abed, Joshua Berookhim, Xin Wei, Eyal Herzog, Mount Sinai St Luke's-West Hosp, New York, NY

11:55 AM

Q & A

# Abstract Oral Session

## IM.AOS.512 - Charles T. Dotter Memorial Lecture

#### 108B

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Sanjay Misra, Rochester, MN

10:45 AM

Charles T. Dotter Memorial Lecture

Ziv J Haskal, Charlottesville, VA

11:10 AM

Q & A

11:15 AM

Early Detection of Aneurysm of the Ascending Aorta

**Ann Morgenstern** , Dominic Lattanzio, Brandon Mikolich, Jordan Long, Sharon Regional Medical Ctr, Sharon, PA; J Ronald Mikolich, Northeast Ohio Medical Univ, Youngstown, OH

11:25 AM

Q & A

11:30 AM

Early Detection of Aortic Wall Injury in a Mouse Model of Sporadic Aortic Aneurysm and Dissection Using Nanoparticle Contrast-enhanced Computed Tomography

**Ketan Ghaghada** , Baylor Coll of Med/Texas Children's Hosp, Houston, TX; Pingping Ren, Baylor Coll of Med, Houston, TX; Laxman Devkota, Baylor Coll of Med/Texas Children's Hosp, Houston, TX; Zbigniew Starosolski, Texas Children's Hosp, Houston, TX; Igor Stupin, Ananth Annapragada, Baylor Coll of Med/Texas Children's Hosp, Houston, TX; Ying H Shen, Scott A Lemaire, Baylor Coll Med, Houston, TX

11:40 AM

Q&A

11:45 AM

Machine Learning Detection of Endoleak Following Endovascular Aortic Repair

**Mohammad Madani** , Stanford Univ Sch of Med, Stanford, CA; Ali Madani, Ashley Chien, Derek Feriancek, Univ of California, Berkeley, Berkeley, CA; Marta Flory, Hersh Sagreiya, Stanford Univ Sch of Med, Stanford, CA; Mohammad R Mofrad, Univ of California Berkeley, Berkeley, CA; Frandics Chan, Stanford Univ Sch of Med, Stanford, CA

11:55 AM

Q & A

# Abstract Oral Session

## SA.AOS.583 - CVSA Resident Prize

#### 120A

### Saturday, November 16, 2019, 10:45 AM - 11:30 AM

10:45 AM

Moderator

Muralidhar Padala, Atlanta, GA

10:45 AM

Moderator

Jessica Y Rove, Denver, CO

10:45 AM

Hemodynamic Predictors of Right Heart Failure Requiring Right Ventricular Assist Devices After Continuous-flow Left Ventricular Assist Devices Placement

**Dae Hyun Lee** , Zachary Stachura, Deepika Kulkarni, Univ of South Florida, Tampa, FL; Jason Paul Feliberti, Tampa General Medical Group, Tampa, FL; Ricardo Restrepo-Jaramillo, Univ of South Florida, Tampa, FL

10:55 AM

Q & A

11:00 AM

Does Donor Left Ventricular Mass to Recipient Size Affect Heart Transplantation Outcomes? A Single-Center Study Using a Fifty-Year Registry

**Yuanjia Zhu** , Yasuhiro Shudo, Bharathi Lingala, Hao He, Philip E Oyer, Y. Joseph Woo, Stanford Univ, Stanford, CA

11:10 AM

Q & A

11:15 AM

Transcriptomics Reveal Cardioprotective Features of Arteriovenous Fistula-Induced Cardiac Hypertrophy

**Shin-Rong Lee** , Stephanie Thorn, Nicole Guerrera, Yale Univ, New Haven, CT; Albert J Sinusas, Yale Univ Sch Med, New Haven, CT; Alan Dardik, Yale Univ Sch of Med, New Haven, CT

11:25 AM

Q & A

# Abstract Oral Session

## EP.AOS.521 - Elizabeth Barrett-Connor Research Award for Early Career Investigators in Training Competition

#### 201C

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Mahasin S Mujahid, Berkeley, CA

10:45 AM

Incorporation of Biomarkers into Risk Assessment for Allocation of Antihypertensive Medication According to the 2017 Acc/aha High Blood Pressure Guideline: A Pooled Cohort Analysis

**Ambarish Pandey** , Univ of Texas Southwestern Medical Ctr, Dallas, TX; Kershaw Patel, UT Southwestern, Coppell, TX; Wanpen Vongpatanasin, Univ TX Southwestern Med, Dallas, TX; Colby Ayers, UT Southwestern Medical Ctr, Dallas, TX; Jarett D Berry, UT Southwestern Medical Sch, Dallas, TX; Robert John Mentz, Duke Clinical Res Inst, Hillsborough, NC; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; Paul Muntner, Univ Alabama Birmingham, Birmingham, AL; Muthiah Vaduganathan, Brigham and Women's Hosp, Cambridge, MA; Adolfo Correa, U of Mississippi Medical Ctr, Jackson, MS; Javed Butler, Emory, Atlanta, GA; Daichi Shimbo, Columbia Univ, New York, NY; Vijay Nambi, Veterans Affair Hosp, Sugar Land, TX; John W McEvoy, Johns Hopkins Univ Sch of Med, Baltimore, MD; Christopher Defilippi, Inova, Falls Church, VA; Stephen L Seliger, Univ of Maryland Sch of Med, Baltimore, MD; Christie M Ballantyne, Baylor Coll Med, Houston, TX; James A De Lemos, Parag H Joshi, UT Southwestern Medical Ctr, Dallas, TX

10:55 AM

Q & A

11:00 AM

Changes in Cardiac Structure Over 20 Years Are Associated With Lower Midlife Cognition: The Coronary Artery Risk Development in Young Adults (CARDIA) Study

**Laure Rouch** , UCSF, San Francisco, CA; Feng Xia, Northern California Inst for Res and Education, San Francisco, CA; Steve Sidney, Kaiser Permanente Northern California, Oakland, CA; Joao AC Lima, Johns Hopkins Univ, Baltimore, MD; Kristine Yaffe, UCSF, San Francisco, CA

11:10 AM

Q & A

11:15 AM

Novel Sex- and Race-Specific Models for 30-Year Risk Estimation of Incident Heart Failure

**Sadiya S. Khan** , Northwestern Univ, Oak Park, IL; Hongyan Ning, Norrina B Allen, Mercedes R Carnethon, Clyde W Yancy Jr., John T Wilkins, Donald M Lloyd-Jones, Northwestern Univ, Chicago, IL

11:25 AM

Q & A

11:30 AM

Trends in Lipid, Lipoproteins and Statin Use Among US Adults: Impact of the 2013 AHA/ACC Cholesterol Guidelines

**Nirav Patel** , Univ of Alabama at Birmingham, Birmingham, AL; Anirudh Bhargava, UAB Internal Med, Birmingham, AL; Vibhu Parcha, Univ of Alabama, Birmingham, AL; Rajat Kalra, Univ of Alabama, Birmingham, AL, Minneapolis, MN; Garima Arora, Univ of Alabama at Birmingham, Birmingham, AL; Paul Muntner, Univ Alabama Birmingham, Birmingham, AL; Pankaj Arora, Univ of Alabama at Birmingham, Birmingham, AL

11:40 AM

Q & A

11:45 AM

Long-term Cumulative Blood Pressure in Young Adults and Incident Heart Failure, Coronary Events, Stroke, Cardiovascular Disease, and Mortality: The Coronary Artery Risk Development in Young Adults (CARDIA) Study

**Chike C Nwabuo** , Johns Hopkins Univ, Baltimore, MD; Duke Appiah, Texas Tech Univ HSC, Lubbock, TX; Henrique T Moreira, Henrique D Vasconcellos, Johns Hopkins Univ, Baltimore, MD; Yuichiro Yano, Duke Univ, Durham, NC; Paul Muntner, Univ Alabama Birmingham, Birmingham, AL; Jared P Reis, Natl Heart Lung Blood Inst, Bethesda, MD; Ravi V Shah, Harvard Medical Sch, Newburyport, MA; Venkatesh L Murthy, Univ of Michigan, Ann Arbor, MI; Norrina B Allen, Northwestern Univ, Chicago, IL; Stephen Sidney, Kaiser Permanente Medical Care, Oakland, CA; Cora E Lewis, Univ Alabama Birmingham, Birmingham, AL; Donald M Lloyd-Jones, Northwestern Univ, Chicago, IL; Pamela Schreiner, Univ Minnesota, Minneapolis, MN; Samuel Gidding, FH Fndn, Pasadena, CA; Joao A Lima, Johns Hopkins Univ, Baltimore, MD

11:55 AM

Q & A

# Abstract Oral Session

## ST.AOS.502 - Stroke Council Award & Lecture

#### 118A

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Peter D Panagos, St Louis, MO

10:45 AM

Stroke Council Award & Lecture

Louise D Mccullough, Houston, TX

11:10 AM

Q&A

11:15 AM

The Difference in Microembolic Signals Rate During Carotid Endarterectomy and Carotid Artery Stenting

Jose M. Wiley, Montefiore Medical Ctr, Albert Eistein Coll of Med, Bronx, NY; **Cristina Sanina** , Montefiore Albert Eist Colle of Med, Bronx, NY; Guliz Kozdag, Montefiore Medical Ctr, Bronx, NY

11:25 AM

Q & A

11:30 AM

The Cost Effectiveness of Mobile Stroke Unit Compared to the Standard Care Ambulance in the United States

**Salin Sriudomporn** , Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Ryan R Nugraha, Ctr for Health Economics and Policy Studies, Depok, Indonesia; Nishtha Ahuja, Emmanuel Drabo, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD

11:40 AM

Q & A

11:45 AM

Brain Natriuretic Peptide Predicts Long-term Outcome for Non-traumatic Subarachnoid Hemorrhage

**Takanao Mine** , Hyogo Coll of Med, Nishinomiya, Japan; Tomotaka Ando, Nishinomiya Kyoritsu Neurosurgical Hosp, Nishinomiya, Japan; Hideyuki Kishima, Eiji Fukuhara, Masaharu Ishihara, Hyogo Coll of Med, Nishinomiya, Japan

11:55 AM

Q & A

# Abstract Oral Session

## NR.AOS.368 - The Game of Life: Society and CVD Risk

#### 118C

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Lucinda J Graven, Tallahassee, FL

10:45 AM

Moderator

Andrea Driscoll, Viewbank, Australia

10:45 AM

Cardiovascular Stroke Nursing Best Abstract Award: **Can Adverse Social Determinants of Health be Overcome by Cardiovascular Risk Reduction Interventions Designed Specifically for Rural Socioeconomically Distressed Environments?**

**Debra K Moser** , Misook L Chung, Jennifer L Miller, Gia Mudd-Martin, Mary Kay Rayens, Terry A Lennie, Univ of Kentucky, Lexington, KY

10:55 AM

Q & A

11:00 AM

Profile of Informal Rural Caregivers of Patients With Chronic Illnesses: At High Risk for Cardiovascular Disease

**Jennifer L. Smith** , Univ of Kentucky, Lexington, KY; Misook Lee Lee Chung, Univ of Kentucky Coll of Nur, Lexington, KY; Jennifer Miller, Univ of Kentucky, Frankfort, KY; Debra K Moser, Univ of Kentucky, Lexington, KY

11:10 AM

Q & A

11:15 AM

Racial Inequities in Hypertension Diagnosis: Non-Whites More Likely to Have Undiagnosed Hypertension

**Kelly Gleason** , Katharine Henry, Johns Hopkins Univ, Baltimore, MD; Martha Abshire, Johns Hopkins Univ Sch of Nursing, Baltimore, MD; Cheryl Dennison Himmelfarb, Johns Hopkins Univ, Baltimore, MD

11:25 AM

Q & A

11:30 AM

Sociodemographic and Clinical Determinants of Self-Care and Caregiver Contribution to Self-Care in a Context of Multiple Chronic Conditions

**Paolo Iovino** , Univ of Tor Vergata, Rome, Italy; Maria Matarese, Campus Biomedico Roma, Rome, Italy; Ercole Vellone, Univ of Rome Tor Vergata, Rome, Italy; Davide Ausili, Univ of Bicocca, Milan, Italy; Maddalena De Maria, Univ of Tor Vergata, Rome, Italy; Karen Lyons, Boston Coll, Chestnut Hill, MA; Christopher Lee, Boston Coll Massachusetts, Boston, MA; Silvia Lorini, Univ of Tor Vergata, Rome, Italy; Barbara J Riegel, Univ Pennsylvania, Philadelphia, PA

11:40 AM

Q & A

11:55 AM

Q & A

# Cardiovascular Seminar

## CH.CVS.416 - Advances in Fontan Management

#### 112AB

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Valeria Duarte, Dedham, MA

10:45 AM

Moderator

Jennifer L Conway, Edmonton, AB, Canada

10:45 AM

Improving the Detection of End-Organ Dysfunction in the Fontan Patient

Ari M Cedars, Dallas, TX

11:00 AM

The Role of Perioperative Vasodilators and Remodeling Agents in Fontan Patients

Rachel K Hopper, Palo Alto, CA

11:15 AM

The Assessment of Cardiopulmonary Well-Being in the Fontan Patient

Elisa A Bradley, Columbus, OH

11:30 AM

Results of the PHN Multi-Center FUEL Study

David J Goldberg, Philadelphia, PA

11:45 AM

Mechanical Circulatory Support in the Fontan Patient

Angela Lorts, Cincinnati, OH

# Cardiovascular Seminar

## EA.CVS.220 - Atrial Fibrillation: How to Manage Complex Clinical Scenarios

#### 113BC

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Zhengou Liu, Columbia, MO

10:45 AM

Moderator

Mintu Turakhia, Palo Alto, CA

10:45 AM

Does Asymptomatic AF Truly Exist?

Wendy S Tzou, Aurora, CO

10:57 AM

Q & A

11:00 AM

Non-paroxysmal Atrial Fibrillation Ablation: Going Beyond Pulmonary Vein Isolation

Michael Field, Charleston, SC

11:12 AM

Q & A

11:15 AM

How Do We Address the LA Appendage? Isolate, Occlude or Both?

Mark Estes III, Boston, MA

11:27 AM

Q & A

11:30 AM

Persistent Left Atrial Appendage Thrombus - Management Strategies

Boris Schmidt, Frankfurt, Germany

11:42 AM

Q & A

11:45 AM

Oral Anticoagulation Following AF Ablation +/- LAA Occlusion

claudio Tondo, Milan, Italy

11:57 AM

Q & A

# Cardiovascular Seminar

## LF.CVS.383 - Cardiometabolic Health, Fitness and HFpEF: Novel Insights and Approaches

#### 201AB

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Todd M Brown, Birmingham, AL

10:45 AM

Moderator

Marie-Eve Piche, Quebec, QC, Canada

10:45 AM

Cardiometabolic Mechanisms of HFpEF: From Bench to Bedside

Michael R Zile, Charleston, SC

11:00 AM

Using Cardiac Metabolism to Understand Disease and Evaluate Interventions in HFpEF

Kim A Connelly, Toronto, ON, Canada

11:15 AM

What 'Dose' and 'Type' of Exercise is Right for My Patient With HFpEF?

Martin Halle, Munich

11:30 AM

The Intersection of Fitness, Fatness and HFpEF

Ambarish Pandey, Dallas, TX

11:45 AM

Can We Use Cardiometabolic Interventions to Successfully Treat HFpEF?

Oliver Rider, oxford, United Kingdom

# Cardiovascular Seminar

## CM.CVS.438 - Diabetes and Multi-Organ Disease: CKD, ASCVD, HF, PAM

#### 204AB

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Mercedes Carnethon, Chicago, IL

10:45 AM

Moderator

Anand Rohatgi, Dallas, TX

10:45 AM

Diabetes and Chronic Kidney Disease: Pathophysiology and Presentation

Vito M Campese, Los Angeles, CA

11:00 AM

Diabetes and ASCVD: How and How Much?

Peter Wilson, Atlanta, GA

11:15 AM

Diabetes and Peripheral Arterial Disease

Mary M McDermott, Chicago, IL

11:30 AM

How to Prevent Multiorgan Dysfunction in Diabetes?

Neha Pagidipati, Durham, NC

11:45 AM

Diabetes and Clinical Manifestations of Heart Failure

Eldrin F Lewis, Boston, MA

# Cardiovascular Seminar

## CH.CVS.35 - FH in Children - What Children / Families Want From Providers?

#### 111AB

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Michele Mietus-Snyder, Washington, DC

10:45 AM

Moderator

Geetha Raghuveer, Kansas City, MO

10:45 AM

Patient / Family Case Presentation

Cat Davis Ahmed, Pasadena, CA

11:00 AM

Optimizing Screening of Families in FH: Interpreting the Guidelines

Sarah Deferranti, Boston, MA

11:15 AM

It is Not All About LDL - Other Risks

Michael Khoury, Cincinnati, OH

11:30 AM

Evidence Suggests We Should Begin Statins Early

Elaine URBINA, Cincinnati, OH

11:45 AM

Life-long Management of FH

Annette Baker, Boston, MA

# Cardiovascular Seminar

## QU.CVS.384 - Great Debates in Quality and Outcomes

#### 202AB

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Rashmee U Shah, Salt Lake City, UT

10:45 AM

Moderator

Prateeti Khazanie, Aurora, CO

10:45 AM

Professional Societies Should Abstain From Authorship of Guidelines and Disease Definition Statements

Rita F Redberg, San Francisco, CA

10:54 AM

Expert Advice Comes From Experts: Guidelines Need to Be Written by Professional Societies

Eric D Peterson, Chapel Hill, NC

11:12 AM

Keep Your Government Hands off My MediCare: Private Health Insurance is Needed

Karen Joynt Maddox, Saint Louis, MO

11:21 AM

The Electronic Health Record Will Ultimately Save Us

Jason H Wasfy, Boston, MA

11:30 AM

The Electronic Health Record Will Ruin HealthCare

Vinay Kini, Aurora, CO

11:39 AM

We Should Use Real-World Evidence to Guide Clinical and Regulatory Decisions

David Holmes, Rochester, MN

11:48 AM

We Should NOT Use Real-World Evidence to Guide Clinical and Regulatory Decisions

Christopher B Granger, Durham, NC

10:45 AM

Panel Participant

Prateeti Khazanie, Aurora, CO

10:45 AM

Panel Participant

Rashmee U Shah, Salt Lake City, UT

# Cardiovascular Seminar

## HY.CVS.128 - Hypertension Issues In Women

#### 105AB

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Phyllis A August, New York, NY

10:45 AM

Moderator

Suzanne Oparil, Birmingham, AL

10:45 AM

Overview of HTN Across a Woman's Lifecycle

Nanette Wenger, Atlanta, GA

10:58 AM

HTN in Pregnancy

Natalie A Bello, New York, NY

11:10 AM

Gender Differences in HTN Therapies/Inclusion of Women in Clinical Trials of HTN Medications and Therapies

Tara I Chang, Palo Alto, CA

11:22 AM

HTN Resulting From Chemotherapy/CVD Implications of Breast Cancer Treatment

Rhian Touyz, Glasgow, United Kingdom

11:35 AM

Fibromuscular Dysplasia

Jeffrey W Olin, New York, NY

11:48 AM

May Measurement Month, MMM17 & MMM18, the Woman Hypertension Prevalence Around the World

Aletta E Schutte, Potchefstroom

# Cardiovascular Seminar

## IN.CVS.442 - PFO Closure and Cryptogenic Stroke - Emerging Evidence, Indications, and Techniques

#### 107AB

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

John Carroll, Aurora, CO

10:45 AM

Moderator

KELLY EPPS, Washington, DC

10:45 AM

Case Presentation

Satya Shreenivas, Philadelphia, PA

10:50 AM

The Work-up of Cryptogenic Stroke: What Algorithm Should I Use?

Steven MESSE, Philadelphia, PA

11:00 AM

To Close or Not to Close the PFO: How Current Evidence Has Transformed the Foundation of PFO Management

Jeffrey L Saver, Los Angeles, CA

11:10 AM

The Role of Imaging in Patient Selection and Procedural Planning

Rebecca T Hahn, New York, NY

11:20 AM

The Current Landscape of Devices for PFO Closure

Horst Sievert, Frankfurt

11:30 AM

Discussion

# Cardiovascular Seminar

## HY.CVS.397 - Populations without Compelling Evidence to Guide Treatment

#### 108A

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

John D Bisognano, Rochester, NY

10:45 AM

Moderator

Shawna Nesbitt, Dallas, TX

10:45 AM

How Aggressively to Treat Nonagenarians With Hypertension

Kevin McCormick, Rochester, NY

11:05 AM

Hypertension in Twenty-somethings: How Aggressively to Treat?

Marc Lande, NY

11:25 AM

What to Do With the Patient Who has Trouble With Every Medication They Try: Panel Case Discussion With Audience Participation

Joseph Izzo, Buffalo, NY

11:45 AM

Discussant

Angela L Brown, Saint Louis, MO

# Cardiovascular Seminar

## PH.CVS.482 - State-of-the-Art Management and Endpoints in Pulmonary Arterial Hypertension

#### 102AB

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Anjali Vaidya, Philadelphia, PA

10:45 AM

Moderator

Elizabeth Gay, Boston, MA

10:45 AM

An Updated Management Algorithm for PAH: the US Experience

Roham T Zamanian, Stanford, CA

11:00 AM

An Updated Management Algorithm for PAH: the EU Experience

Olivier Sitbon, Le Kremlin Bicetre, France

11:15 AM

Functional Assessments: Exercise Testing, 6MWT, SHAPE, Risk Scores, and Patient Reported Outcomes

Mardi I Gomberg-Maitland, Falls Church, VA

11:30 AM

Latest in Imaging Diagnostics and Follow Up: ECHO, MRI, HRCT, Perfusion Scintigraphy

David Kiely, Sheffield

11:45 AM

Latest Advances in Invasive Diagnostics and Follow Up: Invasive Hemodynamics and CPET

Marc A Simon, Pittsburgh, PA

# Cardiovascular Seminar

## PR.CVS.204 - Taming the Hydra- Rethinking Nicotine Prevention and Treatment

#### 204C

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Nancy Rigotti, Boston, MA

10:45 AM

Moderator

Pamela Morris, Mt Pleasant, SC

10:45 AM

Nicotine Delivery, Pharmacokinetics and Cardiovascular Physiology

Neal L Benowitz, San Francisco, CA

10:57 AM

Nicotine Addiction and Dependence and Youth: Implications for Future Development of Cardiovascular Disease

Suchitra Krishnan-Sarin, New Haven, CT

11:09 AM

Prevalence and Use of E-cigarettes

Michael Blaha, Baltimore, MD

11:21 AM

Cardiovascular Effects of E-cigarettes: Role of Nicotine

Holly Middlekauff, Los Angeles, CA

11:33 AM

New Approaches to Tobacco Cessation

Nancy Rigotti, Boston, MA

# Frontiers in Science

## EA.FIS.601 - Arrhythmia Research Summit: New Arrhythmia Concepts

#### 119AB

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Elaine Y. Wan, New York, NY

10:45 AM

Moderator

Dan M Roden, Nashville, TN

10:45 AM

Metabolic Determinants of Arrhythmogenesis

David Van Wagoner, Cleveland, OH

10:55 AM

Q&A

10:57 AM

WNT Signaling in Cardiac Arrhythmogenesis

Stacey Rentschler, Saint Louis, MO

11:02 AM

Q&A

11:03 AM

Atrial Electrical and Structural Remodeling During Hemodynamic Stress: Role of ETV1 Signaling

David Park, New York, NY

11:08 AM

Q&A

11:09 AM

SK Channels in Electrical Remodeling and Calcium Signaling

Nipavan Chiamvimonvat, Davis, CA

11:14 AM

Q&A

11:15 AM

Intra-Myocardial Fat and Arrhythmias

Saman NAZARIAN, Philadelphia, PA

11:20 AM

Q&A

11:21 AM

Excess Exercise and Risk for AF

John M Mandrola, Louisville, KY

11:26 AM

Q&A

11:27 AM

TMAO, the gut-microbiome and AF risk

Sunny Po, Oklahoma City, OK

11:32 AM

Q&A

11:33 AM

New Insights Into Sodium Channels and Arrhythmogenesis

Isabelle DESCHENES, Cleveland, OH

11:38 AM

Q&A

11:39 AM

Stretch and Cardiac Electrical Remodeling

Andreas Werdich, BOSTON, MA

11:44 AM

Q&A

11:45 AM

Oxidative stress: back in the crosshairs for AF

Rishi Arora, Chicago, IL

11:50 AM

Q&A

11:51 AM

Single Cell Sequencing of the Human Heart

Nathan R Tucker, Boston, MA

11:56 AM

Q&A

# Hall

## EP.HT.08 - Device Troubleshooting

#### EP Central

### Saturday, November 16, 2019, 10:45 AM - 11:30 AM

10:45 AM

Moderator

Anne Kroman, Seattle, WA

10:45 AM

Panel Participant

Ratika Parkash, Halifax, NS, Canada

# Hall

## EA.HT.54 - ECG Jeopardy

#### Game Central

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Zachary Goldberger, Seattle, WA

10:45 AM

Moderator

Miguel Angelo Leal, Madison, WI

10:45 AM

UnKnown ECG #1

Adrian Baranchuk, Kingston, ON, Canada

10:55 AM

UnKnown ECG #2

Lynda E Rosenfeld, Hamden, CT

11:05 AM

UnKnown ECG #3

Nora F Goldschlager, San Francisco, CA

11:15 AM

UnKnown ECG #4

Melvin M SCHEINMAN, San Francisco, CA

11:25 AM

UnKnown ECG #5

Elizabeth Stephenson, Toronto, ON, Canada

11:45 AM

Q&A

# Joint Sessions

## EA.JS.1629 - Arrhythmia Management in 2019: AHA Joint Session with Iranian Heart Association

#### 103C

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Frank W Sellke, Providence, RI

10:45 AM

Moderator

Anita Sadeghpour, Tehran, Iran, Islamic Republic of

10:55 AM

Q&A

10:57 AM

The Rising Prevalence of Metabolic Syndrome and The Investigation of its Underlying Genetics Causes in Iran

Arya Mani, New Haven, CT

11:07 AM

Q&A

11:09 AM

Atrial Fibrillation in Valvular Heart Disease, Role of Echocardiograp

Anita Sadeghpour, Tehran, Iran, Islamic Republic of

11:19 AM

Q&A

11:22 AM

Post-Operative Atrial Fibrillation

Frank W Sellke, Providence, RI

11:32 AM

Q&A

11:44 AM

Q&A

11:56 AM

Q&A

# Joint Sessions

## CS.JS.611 - European Heart Journal Session

#### 126A

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Thomas F Luescher, Zurich, Switzerland

10:45 AM

Moderator

Noel Bairey-Merz, Los Angeles, CA

10:45 AM

Prevention: New Evidence and Perspectives

Christopher Paul Cannon, Boston, MA

11:00 AM

Imaging: How to Use the Different Modalities

Jeroen J Bax, Leiden, Netherlands

11:15 AM

Coronary Intervention

Roxana Mehran, New York, NY

11:45 AM

Heart Failure from HFrEF to HFpEF

Marc A Pfeffer, Boston, MA

# Joint Sessions

## IM.JS.1644 - Global Roundtable: Artificial Intelligence in Cardiovascular Imaging American Heart Association, European Association of Nuclear Medicine (EANM), Saudi Society of Echocardiography (SASE) and Argentine Society of Cardiology (SAC)

#### 103B

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

CT-Fractional Flow Reserve Applications Automated Measurements

Diego Perez de Arenaza, Buenos Aires, Argentina

11:00 AM

Artificial Neural Networks in Cardiovascular Imaging

Luis Eduardo Juarez-Orozco, Turku, Finland

11:15 AM

Opportunities and Challenges for Artificial Intelligence in CV Imaging

Menwar Majnoni, Saudi Arabia

11:30 AM

Panel Discussion

# Joint Sessions

## PR.JS.1611 - Global Roundtable: Cardio-Oncology Rehabilitation (CORE) to Manage Cardiovascular Outcomes in Cancer Patients and Survivor(SOCHICAR, The Danish Society of Cardiology and Italian Association of Hospital Cardiologists (ANMCO)

#### 121A

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Kornelia Kotseva, London, United Kingdom

10:45 AM

CV Risk Factor Management in a Cancer Patient

Alejandro Dapelo, Concepcion, Chile

11:05 AM

Long Term Risk of Heart Failure After Epirubicin or Trastuzumab Treatment - Relative Versus Absolute Risk

morten Schou, Copenhagen, Denmark

11:25 AM

Clinical Management of Coronary Artery Disease in Cancer Patients and Survivors

Furio Colivicchi, MILANO, Italy

11:45 AM

Panel Discussion

# Joint Sessions

## CS.JS.1630 - Reducing the Global Burden of Cardiovascular Disease: AHA Joint Session with World Heart Federation

#### 126B

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Mark A Creager, Lebanon, NH

11:00 AM

TBD

Rita R Kalyani, Baltimore, MD

11:15 AM

Global Actions to Reduce the Burden of Cardiovascular Disease

Dorairaj Prabhakaran, Gurgaon, India

11:45 AM

Q&A

# Late-Breaking Science

## LBS.01 - Late Breaking Science I: Outside the Box: New Approaches to CVD Risk Reduction

#### Main Event I

### Saturday, November 16, 2019, 10:45 AM - 12:10 PM

10:45 AM

Moderator

Ivor J Benjamin, Milwaukee, WI

10:45 AM

Moderator

Joseph A Hill, Dallas, TX

10:45 AM

Social Media Moderator

Ann Marie Navar, Durham, NC

10:45 AM

Setting the Stage: SGLT2i for Non-Diabetics?

Larry A Allen, Aurora, CO

10:48 AM

The Dapagliflozin and Prevention of Adverse-Outcomes in Heart Failure Trial (DAPA-HF): Results in Nondiabetic Patients

**John J v McMurray** , BHF Cardiovascular Res Ctr, Glasgow, United Kingdom; David L DeMets, Univ of Wisconsin, Madison, WI; Silvio E Inzucchi, Yale Univ Sch of Med, New Haven, CT; Lars Kober, Rigshospitalet, Copenhagen, Denmark; Mikhail N Kosiborod, St. Luke's Health System, Kansas City, MO; Anna Maria langkilde, AstraZenca, Gothenburg, Sweden; Felipe Martinez, Insto Damic, Cordoba, Argentina; Olof Bengtsson, AstraZenca, Gothenburg, Sweden; Piotr Ponikowski, Medical Univ, Wroclaw, Poland; Marc S Sabatine, TIMI Study Group, Boston, MA; Mikaela Sjostrand, AstraZenca, Gothenburg, Sweden; Scott Solomon, Brigham and Women's Hosp, Boston, MA

10:56 AM

Discussant

Larry A Allen, Aurora, CO

11:03 AM

Setting the Stage: Statins to Ezetimibe to PCSK9i; What's Next?

Karol E Watson, Los Angeles, CA

11:06 AM

Safety and Efficacy of Inclisiran in Patients With ASCVD and Elevated LDL Cholesterol - Results From the Phase 3 ORION-10 Trial

**R. Scott Wright** , Mayo Clinic, Rochester, MN; Kausik K Ray, Imperial Coll London, London, United Kingdom; David Kallend, The Meds Company, Parsippany, NJ; Wolfgang Koenig, Univ of Ulm Medical Ctr, Ulm, Germany; Frederick J Raal, Johannesburg Hosp, Johannesburg, South Africa; Lawrence A. Leiter, Univ of Toronto, Toronto, ON, Canada; Peter L Wijngaard, The Meds Company, Parsippany, NJ; Johannes JP Kastelein Jr., Academic Medical Ctr, Amsterdam, Netherlands

11:14 AM

Discussant

Karol E Watson, Los Angeles, CA

11:21 AM

Setting the Stage: Colchicine for Acute CV Conditions; What's Next?

Aruna D Pradhan, Boston, MA

11:24 AM

The COLchicine Cardiovascular Outcomes Trial (COLCOT)

**Jean-Claude Tardif** , Montreal Heart Inst, Montreal, QC, Canada; Simon Kouz, CHRDL, Joliette, QC, Canada; David D Waters, San Francisco General Hosp, San Francisco, CA; Rafael Diaz, Estudios Clinicos Latinoamerica, Rosario, Argentina; Aldo P Maggioni, ANMCO Res Ctr, Firenze, Italy; Fausto J Pinto, Lisbon Univ Medical Sch, Lisboa, Portugal; Habib Gamra, Univ Hosp, Monastir, Tunisia; Ghassan S Kiwan, Bellevue Univ Medical Ctr, Beirut, Lebanon; Colin Berry, Univ of Glasgow, Glasgow, United Kingdom; Jose Luis Lopez-Sendon, Hosp Univrio La Paz, Madrid, Spain; Reda Ibrahim, Montreal Heart Inst, Montreal, QC, Canada; Wolfgang Koenig, Deutsches Herzzentrum Muenchen, Munich, Germany; Petr Ostadal, Na Homolce Hosp, Prague, Czech Republic; Jean C Gregoire, Montreal Heart Inst, Montreal, QC, Canada; Mylene Provencher, Marieve Cossette, Anna Nozza, Lucie Blondeau, Montreal Health Innovations Coordinating Ctr, Montreal, QC, Canada; Philippe L. L'Allier, Montreal Heart Inst, Montreal, QC, Canada; Marie-Claude Guertin, Montreal Health Innovations Coordinating Ctr, Montreal, QC, Canada; Francois Roubille, Univ of Montpellier, Montpellier, France

11:32 AM

Discussant

Aruna D Pradhan, Boston, MA

11:39 AM

Setting the Stage: Epigenetics and CVD Risk; The Next Target?

Svati H Shah, Hillsborough, NC

11:42 AM

**Effect of** BET **Protein Inhibition With** Apabetalone **on Cardiovascular Outcomes in Patients With Acute Coronary Syndrome and Diabetes - Results of the BETonMACE Trial**

**Kausik K Ray** , Imperial Coll London, London, United Kingdom; Stephen J Nicholls, Monash Univ, Melbourne, Australia; Henry N Ginsberg, Columbia Univ, New York, NY; Jan O Johansson, Resverlogix Corp, Calgary, AB, Canada; Kamyar Kalantar-Zadeh, Univ of California Irvine, Orange, CA; Ewelina Kulikowski, Resverlogix Corp, Calgary, AB, Canada; Peter P. Toth, Univ of Illinois Coll of Med, Peoria, IL; Norman Wong, Michael Sweeney, Resverlogix Corp, Calgary, AB, Canada; Gregory G Schwartz, VA Eastern Colorado Healthcare System, Aurora, CO; BETonMACE Investigators

11:50 AM

Discussant

Svati H Shah, Hillsborough, NC

12:00 PM

Discussion

# Main Event

## IM.ME.509 - Hand in Hand: Healthy Heart, Healthy Brain

#### Main Event II

### Saturday, November 16, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Robert gropler, ST Louis, MO

10:45 AM

Moderator

Geoffrey D. Rubin, Durham, NC

10:45 AM

Association of White Matter Abnormalities and Heart Disease

Paolo G Camici, Milano, Italy

11:00 AM

Emotional Stress and Cardiovascular Disease

Ahmed A Tawakol, Boston, MA

11:15 AM

Linking Stroke and Acute Cardiac Syndromes: Cellular and Molecular Mechanisms

Frank M Bengel, Hannover, Germany

11:30 AM

Panel Discussion and Q&A: Leveraging Interdisciplinary Collaborations for Novel Therapies

Chiara Bucciarelli-ducci, Bristol, United Kingdom

# Main Event

## CS.ME.100 - Science Catalyst Keynote

#### Nutter Theatre

### Saturday, November 16, 2019, 10:45 AM - 11:45 AM

10:45 AM

Science Catalyst Keynote

Eric N Olson, Dallas, TX

# FIT Event

## FIT.14 - Matching into Cardiology Fellowship: The Inside Scoop From Program Directors & AHA FITs

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Saturday, November 16, 2019, 11:00 AM - 11:45 AM

This is not a CME/CE certified session

# Simulation

## SIM.03 - Virtual Patient Challenge

#### Simulation Zone - Heart Hub, Hall C

### Saturday, November 16, 2019, 11:00 AM - 12:00 PM

11:00 AM

Invited Presenter

Connie W Tsao, Boston, MA

# Council Sponsored Activities

## CSA.04 - CLCD Women In Cardiology Networking Luncheon

#### Philadelphia Marriott Downtown Hotel, Franklin 11/12

### Saturday, November 16, 2019, 11:30 AM - 1:30 PM

This is not a CME/CE certified session

# Council Sponsored Activities

## CSA.11 - CVSN Pediatric Nursing Luncheon

#### Philadelphia Marriott Downtown Hotel, Salon A

### Saturday, November 16, 2019, 11:30 AM - 2:00 PM

This is not a CME/CE certified session

# Early Career

## EA.HT.274 - Cardiac Electrophysiology Sessions for AHA Early Career Day - Part 2: How I Got Here: A Panel Discussion on the Different Types of EP Career Options

#### EP Central

### Saturday, November 16, 2019, 11:30 AM - 12:20 PM

11:30 AM

Moderator

Jonathan Dukes, Ventura, CA

11:30 AM

Moderator

Jeanne Poole, Seattle, WA

11:30 AM

Clinical Trials

Douglas L Packer, Rochester, MN

11:40 AM

VA Careers

David Krummen, San Diego, CA

11:50 AM

Epidemiology and Observational Studies – Early Career Prospective

Christine Albert, Boston, MA

12:00 PM

Research Private Practice: How to Make it Work

Thomas Bunch, Murray, UT

12:10 PM

Panel Discussion

# Council Sponsored Activities

## CSA.15 - Young Hearts Early Career Networking Luncheon

#### Philadelphia Marriott Downtown hotel, room Independence Ballroom 1/2/3

### Saturday, November 16, 2019, 12:00 PM - 2:00 PM

This is not a CME/CE certified session

# Expert Theater

## ET.01 - Amgen, Inc.

#### Heart Theater, Booth # 17

### Saturday, November 16, 2019, 12:00 PM - 12:45 PM

This is not a CME/CE certified session

# Expert Theater

## ET.02 - Janssen Pharmaceuticals, Inc

#### Learning Studio 1, Booth # 5

### Saturday, November 16, 2019, 12:00 PM - 12:45 PM

This is not a CME/CE certified session

# Expert Theater

## ET.03 - Sanofi Regeneron

#### Learning Studio 2, Booth # 7

### Saturday, November 16, 2019, 12:00 PM - 12:45 PM

This is not a CME/CE certified session

# Abstract Rapid Fire Oral

## EA.RFO9 - Atrial Fibrillation - Monitoring and Special Risk Groups

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 12:30 PM - 1:20 PM

12:30 PM

Moderator

Marco Mercader, Washington, DC

12:30 PM

Early Experience With Novel Real-Time and Extended Wear Continuous Cardiac Rhythm Monitor

**Mehdi Razavi** , Texas Heart Inst, Houston, TX; Lori Crosson, iRhythm Technologies Inc, Lincolnshire, IL; Mike Hsu, Julie Campioni, iRhythm Technologies Inc, San Francisco, CA; Judith C Lenane, iRhythm Technologies Inc, Lincolnshire, IL

12:35 PM

Q & A

12:40 PM

Development of an Atrial Fibrillation Risk Score in Patients With Diabetes: The Action to Control Cardiovascular Risk in Diabetes (ACCORD) Study

**Ping Yang** , First Affiliated Hosp of Kunming Medical Univ, Kunming, China; Yanglu Zhao, UCLA, Los Angeles, CA; Nathan D Wong, Univ of California Irvine, Irvine, CA

12:45 PM

Q & A

12:50 PM

Mortality in Patients With Marfan and Atrial Fibrillation

**Apas Aggarwal** , Divyang Patel, Anirudh Kumar, Kevin Chen, Erika Hutt, Lars Svensson, Eric E Roselli, Mohammed Kanj, Ayman Hussein, Oussama Musbah Wazni, Cleveland Clinic Fndn, Cleveland, OH; Milind Desai, Cleveland Clinic Fndn, Solon, OH; Vidyasagar Kalahasti, Cleveland Clinic Fndn, Cleveland, OH

12:55 PM

Q & A

1:00 PM

A Real-world Experience For Implantable Loop Recorder Monitoring To Detect Subclinical Atrial Fibrillation In Patients With Cryptogenic Stroke

**Daniel Marks** , Cooper Univ, Camden, NJ; Rady Ho, Cooper Univ Hosp, Camden, NJ; Karim Nathan, Cooper Univ Hosp, Philadelphia, PA; Joshua Weinstock, Cooper Univ Hosp, Cherry Hill, NJ; Krystal Hunter, Cooper Hosp, Camden, NJ; Matthew Ortman, Cooper Univ Hosp, Camden, NJ; Andrea M Russo, Cooper Univ Hosp, Moorestown, NJ

1:05 PM

Q & A

1:10 PM

Atrial Fibrillation and Mortality in Patients With LVAD: A Single Center Cohort

**Baris Akdemir** , Zeina Jedeon, Rebecca Cogswell, Jessica Schultz, Lisa Von Wald, Ranjit John, Univ of Minnesota, Minneapolis, MN; Henri Roukoz, Univ Minnesota, Minneapolis, MN

1:15 PM

Q & A

# Abstract Rapid Fire Oral

## AC.RFO5 - Can We Sail the Ship to from Tempestuous Seas to Safe Harbor!

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 12:30 PM - 1:20 PM

12:30 PM

Angiographic Predictors of Outcome With Respect to Reperfusion Success of the Culprit Artery: CULPRIT SHOCK Angiographic Substudy

Pavel Overtchouk, Olivier Barthélémy, Marie Hauguel-Moreau, Sorbonne Univ, ACTION Study Group, INSERM UMRS_1166, Inst de Cardiologie (AP-HP), Paris, France; Paul Guedeney, Paris; Stephanie Rouanet, StatEthic, Levallois Perret, France; Georges Hage, Pitie Salpetriere Hosp, Paris, France; Michel Zeitouni, Duke Clinical Res Inst, Durham, NC; Benjamin Bertin, Sorbonne Univ, ACTION Study Group, INSERM UMRS_1166, Inst de Cardiologie (AP-HP), Paris, France; Delphine Brugier, Nicolas Vignolles, Action-Coeur, Paris, France; Sophie Galier, Mohamad El Kasty, Sorbonne Univ, ACTION Study Group, INSERM UMRS_1166, Inst de Cardiologie (AP-HP), Paris, France; Mathieu Kerneis, Heart Inst, Pitie Salpetriere Hosp, Paris 6 Univ, Paris, France; **Johanne Silvain** , CH Pitie Salpetriere, Paris, France; Jean Philippe Collet Jr., Inst de Cardiologie, Paris, France; Eric Vicaut, Inst de Cardiologie, Paris, France, Paris, France; Uwe Zeymer, Holger Thiele, Klinikum Ludwigshafen, Ludwigshafen; Gilles Montalescot, Hop Pitie Salpetriere, Paris, France

12:35 PM

Q & A

12:40 PM

Triple Antithrombotic Therapy With Warfarin or Dual Therapy With Dabigatran According to the Precise-Dapt Score in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: Insights From the Re-Dual Pci Trial

**Francesco Costa** , Policlinic "G Martino," Univ of Messina, Messina, Italy; Marco Valgimigli, Bern Univ Hosp, Messina, Italy; Philippe G Steg, FACT, an F-CRIN Network, DHU FIRE, Univ Paris Diderot, Paris, France; Deepak L. Bhatt, Brigham and Women's Hosp, Newton, MA; Stefan Hans Hohnloser, Goethe Univ Theodor Stern Kai, Frankfurt; Corinna Miede, HMS Analytical Software GmbH, Weimar (Lahn), Germany; Matias Nordaby, BI PHARMA GMBH & CO KG, Ingelheim; Gregory Y.H. Lip, Liverpool Ctr for Cardiovascular Science, Liverpool, United Kingdom; Jonas Oldgren, Uppsala Clinical Res Ctr, Uppsala, Sweden; Christopher P Cannon, Baim Inst for Clinical Res, Boston, MA

12:45 PM

Q & A

12:50 PM

Impact Of Simple Nutrition Index On The Long-term Mortality Of Patients With Acute Myocardial Infarction: Insight From A Prospective Multicenter Observational Study

**Atsushi Kikuchi** , Takahisa Yamada, Osaka General Medical Ctr, Osaka, Japan; Yasuhiko Sakata, Tohoku Univ Graduate Sch Med, Sendai, Japan; Shungo Hikoso, Osaka Univ Grad Sch of Med, Suita, Japan; Daisaku Nakatani, Osaka Univ Graduate Sch, Suita, Japan; Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Osaka General Medical Ctr, Osaka, Japan; Tsutomu Kawai, Osaka, Japan; Masahiro Seo, Osaka General Medical Ctr, Osaka City, Japan; Yasushi Sakata, Osaka Univ Grad Sch Med, Suita, Japan

12:55 PM

Q & A

1:00 PM

Impact of Imaging-Guided Emergency Percutaneous Coronary Intervention on Stent Strut Condition After Drug-Eluting Stents Implantation

**Takuya Nakamura** , Yutaka Goryo, Enomoto Masashi, Isojima Takuya, Takitsume Akihiro, Hiroyuki Kawata, Nara Prefecture General Medical Ctr, Nara, Japan

1:05 PM

Q & A

1:10 PM

Patients With a High Genetic Risk Score for Coronary Artery Disease May Receive Greater Benefit From Alirocumab Treatment in the ODYSSEY OUTCOMES Trial

Amy Damask, Regeneron Pharmaceuticals, Tarrytown, NY; Philippe Gabriel Steg, Hop Bichat, Paris, France; Gregory G Schwartz, Univ of Colorado Sch of Med, Aurora, CO; Michael Szarek, State Univ of New York, Brooklyn, NY; Emil Hagstrom, Uppsala Univ Hosp, Uppsala, Sweden; Lina Badimon, Autonomous Univ of Barcelona, Barcelona, Spain; Poulabi Banerjee, Garen Manvelian, Regeneron Pharmaceuticals, Tarrytown, NY; Sibylle Hess, Sanofi, Frankfurt, Germany; Goncalo R Abecasis, Aris Baras, **Charles Paulding** , Regeneron Pharmaceuticals, Tarrytown, NY; for the ODYSSEY OUTCOMES Investigators

1:15 PM

Q & A

# Abstract Rapid Fire Oral

## AT.RFO1 - Novel Lipid-Modulating Therapies and Targets for Atherosclerosis

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 12:30 PM - 1:20 PM

12:30 PM

A Novel Short Interfering Ribonucleic Acid Shows Potent and Sustained Reduction of Serum Lipoprotein (a) in Cynomolgus Monkeys

Manuela Aleku, Mona Eisermann, Kathrin Löffler, Sibylle Dames, Christian Frauendorf, Marie Wikstrom Lindholm, Steffen Schubert, **David Rider** , Silence Therapeutics GmbH, Berlin, Germany

12:35 PM

Q & A

12:40 PM

Long-Term Exposure to Elevated Lipoprotein(a) Levels Influences Human Longevity

**Benoit Arsenault** , William Pelletier, Univ Laval, Quebec, QC, Canada; Yannick Kaiser, Academic Medical Ctr, Amsterdam, Netherlands; Nicolas Perrot, Christian Couture, Univ Laval, Quebec, QC, Canada; Kay-Tee Khaw, Nicholas Wareham, Univ of Cambridge, Cambridge, United Kingdom; Yohan Bosse, Philippe Pibarot, Univ Laval, Quebec, QC, Canada; Erik S.G. Stroes, Academic Medical Ctr, Amsterdam, Netherlands; Patrick Mathieu, Sebastien Theriault, Univ Laval, Quebec, QC, Canada; S. Matthijs Boekholdt, Academic Medical Ctr, Amsterdam, Netherlands

12:45 PM

Q & A

12:50 PM

Oral Protease Proprotein Convertase Subtilisin-like Kexin Type 9 Antagonist: Direction to the Clinic as a Treatment for Hypercholesterolemia

**Nabil A Elshourbagy** , Shifa Biomedical Corp, Malvern, PA; Kavitha Godugu, Kazutoshi Fujioka, Weikun Li, Pharmaceutical Res Inst, Rensselaer, NY; Harold V Meyers, Sherin Abdel-Meguid, Shifa Biomedical Corp, Malvern, PA; Shaker Mousa, Pharmaceutical Res Inst, Rensselaer, NY

12:55 PM

Q & A

1:00 PM

Effects of a Neutralising Endothelial Lipase Monoclonal Antibody on Lipoprotein Metabolism in Nonhuman Primates and Healthy Volunteers

**Joe Grimsby** , AstraZenenca, Gaithersburg, MD; Judith Falloon, AstraZeneca, Gaithersburg, MD; Melissa Damschroder, AstraZenenca, Gaithersburg, MD; John Le Lay, AstraZeneca, Gaithersburg, MD; Glenn Carlson, AstraZenenca, Gaithersburg, MD; Tim Hummer, AstraZeneca, Gatithersburg, MD; Anton I Rosenbaum, ChaoYu Jin, AstraZenenca, South San Francisco, CA; Lan-Feng Tsai, Nicholas Bhagroo, William Cook, AstraZenenca, Gaithersburg, MD; David Han, Parexel, Glendale, CA; Sotirios Karathanasis, AstraZenenca, Gaithersburg, MD; Judith Hsia, AstraZeneca, McLean, VA; Boaz Hirshberg, AstraZenenca, Gaithersburg, MD

1:05 PM

Q & A

1:10 PM

Receptor-independent Ldl Macropinocytosis by Macrophages Contributes to the Pathogenesis of Atherosclerosis

**Huiping Lin** , Bhupesh Singla, Augusta Univ, Augusta, GA; Pushpankur Ghoshal, Mary Shaw, Augusta Univ, augusta, GA; David Fulton, Gabor Csanyi, Augusta Univ, Augusta, GA

1:15 PM

Q & A

# Abstract Rapid Fire Oral

## QU.RFO13 - Novel Methods of Risk Prediction

#### Science and Technology Hall A, Booth 605, Level 2

### Saturday, November 16, 2019, 12:30 PM - 1:20 PM

12:30 PM

Moderator

Sharon-lise Normand, Boston, MA

12:30 PM

Calibration and Discrimination of the Framingham Risk Score and the Pooled Cohort Risk Equations in a Canadian Primary Prevention Cohort

Dennis T Ko, Atul Sivaswamy, ICES, Toronto, ON, Canada; **Maneesh Sud** , Sunnybrook Health Sciences Ctr, Toronto, ON, Canada; Paymon Azizi, ICES, Toronto, ON, Canada; Gynter Kotrri, Univ of Toronto, Toronto, ON, Canada; Maria Koh, ICES, Toronto, ON, Canada; Douglas Lee, Univ Health Network, Toronto, ON, Canada; George Thanassoulis, McGill Univ Health Ctr, Mont-royal, QC, Canada; Idan Roifman, Sunnybrook Health Sciences Ctr, Toronto, ON, Canada; Karen Tu, ICES, Toronto, ON, Canada; Jacob A Udell, Women's Coll Hosp, Univ of Toronto, Toronto, ON, Canada; Harindra C Wijeysundera, Sunnybrook Health Science Ctr, Toronto, ON, Canada; Todd Anderson, Libin Cardiovascular Ctr of Alberta, Calgary, AB, Canada

12:40 PM

Risk Stratification to Improve the Benefit of Non-Invasive Cardiac Testing in Suspected Acute Coronary Syndrome

**Aniket A Kawatkar** , Adam L Sharp, Aileen Baecker, Kaiser Permanente Southern California, Pasadena, CA; Shaw Natsui, UCLA, Santa Monica, CA; Rita F Redberg, UCSF, San Francisco, CA; Ming Sum Lee, Kaiser Permanente, Los Angeles, CA; Maros Ferencik, OHSU, Portland, OR; Yi-Lin Wu, Ernest Shen, Chengyi Zheng, Visanee Musigdilok, Kaiser Permanente Southern California, Pasadena, CA; Benjamin Sun, Univ of Pennsylvania, Philadelphia, PA

1:00 PM

A New Multivariate Model for Safe Contrast Limits to Prevent Contrast Induced Nephropathy After Percutaneous Coronary Intervention

**Neal Yuan** , Cedars-Sinai Medical Ctr, Los Angeles, CA; Joseph Ebinger, Cedars-Sinai Heart Inst, Los Angeles, CA

1:10 PM

Deterioration Risk Detection for Acute Heart Failure Patients in the General and Cardiac Wards to Support Proactive Decision Making and Transitions of Care

**Kristen Tgavalekos** , Shreyas Ravindranath, Minnan Xu-Wilson, Philips Res North America, Cambridge, MA; Joel Fernandez, Univ of South Florida Morsani Coll of Med, Tampa, FL; Claire Y Zhao, Philips Res North America, Cambridge, MA

# Hall

## EP.HT.01 - Ask the Experts - How Do I Manage This Inherited Arrhythmia Disorder?

#### EP Central

### Saturday, November 16, 2019, 12:30 PM - 1:15 PM

12:30 PM

Moderator

Karine Guerrier, Memphis, TN

12:30 PM

Panel Participant

Elizabeth Kaufman, Cleveland, OH

12:45 PM

Panel Participant

Marco Valentin Perez, San Jose, CA

1:00 PM

Panel Participant

Elena Arbelo, BARCELONA, Spain

# Main Event

## CS.ME.102 - Distinguished Scientist Lecture

#### Nutter Theatre

### Saturday, November 16, 2019, 12:30 PM - 1:30 PM

12:30 PM

Distinguished Scientist Lecture

Joann E Manson, Boston, MA

# Moderated Digital Posters

## CA.MDP13 - Cell/Exosome Therapy

#### Moderated Posters 5, Science and Technology Hall

### Saturday, November 16, 2019, 12:30 PM - 1:10 PM

12:30 PM

WT1 as a Regulator of Adipocyte Derived Stem Cell Mediated Cardiac Revascularization and Regeneration

**Jihad Aljabban** , Ohio State Univ Coll of Med, Columbus, OH; Imad Aljabban, Penn State Coll of Med, Hershey, PA; Roman Camarda, Univ of California San Francisco, San Francisco, CA; Hussam Salhi, Ohio State Univ Coll of Med, Columbus, OH; Osama El-Sayed, Univ of Illinois Coll of Med, Chicago, IL; Dexter Hadley, Ramin E Beygui, Univ of California San Francisco, San Francisco, CA

12:35 PM

Q & A

12:40 PM

Cortical Bone Stem Cells Derived Exosomes Modulate Cardiac Immune Response to Enhance Reparative Processes After Injury

**Lena Ma** , Yijun Yang, Constantine Troupes, Marcus J. Wagner, Christopher Bryan, Eric Feldsott, Temple Univ, Philadelphia, PA; Jaslyn Johnson, Lewis Katz Sch of Med, Philadelphia, PA; Deborah Eaton, Temple Univ, Philadelphia, PA; Markus Wallner, Temple Univ Sch of Med, Philadelphia, PA; Hajime Kubo, Remus M Berretta II, Mohsin Khan, Temple Univ, Philadelphia, PA; Steven R Houser, iMMEDIATE Past President- AHA, Philadelphia, PA; Sadia Mohsin, Temple Univ, Philadelphia, PA

12:45 PM

Q & A

12:50 PM

Ploidy Stability of Murine Cardiac Stem Cells is Increased by Oxidative Stress

**Kathleen M Broughton** , San Diego State Univ, San Diego, CA; Carolina Esquer, San Diego State Univ, SAN DIEGO, CA; Mark Alan Sussman, San Diego State Univ, San Diego, CA

12:55 PM

Q & A

1:00 PM

Diabetes-Induced Impairment in Myocardial Reparative Function of Endothelial Progenitor Cell-Derived Exosomes

**Grace Huang** , Temple Univ, Philadelphia, PA; Venkata N Garikipati, Ctr for Translation Med, Philadelphia, PA; Maria Cimini, Vandana Mallaredy, Zhongjian Cheng, Chunlin Wang, Cindy Benedict, May Trungcao, Temple Univ, Philadelphia, PA; Raj Kishore, Temple Univ Sch of Med, Philadelphia, PA

1:05 PM

Q & A

# Moderated Digital Posters

## QU.MDP22 - Cost, Financial Toxicity and Value in Coronary Artery Disease Care

#### Moderated Posters 8, Science and Technology Hall

### Saturday, November 16, 2019, 12:30 PM - 1:20 PM

12:30 PM

Cardiologists' Use of Low-value Transthoracic Echocardiography With Care Utilization and Clinical Outcomes for Patients With Coronary Artery Disease

**Tharmegan Tharmaratnam** , Zachary Bouck, Women's Coll Hosp, Toronto, ON, Canada; Harindra Wijeysundera, Sunnybrook Health Sciences Ctr, Toronto, ON, Canada; Cindy X Yin, Women's Coll Hosp, Toronto, ON, Canada; Gillian C Nesbitt, Mount Sinai Hosp, Toronto, ON, Canada; Jeremy Edwards, St. Michael's Hosp, Toronto, ON, Canada; Kibar Yared, The Scarborough Hosp, Scarborough, ON, Canada; Brian Wong, Adina Weinerman, Sunnybrook Health Sciences Ctr, Toronto, ON, Canada; Paaladinesh Thavendiranathan, Univ of Toronto, Toronto, ON, Canada; Harry Rakowski, Toronto General Hosp, Toronto, ON, Canada; Paul Dorian, St Michaels Hosp, Toronto, ON, Canada; Geoff Anderson, Univ of Toronto, Toronto, ON, Canada; Peter Austin, Inst for Clinical Evaluative S, Toronto, ON, Canada; David Dudzinski, Massachusetts General Hosp, Belmont, MA; Dennis Ko, ICES, Toronto, ON, Canada; Rory Weiner, Massachusetts General Hosp, Boston, MA; Sacha Bhatia, Univ of Toronto, Toronto, ON, Canada

12:35 PM

Q & A

12:40 PM

Cardiology Curbside: A Novel Telephone Model of Efficient and Cost-Effective Delivery of Care

**Mary L Pavia** , Minneapolis Heart Inst Fndn, Minneapolis, MN; Richard Bae, Minneapolis Cardio Assoc, Minneapolis, MN; Steven M Bradley, Minneapolis Heart Inst, Minneapolis, MN; Marc C Newell, Minneapolis Heart Inst, Orono, MN; Craig Strauss, Minneapolis Heart Inst, Minneapolis, MN; Ross Garberich, Minneapolis Heart Inst. Fnd., Minneapolis, MN; Christopher Han, Chelsey Thomas, David G Hurrell, Minneapolis Heart Inst Fndn, Minneapolis, MN

12:45 PM

Q & A

12:50 PM

Scope of Financial Toxicity Among Older Medicare Adults With Atherosclerotic Cardiovascular Disease in the United States

**Gowtham R Grandhi** , MedStar Health Internal Med, Baltimore, MD; Reed Mszar, Yale Sch of Public Health, Manassas, VA; Javier Valero-Elizondo, Yale Univ, New Haven, CT; Rohan Khera, UT Southwestern Medical Ctr, Dallas, TX; Nihar R. Desai, Yale Sch of Med, New Haven, CT; Ron Blankstein, Brigham and Womens Hosp, Boston, MA; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; Salim S Virani, Michael E Debakey VA-Baylor, Bellaire, TX; Harlan M Krumholz, Yale Univ Schl Med, New Haven, CT; Khurram Nasir, Yale Sch of Med, New Haven, CT

12:55 PM

Q & A

1:00 PM

Predicting the Cost-Effectiveness of Cardiovascular Interventions Across Multiple Settings: A Model-based Approach to Guide Global Health Policy

**Saate S Shakil** , Katherine L Rosettie, Gregory A Roth, Lauryn Stafford, Marcia R Weaver, Univ of Washington, Seattle, WA

1:05 PM

Q & A

1:10 PM

Nationwide Trends in In-Hospital Outcomes Among Medicaid and Self-Pay Enrollees Undergoing Percutaneous Coronary Interventions

**Rushik Bhuva** , Geisinger Wyoming Valley Medical Ctr, Wilkes-Barre, PA; Rupak Desai, Atlanta VA Medical Ctr, Decatur, GA; Tarang Parekh, George Mason Univ, Fairfax, VA; Upenkumar Patel, Nassau Univ Medical Ctr, East Meadow, NY; Kartik Dhaduk, Westchester Medical Ctr, Valhalla, NY; Mir Zeeshan Ali Khan, St. Peters Univ Hosp, New Brunswick, NJ; Nazia Farheen, Lake America Family Physicians, Clermont, FL; Abhimanyu Ravalani, St. Peters Univ Hosp, New Brunswick, NJ; Rajesh Sachdeva, Morehouse Sch of Med, Atlanta VA Medical Ctr & Emory Univ Sch of Med, Atlanta, GA; Gautam Kumar, Emory Univ & Atlanta VA Medical Ctr, Decatur, GA

1:15 PM

Q & A

# Moderated Digital Posters

## IM.MDP7 - Don't Go Breaking My Heart: Heart Failure and Transplantation

#### Moderated Posters 3, Science and Technology Hall

### Saturday, November 16, 2019, 12:30 PM - 1:20 PM

12:30 PM

Cardiovascular Magnetic Resonance Imaging-Based Multivariable Risk Score for the Prediction of Heart Failure Admission or Death

**Aidan K Cornhill** , Steven Dykstra, Yoko Mikami, Univ of Calgary, Calgary, AB, Canada; Jacqueline Flewitt, Alberta Health Services, Calgary, AB, Canada; Michelle Seib, Peter Faris, Matthew James, Carmen Lydell, Andrew Howarth, Bobby Heydari, Nowell Fine, Univ of Calgary, Calgary, AB, Canada; Derek V Exner, Libin Cardiovascular Inst, Calgary, AB, Canada; Joon Lee, James White, Univ of Calgary, Calgary, AB, Canada

12:35 PM

Q & A

12:40 PM

Cardiac Remodeling Predicts Outcome for Patients With Stable Heart Failure: A Serial Cardiac Magnetic Resonance Imaging Study

**Lingyu Xu** , Univ of Alberta, Edmonton, AB, Canada; Kelvin Chow, Siemens Medical Solutions USA, Inc., Chicago, IL; Joseph Jeremie Pagano, Univ of Alberta, Edmonton, AB, Canada; Gavin Y. Oudit, Div of Cardiology, Mazankowski Alberta Heart Inst, Univ of Alberta, Edmonton, AB, Canada; Jason Ronald Dyck, Univ Alberta, Edmonton, AB, Canada; Mark Joseph Haykowsky, Univ of Texas at Arlington, Arlington, TX; James A White, Univ of Calgary, Calgary, AB, Canada; Justin Ezekowitz, Richard B Thompson, Ian Paterson, Univ of Alberta, Edmonton, AB, Canada; Alberta HEART Study Investigators

12:45 PM

Q & A

12:50 PM

Myocardial Remodelling Following Heart Failure Therapy Withdrawal in Patients With Dilated Cardiomyopathy and Improved Left Ventricular Ejection Fraction - Results From TRED-HF

**Brian Halliday** , Imperial Coll, London, London, United Kingdom; Vassilios Vassiliou, Royal Brompton Hosp, London; Rebecca Wassall, Imperial Coll, London, London, United Kingdom; Amrit Lota, Imperial Coll London, London; Zohya Khalique, Rick Wage, Gillian Smith, Imperial Coll, London, London, United Kingdom; Upasana Tayal, Royal Brompton Hosp, London; Daniel Hammersley, Royal Brompton Hosp, London, United Kingdom; Richard Jones, Imperial Coll, London, London, United Kingdom; John Baksi, Royal Brompton Hosp, London, Ukraine; Dudley J Pennell, Royal Brompton Hosp, London, United Kingdom; John G Cleland, Univ of Glasgow, Glasgow, United Kingdom; Sanjay Kumar Prasad, Royal Brompton Hosp, London, Ukraine

12:55 PM

Q & A

1:00 PM

Negative Synergism of Diabetes Mellitus and Obesity on the Myocardium in Patients With Heart Failure With Preserved Ejection Fraction: A Cardiovascular Magnetic Resonance Study

**Selcuk Kucukseymen** , Ulf Neisius, Connie W Tsao, Reza Nezafat, Beth Israel Deaconess Medical Ctr and Harvard Medical Sch, Boston, MA

1:05 PM

Q & A

1:10 PM

Prognostic Value of Cardiovascular Magnetic Resonance Feature-Tracking Global Longitudinal Strain in Heart Transplant Recipients

**Chetan Shenoy** , Univ of Minnesota, Minneapolis, MN; Simone Romano, Univ of Illinois, Chicago, Chicago, IL; Andrew Hughes, Osama Okasha, Prabhjot S Nijjar, Pratik Velangi, Mehmet Akcakaya, Cindy M Martin, Univ of Minnesota, Minneapolis, MN; Pablo Salazar, Afshin Farzaneh-Far, Univ of Illinois, Chicago, IL

1:15 PM

Q & A

# Moderated Digital Posters

## HF.MDP10 - Heart Failure III

#### Moderated Posters 4, Science and Technology Hall

### Saturday, November 16, 2019, 12:30 PM - 1:20 PM

12:30 PM

Moderator

Hemal H Patel, San Diego, CA

12:30 PM

Computational Protein Modeling to Engineer a C-X-C Chemokine Receptor Type 4 (CXCR-4) Agonist to Prevent Ischemic Heart Failure

**Patpilai Kasinpila** , Rohan Shad, Stanford Univ Medical Ctr, Stanford, CA; Vandon Duong, Stanford Univ, Stanford, CA; Robyn Fong, Stanford Univ Medical Ctr, Stanford, CA; Nicolas Quach, Stanford Univ, Stanford, CA; Sandra Kong, Stanford Univ Medical Ctr, Stanford, CA; Carla Perez, Possu Huang, Stanford Univ, Stanford, CA; William Hiesinger, Stanford Univ Sch of Med, Stanford, CA

12:35 PM

Q & A

12:40 PM

Preadipocytes are Decreased by Sympathetic Nerve Activity in Heart Failure

**Yusuke Takeda** , Oto Inoue, Ayano Nomura, Chiaki Goten, Shinichiro Takashima, Soichiro Usui, Kenji Sakata, Masa-Aki Kawashiri, Masayuki Takamura, Kanazawa Univ, Kanazawa, Japan

12:45 PM

Q & A

12:50 PM

The Long-Non-Coding RNA Snhg15 is Dsyregulated in Heart Failure and Interact With Alternative Splice Regulator Zranb2

**Yosif Manavski** , Christina Ott, Cardiovascular Regeneration, Frankfurt, Germany; Benjamin Meder, Cardiomyopathies, Heidelberg, Germany; Jes-Niels Boeckel, Cardiology, Leipzig, Germany; Hugo Katus, Cardiology, Heidelberg, Germany; Christian Bär, Molecular and Translational Therapeutic Strategies, Frankfurt Am, Germany; Thomas Thum, Molecular and Translational Therapeutic Strategies, Hannover, Germany; Andreas M Zeiher, Klinikum d. J. W Goethe-Univ, Frankfurt Am Main; Tina Lucas, Cardiovascular Regeneration, Frankfurt, Germany; Stefanie Dimmeler, Cardiovascular Regeneration, Frankfurt Am Main, Germany

12:55 PM

Q & A

1:00 PM

Assessment of Left Ventricle Myocardial Deformation in a Hemorrhagic Shock Swine Model by Two-Dimension Speckle Tracking Echocardiography

**Henrique Doria De Vasconcellos** , Johns Hopkins, Baltimore, MD; Karen S Saad, Univ Federal do Vale do Sao Francisco, Petrolina, Brazil; Denise A Otsuki, Faculdade de Medicina - Univ de Sao Paulo, Sao Paulo, Brazil; Paulo Saad, Univ Federal do Vale do Sao Francisco, Petrolina, Brazil; Luisa Ciuffo, Johns Hopkins, Baltimore, MD; Anderson C Armstrong, Univ Federal do Vale do Sao Francisco, Baltimore, MD; Joao A Lima, Johns Hopkins Univ, Baltimore, MD; Edna F s Frasson de Souza Montero, Faculdade de Medicina - Univ de Sao Paulo, Sao Paulo, Brazil

1:05 PM

Q & A

1:10 PM

Insulin Like Growth Factor Binding Protein 7 Cardiac Structure and Function in Acute Dyspneic Patients With and Without Acute Heart Failure

**Arzu Kalayci** , Beth Israel Deaconess Medical Ctr, Boston, MA; William Peacock, Baylor Coll Med, Houston, TX; John Nagurney, Massachusetts General Hosp, Boston, MA; Judd Hollander, Thomas Jefferson Univ Hosp, Philadelphia, PA; Phillip Levy, Wayne State Univ IBIO, Detroit, MI; Adam Singer, Stony Brook Univ Hosp, New York, NY; Nathan Shapiro, Beth Israel Deaconess Medical Ctr, Boston, MA; Richard Cheng, Univ of Washington, Seattle, WA; Chad M Cannon, Univ of Kansas Medical Ctr, Kansas, KS; Andra Blomkalns, The Univ of Texas Southwestern Medical Ctr, Dallas, TX; Elizabeth L Walters, Loma Linda Univ Medical Ctr, Loma Linda, CA; Robert Christenson, Univ of Maryland Med Sch, Baltimore, MD; Annabel Chen-Tournoux, Dr Annabel Chen-Tournoux Inc, Montreal, QC, Canada; Richard Nowak, Henry Ford Hosp, Detroit, MI; Mark Lurie, Torrance Memorial Medical Ctr, Torrance, CA; Peter Pang, Indiana Univ, Indianapolis, IN; Serge Masson, Roche Diagnostics Ltd, Rotkreuz; C Michael Gibson, Beth Israel Deaconess Medical Ctr, Boston, MA; Hanna Gaggin, Mass General Hosp, Boston, MA; James Januzzi, Massachusetts General Hosp, Wellesley Hills, MA

1:15 PM

Q & A

# Moderated Digital Posters

## AC.MDP1 - Improving Outcomes Following Acute Myocardial Injury: How Do We Get Better?

#### Moderated Posters 1, Science and Technology Hall

### Saturday, November 16, 2019, 12:30 PM - 1:20 PM

12:30 PM

Long-term Outcomes in Acute Myocardial Infarction Patients With Cardiogenic Shock: A Landmark Sub-analysis From Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (j-minuet) Registry

**Hideki Wada** , Juntendo Univ Shizuoka Hospit, Izunokuni Shizuoka, Japan; Manabu Ogita, Juntendo Univ Shizuoka, Izunokuni, Japan; Satoru Suwa, Juntendo Univ Shizuoka Hosp, Izunokuni, Japan; Koichi Nakao, Saiseikai Kumamoto Hosp, Kumamoto, Japan; Yukio Ozaki, Fujita Health Univ Hosp, Toyoake, Japan; Kazuo Kimura, Yokohama City Univ Medical Ctr, Yokohama, Japan; Junya Ako, Kitasato Univ, Kanagawa, Japan; Teruo Noguchi, Natl Cardiovascular Ctr, Suita, Japan; Satoshi Yasuda, Natl Cereb Cardiovascular Ctr, Osaka, Japan; Kazuteru Fujimoto, Natl Hosp Organization Kumamoto Medical Ctr, Kumamoto, Japan; Yasuharu Nakama, Hiroshima City Hosp, Hiroshima, Japan; Takashi Morita, Osaka General Medical Ctr, Osaka, Japan; Wataru Shimizu, Nippon Medical Sch, Tokyo, Japan; Yoshihiko Saito, Nara Medical Univ, Kashihara, Japan; Atsushi Hirohata, Sakakibara Heart Institue, Okayama, Japan; Yasuhiro Morita, Ogaki Municipal Hosp, Ogaki-shi,Gifu, Japan; Inoue Teruo, Dokkyo Medical Univ, Mibu, Tochigi, Japan; Atsunori Okamura, Sakurabashi Watanabe Hosp, Osaka, Japan; Toshiaki Mano, Kansai Rosai Hosp, Amagasaki, Japan; Kazuhito Hirata, Okinawa Chubu Hosp, Uruma-shi,Okinawa, Japan; Kengo Tanabe, Mitsui Memorial Hosp, Tokyo, Japan; Yoshisato Shibata, Miyazaki Medical Association Hosp, Miyazaki, Japan; Mafumi Owa, Suwa Red Cross Hosp, Suwa, Japan; Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan; Hiroshi Funayama, Omiya Medical Ctr, Saitama, Japan; Nobuaki Kokubu, Sapporo Medical Univ, Sapporo, Japan; Ken Kozuma, Teikyo Univ, Tokyo, Japan; Shiro Uemura, Kawasaki Medical Sch, Kurashiki, Japan; Tetsuya Toubaru, Sakakibara Heart Inst, Fuchu, Tokyo, Japan; Keijirou Saku, Fukuoka Univ Sch of Med, Fukuoka, Japan; Shigeru Ohshima, Gunma Prefectural Cardiovascular Ctr, Maebashi, Gunma, Japan; Kunihiro Nishimura, Yoshihiro Miyamoto, Natl Cerebral and Cardiovascular Ctr, Suita, Osaka, Japan; Hisao Ogawa, Natl Cerebral and Cardiovascular Ctr, Suita Osaka, Japan; Masaharu Ishihara, Hyogo Coll of Med, Nishinomiya, Hyogo, Japan

12:35 PM

Q & A

12:40 PM

30-Day Readmission Following Non-ST Elevated Myocardial Infarction in Patients Who Did Not Have Percutaneous Coronary Intervention: Insight From Nationwide Readmission Database

Birendra Amgai, Interfaith Medical Ctr, Brooklyn, NY; Adrija Hajra, Jacobi Medical Ctr, New York, NY; Neel Patel, Interfaith Medical Ctr, New York, NY; **Dhrubajyoti Bandyopadhyay** , Mount Sinai St Luke's Roosevelt, New York, NY, NY; Sandipan Chakraborty, Interfaith Medical Ctr, Brooklyn, NY; Soniya Koirala, Tribhuvan Univ Teaching Hosp, Kathmandu, Nepal; Tauseef Akhtar, J H Stroger Hosp of Cook County, Chicago, IL; Richa Sharma, Columbia Presbyterian, New York, NY; Eyal Herzog, Mount Sinai St Luke's Roosevelt, New York, NY

12:45 PM

Q & A

12:50 PM

Long-term Outcomes in Patients With Pregnancy Related vs. Non-pregnancy Related Spontaneous Coronary Artery Dissection: An International Multi-center Collaborative Study

SCAD Collaborative Study Group; David Adlam, Univ of Leicester, Leicester; Azza M Ahmed, Mayo Clinic, Eau Claire, WI; Abtehale Al-Hussaini, Imperial Coll London, London, United Kingdom; Sara Bouajila, Stanford Cardiovascular Inst, Stanford, CA; Eric KH Chow, Stanford Sch of Med, Palo Alto, CA; Katharine Edwards, Stanford Sch of Med, Stanford, CA; Sharonne N Hayes, Mayo Clinic, Rochester, MN; M. Ihsan Kaadan, Massachusetts General Hosp, Boston, MA; Rajani Kaimal, Stanford Sch of Med, Palo Alto, CA; Esther Sh Kim, Vanderbilt Univ Medical Ctr, Nashville, TN; Pascal Motreff, Univ Hosp Clermont, Clermont ferrand, France; Nalin Natarajan, Univ Hosp Of Leicester NHS Trust, Leicester, United Kingdom; **Vedant Satish Pargaonkar** , Stanford Sch of Med, Stanford, CA; Nilesh J Samani, Glenfield Hosp, Leicester, United Kingdom; Jacqueline Saw, Vancouver Gen Hosp, Vancouver, BC, Canada; Andrew Starovoytov, Univ of British Columbia, Vancouver, BC, Canada; Jennifer A Tremmel, Stanford Univ Medical Ctr, Stanford, CA; Marysia Tweet, Coll Med Mayo Clinic Rochester, Rochester, MN; Alice Wood, Univ of Leicester, Leicester, United Kingdom; Malissa J Wood, Massachsetts General Hosp, Boston, MA

12:55 PM

Q & A

1:00 PM

**Impact of a Reduced Ejection Fraction on Short And Long-term Outcome in Patients With** ST **-elevation Myocardial Infarctions in Patients With and Without Cardiogenic Shock- Results From a German** STEMI-registry

**Johannes Schmucker** , Bremer Inst für Herz- und Kreislaufforschung am Klinikum Links der weser, Bremen, Germany; Andreas Fach, Rico Osteresch, Bremer Inst für Herz- und Kreislaufforschung am Klinikum Links der Weser, Bremen, Germany; Tina Retzlaff, Stephan Michel, Daniela Garstka, Tineke Wettwer, Bremer Inst für Herz- und Kreislaufforschung am Klinikum Links der weser, Bremen, Germany; Rainer Hambrecht, Bremer Inst für Herz- und Kreislaufforschung am Klinikum Links der Weser, Bremen, Germany; Harm Wienbergen, Bremer Inst für Herz- und Kreislaufforschung am Klinikum Links der weser, Bremen, Germany

1:05 PM

Q & A

1:10 PM

Effect of Alirocumab in Patients With Recent Acute Coronary Syndrome According to Renal Function: A Prespecified Analysis of the ODYSSEY OUTCOMES Trial

**Jose Tunon** , IIS-Fundacion Jimenez Diaz, Madrid, Spain; Philippe Gabriel Steg, Hop Bichat, Paris, France; Deepak L Bhatt, Brigham and Women's Hosp, Boston, MA; Vera A Bittner, Univ of Alabama at Birmingham, Birmingham, AL; Rafael Diaz, Estudios Clínicos Latinoamérica, Rosario, Argentina; Shaun Geoffrey Goodman, St. Michael's Hosp, Toronto, ON, Canada; J Wouter Jukema, Leiden Univ Medical Ctr, Leiden, Netherlands; Yong-Un Kim, Sanofi, Paris, France; Qian H Li, Regeneron Pharmaceuticals, Tarrytown, NY; Christian Mueller, Univ Hosp Basel, Basel, Switzerland; Alexander Parkhomenko, M.D. Strazhesko Inst of Cardiology of AMS of Ukraine, Kiev, Ukraine; Robert Pordy, Regeneron Pharmaceuticals, Tarrytown, NY; Piyamitr Sritara, Ramathibodi Hosp, Bangkok, Thailand; Michael Szarek, State Univ of New York, Brooklyn, NY; Harvey D White, Auckland City Hosp, Auckland, New Zealand; Andreas M Zeiher, Goethe Univ, Frankfurt Am Main, Germany; Gregory G Schwartz, Univ of Colorado Sch of Med, Aurora, CO; for the ODYSSEY OUTCOMES Investigators

1:15 PM

Q&A

# Moderated Digital Posters

## EA.MDP4 - Is Use of Artificial Intelligence Helpful in Solving Arrhythmia Challenges?

#### Moderated Posters 2, Science and Technology Hall

### Saturday, November 16, 2019, 12:30 PM - 1:20 PM

12:30 PM

Moderator

Cynthia Tracy, Washington, DC

12:30 PM

Machine Learning Using Electronic Health Records to Predict 6-Month Incident Atrial Fibrillation

Premanand Tiwari, Kathryn L Colborn, Derek E Smith, Fuyong Xing, Debashis Ghosh, **Michael A Rosenberg** , Univ of Colorado, Aurora, CO

12:35 PM

Q & A

12:40 PM

A Deep Neural Network for Predicting Incident Atrial Fibrillation Directly From 12-Lead Electrocardiogram Traces

**Sushravya M Raghunath** , Alvaro Ulloa Cerna, Linyuan Jing, David vanMaanen, Geisinger, Danville, PA; Joshua Victor Stough, Bucknell Univ, Lewisburg, PA; Dustin Hartzel, Joseph Leader, Geisinger, Danville, PA; Christopher Good, Medicor Associates, Inc, Erie, PA; Brandon K Fornwalt, Christopher M Haggerty, Geisinger, Danville, PA

12:45 PM

Q & A

12:50 PM

Machine Learning to Guide Dose Decisions for Dofetilide

Andrew E Levy, Minakshi Biswas, Rachel Weber, Univ of Colorado, Aurora, CO; Khaldoun Tarakji, Mina K Chung, Cleveland Clinic, Cleveland, OH; Peter Alexander Noseworthy, Mayo Clinic, Rochester, MN; Christopher Newton-Cheh, Massachusetts General Hosp, Boston, MA; **Michael A Rosenberg** , Univ of Colorado, Aurora, CO

12:55 PM

Q & A

1:00 PM

Machine Learning of 12-lead Qrs Waveform Patterns to Identify Cardiac Resynchronization Therapy Patients With Differential Outcomes

**Albert K Feeny** , Case Western Reserve Univ, Cleveland, OH; John Rickard, Cleveland Clinic Fndn, Cleveland Hts, OH; Kevin M Trulock, Divyang Patel, Cleveland Clinic Fndn, Cleveland, OH; Saleem Toro, Cleveland Clinic Fndn, Cleveland Heights, OH; Laurie Ann Moennich, Cleveland Clinic Fndn, Cleveland, OH; Niraj Varma, Cleveland Clinic, Cleveland, OH; Mark J Niebauer, Eiran Z Gorodeski, Richard Allen Grimm, John Barnard, Cleveland Clinic Fndn, Cleveland, OH; Anant Madabhushi, Case Western Reserve Univ, Cleveland, OH; Mina K Chung, Cleveland Clinic Fndn, Cleveland, OH

1:05 PM

Q & A

1:10 PM

Artificial Intelligence Based Platform Enables Faster Ambulatory Electrocardiogram Analysis With Equivalent Clinical Accuracy Compared to Traditional Solution

**Laurent Fiorina** , Cardiovascular Inst Paris-Sud, Hôpital Jacques Cartier, Ramsay, Massy, France; Eloi Marijon, European Hosp Gerorges Pompidou, Paris, France; Carole Maupain, HU Pitié-Salpêtrière, Paris, France; Charlene Coquard, Cardiovascular Inst Paris-Sud, Hôpital Jacques Cartier, Ramsay, Massy, France; Louis Larnier, HU Pitié-Salpêtrière, paris, France; Julien Rischard, European Hosp Gerorges Pompidou, Paris, France; Aurelie Bourmaud, Robert Debré Hosp, Paris, France; Jia Li, Cardiologs Technologies, Paris, France; Mina Ait Said, Jerome Horvilleur, Jerome Lacotte, Cardiovascular Inst Paris-Sud, Hôpital Jacques Cartier, Ramsay, Massy, France; Alice Maltret, Hosp Necker Enfants Malades, Paris, France; Vladimir Mannenti, Fiorella Salerno, Cardiovascular Inst Paris-Sud, Hôpital Jacques Cartier, Ramsay, Massy, France; Christophe Gardella, Cardiologs Technologies, Paris, France

1:15 PM

Q & A

# Moderated Digital Posters

## GE.MDP16 - Metabolomics and Proteomics

#### Moderated Posters 6, Science and Technology Hall

### Saturday, November 16, 2019, 12:30 PM - 1:20 PM

12:30 PM

Metabolomic Profiling and Heart Failure Risk in the Atherosclerosis Risk in Communities Study

**Bing Yu** , Wenshuang Wang, Univ of TX Health Sci Ctr Houston, Houston, TX; Brian Claggett, Brigham and Women's Hosp, Boston, MA; Sunil K. Agarwal, Johns Hopkins Univ, Baltimore, MD; David Aguilar, Univ of Texas Health Science, Houston, TX; Patricia Chang, Univ of North Carolina, Chapel Hill, NC; Laura R Loehr, Univ North Carolina Chapel Hill, Chapel Hill, NC; Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD; Joseph Rossi, UNC Sch of Med, Chapel Hill, NC; Stuart D Russell, Duke Univ Medical Ctr, Raleigh, NC; Richard Stacey, Wake Forest Univ, Winston Salem, NC; Gerardo M Heiss, Univ North Carolina, Chapel Hill, NC; Eric Boerwinkle, UTHealth, Houston, TX; Amil M Shah, Brigham and Womens Hosp, Boston, MA

12:35 PM

Q & A

12:40 PM

Prioritization of Post-Myocardial Infarction Heart Failure Targets Using Large-Scale Plasma Proteomics and Genome-Wide Single-Cardiac Cell Transcriptomics

**Mark Y Chan** , Motakis Efthymios, Sock-hwee Tan, Matthew Ackers Johnson, Natl Univ of Singapore, Singapore, Singapore; Kelvin See, Genome Inst of Singapore, Singapore, Singapore; John Pickering, Univ of Otago Christchurch, Christchurch; Richard Troughton, Christchurch Hosp, Christchurch, New Zealand; Chris J Pemberton, Univ of Otago, Christchurch, New Zealand; Hee Hwa Ho, Tan Tock Seng Hosp, Singapore, Singapore; Lieng Ling, Natl Univ of Singapore, Singapore; Wern Miin Soo, Natl Univ Heart Ctr Singapore, Rochester, MN; Chester L Drum, Natl Univ of Singapore, Singapore, Singapore; Siang Chew Chai, Changi General Hosp, Singapore, Singapore; Alan Fong, Sarawak General Hosp, Sarawak, Malaysia; Joshua Loh, Chi Hang Lee, Natl Univ Heart Ctr, Singapore, Singapore; Roger Foo, Cardiovascular Res Inst, Singapore; Anna P Pilbrow, Univ Otago Chch, Christchurch, New Zealand; Arthur Mark Richards, Natl Univ of Singapore, Singapore, Singapore

12:45 PM

Q & A

12:50 PM

The Effects of the PCSK9 R46L Genetic Variant on the Human Plasma Proteome

**Mark Benson** , Beth Israel Deaconess Medical Ctr, Boston, MA; Qiong Yang, Boston Univ Sch of Public Health, Boston, MA; Debby Ngo, Beth Israel Deaconess, Boston, MA; Ruibo Zhang, Boston Univ Sch of Public Health, Boston, MA; Dongxiao Shen, Sumita Sinha, Laurie Farrell, Beth Israel Deaconess Medical Ctr, Boston, MA; Vasan S Ramachandran, Framingham Heart Study, Framingham, MA; Martin Larson, Boston Univ, boston, MA; Thomas J Wang, Vanderbilt Univ Medical Ctr, Nashville, TN; Robert E Gerszten, Beth Israel Deaconess Medical Ctr, Boston, MA

12:55 PM

Q & A

1:05 PM

Q & A

1:10 PM

Lactobacillus Plantarum **299v Supplementation Results in Anti-Inflammatory Changes in Mononuclear Cell Gene Expression in Men With Stable Coronary Artery Disease Who Do Not Drink Alcohol Daily**

**Benjamin C Hofeld** , Venkata Puppala, Kwang Woo Ahn, Amberly Anger, Medical Coll of Wisconsin, Milwaukee, WI; Mamatha Kakarla, Medical Coll of Wisonsin, Milwaukee, WI; Jingli Wang, Michael J Tanner, Elise Nelton, John E Baker, Nita H Salzman, Martin J Hessner, Michael E Widlansky, Medical Coll of Wisconsin, Milwaukee, WI

1:15 PM

Q & A

# Moderated Digital Posters

## EP.MDP19 - Non-Cardiac Comorbidities, Inflammation and CVD Risk

#### Moderated Posters 7, Science and Technology Hall

### Saturday, November 16, 2019, 12:30 PM - 1:20 PM

12:30 PM

Moderator

Brendan M Everett, Boston, MA

12:30 PM

Immune Cells and the Risk of Cardiovascular Disease: Prospective Results From the Vacs Study

**Suman Kundu** , Vanderbilt Univ Medical Ctr, Nashville, TN; Matthew S Freiberg, Vanderbilt Univ, Nashville, TN; Russell Tracy, Univ of Vermont, Colchester, VT; Meredith Duncan, Vanderbilt Univ Medical Cntr, Nashville, TN; Kaku So-Armah, Boston Univ, Boston, MA; Wyatt J. McDonnell, Vanderbilt Univ Medical Ctr, Nashville, TN; John Koethe, Vanderbilt Univ Medical Cente, Nashville, TN; Hilary A. Tindle, Vanderbilt Univ Medical Ctr, Nashville, TN; Amy Justice, Yale Sch of Public Health, West Haven, CT; Margaret Doyle, Univ of Vermont, Colchester, VT

12:35 PM

Q & A

12:40 PM

Fat Distribution, Inflammatory Biomarkers, and Cardiometabolic Risk in Young Adults: The Avon Longitudinal Study of Parents and Children

**Scott T Chiesa** , UCL, London, United Kingdom; Marietta Charakida, Univ Coll London, London, United Kingdom; Alicja Rapala, UCL, London, United Kingdom; Kaitlin H Wade, Univ of Bristol, Bristol, United Kingdom; Devina J Bhowruth, UCL, London, United Kingdom; Justin D Roberts, Anglia Ruskin Univ, Cambridge, United Kingdom; Vivek Muthurangu, Great Ormond Street Hosp, London, United Kingdom; Naveed Sattar, Univ of Glasgow, Glasgow, United Kingdom; Alun D Hughes, UCL, London, United Kingdom; Nicholas Timpson, Univ of Bristol, Bristol, United Kingdom; John E Deanfield, UCL, London, United Kingdom

12:45 PM

Q & A

12:50 PM

The Association of the Novel Inflammatory Marker Glyc a and Incident Heart Failure and Its Subtypes of Preserved and Reduced Ejection Fraction: The Multi-ethnic Study of Atherosclerosis

**Sunyoung Jang** , Oluseye Ogunmoroti, Johns Hopkins Univ Sch of Med, Baltimore, MD; Vishal N Rao, Duke Univ Sch of Med, Durham, NC; Oluwaseun E Fashanu, Saint Agnes Hosp, Baltimore, MD; Di Zhao, Johns Hopkins Univ, Baltimore, MD; Martin Tibuakuu, St. Luke's Hosp, Chesterfield, MO; James D Otvos, LabCorp, Morrisville, NC; Eve-Marie Benson, Chiadi Ericson Ndumele, Pamela Ouyang, Johns Hopkins Univ Sch of Med, Baltimore, MD; Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD

12:55 PM

Q & A

1:00 PM

Cardiovascular Outcomes in Patients With Ankylosing Spondylitis in a Population Based-Study

**John B Kostis** , Davit Sargsyan, Rutgers Robert Wood Johnson Medical Sch, New Brunswick, NJ; Javier Cabrera, Rutgers Univ, New Brunswick, NJ; Mohammed Fahim, Traymon Beavers, Stavros Zinonos, William J. Kostis, Rutgers Robert Wood Johnson Medical Sch, New Brunswick, NJ; For the Myocardial Infarction Data Acquisition System Study Group

1:05 PM

Q & A

1:10 PM

Cardiovascular Outcomes in Patients With Mitochondrial Disease in the United States: A Propensity Score Analysis

**Tran Nguyen** , The George Washington Univ, Washington, DC; Talal Alzahrani, George Washington Univ, Arlington, VA; Joseph Krepp, The George Washington Univ, Washington, DC

1:15 PM

Q & A

# Hall

## HT.01 - Careers in Health Tech: Advice from the Front Lines

#### Health Innovation Pavilion, Heart Hub, Science and Technology Hall, Level 2

### Saturday, November 16, 2019, 1:00 PM - 2:00 PM

1:00 PM

Moderator

Pierre Elias, New York, NY

1:00 PM

Moderator

Eric Peterson, Durham, NC

1:00 PM

Invited Presenter

Michael V McConnell, S San Fran, CA

1:00 PM

Invited Presenter

Maulik Majmudar, Boston, MA

1:00 PM

Invited Presenter

Bimal R Shah, Durham, NC

# Simulation

## SIM.04 - Interactive Digital iWall Experiential Learning

#### Simulation Zone - Heart Hub, Hall C

### Saturday, November 16, 2019, 1:00 PM - 2:00 PM

1:00 PM

Invited Presenter

Tina Baykaner, Palo Alto, CA

# Expert Theater

## ET.04 - Amgen, Inc.

#### Learning Studio 1, Booth # 5

### Saturday, November 16, 2019, 1:15 PM - 2:00 PM

This is not a CME/CE certified session

# Expert Theater

## ET.05 - Boehringer Ingelheim Corporation

#### Game Central, Booth # 6

### Saturday, November 16, 2019, 1:15 PM - 2:00 PM

This is not a CME/CE certified session

# Expert Theater

## ET.06 - Novartis Pharmaceuticals Corp.

#### Learning Studio 2, Booth # 7

### Saturday, November 16, 2019, 1:15 PM - 2:00 PM

This is not a CME/CE certified session

# Abstract Poster Session

## IM.APS.03 - Advances in Echocardiography

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4164

Reasons for Disagreement Between Screening and Standard Echocardiography in Primary Care: Data From the PROVAR+ Study

**Bruno R Nascimento** , Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Andrea Z beaton, Cincinnati Childrens Hosp Medic, Cincinnati, OH; Maria Do Carmo Pereira Nunes, UFMG, Belo Horizonte, Brazil; Kaciane K Oliveira, Lara C Rabelo, Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Marcia Barbosa, Hosp Socor, Belo Horizonte, Brazil; Adriana C Diamantino, Rua Herculano De Freitas 151, Belo Horizonte Mg, Brazil; Breno D Rezende, Clara L Fraga, Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Laura Olivieri, Children's Natl Medical Ctr, Washington, DC; Alison T Reese, Children´s Natl Health System, Washington, DC; Mariana D Mata, Augusto F Pereira, Waydder Antônio A Costa, Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Antonio L Ribeiro, UFMG, Belo Horizonte, Brazil; Craig A Sable, Children's Natl Medical Ctr, Potomac, MD

1:30 PM

Board # 4165

Catheter Ablation Lesion Mapping With Intracardiac Echocardiography in Canines and Humans

**Vincent Sayseng** , Columbia Univ, New York, NY; Julien Grondin, Columbia Univ Medical Campus, New York, NY; Christopher Grubb, Columbia Univeristy Medical Ctr, New York, NY; Maryam Basij, Mohammad Mehrmohammadi, Wayne State Univ, Detroit, MI; Vivek Iyer, Columbia Univ Medical Ctr, New York, NY; Daniel Y Wang, Montefiore-White Plains Hosp, White Plains, NY; Hasan Garan, New York Presbyterian Medical Ctr, New York, NY; Elaine Wan, Columbia Univ Medical Ctr, New York, NY; Elisa Konofagou, Columbia Univ, New York, NY

1:30 PM

Board # 4166

Prognostic Utilization of Carotid Arterial Strain in High Risk Population and Preserved Ejection Fraction Heart Failure: Mechanistic Insights From Vascular Deformations

Kuo-Tzu Sung, MacKay Memorial Hosp, Taipei City, Taiwan; Kevin Ning Zhou, Williams Coll, MA, MA; Chih Hsuan Yen, Cheng-Huang Su, Ping-Ying Lee, Ta-Chuan Hung, Jui-Peng Tsai, Cheng-Ting Tsai, Charles Jia-Yin Hou, Hung-I Yeh, **Chung-Lieh Hung** , MacKay Memorial Hosp, Taipei City, Taiwan

1:30 PM

Board # 4167

Prosthetic Aortic Graft Replacement of the Ascending Thoracic Aorta Augments Distensibility of the Native Descending Aorta Assessed Via Circumferential Vessel Wall Strain

**Maria Chiara Palumbo** , Weill Cornell Medical Coll, New York, NY; Lisa Rong, Weill Cornell Med, New York, NY; Pedram Navid, New York Presbyterian Hosp, New York, NY; Abbas Emaminia, Columbia, New York, NY; Jiwon Kim, Weill Cornell Med, New York, NY; Yadong Wang, Cornell Univ, Ithaca, NY; Alberto Redaelli, Politecnico di Milano, Milan, Italy; Mary J Roman, Richard B Devereux, Weill Cornell Med, New York, NY; Leonard N Girardi, NYPH - Weill Cornell Med, New York, NY; Mario Gaudino, Weill Cornell Med, New York, NY; Jonathan W Weinsaft, Weill Cornell Medical Coll, Scarsdale, NY

1:30 PM

Board # 4168

Cardiac Microstructural Abnormalities Confer Differential Effects on Heart Failure Risk by Sex

**Emmanuella Demosthenes** , Brigham and Women's Hosp, Boston, MA; Gerran Salto, Brigham and Women's Hosp, Framingham, MA; Ewa Osypiuk, Plamen Stantchev, Boston Univ, Framingham, MA; Elizabeth H Kim, Cedars-Sinai Medical Ctr, Los Angeles, CA; Pranoti Hiremath, Johns Hopkins Med, Baltimore, MD; Susan Cheng, Cedars-Sinai Medical Ctr, Los Angeles, CA

1:30 PM

Board # 4169

Effect of Diabetes and Hypertension on Subclinical Left Ventricular Systolic Dysfunction in a Population-Based Cohort

**Carlo Mannina** , Zhezhen Jin, Cesare Russo, Shunichi Homma, Mitchell S.V. Elkind, Columbia Univ, New York, NY; Tatjana Rundek, Univ of Miami, Miami, FL; Tetz C. Lee, Kenji Matsumoto, Sofia Shames, Columbia Univ, New York, NY; Ralph L. Sacco, Univ of Miami, Miami, FL; Marco Di Tullio, Columbia Univ, New York, NY

1:30 PM

Board # 4170

Multimodal in vivo Imaging Highlights Novel Features of Cardiovascular Abnormalities in a New Mouse Model for Williams Syndrome

**Jeroen Essers** , Nicole van Vliet, Yanto Ridwan, Laurens Bosman, Chris de Zeeuw, Erasmus MC, Rotterdam, Netherlands

1:30 PM

Board # 4171

Myocardial Force-Velocity Accurately Differentiates Amyloid From Hypertensive Cardiomyopathy

**Waddy Gonzalez** , Andrea Furlani, Montefiore Medical Ctr, Bronx, NY; Ephraim Leiderman, Jacobi Medical Ctr, Bronx, NY; Mario J Garcia, Montefiore Medical Ctr, Bronx, NY

1:30 PM

Board # 4172

Right Ventricular Geometry and Exercise Performance in Group 2 Pulmonary Hypertension

**Giacomo D'Alesio** , IRCCS Policlinico San Donato, Milano, Italy; Francesco Migliavacca, Jose Matas, Politecnico di Milano, Milano, Italy; Francesco Bandera, IRCCS Policlinico San Donato, San Donato, Italy; Maurizio Losito, Eleonora Alfonzetti, Greta Ghizzardi, Marco Guazzi, Policlinico San Donato, San Donato, Italy

1:30 PM

Poster Professor

Andreea Dragulescu, Toronto, ON, Canada

1:30 PM

Board # 4174

Novel Multiparametric Echocardiographic Approach for Right Ventricular Hypertrophy as Demonstrated by Cardiac Magnetic Resonance

**Jonathan Kochav** , Jennifer Chen, Weill Cornell Medical Ctr, New York, NY; Lola Xie, Memorial Sloan Kettering Cancer Ctr, New York, NY; Michael Villanueva, Jonathan W Weinsaft, Weill Cornell Medical Ctr, New York, NY; Richard B Devereux, Weill Cornell Med, New York, NY; Jiwon Kim, Weill Cornell Medical Ctr, New York, NY

1:30 PM

Board # 4175

Pre-Procedural Evaluation of Circumferential Aortic Strain With Transesophageal Echocardiography: A Validation Study

**Maria Chiara Palumbo** , Samantha Huynh, Richard B Devereux, Jiwon Kim, Weill Cornell Med, New York, NY; Leonard N Girardi, NYPH - Weill Cornell Med, New York, NY; Mario Gaudino, Weill Cornell Med, New York, NY; Jonathan W Weinsaft, Weill Cornell Medical Coll, Scarsdale, NY; Lisa Rong, Weill Cornell Med, New York, NY

# Abstract Poster Session

## PH.APS.02 - Advances in Translational PAH and RV Dysfunction

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2219

Usefulness of Acute Pulmonary Vasoreativity Test to Inhaled No to Predict Efficacy of Pulmonary Vasodilators and Balloon Pulmonary Angioplasty in Patients With Inoperable CTEPH

Koichiro Sugimura, Tohoku Univ Graduate Sch of Med, Sendaisi, Japan; **Miku Sakota** , Tohoku Univ Graduate Sch of Med, Sendai, Miyagi, Japan; Shunsuke Tatebe, Tohoku Univ, Sendai, Japan; Shigefumi Fukui, Tohoku Univ Graduate Sch of Med, Sendai, Miyagi, Japan; Saori Yamamoto, Tohoku Univ Graduate Sch of Med, Sendai, Japan; Haruka Sato, Ryo Konno, Tohoku Univ, Sendai, Japan; Terui Yosuke, Tohoku Univ Graduate Sch of Med, Sendai, Miyagi, Japan; Kimio Satoh, Tohoku Univ, Sendai, Japan; Hiroaki Shimokawa, Tohoku Univ Grad Sch Med, Sendai City, Japan

1:30 PM

Board # 2220

Evaluating Risk Factors for Arrhythmogenesis in Pulmonary Hypertension

**Demi A Adedinsewo** , Rashid Alhusain, Amjad Saad, Jordan C Ray, Brian P Shapiro, Charles Burger, Fred Kusumoto, Mayo Clinic, Jacksonville, FL

1:30 PM

Board # 2221

Prognostic Value of Stroke Volume Index in Patients With Pulmonary Arterial Hypertension at Intermediate Risk

**Fabio Dardi** , Massimiliano Palazzini, Enrico Gotti, Elisa Zuffa, Alessandro De Lorenzis, Filippo Pasca, Daniele Guarino, Ilenia Magnani, Mariangela Rotunno, Andrea Rinaldi, Alessandra Manes, Nazzareno Galie, Inst of Cardiology, Univ of Bologna, Bologna, Italy

1:30 PM

Board # 2222

Pulmonary Arterial Elastance Independently Predicts Exercise Capacity and NYHA Functional Class in Pulmonary Arterial Hypertension

**Sthuthi David** , UVA Health System, Charlottesville, VA; Kenneth C Bilchick, Univ of Virginia HS, Charlottesvle, VA; Steve Noutong, Younghoon Kwon, Nishaki M Mehta, Univ of Virginia, Charlottesville, VA; Andrew Mihalek, UVA Health System, Charlottesville, VA; Mwenya Mubanga, Uppsala Univ, Uppsala, Sweden; Khadijah Breathett, Univ of Arizona, Tucson, AZ; Sula Mazimba, Univ of Virginia, Charlottesville, VA

1:30 PM

Board # 2224

Correlation of Biomarker ST2 and Right Ventricular Function by Echocardiography in Pediatric Pulmonary Arterial Hypertension

**Melanie Nies** , Johns Hopkins Univ, Baltimore, MD; Jun Yang, Johns Hopkins Hosp, Baltimore, MD; Megan Griffiths, Jie Zhu, Johns Hopkins Univ, Baltimore, MD; Stephanie Brandal, Johns Hopkins, Baltimore, MD; Eric D Austin, Vanderbilt Univ Medical Ctr, Nashville, TN; Pei-Ni Jone, Childrens Hosp Colorado, Aurora, CO; Dunbar D IVY, Univ of Colorado, Aurora, CO; Dhananjay Vaidya, Allen D Everett, Johns Hopkins Univ, Baltimore, MD

1:30 PM

Board # 2225

Right Ventricular Dysfunction Correlates With Impaired Angiogenesis in Non-ischemic Dilated Cardiomyopathy Patients

**Sabina Frljak** , Gregor Poglajen, Gregor Zemljic, Andraz Cerar, UMC Ljubljana, Ljubljana, Slovenia; Francois Haddad, Stanford Univ, Palo Alto, CA; Bojan Vrtovec, UMC Ljubljana, Ljubljana, Slovenia

1:30 PM

Board # 2226

Sex Based Differences in Outcomes Among Patients Undergoing Catheter Directed Therapy for Pulmonary Embolism

**Srilekha Sridhara** , Rishita Shah, Banner Univ Medical Ctr-Phoenix, Phoenix, AZ; Abhishek Sawant, Edward Distler, Univ of Arizona, Phoenix, AZ; Nidhi Kanwar, Ashish Pershad, Banner Univ Medical Ctr-Phoenix, Phoenix, AZ; Mehul Shah, Banner Desert Medical Ctr, Mesa, AZ

1:30 PM

Board # 2227

Contemporary Etiology, Prevalence and Outcome of Severe Right Ventricular Dysfunction

**Ratnasari Padang** , Nikhitha Chandrashekar, Manasawee Indrabhinduwat, Christopher Scott, Sushil Allen Luis, Krishnaswamy Chandrasekaran, Hector I Michelena, Vuyisile T Nkomo, Sorin Pislaru, Mayo Clinic, Rochester, MN; Patricia A Pellikka, Mayo Clinic Coll Med, Rochester, MN; Garvan Kane, Mayo Fndn, Rochester, MN

1:30 PM

Board # 2228

Elevated Interleukin 6 Levels Predict Greater Disease Severity and Survival in Adults With Pulmonary Arterial Hypertension

**Jenny Y Chen** , Catherine E Simpson, Rachel L Damico, Paul M Hassoun, Jun Yang, Melanie Nies, Megan Griffiths, Dhananjay Vaidya, Stephanie Brandal, Johns Hopkins Univ, Baltimore, MD; Michael W Pauciulo, Children's Hosp Medical Ctr Cincinnati, Cincinnati, OH; Eric D Austin, Vanderbilt Univ Medical Ctr, Nashville, TN; Dunbar D Ivy, Univ of Colorado, Aurora, CO; Bill Nichols, Children's Hosp Medical Ctr Cincinnati, Cincinnati, OH; Allen D Everett, Johns Hopkins Univ, Baltimore, MD

1:30 PM

Poster Professor

Jane A Leopold, Boston, MA

1:30 PM

Board # 2229

Mineralocorticoid Receptor Antagonists Prevent Further Decline in Cardiac Index and Improve Ventricular Interdependence in a Rat Model of Pulmonary Arterial Hypertension

**Mengyun Lu** , Adrien J Mazer, Natl Insts of Health Clinical Ctr, Bethesda, MD; Stasia A Anderson, Natl Heart, Lung, and Blood Inst, Bethesda, MD; Salina Gairhe, Li-Yuan Chen, Jasmine NH Nelson, Natl Insts of Health Clinical Ctr, Bethesda, MD; Audrey Noguchi, Zu-Xi Yu, Natl Heart, Lung, and Blood Inst, Bethesda, MD; Honghui Wang, Junfeng Sun, Robert L Danner, Natl Insts of Health Clinical Ctr, Bethesda, MD; Michael A Solomon, Natl Insts of Health, Bethesda, MD; Jason M Elinoff, Natl Insts of Health Clinical Ctr, Bethesda, MD

1:30 PM

Board # 2230

Prevalence and Outcomes Associated With Advanced Respiratory Support in Contemporary Cardiac Intensive Care Units: A Critical Care Cardiology Trials Network (CCCTN) Registry Study

**Thomas Stephen Metkus** , Johns Hopkins Univ Sch of Med, Luthvle Timon, MD; Khalil Ibrahim, Johns Hopkins Univ Sch of Med, Baltimore, MD; Jason N Katz, Univ of North Carolina, Chapel Hill, NC; Erin A Bohula, Brigham and Womens Hosp, Boston, MA; Jeong-Gun Park, Brigham and Women's Hosp, Boston, MA; Sean F van Diepen, Univ of Alberta, Edmonton, AB, Canada; Steven Paul Schulman, Johns Hopkins Medical Insts, Baltimore, MD; David A Morrow, Brigham and Women's Hosp, Boston, MA; CCCTN Investigators

# Abstract Poster Session

## HF.APS.03 - Assessing Prognosis in Heart Failure

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2065

Racial Differences in Utilization, Trends, and Prognostic Impact of Guideline-Directed Medical Therapy for HFrEF in the Community: The Atherosclerosis Risk in Communities (ARIC) Surveillance Study

**Lena Mathews** , Johns Hopkins Univ Sch of Med, Baltimore, MD; Ning Ding, Johns Hopkins Univ, Baltimore, MD; Laura R Loehr, Univ of North Carolina Chapel Hill, Chapel Hill, NC; Jung-im Shin, Johns Hopkins Univ, Baltimore, MD; Naresh M Punjabi, Johns Hopkins Univ Sch of Med, Baltimore, MD; Alain G Bertoni, Wake Forest Univ Sch of Med, Winston Salem, NC; Deidra C Crews, Johns Hopkins Univ Sch of Med, Baltimore, MD; Wayne D Rosamond, Univ of North Carolina Sch of Public Health, Chapel Hill, NC; Chiadi Ericson Ndumele, Johns Hopkins Univ Sch of Med, Baltimore, MD; Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD; Patricia Chang, Univ of North Carolina, Chapel Hill, NC

1:30 PM

Board # 2066

Prognostic Value of Admission Serum Uric Acid in Hospitalized Heart Failure Patients With Preserved Ejection Fraction: A Report From the Japanese Real-world Multicenter Registry

**Yuta Kobayashi** , Kazunori Omote, Toshiyuki Nagai, Kiwamu Kamiya, Tadao Aikawa, Takao Konishi, Takuma Sato, Hiroyuki Iwano, Shingo Tsujinaga, Yoshiya Kato, Hirokazu Komoriyama, Hokkaido Univ, Sapporo, Japan; Kazuhiro Yamamoto, Tottori Univ, Tottori, Japan; Tsutomu Yoshikawa, Sakakibara Heart Inst, Tokyo, Japan; Yoshihiko Saito, Nara Medical Univ, Nara, Japan; Toshihisa Anzai, Hokkaido Univ, sapporo, Japan

1:30 PM

Board # 2067

Prognostic Value of the Combination of Fibrosis-4 Index and the Get With the Guidelines-Heart Failure Risk Score in Patients Admitted for Acute Decompensated Heart Failure

**Masatsugu Kawahira** , Osaka General Medical Ctr, Oosaka, Japan; Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masahiro Seo, Osaka General Medical Ctr, Osaka City, Japan; Makoto Abe, Jun Nakamura, Kiyomi Kayama, Osaka General Medical Ctr, Osaka, Japan; Kazuya Tanabe, Osaka General Medical Ctr, Osaka, NY

1:30 PM

Board # 2068

Heart Failure Outcomes Among Veterans With Human Immunodeficiency Virus Infection

**Sebhat Erqou** , Lan Jiang, Michelle Lally, Providence VA Medical Ctr, Providence, RI

1:30 PM

Board # 2069

Validation of the Seattle Heart Failure Model in the Swedish Heart Failure Registry

**Sushan Yang** , Univ of Washington, Seattle, WA; Lars H Lund, Karolinska, Stockholm, Sweden; Song Li, Univ of Washington, Seattle, WA; Ulf Dahlstrom, Linkoping Univ, Linkoping, Sweden; Ulrik Sartipy, Karolinska Univ Hosp, Stockholm, Sweden; Wayne Levy, Univ Washington, Seattle, WA

1:30 PM

Board # 2070

Clinical and Echocardiographic Outcomes of Methamphetamine Abuse and Cessation in Heart Failure

**Harpreet Singh Bhatia** , Univ of California San Diego, San Diego, CA; Marin Nishimura, Univ of California San Diego, La Jolla, CA; Stephen Dickson, Univ of California San Diego, San Diego, CA; Eric D Adler, UCSD, La Jolla, CA; Barry H Greenberg, UCSD Sch Med, La Jolla, CA; Isac C Thomas, Univ of California-San Diego, La Jolla, CA

1:30 PM

Board # 2071

Prevalence and Prognostic Implications of Depression in Patients With Heart Failure With Preserved Ejection Fraction

**Neela D Thangada** , Vijay Agusala, Colby Ayers, Ambarish Pandey, UT Southwestern Medical Ctr, Dallas, TX

1:30 PM

Board # 2072

Comparison of Outcomes in Patients With Acute Exacerbation of Heart Failure With and Without Sepsis-In a Large Database Study

**Hassaan B Arshad** , Julius M Gardin, Rutgers New Jersey Medical Sch, Newark, NJ

1:30 PM

Board # 2073

Clinical Value of Neutrophil to Lymphocyte Ratio and Its Trajectory in Patients Hospitalized With Acute Heart Failure and Preserved Ejection Fraction

Kalyani Anil Boralkar, Stanford Univ Medical Ctr, Stanford, CA; Yukari Kobayashi, Myriam Amsallem, Stanford Univ, Palo Alto, CA; Jennifer Arthur Ataam, **Kegan James Moneghetti** , Stanford Univ, Stanford, CA; Benjamin D Horne, Intermountain Heart Institue, Salt Lake City, UT; Kirk Ute Knowlton, Intermountain Medical Ctr, Salt Lake City, UT; Holden T Maecker, Stanford Univ, Stanford, CA; Tatiana Kuznetsova, Univ of Leuven, Leuven, Belgium; Paul A Heidenreich, Palo Alto VA HCS, Palo Alto, CA; Francois A Haddad, Stanford Univ, Stanford, CA

1:30 PM

Board # 2074

Characteristics and Prognosis of Patients Hospitalized With Heart Failure With Mid-Range Ejection Fraction

**Cheng Chen** , Derek Phan, Rikin Tank, David Wee, Lewei Duan, Ming Sum Lee, Kaiser Permanente, Los Angeles, CA

1:30 PM

Poster Professor

Clyde W Yancy Jr., Chicago, IL

# Abstract Poster Session

## AT.APS.01 - Best of Basic Science Posters

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1000

A Reservoir of Fibroblasts Promotes Recovery From Limb Ischemia

**Shu Meng** , Jie Lu, Houston Methodist Res Inst, Houston, TX; Palas K Chanda, Methodist Res Inst, Houston, TX; Iris Owusu, Kaifu Chen, John P Cooke, Houston Methodist Res Inst, Houston, TX

1:30 PM

Board # 1001

Physiologic Oxygen Tension Enhances Proliferation, Resistance to Hypoxic Stress, Telomerase Activity and Telomere Length of Mouse Cardiac Mesenchymal Cells (CMCs)

Robi Bolli, Univ of Louisville, Louisville, KY; Dinesh Devadoss, Florida Intl Univ, Miami, FL; Chandrashekhar Dasari, Asma Arshia, Amr M Alkasir, Yibing Nong, Yiru Guo, Marcin Wysoczynski, **Qianhong Li** , Univ of Louisville, Louisville, KY

1:30 PM

Board # 1002

Calcium/calmodulin-dependent Protein Kinase II (CaMKII) Signaling in Cardiomyocytes Initiates Inflammasome Required for Adverse Cardiac Remodeling in Response to Pressure Overload

**Takeshi Suetomi** , Yamaguchi Univ, Ube, Japan; Andrew Willeford, Cameron Brand, Shigeki Miyamoto, Joan Heller Brown, Univ of California San Diego, La Jolla, CA

1:30 PM

Board # 1003

Genetic Determinants of the Development of the Human Sinoatrial Node

Michaela Asp, SciLifeLab Stockholm, Solna, Sweden; **Johan Christer Sylven** , Eva Wardell, Agneta Mansson-Broberg, KI, Stockholm, Sweden; Eugenio Cingolani, Cedars-Sinai, Smidt Heart Inst, Los Angeles, CA; Joakim Lundeberg, SciLifeLab Stockholm, Solna, Sweden

1:30 PM

Board # 1004

Exercise-Induced New Cardiomyocyte Formation in the Aged Mammalian Heart

Carolin Lerchenmüller, Massachusetts General Hosp, Boston, MA; Ana Vujic, Harvard Univ, Cambridge, MA; **Sonja Mittag** , Univ Hosp Heidelberg, Heidelberg, Germany; Annie Wang, Harvard Univ, Cambridge, MA; Charles Rabolli, Massachusetts General Hosp, Boston, MA; Frank Gyngard, Christelle Guillermier, Brigham and Women's Hosp, Cambridge, MA; Matthew L Steinhauser, Brigham and Womens Hosp, Boston, MA; Anthony Rosenzweig, MGH, Boston, MA; Richard T Lee, Harvard Univ, Cambridge, MA

1:30 PM

Board # 1005

Deficiency of Secreted and Transmembrane Protein 1a Aggravates Endotoxin-induced Inflammation and Myocardial Dysfunction

**Yutian Li** , Shan Deng, Xiaohong Wang, Wei Huang, Nathan Robbins, Xingjiang Mu, Kobina Essandoh, David Adams, Jack Rubinstein, Guo-Chang Fan, Univ of Cincinnati, Cincinnati, OH

1:30 PM

Board # 1006

Sequential Stimulation and Inhibition of Lysophosphatidic Acid Receptor 4 are Critical for Cardiac Differentiation and Repair

**Hyun-Jai Cho** , Choon-Soo Lee, Jin-Woo Lee, Hyo-Soo Kim, Seoul Natl Univ Hosp, Seoul, Korea, Republic of

1:30 PM

Board # 1008

Hepatic TRIB1 Regulates ApoB Metabolism by Modulating Its Production and Catabolism

**Katherine Quiroz-Figueroa** , Andrea M Berrido, Cecilia Vitali, Donna Conlon, John S Millar, Univ of Pennsylvania, Philadelphia, PA; Robert C Bauer, Columbia Univ, New York, NY; Nicholas J Hand, Daniel J Rader, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 1009

Sex as a Biological Variable is Evident Following Deletion of Intestinal Apolipoprotein A1

**Tara Price** , John Adams Jr., Johnathan Ballard, Huiping Guo, Andrei Golovko, Ben Morpurgo, Rosemary Walzem, Texas A&M Univ, College Station, TX

1:30 PM

Board # 1010

Pro-Inflammatory Small Low Density Lipoprotein-Like Particles in Patients With Severe Liver Disease

**Shimpi Bedi** , Univ of Cincinnati, Cincinnati, OH; Erwin Garcia, Elias Jeyarajah, LABCORP, Raleigh, NC; Irina Shalaurova, LabCorp, inc, Cary, NC; Maria Camila Perez-Matos, Harvard Medical Sch, Boston, MA; Esther Bullitt, Boston Univ Sch of Med, Boston, MA; Z. Gordon Jiang, Harvard Medical Sch, Boston, MA; James D Otvos, LABCORP, Morrisville, NC; Margery A Connelly, LABCORP, Raleigh, NC; Sean Davidson, Univ of Cincinnati, Cincinnati, OH

1:30 PM

Board # 1011

Pemafibrate, a Novel Selective Peroxisome Proliferator-Activated Receptor-A Modulator, Ameliorated Diabetes-Induced Endothelial Dysfunction

**Kumiko Sutou** , Tokushima Univ, Tokushima, Japan; Daiju Fukuda, Byambasuren Ganbaatar, Shusuke Yagi, Kenya Kusunose, Hirotsugu Yamada, Takeshi Soeki, Masataka Sata, Tokushima Univ Graduate Sch, Tokushima, Japan

1:30 PM

Board # 1012

A Screen Using Human Induced Pluripotent Stem Cell-Derived Hepatocytes to Identify Novel Drugs for the Treatment for Hypercholesterolemia

**Jui Tung Liu** , Mary P Lamprecht, Steven L Holshouser, Yuri K Peterson, Patrick M Woster, Stephen A Duncan, Medical Univ of South Carolina, Charleston, SC

1:30 PM

Board # 1013

The Ubiquitin-Like Protein Fat10 Attenuates Cardiac Hypertrophy by Promoting the Lysosomal Degradation of CaMK2D

**Yang Shen** , Wei Lai, Dandan Zhang, Rong Wan, Kui Hong, The Second Affiliated Hosp of Nanchang Univ, Nanchang, China

1:30 PM

Board # 1014

Aldehyde Dehydrogenase-2 Regulates the Mitochondrial Translocation of Dnmt1 in Cardiomyocyte

**Xiaolei Sun** , Yongchao Zhao, Shanghai Inst of Cardiovascular Diseases, Shanghai, China; Junbo Ge, Zhongshan Hosp Fudan Univ, Shanghai, China; Aijun Sun, Shanghai Inst of Cardiovascular Diseases, Shanghai, China

1:30 PM

Board # 1015

Mirna-mediated Suppression of a Cardioprotective Cardiokine as a Novel Mechanism Exacerbating Post-mi Remodeling by Sleep Breathing Disorders

**Yunhui Du** , Beijing Anzhen Hosp, Capital Medical Univ, Beijing, China; Linyi Li, Beijing Inst of Heart, Lung and Blood Vessel Diseases, Beijing; Huina Zhang, Beijing Anzhen Hosp, Capital Medical Univ, Beijing, China; Yanwen Qin, Beijing Inst of Heart, Lung and Blood Vessel Diseases, BEIJING, China; Yajing Wang, Wayne Bond Lau, Thomas Jefferson Univ, Philadelphia, PA; Yongxiang Wei, Beijing Anzhen Hosp, Capital Medical Univ, Beijing, China; Xinliang Ma, Thomas Jefferson Univ, Philadelphia, PA

1:30 PM

Board # 1016

Human Cardiomyocyte Protection From Apoptosis by Cardiac Progenitor Cell Secreted Factors

**Chrystalla Constantinou** , Imperial Coll London, London, United Kingdom; Michela Noseda, Imperial Coll London, London; Patricia Chaves, Antonio MA Miranda, Mohamed Bellahcene, Kevin Cheng, Sian Harding, Michael D Schneider, Imperial Coll London, London, United Kingdom

1:30 PM

Board # 1017

Examination of the Action Mechanism of Pemafibrate in a Novel Diet-induced Nonalcoholic Steatohepatitis Mouse Model

**Kotaro Kanno** , Dept of Cardiovascular Med, Osaka Univ Graduate Sch of Med, Suita-shi, Osaka-fu, Japan; Chang Jiuyang, Ayami Saga, Hiroyasu Inui, Takeshi Okada, Masumi Asaji, Yinghong Zhu, Makoto Nishida, Masahiro Koseki, Osaka Univ Sch of Med, Suita-shi, Osaka-fu, Japan; Shizuya Yamashita, Rinku General Medical Ctr, Izumisano-shi, Osaka-fu, Japan

1:30 PM

Board # 1018

**Deficiency of Phospholipase A** 2 **Receptor Exacerbates Autoimmune Myocarditis in Mice**

**Hiroki Kishi** , Univ of Yamanashi, Yamanashi, Japan; Yousuke Watanabe, Univ of Yamanashi, Chuo, Japan; Kazuhiro Watanabe, Univ of Yamanashi, Yamanashi, Japan; Daisuke Fujioka, Univ of Yamanashi, Chuo Yamanashi, Japan; Kazuto Nakamura, Univ of Yamanashi, tyuo, Japan; Ken-ichi Kawabata, Kiyotaka Kugiyama, Univ of Yamanashi, Chuo, Japan

1:30 PM

Board # 1019

Ultrasound-Targeted Microbubble Cavitation With Sodium Nitrite Synergistically Enhances Nitric Oxide Production and Microvascular Perfusion

**Gary Z Yu** , Filip Istvanic, Mehdi Nouraie, Xucai Chen, Univ of Pittsburgh, Pittsburgh, PA; John Pacella, Univ Pittsburgh, Pittsburgh, PA

1:30 PM

Board # 1020

New Cell Delivery System Cellsaic With Adipose-derived Stromal Cells Promotes Functional Angiogenesis for Critical Limb Ischemia in Mice

**Hideki Tanioka** , Osaka Univ, Suita Osaka, Japan; Shigeru Miyagawa, Daisuke Mori, Osaka Univ, Suita, Japan; Takuji Kawamura, Osaka Univ, Osaka, Japan; Takayoshi Ueno, Osaka Univ, Suita, Osaka, Japan; Koichi Toda, Osaka Univ, Kobe, Japan; Toru Kuratani, Osaka Univ / CV Surgery, Osaka, Japan; Yoshiki Sawa, Osaka Univ, Osaka, Japan

1:30 PM

Board # 1022

Hippo Pathway Effector TEAD1 Promotes Direct Cardiac Reprogramming

**Vivek P Singh** , Jaya Pratap Pinnamaneni, Aarthi Pugazenthi, Baylor Coll of Med, Houston, TX; Deepthi Sanagasetti, Baylor Coll of Med, Pearland, TX; Ayman Almousa, Megumi Mathison, Kai Wang, Abdussalam Elsenousi, Alexis E Shafii, Jianchang Yang, James F Martin, Todd K Rosengart, Baylor Coll of Med, Houston, TX

1:30 PM

Board # 1023

Atrial Fibrillation Disease Module on a Human Atrial Protein Interactome Reveals Novel Genes, Biological Pathways, and Drug Candidates

**Jun-Seop Song** , Yonsei Univ Coll of Med, Seoul, Korea, Republic of

1:30 PM

Board # 1025

**The Ca** v **3.2 Transient Type Calcium Channel Regulates Platelet Activation and Arterial Thrombosis**

**Hem K Tamang** , Inst of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

1:30 PM

Board # 1027

New Drug Repurposing Opportunities for Hypertension Uncovered by the Convergence of Genomics With Kidney Transcriptomics and Epigenomics

**Sushant Saluja** , Xiao Jiang, Inst of Cardiovascular Sciences, Manchester, United Kingdom; Chris Finan, Sandesh Chopade, Inst of Cardiovascular Sciences, London, United Kingdom; James Eales, Xiaoguang Xu, Inst of Cardiovascular Sciences, Manchester, United Kingdom; Nilesh J Samani, Glenfield Hosp, Leicester, United Kingdom; Fadi J Charchar, Univ DVE, Ballarat, Australia; Aroon Hingorani, Univ Coll London, London, United Kingdom; Maciej Tomaszewski, Manchester Univ, Manchester, United Kingdom

1:30 PM

Board # 1028

**Adipocyte-Specific Deletion of** Ager **Mice With Established Obesity Induces Weight Loss and Induces Adaptive Thermogenesis in Adipose Tissue**

**Lakshmi Arivazhagan** , Henry H Ruiz, NYU Langone Sch of Med, New York, NY; Jay Pendse, NYU Langone, New York, NY; Laura Frye, Kaamashri Mangar, NYU Langone Sch of Med, New York, NY; Ann Marie Schmidt, NYU Sch of Med, New York, NY

1:30 PM

Board # 1029

Dynamic Flow Activates Endothelial Notch Signaling to Promote Vascular Regeneration

**Kyung In Baek** , Mehrdad Roustaei, Chih-Chiang Chang, Shyr-Shea Chang, Yichen Ding, Marcus Roper, UCLA, Los Angeles, CA; Tzung K Hsiai, UCLA Sch of Med Cardiology Div, Los Angeles, CA

1:30 PM

Poster Professor

Masanori Aikawa, Boston, MA

# Abstract Poster Session

## HF.APS.04 - Beyond Ischemic Cardiomyopathy

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2085

N-Terminal Pro-B-Type Natriuretic Peptide Among Patients Living With Both HIV and Heart Failure

**Raza M. Alvi** , Markella V. Zanni, Anne M. Neilan, Malek Z.O. Hassan, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Noor Tariq, Yale New-Haven Hosp of Yale Univ Sch of Med, New Haven, CT; Lili Zhang, Dahlia Banerji, Connor P. Mulligan, Adam Rokicki, Magid Awadalla, James L. Januzzi, Tomas G. Neilan, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA

1:30 PM

Board # 2086

A Deep Learning Based Model for Predicting Heart Failure in Hypertrophic Cardiomyopathy Patients With Left Ventricular Outflow Tract Obstruction

**Ahmed S Fahmy** , BIDMC-Harvard Univ, Boston, MA

1:30 PM

Board # 2087

Sepsis Induced Cardiomyopathy Confers Higher Mortality in Patients With Septic Shock

**Balaram Krishna J Hanumanthu** , Isaac Laniado, Obiageli Offor Lynda, Jacobi Medical Ctr, AECOM, Bronx, NY; Ankit Kushwaha, Jacobi Medical Ctr/Albert Einstein Coll of Med, Bronx, NY; Anika Sasidharan Nair, Ankita Krishnan, Carla Rosenzvit, Adam Gershon, Jin Ei Chan, Simon Mendez-Bustamante, Jacobi Medical Ctr, AECOM, Bronx, NY; Perminder Gulani, Jacobi Medical Ctr, Bronx, NY

1:30 PM

Board # 2088

Papillary Muscle Realignment and Septal Myectomy for Obstructive Hypertrophic Cardiomyopathy: 1-Year Outcomes Experienced at a Single Center

**Lucy Q Lin** , Evan Shalen, Howard K Song, Stephen B Heitner, Oregon Health and Science Univ, Portland, OR

1:30 PM

Board # 2089

The Importance of Early Diagnosis in Peripartum Cardiomyopathy

**Jennifer Lewey** , Lisa Levine, Michal A Elovitz, Olga C Irizarry, Univ of Pennsylvania, Philadelphia, PA; Zoltan Arany, Univ Pennsylvania, Philadelphia, PA

1:30 PM

Board # 2090

A Comparison of Patients Hospitalized With Heart Failure and Cardiac Amyloidosis in The United States

**Rachel Volke** , Talal Alzahrani, George Washington Univ, Arlington, VA; Joseph Krepp, George Washington Univ, Washington, DC

1:30 PM

Board # 2091

Cardioprotective Effects of Beta Blockers in Duchenne Muscular Dystophy

**Satyabrata Das** , Forum Kamdar, Wuming Gong, Andre Klaassen Kamdar, Tatyana Meyers, Univ of Minnesota, Minneapolis, MN; Dewayne Townsend IV, Univ Minnesota, Minneapolis, MN; James M Ervasti, Univ of Minnesota, Minneapolis, MN; Timothy J Kamp, U of Wisconsin-Madison, Madison, WI; Joseph C Wu, Stanford Univ Sch of Med, Stanford, CA; Jianyi Zhang, Univ of Alabama at Birmingham, Birmingham, AL; Daniel J Garry, Lillehei Heart Inst - U of MN, Minneapolis, MN

1:30 PM

Board # 2092

Risk of Morbidity and Mortality in Takotsubo Cardiomyopathy With Right Ventricular Involvement - A Meta-analysis of Observational Trials

**Suchith Shetty** , Univ of Iowa, Iowa City, IA; Aaqib Malik, Westchester Medical Ctr, Valhall, NY; Kan Liu, Univ of Iowa, Iowa CIty, IA

1:30 PM

Board # 2093

Major Adverse Cardiac Events and the Timing and Dose of Corticosteroids in Immune Checkpoint Inhibitor-Associated Myocarditis

**Lili Zhang** , Daniel A Zlotoff, Masschusetts General Hosp, Boston, MA; Magid Awadalla, Massachusetts General Hosp, Boston, MA; Anju Nohria, Brigham and Women's Hosp, Boston, MA; Syed S Mahmood, Malek Hassan, Massachusetts General Hosp, Boston, MA; Franck Thuny, Aix-Marseille Univ, Marseille, France; Leyre Zubiri, Masschusetts General Hosp, Cambridge, MA; Sean Murphy, Massachusetts General Hosp, Boston, MA; Raza M Alvi, Massachusetts General Hosp, Quincy, MA; Adam Rokicki, Masschusetts General Hosp, Boston, MA; Connor Mulligan, Massachusetts General Hosp, Boston, MA; Maeve Jones-O'Connor, Masschusetts General Hosp, Boston, MA; Lucie Heinzerling, Univ Hosp Erlangen, Friedrich-Alexander-Univ Erlangen-Nürnberg (FAU), Erlangen, Germany; Ana Barac, MedStar Heart and Vascular Inst, Washington, DC; Brian Forrestal, Medstar Washington Hosp Cnter, Washington DC, DC; Eric H Yang, UCLA Medical Ctr, Culver City, CA; Carol L Chen, Memorial Sloan Kettering Cancer Ctr, Weill Cornell Medical Coll, New York, NY; Dipti Gupta, Memorial Sloan Kettering Cancer Cen, New York, NY; Michael C Kirchberger, Univ Hosp Erlangen, Friedrich-Alexander-Univ Erlangen-Nürnberg (FAU), Erlangen, Germany; Sachin Shah, Lahey Hosp and Medical Ctr, Burlington, MA; Otavio R Coelho-Filho, UNICAMP, Campinas, Brazil; Muhammad Rizvi, Lehigh Valley Health Network, Allentown, PA; Gagan Sahni, Mount Sinai Hosp, New York, NY; Anant Mandawat, Emory Univ, Atlanta, GA; Carlo G Tocchetti, Federico II Univ, Napoli, Italy; Valentina Mercurio, Federico II Univ, Naples, Italy; Michael Mahmoudi, Univ Hosp Southampton NHS, Southampton; Donald P Lawrence, Masschusetts General Hosp, Boston, MA; Sarju Ganatra, Lahey Hosp and Medical Ctr, Burlington, MA; Stephane Ederhy Sr., Hop Saint Antoine, Paris, France; John D Groarke, Brigham and Women's Hosp, Boston, MA; Alexander Lyon, Imperial Coll and Royal Brompton Hosp, London, United Kingdom; Paaladinesh Thavendiranathan, Univ of Toronto, Toronto, ON, Canada; Ryan J Sullivan, Masschusetts General Hosp, Boston, MA; Justine Cohen, Kerry Reynolds, Massachusetts General Hosp, Boston, MA; Michael George Fradley, Univ of South Florida, Tampa, FL; Tomas G Neilan, Massachusetts General Hosp, Boston, MA

1:30 PM

Board # 2094

Background and Complications in Patients With Takotsubo Cardiomyopathy (Insights From the National Inpatient Sample)

**Alberto Batarseh** , George Washington Univ, Washington, DC; Talal Alzahrani, George Washington Univ, Arlington, VA; Joseph Krepp, The George Washington Univ, Washington, DC

# Abstract Poster Session

## AC.APS.02 - Biomarkers II

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Andrew Paul DeFilippis, Louisville, KY

1:30 PM

Board # 4010

S100a12 as a Biomarker in Patients With Myocardial Infarction

**Cheng Hui Yan** , General Hosp of Northern Theater Command, Shenyang, China

1:30 PM

Board # 4021

Prognostic Implication of Elevated Troponin in Patients Visiting Emergency Department Without Diagnosis of Specific Cardiovascular Disease

**Minseok Song** , Samsung Medical Ctr, Seoul, Korea, Republic of; Jin-Ho Choi, Samsung Medical Ctr, Seoul; Taerim Kim, Jongen Park, Soohyun Park, Samsung Medical Ctr, Seoul, Korea, Republic of

1:30 PM

Board # 4012

Oxylipins and the Future Onset of Myocardial Infarction

**Chin-chou Huang** , Taipei Veterans General Hosp, Taipei, Taiwan; Meng-Ting Chang, Lie-Fen Shyur, Academia Sinica, Taipei, Taiwan; Jaw-Wen Chen, Taipei Veterans General Hosp, Taipei, Taiwan

1:30 PM

Board # 4014

Podocan a Novel Circulating Wnt-Pathway Inhibitor Predicts Major Adverse Cardiovascular Events in Patients With Coronary Artery Disease Independent of Framingham Cardiovascular Risk Factors in Synergy With Dickkopf-1

**Kanramon Watthanasuntorn** , Bishesh Shrestha, Nancy Bethuel, Bassett Medical Ctr, Cooperstown, NY; Charat Thongprayoon, Mayo Clinic, Rochester, MN; Kanjit Leungsuwan, Bassett Medical Ctr, Cooperstown, NY; Jennifer Victory, Bassett Res Inst, Cooperstown, NY; Paul Jenkins, Deborah Hyink, Daniel H Katz, Bassett Medical Ctr, Cooperstown, NY; Paul Klotman, Baylor college of medicine, Houston, TX; Jagdesh Kandala, 1501 N Campbell Avenue, Tucson, AZ; Randolph Hutter, Bassett Medical Ctr, Cooperstown, NY

1:30 PM

Board # 4015

The Association of White Blood Cell Count and Bleeding in Acute Coronary Syndrome: An Insight Into the Atlas ACS-TIMI 51 Trial

**Fahad Alkhalfan** , BIDMC, Boston, MA; Tarek Nafee, Harvard Medical Sch, Boston, MA; Megan Yee, Gerald C Chi, Arzu Kalayci, BIDMC, Boston, MA; Alexei Plotnikov, Johnson and Johnson, New Jersey, NY; Eugene Braunwald, Brigham and Women's Hosp, Boston, MA; C. Michael Gibson, BIDMC, Boston, MA

1:30 PM

Board # 4016

Temporal Changes of Biomarkers of Collagen Remodeling in Patients With Myocardial Infarction: The APACHE Cohort

**Signe Holm Nielsen** , Nordic Bioscience /Technical Univ of Denmark, Herlev, Denmark; Lena Jonasson, Faculty of Health Science, Linköping, Sweden; Magnus Janzon, Dept. of Cardiology, Linkoping, Sweden; Morten Karsdal, Nordic Bioscience, Herle, Denmark; Tomas Lindahl, Linköping Univ, Linköping, Sweden; Federica Genovese, Nordic Bioscience, Herlev, Denmark; Eva Elisabeth Swahn, Heart Ctr, Linkoping, Sweden; Joakim Alfredsson, Univtssjukhuset, Linkoping, Sweden

1:30 PM

Board # 4017

Classic Acute Myocardial Infarction Rule-Out Using Non-Ischemic 12-Lead Electrocardiography and Serial High-Sensitivity Cardiac Troponin Below the 99th Percentile: Safe and Efficient, and Simpler Than Other Approaches

**Yader Sandoval** , Mayo Clinic, Rochester, MN; Stephen Wallner Smith, Hennepin County Medical Ctr, Minneapolis, MN; Karen Schulz, Anne Sexter, Hennepin Health Res Inst, Minneapolis, MN; Fred S Apple, Hennepin County Medical Ctr, Minneapolis, MN

1:30 PM

Board # 4018

Urinary Liver-Type Fatty Acid-Binding Protein is More Useful Than Neutrophil Gelatinase-Associated Lipocalin for Predicting Acute Kidney Injury

**Hideto Nishimura** , Junnichi Ishii, Hiroshi Takahashi, Fumihiko Kitagawa, Hideki Kawai, Takashi Muramatsu, Masahide Harada, Akira Yamada, Fujita Health Univ, Toyoake, Japan; Mutsuharu Hayashi, Banbuntane Houtokukai Hosp, Nagoya, Japan; Sadako Tanizawa, Hiroyuki Naruse, Masayoshi Sarai, Eiichi Watanabe, Fujita Health Univ, Toyoake, Japan; Hideo Izawa, Banbuntane Houtokukai Hosp, Nagoya, Japan; Yukio Ozaki, Fujita Health Univ, Toyoake, Japan

1:30 PM

Board # 4019

Plasminogen Activator Inhibitor-1: A Genetic Marker for Coronary Atherosclerosis

Mohamed Gabr, Montefiore Medical Ctr, Bronx, NY; **Sarabjeet Suri** , AECOM- Montefiore Medical Ctr, Bronx, NY; Yelena Averbukh, Montefiore Medical Ctr, Bronx, NY

1:30 PM

Board # 4020

Dose-dependent Inhibitory Effect of Rosuvastatin in Japanese Patients With Acute Myocardial Infarction on Serum Concentration of Matrix Metalloproteinases - Invitation Trial -

**Koichiro Fujisue** , Kumamoto Univ, Kumamoto, Japan; Takuhiro Shirakawa, Fukuoka Tokushukai Medical Ctr, Kasuga, Japan; Shinichi Nakamura, Hitoyoshi Medical Ctr, Hitoyoshi, Japan; Nobuyasu Yamamoto, Miyazaki Prefectural Nobeoka Hosp, Nobeoka, Japan; Shuichi Oshima, Kumamoto Central Hosp, Kumamoto, Japan; Toshiyuki Matsumura, Japan Labor Health and Welfare Organization Kumamoto Rosai Hosp, Yatsushiro, Japan; Ryusuke Tsunoda, Kumamoto Red Cross Hosp, kumamoto, Japan; Nobutaka Hirai, Kumamoto Regional Medical Ctr, Kumamoto, Japan; Shinji Tayama, Kumamoto Univ, Kumamoto-City, Japan; Natsuki Nakamura, Shin-Beppu Hosp, Beppu, Japan; Toyoki Hirose, Minamata City General Hosp & Medical Ctr, Minamata, Japan; Kazuteru Fujimoto, Natl Hosp Organization Kumamoto Medical Ctr, Kumamoto, Japan; Hideki Shimomura, Fukuoka Tokushukai Medical Ctr, Kasuga, Japan; Yasuhiro Izumiya, Osaka City Univ, Osaka, Japan; Koichi Kaikita, Kumamoto Univ, Kumamoto, Japan; Hisao Ogawa, Natl Cerebral Cardiovascular Ctr, Suita Osaka, Japan; Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

# Abstract Poster Session

## CM.APS.02 - Body Composition, Cardiometabolic Risk and CVD Pathogenesis

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3010

Both Leanness and Obesity Were Associated With Cardiovascular Events in Patients With More Than 65 Years Old: The Japan Morning Surge Home Blood Pressure (J-HOP) Study

**Shinichi Toriumi** , Jichi Medical Univ, Shimotsuke Tochigi, Japan; Tomoyuki Kabutoya, Jichi Medical Univ, Shimotsuke Tochigi, Japan; Satoshi Hoshide, Jichi Medical Univ, Shimotsuke, Japan; Kazuomi Kario, Jichi Medical Univ, Tochigi-ken, Japan

1:30 PM

Board # 3011

Brown Adipocyte Adipokine Il18 Mediates Thermogenesis and Insulin Sensitivity Through Their Divergent Effects of Its Two Receptors

**Xian Zhang** , Songyuan Luo, Brigham and Women's Hosp, Boston, MA; Wang Minjie, Inner Mongolia Medical Univ, Hohhot, China; Zhiyong Deng, Guo-Ping Shi, Brigham and women's hospital, Boston, MA

1:30 PM

Board # 3012

Growth Differentiation Factor-15 (GDF-15) is Involved in Muscle Atrophy of Patients With Cardiovascular Diseases

**Toshiaki Nakajima** , Hironaga Ogawa, Tatsuya Sawaguchi, Syotarou Obi, Shibasaki Ikuko, Yuusuke Takei, Satoshi Sakuma, Shigeru Toyoda, Dokkyo Medical Univ, Tochigi, Japan; Masao Nishimura, Nishimura Heart Clinic, Ageoshi, Japan; Hirotsugu Fukuda, Teruo Inoue, Dokkyo Medical Univ, Tochigi, Japan

1:30 PM

Board # 3013

Waist Circumference is the Most Powerful Predictor of Maladaptive Left Ventricular Remodeling in Otherwise Healthy Adolescents

**Gurpreet Singh Johal** , Kristen Brown, Maribeth Johnson, Mathew Humphries, Bernard Gutin, Gaston Kapuku, Vincent JB Robinson, Augusta Univ, Augusta, GA

1:30 PM

Board # 3014

A Relative ANP Deficiency State With Increased Risk for Cardiometabolic Disease and Worse Outcomes in Male Gender: Rationale ForANP Hormonal Replacement Therapy

**Tomoko Ichiki** , Christopher G Scott, Valentina Cannone, Jeson Sangaralingham, Seethalakshmi R Iyer, Kent Bailey, Mayo Clinic, Rochester, MN; Jens Peter Goetze, Rigshospitalet, Copenhagen, Denmark; John C Burnett Jr, Mayo Clinic, Rochester, MN

1:30 PM

Board # 3015

An Obesity but Not Overweight Paradox After Coronary Artery Bypass Grafting Exists in Japanese Cohort

**Hiroki Hata** , Osaka Univ Graduate Sch of Med, Suita, Osaka, Japan; Koichi Toda, Osaka Univ Graduate Sch of Med, Suita, Japan; Shigeru Miyagawa, Osaka Univ, Suita, Japan; Yasushi Yoshikawa, Osaka Univ, Suita Osaka, Japan; Daisuke Yoshioka, Osaka Univ Hosp, Suita, Osaka, Japan; Satoshi Kainuma, Osaka university, Suita, Japan; Ai Kawamura, Osaka Univ, Suita-city, Osaka, Japan; Takuji Kawamura, Yoshiki Sawa, Osaka Univ, Osaka, Japan

1:30 PM

Board # 3016

Non-High Density Lipoprotein Cholesterol Association With Metabolic Syndrome in Obese Adolescents and Young Adults: Evaluation Using NHANES 2003-2014 Year-Cycles

**Carter William English** , Karen Sokal-Gutierrez, Univ of California - Berkeley, Berkeley, CA

1:30 PM

Board # 3017

Weight Loss in the Management of Overweight and Obese Patients With Atrial Fibrillation: A Systematic Review and Meta-analysis

**Omar M Aldaas** , Florentino Lupercio, Frederick T Han, Kurt S Hoffmayer, Univ of California San Diego, La Jolla, CA; David Krummen, Univ of California San Diego, San Diego, CA; Gordon Ho, Farshad Raissi, Ulrika Birgersdotter-Green, Gregory K Feld, Jonathan C Hsu, Univ of California San Diego, La Jolla, CA

1:30 PM

Board # 3018

The Modulating Effect of Exercise on Heart Rate Variability After Bariatric Surgery

**David Belzile** , Alexane Lebel, Audrey Auclair, Myriam Pettigrew, Laurent Biertho, Simon Marceau, Paul Poirier, IUCPQ, Québec, QC, Canada

1:30 PM

Board # 3019

Association of Short Term Changes in Waist Circumference and Weight With Long Term Cardiovascular Disease Events: The Heart Score Study

**Anum Saeed** , Heart and Vascular Insitute, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Justin Swanson, Univ of South Florida, Tampa, FL; Sebhat Erqou, VA Medical Ctr, Providence, RI; Ahmad Masri, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Kevin Kip, Univ of South Florida, Tampa, FL; Steven Reis, Univ Pittsburgh, Pittsburgh, PA

1:30 PM

Poster Professor

Tiffany M Powell-wiley, Silver Spring, MD

1:30 PM

Board # 3020

Increased Advanced Glycation End Products are a Risk Factor of Epicardial Adipose Tissue Thickness

**Shusuke Yagi** , Masataka Sata, Tokushima Univ Graduate Sch, Tokushima, Japan

1:30 PM

Board # 3021

Reduction of Cardiometabolic Risk in African Americans Utilizing the 2019 American College of Cardiology/American Heart Association Primary Prevention Nutrition Guidelines

**Kim Allan Williams Sr.** , Ibtihaj A M Fughhi, Sharon Gates, Stephen Sawyer, Setri Fugar, Hena Patel, Darrius Chambers, Rush Univ Medical Ctr, Chicago, IL; Ronald McDaniel, Boston Heart Diagnostics, Framingham, MA; Jochen R Reiser, Rush Univ Medical Ctr, Chicago, IL; Terry Mason, Cook County Dept of Public Health, Chicago, IL

1:30 PM

Board # 3022

Left Atrial Enlargement and Associated Cardiovascular Risk Factors in Obese Youth

**Edem Binka** , Johns Hopkins Hosp, Baltimore, MD; Tammy McLoughlin Brady, Johns Hopkins Univ, Baltimore, MD

# Abstract Poster Session

## ST.APS.01 - Cardioembolic Stroke

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2311

Dual Antiplatelet Therapy After Left Atrial Appendage Occlusion With the Watchman Device

**Erika Hutt** , Cleveland Clinic Fndn, Cleveland, OH; Simrat Kaur, Cleveland Clinic, Cleveland, OH; Jose Aguilera, Cleveland Clinic Fndn, Cleveland, OH; Walid I Saliba, Mohamed H Kanj, Khaldoun Tarakji, Cleveland Clinic, Cleveland, OH; Mouin S Abdallah, Cleveland Clinic, Cleveland, OH; Bryan Baranowski, Cleveland Clinic Fndn, Cleveland, OH; Daniel J Cantillon, Cleveland Clinic, Cleveland, OH; John Rickard, Cleveland Clinic, Cleveland Hts, OH; Thomas D Callahan IV, Cleveland Clinic, Cleveland, OH; Thomas J Dresing, Cleveland Clinic Fndn, Cleveland, OH; Mandeep Bhargava, Bruce D Lindsay, Cleveland Clinic, Cleveland, OH; Oussama Musbah Wazni, Ayman Hussein, Cleveland Clinic Fndn, Cleveland, OH

1:30 PM

Board # 2312

Effectiveness and Safety of Non-vitamin K Antagonist Oral Anticoagulants versus Warfarin Among Nonvalvular Atrial Fibrillation Patients With Polypharmacy Use

Gregory Y.H. Lip, Liverpool Ctr for Cardiovascular Science, Univ of Liverpool and Liverpool Heart & Chest Hosp, Liverpool, United Kingdom; Allison Keshishian, STATinMED Res and New York City Coll of Technology, Ann Arbor, MI; Amiee Kang, Amol Dhamane, Bristol-Myers Squibb Company, Lawrenceville, NJ; Xuemei Luo, Pfizer, Inc., Groton, CT; Christian Klem, Bristol-Myers Squibb Company, Lawrenceville, NJ; Lisa Rosenblatt, Bristol-Myers Squibb, Lawrenceville, NJ; Jack Mardekian, Pfizer, Inc., New York, NY; **Jenny Jiang** , Bristol-Myers Squibb Company, Lawrenceville, MI; Huseyin Yuce, New York City Coll of Technology, New York, NY; Steve Deitelzweig, Ochsner Clinic Fndn, New Orleans, LA

1:30 PM

Board # 2313

Real-World Evidence Studies Comparing Different Oral Anticoagulants in Patients With Non-Valvular Atrial Fibrillation: A Systematic Literature Review

**Steven Deitelzweig** , Ochsner Clinic Fndn, New Orleans, LA; Evelien Bergrath, Evidera, Waltham, MA; Manuela Di Fusco, Pfizer Inc., New York, NY; Amiee Kang, Bristol-Myers Squibb, Lawrence, NJ; Cristina Russ, Pfizer, New York, NY; Kassandra Snook, Allie Cichewicz, Lael Cragin, Evidera, Waltham, MA; Joseph Cappelleri, Pfizer, New York, NY; Kyle Fahrbach, Evidera, Waltham, MA

1:30 PM

Board # 2314

Novel Antithrombotic Effects of Dabigatran in Patients With NVAF

**Keisuke Tsuda** , Iwate Medical Univ, Morioka, Japan; Tatsunori Natori, Iwate Medical Univ, Iwate, Japan; Mie Shimizu, Iwate Medical Univ, Morioka, Japan; Kiyotaka Oi, Iwate Medical Univ, Iwate, Japan; Asami Kamada, Iwate Medical Univ, Morioka, Japan; Makiko Yoshida, Iwate Medical Univ, Morioka-shi, Japan; Shinsuke Narumi, Kazumasa Oura, Yoko Ishigaku, Yasuo Terayama, Tetsuya Maeda, Iwate Medical Univ, Morioka, Japan

1:30 PM

Board # 2315

Oral Anticoagulant for Atrial Fibrillation in Patients on Dialysis: Insights From a Network Meta-analysis

**Toshiki Kuno** , Mount Sinai Beth Israel, New York, NY; Hisato Takagi, Shizuoka Medical Ctr, Sizuoka, Japan; Tomo Ando, Detroit Medical Ctr,, Detroit, MI; Takehiro Sugiyama, NCGM, Tokyo, Japan; Satoshi Miyashita, Nelson Valentin, Mount Sinai Beth Israel, New York, NY; Yuichi J Shimada, Columbia Univ Medical Ctr, New York, NY; Masaki Kodaira, Japan Red Cross Ashikaga Hosp, Ashikaga, Japan; Yohei Numasawa, Japanese Red Cross Ashikaga Hosposs, Ashikaga, Japan; Alexandros Briasoulis, Univ of Iowa, Iowa City, IA; Alfred Burger, Mount Sinai Beth Israel, New York, NY; Sripal Bangalore, New York Univ Sch of Med, New York, NY

1:30 PM

Board # 2316

Valvular Heart Disease is Associated With Brain White Matter Changes in Patients With Neuropsychiatric Symptoms of Systemic Lupus Erythematosus

**Maka Gegenava** , Tea Gegenava, Thomas Huizinga, Leiden Univ Medical Ctr, Leiden, Netherlands

1:30 PM

Board # 2317

Left Atrial Appendage Dysfunction and Cerebrovascular Disease in Patients With Systemic Lupus Erythematosus

**Luisa Ciuffo Ciuffo** , Carlos Vazquez-Sosa, Michelle Ratliff, Richard Snider, Clifford R. Qualls, Univ of New Mexico, Albuquerque, NM; Carlos A Roldan, Univ of New Mexico Sch Med, Albuquerque, NM

1:30 PM

Board # 2318

Stroke Risk After Incidental Diagnosis of Papillary Fibroelastoma

**Kunal Jha** , Geisinger Medical Ctr, Danville, PA; Mamatha Pinninti, Vanderbilt Univ Medical Ctr, Nashville, TN; Erin Vanenkevort, Lokendra Thakur, Geisinger Medical Ctr, Danville, PA; Terry D Bauch, Geisinger Wyoming Valley Medical Ctr, Wilkes Barre, PA

# Abstract Poster Session

## HF.APS.02 - Care at the End-of-Life: Yes, We Can Still Help

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2056

Caregivers Experience With Difficult Decision Making in End-of-life Care of Patients Admitted for Cardiovascular Diseases

**Shinada Keitaro** , Keio Univ Sch of Med, Tokyo, Japan; Takashi Kohno, Kyorin Univ Sch of Med, Tokyo, Japan; Keiichi Fukuda, Keio Univ, Tokyo, Japan; Michiaki Higashitani, Tokyo Medical Univ Ibaraki Medical Ctr, Ibaraki, Japan; Naoto Kawamatsu, Mito Saiseikai General Hosp, Ibaraki, Japan; Takeshi Kitai, Kobe City Medical Ctr General Hosp, Hyogo, Japan; Tatsuhiro Shibata, Kurume Univ Sch of Med, Fukuoka, Japan; Makoto Takei, Tokyo Saiseikai Central Hosp, Tokyo, Japan; Kotaro Nochioka, Tohoku Univ Graduate Sch of Med, Miyagi, Japan; Gaku Nakazawa, Tokai Univ Sch of Med, Kanagawa, Japan; Hiroki Shiomi, Kyoto Univ Graduate Sch of Med, Kyoto, Japan; Mitsunori Miyashita, Tohoku Univ Graduate Sch of Med, Miyagi, Japan; Atsushi Mizuno, St. Luke's Intl Hosp, Tokyo, Japan

1:30 PM

Board # 2057

Feasibility of Palliative Sedation in Terminally Ill Heart Failure Patients at the End of Life

**Yasuhiro Hamatani** , Atsushi Hirayama, Eri Nakai, Michi Miyata, Emi Nakamura, Yukie Kawano, Yasuko Takada, Yuta Anchi, Michiyo Azechi, Sayaka Funabashi, Kyoko Hirakawa, Kensuke Kuroda, Natl Cerebral and Cardiovascular Ct, Osaka, Japan; Toshihisa Anzai, Hokkaido Univ, Sapporo, Japan; Chisato Izumi, Natl Cerebral and Cardiovascular Ct, Osaka, Japan

1:30 PM

Board # 2058

Development and Practical Test of Quality Indicators for Palliative Care in Heart Failure Patients

**Yasuhiro Hamatani** , Yasuko Takada, Yukie Kawano, Yuta Anchi, Michiyo Azechi, Atsushi Hirayama, Natl Cerebral and Cardiovascular Ct, Osaka, Japan; Tatsuhiro Shibata, Kurume Univ, Fukuoka, Japan; Atsushi Suzuki, Tokyo Women's Medical Univ, Tokyo, Japan; Mitsunori Nishikawa, Natl Ctr for Geriatrics and Gerontology, Aichi, Japan; Hiroto Ito, Natl Ctr of Neurology and Psychiatry, Tokyo, Japan; Masashi Kato, Natl Cancer Ctr, Tokyo, Japan; Tsuyoshi Shiga, Tokyo Women's Medical Univ, Tokyo, Japan; Yoshihiro Fukumoto, Kurume Univ, Fukuoka, Japan; Chisato Izumi, Satoshi Yasuda, Yasuo Sugano, Natl Cerebral and Cardiovascular Ct, Osaka, Japan; Toshihisa Anzai, Hokkaido Univ, Sapporo, Japan

1:30 PM

Board # 2059

Who Cares for the Caregiver? Heart Failure Caregiver Self-care

**Lucinda J Graven** , Flordia State Univ, Tallahassee, FL; Shamra Boel-Studt, Florida State Univ, Tallahassee, FL; Harleah G. Buck, Univ of South Florida, Tampa, FL; Laurie Abbott, Florida State Univ, Tallahassee, FL; Joan S Grant, Univ of Alabama at Birmingham, Hoover, AL

1:30 PM

Board # 2060

Preferences and Attitudes Toward Advance Care Planning and End-of-life Care of Patients Hospitalized for Heart Failure

Hiroki Kitakata, Keio Univ Sch of Med, Tokyo, Japan; **Takashi Kohno** , Kyorin Univ Sch of Med, Tokyo, Japan; Shun Kohsaka, Daisuke Fujisawa, Yasuyuki Shiraishi, Yoshinori Katsumata, Shinsuke Yuasa, Keiichi Fukuda, Keio Univ Sch of Med, Tokyo, Japan

1:30 PM

Board # 2061

Present Day Outcomes of Continuous Home Milrinone Infusion Therapy in Advanced Heart Failure With Reduced Ejection Fraction: A Single-Center Experience

**Pakpoom Tantrachoti** , Texas Tech Univ Health Sciences Ctr, Lubbock, TX; Wasawat Vutthikraivit, Texas Tech Health Sciences Ctr, Lubbock, TX; Pavida Pachariyanon, TTUHSC, Lubbock, TX; Sofia Prieto, Texas Tech Cardiology, Lubbock, TX; Nandini Nair, Texas Tech Univ HSC, Lubbock, TX

1:30 PM

Board # 2062

Predictors and Site-Level Variation in DNR Status Among Patients Hospitalized With Heart Failure

**Supriya Shore** , Donald Likosky, Univ of Michigan, Ann Arbor, MI; Edo Birati, Univ of Pennsylvania, Philadelphia, PA; Keith D Aaronson, Univ Michigan Medical Ctr, Ann Arbor, MI; Brahmajee K Nallamothu, Univ of Michigan, Ann Arbor, MI

1:30 PM

Board # 2063

Feasibility and Efficacy of Morphine Therapy for Refractory Dyspnea as Palliative Care in End-stage Chronic Heart Failure Patients

**Juri Kawaguchi** , Yasuhiro Hamatani, Atsushi Hirayama, Eri Nakai, Emi Nakamura, Michi Miyata, Yukie Kawano, Yasuko Takada, Yuta Anchi, Sayaka Funabashi, Kensuke Kuroda, Michiyo Azechi, Hiroyuki Takahama, Natl Cerebral and Cardiovascular Ctr, Osaka, Japan; Hiroaki Kitaoka, Kochi Medical Sch Hosp, Kochi, Japan; Chisato Izumi, Natl Cerebral and Cardiovacular Ctr, Osaka, Japan

1:30 PM

Board # 2064

Retrospective Case Series of Elective LVAD Deactivation Prior to Death

**Sabin Parajuli** , Hunter Groninger, Tara Coles, Medstar Washington Hosp Ctr, Washington, DC, DC

1:30 PM

Poster Professor

Sarah Goodlin, Portland, OR

# Abstract Poster Session

## SI.APS.01 - Cell and Tissue Engineering

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1170

Upregulation of Sug1 in Transplanted Allogeneic Mesenchymal Stem Cells Leads to Poor Survival of Implanted Cells in the Ischemic Heart

Ejlal Abu-El-Rub, St. Boniface Gen Hosp Res Cen, Winnipeg, MB, Canada; Niketa Sareen, Glen Lester Sequiera, Inst of Cardiovascular Science, Winnipeg, MB, Canada; Weiang Yan, **Sanjiv Dhingra** , St. Boniface Gen Hosp Res Cen, Winnipeg, MB, Canada

1:30 PM

Board # 1171

Exosomal microRNA 486-5p Mediates Cardiac Angiogenesis Post Myocardial Infarction by Targeting MMP19 in Fibroblasts

**Xinyang Hu** , Qingju Li, Yinchuan Xu, Jian'an Wang, Zhejiang Univ, Hangzhou, China

1:30 PM

Board # 1172

**Transendocardial CD34** + **Cell Therapy Improves Local Mechanical Dyssynchrony in Patients With Non-ischemic Dilated Cardiomyopathy**

**Gregor Poglajen** , Neža Žorž, Sabina Frljak, Bojan Vrtovec, UMC Ljubljana, Ljubljana, Slovenia

1:30 PM

Board # 1173

Effective and Functional Somatic Gene Transfer of mRNAs Into the Myocardium

**David Wolfson** , Emory Univ, Atlanta, GA; Jared Beyersdorf, Georgia Tech, Atlanta, GA; Nam Kyun Kim, Michael Sayegh, Emory Univ, Atlanta, GA; Philip Santangelo, Georgia Tech, Atlanta, GA; Hee Cheol Cho, Emory Univ, Atlanta, GA

1:30 PM

Board # 1174

Tbx18 Activates Proliferation of Non-Myocytes and Fibrotic Response via Tgfβ Signaling

**Jinqi Fan** , Natasha Fernandez, Heecheol Cho, Emory Univ, Atlanta, GA

1:30 PM

Board # 1175

Magnetically-actuated Alginate Scaffold Enhances Infiltration of Classically Activated Host-macrophages

**Lindsay Steele** , Drexel Univ Coll of Med, Philadelphia, PA; Kara Spiller, Drexel Univ, Philadelphia, PA; Smadar Cohen, Ben-Gurion Univ of the Negev, Beer-Sheva, Israel; Boris Polyak, Drexel Univ Coll of Med, Philadelphia, PA

1:30 PM

Board # 1176

Notch Signaling Modified Mesenchymal Stem Cell-sheet Transplantation Induce Left Ventricular Reverse Remodeling by Enhancing Cytokine Paracrine Effects in a Rat Ischemic Cardiomyopathy Model

**Shusaku Maeda** , Shigeru Miyagawa, Osaka Univ, Suita, Japan; Takuji Kawamura, Akima Harada, Osaka Univ, Osaka, Japan; Dai Chida, Sanbio, Tokyo, Japan; Takayoshi Ueno, Koichi Toda, Osaka Univ, Suita, Japan; Yoshiki Sawa, Osaka Univ, Osaka, Japan

1:30 PM

Board # 1177

Repopulated Pediatric-sized Decellularized Heart: A Tool For Ex Vivo Tests

Camila Hochman-Mendez, Fernanda Mesquita, Joern Huelsmann, Karis R Tang-Quan, Ernesto Curty da Costa, Po-Feng Lee, Luiz Sampaio, **Doris A Taylor** , Texas Heart Inst, Houston, TX

1:30 PM

Board # 1178

Decellularized Arterial Extracellular Matrix-Based Hydrogel Supports 3D Bioprinting of the Media Layer of Small-Caliber Blood Vessels

**Gabriel R Liguori** , Viktor Sinkunas, TissueLabs Pesquisa e Desenvolvimento LTDA, Sao Paulo, Brazil; Tácia Ta Liguori, Heart Inst (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, Univ de Sao Paulo, Sao Paulo, Brazil; Emerson G Moretto, TissueLabs Pesquisa e Desenvolvimento LTDA, Sao Paulo, Brazil; Prashant K Sharma, Martin C Harmsen, Univ of Groningen, Univ Medical Ctr Groningen, Groningen, Netherlands; Luiz Felipe P Moreira, Heart Inst (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, Univ de Sao Paulo, Sao Paulo, Brazil

1:30 PM

Board # 1179

Evaluations for Patency and Recellularization of Decellularized Vascular Grafts With High Hydrostatic Pressure Method in a Xeno-Implantation Animal Model

**Shunji Kurokawa** , Hidetoshi Masumoto, Graduate Sch of Med, Kyoto Univ, Kyoto, Japan; Yoshihide Hashimoto, Inst of Biomaterials and Bioengineering, Tokyo Medical and Dental Univ, Tokyo, Japan; Seiichi Funamoto, Osaka Inst of Technology, Osaka, Japan; Tadashi Ikeda, Graduate Sch of Med, Kyoto Univ, Kyoto, Japan; Akio Kishida, Inst of Biomaterials and Bioengineering, Tokyo Medical and Dental Univ, Tokyo, Japan; Kenji Minatoya, Graduate Sch of Med, Kyoto Univ, Kyoto, Japan

1:30 PM

Poster Professor

Muralidhar Padala, Atlanta, GA

1:30 PM

Board # 1180

Cell Cycle Activating Chemicals Enhance the Regenerative Potency of Human Cardiac Muscle Patch in Myocardial Infarction Mice

**Chengming Fan** , Yawen Tang, Univ of Alabama at Birmingham, birmingham, AL; Meng Zhao, Univ of Alabama at Birmingham, Birmingham, AL; Jinfu Yang, The Second Xiangya Hosp, Central South Univ, Changsha, China; Philippe Menasche, Univ Sorbonne Paris Cité, Paris, France; Wuqiang Zhu, Jianyi Zhang, Univ of Alabama at Birmingham, Birmingham, AL

# Abstract Poster Session

## WS.APS.01 - CHD in Women

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Annabelle Santos Volgman, Chicago, IL

1:30 PM

Board # 3103

Impact of Transitioning to High Sensitivity Troponin on the Evaluation of Chest Pain in Women

Sean Dikdan, **Timothy Colangelo** , Alexandra Ward, Joey Junarta, Brian Elliot, Andria Jones, Thomas Jefferson Univ, Philadelphia, PA

1:30 PM

Board # 3104

Symptom Presentation in Women With Ischemia and Non-Obstructive Coronary Artery Disease (INOCA): Are Their Symptoms Truly Atypical?

Yasmeen Taha, **Ahmad Mahmoud** , Qian Li, Ruxandra I. Sava, R David Anderson, Eileen M Handberg, Univ of Florida, Gainesville, FL; C. Noel Bairey Merz, Cedars-Sinai Medical Ctr, Los Angeles, CA; Carl J. Pepine, Univ of Florida, Gainesville, FL

1:30 PM

Board # 3105

Long-Term Outcomes Following Fractional Flow Reserve Guided Percutaneous Coronary Intervention in Women With Stable Coronary Artery Disease

**Sonia Shah** , Stanford Univ, Palo Alto, CA; Takeshi Nishi, Yuhei Kobayashi, William F Fearon, Stanford Univ, Stanford, CA

1:30 PM

Board # 3106

Coronary Artery Disease in Premenopausal Women: Looking at and Beyond the Sex Hormones

Ankit Sahu, Sanjay Gandhi Post Graduate Inst of Medical Sciences, Lucknow, India; Danish Kazmi, Assistant Professor of Med, Era Medical Coll and Hosp, Lucknow, Lucknow, India; **Paurush Ambesh** , Univ of Massachusetts Medical Sch-Baystate, Springfield, MA; Goel Pravin, Professor, Sanjay Gandhi Post Graduate Inst of Medical Sciences, Lucknow, India

1:30 PM

Board # 3107

The Associations of Psychosocial Stressors and Coronary Heart Disease

**Conglong Wang** , Félice Lê-Scherban, Jennifer Taylor, Drexel Univ, Philadelphia, PA; Elena Salmoirago-blotcher, Miriam Hosp, Brown Med Sch, Providence, RI; Matthew A Allison, Univ of California San Diego, La Jolla, CA; Gefen David, Lucy Robinson, Yvonne Michael, Drexel Univ, Philadelphia, PA

1:30 PM

Board # 3108

Platelet-Monocyte Aggregates Correlate With Psychological Stress and Are Increased in Women With Myocardial Infarction With Non-Obstructive Coronary Artery Disease (MINOCA): Findings From the American Heart Association Go Red for Women Strategically Focused Research Network

**Angela H Lee** , New York Univ Sch Med, New York, NY; Tessa Barrett, Tanya M Spruill, NYU Sch of Med, New York, NY; Harmony Reynolds, NYU Sch Med, New York, NY; Judith S Hochman, NYU Sch of Med, New York, NY; Jeffrey S Berger, New York Univ Sch Med, New York, NY; on behalf of the Sarah Ross Soter Center for Women's Cardiovascular Research at NYU

1:30 PM

Board # 3109

Stress Hormone Inhibition of Estrogen Transcriptional Regulation of the Serotonin Receptor 2b in the Heart Exacerbates Cardiomyocyte Apoptosis in Ischemia Reperfusion Injury

Natalie Carroll, Shripa Amatya, Lilly Kamberov, Wayne Anthony Orr, LSU Health Science Ctr, Shreveport, LA; John Anthony Cidlowski, Natl Institues of Heath, RTP, NC; **Diana Cruz-Topete** , LSU Health Science Ctr, Shreveport, LA

1:30 PM

Board # 3110

Psychological and Demographic Correlates of Objectively Measured Sleep Duration and Quality in Women With Myocardial Infarction

**Chorong Park** , Zoe Duberstein, Mallory Rutigliano, Jolaade Kalinowski, Judite Blanc, Amanda J Shallcross, NYU Sch of Med, New York, NY; Ki Park, Univ of Florida, Gainesville, FL; Catalin Toma, UPMC, Pittsburgh, PA; Nissi Suppogu, Cedars Sinai, Los Angeles, CA; Laxmi S Mehta, Ohio State Univ, Powell, OH; Khalil Ibrahim, Johns Hopkins Sch of Med, Baltimore, MD; Kevin Marzo, NYU Winthrop Hosp, Mineola, NY; Nisha Jhalani, Columbia Medical Ctr, New York, NY; Dwithiya Thomas, St. Lukes Univ Health Network, Bethlehem, PA; Caitlin M Giesler, Seton Heart Inst, Austin, TX; Bina Ahmed, Dartmouth Hitchcock, Lebanon, NH; Puja K Mehta, Emory Univ, Atlanta, GA; Harmony Reynolds, Tanya M Spruill, NYU Sch of Med, New York, NY

1:30 PM

Board # 3111

Gender Differences in Bone Marrow microRNA Expression in Patients With Ischemic Cardiovascular Disease

Lourdes Chacon, Ernesto Curty da Costa, Shundar Ahad, Hassan Virk, Luiz Sampaio, **Doris A Taylor** , Texas Heart Inst, Houston, TX

1:30 PM

Board # 3112

Gender Differences in the Risk Factors Associated With Atherosclerosis Evaluated by Carotid Intima-Media Thickness, Plaque Score and Pulse Wave Velocity

**Satoko Ojima** , Takuro Kubozono, Shin Kawasoe, Takeko Kawabata, Masaaki Miyata, Graduate Sch of Medical and Dental Sciences, Kagoshima Univ, Kagoshima, Japan; Hironori Miyahara, Kagoshima Kouseiren, Kagoshima, Japan; Shigeho Maenohara, Kagoshima Kouseiren, Kagohima, Japan; Mitsuru Ohishi, Graduate Sch of Medical and Dental Sciences, Kagoshima Univ, Kagohima, Japan

# Abstract Poster Session

## AC.APS.01 - Chronic Ischemic Heart Disease

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4009

Role of Monocytes in the Treatment of Vascular Calcifications: Involvement of the Calcium-Sensing Receptor (CaSR)

**Thibaut Objois** , Alice Sejourne, Michel Brazier, Cedric Boudot, Said Kamel, Isabelle Six, Romuald Mentaverri, Lab MP3CV, Amiens, France

1:30 PM

Board # 4000

The Association Between Temporary Decrease of Renal Function During Hospitalization and Mortality Risk in Patients After Myocardial Infarction

**Otto Mayer** , Charles Univ, Medical Faculty, Plzen, Czech Republic; Jan Bruthans, Thomayers Hosp, Prague, Czech Republic

1:30 PM

Board # 4001

Serum Soluble Klotho As A Novel Biomarker For Coronary Artery Calcification Of Culprit Lesions In Patients With Stable Angina Pectoris

**Seiji Koga** , Nagasaki Univ Hosp, Nagasaki, Japan; Satoshi Ikeda, Nagasaki Univ Grad Schl Biomed Sci, Nagasaki, Japan; Rhohei Akashi, Nagasaki Univ Hosp, Nagasaki, Japan; Yuki Yamagata, Nagasaki Univ Graduation Sch of Biomedical Sciences, Nagasaki, Japan; Tsuyoshi Yonekura, Nagasaki Univ Hosp, Nagasaki, Japan; Hiroaki Kawano, Nagasaki Univ, Nagasaki, Japan; Koji Maemura, Nagasaki Univ Hosp, Nagasaki, Japan

1:30 PM

Board # 4008

Cardiac Troponin T and N-terminal Pro-B-type Natriuretic Peptide for Detection of Myocardial Ischemia Among Patients With Suspected Stable Angina

**Peder L Myhre** , Akershus Univ Hosptial, Oslo, Norway; Helge Rosjo, Akershus Univ Hosp, Lorenskog, Norway; Sebastian Imre Sarvari, Oslo Univ Hosp Rikshospi, Oslo, Norway; Heikki Juhani Ukkonen, Turku Univ Central Hosp, Turku, Finland; Frank EMA Rademakers, Univ Hosp Leuven, Leuven, Belgium; Jan E. Engvall, Linkoping Univ Hosp, Linkoping, Sweden; Tor-Arne Hagve, Akershus Univ Hosptial, Oslo, Norway; Eike C Nagel, Goethe Univ Frankfurt, Frankfurt; Rosa Sicari, Inst of Clinical Physiology, Pisa, Italy; Jose Zamorano, Hosp Ramon y Cajal, Madrid; Mark J Monaghan, Kings Coll Hosp, London, United Kingdom; Jan d'Hooge, Univ of Leuven, Leuven, Belgium; Thor Edvardsen, Oslo Univ Hosp Rikshospi, Oslo, Norway; Torbjoern Omland, Akershus Univ Hosp, Lorenskog, Norway

1:30 PM

Board # 4004

Enhanced External Counterpulsation Added to Ranolazine Improves Markers of Functional Capacity

Sanaz Ziad, Univ of the Pacific, Stockton, CA; Jamil Malik, South Texas Cardiovascular Consultants, San Antonio, TX; Obinna Isiguzo, Methodist Texas Heart Hosp., San Antonio, TX; Lang Xu, Leqi Chen, Legacy Heart Care, Fort Worth, TX; Annette Cox, Univ of the Pacific, Fort Worth, TX; **Sachin A Shah** , Univ of the Pacific, Vacaville, CA

1:30 PM

Board # 4003

Repeat Coronary Reactivity Testing in Women With Ischemia and No Obstructive Coronary Artery Disease

**Nissi Suppogu** , Barbara Streisand Womens Heart Ctr, Cedars Sinai, Los Angeles, CA; Janet Wei, Cedars-Sinai Medical Ctr, Los Angeles, CA; Jenna Maughan, Sandy Joung, Barbara Streisand Womens Heart Ctr, Cedars Sinai, LA, CA; Odayme Quesada, Cedar Sinai Medical Ctr, Los Angeles, CA; Chrisandra Shufelt, Cedars-Sinai Medical Ctr, Los Angeles, CA; Bruce Samuels, Cedars Sinai Medical Ctr, LA, CA; Babak Azarbal, Cedars-Sinai Heart Inst, Beverly Hills, CA; Noel Bairey-Merz, Barbara Streisand Womens heart center, Cedars Sinai, Los Angeles, CA

1:30 PM

Board # 4006

Importance of the Medical Interview: Are Prolonged Chest Symptoms the Index for Vasospastic Angina With a Higher Activity?

**Hiroki Teragawa** , Chikage Oshita, Yuichi Orita, JR Hiroshima Hosp, Hiroshima, Japan; Yasuki Kihara, Hiroshima Univ Hosp, Hiroshima, Japan

1:30 PM

Board # 4005

Atherosclerotic Cardiovascular Risk Score as a Predictor of Coronary Artery Disease Burden in Stable Chest Pain

**Marissa K Edmiston** , Jaclyn R Rivington, Case Western Reserve (Metrohealth), Cleveland, OH; Sunil Krishna Vasireddi, MetroHealth Medical Ctr, Cleveland, OH; Meera Kondapaneni, Case Western Reserve (Metrohealth), Cleveland, OH

1:30 PM

Board # 4002

Hyperuricemia is Associated With Target Vessel Revascularization After Percutaneous Coronary Intervention for Chronic Total Occlusion

**Yoshiyuki Okuya** , Tokushima Red Cross Hosp, Komatsushima, Japan; Yuichi Saito, Yale Univ Sch of Med, New Haven, CT; Takefumi Takahashi, Koichi Kishi, Tokushima Red Cross Hosp, Komatsushima, Japan

# Abstract Poster Session

## CH.APS.05 - Congenital Heart Surgery II

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4078

Trisomy 21 is Associated With Longer Postoperative Length of Stay and Increased Rate of Postoperative Gastrostomy After Complete Repair of Tetralogy of Fallot

**Eric T Purifoy** , Beverly Spray, Joe Riley, Parthak Prodhan, Elijah H Bolin, ACRI-UAMS, Little Rock, AR

1:30 PM

Board # 4079

Impact of Cardiac Intervention on Long-term Survival and Home Discharge in Trisomy 18 Patients: A Propensity Score-matched Analysis

**Kenichi Okamura** , Japanese Red Cross Medical Ctr, Shibuya-ku Tokyo, Japan; Toshihiko Suzuki, Japanese Red Cross Hosp, Tokyo, Japan; Tao Fujioka, Atsushi Nakao, Keiji Tsuchiya, Japanese Red Cross Medical Ctr, Shibuya-ku Tokyo, Japan; Jotaro Kobayashi, Japanese Red Cross Medical Ctr, Tokyo, Japan

1:30 PM

Board # 4080

Early Pulmonary Artery Banding Improves the Long-term Survival in Trisomy 18 Infants: A Receiver Operating Characteristic Curve Analysis

**Kenichi Okamura** , Japanese Red Cross Medical Ctr, Shibuya-ku Tokyo, Japan; Toshihiko Suzuki, Japanese Red Cross Hosp, TOKYO, Japan; Tao Fujioka, Atsushi Nakao, Keiji Tsuchiya, Japanese Red Cross Medical Ctr, Shibuya-ku Tokyo, Japan; Jotaro Kobayashi, Japanese Red Cross Medical Ctr, Tokyo, Japan

1:30 PM

Board # 4081

Predictors and Clinical Significance of Failed Extubation in Neonates After Cardiac Surgery

**Hunter C Wilson** , Ray Lowery, Gabe Owens, Stephanie A Goldstein, Megan Gunsaulus, Sunkyung Yu, Mary K Olive, Univ of Michigan, Ann Arbor, MI

1:30 PM

Board # 4083

Surgical Outcome of Artificial Chords for Mitral Valve Repair in Children

**Shuhua Luo** , Lynne E Nield, Maruti Haranal, Mimi Deng, Jaymie Varenbut, The Hosp for Sick Children, Toronto, ON, Canada; Christoph Haller, Univ of Toronto, Toronto, ON, Canada; Osami Honjo, Hosp for Sick Children, Toronto, ON, Canada

1:30 PM

Board # 4084

Endocardial Fibroelastosis is Associated With Morbidity and Mortality in Patients With Small Left Heart Structures Undergoing Biventricular Conversion

**Meaghan J. Beattie** , Lynn A Sleeper, Minmin Lu, Sarah Teele, Sitaram Emani, Roger E Breitbart, Jesse Esch, Joshua Salvin, Urvi Kapoor, Olubunmi Oladunjoye, Puja Banka, Boston Children's Hosp, Boston, MA

1:30 PM

Board # 4085

Ross Autograft Leaflet Response to Systemic Circulation: Expression Profiling Reveals Divergence From Normal Aortic and Pulmonary Valve Leaflets

**Katsuhide Maeda** , Xiaoyuan Ma, Ariana Goodman, Christina Greene, Frank Louis Hanley, Robert K Riemer, Stanford Univ, Stanford, CA

1:30 PM

Board # 4086

Outcomes in Anomalous Aortic Origin of a Coronary Artery Following Surgical Reimplantation in a Prospective Cohort

**Carlos Bonilla-Ramirez** , Binsalamah Ziyad, Prakash Masand, Shagun Sachdeva, Dana Reaves-O'Neal, Texas Children's Hosp, Houston, TX; Christopher Caldarone, Texas Childrens Hosp, Houston, TX; Silvana M Molossi, BCM Texas Children's Hosp, Houston, TX

1:30 PM

Board # 4087

Ratio of Invasive to Non-Invasive Ventilation Relative to Achieving Full Enteral Nutrition in Neonates Following Congenital Heart Surgery

**Michelle Rybka** , UCSF, San Francisco, CA; Shabnam Peyvandi, Univ California San Fran, San Francisco, CA; Martina Andrea Steurer, UCSF Dept of Pediatrics, San Francisco, CA; Julianne Miller, UCSF, San Francisco, CA; Sarah Tabbutt, UCSF Benioff Childrens Hosp, Mill Valley, CA

1:30 PM

Poster Professor

James W Gaynor, Philadelphia, PA

1:30 PM

Board # 4088

Risk Factors for Adverse Outcomes After a Glenn Procedure in Patients With a Single Ventricle

**Gurpreet Khaira** , Venkatesan Ben Sivarajan, Gonzalo Guerra, Ari Joffe, Charlene MT Robertson, Gwen Y Bond, Stollery Children's Hosp, Edmonton, AB, Canada

1:30 PM

Board # 4089

Serum Metabolites as Biomarkers for Acute Kidney Injury in Neonates With Congenital Heart Disease Post-Cardiopulmonary Bypass

**Jessica J Heibel** , Johns Hopkins SOM, Baltimore, MD; Allen D Everett, Johns Hopkins, Glenwood, MD; David Graham, Johns Hopkins SOM, Baltimore, MD; Eric M Graham, Medical Univ of South Carolin, Charleston, SC

# Abstract Poster Session

## EP.APS.03 - Depression and Psychosocial Influences on CVD

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Nour Makarem, New York, NY

1:30 PM

Board # 3053

Acute Psychological Stress, Autonomic Function, And Arterial Stiffness Among Women

**Xiaoyue Liu** , Univ of Virginia, Charlottesvle, VA; Soojung Ahn, Univ of Virginia SON, Charlottesville, VA; Jeongok Gang Logan, Univ of Virginia, Charlottesvle, VA

1:30 PM

Board # 3054

Depressive Symptoms, Cardiac Function, and Risk of Heart Failure With Preserved or Reduced Ejection Fraction in Late Life: The Atherosclerosis Risk in Communities (ARIC) Study

**Katja Vu** , Brigham and Women's Hosp, Boston, MA; Janice E Williams, Univ of North Carolina at Chapel Hill, Chapel Hill, NC; Brian Claggett, Brigham and Women's Hosp, Boston, MA; Jenine E John, Brigham and Women's Hosp, Nanuet, NY; Hicham Skali, Scott D Solomon, Brigham and Women's Hosp, Boston, MA; Thomas Mosley, Univ of Mississippi Medical Ctr, Jackson, MS; Anna Kucharska-Newton, Univ of North Carolina, Chapel Hill, NC; Tor Biering-Soerensen, Herlev and Gentofte Hosp, Copenhagen, Denmark; Amil M Shah, Brigham and Women's Hosp, Boston, MA

1:30 PM

Board # 3055

Depression and Non Fatal Cardiovascular Diseases Among Adults in the United States

**Yosef Khan** , American Heart Association, Dallas, TX; Remy Poudel, American Heart Association, Irving, TX; Kim Stitzel, American Heart Association, Dallas, TX

1:30 PM

Board # 3056

Social Isolation Independently Predicts Incident Heart Failure Among Older Women: Findings From the Womens Health Initiative Study

**Crystal W Cene** , Univ of North Carolina at Chapel Hill, Chapel Hill, NC; Xiaoyan Iris Leng, Wake Forest Sch of Med, Wake Forest, NC; Matthew A Allison, Univ of California San Diego, La Jolla, CA; Khadijah Breathett, Univ of Arizona, Tucson, AZ; Chloe Bird, Rand, Santa Monica, CA; Mace C Coday, Univ Tennessee, Memphis, TN; Giselle Corbie-Smith, Univ of North Carolina, Chapel Hill, NC; Randi Foraker, Washington Univ, St. Louis, MO; Nkechinyere N Ijioma, Altru Health System, Grand Forks, ND; Milagros C Rosal, UMASS Medical Sch, Worcester, MA; Shawnita Sealy-Jefferson, Ohio State Univ, Columbus, OH; Candyce H Kroenke, Kaiser Permanente Northern California, Oakland, CA

1:30 PM

Board # 3057

Posttraumatic Stress Disorder is Associated With Mental Stress-Induced Myocardial Ischemia in Men and Women After a Recent Myocardial Infarction

**Bruno B Lima** , Muhammad Hammadah, Brad Pearce, Amit J Shah, Emory Univ, Atlanta, GA; Kasra Moazzami, Emory Univ, Brookhaven, GA; Jeong Hwan Kim, Samaah Sullivan, Oleksiy Levantsevych, Emory Univ, Atlanta, GA; An Young, Emory Univ, Brookhaven, GA; Tene T Lewis, Lisa Elon, Emory Univ, Atlanta, GA; Paolo Raggi, Mazankowski Alberta Heart Inst, Edmonton, AB, Canada; J. Douglas Bremner, Arshed A Quyyumi, Emory Univ, Atlanta, GA; Viola Vaccarino, Emory Univesity, Atlanta, GA

1:30 PM

Board # 3058

Effect of Change in Cumulative Psychosocial Stressors on Change in Body Mass Index Over Time

**Jonathan Z Butler** , Eva M Durazo, UCSF, San Francisco, CA; Rimma Dushkes, Brigham and Women's Hosp, Boston, MA; Natalie Bea Slopen, Univ of Maryland Sch of Public Health, College Park, MD; David R Williams, Harvard T.H. Chan Sch of Public Health, Boston, MA; Tiffany M Powell-Wiley, Natl Insts of Health, Silver Spring, MD; Julie E Buring, Harvard Medical Sch, Boston, MA; Michelle A Albert, UCSF, San Francisco, CA

1:30 PM

Board # 3059

The Impact of Anxiety Disorders on In-Hospital Outcomes in Patients With Myocardial Infarction

**Pengyang Li** , Saint Vincent Hosp, Worcester, MA; Fangcheng Wu, Memorial Hosp West, Pembroke Pines, FL; Lingling Wu, Mount Sinai St Luke's and West, New York, NY; Ying Ning, Saint Vincent Hosp, Worcester, MA; Kristina Duan, Baylor Coll of Med, Houston, TX; Qi Liu, Texas Heart Inst, Houston, TX

1:30 PM

Board # 3060

Stress, Resilience, and Cardiovascular Disease Risk Among Black Women

**Ashley S Felix** , Karen Patricia Williams, Amy Lehman, Timiya S Nolan, Shawnita Sealy-Jefferson, The Ohio State Univ, Columbus, OH; Khadijah Breathett, Univ of Arizona, Tuscon, AZ; Darryl B Hood, The Ohio State Univ, Columbus, OH; Daniel Addison, Ohio State Univ, Columbus, OH; Cindy M Anderson, The Ohio State Univ, Columbus, OH; Crystal W Cené, Univ of North Carolina at Chapel Hill, Chapel Hill, NC; Barbara J Warren, Rebecca D Jackson, The Ohio State Univ, Columbus, OH

1:30 PM

Board # 3061

Examination of Severity of Depression Symptoms, Perceived Stress, and Cardiovascular Health: The African Immigrant Study

Nwakaego Ada Nmezi, Univ of Florida, Gainesville, FL; **Ruth-Alma Turkson-Ocran** , Johns Hopkins Univ, Baltimore, MD; Yvonne Commodore-Mensah, Johns Hopkins Sch of Nursing, Baltimore, MD

1:30 PM

Board # 3062

Discrimination is Associated With High Cardiovascular Disease Risk: The African Immigrant Health Study

**Ruth-Alma N. Turkson-Ocran** , Johns Hopkins Univ, Baltimore, MD; Nwakaego Ada Nmezi, Univ of Florida, Gainesville, FL; Yvonne Commodore-Mensah, Johns Hopkins Sch of Nursing, Baltimore, MD

# Abstract Poster Session

## MP.APS.01 - Diabetes

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1149

**Altered Reticulum-Mitochondria Interactions Contribute to Mitochondrial Ca** 2+ **Signaling Impairment and Diabetic Cardiomyopathy**

Maya Dia, Inserm U1060-CarMeN-OPERA-Lab of Experimental and Clinical Pharmacology, Faculty of Sciences, Bron-Beyrouth, France; Ludovic Gomez, U1060-CarMeN, Bron, France; Helene Thibault, Faculty de, Lyon, France; Bruno Pillot, Christelle Leon, Yves Gouriou, Nolwenn Tessier, Inserm U1060-CarMeN-OPERA, Bron, France; Emily Tubbs, Nadia Bendridi, U1060 INSERM INRA 1397 CarMeN, Pierre Benite, France; Michel Ovize, Explorations Fonctionnelles Cardiov, Lyon, France; Jennifer Rieusset, U1060 INSERM INRA 1397 CarMeN, Pierre Benite, France; **Melanie Paillard** , Inserm U1060-CarMeN-OPERA, Bron, France

1:30 PM

Board # 1150

Insulin Therapy is Associated With Increased Cardiomyocyte Apoptosis and Cardiac Fibrosis

**Fadi W. Adel** , Ye Zheng, Shuchong Pan, Siu-Hin Wan, Syed Ameenuddin, Horng Chen, Mayo Clinic, Rochester, MN

1:30 PM

Board # 1151

Neurofibromin 2 Regulates Metabolism in the Heart

**Yu Zhang** , Wataru Mizushima, Shinichi Oka, Rutgers New Jersey Medical Sch, Newark, NJ; Peiyong Zhai, Newark, NJ; Dominic Del Re, Rutgers, Newark, NJ

1:30 PM

Board # 1152

Human Resistin Induces Mitochondrial Dysfunction via Cyclase-associated Protein 1-mediated Fission

**Han-Mo Yang** , Joonoh Kim, Seoul Natl Univ Hosp, Seoul, Korea, Republic of; Sahmin Lee, Asan Medical Ctr, Seoul; Hyo Soo Kim, Seoul Natl Univ Hosp, Seoul, Korea, Republic of

1:30 PM

Board # 1153

Berardinelli-seip Congenital Lipodystrophy 2 is Essential in Regulating Cardiac Substrate Metabolism and Function

**Hongyi Zhou** , Jie Li, Huabo Su, Augusta Univ, Augusta, GA; Ji Li, Univ of Mississippi Med Ctr, Jackson, MS; Martin E Young, Univ Alabama Birmingham, Birmingham, AL; Weiqin CHEN, Augusta Univ, Augusta, GA

1:30 PM

Board # 1154

Genetic Disruption of Histone Deacetylase 6 Protects the Heart by Preserving Mitochondrial Complex I During Ischemia/reperfusion Injury in Diabetes

**Zhi-Dong Ge** , Northwestern Univ, Chicago, IL; Shelley L Baumgardt, Yanan Liu, Shigang Qiao, Zeljko J Bosnjak, Judy Kersten, Medical Coll of Wisconsin, Milwaukee, WI; Joseph Matthew Forbess, Lurie Children's Hosp, Chicago, IL

1:30 PM

Board # 1155

High Fat, High Sucrose Diet Alters Hyaluronan Metabolism in Fibroblasts and Promotes Ventricular Dilatation

Yi Wei Zheng, Kenneth Brittian, Andrea Jurkovic, Univ of Louisville, Louisville, KY; Tyler Weirick, Cardiovascular Innovation Inst, Louisville, KY; Shizuka Uchida, Univ of Louisville, Louisville, KY; Matthew A Nystoriak, Louisville Univ, Louisville, KY; Steven P Jones, Robert Brainard, **Sujith Dassanayaka** , Univ of Louisville, Louisville, KY

1:30 PM

Board # 1156

Elevated Plasma β-hydroxybutyrate Levels Predict Adverse Outcomes and Progression in Patients With Arrhythmogenic Cardiomyopathy

**Liang Chen** , Shengshou Hu, Fuwai hospital, Chinese Acad of Medical Sciences and Peking Union Medical Coll, Beijing, China

1:30 PM

Board # 1157

Estrogen-Related Receptor Signaling is Critical for Postnatal Cardiac Maturation

**Timothy R Matsuura** , Tomoya Sakamoto, David M Ryba, Shibiao Wan, Daniel P Kelly, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 1158

The Effect of Empagliflozin on Myocardial Extracellular Matrix Expansion in Patients With Type 2 Diabetes and Coronary Artery Disease

**Tamique Mason** , Subodh Verma, Andrew T Yan, Biswajit Chowdhury, Fei Zuo, St. Michael's Hosp, Toronto, ON, Canada; Kevin E Thorpe, St Michael's Hosp, Univ of Toronto, Toronto, ON, Canada; Otavio R Coelho-Filho, UNICAMP, Campinas, Brazil; Michael Jerosch-Herold, Brigham & Women's Hosp, Boston, MA; Lawrence A Leiter, Univ of Toronto, Toronto, ON, Canada; Bernard Zinman, Mount Sinai Hosp,Univ Toronto, Toronto, ON, Canada; Peter Juni, St. Michael's Hosp - Applied He, Toronto, ON, Canada; Adrian Quan, St. Michael's Hosp, Toronto, ON, Canada; Hwee Teoh, St Michaels Hosp, Toronto, ON, Canada; David Mazer, St Michael's Hosp, Toronto, Toronto, ON, Canada; Kim A Connelly, St. Michael's Hosp, Toronto, ON, Canada

1:30 PM

Poster Professor

Heinrich Taegtmeyer, Houston, TX

1:30 PM

Board # 1159

Divergent Metabolic Programming in Pediatric and Adult Non-Ischemic Dilated Cardiomyopathy

**Kathryn C. Chatfield** , Univ of Colorado Denver, Anschutz Medical Campus, Aurora, CO; Amrut V Ambardekar, Colorado Univeristy, Aurora, CO; Michael J. Bennett, Children's Hosp of Philadelphia, Philadelphia, PA; Michael R Bristow, Univ Colorado-AMC, Aurora, CO; Anastacia M Garcia, Univ of Colorado, Aurora, CO; Anis Karimpour-Fard, Shelley D Miyamoto, Elisabeth K. Phillips, Univ of Colorado Denver, Anschutz Medical Campus, Aurora, CO; genevieve Sparagna, Univ of Colorado Anschutz Med, Aurora, CO; Brian Lee Stauffer, Univ of Colorado, Aurora, CO

# Abstract Poster Session

## IM.APS.01 - Echocardiography of Valves

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4139

Advanced Imaging Protocols for Early Detection of Diastolic and Systolic Dysfunction in Animal Models of Aortic Valve Stenosis

**Runqing Huang** , Liu Bei, Bin Zhang, Carolyn M Roos, Jordan D Miller, Mayo Clinic, Rochester, MN

1:30 PM

Board # 4140

Relationship Between Left Ventricular Diastolic Intra-Ventricular Pressure Gradient Just After Aortic Valve Closure Using Vector Flow Mapping and Left Ventricular Diastolic Suction in Humans

**Takeshi Hozumi** , Yuki Nozawa, Kazushi Takemoto, Wakayama Medical Univ, Wakayama, Japan; Suwako Fujita, Wakayama Medical Univ, Osaka, Japan; Wada Teruaki, Wakayama Medical Univ, Wakayama, Japan; Manabu Kashiwagi, Wakayama Medical Univ, Wakayama City, Japan; Kunihiro Shimamura, Yasutsugu Shiono, Akio Kuroi, Yoshiki Matsuo, Yasushi Ino, Takashi Kubo, Atsushi Tanaka, Takashi Akasaka, Wakayama Medical Univ, Wakayama, Japan

1:30 PM

Board # 4141

Paradoxical Low-flow Low-gradient Aortic Stenosis: Improvement in Indexed Stroke Volume After Trans-catheter Aortic Valve Replacement is Inversely Related to the Number of Conditions Contributing to Low Transvalvular Flow

**Nisha Hosadurg** , Dou Huang, Kristen Brown, Tufts Medical Ctr, Boston, MA; Andrew Ross Weintraub, Tufts Medical Ctr Boston MA, Boston, MA; Ayan R Patel, Benjamin S Wessler, Tufts Medical Ctr, Boston, MA

1:30 PM

Board # 4142

Determinants of Prosthesis-Patient Mismatch in Patients Undergoing Edwards Sapien and Sapien 3 Transcatheter Aortic Valve Replacement

**Srilakshmi Vallabhaneni** , Marsel Matka, Purujit Thacker, Srinidhi Meera, Matthew Carey, Christopher Sarnoski, Raymond Durkin, Michael Durkin, Stephen Olenchock, Jose Amortegui, Raymond J Fitzpatrick, Jamshid Shirani, St Luke's Univ Health Network, Bethlehem, PA

1:30 PM

Board # 4143

Virtual Reality for Visualization and Assessment of Mitral Valve Geometry in Structural Heart Disease

**Ahmed H Aly** , Robert C Gorman Jr., Michael Stauffer, Prakash A Patel, Joseph H Gorman III, Robert C Gorman, Alison M Pouch, Perelman Sch of Med, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 4144

In vitro **Assessment of Proximal Isovelocity Surface Area (PISA) Method on Double Orifice Mitral Regurgitation: Implication for Mitral Clipping**

**Jeesoo Lee** , Northwestern Univ, Chicago, IL; Nadia El Hangouche, Lowie M. R. Van Assche, Northwestern Memorial Hosp, Chicago, IL; Ellie O'Brien, Northwestern Univ Feinberg Sch of Med, Chicago, IL; Alexander J Barker, Children's Hosp Colorado, Denver, CO; Michael Markl, Northwestern Univ, Chicago, IL; James D Thomas, Northwestern Memorial Hosp, Chicago, IL

1:30 PM

Board # 4145

Clinical Factors Impacting Outcome in Functional Mitral Regurgitation; Comparison of Ischemia and Nonischemic Patients

**Sachiyo Igata** , UC San Diego, La Jolla, CA; Bruno R Cotter, Univ California San Diego, La Jolla, CA; Calvin T Hang, Univ of California, San Diego, La Jolla, CA; Monet Strachan, Ajit Raisinghani, UC San Diego, La Jolla, CA; Daniel G Blanchard, UC San Diego, San Diego, CA; Anthony N Demaria, UCSD Sch of Med, La Jolla, CA

1:30 PM

Board # 4146

Characteristics of Patients With Primary Mitral Regurgitation With Early Failure of Mitral Valve Repair: A Matched Comparison Study

**Agostina M. Fava** , A Marc Gillinov, Per Wierup, Brian P. Griffin, Milind Y. Desai, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 4147

Comprehensive Evaluation of Tricuspid Regurgitation Location and Severity Using Vena Contracta Analysis: A Color Doppler 3-dimensional Transesophageal Echocardiography Study

**Hiroto Utsunomiya** , Yu Harada, Hitoshi Susawa, Yusuke Ueda, Kanako Izumi, Kiho Itakura, Hiroki Ikenaga, Takayuki Hidaka, Yukihiro Fukuda, HIROSHIMA UNIVERSITY HOSPITAL, Hiroshima, Japan; Takahiro Shiota, CEDARS-SINAI MEDICAL CENTER, Los Angeles, CA; Yasuki Kihara, HIROSHIMA UNIVERSITY HOSPITAL, Hiroshima, Japan

1:30 PM

Board # 4148

Strain Imaging Detects More Frequently Right Ventricular Systolic Dysfunction Than 3-Dimensional Ejection Fraction in Patients With Significant Functional Tricuspid Regurgitation

**Kensuke Hirasawa** , Philippe V Rosendael, Marlieke F Dietz, Nina A Ajmone Marsan, Victoria Delgado, Leiden Univ Medical Ctr, Leiden, Netherlands; Jeroen J Bax, Leids Univ Medisch Centrum, Leiden, Netherlands

1:30 PM

Poster Professor

Marie Annick Clavel, Quebec, QC, Canada

1:30 PM

Board # 4149

Correlation Between Cine and TEE Measurements of Left Atrial Appendage Closure Device Landing Zone

**Omar Kreidieh** , Ashish Shah, Mariam Wassef, Newark Beth Israel Medical Ctr, Newark, NJ; Constantinos Costeas, David Dobesh, Saint Barnabas Medical Ctr, Livingston, NJ

1:30 PM

Board # 4150

Echocardiographic Parameters and Oxygen Consumption in Patients With Heart Failure With Preserved Ejection Fraction: Insights From the RELAX Trial

**Lily NT Dastmalchi** , George Washington Univ, Washington, DC; Talal Alzahrani, George Washington Univ, Arlington, VA; Jannet F Lewis, George Washington Univ Medical Ctr, Washington, DC; Brian Choi, George Washington Univ, Washington, DC

# Abstract Poster Session

## IM.APS.04 - Emerging Echocardiographic Approaches - Strain

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4176

Shear Wave Elastography With Intracardiac Echocardiography Characterizes Atrial Stiffness During Catheter Ablation For Atrial Fibrillation

**Young-Joong Kim** , Patrick D Wolf, Duke Univ, Durham, NC; Tristram D Bahnson, Duke Univ Medical Ctr, Durham, NC

1:30 PM

Board # 4177

Alteration of Cardiac Performance and Serum B-type Natriuretic Peptide Level in Healthy Aging; Speckle-tracking Echocardiographic Study

**Yuriko Yoshida** , Koki Nakanishi, Masao Daimon, Jumpei Ishiwata, Naoko Sawada, Megumi Hirokawa, Hidehiro Kaneko, The Univ of Tokyo, Tokyo, Japan; Tomoko Nakao, The Univ of Tokyo Hosp, Tokyo, Japan; Yoshiko Mizuno, Hiroyuki Morita, The Univ of Tokyo, Tokyo, Japan; Marco Di Tullio, Columbia Presbyterian Med Ctr, New York, NY; Shunichi Homma, Columbia Univ, New York, NY; Issei Komuro, The Univ of Tokyo, Tokyo, Japan

1:30 PM

Board # 4178

Chronic E-cigarette Users Exhibit Abnormal Myocardial Blood Flow With Stress

**Mohamad Rashid** , Katherine Davoren, Norma B. Moy, Fida Nafeh, Cedars-Sinai Medical Ctr, Los Angeles, CA; Robert Elashoff, UCLA Sch of Public Health, Los Angeles, CA; Chulkyu Kim, Andy Kim, Elizabeth Kim, Cedars-Sinai Medical Ctr, Los Angeles, CA; Michael D Nelson, UT Arlington, Mansfield, TX; Susan Cheng, Florian Rader, Cedars-Sinai Medical Ctr, Los Angeles, CA

1:30 PM

Board # 4179

The Utility of Strain Echocardiography in Follow up for Esophageal Cancer Patients Treated With Mediastinal Radiation Therapy

**Sarah Hale** , Nadia El Hangouche, Anjan Tibrewala, John P. Hayes, Victoria Villaflor, Arushi Singh, Lua Jafari, Katherine McGee, Northwestern Univ Feinberg Sch of Med, Chicago, IL; Juan Lopez-Mattei, MD Anderson Cancer Ctr, Houston, TX; Nausheen Akhter, Northwestern Univ Feinberg Sch of Med, Chicago, IL

1:30 PM

Board # 4180

Usefulness of Cardiac Ultrasound Strain Analysis for Determining the Appropriateness of Coronary Intervention in Assessing Underlying Myocardial Ischemia

**Toshihiko Hamada** , Hokuriku Univ, Kanazawa, Japan; Hiroyasu Uzui, Univ of Fukui, Fukui, Japan; Yuka Ootake, Hokuriku Univ, Fukui, Japan; Hiroyuki Ikeda, Kentarou Ishida, Hideki Kimura, Hiroshi Tada, Univ of Fukui, Fukui, Japan

1:30 PM

Board # 4181

Mitral Regurgitation in Acute Heart Failure: Impact on Left Atrial Dynamics and Response to Treatment

**Maurizio Losito** , IRCCS Policlinico San Donato, Milano, Italy; Monica Barki, Cardiology Univ Dept, Segrate Milan, Italy; Andrea Giammarresi, Cardiology Univ Dept, San Donato Milanese, Italy; valentina labate, IRCCS Policlinico San Donato, San Donato, Italy; Maria Michela Caracciolo, Cardiology Univ Dept, Milan, Italy; Francesco Bandera, IRCCS Policlinico San Donato, Varese, Italy; Alessandro Vella, IRCCS Policlinico San Donato, Milan, Italy; Eleonora Alfonzetti, Cardiology Univ Dept, Milan, Italy; Marina Rovida, Cardiology Univ Dept, San Donato Milanese, Italy; Marco Guazzi, IRCCS Policlinico San Donato, Milano, Italy

1:30 PM

Board # 4182

Mechanical Dispersion Differences Among Vendors in Patients With Left Ventricular Hypertrophy

**Yoshihito Saijo** , Cleveland Clinic, Cleveland, OH; Brett Sperry, Mid America Heart Inst, Kansas City, MO; Dermot Phelan, Milind Desai, Brian P. Griffin, Richard Allen Grimm, Kimi Sato, Zoran B Popovic, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 4183

Left Atrial Strain is Associated With Atrial Fibrosis and MicroRNA-21 Expression in Cardiovascular Surgery Patients

Suguru Hirose, **Toshiaki Nakajima** , Akiko Haruyama, Hiroyuki Kaneda, Syotarou Obi, Takahisa Nasuno, Shu Inami, Ikuko Shibasaki, Takuo Arikawa, Satoshi Sakuma, Shigeru Toyoda, Dokkyo Medical Univ, Tochigi, Japan; Masao Nishimura, Nishimura Heart Clinic, Ageoshi, Japan; Hirotsugu Fukuda, Shichirou Abe, Teruo Inoue, Dokkyo Medical Univ, Tochigi, Japan

1:30 PM

Board # 4184

Three-dimensional Cardiac Mechanics for Prediction of Events in Chagas Disease

**Viviane T Hotta** , Maria Cristina D Abduch, Marcelo Luiz C Vieira, Insto do Coração, São Paulo, Brazil; Barbara Maria Ianni, Heart Inst (InCor), Sao Paulo, Brazil; Charles Mady, Insto do Coração, São Paulo, Brazil; Edimar A Bocchi, Heart Inst, Sao Paulo, Brazil

1:30 PM

Board # 4185

Is Myocardial Work a Determinant of Exercise Capacity?

**Amera Halabi** , Leah Wright, Thomas H Marwick, Baker Heart and Diabetes Inst, Melbourne, Australia

# Abstract Poster Session

## HY.APS.01 - Emerging Treatments for Hypertension

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2145

Differences in Pharmacological Potency Influence Blood Pressure Response to Celecoxib and Naproxen

**Katherine N Theken** , Soumita Ghosh, Carsten Skarke, Susanne Fries, Nicholas F Lahens, Dimitra Sarantopoulou, Gregory R Grant, Garret A FitzGerald, Tilo Grosser, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 2146

Endothelial Colony-forming Cells in Hypertension: A Platform of in-vitro Angiogenesis Assessment and Mechanism Discovery

**Cheryl Tan** , Adam J Lewandowski, Wilby Wiliamson Oxford, Odaro John Huckstep, Maryam Alsharqi, Afifah Mohamed, Paul Leeson, Univ of Oxford, Oxford, United Kingdom; Mariane Bertagnolli, CIUSSS Nord-de-l'Île-de-Montréal, Montréal, QC, Canada

1:30 PM

Board # 2147

Efficacy of Calcium Channel Blockers in Comparison to Renin-Angiotensin System Inhibitors on Urinary Albumin Excretion in Hypertensive Patient With Diabetic Nephropathy. A Meta-Analysis of Randomized Control Trials

**Eder H Cativo Calderon** , Persio David Lopez Loyo, Icahn Sch of Med Mount Sinai, New York, NY; Diana Otero, Mount Sinai Hosp, New York, NY; Steven A Atlas, Mount Sinai Sch Med, Bronx, NY; Clive Rosendorff, Icahn Sch. of Med. at Mount Sinai, New York, NY

1:30 PM

Board # 2148

PRN Use of Antihypertensive Medications is Associated With Increased Mortality and Adverse Outcomes

**Rajesh Mohandas** , Shahab Bozorgmehri, Gajapathiraju Chamarthi, Tezcan Ozrazgat-Baslanti, Rupam Ruchi, Ashutosh M Shukla, Amir Kazory, Azra Bihorac, Mark S Segal, Univ of Florida, Gainesville, FL

1:30 PM

Board # 2149

Hypertensive Diseases in Pregnancy and Renal Function Later in Life: Insights From the Genetic Epidemiology Network of Arteriopathy Study

**Adebamike Adedayo Oshunbade** , Seth T Lirette, Arsalan Hamid, Univ of Mississippi Medical Ctr, Jackson, MS; Semiu O Gbadamosi, Florida Intl Univ, Miami, FL; Olusola Orimoloye, Johns Hopkins Univ, Baltimore, MD; Martin Tibuakuu, St. Luke's Hosp, Ballwin, MO; Daisuke Kamimura, Yokohama City Univ Hosp, Yokohama, Japan; Donald CLARK III, Wondwosen K Yimer, Univ of Mississippi Medical Ctr, Jackson, MS; Stephen D Grado, Univ of Mississippi Sch of Med, Jackson, MS; Elizabeth A Lutz, Univ of Mississippi Medical Ctr, Jackson, MS; Robert J Mentz, Duke Clinical Res Inst, Hillsborough, NC; Ervin R Fox, Javed Butler, Kenneth R Butler, Thomas H Mosley Jr, Michael E Hall, Univ of Mississippi Medical Ctr, Jackson, MS

1:30 PM

Board # 2150

Relationship Between the Duration of Hypertension and Cerebral and Cardiovascular Disease in the Adult Korean Population: From the Korean National Health and Nutritional Examination Survey 2007-2014

**Seung Woon Rha** , Byoung Geol Choi, Se Yeon Choi, Jae Kyeong Byun, Jinah Cha, Yoonjee Park, Dong Oh Kang, Won-Young Jang, Woohyeun Kim, Ja Yeon Choi, Jin Oh Na, Cheol Ung Choi, Chang Gyu Park, Hong Seog Seo, Korea Univ Guro Hosp, Seoul, Korea, Republic of

1:30 PM

Board # 2151

The Anti-Hypertensive Effects of LCZ696 in Patients With Hypertension: A Meta-Analysis of Randomized Controlled Trials

**Su-Kiat Chua** , Chiung-Zuan Chiu, Shin-Kong Memorial Hosp, Taipei, Taiwan

1:30 PM

Poster Professor

Ji Li, Tampa, FL

1:30 PM

Board # 2152

Development Of Hypertension And Modulation Of Sodium Excretion In Response To Angiotensin Ii Are Dependent On Chloride Intake

Jessica Liberona, Patricio A Araos Sr., Rodrigo Ricardo Alzamora, Andres Stutzin, **Luis Michea** , Univ De Chile, Santiago, Chile

1:30 PM

Board # 2153

Data-Driven Trajectories Modeling of On-Treatment Systolic Blood Pressure and Cardiovascular Risks in Sprint and Accord: Similar Pattern in Different Trials

**Xiaodong Zhuang** , First Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China; Lizhen Liao, Guangdong Pharmaceutical Univ, Guangzhou Higher Education Mega Ctr, Guangzhou, China; Yuehua Dong, Sch of Mathematics, Southern China Ctr for Statistical Science, Sun Yat-sen Univ, Guangzhou, China; Xin Xue Liao, First Affiliated Hosp, Sun Yat-sen Univ, Guangzhou, China

1:30 PM

Board # 2154

Trends in Initiation of Antihypertensive Medication With Combination Therapy in a US Integrated Healthcare System

**Jaejin An** , Kristi Reynolds, Kaiser Permanente, Pasadena, CA; Rong Wei, Kaiser Permanente So. California, Pasadena, CA; Tiffany Luong, Kaiser Permanente Southern Californ, Pasadena, CA; Lei Qian, Kaiser Permanente, Pasadena, CA; Jeff Brettler, Kaiser Permanente, Pasadena, CA, Los Angeles, CA; Marc Jaffe, Resolve to Save Lives, New York City, NY; Paul Muntner, Univ Alabama Birmingham, Birmingham, AL

# Abstract Poster Session

## EP.APS.02 - Epidemiology of Atrial Fibrillation

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Alan S Go, Oakland, CA

1:30 PM

Board # 3043

Cardiorespiratory Fitness, Obesity, and Incidence of Atrial Fibrillation

**Shirit Kamil-Rosenberg** , Palo Alto VA Health System, Palo Alto, CA; Peter Kokkinos, Washington DC VA Medical Ctr, Washington, DC; Christina de Souza e Silva, Win Leth Shwe Yee, Palo Alto VA Health System, Palo Alto, CA; Joshua Abella, VA Hosp, Palo Alto, CA; Khin Nyein Chan, VA Hosp, Santa Clara, CA; Jonathan N Myers, VA Palo Alto Health Care System, Palo Alto, CA

1:30 PM

Board # 3044

Quantifying the Risk of Ischemic Stroke Attributed to Lack of Oral Anticoagulation Use in the Southern Part of the US Among Atrial Fibrillation Patients

**Jingchuan Guo** , Meiqi He, Jared W Magnani, Walid F Gellad, Inmaculada Hernandez, Univ of Pittsburgh, Pittsburgh, PA

1:30 PM

Board # 3045

Serum NT-proBNP Level is a Predictor for Developing Atrial Fibrillation in a General Japanese Population: The Hisayama Study

**Takuya Nagata** , Jun Hata, Satoko Sakata, Emi Oishi, Takanori Honda, Yoshihiko Furuta, Tomoyuki Ohara, Daigo Yoshida, Yoichiro Hirakawa, Mao Shibata, Tomomi Ide, Kyushu Univ, Fukuoka, Japan; Takanari Kitazono, Kyushu Univ Sch of Med, Fukuoka-shi, Japan; Hiroyuki Tsutsui, Toshiharu Ninomiya, Kyushu Univ, Fukuoka, Japan

1:30 PM

Board # 3046

Erectile Dysfunction is Independently Associated With Incident Atrial Fibrillation: The Multi-ethnic Study Of Atherosclerosis (mesa)

**Yoshihiro Tanaka** , Joshua Bundy, Norrina Allen, Northwestern Univ, Chicago, IL; S M Iftekhar Uddin, David Feldman, Erin Michos, Johns Hopkins Sch of Med, Baltimore, MD; Susan Heckbert, Univ of Washington, Seattle, WA; Philip Greenland, Feinberg Sch of Med, Chicago, IL

1:30 PM

Board # 3047

Psoriatic Arthritis Increases the Risk of Incident Atrial Fibrillation - A Community-based Study

**Zhenzhen Wang** , Hon-Chi Lee, Bernard J Gersh, Kenneth J Warrington, Hirohito Kita, Douglas L Packer, Eddie L Greene, Cynthia S Crowson, Rowlens M Melduni, Mayo Clinic, Rochester, MN

1:30 PM

Board # 3049

Non-Alcoholic Fatty Liver Disease and Atrial Fibrillation. Prevalence and Impact on Clinical Outcomes

**Daniele Pastori** , Sapienza Univ of Rome, Rome, Italy; Angela Sciacqua, Univ Magna Græcia of Catanzaro, Catanzaro, Italy; Rossella Marcucci, Univ of Florence, Firenze, Italy; Alessio Farcomeni, Sapienza Univ of Rome, Rome, Italy; Francesco Perticone, Univ Magna Græcia of Catanzaro, Catanzaro, Italy; Maria Del Ben, Sapienza Univ of Rome, Rome, Italy; Francesco Angelico, Univ La Sapienza, Rome, Italy; Pasquale Pignatelli, Sapienza Univ, Rome, Italy; Francesco Violi, Sapienza Univ Rome, Rome, Italy; ATHERO-AF

1:30 PM

Board # 3050

Value of BNP in Prediction of Major Bleeding Events Among Patients With Atrial Fibrillation in the Era of Direct Oral Anticoagulants

**Hiroshi Miyama** , Seiji Takatsuki, Takehiro Kimura, Nobuhiro Ikemura, Yoshinori Katsumata, Ikuko Ueda, Kenji Hashimoto, Terumasa Yamashita, Keio Univ Sch of Med, Tokyo, Japan; Taishi Fujisawa, Keio Univ Hosp, Tokyo, Japan; Kazuaki Nakajima, Keio Univ Sch of Med, tokyo, Japan; Hideaki Kanki, Saitama City Hosp, Saitama, Japan; Koji Negishi, Yokohama Municipal Citizen's Hosp, Yokohama, Japan; Keiichi Nagami, Keiyu Hosp, Yokohama, Japan; Keiichi Fukuda, Shun Kohsaka, Keio Univ Sch of Med, Tokyo, Japan

1:30 PM

Board # 3051

Effectiveness and Safety of Reduced Dose Rivaroxaban Compared to Vitamin K Antagonists in Patients at High Risk of Bleeding

Nicholas Moore, Patrick Blin, Univ of Bordeaux, Bordeaux, France; **Laurent Fauchier** , Univ of Tours, Tours, France; Frederic Sacher, CHU de Bordeaux, Bordeaux, France; Jean Dallongeville, Inst Pasteur de Lille, Lille, France; Caroline Dureau-Pournin, Regis Lassalle, Marie-Agnes Bernard, Cecile Droz-Perroteau, Univ of Bordeaux, Bordeaux, France

1:30 PM

Board # 3052

Common Drug Interactions of Direct Oral Anticoagulants and Their Impact on Clinical Outcomes in Atrial Fibrillation

**David Sanborn** , Mayo Clinic, Rochester, MN; Alan Sugrue, Mayo Clinic Rochester, Rochester, MN; mustapha amin, Medhat Farwati, Ramila Mehta, Abhishek Deshmukh, Mayo Clinic, Rochester, MN; Haarini Sridhar, Mayo Clinic - Rochester, Rochester, MN; Azza Ahmed, Mayo Clinic Health System, Eau Claire, WI; Malini Madhavan, Mayo Clinic, Rochester, MN

# Abstract Poster Session

## GE.APS.01 - Genetic Epidemiology, Genomics and Pharmacogenomics I

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1127

Integrative Epidemiological and Functional Analyses Identify Protein C as a Novel, Causal Factor in Arterial and Venous Disease

**Dirk S Paul** , David Stacey, Lingyan Chen, Joanna M Howson, Amy M Mason, Stephen Burgess, Univ of Cambridge, Cambridge, United Kingdom; NIHR BioResource; INVENT; ARIC Study; INTERVAL Study; John Danesh, Univ of Cambridge, Cambridge, United Kingdom

1:30 PM

Board # 1128

Myocarditis is Associated With Damaging Variants in Cytoskeletal Cardiomyocyte Genes

**Amy Rosen Kontorovich** , Nihir Patel, Mount Sinai Sch of Med, New York, NY; Jeffrey A Towbin, Le Bonheur Childrens Hosp, Memphis, TN; Enkhsaikhan Purevjav, Univ of Tennessee Health Science, Memphis, TN; Karin Klingel, Dept. of Molecular Pathology, Tuebingen; Bruce D Gelb, Icahn Sch Med, New York, NY

1:30 PM

Board # 1129

Apolipoprotein L1 Risk Alleles Are Associated With Risk of Plaque Rupture in Coronary Artery Disease

**Liang Guo** , CVPath Inst, Gaithersburg, MD; Marco Delsante, Azienda Ospedaliera-Univria, Parma, Italy; Anne Cornelissen, Xiaoqing Zhao, Robert Kutys, Raquel Fernandez, Ka Hyun Paek, Atsushi Sakamoto, Hiroyuki Jinnouchi, Dipti Surve, Maria E Romero, Frank D Kolodgie, CVPath Inst, Gaithersburg, MD; Myung K Shin, Maarten Hoek, Merck & Co., Inc., Kenilworth, NJ; Jeffrey B Kopp, Natl Inst of Health, Bethesda, MD; Avi Z Rosenberg, Johns Hopkins Univ Sch of Med, Baltimore, MD; Harry R Davis, Renu Virmani, Aloke V Finn, CVPath Inst, Gaithersburg, MD

1:30 PM

Board # 1130

**Clinical and Functional Reassessment of Alleged Type 5 Long QT Syndrome-Causative Genetic Variants in the** KCNE1 **-Encoded Mink Beta-Subunit**

**John Giudicessi** , Ramin Garmany, Dan Ye, Wei Zhou, Mayo Clinic, Rochester, MN; David Tester, Mayo Clinic Coll of Med, Rochester, MN; Michael John Ackerman, Mayo Clinic, Rochester, MN

1:30 PM

Board # 1131

Familial Hypercholesterolemia Patients Respond to a Free Genetic Testing Offer

**Samuel Gidding** , Amanda Sheldon, FH Fndn, Pasadena, CA; Sherman Law, Cynthia Neben, Alicia Zhou, Color Genomics, Burlingame, CA; Katherine A Wilemon, The FH Fndn, Pasadena, CA; Catherine D Ahmed, FH Fndn, Pasadena, CA; Iris Kindt, The FH Fndn, Pasadena, CA

1:30 PM

Board # 1132

Use of the AHA Pegasis Pipeline to Identify Genetic Associations With Severe 3-Vessel Coronary Artery Disease in High-Risk Pedigrees Free From Myocardial Infarction: The ProGENE Study

**Stacey Knight** , Raymond O McCubrey, Intermountain Medical Ctr, Salt Lake City, UT; Robert Sargent, Univ of Utah, Salt Lake City, UT; Daniel Bride, Intermountain Healthcare, Murray, UT; Michael Madsen, Huntsman Cancer Inst, Salt Lake City, UT; John Gardner, Univ of Utah, Salt Lake City, UT; Joseph Brent Muhlestein, Jeffrey Lance Anderson, Benjamin D Horne, Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT; Nicola Camp, Univ of Utah, Salt Lake City, UT; Kirk Ute Knowlton, Intermountain Medical Ctr, Salt Lake City, UT

1:30 PM

Board # 1133

Apolipoprotein E Genotype, Lipoproteins, and Inflammation

**Andrew S Geller** , Lihong He, Ernst J Schaefer, Boston Heart Diagnostics, Framingham, MA

1:30 PM

Board # 1134

Initial Assessment of Diagnostic Yield of Arrhythmogenic Right Ventricular Cardiomyopathy in Patients Ascertained Through Secondary Genomic Findings

**Dominik Beer** , Marci Schwartz, Melissa Kelly, Megan McMinn, Eric Carruth, Amro Alsaid, Martin Matsumura, Brandon Fornwalt, Amy Curry Sturm, Christopher M Haggerty, Geisinger, Danville, PA

1:30 PM

Board # 1135

Validation Of Flag, Identify, Network, Deliver: Find FH Using The Electronic Medical Record To Identify Familial Hypercholesterolemia Within A Single Healthcare System

Samip Sheth, Univ of Pennsylvania, Philadelphia, PA; Lars Andersen, Ezim Ajufo, Philadelphia, PA; Amanda Baer, Matt Isenberg, Berrido Andrea, Esther Oyerinde, Marita Lynch, Risman Marjorie, Brian Wells, Univ of Pennsylvania, Philadelphia, PA; Yuliya Borovskiy, Penn Med, Philadelphia, PA; Erik Hossain, Lisa Estrella, Univ of Pennsylvania, Philadelphia, PA; heidi testa, Michael Horst, LGH, Lancaster, PA; Cathleen Forney, Univ of Pennsylvania, Lancaster, PA; Barbara Martin, Corey Forsyth, LGH, Lancaster, PA; William Howard, David Staszak, Dave Zuzick, The FH Fndn, Pasadena, CA; **Latoya Williamson** , Benjamin Helm, Pasadena, CA; Norton Kendyl, Jaglinski Kevin, Guillermo Marcogardoqui, Marianne Stef, Grifols, San Marcos, TX; Samuel S Gidding, FH Fndn, Bridgewtr Cor, VT; Marina Cuchel, Univ of Pennsylvania, Narberth, PA; Douglas Jacoby, Jinbo Chen, Penn, Bala Cynwyd, PA; Katherine A Wilemon, Kelly D. Myers, The FH Fndn, Pasadena, CA; Rolf Andersen, tbd, tbd, LA; Daniel J Rader, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 1136

A Missense Variant in IL6R and Protection From Peripheral Artery Disease

**Michael Levin** , Univ of Pennsylvania, Philadelphia, PA; Derek Klarin, Massachusetts General Hosp, Boston, MA; Julie Lynch, VA Salt Lake City Health Care System, Salt Lake City, UT; Katherine Liao, Brigham and Women's Hosp, Boston, MA; Benjamin F Voight, Univ of Pennsylvania, Philadelphia, PA; Christopher J O'Donnell, VA Boston Healthcare System, West Roxbury, MA; Kyong-Mi Chang, Corporal Michael J. Crescenz VA Medical Ctr, Philadelphia, PA; Themistocles L Assimes, Stanford Univ, Palo Alto, CA; Philip S Tsao, Stanford Univ, Stanford, CA; Scott M DAMRAUER, Corporal Michael J. Crescenz VA Medical Ctr, Philadelphia, PA; on behalf of the VA Million Veteran Program

1:30 PM

Poster Professor

Sony Tuteja, Philadelphia, PA

# Abstract Poster Session

## HF.APS.48 - Heart Failure: Risk Prediction

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2075

Clinical and Genetic Determinants of Heart Failure: Optimized by Machine Learning and Mendelian Randomization

**Xiaodong Zhuang** , First Affiliated Hosp, Sun Yat-Sen Univ, Guangzhou, China; Lizhen Liao, Guangdong Pharmaceutical Univ, Guangzhou Higher Education Mega Ctr, Guangzhou, China; Xinxue Liao, First Affiliated Hosp, Sun Yat-Sen Univ, Guangzhou, China

1:30 PM

Board # 2076

Are Obesity and Hypertension Separately Related to Subclinical Left Ventricular Dysfunction?

**Ann Morgenstern** , Jordan Long, Brandon Mikolich, Samuel Kulifay, Alexander Callow, Sharon Regional Medical Ctr, Sharon, PA; J Ronald Mikolich, Northeast Ohio Medical Univ, Youngstown, OH

1:30 PM

Board # 2077

Female Sex, Multiple Sarcomere Variants and Atrial Fibrillation Are Associated With Worse Outcome in Patients With End-Stage Hypertrophic Cardiomyopathy

**Peter Marstrand** , Neal K Lakdawala, Brigham and Women's Hosp, Boston, MA; Sharlene Day, Univ of Pennsylvania, Philadelphia, PA; Euan A Ashley, Stanford Univ, Stanford, CA; Michelle Michels, Erasmus MC Rotterdam, Rotterdam, Netherlands; Alexandre Pereira, Heart Inst (incor), Sao Paulo, Brazil; Samuel Wittekind, Cincinnati Children's Hosp, Cincinnati, OH; Daniel Jacoby, Yale Sch of Med, New Haven, CT; James Simon Ware, Imperial Coll London, London; Steven D Colan, Boston Children's Hosp, Boston, MA; Iacopo Olivotto, Careggi Univ Hosp, Florence, Italy; Christopher Semsarian, Jodie Ingles, Centenary Inst, Sydney, Australia; Carolyn Ho, Brigham and Women's Hosp, Boston, MA

1:30 PM

Board # 2078

Cardiac Screening in Adolescents: Significance of Individual Components of Screens in Identifying Necessary Follow-Up Cardiac Evaluation

Adelle Schade, Univ of the Sciences, Philadelphia, PA; Rachel Kesselring, Conrad Weiser High Sch, Philadelphia, PA; Kristin Racis, Univ of the Sciences, Philadelphia, PA; **Thomas Chin** , Penn State Health, Milton S. Hershey Medical Ctr, Harrisburg, PA

1:30 PM

Board # 2079

Prognostic Role of a TNM-Like Classification for Heart Failure: Comparison With Others Nosologies After 1 Year Follow Up

Paolo Severino, Sapienza Univ, Rome, Italy; Mariateresa Pucci, Rome, Italy; **Marco Valerio Mariani** , Rossana Scarpati, Andrea d'Amato, Lucrezia Netti, Sapienza Univ of Rome, Rome, Italy; Fabio Infusino, Umberto I Hosp, Sapienza, Rome, Italy; Danilo Alunni Fegatelli, Annarita Vestri, Viviana Maestrini, Massimo Mancone, Francesco Fedele, Sapienza Univ of Rome, Rome, Italy

1:30 PM

Board # 2080

Reduced Brain Activity is Associated With Anxiety Status and Cognitive Functionin Patients With Heart Failure as Measured by Near-infrared Spectroscopy

**Tomofumi Misaka** , Akiomi Yoshihisa, Soichi Kono, Yasuhiro Ichijo, Masayoshi Oikawa, Takashi Kaneshiro, Itaru Miura, Hirooki Yabe, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

1:30 PM

Poster Professor

Alanna A Morris, Atlanta, GA

1:30 PM

Board # 2081

Risk Factors and Risk Prediction Models for Incident HFrEF and HFpEF in U.S. Veterans

**Liam Gaziano** , Kelly Cho, Luc Djousse, Ashley Galloway, Yuk-lam Ho, Petra Schubert, Katherine Kurgansky, David Gagnon, Maveric, VA Boston Healthcare System, Boston, MA; Emanuele Di Angelantonio, Angela M. Wood, Univ of Cambridge, Cambridge, United Kingdom; J. Michael Gaziano, Maveric, VA Boston Healthcare System, Boston, MA; Adam Butterworth, Univ of Cambridge, Cambridge, United Kingdom; Peter W. f. Wilson, Jacob Joseph, Maveric, VA Boston Healthcare System, Boston, MA

1:30 PM

Board # 2082

Prognostic Factors in Heart Failure Patients With Cardiac Cachexia

**Yu Sato** , Akiomi Yoshihisa, Yu Hotsuki, Koichiro Watanabe, Yusuke Kimishima, Takatoyo Kiko, Yuki Kanno, Tetsuro Yokokawa, Satoshi Abe, Tomofumi Misaka, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

1:30 PM

Board # 2083

Prognostic Impacts of Dynamic Left Ventricular Structural Changes in Heart Failure Patients With Preserved Ejection Fraction -A Report From the CHART-2 Study-

**Shinsuke Yamanaka** , Yasuhiko Sakata, Kotaro Nochioka, Masanobu Miura, Shintaro Kasahara, Masayuki Sato, Hajime Aoyanagi, Takahide Fujihashi, Hideka Hayashi, Takashi Shiroto, Koichiro Sugimura, Jun Takahashi, Satoshi Miyata, Hiroaki Shimokawa, Tohoku Univ Graduate Sch of Med, Sendai, Japan

1:30 PM

Board # 2084

Association of ProBNP Ratio to Total BNP on Admission With Future Cardiac Reverse Remodeling in Acute Decompensated Heart Failure Patients With Reduced Ejection Fraction: A New Biomarker to Predict Recovery of Left Ventricular Systolic Function

**Akihisa Kimura** , Hiroyuki Takahama, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Toshio Nishikimi, Kyoto Unversity Graduate Sch of Med, Kyoto, Japan; Seiji Takashio, Tomohiro Hayashi, Chiaki Okatani, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Yasuaki Nakagawa, Kyoto Univ Graduate Sch of Med, Kyoto, Japan; Yasuhiro Hamatani, Atsushi Okada, Masashi Amano, Makoto Amaki, Takuya Hasegawa, Hideaki Kanzaki, Satoshi Yasuda, Kenji Kangawa, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Toshihisa Anzai, Hokkaido Univ, Sapporo, Japan; Naoto Minamino, Natl Cerebral and Cardivascular Ctr, Suita, Japan; Chisato Izumi, Natl Cerebral and Cardiovacular Ctr, Suita, Japan

# Abstract Poster Session

## IN.APS.03 - Hot Topics in PCI I

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4234

Causes and Predictors of 30-Day Post-PCI Readmission Rate in Patients With Pulmonary Hypertension- A Nationwide Readmission Database Analysis

**Neel Patel** , Birendra Amgai, Sandipan Chakraborty, Interfaith Medical Ctr, Brooklyn, NY; Soniya Koirala, Tribhuvan Univ Teaching Hosp, Kathmandu, Nepal; Aneeta Kumari, Interfaith Medical Ctr, New York, NY; Dhrubajyoti Bandyopadhyay, Mount Sinai St Luke's Roosevelt, New York, NY, NY; Adrija Hajra, Jacobi Medical Ctr, New York, NY; Eyal Herzog, Mount Sinai St Luke's Roosevelt, New York, NY; Wilbert S Aronow, New York Medical Coll, New York, NY, NY

1:30 PM

Board # 4235

Incidence and Long-term Clinical Impact of Longitudinal Stent Deformation After the Promus Element Platinum Chromium-Everolimus Eluting Stent Implantation

**Takashi Hiromasa** , Shoichi Kuramitsu, Kokura Memorial Hosp, Kitakyushu, Japan; Takenori Domei, Kokura Memorial Hosp, Kitakyusyu, Japan; Kyohei Yamaji, Kokura Memorial Hosp, Kitakyshu, Japan; Shinichi Shirai, Yoshimitsu Soga, Kenji Ando, Kokura Memorial Hosp, Kitakyushu, Japan

1:30 PM

Board # 4236

In-hospital Outcomes Of Conservative Versus Interventional Therapies For Spontaneous Coronary Artery Dissection

**Paul Muutu Ndunda** , Univ of Kansas Sch of Med-Wichita, Wichita, KS; Sinan Khayyat, Univ of Kansas Sch of Med - Wichita, Wichita, KS; Mohinder Vindhyal, Univ of Kansas Sch of Med-Wichita, Wichita, KS; Hayrettin Okut, KU Medical Sch, Wichita, KS; Job Mogire, Univ of Kansas, Andover, KS; Zaher Fanari, Univ of Kansas Wichita, Wichita, KS

1:30 PM

Board # 4237

Mid-Term Outcomes After Percutaneous Coronary Intervention in Cancer Patients

**Raymundo A Quintana Quezada** , Emory Univ, Atlanta, GA; Dominique Monlezun, Univ of Texas at Houston, Houston, TX; Giovanni E Davogustto, Vanderbilt Univ, Nashville, TN; Humberto R Saenz, Univ of California San Diego, San Diego, CA; Francisco Lozano-Ruiz, Medica Sur Hosp, Mexico City, Mexico; Daisuke Sueta, Kumamoto Univ Grad Schl Med Sci, Kumamoto, Japan; Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan; Uri Landes, Rabin Medical Ctr, Petah-tikva, Israel; Ali E Denktas, Mahboob Alam, Baylor Coll of Med, Houston, TX; Daniel Addison, Ohio State Univ, Columbus, OH; David Paniagua, Hani Jneid, Baylor Coll of Med and Michael E. DeBakey VA Medical Ctr, Houston, TX

1:30 PM

Board # 4238

Optimal Two Stent Strategies for Non Left Main Trunc Coronary Bifurcation Lesions Differ According to the Lesion Locations

**Tomohiko Sato** , New Tokyo Hosp, Matsudo, Japan

1:30 PM

Board # 4239

Efficacy and Safety of Intracoronary Thrombolysis as an Adjunctive Therapy to Primary Percutaneous Coronary Intervention in ST- Elevation Myocardial Infarction. A Systematic Review and Meta-Analysis

**Motasem Alyamani** , Sandra Campbell, Univ of Alberta, Edmonton, AB, Canada; Eliano Navarese, Univ of Alberta, Rome, Italy; Robert C Welsh, Mazankowski Alberta Heart Inst, Edmonton, AB, Canada; Kevin R Bainey, Univ of Alberta, Edmonton, AB, Canada

1:30 PM

Board # 4241

Rivaroxaban Plus Aspirin versus With Aspirin in Patients With Prior Percutaneous Coronary Intervention (PCI): Insights From the COMPASS Trial

**Kevin R Bainey** , Univ of Alberta, Edmonton, AB, Canada; Scott Berkowitz, Bayer U.S. LLC, Whippany, NJ; Deepak L Bhatt, Brigham and Womens Hosp, Boston, MA; John W Eikelboom, McMaster Univ HGH, Hamilton, ON, Canada; Keith A Fox, Cardiovasc Res, Nethy Bridge, United Kingdom; Basil S Lewis, Lady Davis Carmel Med Ctr, Haifa, Israel; Tamara Marsden, Population Health Res Inst, Hamilton, ON, Canada; Eva Muehlhofer, BAYER AG, Wuppertal; Dragos Vinereanu, Univea de Medicină, București, Romania; Petr Widimsky, Charles Univ, Prague 10, Czech Republic; Robert C Welsh, Mazankowski Alberta Heart Inst, Edmonton, AB, Canada

1:30 PM

Poster Professor

Khaled M Ziada, Lexington, KY

1:30 PM

Board # 4242

Influence of Ethnicity on the Incidence of Contrast-Induced Acute Kidney Injury After Percutaneous Coronary Intervention

**Davide Cao** , Roxana Mehran, Rishi Chandiramani, Ridhima Goel, Anastasios Roumeliotis, Moritz Blum, Rachel Singleton, George Dangas, Usman Baber, Icahn Sch of Med at Mount Sinai, New York, NY; Giulio G. Stefanini, Humanitas Res Hosp, Milano, Italy; Asaad Khan, Prakash Krishnan, Jason C Kovacic, Nitin Barman, Joseph Sweeny, Vishal Kapur, Choudhury Hasan, Javed Suleman, Srinivas Kesanakurthy, Samin K. Sharma, Annapoorna Kini, Mount Sinai Hosp, New York, NY

# Abstract Poster Session

## EA.APS.01 - ICD and Pacemaker Therapy

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2000

Effects of Cognitive Behavioral and Psycho-Educational Therapy in Patients With Implantable Cardioverter Defibrillators: Systematic Review and Meta-Analysis of Randomized and Quasi-Experimental Trials

**Zahra Azizi** , Hadi Tohidi, Pouria Alipour, Meysam Pirbaglou, Southlake Regional Health Ctr, Newmarket, ON, Canada; Chris Ardern, Michael Rotondi, Paul Ritvo, York Univ, Toronto, ON, Canada; Atul Verma, Southlake Regional Health Ctr, Newmarket, ON, Canada; Yaariv Khaykin, Southlake regional health centre, Richmond Hill, ON, Canada

1:30 PM

Board # 2001

Clinical Features and Echocardiography Predict Defibrillation Failure in ICD Recipients

Deepak Bhakta, Yifei Zhang, **Alexander E Urban** , David E Adams, Elise Hannemann, Indiana Univ Sch of Med, Indianapolis, IN; William J Groh, Medical Univ of South Carolina, Charleston, SC; John M Miller, Indiana Univ Sch of Med, Indianapolis, IN

1:30 PM

Board # 2002

Right-Sided Subcutaneous Implantable Cardioverter-Defibrillator in Patient With Situs Inversus Totalis

**Emrie Tomaiko** , Meenakshi Sridhar, Sharon Kusne, Carla Lockhart, Jonathan Ko, Banner Univ Medical Ctr Phoenix, Phoenix, AZ; Wilber Su, Banner Univ Medical Ctr, Paradise Vly, AZ

1:30 PM

Board # 2003

Inappropriate Sustained Atrial Pacing and Ventricular Safety Pacing During Sustained Ventricular Tachycardia

**Michael Wu** , Brown Univ, Providence, RI; Lauren Rousseau, Cardiovascular Inst, Providence, RI; Antony F Chu, Brown Univ, Providence, RI

1:30 PM

Board # 2004

Indication and Management of Allergy to TYRX Absorbable Antibacterial Envelope

Emrie Tomaiko, **Meenakshi Sridhar** , Carla Lockhart, Sharon Kusne, Jonathan Ko, Banner Univ Medical Ctr Phoenix, Phoenix, AZ; Wilber Su, Banner Univ Medical Ctr, Paradise Vly, AZ

1:30 PM

Board # 2005

Lead Less Pacemaker and Deep Brain Stimulator: A Unique Cohabitations

**Najam U Saqib** , The Wright Ctr, Clarks Green, PA; Muhammad Siddique Pir, The Wright Ctr for GME, Scranton, PA; Abdul Haseeb, The Wright Ctr for Graduate Medical Education, scranton, PA; Wilson Young, Geisinger Community Medical Ctr, scranton, PA

1:30 PM

Board # 2006

Increased Capture Threshold in Selective His-bundle Pacing Associated With Flecainide Acetate

**Michael Jiang** , Northwestern Univ Feinberg Sch of Med, Chicago, IL; Jeremiah Wasserlauf, Northwestern Med, Chicago, IL; Bradley P Knight, Northwestern Med Group, Chicago, IL; Nishant Verma, Northwestern Univ, Chicago, IL

1:30 PM

Board # 2007

Outcomes of His Bundle Pacing in a Low-volume Hospital

**Swee Leng Kui** , Cheok Keng Wong, Colin Yeo, Changi General Hosp, singapore, Singapore; Vern Hsen Tan, Changi General Hosp, Singapore, Singapore

# Abstract Poster Session

## LF.APS.02 - Innovations and Insights into Cardiac Rehabilitation

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3174

Effects of Targeted Strategies in Improving Phase II Cardiac Rehabilitation Program Recruitment in an Asian Multi-ethnic Cohort

Yanhong Huang, **Nur Adawiyah Yusoff** , Yan Cao, Dawn Loh, TeckBee Ang, Mei Mei Foong, Leng Geok Lim, Boon Wah Liew, Jian Jing Tan, Changi General Hosp, Singapore, Singapore

1:30 PM

Board # 3175

Hybrid Cardiac Rehabilitation an Alternative to Center-based Cardiac Rehabilitation: A Systemic Review and Meta-analysis

**Hafiz Muhammad Imran** , Rhode Island Hosp, Providence, RI; Muhammad Baig, The Miriam Hosp, Providence, RI; Nishant R Shah, Sebhat Erqou, Providence Veterans Affairs Medical Ctr, Providence, RI; Wen-Chih Hank Wu, Providence VA Hosp, Providence, RI

1:30 PM

Board # 3176

Right Heart Morphology and Function in Elite Female Athletes: A Systematic Review and Meta-Analysis

**Robyn Bryde** , Abd Moain Abu Dabrh, Andres Applewhite, George Yazji, Rashid Alhusain, Mayo Clinic Florida, Jacksonville, FL; Brian P Shapiro, Mayo Clinic, Jacksonville, FL

1:30 PM

Board # 3177

Clinical and Psychosocial Predictors of Cardiac Rehabilitation Participation

**Sherrie Khadanga** , Patrick Savage, Diann Gaalema, Philip A Ades, Univ of Vermont Medical Ctr, Burlington, VT

1:30 PM

Board # 3178

A Digital Health Intervention to Improve Physical Activity After Cardiac Rehabilitation: The Mobile4heart Clinical Trial

**Linda G Park** , Abdelaziz Elnaggar, UCSF, San Francisco, CA; Stephanie Merek, Dept of Veterans Affairs, San Francisco, CA; Charles E McCulloch, UCSF, San Francisco, CA; Mary A Whooley, UCSF and San Francisco VA, San Francisco, CA

1:30 PM

Board # 3179

Impact of Cardiac Rehabilitation on Reducing Rehospitalization and Subsequent Medical Expenses in Patients With Acute Coronary Syndrome

**Yuya Yokota** , Showa Univ Sch of Med, Tokyo, Japan; Yoshitaka Iso, Showa Univ RISES, Kanagawa, Japan; Fumiyoshi Tsunoda, Makoto Shoji, Showa Univ Div of Cardiology, Tokyo, Japan; Hiroshi Suzuki, Showa Univ Fujigaoka Hosp, Yokohama, Japan; Toshiro Shinke, Shinji Koba, Showa Univ Sch of Med, Tokyo, Japan

1:30 PM

Poster Professor

Pam R Taub, La Jolla, CA

1:30 PM

Board # 3180

The Association of Frailty With All-cause Mortality Among Elderly With Acute Myocardial Infarction: A Systematic Review and Meta-analysis

**Prapaipan Putthapiban** , Einstein Medical Ctr, Philadelphia, PA; Wasawat Vutthikraivit, Texas Tech Health Sciences Ctr, Lubbock, TX; Weera Sukhumthammarat, Einstein Medical Ctr, Philadelphia, PA; Pattara Rattanawong, Univ of Hawaii, Honolulu, HI; Napatt Kanjanahattakij, Einstein Medical Ctr, Philadelphia, PA; Aman Amanullah, Albert Einstein Medical Ctr, Philadelphia, PA

1:30 PM

Board # 3181

Expired Carbon Monoxide: A Novel Approach to Assess Smoking Status in Cardiac Rehabilitation

**Sherrie Khadanga** , Patrick Savage, Jason Rengo, Phillip Ades, Diann Gaalema, Univ of Vermont Medical Ctr, Burlington, VT

1:30 PM

Board # 3182

Effect of Exercise-based Cardiac Rehabilitation After Acute Myocardial Infarction on HDL Function: A Randomized Clinical Trial

Talia Falcão Dalcoquio, Insto do Coracao HCFMUSP, Sao Paulo, Brazil; Fatima Freitas, Flávia Bittar Britto Arantes, Larissa Ferreira-Santos, Leandro Alves, Mayara Santos, Insto do Coração do Hosp das Clínicas da Faculdade de Medicina da Univ de São Paulo (InCor /HCFMUSP), Sao Paulo, Brazil; Maria Urbana P. B. Rondon, Sch of Physical Education and Sport of Univ of São Paulo, Sao Paulo, Brazil; Maria-janieire N Alves, Remo Holanda de Mendonça Furtado, Carlos E Negrao, Raul Cavalcante Maranhão, **José Carlos Nicolau** , Insto do Coração do Hosp das Clínicas da Faculdade de Medicina da Univ de São Paulo (InCor /HCFMUSP), Sao Paulo, Brazil

# Abstract Poster Session

## EA.APS.02 - Insights into Cardiac Dysrhythmias

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2008

Stabilizing Ryanodine Receptor With Dantrolene Prevents Binge Alcohol Induced Atrial Fibrillation in Rats

**Lisa V. Greco** , Allan Migirov, Daniel I Meshoyrer, Ying Li, Todd J. Cohen, Youhua Zhang, NYIT Coll of Osteopathic Med, Old Westbury, NY

1:30 PM

Board # 2009

Predicted Sensitivity of Short, Intermittent Screening for Atrial Fibrillation (AF) in an At-Risk Population

**Giorgio Quer** , Scripps Res, La Jolla, CA; Ben B Freedman, Heart Res Inst Sydney Uni, Sydney, Australia; Steven R Steinhubl, Scripps Res, Lajolla, CA

1:30 PM

Board # 2010

Low-Level Electromagnetic Fields Attenuate the Inducibility of Atrial Fibrillation

**Daniel Sohinki** , Augusta Univ, Augusta, GA; Stavros Stavrakis, Univ of Oklahoma, Oklahoma City, OK; Sunny S Po, Univ Oklahoma, Oklahoma City, OK; Julie Stoner, Benjamin J Scherlag, Univ of Oklahoma, Oklahoma City, OK

1:30 PM

Board # 2011

Low-Level Vagal Nerve Stimulation Decreases Cardiac Ryanodine Receptor Phosphorylation and Atrial Fibrillation Inducibility in a Rat Heart Failure Model

**Lisa V. Greco** , Chenyu Zhang, Ying Li, Kaie Ojamaa, Youhua Zhang, NYIT Coll of Osteopathic Med, Old Westbury, NY

1:30 PM

Board # 2012

A Definitive Test of the Repolarization versus Depolarization Hypothesis in a Whole-heart Model of Brugada Syndrome

**Jose Di Diego** , Lankenau Inst for Medical Res., Wynnewood, PA; Mariana Argenziano, Children's Hosp of Philadelphia, Wynnewood, PA; Megan Tabler, Chen Kui, Lankenau Inst for Medical Res., Wynnewood, PA; Victoria Messerschmidt, Univ of Texas at Arlington, Arlington, TX; Elliot Jerud, Lankenau Heart Inst, Wynnewood, PA; Charles Antzelevitch, Lankenau Inst for Medical Res, Penn Valley, PA

1:30 PM

Board # 2013

Interplay Between Temporal and Spatial Dispersion of Repolarization in the Initiation and Perpetuation of Torsade De Pointes Arrhythmias

**Agnieszka Smoczynska** , Errol W Aarnink, Albert Dunnink, Alexandre Bossu, Valerie Y.h. Weperen, Univ Medical Ctr Utrecht, Utrecht, Netherlands; Veronique Meijborg, Academic Medical Ctr Amsterdam, Amsterdam, Netherlands; Henriëtte D.M. Beekman, Marc A Vos, Univ Medical Ctr Utrecht, Utrecht, Netherlands

1:30 PM

Board # 2014

Morphological and Electrophysiological Characterization of Homozygous Lamin A/C Knockout Human Induced-Pluripotent Stem Cell-Derived Cardiomyocytes

**Yimin Wuriyanghai** , Kyoto Univ Hosp, Kyoto, Japan; Takeru Makiyama, Kyoto Univ Graduate Sch of Med, Kyoto, Japan; Yuta Yamamoto, Kyoto Univ, Kyoto, Japan; Hirohiko Kohjitani, Kyoto Univ Hosp, Kyoto, Japan; Sayako Hirose, Kyoto Univ Graduate Sch of Med, Sakyo-ku, Kyoto, Japan; Jingshan Gao, Asami Kashiwa, Hai Huang, Takanori Aizawa, Tomohiko Imamura, Kyoto Univ Graduate Sch of Med, Kyoto, Japan; Seiko Ohno, NCVC, Suita, Japan; Minoru Horie, Shiga Univ of Medical Science, Ohtu, Japan; Takeshi Kimura, Kyoto Univeristy, Kyoto, Japan

1:30 PM

Board # 2015

Electrical Cardioversion for Atrial Fibrillation; Initial and Subsequent Change in Transthoracic Impedance Predicts the Likelihood to Require Charge Escalation to High Energies During External Defibrillation

**Assad Mohammedzein** , Katie Walsh, Abushama Abubakr, Patrick Owens, Univ Hosp Waterford, Waterford, Ireland

# Abstract Poster Session

## CA.LBBS.APS - Late-Breaking Basic Science Posters

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1181

SKI Inhibits Primary Cardiac Fibroblast Activation by Initiating LATS2-Hippo Cascade via LIMD1

**Natalie M Landry** , Mark Hnatowich, Thomas W Meier, Simon C Meier, Navid Koleini, Robert R Fandrich, Sunil G Rattan, Elissavet Kardami, Ian M Dixon, Univ of Manitoba, Winnipeg, MB, Canada

1:30 PM

Board # 1182

Mitral Valve Prolapse is Associated With Dysregulated Beta-Catenin Activities

**Lilong Guo** , Katelynn Toomer, Medical Univ of South Carolina, Charleston, SC; Diana Bridget Fulmer, Medical Univ of SC, Charleston, SC; Kelsey Moore, Medical Univ of South Carolin, Charleston, SC; Janiece Glover, Cortney Gensemer, Medical Univ of South Carolina, Charleston, SC; Reece Moore, Goose Creek, SC; Russell A Norris, MEDICAL UNIV OF SOUTH CAROLINA, Charleston, SC

1:30 PM

Board # 1183

PTRH2 Protects the Heart From Pregnancy-Associated Heart Disease

**Michelle L Matter** , Joe W. Ramos, Univ of Hawaii Cancer Ctr, Honolulu, HI

1:30 PM

Board # 1184

Interleukin-1 Beta and Risk of Premature Death in Patients With ST-Segment Elevation Myocardial Infarction

**Johanne Silvain** , Sorbonne Univ - ACTION Coeur Group - Pitie-Salpetriere Hosp (APHP) - INSERM U1166 ICAN, Paris, France; Mathieu Kerneis, Sorbonne Univ - ACTION Coeur Group - Pitie-Salpetriere Hosp (APHP) - INSERM U1166 ICAN, Paris, France, Paris, France; Michel Zeitouni, Duke Clinical Res Inst, Durham, NC; Benoit Lattuca, Sophie GALIER, Sorbonne Univ - ACTION Coeur Group - Pitie-Salpetriere Hosp (APHP) - INSERM U1166 ICAN, Paris, France; delphine brugier, Action-Coeur, PARIS, France; Eric Frisdal, inserm 1166, Paris, France; Wilfried Le Goff, INSERM 1166, Paris, France; Jean Philippe Collet Jr., Sorbonne Univ - ACTION Study Group - APHP- INSERM 1166 ICAN, Paris, France; Eric VICAUT, Sorbonne Univ - ACTION Study Group - APHP- INSERM 1166 ICAN, Paris, France, PARIS, France; Philippe Lesnik, inserm, Paris, France; Gilles Montalescot, SOrbonne Univ - ACTION Coeur s- HOPITAL PITIE SALPETRIERE INSERM 1166, Paris, France; Maryse Guerin, INSERM

1:30 PM

Board # 1185

Mitochondrial ROS Causes Ventricular Ectopy in a Mouse Model of Hypertrophic Cardiomyopathy

**Shan S Parikh** , Vanderbilt Univ, Nashville, TN; Michael Kohlhaas, Comprehensive Heart Failure Ctr, Wuerzburg, Germany; Raghav Venkataraman, Vanderbilt Univ, Nashville, TN; Olga Otto, Dept of Translational Res, Würzburg, Germany; Franz J Baudenbacher, Vanderbilt Univ, Nashville, TN; Christoph Maack, Comprehensive Heart Failure Ctr, Wuerzburg, Germany; Bjorn C Knollmann, VANDERBILT UNIVERSITY, Nashville, TN

1:30 PM

Board # 1186

Unmasking Hidden Hubs of Reentry Driving Persistent Atrial Fibrillation Through Challenge of Driver Physiology

**Brian J Hansen** , THE OHIO STATE UNIVERSITY, Columbus, OH; Katelynn M Helfrich, Ms., Pataskala, OH; Jichao ZHAO, UNIVERSITY OF AUCKLAND, Auckland; Ning LI, The Ohio State Univ, Columbus, OH; Nicholas Salgia, Mustafa M Houmsse, Alexander Iancau, Alexander Zolotarev, THE OHIO STATE UNIVERSITY, Columbus, OH; Dmitry Dylov, Skolkovo Inst of Science and Technology, Moscow, Russian Federation; Stanislav Zakharkin, Solae, Saint Louis, MO; Anuradha Kalyanasundaram, OHIO STATE UNIVERSITY, Columbus, OH; Esthela Artiga, THE OHIO STATE UNIVERSITY, Columbus, OH; Omar Kahaly, THE OHIO STATE UNIVERSITY, Columbus, OH, Columbus, OH; Paul M Janssen, THE OHIO STATE UNIVERSITY, Columbus, OH, Columbus, OH, Columbus, OH; Peter J Mohler, THE OHIO STATE UNIVERSITY MED CTR, Columbus, OH; Nahush Mokadam, Bryan Whitson, The Ohio State Univ, Columbus, OH; Muhammad R Afzal, Orlando Simonetti, THE OHIO STATE UNIVERSITY, Columbus, OH; John Hummel, OSU, Columbus, OH; Vadim V Fedorov, The Ohio State Univ, Columbus, OH

1:30 PM

Board # 1187

Protease Activity is Essential for the Proatherogenic Effects of ADAMTS7

**Taiji Mizoguchi** , Broad Inst, Cambridge, MA; Bryan Macdonald, Broad Inst of MIT and Harvard, Cambridge, MA; Alessandro Arduini, Nicholas Popp, Daniel Lai, Broad Inst, Cambridge, MA; Qiuyu Martin Zhu, MASSACHUSETTS GENERAL HOSPITAL, Cambridge, MA; Patrick Thomas Ellinor, Massachusetts General Hosp, Boston, MA; Sekar Kathiresan, Verve Therapeutics, Cambridge, MA

1:30 PM

Board # 1188

**Ablation of the lncRNA** Airn **Leads to Cardiac Dysfunction**

Giuseppe Militello, UNIVERSITY OF LOUISVILLE, Louisville, KY; Tyler Weirick, CARDIOVASCULAR INNOVATION INSTITUTE, Louisville, KY; Kenneth Brittian, Sujith Dassanayaka, Univ of Louisville, Louisville, KY; Anna Gumpert, Joseph Brady Moore IV, UNIVERSITY OF LOUISVILLE, Louisville, KY; Steven P Jones, UNIVERSITY LOUISVILLE, Louisville, KY; **Shizuka Uchida** , UNIVERSITY OF LOUISVILLE, Louisville, KY

1:30 PM

Board # 1189

The Aptamer BC 007 for the Treatment of Dilated Cardiomyopathy Positive of Autoantibodies Directed Against the β1-Adrenergic Receptor: Evaluation of Safety, Efficacy and Survival in Doberman Pinschers

**Niels-Peter Becker** , Berlin Cures GmbH, Berlin, Germany; Sabine Werner, Clinic of Small Animal Med, LMU Munich, München, Germany; Gerd Wallukat, Katrin Wenzel, Berlin Cures GmbH, Berlin, Germany; Johannes Mueller, Berlin Cures, Berlin, Germany; Gerhard Wess, Clinic of Small Animal Med, LMU Munich, München, Germany; Ingolf Schimke, Berlin Cures GmbH, Berlin, Germany

1:30 PM

Board # 1190

Activation of Type I Interferon Signaling Breaks Mitochondrial Bioenergetics and Drives Lethal Cardiomyopathy

**Manju Kumari** , Evangelakos Ioannis, Tian Tian, Univ Medical Ctr Hamburg-Eppendorf, Hamburg, Germany; Ashraf Y Rangrez, UNIVERSITY MEDICAL CENTER KIEL, Kiel; Anushka Deshpande, Univ Medical Ctr Kiel, Kiel, Germany; Ludger Scheja, Univ Medical Ctr Hamburg-Eppendorf, Hamburg, Germany; Evan Rosen, BIDMC, Harvard Medical Sch, Boston, MA; Joerg Heeren, Univ Medical Ctr Hamburg E, Hamburg, Germany

1:30 PM

Board # 1191

The Longest Paced or Sensed Conduction Time to Determine Optimal Pacing Site During Cardiac Resynchronization Therapy: Results From the Pased CRT Trial

**Raffaele Corbisiero** , Deborah Heart and Lung Ctr, Millstone twsp, NJ; Pedram Kazemian, DEBORAH HEART AND LUNG CENTER, Browns Mills, NJ; JoEllen Schmidt, Deborah Heart and Lung Ctr, Browns Mills, NJ; David R Muller, SJM, SICKLERVILLE, NJ; Sanjay Lloyd Sookhu, SJM, SICKLERVILLE, NJ, Teaneck, NJ; Meet Shah, Deborah Heart, Browns Mills, NJ

1:30 PM

Board # 1194

Addition of Propranolol in Resistant Arterial Hypertension Treatment (APROPRIATE Study) - A Randomized, Double Blinded, Placebo Controlled Clinical Trial

**Godwin R Constantine** , Praveen N tunga, Harshani Ranasinghe, Priyanga Ranasinghe, Univ of Colombo, Colombo-8, Sri Lanka; Rayno Naninan, Sepalika Mendis, Inst of Cardiology, Natl Hosp of Sri Lanka, Colombo-8, Sri Lanka; Chamari Weeraratne, Priyadarshani Galappatthy, Senaka Rajapakse, Upul Senarath, Prasad Katulanda, Univ of Colombo, Colombo-8, Sri Lanka

1:30 PM

Board # 1195

βARKct-Engineered Cellular Exosomes Enhances Targeted Cardio Protection Against Catecholamine-Induced Toxicity versus Non-βARKct Containing Exosomes but Both Are Equally Effective in Protecting Ischemic Myocardial Damage

**Jin-Sook Kwon** , Lewis Katz Sch of Med at Temple Univ, Philadelphia, PA; Sarah M Schumacher, Cleveland Clinic, Cleveland, OH; Erhe Gao, Lewis Katz Sch of Med at Temple Uni, Philadelphia, PA; jessica Ibetti, Lewis Katz Sch of Med at Temple Univ, PHILADELPHIA, PA; Rajika Roy, Lewis Katz Sch of Med at Temple Univ, Philadelphia, PA; Mohsin Khan, Temple Univ, Philadelphia, PA; Raj Kishore, TEMPLE UNIVERSITY SCHOOL OF MED, Philadelphia, PA; Walter J Koch, TEMPLE UNIVERSITY SCHOOL MEDIC, Philadelphia, PA

1:30 PM

Board # 1196

IL-33-Induced Myocardial Eosinophilia Exacerbates Cardiac Remodeling Post-Myocardial Infarction

**Rana Ghali** , Inserm, Unit 970, Paris Cardiovascular Res Ctr, Paris, France; Abdullah Kaplan, Nada Habeichi, Cynthia Tannous, Emna Abidi, American Univ of Beirut, Beirut, Lebanon; Fouad Zouein, American Univ of Beirut, beirut, Lebanon; Ziad Mallat, Cambridge Univ, Cambridge, United Kingdom

1:30 PM

Board # 1197

Resistin Loss Mitigates High-Fat Diet (HFD)-Induced Cardiac Dysfunction

**Ravinder K Kaundal** , Rajvir Singh, Icahn Sch of Med at Mount Sinai, NY, NY; Baoyin Zhao, Icahn Sch of Med at Mount Sinai, NY, CT; Rihab Bouchareb, Icahn Sch of Med at Mount Sinai, NY, NY; Djamel Lebeche, MOUNT SINAI SCHOOL OF MEDICINE, New York, NY

1:30 PM

Board # 1198

Discovery of s Cardiac Role for a "Neuronal Protein", Reduced Levels of Disrupted in Schizophrenia 1 (DISC1) in the Heart Causes Cardiac Deterioration and Mitochondrial Dysfunction

Maria J Pinho, Nathan R Scrimgeour, Mathias Nyman, Faculty of Med, NTNU, Trondheim, Norway; Francisco J Enguita, 2Insto de Medicina Molecular, Faculty of Med, Univ of Lisbon, 1649-028 Lisboa, Portugal, Lisbon, Portugal; Koko Ishizuka, Johns Hopkins Univ Sch of Med, Baltimore, MD, Baltimore, MD; Akira Sawa, Johns Hopkins Univ Sch of Med, Baltimore, MD, baltimore, MD; **Morten A Hoydal** , Faculty of Med, NTNU, Trondheim, Norway

1:30 PM

Board # 1199

Neoadjuvant Chemotherapy Induces Vascular Dysfunction and Hypertension Through Nox4 Dependent Mechanism

**Piotr Szczepaniak** , Mateusz Siedlinski, Diana Hodorowicz-Zaniewska, Jagiellonian Univ Medical Coll, Krakow, Poland; Ryszard Nosalski, Univ of Glasgow, Glasgow, United Kingdom; Anna Dikalova, Sergey I Dikalov, Vanderbilt Univ Medical Ctr, Nashville, TN; Joanna Streb, Katarzyna Gara, Pawel Basta, Jaroslaw Krolczyk, Joanna Sulicka, Tomasz Mikolajczyk, Jagiellonian Univ Medical Coll, Krakow, Poland; Anna Dziewulska, Anna Dobosz, Nencki Inst of Experimental Biology, Warsaw, Poland; Ewelina Jozefczuk, Jagiellonian Univ Medical Coll, Krakow, Poland; Pasquale Maffia, Univ of Glasgow, Glasgow, United Kingdom; Marta Czesnikiewicz-Guzik, Jagiellonian Univ Medical Coll, Cracow, Poland; Agnieszka Dobrzyn, Nencki Inst of Experimental Biology, Warsaw, Poland; Javid Moslehi, David Harrison, Vanderbilt Univ Medical Ctr, Nashville, TN; Tomasz Grodzicki, Jagiellonian Univ Medical Coll, Krakow, Poland; Tomasz Guzik, Univ of Glasgow, Glasgow, United Kingdom

1:30 PM

Board # 1200

Pharmacological Inhibition of PAI-1 Alleviates Cardiopulmonary Pathologies Induced by Short-Term Exposure to Air-Pollutants

**Asish K Ghosh** , Saul Soberanes, Elizabeth Lux, Mesut Eren, E. Scott Budinger, NORTHWESTERN UNIVERSITY, Chicago, IL; Toshio Miyata, Tohoku Univ, Miyagi, Japan; Douglas E Vaughan, NORTHWESTERN UNIVERSITY, Chicago, IL

1:30 PM

Board # 1201

Developing Optimal Phenotype Algorithms of Serum Lipid Levels in Electronic Health Records for Genetic Analysis in Large-Scale Biobanks

**Hung-Hsin Chen** , Vanderbilt Univ, Nashville, TN; Eric R. Gamazon, Vanderbilt Univ Medical Ctr, Nashville, TN; Quinn Wells, Jennifer Below, VANDERBILT UNIVERSITY, Nashville, TN

1:30 PM

Board # 1202

Branched Chain Amino Acid Induced Cardiac Hypertrophy is Time-of-Day Dependent

**Mary N Latimer** , Sobuj Mia, UNIVERSITY OF ALABAMA BIRMINGHAM, Birmingham, AL; Martin E Young, UNIVERSITY ALABAMA BIRMINGHAM, Birmingham, AL

1:30 PM

Board # 1203

Critical Role of Stress-Response C-Jun N-Terminal Kinase in Inflammatory Bowel Disease-Associated Atrial Fibrillation

**Elena Carrillo** , Jiajie Yan, Weiwei Zhao, Jesus Leonardo Rondon, Rush Univ Medical Ctr, Chicago, IL; Le Shen, The Univ of Chicago, Chicago, IL; Xun Ai, Rush university medical center, Chicago, IL

1:30 PM

Board # 1204

A Novel Murine Model to Study Postnatal Coronary Collateral Growth by Lineage Tracing

**Anurag Jamaiyar** , Northeast Ohio Medical Univ, Rootstown, OH; Cody Juguilon, Northeast Ohio Medical Univ, Rootstowan, OH; Devan Richardson, James Gadd, Tao Wang, Northeast Ohio Medical Univ, Rootstown, OH; Molly Enrick, NEOMED, Rootstown, OH; William M Chilian, NORTHEAST OHIO MEDICAL UNIV, Rootstown, OH; Liya Yin, NORTHEAST OHIO MEDICAL UNIVERSITY, Rootstown, OH

1:30 PM

Board # 1205

Upregulation of Long Non-Coding RNA CISAT in Human Cardiac Progenitor Cells Promotes Their Capacity for Myocardial Repair

Xiuchun Li, Xiao-Liang Wang, The Ohio State Univ, Columbus, OH; Edward Bennett, Albany Medical Coll, Albany, NY; Nahush Mokadam, Jianjie Ma, **Chuanxi Cai** , The Ohio State Univ, Columbus, OH

1:30 PM

Board # 1206

Alternative Protein Isoforms in the Aging and Diseased Hearts

Erin Yu Han, Univ of Colorado Denver, Aurora, CO; Rushita A Bagchi, UNIVERSITY OF COLORADO DENVER, Aurora, CO; Julianna Wright, Univ of Colorado Denver, Aurora, CO; Edward Lau, STANFORD UNIVERSITY, Palo Alto, CA; **Maggie Py Lam** , Univ of Colorado Denver, Aurora, CO

1:30 PM

Board # 1207

The Variation Coefficient of the Seventh Harmonic Amplitude of the Radial Pulse Wave Predicts the Risk of Cerebrovascular Disease and Dementia in Patients With Type 2 Diabetes

**Chi-wei Chang** , Mii-Ann Medical Ctr, Taipei, Taiwan; kuomeng Liao, taipei; Yi-Ting Chang, taipei, Rockville, MD; Sheng-Hung Wang, taipei, Rockville, MD, Taipei; Ying-Chun Chen, Zhongxiao Branch of Taipei City Hosp, Taipei, Taiwan; gin-chung wang, Zhongxiao Branch of Taipei City Hosp, Taipei, Taiwan, Lincolnshire, IL

1:30 PM

Board # 1208

Prophylactic Inhibition of Atgl During Myocardial Infarction Yields Lasting Improvements in Cardiac Function

Katharina Bottermann, **Mitchell E Granade** , Univ of Virginia, Charlottesville, VA; Vici Oenarto, Heinrich Heine Univ, Dusseldorf, Germany; Thurl Harris, UNIVERSITY OF VIRGINIA, Charlottesvle, VA

1:30 PM

Board # 1209

Novel Use of DESI-MS on Cardiac Tissue for the Metabolic Characterization of Atrial Fibrillation

Gianluigi Bisleri, **Syed M Ali Hassan** , Diane Tomalty, Martin Kaufmann, Kevin Yi Mi Ren, Randy Ellis, Queen's Univ, Kingston, ON, Canada

1:30 PM

Board # 1210

Hypertension Causes Osteoporosis and Bone Marrow Activation

**Luciana Do Carmo** , Vanderbilt, Nashville, TN; Liang Xiao, Liang Xiao, Nashville, TN; Sasidhar Uppuganti, David Florian, Jeffry Nyman, Scott Guelcher, David G Harrison, Vanderbilt, Nashville, TN

1:30 PM

Board # 1211

Legacy of Lipid Lowering in Preventing Fatal and Non Fatal Cardiovascular Events in Individuals Without Cardiovascular Disease During 3 Years of Post Trial Observation in the HOPE 3 (Heart Outcomes Prevention Evaluation) Study

**Jackie Bosch** , MCMASTER UNIVERSITY, Hamilton, ON, Canada; Eva M Lonn, Hyejung Jung, HAMILTON GENERAL HOSP, Hamilton, ON, Canada; Salim Yusuf, POPULATION HEALTH RESEARCH INSTITUT, Hamilton, ON, Canada; HOPE-3 Investigators

# Abstract Poster Session

## AT.APS.03 - Lipid Lowering and the Origins of Cardiovascular Disease

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1044

A Novel Approach For Uric Acid Crystal Detection in Human Coronary Plaques Ex-Vivo With Cross-Polarized Micro-OCT

**Kensuke Nishimiya** , Gargi Sharma, Kanwarpal Singh, Joseph A Gardecki, Tearney J Guillermo, Harvard Medical Sch, Massachusetts General Hosp, Boston, MA

1:30 PM

Board # 1045

Air Pollution Associates With Leukopoietic Activity: A Link to Atherosclerotic Inflammation

**Shady Abohashem** , Tawseef Dar, Azar Radfar, Massachusetts General Hosp-Harvard medical school, Boston, MA; Brian Tung, Blake Oberfeld, Nicki Naddaf, Tomas Patrich, Ahmed Ghoneem, Parastou Ghazi, James Jaffer, Massachusetts General Hosp, Boston, MA; Michael T. Osborne, Ahmed A Tawakol, Massachusetts General Hosp-Harvard medical school, Boston, MA

1:30 PM

Board # 1046

Lipoprotein(a), Oxidized Phospholipids and Cardiovascular Risk: Relation to Ethnicity, Age and Family Structure

**Enkhmaa Byambaa** , Univ of California Davis, Davis, CA; Anuurad Erdembileg, UC Davis, Sacramento, CA; Wei Zhang, Univ of California Davis, Davis, CA; Lars Berglund, UC Davis, Sacramento, CA

1:30 PM

Board # 1047

Free Fatty Acids and Myocardial Infarction, Coronary Heart Disease, Cardiovascular Disease

Sarah O Nomura, Amy B Karger, **Natalie L Weir** , Michael Y Tsai, Univ of Minnesota, Minneapolis, MN

1:30 PM

Board # 1049

Exploring the Causal Pathway From Omega-6 Levels to Coronary Heart Disease: A Network Mendelian Randomization Study

**Xiaodong Zhuang** , First Affiliated Hosp, Sun Yat-Sen Univ, Guangzhou, China; Lizhen Liao, Guangdong Pharmaceutical Univ, Guangzhou, China; Xinxue Liao, First Affiliated Hosp, Sun Yat-Sen Univ, guangzhou, China

1:30 PM

Board # 1050

The Potential Role for YIAS1 in Initiation and Progression of Atherosclerosis

Jian Fu, **Ying Jin** , Hubei Univ of Med Renmin Hosp, ShiYan, China

1:30 PM

Board # 1051

Global Knockout of LDLRAP1 Regulates Atherosclerosis, Insulin Resistance, and VSMC Foam Cell Formation

**Tani Leigh** , Sheri Kelemen, Mitali Ray, Christine Vrakas, Allison Herman, Gavin Landesberg, Rachael Okune, Rosario Scalia, Michael Autieri, Lewis Katz Sch of Med at Temple Univ, Philadelphia, PA

1:30 PM

Board # 1052

LEGACY: Phase 2a Trial to Evaluate the Safety, Pharmacokinetics and Pharmacodynamic Effects of the Anti-Endothelial Lipase Antibody MEDI5884 in Subjects With Stable CAD

**Christian T Ruff** , Brigham Women's Hosp, Boston, MA; Joe S Grimsby, Medimmune, Gaithersburg, MD; Anton Rosenbaum, ChaoYu Jin, Lan-Feng Tsai, AstraZeneca, Wilmington, DE; Sotirios Karathanasis, Medimmune, Rockville, MD; Judith Falloon, Tim Hummer, Xiao Tu, AstraZeneca, Wilmington, DE; Judith A Hsia, MedImmune, McLean, VA; Boaz Hirshberg, Medimmune, Gaithersburg, MD; Michael J Koren, Jacksonville Ctr for Clinical Res, Jacksonville, FL; Marc S Sabatine, TIMI Study Group, Boston, MA

1:30 PM

Board # 1053

Cell-Free HDL-Specific Phospholipid Efflux Predicts Plaque Burden and Coronary Artery Disease

**Edward Bryan Neufeld** , Masaki Sato, NHLBI NIH, Bethesda, MD; Martin P Playford, Natl Insts of Health, NHLBI, Bethesda, MD; Alexander V Sorokin, NHLBI NIH, Bethesda, MD; Angel Aponte, NHLBI, NIH, Bethesda, MD; Scott M Gordon, Univ of Kentucky, Lexington, KY; Nehal N Mehta, NIH, Bethesda, MD; Marcus Chen, NIH, NHLBI, MD; Alan T Remaley, NHLBI NIH, Bethesda, MD

# Abstract Poster Session

## AT.APS.04 - Lipid-Mediated Mechanisms Contributing to Atherogenesis

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1054

Ketogenesis Protects Mitochondrial Function by Modulating Post-Translational Modification

**Yuichiro Arima** , Toshifumi Ishida, Kumamoto Univ, Kumamoto, Japan; Taishi Nakamura, Kumamoto Univ Hosp, Kumamoto, Japan; Satoshi Araki, Eiichiro Yamamoto, Kumamoto Univ, Kumamoto, Japan; Kenji Sakamoto, Kumamoto Univ Hosp, Kumamoto, Japan; Koichi Kaikita, Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

1:30 PM

Board # 1055

SDPR/Cavin-2 Regulates Adipocyte Differentiation With Suppression of PPARγ and C/EBPα Expressions in 3T3L1 Cells

**Yusuke Higuchi** , Takehiro Ogata, Akira Sakamoto, Naohiko Nakanishi, Yumika Tsuji, Shinya Tomita, Satoaki Matoba, Kyoto Prefectural Univ of Med, Kyoto, Japan

1:30 PM

Board # 1056

Purified Eicosapentaenoic Acid Ameliorates Cardiac Fibrosis and Tissue Inflammation in Spontaneously Hypertensive Rats

**Giselle C Melendez** , Wake Forest Baptist Health, Winston Salem, NC; Danielle Medina-Hernandez, Wake Forest Sch of Med, Winston Salem, NC; Adam W Pflum, Wake Forest Univ, Clemmons, NC; Vivian Xu, Wake Forest Sch of Med, Winston Salem, NC; David M Herrington, Wake Forest Univ Sch Med, Winston Salem, NC

1:30 PM

Board # 1057

Epoxigenated Omega-3 Fatty Acid Metabolites Produced by Mast Cells Attenuate Pulmonary Vascular Remodeling

**Hidenori Moriyama** , Jin Endo, Masaharu Kataoka, Motoaki Sano, Keiichi Fukuda, Keio Univ Sch of Med, Tokyo, Japan

1:30 PM

Board # 1058

Insulin and Neuropilin-1 Interaction Promote Insulin Resistance

**Imoh Okon** , Ming-Hui Zou, Sean Carr, Ramprasath Tharmarajan, Georgia State Univ, Atlanta, GA

1:30 PM

Board # 1059

Impairment of Pla2g6 in Smooth Muscle Protects Against Arterial Stiffening Without Parkinson Disease

Kerrie Lahoda, Abdullah Hijazi, **Joon W Shim** , Marshall Univ, Huntington, WV

1:30 PM

Board # 1060

C-Type Natriuretic Peptide (CNP) Regulates Adipogenesis, Thermogenesis and Glucose Sensitivity via Natriuretic Peptide Receptor (NPR)-C Signalling

**Cristina Perez-Ternero** , Aisah A Aubdool, Amie J Moyes, Adrian J Hobbs, Queen Mary Univ of London, London, United Kingdom

1:30 PM

Board # 1061

Over Expression of the Insulin Like Growth Factor Type 1 Receptors in Endothelial Cells Protects Against the Development of Obesity

**Natalie Haywood** , Univ of Leeds, Leeds, United Kingdom; Katherine Bridge, Univ of Leeds, Leeds; Nele Warmke, Michael Drozd, Lee Roberts, Natallia Makava, Anna Skromna, Univ of Leeds, Leeds, United Kingdom; Nadira Y Yuldasheva, Univ Of Leeds, Leeds, United Kingdom; Stephen B Wheatcroft, Univ Leeds, Leeds, United Kingdom; Richard Cubbon, The Univ of Leeds, Leeds; Mark Kearney, Univ of Leeds, Leeds

1:30 PM

Board # 1063

Sex Dependent Role of Atrial Natriuretic Peptide in the Regulation of Blood Pressure in Prostaglandin Deficient Mice

**Soon Yew Tang** , Sean Anderson, Hu Meng, Dimitra Sarantopoulou, Emanuela Ricciotti, Elizabeth J Hennessy, Gregory R Grant, Garret A Fitzgerald, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Poster Professor

Alison B Kohan, Storrs, CT

1:30 PM

Board # 1064

The Natural Flavone Acacetinslows the Development of Atherosclerosis by Sirt3-Mediated Activation of AMPK Signaling Pathway in Diabetic ApoE Null Mice

**Wei-Min Han** , Xu-Chang Chen, Yi-Xiang Hong, Hui-Min Wang, Gui-Rong Li, Yan Wang, Xiamen Cardiovascular Hosp, Xiamen, China

1:30 PM

Board # 1065

PCSK9 Inhibitors, an Ineffectual Treatment for Apolipoprotein B-100 Defective Familial Hypercholesterolemia

Michael Dee Holyoak, Lauryn K Gorby, **Patrick Maurice Moriarty** , Univ of Kansas Medical Ctr, Kansas City, KS

# Abstract Poster Session

## EP.APS.01 - Lipids and CV Prevention: Is There More to it Beyond LDL Lowering?

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3033

Utility of Non-hdl-c and Apob Targets at Progressively Lower Ldl-c Down to Levels Less Than 40 Mg/dl

**Vasanth Sathiyakumar** , Johns Hopkins Hosp, Baltimore, MD; Jihwan Park, Aparna Sajja, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Eliseo Guallar, Mariana Lazo, Steven R Jones, Seth S Martin, Johns Hopkins Univ, Baltimore, MD

1:30 PM

Board # 3035

Modern Prevalence of Fredrickson-Levy-Lees Type III Hyperlipoproteinemia: Findings From the Very Large Database of Lipids and National Health and Nutrition Examination Survey

**Vincent A Pallazola** , Johns Hopkins Univ, Baltimore, MD; Vasanth Sathiyakumar, Johns Hopkins Hosp, Baltimore, MD; Jihwan Park, Johns Hopkins Univ, Baltimore, MD; Rachit Vakil, Johns Hopkins Hosp, Baltimore, MD; Peter P Toth, CGH Medical Ctr, Coleta, IL; Mariana Lazo-Elizondo, Emily Brown, Johns Hopkins Univ, Baltimore, MD; Renato Quispe, Johns Hopkins Ciccarone Ctr, Bronx, NY; Eliseo Guallar, Johns Hopkins Univ, Baltimore, MD; Roger S Blumenthal, Johns Hopkins Hosp, Baltimore, MD; Steven R Jones, Johns Hopkins Univ, Baltimore, MD; David Marais, Univ of Cape Town Health Sciences, Cape Town, South Africa; Daniel Soffer, Univ of Pennsylvania Perelman Sch of Med, Philadelphia, PA; Allan D Sniderman, Royal Victoria Hosp, Montreal, QC, Canada; Seth S Martin, Johns Hopkins Hosp, Baltimore, MD

1:30 PM

Board # 3036

Real-World Risk of Cardiovascular Outcomes Associated With Hypertriglyceridemia Among Individuals With Atherosclerotic Cardiovascular Disease and Potential Eligibility for Emerging Therapies

**Patrick R Lawler** , Peter Munk Cardiac Ctr, Toronto, ON, Canada; Gynter Kotrri, Univ of Toronto Sch of Med, Toronto, ON, Canada; Maria Koh, Inst for Clin. Eval. Sciences, Toronto, ON, Canada; Shaun Geoffrey Goodman, St Michaels Hosp, Toronto, ON, Canada; Michael E Farkouh, Peter Munk Cardiac Ctr, Toronto, ON, Canada; Douglas Lee, Inst for Clin. Eval. Sciences, Toronto, ON, Canada; Peter Austin, Inst for Clinical Evaluative S, Toronto, ON, Canada; Jacob A Udell, Women's Coll Hosp, Univ of Toronto, Toronto, ON, Canada; Dennis T Ko, ICES, Toronto, ON, Canada

1:30 PM

Board # 3037

Incidence Rates of Severe Hypertriglyceridemia in Olmsted County, Minnesota: A Population-Based Study

**Harigopal Sandhyavenu** , Ahmed Pasha, Medhat Farwati, Kent Bailey, Mayo Clinic, Rochester, MN; Umama Gorsi, Mayo Clinic, Endicott, NY; Carin Smith, Christina Wood-Wentz, Iftikhar J Kullo, Mayo Clinic, Rochester, MN

1:30 PM

Board # 3038

Small Dense Low Density Lipoprotein Cholesterol Level Predicts Carotid Intimal Medial Thickness Progression

**Hiroaki Ikezaki** , HNRCA at Tufts Univ, Boston, MA; Norihiro Furusyo, Kyushu Univ Hosp, Fukuoka, Japan; Yuya Yokota, Showa Univ Sch of Med, Tokyo, Japan; Masumi Ai, Tokyo Medical And Dental Univ, Wako (Saitama-pref), Japan; Bela F Asztalos, Tufts Univ, Boston, MA; Masayuki Murata, Jun Hayashi, Kyushu Univ Hosp, Fukuoka, Japan; Ernst J Schaefer, Tufts Univ, Boston, MA

1:30 PM

Board # 3039

LDL Particle Size is a Predictor of Cardiovascular Events in Cardiovascular Disease Patients With Nonalcoholic Fatty Liver Disease as Well as in Those Without Nonalcoholic Fatty Liver Disease

Andreas Leiherer, Axel Muendlein, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; **Christoph H Saely** , Private Univ of the Principality of Liechtenstein, Triesen, Liechtenstein; Alexander Vonbank, Arthur Mader, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Joern F Dopheide, Iris Baumgartner, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland; Peter Fraunberger, Medical Central Labs, Feldkirch, Austria; Heinz Drexel, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland

1:30 PM

Board # 3040

Triglycerides Predict Decline in Renal Function Independently of Blood Pressure and Other Cardiovascular Risk Factors in the Multi-ethnic Study of Atherosclerosis

**Daniel A Duprez** , Univ of Minnesota, Minneapolis, MN; Joachim H Ix, Univ of California San Diego, La Jolla, CA; Carmen Peralta, SFVA Medical Ctr, San Francisco, CA; Jorge Kizer, San Francisco VA Health Care System, San Francisco, CA; Steven Shea, Columbia Univ, New York, NY; David Jacobs, Univ of Minnesota, Minneapolis, MN

1:30 PM

Board # 3041

Modern Prevalence of Familial Chylomicronemia Syndrome

**Vincent A Pallazola** , Aparna Sajja, Robert Derenbecker, Oluseye Ogunmoroti, Jihwan Park, Johns Hopkins Univ, Baltimore, MD; Vasanth Sathiyakumar, Seth S Martin, Johns Hopkins Hosp, Baltimore, MD

1:30 PM

Poster Professor

Anand Rohatgi, Dallas, TX

1:30 PM

Board # 3042

New Found Risk Factor for Limited Effect of Second Generation Drug Eluting Stent in Diabetic Patients: Triglyceride Deposit Cardiomyovasculopathy, a Novel Type Atherosclerosis With Triglyceride Deposition

Yusuke Nakano, **Atomu Tajima** , Aichi Medical Univ, Nagakute, Japan; Hirofumi Ohashi, Aichi Medical Univ, Aichi, Japan; Masahiro Shimoda, Hirokazu Wakabayashi, Aichi Medical Univ, Nagakute, Japan; Hirohiko Ando, Aichi Medical Univ, Aichi, Japan; Katsuhisa Waseda, Hiroaki Takashima, Aichi Medical Univ, Nagakute, Japan; Ken-ichi Hirano, Osaka Univ, Suita, Osaka, Japan; Tetsuya Amano, Aichi Medical Univ, Nagakute, Japan

# Abstract Poster Session

## HF.APS.01 - Management of Pericarditis

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2046

Association of Autoimmune Diseases in Patients Presenting With Pericardial Diseases

**Yasser Al-Khadra** , Cleveland Clinic Fndn, Cleveland, OH; Fahed Darmoch, Beth Israel Deaconess Medical, Somerville, MA; Ziad SayedAhmad, Beaumont Hosp, Royal Oak, MI; Homam Moussa Pacha, Univ of Texas Health Science Ctr, McGovern Medical Sch, Memorial Hermann Heart & Vascular Inst, Arlington, VA; Mohamad Soud, MedStar Washington Hosp Ctr, Washington, DC; Massimo Imazio, Ospedale Maria Vittoria Hos, Torino, Italy; Allan L Klein, Cleveland Clinic, Cleveland, OH; M Chadi M Alraies, Wayne State Univ - DMC, Detroit, MI

1:30 PM

Board # 2047

Acute Right Ventricular Failure Following Therapeutic Pericardiocentesis for Cardiac Tamponade

**Kassra Poosti** , Univ of California San Francisco Fresno Medical Education Program, Fresno, CA

1:30 PM

Board # 2048

In-Hospital Outcomes of Acute Pericarditis Patients With and Without Autoimmune Disease

**Yasser Al-khadra** , Cleveland Clinic Fndn, Cleveland, OH; Fahed Darmoch, Beth Israel Deaconess Medical, Somerville, MA; Ziad SayedAhmad, Beaumont Hosp, Royal Oak, MI; Homam Moussa Pacha, Univ of Texas Health Science Ctr, McGovern Medical Sch, Memorial Hermann Heart & Vascular Inst, Arlington, VA; Mohamad Soud, MedStar Washington Hosp Ctr, Washington, DC; Massimo Imazio, Ospedale Maria Vittoria Hos, Torino, Italy; Allan L Klein, Cleveland Clinic, Cleveland, OH; M Chadi M Alraies, Wayne State Univ - DMC, Detroit, MI

1:30 PM

Board # 2049

Predictors of Adverse Outcomes in Patients With Acute Pericarditis

**Alessandra Vecchie** , Virginia Commonwealth Univ Hosp, Richmond, VA; Juan Guido Chiabrando, Hosp Italiano de Buenos Aires, Buenos Aires, Argentina; Megan Dell, Virginia Commonwealth Univ Hosp, Richmond, VA; George Wohlford, Virginia Commonwealth Univ, Richmond, VA; Sherrie Tafuri, John Paolini, Kiniksa Pharmaceuticals, Bermuda, Bermuda; Benjamin W Van Tassell, Virginia Commonwealth Univ Hosp, Richmond, VA; Anna Beutler, Kiniksa Pharmaceuticals, Bermuda, Bermuda; Tamas Gal, Virginia Commonwealth Univ Hosp, Richmond, VA; Fabrizio Montecucco, Univ of Genoa, Genoa, Italy; Antonio Abbate, Virginia Commonwealth Univ Hosp, Richmond, VA

1:30 PM

Board # 2050

A Novel Marker of Constrictive Physiology in Biventricular Heart Failure: Discordance of Aortic and Pulmonary Artery Pulse Pressure Area-Under-the-Curve Demonstrating Interventricular Dependence

**Siu-Hin Wan** , Joshua Vogt, Mayo Clinic, Rochester, MN; Rick A Nishimura, Mayo Clinic Rochester, Rochester, MN

1:30 PM

Board # 2051

In-Hospital Outcomes of Pericardiocentesis versus Pericardial Surgical Interventions: A Population-Based Cohort

**Mohamed M Gad** , Cleveland Clinic, Cleveland, OH; Islam Y Elgendy, Massachusetts General Hosp, Boston, MA; Ahmed N Mahmoud, Univ of Washington, Seattle, WA; Ayman Elbadawi, Rochester General Hosp, Rochester, NY; Toug Tanavin, Baylor Sch of Med, Houston, TX; Ali E Denktas, Baylor Coll of Med, Houston, TX; Ernest Jimenez, Baylor Sch of Med, Houston, TX; Samir R Kapadia, Cleveland Clinic, Cleveland, OH; Hani Jneid, Baylor Coll of Med, Houston, TX

1:30 PM

Board # 2052

Causes and Predictors of 30-Day Readmissions in Patients With Acute Pericarditis: A Nationwide Cohort Study

**Yasser Al-khadra** , Cleveland Clinic Fndn, Cleveland, OH; Marvin Kajy, Wayne State Univ, Detroit Medical Ctr, Detriot, MI; Fahed Darmoch, Beth Israel Deaconess Medical, Somerville, MA; Homam Moussa Pacha, Univ of Texas Health Science Ctr, McGovern Medical Sch, Memorial Hermann Heart & Vascular Inst, Arlington, VA; Mohamad Soud, MedStar Washington Hosp Ctr, Washington, DC; Allan L Klein, Cleveland Clinic, Cleveland, OH; M Chadi M Alraies, Wayne State Univ - DMC, Detroit, MI

1:30 PM

Board # 2053

Misclassification of Pericardial Disease Diagnosis; International Classification of Diseases-10 Coding Requires Validation

**Muhammad Mohsin Furqan** , Cleveland Clinic Fndn, Cleveland, OH; Michael Chetrit, Paul Cremer, Allan L Klein, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 2054

Transient Manifestation Of J-waves By Acute Pericarditis: Abnormalities In Subepicardium Are Possibly Associated With The Genesis Of J-waves

**Taisuke Harada** , Ichitaro Abe, Shintaro kira, Mikiko Nakagawa, Naohiko Takahashi, Oita Univ, Oita, Japan

1:30 PM

Board # 2055

Pericardiocentesis and Pericardiotomy: A National Comparison of Utilization, Cost and Outcomes

**Swiri Konje** , Lingling Wu, Mount Sinai St Luke's and West, New York, NY; Wojciech Rzechorzek, Mount Sinai St. Luke's West, New York, NY; Alba Munoz Estrella, Mount Sinai St Luke's and West Hosp, new york, NY; Eyal Herzog, Mount Sinai St Luke's Hosp, New York, NY

1:30 PM

Poster Professor

Allan L Klein, Cleveland, OH

# Abstract Poster Session

## PH.APS.04 - Markers and Outcomes in Pulmonary Hypertension I

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2241

Predictors of Mortality in Sudden Cardiac Arrest With Chronic Pulmonary Disease Patients, a Logistic Regression on National Inpatient Sample

**Muhammad Zia Khan** , WV Med, Section of Hosp Me, Morgantown, WV; Muhammad Usman Khan, West Virginia Univ, HSC, Morgantown, WV; Muhammad Munir, West Virginia Univ, Sch of Med, Morgantown, WV; Safi Ullah Khan, West Virginia Univ, Morgantown, WV; Ahmad Naeem Lone, Sudarshan Balla, West Virginia Univ, Sch of Med, Morgantown, WV

1:30 PM

Board # 2242

FGF23 Plays a Role in the Development of Post-Splenectomy Cardiovascular Complications in a Thalassemia Murine Model

**Ling Wang** , Jonas Sertorio, Taijyu Satoh, Derek Sinchar, Timothy Bachman, jeffrey J. Baust, Andrea Sebastiani, Scott Hahn, Hongshuai Li, Adam C Straub, Mark T Gladwin, Univ of Pittsburgh, Pittsburgh, PA

1:30 PM

Board # 2243

**Electron Transport Chain Inhibition Induces Mitochondrial Fragmentation and Depolarization in Vascular Smooth Muscle Cells:** Mitochondrial Structure and Function Relationship in Pulmonary Arterial Hypertension

**Kimberly J Dunham-Snary** , François Potus, Queen's Univ, Kingston, ON, Canada; Patricia DA Lima, Queen's CardioPulmonary Unit, Kingston, ON, Canada; Jeffrey D Mewburn, Stephen L Archer, Queen's Univ, Kingston, ON, Canada

1:30 PM

Board # 2244

Unilateral Pulmonary Artery Banding Prevents and Reverses Lung Micro-Vascular Loss in the Rat SU5416-Hypoxia Model of Severe Pulmonary Arterial Hypertension

Yupu Deng, **Ketul R Chaudhary** , Anli Yang, Katelynn Rowe, Duncan J Stewart, Ottawa Hosp Res Inst, Ottawa, ON, Canada

1:30 PM

Board # 2245

Generalized Equation of the Pulmonary Circulation, Implications for Epidemiological and Longitudinal Studies in Pulmonary Hypertension Across Who Groups

**Myriam Amsallem** , Stanford Univ, Stanford, CA; Ryan J Tedford, Medical Univ South Carolina, Charleston, SC; Andre Yvan Denault, Montreal Heart Inst, Montreal, QC, Canada; Andrew Sweat, Stanford Univ, Stanford, CA; Julien Guihaire, Marie Lannelongue Hosp, Le Plessis Robinson, France; Kristofer Hedman, Shadi Peighambari, Brian J. Kim, Xiao Li, Robert Jh Miller, Stanford Univ, Stanford, CA; Olaf Mercier, Elie Fadel, Marie Lannelongue Hosp, Le Plessis Robinson, France; Roham Zamanian, Stanford Univ, Stanford, CA; Francois Haddad, Stanford Univ, Palo Alto, CA

1:30 PM

Board # 2246

Pulmonary Arterial Remodeling is Related to the Risk Stratification Score in Prevalent Pulmonary Arterial Hypertension Patients

Juan C Grignola, Hosp de Clinicas, UdelaR, Montevideo, Uruguay; **Enric Domingo** , Alvaro Calabuig, Santiago Pérez Hoyos, Manuel López Messeguer, Antonio Roman, Hosp Univri Vall d'Hebron, Barcelona, Spain

1:30 PM

Board # 2247

Pulmonary Arterial Hypertension Patients Display Normal Kinetics of Clot Formation

**Mengyun Lu** , Kevin P Blaine, Ann Cullinane, Courtney Hall, Alina Dulau-Florea, Junfeng Sun, Herman Chenwi, Grace Graninger, Bonnie Harper, Jason M Elinoff, Natl Insts of Health Clinical Ctr, Bethesda, MD; Michael A Solomon, Natl Insts of Health, Bethesda, MD

1:30 PM

Board # 2248

Additional Role of Unmodifiable Risk Factors in Pulmonary Arterial Hypertension Risk Stratification According to Current ESC/ERS Guidelines

**Fabio Dardi** , Massimiliano Palazzini, Enrico Gotti, Elisa Zuffa, Alessandro De Lorenzis, Guarino Daniele, Ilenia Magnani, Andrea Rinaldi, Mariangela Rotunno, Alessandra Manes, Nazzareno Galiè, Inst of Cardiology, Univ of Bologna, Bologna, Italy

1:30 PM

Board # 2249

Early Canadian Experience Using Selexipag as Part of an Oral Triple Therapy Regimen in Pediatric Patients With Severe Pulmonary Arterial Hypertension

**Konstantin Averin** , Susan Richards, Stollery Childrens Hosp, Edmonton, AB, Canada; Erika Vorhies, Alberta Children's Hosp, Calgary, AB, Canada; Angela Bates, Stollery Childrens Hosp, Edmonton, AB, Canada

1:30 PM

Board # 2250

Additional Role of Echocardiogram in Pulmonary Arterial Hypertension Risk Stratification According to Current ESC/ERS Guidelines

**Fabio Dardi** , Massimiliano Palazzini, Enrico Gotti, Elisa Zuffa, Daniele Guarino, Filippo Pasca, Alessandro De Lorenzis, Ilenia Magnani, Andrea Rinaldi, Mariangela Rotunno, Alessandra Manes, Nazzareno Galiè, Inst of Cardiology, Univ of Bologna, Bologna, Italy

1:30 PM

Board # 2251

Multimodal Assessment of Right Ventricle Overload -Metabolic and Clinical Consequences in Pulmonary Arterial Hypertension

**Remigiusz Kazimierczyk** , Medical Univ of Bialystok, Bialystok, Poland; Lukasz A Malek, Univ of Physical Education, Warsaw, Poland; Piotr Szumowski, Medical Univ of Bialystok, Bialystok, Poland; Piotr Blaszczak, Wyszynski Hosp, Lublin, Poland; Dorota Jurgilewicz, Marcin Hladunski, Bozena Sobkowicz, Medical Univ of Bialystok, Bialystok, Poland; Janusz Mysliwiec, Medical Univeristy of Bialystok, Bialystok, Poland; Ryszard Grzywna, Wyszynski Hosp, Lublin, Poland; Wlodzimierz Musial, Karol K Kaminski, Medical Univ of Bialystok, Bialystok, Poland

1:30 PM

Board # 2252

Circulating CD271 is Associated With the Severity of Pulmonary Arterial Hypertension

**Chiaki Goten** , Soichiro Usui, Oto Inoue, Kanazawa Univ, Kanazawa, Japan; Shin-Ichiro Takashima, Kanazawa Univ, kanazawa, Japan; Hisayoshi Murai, Masayuki Takamura, Kanazawa Univ, Kanazawa, Japan

1:30 PM

Board # 2253

PBI-4050 Reduces Angio-proliferative Pulmonary Arterial Hypertension: Decreased Human Pulmonary Artery Smooth Muscle Cell Proliferation and Microvascular Endothelial Cell Endoplasmic Reticulum Stress

Mohamed Jalloul Nsaibia, Prometic Biosciences Inc., Laval, QC, Canada; Quang Nguyen, Inst de Cardiologie de Montreal, Montreal, QC, Canada; Lyne Gagnon, Brigitte Grouix, Prometic Biosciences Inc., Laval, QC, Canada; **Jocelyn Dupuis** , Inst de Cardiologie de Montreal, Montreal, QC, Canada

# Abstract Poster Session

## PH.APS.01 - Mechanistic Clinical Biomarkers of PH, HFpEF and RV Dysfunction

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2206

Diagnostic and Prognostic Significance of Serum Levels of Selenoprotein P in Patients With Pulmonary Arterial Hypertension

**Nobuhiro Kikuchi** , Kimio Satoh, Tohoku Univ, Sendai, Japan; Taijyu Satoh, Pittsburgh university, Pittsburgh, PA; Junichi Omura, Laval Univ, Quebec City, QC, Canada; Ryo Kurosawa, Nobuhiro Yaoita, Mohammad Abdul Hai Siddique, Satoshi Miyata, Hiroaki Shimokawa, Tohoku Univ, Sendai, Japan

1:30 PM

Board # 2207

The Association Between Vascular Resistance and Mortality in Patients With Pulmonary Hypertension

**Bradley A Maron** , Brigham and Womens Hosp, Boston, MA; Edward Hess, Veterans Affairs Eastern Colorado Health Care System, Denver, CO; Ryan J Tedford, Medical Univ South Carolina, Charleston, SC; Gabor Kovacs, Horst Olschewski, Boltzmann Lung Inst, Graz, Austria; Jane A Leopold, Brigham Womens Hosp, Boston, MA; Nazzareno Galie, Univ of Bologna, Bologna, Italy; Gerald Simonneau, Hôpital Antoine-Béclère, Paris, France; Marc Humbert, Univ Paris Sud, Le Kremlin-Bicetre, France; Anna Baron, Veterans Affairs Eastern Colorado Health Care System, Aurora, CO; Evan Brittain, Vanderbilt Univ, Nashville, TN; Gaurav Choudhary, Providence VAMC, Brown Univ, Providence, RI

1:30 PM

Board # 2208

High-sensitivity Troponin T Predicts Mortality Independently Of Ventricular Dysfunction And Pulmonary Hypertension In Stable Chronic Obstructive Pulmonary Disease

**Brede Kvisvik** , Akershus Univ Hosp, Lørenskog, Norway; Ingunn Skjørten, LHL Glittre Clinic, Jessheim, Norway; Janne M Hilde, Akershus Univ Hosp, Lørenskog, Norway; Heidi Strand, Akershus Univ Hosp, Lorenskog, Norway; Torbjørn Omland, Kjetil Steine, Akershus Univ Hosp, Lørenskog, Norway

1:30 PM

Board # 2209

Pilot Study on the Utility of Biomarkers and the Updated ISHLT Primary Graft Dysfunction Scoring Guidelines in Lung Transplantation

Lourdes Chacon, Texas Heart Inst, Houston, TX; Gabriel Loor, Baylor Coll of Med, Houstonr, TX; Daoud Daoud, Baylor Coll of Med, Houston, TX; Jonathan Mase, Hassan Virk, Texas Heart Inst, Houston, TX; Natalie Debolske, Hyewon Choi, Peter Jindra, Matthew Cusick, Baylor Coll of Med, Houston, TX; Luiz Sampaio, **Doris A Taylor** , Texas Heart Inst, Houston, TX

1:30 PM

Board # 2210

The Gender Difference in Pulmonary Arterial Hypertension: Analysis by Exercise Echocardiography

**Toru Takase** , Kindai Univ Faculty of Med, Osakasayama, Japan; Yoshitaka Iwanaga, Kindai Univ Faculty of Medici, Osakasayama, Japan; Mitsugu Taniguchi, Osaka Pref. Saiseikai Tondabayashi Hosp, Tondabayashi, Japan; Yutaka Hirano, Kindai Univ Faculty of Med, Osakasayama, Japan; Shunichi Miyazaki, Osaka Pref. Saiseikai Tondabayashi Hosp, Tondabayashi, Japan

1:30 PM

Board # 2211

Hematologic Changes, Particularly Rising Red Cell Distribution Width, Precede Pulmonary Arterial Hypertension (PAH) Diagnosis

**Timothy E Thayer** , Eric Farber-Eger, Vanderbilt Univ Medical Ctr, Nashville, TN; Evan Brittain, Vanderbilt Univ, Nashville, TN

1:30 PM

Board # 2213

Non-invasive Vocal Biomarker is Associated With Pulmonary Hypertension

**Jaskanwal Deep Singh S Sara** , Elad Maor, Barry A Borlaug, Diana Orbelo, Lilach O Lerman, Amir Lerman, Mayo Clinic, Rochester, MN

1:30 PM

Board # 2214

Combination of Right Ventricular Function and Pulmonary Pressure Improves Prediction of Adverse Outcome in Acute Pulmonary Embolism

**Mads Dam Lyhne** , Aarhus Univ Hosp, Aarhus N, Denmark; Christopher Kabrhel, Nicholas Giordano, Massachusetts General Hosp, Boston, MA; Asger Andersen, Jens Erik Nielsen-Kudsk, Aarhus Univ Hosp, Aarhus N, Denmark; Hui Zheng, David M Dudzinski, Massachusetts General Hosp, Boston, MA

1:30 PM

Board # 2215

Right Ventricular Dyssynchrony is a Predictor of Mortality in Patients With Precapillary Pulmonary Hypertension. A Cardiac Magnetic Resonance Study

Sophia-Anastasia Mouratoglou, Aristotle Univ of Thessaloniki, Thessaloniki, Greece; Alexandros Kallifatidis, St. Luke Clinic, Thessaloniki, Greece; Konstantinos Kouskouras, Aristotle Univ of Thessaloniki, Thessaloniki, Greece; Dimitrios Farmakis, Papageorgiou Hosp, Thessaloniki, Greece; Irini Nikolaou, Christos Feloukidis, Alexandros Evangeliou, Alexandra Arvanitaki, Charalampos I Karvounis, **George Giannakoulas** , Aristotle Univ of Thessaloniki, Thessaloniki, Greece

1:30 PM

Board # 2216

Hemoglobin and Cause-specific Mortality in Patients With Heart Failure With Preserved Ejection Fraction

**Kartik Gupta** , Univ of Alabama at Birmingham, Birmingham, AL; Rajat Kalra, Univ of Minnesota, Minneapolis, MN; Nitin J Gharpure, Mike Pate, Sudeep Aryal, Sameer Ather, Joanna M Joly, Indranee Rajapreyar, Sumanth D Prabhu, Navkaranbir Singh Bajaj, Univ of Alabama at Birmingham, Birmingham, AL

1:30 PM

Board # 2217

Aortic Valve Stenosis and Regurgitation Cause Pulmonary Hypertension Due to Left Heart Disease in New Zealand Obese Mice

**Jana Grune** , Charite - Univsmedizin Berl, Berlin, Germany; Christiane Ott, German Inst of Human Nutrition, Potsdam-Rehbruecke, Germany; Kathleen Pappritz, Jonathan Lauryn, Niklas Hegemann, Charité - Univeatsmedizin Berlin, Berlin, Germany; Cathleen John, German Inst of Human Nutrition, Potsdam-Rehbruecke, Germany; Robert Klopfleisch, Freie Univ Berlin, Berlin, Germany; Ulrich Kintscher, Charité - Univeatsmedizin Berlin, Berlin, Germany; Tilman Grune, German Inst of Human Nutrition, Potsdam-Rehbruecke, Germany; Wolfgang Kuebler, Charité - Univeatsmedizin Berlin, Berlin, Germany

1:30 PM

Board # 2218

A Multiscale Model of Cardiac Remodeling Under Pulmonary Arterial Hypertension: From Organ to Titin

**Reza Avaz** , Emilio Mendiola, Univ of Texas at Austin, Austin, TX; Richard A F Dixon, Texas Heart Inst, Houston, TX; Michael Sacks, Univ of Texas at Austin, Austin, TX

# Abstract Poster Session

## AT.APS.05 - Metabolic Syndrome and Cardiovascular Disease

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1066

The Hispanic Paradox in County-level Obesity Prevalence

**Areli Valencia** , Bongeka Zilindile Zuma, Stanford Univ, Palo Alto, CA; Gabriel Michael Knight, Northwestern Univ, Chicago, IL; David Scheinker, Stanford Univ Sch of Engineering, Stanford, CA; Ashish Sarraju, Stanford Univ, Palo Alto, CA; Fatima Rodriguez, Stanford Univ Sch of Med, Palo Alto, CA

1:30 PM

Board # 1067

Sleep Disordered Breathing is a Component of Metabolic Syndrome in Adolescents and Adults

**Fan He** , Julio Fernandez-Mendoza, Penn State Coll of Med, Hershey, PA; Edward O Bixler, Penn State Univ, Hershey, PA; Alexandros Vgontzas, Penn State, Hershey, PA; Duanping Liao, Penn State Univ Coll of Med, Hershey, PA

1:30 PM

Board # 1068

Diabetes is Associated With Increased Risk of Thromboembolism Independent of Type of Diabetes Treatment in Patients With Atrial Fibrillation Undergoing Coronary Angiography

Michael Maeng, Aarhus Univ Hosp, Aarhus N, Denmark; Raffaele De Catarina, Univ Hosp of Pisa, Pisa, Italy; Morten Würtz, Regional Hosp West Jutland, Herning, Denmark; Pernille Gro Thrane, Christine Gyldenkerne, Steen Dalby Kristensen, **Kevin Kris Warnakula Olesen** , Aarhus Univ Hosp, Aarhus N, Denmark

1:30 PM

Board # 1069

Small Dense Low Density Lipoprotein Cholesterol as a Cardiovascular Risk Assessment; Results From Framingham Offspring Study

**Hiroaki Ikezaki** , HNRCA at Tufts Univ, Boston, MA; Elise Lim, Ching-Ti Liu, Boston Univ Sch of Public Health, Boston, MA; L Adrienne Cupples, Boston U Sch of Public Health, Boston, MA; Katsuyuki Nakajima, Nakajima Assoc Co LTD, Mdehashi, Japan; Bela F Asztalos, Tufts Univ, Boston, MA; Masayuki Murata, Norihiro Furusyo, Kyushu Univ Hosp, Fukuoka, Japan; Ernst J Schaefer, Tufts Univ, Boston, MA

1:30 PM

Board # 1070

Chronic Enhancement of Endogenous Nitric Oxide Production via Whole Body Periodic Acceleration (wbpa) Induces Cardioprotection in 15 Months Diabetic Mice

Arkady Uryash, Mount Sinai Medical Ctr Res, Miami Beach, FL; Valentina Flores, Juan Kolster, Ctr de Investigaciones Biomedicas, Veracruz, Mexico; Jose R Lopez, **Jose Antonio Adams** , Mount Sinai Medical Ctr, Miami Beach, FL

1:30 PM

Board # 1071

Thymidine Phosphorylase Enhances Diabetes-associated High-risk of Thrombosis

**Adam M Belcher** , Marshall Univ Joan C. Edwards Sch of Med, Huntington, WV; Abu Hasanat Md Zulfiker, Hong Yue, Marshall Univ Joan C. Edwards, Huntington, WV; Li Wei, Marshall Univ, Huntington, WV

1:30 PM

Board # 1072

Simple Lab Indicators of Risk and Cardiac Intensive Care Unit Outcomes: Analysis From the Critical Care Cardiology Trials Network

**Siddharth M Patel** , Erin A Bohula, David D Berg, Jeong-Gun Park, Brigham and Women's Hosp, Boston, MA; Sean Van Diepen, Univ of Alberta, Edmonton, AB, Canada; Jason N Katz, Univ of North Carolina, Chapel Hill, NC; David A Morrow, Brigham and Women's Hosp, Boston, MA; on behalf of the CCCTN Investigators

1:30 PM

Board # 1073

Lipoprotein (a) and Risk of Chronic Kidney Disease Among 4235 Japanese Hospitalized Patients

**Hayato Tada** , Taiji Yoshida, Kanazawa Univ, Kanazawa, Japan; Ryota Teramoto, Masayuki Takamura, Kanazawa Univ Hosp, Kanazawa, Japan; Masa-aki Kawashiri, Kanazawa Univ, Kanazawa, Japan

1:30 PM

Board # 1074

**Molecular Mechanism of Chronic Beta** 3 **-Adrenergic Receptor Blockade-Caused Regression of Cardiac Dysfunction in a Diabetic Mouse Model: Effects on the Express of Cardiac SR Ca** 2+ **-ATPase, Subtypes of Beta-Adrenergic Receptors and Nitric Oxide Synthase Isoforms and Nitrotyrosine**

**Heng-Jie Cheng** , Yixi Liu, Zhe Chen, Alexei V Mikhailov, Jen-Jar Lin, Dalane Kitzman, Donald A McClain, Che Ping Cheng, Wake Forest Sch of Med, Winston-Salem, NC

1:30 PM

Board # 1075

Low-Carbohydrate Diet Does Not Improve Flow-Mediated Dilation In Obese Adults

**Chueh-Lung Hwang** , Christine Ranieri, Abeer M Mahmoud, Shane A Phillips, Univ of Illinois at Chicago, Chicago, IL

# Abstract Poster Session

## IM.APS.02 - MRI: Coronary Artery Disease, Ischemia and Infarction

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Gregory Kicska, Seattle, WA

1:30 PM

Board # 4151

Histological Tissue Characterization Of Coronary High Intensity Plaques On Non-contrast T1 Weighted Magnetic Resonance Imaging In Patients With Cardiovascular Diseases: An Ex-vivo Study

**Yasuhide Asaumi** , Teruo Noguchi, Natl Cerebral & Cardiovasc Ctr, Suita, Japan; Yoshiaki Morita, Tohoku Univ, Sendai, Japan; Fumiyuki Otsuka, Natl Cerebral & Cardiovasc Ctr, Suita, Japan; Taka-aki Matsuyama, Showa Univ, Tokyo, Japan; Kazuhiro Nakao, Yu Kataoka, Hatsue Ishibashi-Ueda, Natl Cerebral & Cardiovasc Ctr, Suita, Japan; Satoshi Yasuda, Natl Cereb Cardiovascular Ctr, Osaka, Japan

1:30 PM

Board # 4152

Stress Cardiac Magnetic Resonance Imaging Provides Incremental Prognostic Value in Patients With Suspected Stable Coronary Artery Disease: Results From the Multicenter Spins Trial

**Panagiotis Antiochos** , Brigham and Women's Hosp, Harvard Univ, Boston, MA; Yin Ge, Brigham And Women's Hosp, Boston, MA; Ayako Seno, Brigham and Women's Hosp, Brookline, MA; Kevin Steel, Methodist Hosp San Antonio, San Antonio, TX; Shuaib Abdullah, Southwestern Medical Ctr, Univ of Texas, Dallas, TX; Scott E Bingham, Central Utah Clinic, Provo, UT; J Ronald Mikolich, Sharon Regional Health System, Youngstown, OH; John F Heitner, New York Methodist Medical Associates, Brooklyn, NY; Andrew E Arai, NIH NHLBI, Bethesda, MD; Wiphada Patricia Bandettini, Natl Insts of Health, Bethesda, MD; Amit R Patel, Univ of Chicago Med, Chicago, IL; Afshin Farzaneh-Far, Univ of Illinois, Chicago, IL; Subha V Raman, Ohio State Univ Wexner Medical Ctr, Columbus, OH; Chetan Shenoy, Univ of Minnesota, Minneapolis, MN; Jorge Gonzalez, Univ of Virginia Health System, Charlottesville, VA; Steve W Leung, Univ of Kentucky, Lexington, KY; Dipan J Shah, Houston Methodist Hosp, Houston, TX; Victor A Ferrari, Univ Of Penn. Medical Ctr, Philadelphia, PA; Jeanette Schulz-Menger, Charite Campus Buch, Berlin, Germany; Rory Hachamovitch, Cleveland Clinic, Cleveland, OH; Matthias Stuber, Univ Hosp of Lausanne, Lausanne, Switzerland; Orlando P Simonetti, Siemens Medical Systems, Chicago, IL; Raymond Kwong, Brigham and Women's Hosp, Boston, MA

1:30 PM

Board # 4153

Coronary Perivascular Adipose Tissue Thickness is Associated With Larger Infarct Size and Lower Left Ventricular Ejection Fraction in STEMI Patients

**Michel T Corban** , Takumi Toya, John Bois, Lilach O Lerman, Amir Lerman, Mayo Clinic, Rochester, MN

1:30 PM

Board # 4154

Left Ventricular Scar Detection in Hypertrophic Cardiomyopathy: A Radiomic Analysis of Steady-state Free Precession Cine Cardiac MRI

**Jennifer Mancio** , Harvard Medical Sch, Boston, MA; Farhad Pashakhanloo, Harvard Medical Sch, BIDMC, Baltimore, MD; Hossam El-Rewaidy, Harvard Medical Sch, BOSTON, MA; Ethan Rowen, Tufts Medical Ctr, Boston, MA; Warren J Manning, Beth Israel Deaconess Med Ctr, Boston, MA; Martin S Maron, Tufts Medical Ctr, Boston, MA; Reza Nezafat, Beth Israel Deaconess Medical Ctr & Harvard Medical Sch, Boston, MA

1:30 PM

Board # 4155

Role of T1 Mapping and Extracellular Volume in Evaluating the Interstitial Matrix in Diabetic Patients With Stable Coronary Artery Disease

**Gustavo A. B. Boros** , Whady Hueb, Insto do Coração (InCor), Hosp das Clínicas HCFMUSP, Faculdade de Medicina da Univ de São Paulo, Sao Paulo, Brazil; Paulo C Rezende, Heart Inst-FMUSP, Sao Paulo, Brazil; Rosa M. R. Garcia, Insto do Coração (InCor), Hosp das Clínicas HCFMUSP, Faculdade de Medicina da Univ de São Paulo, Sao Paulo, Brazil; Carlos Eduardo Rochitte, INCOR Univ.Sao Paulo HCOR Heart Hosp, Sao Paulo, Brazil; Cesar H Nomura, Massachusetts General Hosp, Boston, MA; Anderson Roberto Dallazen, Insto do Coração (InCor), Hosp das Clínicas HCFMUSP, Faculdade de Medicina da Univ de São Paulo, São Paulo, Brazil; Thamara Carvalho Morais, InCor - Heart Inst FMUSP, São Paulo, Brazil; Matheus Ribeiro, Heart Inst HC-FMUSP, Sao Paulo, Brazil; Carlos Vicente Serrano Jr., Heart Inst (InCor), Sao Paulo SP, Brazil; Jose A Ramires, Rua Almiravitre Soares, Sao Paulo, Brazil; Roberto Kalil, Insto do Coração (InCor), Hosp das Clínicas HCFMUSP, Faculdade de Medicina da Univ de São Paulo, Sao Paulo, Brazil

1:30 PM

Board # 4156

Left Ventricular Ischemia and Infarction Each Independently Augment Risk for Functional Mitral Regurgitation - A Multicenter Stress Cardiac Magnetic Resonance Study of >8,000 Patients

**Jonathan Kochav** , Weill Cornell Medical Ctr, New York, NY; Raymond J Kim, Duke Univ Medical Ctr, Durham, NC; Ramsey Kalil, Michael Villanueva, Weill Cornell Medical Ctr, New York, NY; Han Kim, Duke Cardiovascular Magnetic Resonance Ctr, Durham, NC; Igor Klem, Duke Univ Medical Ctr, Chapel Hill, NC; Preston Cargile, Heart Imaging Technologies, Durham, NC; Robert Judd, Duke Cardiovascular Magnetic Resonance Ctr, Dunham, NC; Chetan Shenoy, Andrew Hughes, Univ of Minnesota Medical Ctr, Minneapolis, MN; Dipan Shah, Dany Debs, Houston Methodist DeBakey Heart and Vascular Ctr, Houston, TX; John F Heitner, NYP Brooklyn Methodist Hosp, Brooklyn, NY; Afshin Farzaneh-Far, Univ of Illinois at Chicago, Chicago, IL; Venkateshwar Polsani, Piedmont Atlanta Hosp, Atlanta, GA; Michele Parker, Duke Cardiovascular Magnetic Resonance Ctr, Durham, NC; Robert A Levine, Massachusetts General Hosp, Boston, MA; Jiwon Kim, Jonathan W Weinsaft, Weill Cornell Medical Ctr, New York, NY

1:30 PM

Board # 4157

Aortic Stiffness is Associated With a Reduced Coronary Flow Reserve

**Jonathan J Lee** , Univ of Pennsylvania, Philadelphia, PA; Rushik Bhuva, Geisinger Wyoming Valley Med. Cen., Canton, OH; Bilal Ansari, Mary Jo Obeid, Univ of Pennsylvania, Philadelphia, PA; Sowjanya Yenigalla, UPMC, Pittsburgh, PA; Armghan H Ans, Garrett Oldland, Univ of Pennsylvania, Philadelphia, PA; Zeba Hashmath, Saint Vincent Hosp, Worcester, MA; Anila Hussain, Gurpreet Singh, Qasim Jehangir, Univ of Pennsylvania, Philadelphia, PA; Vaibhav Satija, Saint Vincent Hosp, Worcester, MA; Walter R Witschey, Univesity of Pennsylvania, Philadelphia, PA; Sujith Kuruvilla, Univ of Pennsylvania, Philadelphia, PA; Scott Akers, Philadelphia VA Medical Ctr, Philadelphia, PA; Julio A Chirinos, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 4158

Coronary Flow Reserve by Cardiac Magnetic Resonance Imaging in Patients With Ischemic Cardiomyopathy With Diabetes Mellitus

**Shingo Kato** , Kazuki Fukui, Sho Kodama, Keigo Hayakawa, Mai Azuma, Minako Kagimoto, Kohei Iguchi, Masahiro Fukuoka, Tae Iwasawa, Kanagawa Cardiovasc Respiratory Ctr, Yokohama, Japan; Daisuke Utsunomiya, Yokohama City Univ Hosp, Yokohama, Japan; Masami Kosuge, Kazuo Kimura, Yokohama City Univ Medical Ctr, Yokohama, Japan; Kouichi Tamura, Yokohama City Univ, Yokohama, Japan

1:30 PM

Board # 4159

Semi-Quantitative CMR Analysis of Left Anterior Descending Territory Ischaemia in Patients With a Right Coronary Artery Chronic Total Occlusion

**Richard EK Jones** , Natl Heart and Lung Inst, London, United Kingdom; Daniel Hammersley, Natl Heart and Lung Inst, London; Grigoris V Karamasis, Shah R Mohdnazri, Essex Cardiothoracic Ctr, Basildon, United Kingdom; Jason N Dungu, Essex Cardiothoracic Ctr, London, United Kingdom; Swamy Gedela, Essex Cardiothoracic Ctr, Basildon, United Kingdom; Klio Konstantinou, Osama Alsanjari, Essex Cardiothoracic Ctr, London, United Kingdom; Peter Gatehouse, Royal Brompton Hosp, London; Brian Halliday, Imperial Coll, London, London; Amrit Lota, Imperial Coll London, London; Kare H Tang, Essex Cardiothoracic Ctr, London, United Kingdom; Paul A Kelly, Natl Heart and Lung Inst, Basildon, United Kingdom; Sanjay Kumar Prasad, Royal Brompton Hosp, London, United Kingdom; John R Davies, Essex Cardiothoracic Ctr, Basildon, United Kingdom; Thomas R Keeble, Natl Heart and Lung Inst, Basildon, United Kingdom

1:30 PM

Board # 4163

The Impact of Perivascular Epicardial Adipose Tissue on Microvascular Obstruction After ST-segment Elevation Myocardial Infarction

Takumi Toya, Michel T Corban, John P Bois, Lilach O Lerman, **Amir Lerman** , Mayo Clinic, Rochester, MN

1:30 PM

Board # 4160

Correlation of a Zero Calcium Score With Obstructive Coronary Artery Disease in a Middle Eastern Population Using Computerized Tomography

**Noora Alhajri** , Natl Inst of Health, Baltimore, MD

1:30 PM

Board # 4161

The Distribution of Coronary Artery Calcium by Body Mass Index and Waist-Hip Ratio in Health Check-Up Registry

**Hyeonju Jeong** , Myongji Hosp, Hanyang Univ Medical Ctr, Goyang, Korea, Republic of; Ji Hyun Lee, Myongji Hosp, Goyang-si Gyeonggi-do, Korea, Republic of; Mihyun Kim, Eui-Seok Hwang, Yongsung Suh, Yoon-Hyeong Cho, Deok-Kyu Cho, Myongji Hosp, Hanyang Univ Medical Ctr, Goyang, Korea, Republic of

1:30 PM

Board # 4162

4d Flow Magnetic Resonance Assessment of Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy and Surgical Valve Replacement for Aortic Valve Stenosis

**Rie Aoyama** , Joji Ishikawa, Hajime Fujimoto, Kazumasa Harada, Tokyo Metropolitan Geriatric Hosp, Tokyo, Japan

# Abstract Poster Session

## CH.APS.03 - New Discoveries in Clinical Pediatric Electrophysiology

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4057

**Precision Medicine for the Trafficking Defective Mutation, p. N633S, in the Type 2 Long QT Syndrome-associated,** KCNH2 **-encoded Kv11.1 Channel Using Patient-specific Re-engineered Cardiomyocytes**

**Samantha K Hamrick** , CS John Kim, David J Tester, Michael J Ackerman, Mayo Clinic, Rochester, MN

1:30 PM

Board # 4058

**Whole Exome Molecular Autopsy With Copy Number Variant Analysis of Multiple Autopsy Negative Sudden Unexplained Deaths Among Amish Siblings Yields the Discovery of a Novel Homozygous Multi-exon Duplication in the** Ryr2- **Encoded Ryanodine Receptor**

**David J Tester** , Mayo Clinic Coll of Med, Rochester, MN; Hannah M Bombei, Univ of Iowa, Stead Family Children's Hosp, Iowa City, IA; Kristi K Fitzgerald, Nemours, Alfred I. duPont Hosp for Children, Wilmington, DE; John Giudicessi, Mayo Clinic, Rochester, MN; Beth A Pitel, Erik C Thorland, Mayo Clinic Coll of Med, Rochester, MN; Barbara Russell, ULP- Pediatric Cardiology, Louisville, KY; Samantha K Hamrick, CS John Kim, Carla M Haglund-Turnquist, Mayo Clinic Coll of Med, Rochester, MN; Christopher Johnsrude, Univ of Louisville, Louisville, KY; Dianne L Atkins, Univ of Iowa, Iowa City, IA; Luis A Ochoa, Univ of Iowa, Stead Family Children's Hosp, Iowa City, IA; Ian H Law, Univ of Iowa Children's Hosp, Iowa City, IA; Joel Temple, Nemours, Alfred I. DuPont Hosp for Children, Wilmington, DE; Michael John Ackerman, Mayo Clinic Coll of Med, Rochester, MN

1:30 PM

Board # 4059

Pericardial Adhesions Do Not Preclude Minimally Invasive Epicardial Pacemaker Lead Placement in an Infant Porcine Model

**Rohan N Kumthekar** , Lok M Sinha, Children's Natl Health System, Washington, DC; Justin D Opfermann, Paige Mass, Sheikh Zayed Inst for Pediatric Surgical Innovation, Washington, DC; Bradley C Clark, Children's Hosp at Montefiore, Bronx, NY; Can Yerebakan, Children's Natl Health System, WASHINGTON, DC; Charles I Berul, Children's Natl Health System, Washington, DC

1:30 PM

Board # 4060

Peri: A Training Phantom for Pediatric Cardiac Ablation

**Paige N Mass** , Justin Opfermann, Rohan N Kumthekar, Charles I Berul, Children's Natl, Washington, DC

1:30 PM

Board # 4061

Anodal Capture Frequently Occurs With Temporary Pacing After Pediatric Cardiac Surgery

**Chalese Richardson** , Leonardo Liberman, Eric S Silver, Columbia Univ Irving Medical Ctr, New York, NY

1:30 PM

Board # 4062

Quantitative Assessment of Ventricular Function in Fontan Patients With Dual-site Ventricular Pacing

**Jeremiah Joyce** , Edward O'Leary, Jonathan Rhodes, Children's Hosp, Boston, MA

1:30 PM

Board # 4063

A Novel Machine Learning Algorithm Can Identify Septal Accessory Pathway Location on Pre-Procedural ECG in Children With Wolff-Parkinson-White Syndrome

**Antonio J Escobar** , Jin Long, Marco Valentin Perez, Anne M Dubin, Kara Motonaga, Henry Chubb, Anthony Trela, Debra G Hanisch, Scott R Ceresnak, Stanford Univ, Palo Alto, CA

1:30 PM

Board # 4064

The Electrophysiology of Fetal Long QT Syndrome

Sarah Strand, Univ of Wisconsin-Madison, Madison, WI; Janette F Strasburger, Childrens Hosp Wisconsin, Milwaukee, WI; Bettina F Cuneo, Childrens Hosp Colorado, Aurora, CO; **Ronald Wakai** , Univ of Wisconsin-Madison, Madison, WI

1:30 PM

Board # 4065

Impact of Ventricular Arrhythmias on Outcomes in Children With Myocarditis: An Analysis of the National Inpatient Sample Database

**Hasan F. Othman** , Cleveland Clinic Children's, Cleveland, OH; Iman Aly, The George Washington Univ Sch of Med and Health Sciences, Washington, DC; Mohammed Hamzah, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 4066

Depression, Anxiety, and Attention Deficit Hyperactivity Disorder in Youth With Cardiac Arrhythmias: A Cross Sectional Comparative Study

**Keila N Lopez** , Vincent J Gonzalez, Katherine E Cutitta, John Shabosky, Mohammad F Bilal, Baylor Coll of Med, Houston, TX; Rachel T Kimbro, Rice Univ, Houston, TX

1:30 PM

Poster Professor

Jeffrey P. Moak, Washington, DC

1:30 PM

Board # 4067

Change From Baseline and Initial Post-Chemotherapy Echocardiographic Shortening Fraction Predicts Long-Term Cardiac Dysfunction in Patients With Anthracycline Chemotherapy Exposure

**Jason Matthew Cole** , Zachary Daniels, Nationwide Children's Hosp, Columbus, OH; May Mah, Nationwide Childrens Hosp, Columbus, OH; Simon Lee, Randal Olshefski, Nationwide Children's Hosp, Columbus, OH; Olga Tora-Salazar, Connecticut Children's Medical Ctr, Hartford, CT; Deipanjan Nandi, Kan N Hor, Nationwide Children's Hosp, Columbus, OH

# Abstract Poster Session

## HY.APS.02 - Optimal Control of Hypertension

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2155

Blood Pressure Variability Improves With Digital Management Over Usual Care

**Richard V Milani** , Jonathan K Wilt, Ochsner Health System, New Orleans, LA; Alexander R Milani, Emory Univ Sch of Med, Atlanta, GA; Robert Bober, Eric Malamud, Jonathan Entwisle, Carl Joseph Lavie Jr., Ochsner Health System, New Orleans, LA

1:30 PM

Board # 2156

Blood Pressure Reduction in Patients With Orthostatic Hypertension in the SPYRAL HTN-OFF Med Trial

**Kazuomi Kario** , JICHI Medical Univ, Tochigi-ken, Japan

1:30 PM

Board # 2157

Target Blood Pressure Control in Patients With Acute Coronary Syndrome

**Ki Hong Lee** , Chonnam Natl Univ Hosp, Gwangju, Korea, Republic of

1:30 PM

Board # 2160

Left Atrial Stiffness Index as a Biomarker of Early Target Organ Damage in Hypertension

**Yan Liu** , Yixiao Zhao, Qiaobing Sun, Yan Lu, Ying Zhang, Wei Song, Yunpeng Cheng, Tao Cong, Yinong Jiang, The First Affiliated Hosp of Dalian Medical Univ, Dalian, China

1:30 PM

Board # 2161

The Role of Coronary Artery Calcium as a Risk Enhancer to Personalize Treatment in Stage 1 Hypertension - The Multi-ethnic Study of Atherosclerosis

**Amal Abdellatif** , Mohamed Elshazly, Soha Dargham, Weill Cornell Med-Qatar, Doha, Qatar; Renato Quispe, Johns Hopkins Ciccarone Ctr, Bronx, NY; Miguel Cainzos-Achirica, Johns Hopkins, Baltimore, MD; Seth S Martin, Johns Hopkins Hosp, Baltimore, MD; Joseph Yeboah, Wake Forest Univ, Winston Salem, NC; Bruce M Psaty, Univ Washington, Seattle, WA; Wendy S Post, Johns Hopkins Hosp, Baltimore, MD; Khurram Nasir, Baptist Health South Florida, New Haven, CT; Matthew J Budoff, Los Angeles Biomedical Res, Torrance, CA; Roger S Blumenthal, Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; John W McEvoy, Natl Inst of Preventive Cardiology, Cork, Ireland

1:30 PM

Board # 2162

Evaluation of Treatment With Angiotensin Converting Enzyme Inhibitors (ACEIs) and the Risk of Lung Cancer (ERACER)

**Jeffrey Lance Anderson** , Intermountain Medical Ctr, Murray, UT; Kirk Ute Knowlton, Intermountain Medical Ctr, Salt Lake City, UT; Joseph B Muhlestein, Intermountain Medical Ctr; Univ of Utah, Salt Lake City, UT; Tami L Bair, Intermountain Medical Ctr, Salt Lake Cty, UT; Donald L Lappe, Viet T LE, Santanu Biswas, Intermountain Medical Ctr, Salt Lake City, UT; Benjamin D Horne, Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT

1:30 PM

Board # 2163

Development and Validation of a Novel Non-Invasive Cuff-Less Blood Pressure Monitoring Device

**Kazuhiro Sumitomo** , Hideyuki Kato, Atsuhiro Kanno, Masakazu Suzuki, Takao Nakano, Tohoku Medical and Pharmaceutical U, Sendai, Japan; Ilya Fine, ELFI-TECH Ltd, Rehovot, Israel; Ori Braitbart, ELFI-TECH Ltd., Rehovot, Israel; Tatsuya Komaru, Tohoku Medical and Pharmaceutical Univ, Sendai, Japan; Naoyuki Hasebe, Asahikawa Medical Univ, Asahikawa, Japan

1:30 PM

Board # 2164

Sodium-Glucose Cotransporter 2 Inhibitors Reduce Residual Cardiovascular Risk in Heart Failure With Preserved Ejection Fraction

**Takaaki Sakai** , Ichijyukai NISHIO Hosp, Nogata, Japan; Shinichiro Miura, Fukuoka Univ Sch of Med, Fukuoka, Japan

# Abstract Poster Session

## CH.APS.02 - Pediatric Prevention & Acquired Vasculopathies

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4045

Poor Lipid Screening Rates in United States Children and Adolescents: A Call to Action for Pediatric Health Care Providers

**Justin H Berger** , Feiyan Chen, Jennifer A Faerber, Michael L O'Byrne, Julie A Brothers, The Children's Hosp of Philadelphia, Philadelphia, PA

1:30 PM

Board # 4046

Metabolomic Fingerprinting Identifies Significant Metabolic Pathway Alterations in Infants With Single Ventricle Heart Disease Prior to Superior Cavo-Pulmonary Anastomosis

**Benjamin S Frank** , Karlise Lewis, Ludmila Khailova, Lori Silveira, Children's Hosp Colorado, Aurora, CO; Max B Mitchell, Univ of Colorado, Aurora, CO; Gareth Morgan, Univ of Colorado - Children's, Aurora, CO; Mark Twite, Univ of Colorado Denver, Aurora, CO; Michael V Di Maria, Children's Hosp Colorado, Aurora, CO; Jelena Klawitter, Univ of Colorado AMC, Aurora, CO; Jesse Davidson, Univ of Colorado, Denver, CO

1:30 PM

Board # 4047

Yield of Genetic Testing for Familial Hypercholesterolemia in a Cohort of Urban Minority Pediatric Patients

Sadahf Shujauddin, Ellis Rochelson, The Children's Hosp at Montefiore, Bronx, NY; **Joseph Mahgerefteh** , Children's Hosp at Montefiore, Bronx, NY

1:30 PM

Board # 4048

Shear Stress Regulates Klf2 and Klf4 in Pulmonary Vein Endothelial Cells

**Rachel D Vanderlaan** , Yaqin Yana Fu, Yanting Wang, Hosp for Sick Children, Toronto, ON, Canada; Christopher Caldarone, Texas Childrens Hosp, Houston, TX

1:30 PM

Board # 4049

Racial Difference in Clinical and Epidemiological Characteristics of Kawasaki Disease in Southeast US

**Luz A Padilla** , Jacqueline L Collins, Adeniyi J Idigo, Univ of Alabama at Birmingham, Birmingham, AL; Yung R Lau, Univ Alabama Birmingham, Birmingham, AL; Michael A Portman, Seattle Childrens, Seattle, WA; Sadeep Shrestha, Univ of Alabama at Birmingham, Birmingham, AL

1:30 PM

Board # 4050

Analysis of the Factors Associated With Coronary Arterial Aneurysm Regression in Patients With Kawasaki Disease

**Taichi Kato** , Naoya Univ, Nagoya, Japan; Tohru Kobayashi, The Natl Ctr for Child Health and Development, Tokyo, Japan; Mamoru Ayusawa, Nihon Univ Sch of Med, Tokyo, Japan; Ryuji Fukazawa, Nippon Medical Sch, Tokyo, Japan; Shigeto Fuse, NTT East Japan Sapporo Hosp, SAPPORO, Japan; Keiichi Hirono, Univ of Toyama, Toyama, Japan; Yoshihide Mitani, MIE Univ Graduate Sch Med, Tsu City, Japan; Kenji Suda, Kurume Univ Sch of Med, Kurume City, Japan; Jun Maeda, Keio Univ Sch of Med, Tokyo, Japan; Masaru Miura, Tokyo Metropolitan Children's Medical Ctr, Tokyo, Japan

1:30 PM

Board # 4051

The Electrophysiological Index (Tp-e/QT) in Combination With Clinical Risk Score Can Effectively Predict Subsequent Coronary Artery Aneurysm Formation in Children With Kawasaki Disease

**Tadayoshi Hata** , Hirofumi Kusuki, Fujita Health Univ, Toyoake, Japan; Tsuneaki Sadanaga, Seigato Hosp, Kumamoto, Japan; Takanori Suzuki, Aichi Children's Health and Medical Ctr, Oobu, Japan; Arisa Kojima, Hidetoshi Uchida, Fujita Health Univ, Toyoake, Japan; Yoshihiko Eryu, Toyokawa City Hosp, Toyokawa, Japan; Kazuyoshi Saito, Fujita Health Univ, Toyoake, Japan

1:30 PM

Board # 4052

Next Generation Sequencing in Kawasaki Disease: A Pilot Study

**Dongngan Truong** , Univ of Utah/Primary Children's Hosp, Salt Lake Cty, UT; Luann Minich, Univ of Utah, Salt Lake City, UT; Edwin Lin, Univ of Utah, Salt Lake Cty, UT; Richard V Williams, Univ of Utah, Salt Lake City, UT; Robert Schlaberg, Univ of Utah, Salt Lake Cty, UT; Linda M Lambert, Univ of Utah-PCH Heart Ctr, Salt Lake City, UT; Yueqin Yang, Igor Areinamo, Krow Ampofo, Univ of Utah, Salt Lake Cty, UT; Martin Tristani-Firouzi, Primary Childrens Univ of Utah, Salt Lake City, UT

1:30 PM

Board # 4053

High-dose vs. Low-dose Ivig For Kawasaki Disease Children With a Weight of 25kg or More

**Takanori Suzuki** , Aichi Children's Health and Medical Ctr, Obu, Japan; Nobuaki Michihata, The Univ of Tokyo, Tokyo, Japan

1:30 PM

Board # 4054

Effectiveness of Continuous Intravenous Infusion of Cyclosporine A for Patients With Intravenous Immunoglobulin-Resistant Kawasaki Disease

**Mitsuru Seki** , Takaomi Minami, Tatsuya Anzai, Sadahiro Furui, Shun Suzuki, Tomoyuki Sato, Koichi Kataoka, Takanori Yamagata, Jichi Medical Univ, Tochigi, Japan

1:30 PM

Board # 4055

Associations Between Neighborhood Socio-Economic Status and Congenital Heart Disease and Exploring for Potential Environmental Injustice in Urban Alberta, Canada

**Deliwe P Ngwezi** , Univ of Alberta, Edmonton, AB, Canada; Lisa K Hornberger, Univ Alberta, Edmonton, AB, Canada; Jesus Serrano-Lomelin, Univ of Alberta, Edmonton, AB, Canada; Deborah S Fruitman, Alberta Children's Hosp, Calgary, AB, Canada; Alvaro Osornio-Vargas, Univ of Alberta, Edmonton, AB, Canada

1:30 PM

Board # 4056

Gene Knockouts Affecting Mitochondrial Proteins Account for Significant Embryonic and Neonatal Lethality: Data From the International Mouse Phenotyping Consortium

**Colin K Phoon** , NYU Fink Child Amb Care Ctr, New York, NY; Mindong Ren, NYU Sch of Med, New York, NY

# Abstract Poster Session

## VA.APS.01 - Population Trends in Lower Extremity Peripheral Artery Disease

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4293

Sex-Specific Differences in Symptomatic Peripheral Artery Disease: Insights From the EUCLID Trial

Axel Haine, Univ Hosp Bern, Bern; Sarah Kavanagh, Colorado Prevention Ctr, Aurora, CO; Jeffrey S Berger, New York Univ Sch Med, New York, NY; Francis G Fowkes, Univ of Edinburgh, Edinburgh, United Kingdom; Brian Katona, Astra Zeneca LP, Gaithersburg, MD; Kenneth Mahaffey, Stanford Univ, Stanford, CA; Lars Norgren, Örebro Univ, Sweden, Örebro, Sweden; Juuso I Blomster, Univ of Turku, T, Finland; William S Jones, Duke Univ Medical Ctr, Durham, NC; Manesh R Patel, Duke Medical Ctr, Durham, NC; William R. Hiatt, Univ of Colorado Sch Med, Aurora, CO; **Iris none Baumgartner** , Univ Hosp Bern, Bern, Switzerland

1:30 PM

Board # 4294

Chronic Kidney Disease and Outcomes of Lower Extremity Revascularization for Peripheral Artery Disease

**Nipun Bhandari** , Jeffrey S Berger, Nathaniel R Smilowitz, New York Univ Sch of Med, New York, NY

1:30 PM

Board # 4295

Long-Term Effect of Bariatric Surgery on the Incidence and Outcomes of Obesity-Related Peripheral Vascular Disease

Osama Moussa, **Maddalena Ardissino** , Silvia Muttoni, Ara Faraj, Alice Tang, Paul Ziprin, Ara Darzi, Imperial Coll London, London, United Kingdom; Omar Khan, St George's Univ, London, United Kingdom; Peter Collins, Royal Brompton, London; Usman Jaffer, Imperial Coll London NHS Trust, London, United Kingdom; Sanjay Purkayastha, Imperial Coll London, London, United Kingdom

1:30 PM

Board # 4296

Association of the Ankle-Brachial Index With Cardiovascular Events in Patients With Established Peripheral Artery Disease. Observations From the Euclid Trial

**William R. Hiatt** , Univ of Colorado Sch Med, Aurora, CO; Connie N Hess, Univ of Colorado, Aurora, CO; Marc P Bonaca, Sarah Kavanagh, CPC Clinical Res, Aurora, CO; Manesh R Patel, Duke Medical Ctr, Durham, NC; Iris none Baumgartner, Univ Hosp Bern, Bern; Jeffrey S Berger, New York Univ Sch Med, New York, NY; Juuso I Blomster, Univ of Turku, Turku, Finland; Francis G Fowkes, Univ of Edinburgh, Edinburgh, United Kingdom; William S Jones, Duke Univ Medical Ctr, Durham, NC; Brian Katona, Astra Zeneca LP, Gaithersburg, MD; Kenneth W Mahaffey, Stanford Univ, Stanford, CA; Lars Norgren, Orebro Univ, Orebro, Sweden

1:30 PM

Board # 4297

Differences in Cardiovascular Outcomes in Patients With Type 1 versus Type 2 Diabetes and Peripheral Arterial Disease

**Andrew S Tseng** , Marlene Girardo, Danish Atwal, Mayo Clinic, Scottsdale, AZ; David Liedl, Paul W Wennberg, Mayo Clinic, Rochester, MN; Fadi Shamoun, Mayo Clinic, Scottsdale, AZ

1:30 PM

Board # 4298

Risk Factor Control and Secondary Prevention of Cardiovascular Events in Peripheral Artery Disease: Insights From the Euclid Trial

Jeffrey S Berger, New York Univ Sch Med, New York, NY; **Brian Katona** , Astra Zeneca LP, Gaithersburg, MD; Hillary Mulder, Duke Clinical Res Inst, Durham, NC; Manesh R Patel, Duke Medical Ctr, Durham, NC; Frank W Rockhold, Duke Clinical Res Inst, Durham, NC; Iris none Baumgartner, Univ Hosp Bern, Bern; Juuso I Blomster, Univ of Turku, Turku, Finland; Francis G Fowkes, Univ of Edinburgh, Edinburgh, LA; William S Jones, Duke Univ Medical Ctr, Durham, NC; Kenneth Mahaffey, Stanford Univ, Stanford, CA; Lars Norgren, Örebro Univ, Sweden, Örebro, Sweden; William R. Hiatt, Univ of Colorado Sch of Med, Aurora, CO

1:30 PM

Board # 4299

Association Between Calf Muscle Oxygen Saturation With Ambulatory Function and Quality of Life in Symptomatic Patients With Peripheral Artery Disease

**Andrew W Gardner** , Polly S Montgomery, Ming Wang, Biyi Shen, Penn State Coll of Med, Hershey, PA

1:30 PM

Board # 4300

Platelet Activity and Major Adverse Limb Events in Patients With Symptomatic Peripheral Artery Disease Undergoing Lower Extremity Revascularization

**Gustavo Hernandez** , Crystalann Rodriguez, Angela Lee, Elliot Luttrell-Williams, New York Univ Sch Med, New York, NY; Michael A Nardi, NYULMC, New York, NY; Tessa Barrett, NYU Sch of Med, New York, NY; Yajaria Suarez, Glenn Jacobowitz, Yale Sch of Med, New Haven, CT; Thomas Maldonado, Judith S Hochman, NYU Sch of Med, New York, NY; Caron Rockman, Jeffrey S Berger, New York Univ Sch Med, New York, NY

1:30 PM

Board # 4301

Lung Function and Risk of Peripheral Artery Disease: The Atherosclerosis Risk in Communities Study

**Ning Ding** , Maya Salameh, Elizabeth Selvin, Johns Hopkins Univ, Baltimore, MD; Naresh M Punjabi, Baltimore, MD; Gerardo M Heiss, Univ North Carolina, Chapel Hill, NC; Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD

1:30 PM

Board # 4302

The Association of Disease Progression With Cardiovascular and Limb Outcomes in Patients With Peripheral Artery Disease: Insights From the EUCLID Trial

**Jennifer A Rymer** , Duke, Durham, NC; Hillary Mulder, Frank W Rockhold, Duke Clinical Res Inst, Durham, NC; William R. Hiatt, Univ of Colorado Sch Med, Aurora, CO; Francis G Fowkes, Univ of Edinburgh, Edinburgh, United Kingdom; Iris Baumgartner, Inselpital Angiuolgy Div, Bern; Jeffrey S Berger, New York Univ Sch Med, New York, NY; Brian Katona, Astra Zeneca LP, Gaithersburg, MD; Kenneth W Mahaffey, Stanford Univ, Stanford, CA; Lars Norgren, Örebro Univ, Sweden, Örebro, Sweden; Juuso Blomster, Univ of Turku, Turku, Finland; William S Jones, Duke Univ Medical Ctr, Durham, NC; Manesh R Patel, Duke Medical Ctr, Durham, NC

1:30 PM

Poster Professor

Aruna D Pradhan, Boston, MA

1:30 PM

Board # 4303

Home Monitoring in a Large Contemporary Real-World Atrial Fibrillation Population on Warfarin

**Martin van Zyl** , Thomas M Jaeger, Mayo Clinic, Rochester, MN; Waldemar E Wysokinski, Mayo Clinic, Rochester, Rochester, MN; Bernard J Gersh, Mayo Clinic, Rochester, MN; Robert D. McBane II, Mayo Clinic and Fndn, Rochester, MN

# Abstract Poster Session

## WS.APS.02 - Pregnancy and Female-Specific CVD Risk Factors

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3113

Trends and Outcomes of Acute Stroke During Pregnancy and Puerperium in the United States

**Islam Y Elgendy** , Massachusetts General Hosp, Boston, MA; Mohamed Gad, Cleveland Clinic, Cleveland, OH; Ahmed Mahmoud, Ellen Keeley, Carl Pepine, Univ of Florida, Gainesville, FL

1:30 PM

Board # 3114

Hypertensive Syndromes Predict Acute Myocardial Infarction During Pregnancy, Delivery, and Postpartum Periods: Insights From the National Inpatient Sample

**Courtney A Balgobin** , Xiaoyue Zhang, Stony Brook Sch of Med, Stony Brook, NY; Fabio V Lima, Brown Univ, Providence, RI; Puja B Parikh, Stony Brook Univ Medical Ctr, Stony Brook, NY; Jie Yang, Kathleen Stergiopoulos, Stony Brook Sch of Med, Stony Brook, NY

1:30 PM

Board # 3115

Echocardiographic Screening of Pregnant Women by Non-Physicians With Remote Interpretation in Primary Care: Data From the PROVAR+ Study

**Bruno R Nascimento** , Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Andrea Z Beaton, Cincinnati Childrens Hosp Medic, Cincinnati, OH; Maria Do Carmo Pereira Nunes, UFMG, Belo Horizonte, Brazil; Kaciane K Oliveira, Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Adriana C Diamantino, Rua Herculano De Freitas 151, Belo Horizonte Mg, Brazil; Lara C Rabelo, Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Marcia Barbosa, Hosp Socor, Belo Horizonte, Brazil; Alison T Reese, Children´s Natl Health System, Washington, DC; Susana P Reis, Clara L Fraga, Breno D Rezende, Waydder Antônio A Costa, Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Antonio L Ribeiro, UFMG, Belo Horizonte, Brazil; Craig A Sable, Children's Natl Medical Ctr, Potomac, MD

1:30 PM

Board # 3116

Real-world In-hospital Outcomes and Potential Predictors of Heart Failure in Pregnant Women With Heart Disease in Southwestern China

Wuwan Wang, Lu Wang, Panpan Feng, **Wei Huang** , The First Affiliated Hosp of Chongqing Medical Univ, Chongqing, China

1:30 PM

Board # 3117

Ideal Cardiovascular Health According to Preeclampsia History: Opportunities to Improve Preventative Care

**Jennifer Lewey** , Clare McCarthy, Obe B Ibe, Michal A Elovitz, Lisa Levine, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 3119

Uterine Fibroids Affect the Harmonic Characteristics of Radial Pulse Waves

Chih-Yu Chen, Renai Branch of Taipei City Hosp, Taipei, Taiwan; **Chi-Wei Chang** , Mii-Ann Medical Ctr, Taipei, Taiwan; Yi-Ting Chang, Johns Hopkins Bloomberg Sch of Public Health,, Baltimore, MD; Sheng-Hung Wang, Mii-Ann Medical Ctr, Taipei, Taiwan; gin-chung wang, JinMu Health Technology, Taipei, Taiwan

1:30 PM

Board # 3120

Associations Between Urinary Isoprostane Levels and Menopausal Status in the Coronary Artery Risk Development in Young Adults (CARDIA) Study

**Amir S Heravi** , Dhananjay Vaidya, Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD; Di Zhao, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Bharath Ambale-Venkatesh, Henrique Doria De Vasconcellos, Johns Hopkins Sch of Med, Baltimore, MD; Donald M Lloyd-jones, Northwestern Univ, Chicago, IL; Pamela Schreiner, Univ of Minnesota, Minneapolis, MN; Jared P Reis, Natl Inst of Health, Bethesda, MD; Cora E Lewis, Univ of Alabama at Birmingham, Birmingham, AL; Stephen Sidney, Kaiser Permanente Medical Care, Oakland, CA; Colin Wu, Natl Insts of Health, Bethesda, MD; Chiadi E Ndumele, Johns Hopkins Sch of Med, Baltimore, MD; Eliseo Guallar, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Pamela Ouyang, Johns Hopkins Sch of Med, Baltimore, MD; Ron C Hoogeveen, Baylor Coll of Med, Houston, TX; Joao A Lima, Wendy S Post, Johns Hopkins Sch of Med, Baltimore, MD

1:30 PM

Board # 3121

GSNOR Deficiency Causes Aberrant Placental S-nitrosylation and Preeclampsia

**Shathiyah Kulandavelu** , Univ Miami Miller Sch Med, Miami, FL; Raul A Dulce, Interdisciplinary Stem Cell Inst, Miami, FL; Christopher I Murray, Cedars-Sinai Medical Ctr, Los Angeles, CA; Wayne Balkan, Univ Miami Miller Sch, Miami, FL; Jennifer E Van Eyk, Cedar Sinai Medical Ctr, Los Angeles, CA; Joshua M Hare, Univ of Miami, Miami, FL

1:30 PM

Board # 3122

Associations of Maternal Lipid and Apolipoprotein Levels in Pregnancy With Offspring Lipid Levels in Childhood: The Hyperglycemia and Adverse Pregnancy Outcome Follow up Study

**Amanda Marma Perak** , Alan Kuang, Nicola Lancki, Darwin R Labarthe, Northwestern Univ, Chicago, IL; Svati H Shah, Duke Univ, Durham, NC; Lynn P Lowe, William L Lowe Jr, Donald M Lloyd-Jones, Denise M Scholtens, Northwestern Univ, Chicago, IL; for the HAPO Follow-Up Study Cooperative ResearchGroup

1:30 PM

Poster Professor

Monika Sanghavi, Philadelphia, PA

# Abstract Poster Session

## PH.APS.03 - Pulmonary Hypertension: Group 1 and Beyond

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2231

Association Between Positive End-Expiratory Pressure With Mortality and Mechanical Ventilation Duration in Patients With Left and Right Ventricular Dysfunction: Insights From the Medical Information Mart for Intensive Care (MIMIC-III) Database

Albert Y Lui, New York Univ Medical Sch, New York, NY; Leonid Garber, New York Univ Langone Health, New York, NY; Christopher Cosgriff, New York Univ Medical Sch, New York, NY; Vincent J Major, New York Univ, New York, NY; Jordan Poles, New York Univ Medical Sch, New York, NY; Marie Charpignon, MIT, Cambridge, MA; Leo A Celi, Beth Israel Deaconess Medical Ctr, Boston, MA; Sean Van Diepen, Univ of Alberta, Edmonton, AB, Canada; Nathaniel Smilowitz, NYU Sch of Med, New York, NY; **Carlos L Alviar** , New York Univ, New York, NY

1:30 PM

Board # 2232

Evolution of Human Pulmonary Hemodynamics During Severe Sustained Hypoxia

**Fabian Hoffmann** , German Aerospace Ctr, Cologne, Germany; Ulrich Limper, Cologne-Merheim Medical Ctr, Univ of Witten Herdecke, Cologne, Germany; Vlad G Zaha, UT Southwestern Medical Ctr, Dallas, TX; Hannes Reuter, Univ of Cologne, Cologne; Jeanette Schulz-Menger, Leonora Zange, Experimental and Clinical Res Ctr, Berlin, Germany; Marc Hein, RWTH Univ Hosp AachenGerman Aerospace Ctr, Aachen, Germany; Hesham A Sadek, UT Southwestern Medical Ctr, Dallas, TX; Stephan Baldus, Univ Hosp Cologne, Cologne; Benjamin D Levine, UT Southwestern Medical Ctr, Dallas, TX; Jens Jordan, German Aerospace Ctr, Cologne; Jens Tank, German Aerospace Ctr, Cologne, Germany

1:30 PM

Board # 2233

Role of Mechanical Circulatory Support Devices in Patient With Pulmonary Hypertension and STEMI

**Ahmad Armoghan Yousuf Awan** , Howard Univ Hosp, Washington, DC; Muhammad Rizwan, Richard Ogunti, Howard Univ Hosp, washington, DC; Mohammad Mohsin Munawwar, Manila Jindal, Isaac Opoku-Asare, Howard Univ Hosp, Washington, DC

1:30 PM

Board # 2234

Outcomes of Pulmonary Arterial Hypertension are Improved in a Specialty Care Center

Hongyang Pi, **Chad Kosanovich** , Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Adam Handen, Pittsburgh Heart, Lung, Blood, and Vascular Med Inst, Pittsburgh, PA; Michael Tao, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Jacqueline Visina, Univ of Pittsburgh Sch of Med, Pittsburgh, PA; Gabrielle VanSpeybroeck, Mehdi Nouraie, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Stephen Y Chan, Univ of Pittsburgh, Pittsburgh, PA

1:30 PM

Board # 2235

E-vaping Induces Pulmonary Arterial Hypertension via Pathological Remodeling in the Lungs and Right Heart

Matthew Peterson, **Yohannes Getiye Estifanos** , Shaonil Binti, Olivia Glassock, Alyssa Sanders, Aspen Smith, Luiza Bosch, Guanglong He, Univ of Wyoming, Laramie, WY

1:30 PM

Board # 2236

Impact of Co-Existing Chronic Obstructive Pulmonary Disease versus Obesity Hypoventilation Syndrome (Pickwickian Syndrome) on In-Hospital Outcomes of Percutaneous Coronary Interventions in Patients With Obstructive Sleep Apnea

Rupak Desai, Atlanta VA Medical Ctr, Decatur, GA; Upenkumar Patel, Nassau Univ Medical Ctr, East Meadow, NY; **Rushik Bhuva** , Geisinger Wyoming Valley Medical Ctr, Wilkes-Barre, PA; Tarang Parekh, George Mason Univ, Fairfax, VA; Sonu Gupta, Morehouse Sch of Med, Atlanta, GA; Yash Varma, Guthrie Robert Packer Hosp, Sayre, PA; Muhammad Uzair Lodhi, Eastern Idaho Regional Med Ctr, Idaho Falls, ID; Mir Zeeshan Ali Khan, St. Peters Univ Hosp, New Brunswick, NJ; Nazia Farheen, Lake America Family Physicians, Clermont, FL; Rajesh Sachdeva, Morehouse Sch of Med & Atlanta VA Medical Ctr, Atlanta, GA; Gautam Kumar, Emory Univ, Decatur, GA

1:30 PM

Board # 2237

The Impact of Increased Pulmonary Arterial Pressure on Outcomes After Transcatheter Aortic Valve Replacement

Satoru Osaki, Giorgio Gimelli, Amish N Raval, Kurt M Jacobson, Matthew R Wolff, **Kosuke Ujihira** , Univ of Wisconsin, Madison, WI

1:30 PM

Board # 2238

Risk Factors for Obstructive Sleep Apnea in Patients With Pulmonary Hypertension

**Kayvon Ghoreshi** , Noura Alturaif, Robert Roth, Yeilim Cho, Christopher Harding, Nishaki M Mehta, Eric Davis, Andrew Mihalek, Sula Mazimba, Younghoon Kwon, Univ of Virginia, Charlottesville, VA

1:30 PM

Board # 2239

Genetic Admixture and Survival in Diverse Populations With Pulmonary Arterial Hypertension (PAH)

**Jason Hansen Karnes** , Univ of Arizona, Tucson, AZ; Howard Wiener, Univ of Alabama-Birmingham, Birmingham, AL; Tae-Hwi Schwantes-An, Indiana Univ, Indianapolis, IN; Balaji Natarajan, UC Riverside Sch of Med, Sn Bernrdno, CA; Abhishek Chaturvedi, Allegheny General Hosp, Pittsburg, PA; Amit H Arora, Ken Batai, Vineet Nair, Heidi Steiner, Jason Giles, Jeffrey Yu, Maryam Hosseini, Univ of Arizona, Tucson, AZ; Michael Pauciulo, Children's Hosp Medical Ctr Cincinnati, Cincinnati, OH; Katie Lutz, Anna Coleman, Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; Jeremy Feldman, Arizona Pulmonary Specialists, Phoenix, AZ; Rebecca Vanderpool, Haiyang Tang, Joe Garcia, Univ of Arizona, Tucson, AZ; Jason Yuan, Univ of California, San Diego, La Jolla, CA; Franz Rischard, The Univ of Arizona, Tucson, AZ; Rick Kittles, City of Hope, Los Angeles, CA; Hemant K Tiwari, Univ of Alabama at Birmingham, Birmingham, AL; Bill Nichols, Univ of Alabama at Birmingham, Birmingham, AL, Cincinnati; Raymond Benza, Allegheny Health Network, Pittsburgh, PA; Ankit Desai, Indiana Univ, Indianapolis, IN

1:30 PM

Board # 2240

Intervening With the Nitric Oxide Pathway to Alleviate Pulmonary Hypertension in Pulmonary Vein Stenosis

**Daphne Merkus** , Richard WB van Duin, Kelly Stam, AH Jan Danser, Dirk J. Duncker, Erasmus MC, Rotterdam, Netherlands

1:30 PM

Poster Professor

Thenappan Thenappan, Minneapolis, MN

# Abstract Poster Session

## QU.APS.01 - Quality of Care and Outcomes Research

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3211

Predictors of 30-day Readmissions After Cardiac Surgery

**Samantha Hall** , Carilion Clinic, Radford Univ, Roanoke, VA; Cathy D Jennings, Carilion Clinic, Blue Ridge, VA; Ellen Rachel Lockhart, Carilion Clinic, Roanoke, VA; Eunyoung Lee, Radford Univ, Blacksburg, VA

1:30 PM

Board # 3213

Preference of Individuals in the Treatment Strategies of Acute Myocardial Infarction in China: A Discrete Choice Experiment

**Weiqian Dai** , Chang Liu, Yaduan Lin, Jiahe Liu, Yu Cheng, Wing Hei Tsang, Wai Kit Ming, Jinan Univ, Guangzhou, China

1:30 PM

Board # 3214

Lipid Monitoring and Treatment Intensification of Cholesterol Lowering Therapies - Insight From the Veterans Affairs Healthcare System

**Xiaoming Jia** , David J Ramsey, Baylor Coll of Med, Houston, TX; Mahmoud al Rifai, Univ of Kansas Sch of Med, Wichita, KS; Sarah T Ahmed, Julia M Akeroyd, Baylor Coll of Med, Houston, TX; Dave L Dixon, Virginia Commonwealth Univ, N Chesterfld, VA; Ty Gluckman, Providence St. Joseph Health, Portland, OR; VIJAY NAMBI, Christie M Ballantyne, Laura A Petersen, Baylor Coll of Med, Houston, TX; Neil J Stone, Feinberg Sch of Med, Chciago, IL; Salim S Virani, Michael E Debakey VA-Baylor, Bellaire, TX

1:30 PM

Board # 3215

Discharge Disposition Significantly Impacts Quality Assessment

**Lauren Gray Gilstrap** , Dartmouth Hitchcock Medical Ctr, Lebanon, NH; Andrea M Austin, The Dartmouth Inst, Lebanon, NH; Barbara Gladders, Dartmouth Hitchcock Medical Ctr, Lebanon, NH; James O'Malley, Amber Barnato, Anna Tosteson, Jonathan S. Skinner, The Dartmouth Inst, Lebanon, NH

1:30 PM

Board # 3216

A Novel Patient Reported Outcome Questionnaire for Reduction in Heart-Failure Readmissions: Protocol for Usability Assessment Study

Rashmi Aggarwal, **Alexis K Okoh** , Matthew Shreiber, RWJ Barnabas Health NBIMC, Newark, NJ

1:30 PM

Board # 3217

Relationship Between a Hospital's 30-Day Readmission and Mortality Rates of Patients With Heart Failure and Hospital's Rating by Patients

**Nargiza Kurbanova** , Rehan Qayyum, Virginia Commonwealth Univ, Richmond, VA

1:30 PM

Board # 3218

Long-term Clinical Outcomes of Long Coronary Lesions in Acute Myocardial Infarction Patients Underwent Percutaneous Coronary Intervention

**Seung Woon Rha** , Kareem Abdelshafi, Byoung Geol Choi, Se Yeon Choi, Jae Kyeong Byun, Jinah Cha, Yoonjee Park, Dong Oh Kang, Won-Young Jang, Woohyeun Kim, Jah Yeon Choi, Jin Oh Na, Cheol Ung Choi, Chang Gyu Park, Hong-Seog Seo, Korea Univ Guro Hosp, Seoul, Korea, Republic of

1:30 PM

Board # 3219

Sydney Device Study: A Multicenter, Randomized, Open-label Usability Study of a New 2 Ml Alirocumab Autoinjector Device

**Juan Pablo Frias** , Natl Res Inst, Los Angeles, CA; Michael J Koren, Jacksonville Ctr for Clinical Res, Jacksonville, FL; Virginie Loizeau, Ana Merino-Trigo, Sanofi, Chilly-Mazarin, France; Michael J Louie, Mary Alice Raudenbush, Regeneron Pharmaceuticals, Inc., Tarrytown, NY; Isabela A Batsu, Sanofi, Bridgewater, NJ

1:30 PM

Board # 3220

Risk of Sudden Death and Malignant Neoplasia in Patients After Acute Coronary Syndrome (20 Years of Follow Up). The ABC Study on Acute Coronary Syndrome

**Giuseppe Berton** , Conegliano General Hosp, Conegliano, Italy; Heba T Mahmoud, The ABC Heart Disease Fndn, Conegliano, Italy; Palmieri Rosa, Adria General Hosp, Adria, Italy; Fiorella Cavuto, Bassano del grappa General Hosp., Bassano del grappa, Italy; Rocco Cordiano, Adria General Hosp, Adria, Italy; Francesco Bagato, Feltre General Hosp., Feltre, Italy; Elisabetta Lorenzon, The ABC Heart Disease Fndn, Conegliano, Italy; Moemen M Mahmoud, Minia Univ Hosp, Minia, Egypt; Arianna Cati, Conegliano General Hosp, Conegliano, Italy

1:30 PM

Board # 3221

Why Are Patients Readmitted to the Hospital After an Acute Myocardial Infarction?

**Raunak Nair** , Cleveland Clinic Fairview Hosp, Cleveland, OH; Mouin S Abdallah, Chetan Huded, Michael Johnson, Kathleen Ann Kravitz, Newton Wiggins, Moses Anabila, Jeevanantham Rajeswaran, Eugene H Blackstone, Venu Menon, A Michael Michael Lincoff, Samir R Kapadia, Umesh Khot, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 3222

Risk of Sudden and Non Sudden Cardiac Death in Patients Long After Acute Coronary Syndrome, the Value of Hypertension and Albuminuria. The ABC Study on Acute Coronary Syndrome

Heba T Mahmoud, The ABC Heart Disease Fndn, Conegliano, Italy; **Giuseppe Berton** , Conegliano General Hosp, Conegliano, Italy; Rosa Palmieri, Adria General Hosp, Adria, Italy; Francesco Bagato, Feltre General Hosp., Feltre, Italy; Rocco Cordiano, Adria General Hosp, Adria, Italy; Fiorella Cavuto, Bassano del grappa General Hosp., Bassano del grappa, Italy; Elisabetta Lorenzon, The ABC Heart Disease Fndn, Conegliano, Italy; Moemen M Mahmoud, Minia Univ Hosp, Minia, Egypt; Gerlando Preti, Conegliano general hospital, Conegliano, Italy

1:30 PM

Board # 3223

Changes Over Time in Serum Albumin Levels Predict Outcomes Following Percutaneous Coronary Intervention

**Arthur Shiyovich** , Tamir Bental, Rabin Medical Ctr, Petah Tikva, Israel; Abid R Assali, Rain Medical Ctr, Belinson, KFAR-QARA, Israel; Hana Vaknin-Assa, Rabin Medical Ctr, Petah Tikva, Israel; Ran Kornowski, Rabin Medical Ctr, Israel, Petach Tikva, Israel; Leor Perl, Rabin Medical Ctr, Petah Tikva, Israel

# Abstract Poster Session

## AT.APS.02 - Redox Signaling and Cardiovascular Disease

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1031

Increased Dipeptidyl Peptidase-4 Accelerates Chronic Stress-related Thrombosis in Mouse Carotid Artery Model

**Xianglan Jin** , Chunzi Jin, Minglong Xin, Ying Wan, Xueling Yue, Xian Wu Cheng, Yanbian Univ Hosp, Yanji, China

1:30 PM

Board # 1032

Oxidative Stress Regulates the Phenotype of Vascular Smooth Muscle Cells via Promoting Drp1-Mediated Mitochondrial Fission

**Zifang Song** , Wei Li, Xiaowei Tang, Qihong Yu, Union Hosp, Tongji Medical Coll, HUST, Wuhan, China

1:30 PM

Board # 1033

Glutaredoxin1 Preserves Endoplasmic Reticulum Stress Response in Aortic Endothelium in Aging

Tomoko Mori, Yuxiang Zhou, **Jingyan Han** , Boston Univ, Boston, MA

1:30 PM

Board # 1034

Tea Domain Family Member 1 (TEAD1): Novel Role in Regulating Cardiac Oxidative Stress Response

**Rajaganapathi Jagannathan** , Ruya Liu, Jeongkyung Lee, Evan R DeVallance, Ping Yang, Feng Li, Vinny Negi, Patrick J Pagano, Vijay K Yechoor, Moulik Mousumi, Univ of Pittsburgh, Pittsburgh, PA

1:30 PM

Board # 1035

The Incorporation of Oxidation Resistant ApoA1-4WF in Adeno-Associated Viral and Lentiviral Gene Vectors With Robust Cholesterol Efflux in vitro

**Benjamin B Pressly** , Bahman Hooshdaran, Ivan S Alferiev, Philip Zoltick, Children's Hosp of Philadelphia, Philadelphia, PA; Robert L Wilensky, Univ Pennsylvania, Philadelphia, PA; Robert Gorman, Perelman Sch of Med Univ of Pennsylvania, Philadelphia, PA; Jonathan D Smith, Stanley L Hazen, Cleveland Clinic Fndn, Cleveland, OH; Robert Levy, Ilia Fishbein, Children's Hosp of Philadelphia, Philadelphia, PA

1:30 PM

Board # 1036

Oxidized-phospholipid Mediated Ischemia-reperfusion Injury and Its Mitigation by IL-10

**Ashim K Bagchi** , Arun Surendran, Akshi Malik, Amir Ravandi, Davinder S Jassal, Pawan K Singal, St. Boniface Hosp. Res Ctr, Winnipeg, MB, Canada

1:30 PM

Board # 1037

Cu Importer CTR1 is a Redox Sensor That Promotes VEGFR2 Signaling and Angiogenesis

**Archita Das** , Dipankar Ash, Young-Mee Kim, Sudhahar Varadarajan, Yali Hou, Farlyn Z Hudson, Brian K Stansfield, Med. Coll. of Georgia at Augusta Univ, Augusta, GA; Jack Kaplan, Univ of Illinois at Chicago, Chicago, IL; Tohru Fukai, Masuko Ushio-Fukai, Med. Coll. of Georgia at Augusta Univ, Augusta, GA

1:30 PM

Board # 1039

Oral Pretreatment With RTA Dh404 Decreased Oxidative Stress in Ischemic Limbs of Mice and Augmented Efficacies of Therapeutic Angiogenesis by an Intramuscular Injection of Adipose-Derived Regenerative Cells in the Limbs

**Yuta Ishizaki** , Ken-ichiro Sasaki, Takafumi Ueno, Kurume Univ Hosp, Fukuoka, Japan; Colin J Meyer, Joel W Proksch, Reata Pharmaceuticals, Irving, TX; Takaharu Nakayoshi, Kurume Univ Hosp, Fukuoka, Japan; Masanori Ohtsuka, Motoki Sasaki, Sachiko Katakabe, Takahito Yoshikawa, Naoki Itaya, Hidetoshi Tibana, Masahiro Sasaki,, Takashi Ishimatsu, Kohtaro Kagiyama, Yuki Takata, Kazunori Yamaji, Kurume Univ Hosp, Fukuoka, Japan; Yoshihiro Fukumoto, Kurume Univ Sch Hosp, Kurume, Japan

1:30 PM

Board # 1040

**P66** Shc **Signaling Pathway in the Heart Subjected to Ischemia/reperfusion Injury**

**Huamei He** , Brigham and Women's Hosp, HMS, Boston, MA; Hui Xiong, Jiangxi Health Vocational Coll, Nanchang, China; Francis X McGowan Jr., Children's Hosp of Philadelphia, Philadelphia, PA

1:30 PM

Board # 1041

Fibrin Gel Embedding Adipose-derived Mesenchymal Stem Cell Showed Therapeutic Effect Against Rat Ischemic Cardiomyopathy by Enhancement in Nox Synthesis

**Daisuke Mori** , Shigeru Miyagawa, Takuji Kawamura, Hiroki Hata, Takayoshi Ueno, Koichi Toda, Kotoe Kawai, Hayato Kurata, Hiroyuki Nishida, Yoshiki Sawa, Osaka Univ, Suita, Japan

1:30 PM

Board # 1042

Ultrasound Treatment Improves Myocardial Blood Flow and Wall Thickening After Acute Myocardial Infarction

**Dai-Trang Elizabeth Le** , VA Portland Health Care System, Portland, OR; Brian Mott, Azzdine Y Ammi, Igor Dykan, Mrinal Yadava, Yan Zhao, Matthew Nugent, Oregon Health and Science Univ, Portland, OR; Jessica Minnier, Sanjiv Kaul, Oregon Health and Science Univeristy, Portland, OR

# Abstract Poster Session

## CH.APS.04 - Risk Assessment in Adults with Tetralogy of Fallot Beyond Right Ventricular Size

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4068

Left Ventricular Systolic Dysfunction and Cardiovascular Outcomes in Tetralogy of Fallot: A Systematic Review and Meta-analysis

**Alexander C Egbe** , Mayo Clinic, Rochester, MN

1:30 PM

Board # 4069

Levels of Fib-4 as Hepatic Fibrosis Marker Elevated to React High Right-sided Pressures in Adult Patients With Tetralogy of Fallot After Definitive Repair

**Yuji Hamamichi** , Sakakibara Heart Inst, Tokyo, Japan; Akio Inage, Sakakibara Heart Inst, Toronto, ON, Canada; Yoshimasa Maeda, Tomomi Ueda, Satoshi Yazaki, Tadahiro Yoshikawa, Sakakibara Heart Inst, Tokyo, Japan

1:30 PM

Board # 4070

Identification of Optimal Timing for Pulmonary Valve Replacement in Asymptomatic Repaired Tetralogy of Fallot Using Feature Tracking

**Akio Inage** , Kanako Kishiki, Ryusuke Suzuki, Naokazu Mizuno, Sakakibara Heart Inst, Tokyo, Japan

1:30 PM

Board # 4071

High Prevalence of Inappropriate Shocks in Tetralogy of Fallot Patients With Implantable Cardioverter Defibrillators: 20-year Experience of a Large Academic Institution

**Isaac Goldenthal** , Columbia Univ Irving Medical Ctr, New York, NY; Marlon S Rosenbaum, Columbia Univ, New York, NY; Hasan Garan, New York Presbyterian Medical Ctr, New York, NY; Angelo B Biviano, Columbia Univ Medical Ctr, New York, NY

1:30 PM

Board # 4072

Analysis of Risk Factors for Progression of Aortic Regurgitation in Adults Late After Repair of Tetralogy of Fallot

**Takuji Watanabe** , Takayoshi Ueno, Tomomitsu Kanaya, Naoki Okuda, Kanta Araki, Yuji Tominaga, Koichi Toda, Toru Kuratani, Yoshiki Sawa, Osaka Univ Graduate Sch of Med, Suita, Japan

1:30 PM

Board # 4073

Assessment of Right Ventricular Reserve in Adult Patients With Tetralogy of Fallot

**Christopher W Valle** , Jaclyn Pagliaro, Mark Schoenike, Christopher Philip Learn, Ami Bhatt, Gregory Lewis, Doreen DeFaria Yeh, Massachusetts General Hosp, Boston, MA

1:30 PM

Board # 4074

Cardiac Magnetic Resonance Predictors of Adverse Outcomes in Tetralogy of Fallot: Lessons From the Single Center Outcomes Study in Tetralogy of Fallot (SCOUT-TOF)

**Mark Alan Fogel** , Quynh Tran, Jennifer Faerber, Antara Mondal, Childrens Hosp of Philadelphia, Philadelphia, PA; Xuemei Zhang, Kevin K Whitehead, Matthew A Harris, Children's Hosp of Philadelphia, Philadelphia, PA; Sara Partington, Children's Hosp of Philadelpia, Philadelphia, PA; David M Biko, Children's Hosp of Phladelphia, Philadelphia, PA; Laura A Mercer-Rosa, Children's Hosp of Philadelphia, Philadelphia, PA

1:30 PM

Board # 4075

Prevalence and In-hospital Mortality During Arrhythmia-related Admissions in Adults With Tetralogy of Fallot

**Alexander C Egbe** , Mayo Clinic, Rochester, MN

1:30 PM

Board # 4076

Prognostic Implications of Left Ventricular Cardiomyopathy in Adults With Tetralogy of Fallot

**Alexander C Egbe** , Mayo Clinic, Rochester, MN

1:30 PM

Board # 4077

Left Ventricular Filling Pressure in Tetralogy of Fallot: Correlation Between Invasive and Noninvasive Indices

**Alexander C Egbe** , Mayo Clinic, Rochester, MN

1:30 PM

Poster Professor

Rachel Maya Wald, Toronto, ON, Canada

# Abstract Poster Session

## LF.APS.01 - Social, Behavioral and Occupational Determinants of Cardiometabolic Health

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3164

Academic Bullying in Medicine: A Systematic Review

**Tauben Averbuch** , Yousif Eliya, Harriette GC Van Spall, McMaster Univ, Hamilton, ON, Canada

1:30 PM

Board # 3165

Annual Screening and Digital Behavioral Counseling in a Workplace Setting Reduce 10-year Cardiovascular Risk

**Olga Iakoubova** , Robert J Lagier, Maren S Fragala, Quest Diagnostics Nichols Inst, San Juan Capistrano, CA; Kelsey McNamara, Cynthia M Castro Sweet, Omada Health, San Francisco, CA; Charles E Birse, Quest Diagnostics Nichols Inst, San Juan Capistrano, CA

1:30 PM

Board # 3166

Perceived Benefits Of Natural Residential Greenness Are Associated With Healthier Cardiovascular Lifestyles

**Alok R Amraotkar** , Rachel J Keith, Daniel W Riggs, Joy L Hart, Kandi L Walker, Sanjay Srivastava, Aruni Bhatnagar, Univ of Louisville, Louisville, KY

1:30 PM

Board # 3167

High Blood Selenium Concentrations Are Associated With Atherogenic Lipoprotein Cholesterol in US Adolescents and Adults From 2011-2016 National Health and Nutrition Examination Survey

**Jiayi Yi** , Yuanlin Guo, Xin Zheng, Fuwai Hosp, Beijing, China

1:30 PM

Board # 3168

Measures of Poor Sleep Quality are Associated With Higher Intakes of Added Sugars and Energy in Women From the go Red for Women Strategically Focused Research Network

**Faris Michael Zuraikat** , Columbia Univ Irving Medical Ctr, New York, NY; Nour Makarem, Columbia Univ Medical Ctr, New York, NY; Marie-Pierre St-Onge, Columbia Univ, New York, NY; Ming Liao, Columbia Univ Irving Medical Ctr, NEW YORK, NY; Brooke A Aggarwal, Columbia Univ Medical Ctr, New York, NY

1:30 PM

Board # 3169

The Usefulness of Geriatric Nutritional Risk Index as a Short Term Cardiovascular Prognostic Indicator in Elderly Dialysis Patients

**Akihiro Tokushige** , Yoshiyuki Ikeda, Daisuke Kanda, Ippei Kosedo, Akiko Yoshikawa, Kagoshima Univ, Kagoshima, Japan; Masakazu Imamura, Nanpuh Hosp, Kagoshima, Japan; Mitsuru Ohishi, Kagoshima Univ, Kagoshima, Japan

1:30 PM

Board # 3171

Impact of a Nurse-Led Limited Risk Factor Modification Program on Arrhythmia Outcomes in Patients With Medically Managed Atrial Fibrillation

**Amaryah Yaeger** , Brendan T. Keenan, Nancy R. Cash, Tara Parham, David S. Frankel, Rajat Deo, Robert D. Schaller, Pasquale Santangeli, Saman Nazarian, Gregory E. Supple, Jeffrey Arkles, Ramanan Kumareswaran, Matthew C. Hyman, Michael P. Riley, Fermin C. Garcia, David Lin, Andrew E. Epstein, David J. Callans, Francis E. Marchlinski, Jorge I. Mora, Anastassia Amaro, Richard Schwab, Allan Pack, Sanjay Dixit, Hosp of the Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 3172

Advancing People of Color in Clinical Trials (ACT Now!): A Culturally Tailored Web-Based Randomized Controlled Trial

**Alicia Chung** , Azizi Seixas, Natasha Williams, Joseph Ravenell, Girardin Jean-Louis, NYU Sch of Med, New York, NY

1:30 PM

Board # 3173

Sleep, Blood Pressure Variability, and Cardiovascular Outcomes

**Soojung Ahn** , Younghoon Kwon, Jeongok Logan, Jennifer M Lobo, Univ of Virginia, Charlottesville, VA; Hyojung Kang, Univ of Illinois at Urbana-Champain, Champaign, IL; Min-Woong Sohn, Univ of Virginia, Charlottesville, VA

# Abstract Poster Session

## CM.APS.01 - Strategies for Predicting and Reducing Risk in Diabetes and Prediabetes

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3000

Incidence of Hospitalization for ACS or Coronary Revascularization in Patients With Type 2 Diabetes Treated With Once Weekly GLP-1 Receptor Agonist Exenatide

**Carlos Barbery** , Duke Univ Hosp, Durham, NC; Jennifer White, Duke Univ Sch of Med, Durham, NC; Yuliya Lokhnygina, Duke Univ Medical Ctr, Durham, NC; Robert John Mentz, Adrian F Hernandez, Duke Univ Sch of Med, Durham, NC; Rury Holman, Univ of Oxford, Oxford; William S Jones, Duke Univ Medical Ctr, Durham, NC

1:30 PM

Board # 3001

Cost-Effectiveness Analysis of Empagliflozin as a Second-Line Therapy in Treatment Sequences of Patients With Type 2 Diabetes in The United States

Odette Reifsnider, Anuraag Kansal, Evidera, Bethesda, MD; **Pratik Pimple** , Boehringer Ingelheim Pharmaceutical, Ridgefield, CT; Valerie Aponte-Ribero, Evidera, Hammersmith, United Kingdom; Sarah Brand, Evidera, Bethesda, MD; Sharash Shetty, Boehringer Ingelheim Pharmaceuticals Inc, Ridgefield, CT

1:30 PM

Board # 3002

Alarmingly Rising Trends in Cardiovascular Events and Worsening Outcomes Among Adult Hospitalizations With Prediabetes

**Upenkumar Patel** , Nassau Univ Medical Ctr, East Meadow, NY; Tarang Parekh, George Mason Univ, Fairfax, VA; Sandeep Singh, Amsterdam Univ Medical Ctr, Amsterdam; Kishorbhai Gangani, Texas Health Arlington Memorial, Arlington, TX; Rupak Desai, Atlanta VA Medical Ctr, Decatur, GA

1:30 PM

Board # 3003

Accelerometer-Assessed Physical Activity and Risk of Incident Diabetes and Weight Change: The Hispanic Community Health Study/Study of Latinos

**Guo-Chong Chen** , Simin Hua, Jee-Young Moon, Albert Einstein Coll of Med, Bronx, NY; Nicole L Spartano, Ramachandran S. Vasan, Boston Univ, Boston, MA; Daniela Sotres-Alvarez, Univ of North Carolina at Chapel Hill, Chapel Hill, NC; Sheila F. Castaneda, San Diego State Univ, San Diego, CA; Kelly R Evenson, Krista Perreira M. Perreira, Univ of North Carolina at Chapel Hill, Chapel Hill, NC; Linda C. Gallo, San Diego State Univ, San Diego, CA; Amber Pirzada, Martha L. Daviglus, Univ of Illinois at Chicago, Chicago, IL; Marc D. Gellman, Univ of Miami, Miami, FL; Robert Kaplan, Xiaonan Xue, Yasmin Mossavar-Rahmani, Qibin Qi, Albert Einstein Coll of Med, Bronx, NY

1:30 PM

Board # 3004

Development and Validation of New Cardiovascular Disease Risk Scores for Patients With Diabetes Mellitus From a Pooled Cohort of the US Population

Yanglu Zhao, Univ of California, Los Angeles, Los Angeles, CA; Ralph B D'Agostino Sr., Boston Univ, Boston, MA; Alain G Bertoni, Wake Forest Univ Sch Med, Winston Salem, NC; Matthew J Budoff, Los Angeles Biomedical Res, Torrance, CA; Adolfo Correa, Univ of Mississippi Medical Ctr, Jackson, MS; Aaron Folsom, David R. Jacobs Jr., Univ of Minnesota, Minneapolis, MN; Shaista Malik, Univ of California, Irvine, Irvine, CA; Elizabeth Selvin, Johns Hopkins Univeristy, Baltimore, MD; Karol E. Watson, Univ of California, Los Angeles, Los Angeles, CA; **Nathan D Wong** , Univ of California Irvine, Irvine, CA

1:30 PM

Board # 3005

Achieving Guideline-Directed Therapy in U.S. Patients With Diabetes and Cardiovascular Disease: Alarming Gaps, Compelling Opportunities

**Maddalena Ardissino** , Adam J Nelson, Duke Clinical Res Inst, Durham, NC; Kevin Haynes, Zubin Eapen, Sonali Shambhu, HealthCore, Wilmington, DE; Anthony Carnicelli, Emily C O'Brien, Renato D Lopes, Jennifer Green, Duke Clinical Res Inst, Durham, NC; Darren K McGuire, Univ Texas Southwestern Med Ctr, Dallas, TX; Neha Pagidipati, Duke Univ Medical Ctr, Durham, NC; Christopher Bull Granger, Duke Clinical Res Inst, Durham, NC

1:30 PM

Board # 3006

Severity of Diastolic Dysfunction and Long-Term Clinical Outcomes in Diabetic versus Non-Diabetic Patients Hospitalized for Acute Heart Failure: A Population Based Study

**Siu-Hin Wan** , Joshua P Slusser, David O Hodge, Horng Chen, Mayo Clinic, Rochester, MN

1:30 PM

Board # 3007

Circulating Pcsk9 Levels Are Not Associated With the Conversion to Type 2 Diabetes

**Stephane Ramin-Mangata** , Lab UMR DéTROI, Sainte Clotilde, Réunion; Gilles Lambert, Lab Inserm UMR DéTROI, Sainte Clotilde, Réunion

1:30 PM

Board # 3008

QRS Duration is Associated With All-Cause Mortality in Type 2 Diabetics: The Diabetes Heart Study

**Matthew J Singleton** , Wake Forest Sch of Med, Winston-Salem, NC; Charles German, Wake Forest Baptist Medical Ctr, Winston Salem, NC; Krupal Hari, Georgia Saylor, Wake Forest Sch of Med, Winston-Salem, NC; David M Herrington, Wake Forest Univ Sch Medici, Winston Salem, NC; Elsayed Z Soliman, Barry Freedman, Wake Forest Sch of Med, Winston Salem, NC; Donald Bowden, Wake Forest Sch of Med, Winston-Salem, NC; Prashant Bhave, Wake Forest Sch of Med, Winston Salem, NC; Joseph Yeboah, Wake Forest Univ, Winston Salem, NC

1:30 PM

Board # 3009

Metformin is Associated With Lower Rates of Cardiovascular Complications After Myocardial Infarction - A Report From the Swedeheart Registry

**Viveca Ritsinger** , Cardiology Unit, Stockholm, Sweden; Bo Lagerqvist, Dept of Medical Sciences, Cardiology, Uppsala, Sweden; Anna Norhammar, Cardiology Unit, Stockholm, Sweden

1:30 PM

Poster Professor

Mercedes R Carnethon, Chicago, IL

# Abstract Poster Session

## ST.APS.03 - Stroke Abstracts

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2328

Actimis Trial: Safety and Efficacy Evaluation of ACT017, a Novel Antiplatelet Agent on Top of Acute Ischemic Stroke Standard of Care

Mikael Mazighi, Fondation Rothschild, Paris, France; Yannick Pletan, **Andrea Comenducci** , Hop Bichat, Paris, France; Bertrand Lapergue, Hop Foch, Suresnes, France; Danilo Toni, Univ Rome Sapienza, Rome, Italy; Martin Koehrmann, Univ Hosp Essen, Essen, Germany; Robin Lemmens, Univ Hosp Leuven, Leuven, Belgium; Philippe Lyrer, Univsspital Basel, Basel, Switzerland; Carlos Molina, Val d'Hebron Hosp, Barcelona, Spain; Gilles Avenard, Hop Bichat, Paris, France; Actimis investigators

1:30 PM

Board # 2329

Intermittent Xe-Liposomes Induce Epigenetic Changes That Confirm Adaptive Cytoprotection for Post-Stroke

**Shaoling Huang** , Xing Yin, Univ of Texas Houston, Houston, TX; Manoj Pandurang Dandekar, Tao Peng, Univ of Texas Health Science Ctr, Houston, TX; Wei Guo, Zymo Reserach Corporate, Irvine, CA; Melvin E Klegerman, Univ Texas Health Sci Ctr, Houston, TX; Melanie R Moody, UT Health Science Ctr Houst, Houston, TX; Hyunggun Kim, Sungkyunkwan Univ, Suwon; Jaroslaw A Aronowski, Univ of Texax HSC Houston, Houston, TX; David McPherson, Univ of Texas Hsc at Houston, Houston, TX; Keith Booher, Zymo Reserach Corporate, Irvine, TX

1:30 PM

Board # 2330

Image-based Patient-specific Analysis Could Accurately Predict Stroke Events in Pediatric Cerebrovascular Disease

**Shaolie S Hossain** , Texas Heart Inst, Houston, TX; Zbigniew Starosolski, Texas Children's Hosp, Houston, TX; Travis Sanders, The Univ of Texas at Austin, Austin, TX; Michael Wu, Brown Univ, Providence, RI; Ming-Chen Hsu, Iowa State Univ, Ames, IA; Dianna Milewicz, Univ of Texas Health Science, Houston, TX; Ananth Annapragada, Texas Children's Hosp, Houston, TX

1:30 PM

Board # 2331

Neuroprotectin D1 Induces Protection After Brain Ischemic Injury in a Mouse Stroke Model by Blocking Mitochondria-mediated Cell Death Pathways

**Hylde Zirpoli** , Sergey A. Sosunov, Zoya V. Niatsetskaya, Korapat Mayurasakorn, Denny Joseph Manual Kollareth, Columbia Univ Medical Ctr, New York, NY; Paul C. Norris, Charles N. Serhan, Brigham and Women's Hosp and Harvard Medical Sch, Boston, MA; Vadim S. Ten, Richard J. Deckelbaum, Columbia Univ Medical Ctr, New York, NY

1:30 PM

Board # 2332

Quantitative Analysis of Flow Vortices for Predicting Middle Cerebral Aneurysm Rupture

**Kevin Sunderland** , Michigan Technological Univ, Houghton, MI; Min Wang, Texas Tech Univ, Lubbock, TX; Aditya Pandey, Joseph Gemmete, Univ of Michigan, Ann Arbor, MI; Qinghai Huang, Changhai Hosp, Second Military Medical Univ, Shanghai, China; Jingfeng Jiang, Michigan Tech Univ, Houghton, MI

1:30 PM

Poster Professor

Minjee Kim, Evanston, IL

1:30 PM

Board # 2333

Burden and Impact of Cardiovascular Events versus Cerebrovascular Events in Moyamoya Disease: A Nationwide Inpatient Perspective, 2000-2015

Rupak Desai, Atlanta VA Medical Ctr, Decatur, GA; **Upenkumar Patel** , Nassau Univ Medical Ctr, East Meadow, NY; Smit Patel, Univ of Connecticut, Farmington, CT; Yash Varma, Guthrie Robert Packer Hosp, Sayre, PA; Manan Vyas, St. Martinus Faculty of Med, Willemstad, Curaçao; Tarang Parekh, George Mason Univ, Fairfax, VA; Abhimanyu Ravalani, St. Peters Univ Hosp, New Brunswick, NJ; Samarthkumar Thakkar, Rochester General Hosp, new york, NY; Rajesh Sachdeva, Morehouse Sch of Med & Emory Sch of Med & Atlanta VA Medical Ctr, Atlanta, GA; Gautam Kumar, Emory Univ & Atlanta VA Medical Ctr, Decatur, GA

1:30 PM

Board # 2334

Hypertension, Albuminuria and Fatal Stroke Long After Acute Coronary Syndrome. The ABC Study on Acute Coronary Syndrome

**Giuseppe Berton** , Conegliano General Hosp, Conegliano, Italy; Palmieri Rosa, Rocco Cordiano, Adria General Hosp, Adria, Italy; Fiorella Cavuto, Bassano del grappa General Hosp., Bassano del grappa, Italy; Heba T Mahmoud, The ABC Heart Disease Fndn, Conegliano, Italy; Moemen M Mahmoud, Minia university hospital, Minia, Egypt; Nadir Sitta, Giuseppe Allocca, Arianna Cati, Conegliano General Hosp, Conegliano, Italy; Beatrice Segafredo, The ABC heart disease foundation., Conegliano, Italy

1:30 PM

Board # 2335

DHA Interaction With Therapeutic Hypothermia in a Neonatal Mice Stroke Model

**Denny Joseph Manual Kollareth** , Hylde Zirpoli, Richard J. Deckelbaum, Columbia Univ Medical Ctr, New York, NY; Vadim S. Ten, Columbia Univ Medical Ctr, NY, NY

1:30 PM

Board # 2336

The Reinstitution of Anticoagulation After Intracerebral Bleeding - A Meta-Analysis and Literature Review

**Salman Assad** , Marshall Univ Sch of Med, Huntington, WV; Kanaan Mansoor, Marshall Univ, Huntington, WV; Ahmed Hassaan Qavi, Brigham and Women's Hosp, Harvard Medical Sch, Boston, MA

1:30 PM

Board # 2337

Targeting Nanoparticles to Migrating Leukocytes in the Inflamed Brain

**Oscar Armando Marcos-Contreras** , Colin Greineder, Univ of Pennsylvania, Philadelphia, PA; Viviana Zuluaga-Ramirez, Temple Univ, Philadelphia, PA; Patrick M Glassman, Landis Walsh, Raisa Yu Kiseleva, Elizabeth D Hood, Carlos Villa, Jacob W Myerson, Jacob S Brenner, Univ of Pennsylvania, Philadelphia, PA; Yuri Persidsky, Temple Univ, Philadelphia, PA; Vladimir R Muzykantov, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 2338

ET-B Receptors Agonist, Sovateltide (IRL-1620), Promotes Mitochondrial Biogenesis and Neural Regeneration After Cerebral Ischemic Stroke

Amaresh Ranjan, Seema Briyal, Midwestern Univ, Downers Grove, IL; **Anil Gulati** , Pharmazz, Inc and Midwestern Univ, Downers Grove, IL

# Abstract Poster Session

## ST.APS.02 - Stroke Epidemiology and Outcomes Research

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2319

Brain Injury and Neurologic Outcome in Patients Undergoing Extracorporeal Cardiopulmonary Resuscitation: A Systematic Review and Meta-Analysis

**Sung-Min Cho** , Johns Hopkins Univ Sch of Med, Baltimore, MD; Cory J Rice, The Cleveland Clinic Fndn, Cleveland, OH; Romergryko Geocadin, Johns Hopkins Univ Sch of Med, Baltimore, MD; Ibrahim Migdady, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 2320

Outcomes Following Left Atrial Appendage Occlusion in Patients With Cerebral Amyloid Angiopathy and Prior Intracerebral Hemorrhage

**Majd A El-Harasis** , Mayo Clinic, Rochester, MN; Shiva P Ponamgi, Mayo Clinic, Austin, MN; Robert Ward, Stephen English, Christopher V Desimone, Jonathan Graff-Radford, Mayo Clinic, Rochester, MN; Alejandro A Rabinstein, Mayo Clinic Neurology, Rochester, MN; Thomas Michael Munger, Mayo Clinic, Rochester, MN; Samuel Asirvatham, Mayo Fndn, Rochester, MN; David R Holmes, Mayo Clinic, Rochester, MN

1:30 PM

Board # 2321

Trends in Prevalence of Strokes in Adults With Sickle Cell Disease- An Analysis of National Inpatient Sample Database

**Janani Baskaran** , Swathi Somisetty, ammara khan, Creighton Univ, Omaha, NE; Mahesh Anantha Narayanan, Univ of Minnesota, Minneapolis, MN; Sarah Aurit, Praveen Hariharan, Maryam Gbadamosi-Akindele, Creighton Univ, Omaha, NE

1:30 PM

Board # 2322

Predicting Initial and Subsequent 3 Year Follow-Up Cost After Hospitalization for First Acute Ischemic Stroke

Mohammed Yousufuddin, Mayo Clinic Health System, Austin, MN; James Moriarty, Mayo Clinic, Rochester, MN; **Jessica Peters** , Taylor Doyle, Mayo Clinic Health System, Austin, MN; Bijan Borah, Mohammad H Murad, Mayo Clinic, Rochester, MN

1:30 PM

Board # 2323

Ethnic Trends of Acute Ischemic Stroke Incidence and Risk Factors in a Multiethnic Population in Southeast Asia: A 12-year Study Using a Nationwide Stroke Registry

**Dawn Cheah** , Natl Univ of Singapore, Singapore, Singapore; Benjamin Y Tan, Natl Univ Hosp, Singapore, Singapore; Pin Pin Pek, Singapore General Hosp, Singapore, Singapore; Zheng Huili, Health Promotion Board, Singapore, Singapore, Singapore; Deidre A De Silva, Natl Neuroscience Inst, Singapore, Singapore; Aftab Ahmad, NUHS, Singapore; Bernard P Chan, Natl Univ Hosp, Singapore; Chang Hui Meng, Natl Neuroscience Inst, Singapore, Singapore; Kong Keng, Tan Tock Seng Hosp, Singapore, Singapore; Sherry Young, Changi General Hosp, Singapore; Kok Foo Tang, Mount Elizabeth Hosp, Singapore, Singapore; Leonard L Yeo, Natl Univ Hosp, Singapore, Singapore; Narayanaswamy Venketasubramanian, Raffles Hosp, Singapore, Singapore; Andrew Ho, Marcus Eng Hock Ong, Singapore General Hosp, Singapore, Singapore

1:30 PM

Board # 2324

Left Atrial Appendage Closure In Patients With End-stage Chronic Kidney Disease: Experience With 156 Consecutive Cases At A Single Center

Swaiman Singh, Newark Beth Israel Medical Ctr, Jackson, NJ; **Alexis K Okoh** , RWJ Barnabas Health NBIMC, Newark, NJ; harsh mehta, Saint Barnabas Medical Ctr, Livingston, NJ; Mayal Sandhu, RWJ Barnabas Health NBIMC, Newark, NJ; Vijay Singh, RWJ Barnabas Health., Newark, NJ; Mann Rajmeet, Norton Community Hosp, Norton, NJ; David Dobesh, RWJ Barnabas Health NBIMC, New York, NY; Marc Cohen, Sergio Waxman, Newark Beth Israel Medical Ctr, Newark, NJ

1:30 PM

Board # 2325

The Association Between Low-Density Lipoprotein Cholesterol and the Risk of Hemorrhagic Stroke

**Samip Sheth** , Paul Lee, Edward Gomes, Marjorie Risman, Daniel J Rader, Douglas Jacoby, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 2326

Increased Risk of Stroke in Patients With High Chads2 Score Without History of Atrial Fibrillation

**Abel E. Moreyra** , Davit Sargsyan, Javier Cabrera, William J. Kostis, Rutgers Robert Wood Johnson Medical Sch, New Brunswick, NJ; for the MIDAS Study Group

1:30 PM

Board # 2327

Increasing Use of Endovascular Thrombectomy Among California Stroke Patients After the 2015 Publication of Benefit

**Kori S Zachrison** , Massachusetts General Hosp, Boston, MA; Lee H Schwamm, MGH, Boston, MA; Sijia Li, Janice A Espinola, Carlos A Camargo Jr, Massachusetts General Hosp, Boston, MA; Renee Y Hsia, Univ of California San Francisco, San Francisco, CA

# Abstract Poster Session

## IN.APS.01 - Therapy (Antiplatelets, Antithrombotics and Anti-Lipid Agents) Around ACS and PCI

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Stephen J Voyce, S Abingtn Twp, PA

1:30 PM

Board # 4210

Beneficial Effects of Proprotein Convertase Subtilisin/kexin Type 9 Inhibitor in Patients With Acute Myocardial Infarction

Hiroyasu Uzui, Tomohiro Shimizu, Ryouhei Nomura, **Hirano Koudai** , Ootake Mika, Univ of Fukui, Fukui, Japan; Moe Mukai, Univ of Fukui Hosp, Eiheizi-cho, Japan; Eri Ishikawa, Akira Matsui, Daisetsu Aoyama, Univ of Fukui, Fukui, Japan; Yuichiro Shiomi, Univ of Fukui, Matuoka Eiheiji, Japan; Naoto Tama, Hiroyuki Ikeda, Yoshitomo Fukuoka, Kanae Hasegawa, Kentaro Ishida, Kenichi Kaseno, Shinsuke Miyazaki, Hiroshi Tada, Univ of Fukui, Fukui, Japan

1:30 PM

Board # 4211

Current Status of Long-Term Dual-Antiplatelet Therapy After Percutaneous Coronary Intervention in Japan: Findings From the National Database

**Koshiro Kanaoka** , Nara Medical Univ, Kashihara, Japan; Satoshi Terasaki, Nara Medical Univ, Nara-Ken Kashihara-ahi, Japan; Yuichi Nishioka, Shinichiro Kubo, Tomoya Myojin, Tsunenari Soeda, Tatsuya Noda, Makoto Watanabe, Rika Kawakami, Tomoaki Imamura, Yoshihiko Saito, Nara Medical Univ, Kashihara, Japan

1:30 PM

Board # 4212

The Importance of Coronary Revascularization and Guideline-Directed Medical Therapy (GDMT) in Elderly With Non-ST Elevation Acute Coronary Syndrome (NSTEACS)

**Jonathan X Fang** , Frankie CC Tam, Simon CC Lam, Queen Mary Hosp, Hong Kong, Hong Kong, Hong Kong; Hung Fat Tse, Univ of Hong Kong, Hong Kong

1:30 PM

Board # 4213

Double Therapy versus Triple Therapy for Patients With Atrial Fibrillation and Percutaneous Coronary Intervention or Acute Coronary Syndrome: A Meta-analysis

Venkatesh Ravi, John H Stroger Jr Hosp of Cook County, Chicago, IL; **Priyanjali Pulipati** , Univ of Iowa - Carver Coll of Med, Iowa City, IA; Aviral Vij, John H Stroger Jr Hosp, Chicago, IL; Vamsi Kodumuri, John H Stroger Jr Hosp of Cook County, Chicago, IL

1:30 PM

Board # 4214

Statins Were Effective to Lower Long-Term Cardiovascular Mortalities in Patients Treated by Chronic Hemodialysis Underwent Percutaneous Coronary Intervention

**Takehiro Funamizu** , Juntendo Univ, Tokyo, Japan; Hiroshi Iwata, Juntendo Univ, Tokyo, MA, Japan; Yuichi Chikata, Juntendo Univ, Bunkyo, Japan; Shinichiro Doi, Juntendo Univ Sch of Medic, Tokyo, Japan; Hirohisa Endo, Juntendo Univ, Tokyo, Japan; Hideki Wada, Juntendo Univ Shizuoka Hospit, Izunokuni Shizuoka, Japan; Ryo Naito, Juntendo Univ, Tokyo, Japan; Hirokazu Konishi, Juntendo Univ, Shizuoka, Japan; Manabu Ogita, Juntendo Univ Shizuoka Hosp, Izunokuni, Japan; Yoshiteru Kato, Iwao Okai, Tomotaka Dohi, Takatoshi Kasai, Kikuo Isoda, Shinya Okazaki, Katsumi Miyauchi, Juntendo Univ, Tokyo, Japan

1:30 PM

Board # 4215

Network Meta Analysis of Regimens in Patients With Atrial Fibrilation Undergoing Percutanoues Coronary Intervention

**Alexander Ivanov** , New York Methodist, Brooklyn, NY; Bharat Ravishankar, New York-Presbyterian Brooklyn Methodist Hosp, Brooklyn, NY

1:30 PM

Board # 4216

Dual Antiplatelet Therapy for Three Months Followed by Monotherapy is Non-inferior to One Year Dual Antiplatelet Therapy in Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention- A Systematic Review and Meta-Analysis

**Muhammad Fazeel Anwar** , Creighton Univ Medical Ctr, Omaha, NE; Behram Ahmed Khan, Sims Lahore, Lahore, Pakistan; Syeda Fatima Hassan, Univ of Lahore, Lahore, Pakistan; Sarwat Nasreen, Maimonides Medical Ctr, Brooklyn, NY; Saad Ullah Malik, Rawalpindi Medical Coll, Tucson, AZ; Hafiz Muhammad Fazeel, Sims Lahore, Lahore, Pakistan; Asim Tameez Ud Din, Rawalpindi Medical Coll, Rawalpindi, Pakistan; Jacqueline Chung, Mohsin Mirza, Creighton Univ Medical Ctr, Omaha, NE

1:30 PM

Board # 4217

Platelet Inhibition of Ticagrelor versus Clopidogrel in Diabetic Patients After Elective Percutaneous Coronary Intervention for Stable Coronary Artery Disease

**Zhenyu Liu** , Ran Tian, PUMC Hosp, Beijing, China; Yang Wang, Natl Ctr for Cardiovascular Diseases & Fu-Wai Hosp, Beijing, China; Qian Chen, Jingyi Li, Lihong Xu, Shuyang Zhang, PUMC Hosp, Beijing, China

1:30 PM

Board # 4218

Prolonged Enoxaparin Infusion in Patients Undergoing Primary Percutaneous Coronary Intervention Compared to Standard-of-care: A Single-centre Clinical Trial

**Wael Sumaya** , Univ of Sheffield, Sheffield, United Kingdom; William Parker, The Univ of Sheffield, Sheffield; Heather Marie Judge, Clinical Sciences Ctr,, Sheffield; Ian R Hall, Sheffield Teaching Hosp NHS Fndn Trust, Sheffield, United Kingdom; Rachel Claire Orme, Univ of Sheffield, Sheffield, United Kingdom; Zulfiquar Adam, James D Richardson, Sheffield Teaching Hosp NHS Fndn Trust, Sheffield, United Kingdom; Alex M Rothman, Univ of Sheffield, Sheffield, United Kingdom; Kenneth P Morgan, Sheffield Teaching Hosp, Sheffield, United Kingdom; Julian P Gunn, Univ of Sheffield, Sheffield, United Kingdom; Robert F Storey, Univ of Sheffield Medical Sch, Sheffield, Ukraine

1:30 PM

Board # 4219

Impact of Emergency Premedication Regimen in Patients With Contrast Allergy Before Undergoing Elective and Nonelective Percutaneous Coronary Intervention

**Kunal Jha** , Andrea Berger, James C Blankenship, Geisinger Medical Ctr, Danville, PA

# Abstract Poster Session

## VA.APS.02 - Trailblazing at the Crossroads of Critical Limb Ischemia and Peripheral Revascularization

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4304

Initial Tissue Doppler E/e′ Ratio is a Powerful Predictor of 5-Year Mortality in Peripheral Arterial Disease Patients Undergoing Percutaneous Transluminal Angioplasty

**Kyung-hee Kim** , Sejong General Hosp, Incheon, Korea, Republic of; Seung Woon Rha, Byoung Geol Choi, Korea Univ, Guro Hosp, Seoul, Korea, Republic of; Yoonjee Park, Korea Univ. Guro Hosp, Seoul; Woohyeun Kim, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Dong Oh Kang, Korea Univ Guro Hosp, Seoul; Jin Oh Na, Korea Univ, Guro Hosp, Seoul, Korea, Republic of; Cheol Ung Choi, Korea Univerity, Guro Hosp, Seoul, Korea, Republic of; Chang Gyu Park, Korea university, guro hospital, Seoul, Korea, Republic of

1:30 PM

Board # 4305

Risk Stratification for Critical Limb Ischemia and Amputation in Patients With Atherosclerosis: Insights From the TRA2P-TIMI 50 Trial

**Marc P Bonaca** , Univ of Colorado, Aurora, CO; Arman Qamar, Brigham and Women's Hosp, Boston, MA; Mark A Creager, Dartmouth-Hitchcock Medical Ctr, Lebanon, NH; Jeong-Gun Park, Benjamin M Scirica, David A Morrow, Brigham and Women's Hosp, Boston, MA; Marc S Sabatine, TIMI Study Group, Boston, MA

1:30 PM

Board # 4306

Long-term Cardiovascular and Limb Outcomes and Associations With Major Adverse Limb Events After Peripheral Revascularization

**Connie N Hess** , Univ of Colorado Sch of Med, Aurora, CO; Tracy Y Wang, DCRI, Durham, NC; Julia Weleski Fu, Jacob Gundrum, Nancy Allen LaPointe, Premier, Inc, Charlotte, NC; Robert K Rogers, Univ of Colorado Denver, Aurora, CO; William R. Hiatt, Univ of Colorado Sch of Med, Aurora, CO

1:30 PM

Board # 4307

Progressive Thrombocytopenia in Critical Limb Ischemia as a Novel Cardiovascular Rsk

**Kaoru Tateno** , Yukiko Toyoda, Masanori Hirose, Naomichi Kondo, Masato Kanda, Yoshio Kobayashi, Div of Cardiovascular Med Chiba Univ, Chiba, Japan

1:30 PM

Board # 4308

Clinical Predictors of Readmission to the Hospital at 1-Year Following Elective Vascular Surgery

**Asrar Ahmed Khan** , Univ of Minnesota, Minneapolis, MN; Selma Carlson, VA Medical Ctr, Minneapolis, MN; Mackenzie Mbai, Univ of Minnesota, Plymouth, MN; Debra Johnson, Univ of Minnesota, Minneapolis, MN; Steve Santilli, Derrick Green, VA Medical Ctr Univ MN, Minneapolis, MN; Santiago Garcia, Minneapolis Heart Inst, Edina, MN; Rosemary Frances KELLY, Amy Gravely, Univ of Minnesota, Minneapolis, MN; Selcuk Adabag, Minneapolis VA Medical Ctr, Minneapolis, MN; Edward O McFalls, VA Medical Ctr Univ MN, Minneapolis, MN

1:30 PM

Board # 4309

Our Experience of Treatment in Patients With Peripheral Arterial Diseases and Critical Limb Ischemia

**Nasraddin Abushov** , Elmar Zakirjayev, Scientific Ctr of Surgery named after M.A. Topchubashov, Baku, Azerbaijan; Mahammad Karimov, Azerbaijan Medical Univ, Baku, Azerbaijan; Gamar Zeynalova, Sadiq Ahmadov, Leyla Mammadova, Scientific Ctr of Surgery named after M.A. Topchubashov, Baku, Azerbaijan

1:30 PM

Board # 4310

Coronary Artery Disease, Epicardial Adipose Tissue and Perioperative Risk in Patients Undergoing Abdominal Aortic Aneurysm Repair Surgery

Caio Vinicius F Rodrigues, INCOR (Heart Inst), Sao Paulo, Brazil; Gustavo Teles, HIAE, Sao Paulo, Brazil; Mark Wanderley, Clinics Hosp, Sao Paulo, Brazil; **Francisco M Malta Cardozo** , Pai C Yu, Danielle Gualandro, INCOR (Heart Inst), Sao Paulo, Brazil; Ivan B Casella, Erasmo Silva, Clinics Hosp, Sao Paulo, Brazil; Bruno Caramelli, Univ of Sao Paulo, Sao Paulo, Brazil; Daniela Calderaro, INCOR (Heart Inst), Sao Paulo, Brazil

1:30 PM

Board # 4311

Intravenous Administration of Notch Signaling Modified Mesenchymal Stem Cell Improves Tissue Perfusion by the Induction of Arteriogenesis in a Rat Hind Limb Ischemia Model

**Shusaku Maeda** , Shigeru Miyagawa, Takashi Shibuya, Osaka Univ, Suita, Japan; Takuji Kawamura, Osaka Univ, Osaka, Japan; Kenichi Watanabe, Akima Harada, Osaka Univ, Suita, Japan; Dai Chida, Sanbio, Tokyo, Japan; Takayoshi Ueno, Osaka Univ Graduate Sch of Med, Suita, Japan; Koichi Toda, Osaka Univ, Suita, Japan; Yoshiki Sawa, Osaka Univ, Osaka, Japan

1:30 PM

Board # 4312

Rosuvastatin Slows Progression of Carotid Intima-media Thickness in Low-risk Chinese Individuals With Subclinical Atherosclerosis (the Meteor-china Study)

Yongjun Wang, Beijing Tian Tan Hosp, Capital Medical Univ, Beijing, China; **Bilian Zhao** , Cardiovascular Renal Metabolism Clinical Science, R&D China, AstraZeneca, Shanghai, China; Björn W Karlson, Dept of Molecular and Clinical Med, Inst of Med, Sahlgrenska Acad, Univ of Gothenburg, Gothenburg, Sweden and AstraZeneca R&D Gothenburg,, Mölndal, Sweden; Di Wei, R&D China, AstraZeneca, Shanghai, China; Michael L Bots, Julius Ctr for Health Sciences and Primary Care, Univ Medical Ctr, Utrecht Univ, Utrecht, Netherlands; Yundai Chen, Dept of Cardiology, China PLA General Hosp, Beijing, China

1:30 PM

Board # 4313

A Randomized Trial of Low-Dose Aspirin to Reduce Vascular Endothelial Inflammation in Psoriasis

**Michael S Garshick** , Michael Tawil, New York Univ Medical Ctr, New York, NY; Tessa Barrett, NYU Sch of Med, New York, NY; Angela Lee, NYU Langone Health, New York City, NY; Andrea Neimann, Jose Scher, New York Univ Medical Ctr, New York, NY; Stuart D Katz, New York Univ Sch Med, New York, NY; Sanja Jelic, Columbia Univ, New York, NY; Edward A Fisher, NYU Langone Medical Ctr, New York, NY; James Krueger, Rockefeller Univ, New York, NY; Jeffrey S Berger, NEW YORK UNIVERSITY SCHOOL MEDICINE, New York, NY

# Abstract Poster Session

## CH.APS.01 - Translational Research in Congenital Heart Disease

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4032

Assessment of Gadolinium Deposition in the Brain Tissue of Pediatric and Adult Congenital Heart Disease Patients After Cardiac MRI

**Neil C Zaki** , David A Parra, Quinn Wells, Joshua Chew, Kristen George-Durrett, Sumit Pruthi, Jonathan H Soslow, Vanderbilt Univ Medical Ctr, Nashville, TN

1:30 PM

Board # 4033

The Administration of Autologous Skeletal Myoblast Sheet Prevents Deterioration of a Pressure-overloaded Right Heart in a Porcine Model

**Kanta Araki** , Osaka university, Suita, Japan; Shigeru Miyagawa, Osaka Univ, Suita, Japan; Takuji Kawamura, Osaka Univ, Osaka, Japan; Ryo Ishii, Osaka Univ, Suita, Japan; Akima Harada, Osaka Univ, Osaka, Japan; Takayoshi Ueno, Osaka Univ Graduate Sch of Med, Suita, Japan; Toda Koichi, Osaka Univ, Suita, Japan; Toru Kuratani, Osaka Univ / CV Surgery, Osaka, Japan; Yoshiki Sawa, Osaka Univ Graduate Sch of, Osaka, Japan

1:30 PM

Board # 4034

Tricuspid Valve (TV) Adapt to Chronic Right Ventricular (RV) Pressure and Volume Load Stress by Rapid Leaflet Expansion: A Three-dimensional Echocardiography (3DE) Study in a Novel Piglet Model

**Lily Q. Lin** , Univ of Alberta, Stollery Children's Hosp, Edmonton, AB, Canada; Sanaz Hatami, Richard Thompson, Consolato Sergi, James Y Coe, Timothy M Colen, Univ of Alberta, Edmonton, AB, Canada; Elena S Di Martino, Walter Herzog, Ziad Abu Sara, Univ of Calgary, Calgary, AB, Canada; Darren H Freed, Nee Scze Khoo, Univ of Alberta, Edmonton, AB, Canada

1:30 PM

Board # 4035

**The Mutation R94C In** TNNT2 **-encoded Troponin T Predisposes to Restrictive Cardiomyopathy and Pediatric Sudden Death Through Impaired Thin Filament Relaxation Resulting in Myocardial Diastolic Dysfunction**

**Jordan E Ezekian** , Duke Univ Medical Ctr, Durham, NC; Sarah R Clippinger, Washington Univerisity in St. Louis, St. Louis, MO; Jackie Garcia, Washington Univ in St. Louis, St. Louis, MO; Susan W Denfield, Baylor Coll Med, Houston, TX; Aamir Jeewa, The Hosp for Sick Children, Toronto, ON, Canada; William Dreyer, Texas Children's Hosp, Houston, TX; Wenxin Zou, Baylor Coll of Med, Houston, TX; Yuxin Fan, Baylor Coll Med, Houston, TX; Hugh D Allen, Texas Children's Hosp, Houston, TX; Jeffrey Kim, Baylor Coll of Med, Houston, TX; Michael Greenberg, Washington Univ, Saint Louis, MO; Andrew P Landstrom, Duke Univ Sch of Med, Durham, NC

1:30 PM

Board # 4036

Comparative Study of Gene Expression Profiling, Global Left Ventricular Relaxation Index and Cardiac Hemodynamics After Pediatric Heart Transplantation

**Bibhuti B Das** , Robert Winchester, Joe DiMaggio Children's Hosp, Hollywood, FL; Jianli Niu, Memorial Healthcare System, Hollywood, FL

1:30 PM

Board # 4037

Reactive Oxygen Species Accumulation and Mitochondrial Dysfunction in Peripheral Blood Mononuclear Cells Are Associated With Heart Failure in Patients With Single Ventricle Congenital Heart Disease

**Anastacia M Garcia** , Genevieve C Sparagna, Elisabeth K Phillips, Carissa A Miyano, Karin Nunley, Kathryn C Chatfield, Brian L Stauffer, Carmen Sucharov, Univ of Colorado Denver, Aurora, CO; Shelley D Miyamoto, Childrens Hosp Colorado, Aurora, CO

1:30 PM

Board # 4038

Remote Ischemic Preconditioning Does Not Prevent Placental Dysfunction Induced by Extrcorporeal Circulation in Fetal Lambs

**Renato S Assad** , Heart Inst Univ of Sao Paulo, Sao Paulo, SP, Brazil; Marcelo G. Guedes, Vera D. Aiello, Petronio G. Thomaz, Heart Inst Univ of Sao Paulo, Sao Paulo, Brazil; Fernando L. Zanoni, Sch of Med Univ of Sao Paulo, Sao Paulo, Brazil; Ana Cristina A. Arashiro, Heart Inst Univ Sao Paulo, Sao Paulo, Brazil; Ana Paula N. da Silva, Heart Inst Univ of Sao Paulo, Sao Paulo, Brazil; Raphael S. Coutinho e Silva, Sch of Med Univ of Sao Paulo, Sao Paulo, Brazil; Ana Cristina B. Faloppa, Sch of Med Univ of Sao Paulo, Sao Paulo, SP, Brazil; Marcelo V. Pinto, Heart Inst Univ Sao Paulo, Sao Paulo, Brazil; Marcelo B Jatene, Luiz Felipe P. Moreira, Heart Inst Univ of Sao Paulo, Sao Paulo, Brazil

1:30 PM

Board # 4039

Bisphenol-a Analogues May Be Safer Alternatives For Plastic Medical Products

Rafael Jaimes, Damon McCullough, Luther M Swift, Marissa Reilly, Morgan Burke, Children's Natl Medical Ctr, Washington, DC; Jiansong Sheng, CiPA labs, Gaithersburg, MD; Javier Saiz, Ci2B- Univ Politècnica de València, Valencia, Spain; **Nikki G Posnack** , Children's Natl Medical Ctr, Washington, DC

1:30 PM

Board # 4040

Serum Metabolic Fingerprint of Acute Kidney Injury Following Infant Cardiac Surgery With Cardiopulmonary Bypass

**Jesse Davidson** , Univ of Colorado Denver/Children's Hosp Colorado, Aurora, CO; Benjamin Frank, Univ of Colorado Denver/Children's Hosp Colorado, Denver, CO; Tracy Urban, Children's Hosp Colorado, Denver, CO; Ludmila Khailova, Univ of Colorado Denver/Children's Hosp Colorado, Denver, CO; Jelena Klawitter, Univ of Colorado AMC, Aurora, CO

1:30 PM

Board # 4041

Association Between Caffeine and Post-Cardiopulmonary Bypass Acute Kidney Injury in Infants

**Elizabeth J. Thompson** , Karan Kumar, Duke Univ Medical Ctr, Durham, NC; Elizabeth Ciociola, Duke Clinical Res Inst, Durham, NC; Laura Sullivan, Joseph W Turek, Duke Univ Medical Ctr, Durham, NC; Kevin D Hill, Duke Clinical Res Inst, Durham, NC; Christoph P Hornik, Duke Univ Medical Ctr, Durham, NC

1:30 PM

Poster Professor

Christopher Spurney, Washington, DC

1:30 PM

Board # 4042

Predictors of Left Ventricular Size and Function Normalization in Pediatric Dilated Cardiomyopathy Patients

**Jenna Ashkanase** , Aamir Jeewa, Sunghoon Minn, Katelyn Arathoon, Seema Mital, Anne I Dipchand, Emilie Jean-St-Michel, Hosp for Sick Children, Toronto, ON, Canada

1:30 PM

Board # 4043

Copeptin: A Novel Biomarker in Pediatric Heart Failure Due to Cardiomyopathies

**Karan B Karki** , Jeffrey A Towbin, Ranjit Raju Philip, Camden Harrell, Sachin Tadphale, Samir Shah, Le Bonheur Children's Hosp, Memphis, TN; Arun Saini, Baylor Coll of Med, Houston, TX

1:30 PM

Board # 4044

Xenotransplantation Acceptance Among Parents and Healthcare Providers Involved in the Care of Children With Congenital Heart Disease

**Luz A Padilla** , Univ of Alabama at Birmingham, Birmingham, AL; Wayne Paris, Abilene Christian Univ, Abilene, TX; Rongbing Xie, Leslie Rhodes, Zviadi Aburjania, Robert J Dabal, David Mauchley, David KC Cooper, David Cleveland, Waldemar F Carlo, Univ of Alabama at Birmingham, Birmingham, AL

# Abstract Poster Session

## IN.APS.02 - Understanding the Vascular Complications of PCI, Shock and Cardiac Arrest

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4220

Predictors of Outcomes in Men and Women Undergoing Percutaneous Coronary Intervention for Unprotected Left Main Stenosis

**Anastasios Roumeliotis** , Davide Cao, Roxana Mehran, George Dangas, Rishi Chandiramani, Moritz Blum, Ridhima Goel, Bimmer E Claessen, Samantha Sartori, Melissa Aquino, Icahn Sch of Med at Mount Sinai, New York, NY; Asaad Akbar khan, Joseph Sweeny, Jason C Kovacic, Javed Suleman, Hasan Choudhury, Srinivas Kesanakurthy, Vishal Kapur, Nitin Barman, Prakash Krishnan, Usman Baber, Samin K. Sharma, Annapoorna Kini, Mount Sinai Hosp, New York, NY

1:30 PM

Board # 4221

Initial Serum Lactate Predicts Mortality After Cardiac Catheterization Following Cardiac Arrest

**Chen-yu C Guo** , Russell Rosenberg, Kraftin Schreyer, Riyaz Bashir, Brian O'Murchu, Lewis Katz Sch of Med at Temple Univ, Philadelphia, PA; Vikas Aggarwal, Univ of Michigan, Ann Arbor, MI; Debbie Weiss, Michael DeAngelis, Daniel Edmundowicz, Brian O'Neill, Lewis Katz Sch of Med at Temple Univ, Philadelphia, PA

1:30 PM

Board # 4222

Peptide CD47 Functionalization of Metal Surfaces Prevents Inflammatory Cell Attachment, Activation and Promotes Anti-Inflammatory Phenotype in Macrophages

**Vaishali Inamdar** , Emmett Fitzpatrick, Ivan Alferiev, Children's Hosp of Philadelphia, Philadelphia, PA; Chandrasekaran Nagasami, Univ of Pennsylvania, Philadelphia, PA; Robert Levy, Children's Hosp of Philadelphia, Philadelphia, PA; Ilia Fishbein, The Childrens Hosp of Philadelphia, Philadelphia, PA; Stanley Joseph Stachelek, Childrens Hosp of Philadelphia, Philadelphia, PA

1:30 PM

Board # 4224

Complete Revascularization is Associated With Less In-hospital Mortality in Cardiogenic Arrest Survivors With Multi-vessel Coronary Artery Disease

**Chih-Wei Sung** , Natl Taiwan Univ Hosp Hsin-Chu Branch, Hsinchu, Taiwan; Chien-Hua Huang, Wen-Jone Chen, Wei-tien Chang, Natl Taiwan Univ Hosp, Taipei, Taiwan; Jia-How Chang, Natl Taiwan Univ Hosp Hsin-Chu Branch, Hsinchu, Taiwan; Min-Shan Tsai, Natl Taiwan Univ Hosp, Taipei, Taiwan

1:30 PM

Board # 4225

Racial And Gender Disparities In Shift To Outpatient Revascularization Among Medicare Fee-for-service Beneficiaries

Samuel Savitz, Div of Res, Oakland, CA; **Kristine M Falk** , Univ of North Carolina, Chapel Hill, NC; Sally C Stearns, UNC-Chapel Hill, Chapel Hill, NC; Jason Fines, Lexie Grove, Joseph Rossi, Univ of North Carolina, Chapel Hill, NC

1:30 PM

Board # 4226

Early and Late Vascular Response Afterbiodegradable-Polymer Sirolimus-Eluting Stent Implantation in St Elevation Myocardial Infarction〜Sub-Analysis of Mechanism-Ultimaster Trial〜

**Takumi Kimura** , Iwate Medical Univ, Morioka, Iwate, Japan; Tomonori Itoh, Masaru Ishida, Iwate Medical Univ, Morioka, Japan; Hiromasa Otake, Kobe Univ, Kobe, Hyougo, Japan; Yoshihiro Morino, Iwate Medical Univ, Marioka, Japan

1:30 PM

Board # 4227

Successful Modeling of Long Term Death and Mace in Esrd Patients Receiving Des: C-reactive Peptide, Peripheral Vascular Disease, and Other Key Factors

Stephen G Ellis, Chetan Huded, Cleveland Clinic Fndn, Cleveland, OH; **Aaron Dunn** , Cleveland Clinic Lerner Coll of Med, Cleveland, OH; Russell Raymond, A Michael Michael Lincoff, Christopher Bajzer, Samir R Kapadia, Cleveland Clinic Fndn, Cleveland, OH

1:30 PM

Poster Professor

Rajesh V Swaminathan, Durham, NC

1:30 PM

Board # 4228

Vascular Complications in Patients With STEMI and Cardiogenic Shock With Percutaneous Mechanical Circulatory Support Devices: Prevalence and Clinical Outcomes From a Large Nationwide Database

**Mohit Pahuja** , Wayne State Univ, Detroit, MI; Omar Chehab, Wayne State Univ-DMC, Detroit, MI; Ahmed Yassin, Detroit Medical Ctr/Wayne State Univ, Detroit, MI; Sagar Ranka, John H Stroger Hosp of Cook Cou, Chicago, IL; Tushar Mishra, Detroit Medical Ctr/Wayne State Univ, Detroit, MI; Hossam Abubakar, Aman Handa, Wayne State Univ, Detroit, MI; Khosla Tanvir, N/A, Detroit, MI; Tomo Ando, Detroit Medical Ctr, Detroit, MI; Navin K Kapur, Tufts Medical Ctr, Hanover, MA

1:30 PM

Board # 4229

**Effect of Natural Vascular Scaffolding (NVS) Treatment on Human Popliteal Arteries** in vitro

**Ejaz Ansari** , REPROCELL Europe Ltd, Glasgow, United Kingdom; Blake Anderson, Katalin Kauser, Alucent Biomedical Inc., Salt Lake City, UT

1:30 PM

Board # 4230

30-Day Readmission in Patients Undergoing Transcatheter Aortic Valve Replacement With Atrial Fibrillation: A Nationwide Readmission Database Analysis

**Adrija Hajra** , Jacobi Medical Ctr, New York, NY; Dhrubajyoti Bandyopadhyay, Mount Sinai St Luke's Roosevelt, New York, NY; Neel Patel, Interfaith Medical Ctr, New York, NY; Sandipan Chakraborty, Interfaith Medical Ctr, New York, NY, Brooklyn, NY; Birendra Amgai, Interfaith Medical Ctr, Brooklyn, NY; Raktim Ghosh, MetroHealth Medical Ctr, Cleveland, OH; Soniya Koirala, Tribhuvan Univ Teaching Hosp, Kathmandu, Nepal; Eyal Herzog, Mount Sinai St Luke's, New York, NY

1:30 PM

Board # 4231

Predictors of Early Restenosis After Drug Coated Balloon Treatment for Femoropopliteal Lesions Assessed by Intravascular Ultrasound

**Shota Okuno** , Osamu Iida, Mitsutoshi Asai, Masaharu Masuda, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takashi Kanda, Takuya Tsujimura, Yasuhiro Matsuda, Yosuke Hata, Yuki Sato, Hiroyuki Uematsu, Shodai Kawanami, Hiroki Sugae, Sho Nakao, Toshiaki Mano, Kansai Rosai Hosp, Amagasaki, Japan

1:30 PM

Board # 4232

Lymphocyte-to-monocyte Ratio is an Independent Predictor of 90-day Mortality After Endovascular Therapy in the Patients With Critical Limb Ischemia

**Kohei Ukita** , Osaka Rosai Hosp, Sakai, Japan

# Abstract Poster Session

## EA.APS.03 - Ventricular Arrhythmias Risks and Substrates

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2016

The Effect of Tobacco Cigarettes and Electronic Cigarettes on Ventricular Repolarization: Implications for Sudden Death Risk

Michelle Ip, Evan Diamantakos, Kacey P Haptonstall, Yasmine Choroomi, Roya Moheimani, Kevin Nguyen, Elizabeth Tran, Jeffrey Gornbein, **Holly R Middlekauff** , UCLA Medical Ctr, Los Angeles, CA

1:30 PM

Board # 2017

Methadone-Induced QT Interval Prolongation in Patients Undergoing Maintenance Therapy in a Narcotic Treatment Center: Incidence, Risk Factors, and Association With Stereospecific Serum Methadone and Metabolite Concentrations

Erika Titus-Lay, California Northstate Univ, Elk Grove, CA; Heather A Jaynes, Elena Tomaselli-Muensterman, Purdue Univ, Indianapolis, IN; Todd Walroth, Eskenazi Health, Indianapolis, IN; Carol Ott, Purdue Univ, Indianapolis, IN; Gabriela Williams, Paul Moe, Eskenazi Health, Indianapolis, IN; **James E Tisdale** , Purdue Univ, Indianapolis, IN

1:30 PM

Board # 2018

Exploring Novel Risk Factors in Hypertrophic Cardiomyopathy Sudden Cardiac Death Risk Stratification

**Kristin Boulier** , David Hsu, Matthew T Wheeler, Stanford Univ, Stanford, CA

1:30 PM

Board # 2019

Routine Twelve-lead Electrocardiogram Measurements Offer a Simplified Means to Differentiate Wide Complex Tachycardias

**Anthony Kashou** , Christopher Desimone, Mayo Clinic, Rochester, MN; Haarini Sridhar, Stanford Univ, Stanford, CA; David Hodge, Mayo Clinic, Jacksonville, FL; Siva Mulpuru, Grace Lin, Suraj Kapa, Mayo Clinic, Rochester, MN; Samuel Asirvatham, Mayo Fndn, Rochester, MN; Peter Noseworthy, Abhishek Deshmukh, Adam May, Mayo Clinic, Rochester, MN

1:30 PM

Board # 2020

Rapid but Short Duration Ventricular Tachycardia Predicts Actionable Events

**Sukardi Suba** , UCSF Sch of Nursing, San Francisco, CA; Cass Sandoval, UCSF Medical Ctr, San Francisco, CA; Jessica Zegre-Hemsey, UNC Chapel Hill, Chapel Hill, NC; Xiao Hu, Michele M Pelter, UCSF, San Francisco, CA

1:30 PM

Board # 2021

Elevated Stressful Life Events Precede Unexplained Cardiac Arrest

**Ming Chang Liu** , Matthew Tester, Sonia Franciosi, BC Children's Hosp, Vancouver, BC, Canada; Andrew Krahn, Univ of British Columbia, Vancouver, BC, Canada; Lauren Yee, St. Paul's Hosp, Vancouver, BC, Canada; Shubhayan Sanatani, British Columbia, Vancouver, BC, Canada

1:30 PM

Board # 2023

New-Onset Ventricular Tachycardia After Cardiac Surgery: Retrospective Analysis on its Incidence and Predictors of Long-Term Mortality

**Nam Gi-Byoung** , Min Soo Cho, Min Su Kim, Ungjeong Do, Asan Medical Ctr, Seoul, Korea, Republic of; Jun Kim, Asan Medical Ctr, Seoul; Kee-joon Choi, You-Ho Kim, Asan Medical Ctr, Seoul, Korea, Republic of

1:30 PM

Board # 2024

Age and Myocardial Infarction History Are Associated With the Amount of Cardiac Memory Developed in Response to Right Ventricular Pacing

**Kazi T Haq** , Erick A Alday, Oregon Health Science Univ, Portland, OR; Jian Cao, Medtronic Inc., Minneapolis, MN; Larisa G Tereshchenko, Oregon Health and Science Universit, Portland, OR

1:30 PM

Board # 2025

Arrhythmias and In-hospital Mortality Among Patients Admitted for Takotsubo Syndrome and Anterior Myocardial Infarction: A Retrospective Large-scale Study

**Maria Pia del Corral** , Univ' degli Studi di Milano, Milano, Italy; Giovanni Malanchini, Univ degli Studi di Milano, Milano, Italy; Pedro Covas, George Washington Univ, Washington, DC; Dorys Chavez, George Washington Univ, Washington DC, DC; Francesco Ambrosini, Univ degli studi di Milano, Serra Ricco, Italy; Federico Lombardi, H. San Paolo, Milan, Italy

# Abstract Poster Session

## WS.APS.03 - Women and CVD

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3123

Gender Differences in the Prevalence of Fragmented QRS Complex in Patient Populations With Different Risk Profiles

**Anette E. Haukilahti** , Tuomas V Kenttä, Lauri Holmstroem, Juha Vähätalo, Jani T Tikkanen, Henri K Terho, Samuli Lepojärvi, Juha S Perkiömäki, Medical Res Ctr Oulu, Univ of Oulu, Oulu, Finland; Olli Anttonen, Päijät-Häme Central Hosp, Lahti, Finland; Aapo L Aro, Tuomas Kerola, Helsinki Univ Hosp, Helsinki, Finland; Harri Rissanen, Natl Inst for Health and Welfare, Helsinki, Finland; Paul Knekt, Natl Inst for Health and Welfare, Oulu, Finland; M. Juhani Junttila, Heikki V. Huikuri, Medical Res Ctr Oulu, Univ of Oulu, Oulu, Finland

1:30 PM

Board # 3125

Trends and Outcomes of Arrhythmias in Hospitalized Patients With Breast Carcinoma: A National Population Based Study

Harsh Mehta, **Saad Amin** , Saint Barnabas Medical Ctr, Livingston, NJ; Ishani Shah, St. Joseph's Hosp and Medical Ctr, Phoenix, AZ; Akhtar Amin, Univ Hosp, Newark, NJ; Mohit Pahuja, Wayne State Univ, Detroit, MI; Keith A. Hawthorne, Diagnostic & Clinical Cardiology, West Orange

1:30 PM

Board # 3126

Migraine History Predicts Worse Angina but Not Coronary Vascular Dysfunction: Results From the Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction Study

**Jessica Siak** , Chrisandra L Shufelt, Galen Cook-Wiens, Bruce Samuels, Cedars-Sinai Medical Ctr, Los Angeles, CA; John W Petersen, R David Anderson, Eileen M Handberg, Carl J Pepine, Univ of Florida, Gainesville, FL; C. Noel Bairey Merz, Janet Wei, Cedars-Sinai Medical Ctr, Los Angeles, CA

1:30 PM

Board # 3127

Serum Uric Acid Levels Are Associated With Peripheral Endothelial Dysfunction in Women

**Jaskanwal Deep Singh S. Sara** , Riad Taher, Megha Prasad, Nikhil Kolluri, Lilach O Lerman, Amir Lerman, Mayo Clinic, Rochester, MN

1:30 PM

Board # 3128

Sleep Restriction Impairs Endothelial Cell Antioxidant Response

**Riddhi Shah** , Memet Emin, Su Gao, Sanja Jelic, Columbia Univ Irving Medical Ctr, New York, NY

1:30 PM

Board # 3129

Biomass Fuel Use and Cardiac Function in Nepali Women

**Catherine P Benziger** , Essentia Health, Duluth, MN; Jasleen Tiwana, Laura Hooper, Univ of Washington, Seattle, WA; Karl Pope, Univ of California Berkeley, Berkeley, CA; Vijay Alurkar, Manipal Coll of Medical Sciences & Manipal Teaching Hosp, Phulbari, Pokhara, Nepal; Ramchandra Kafle, Manipal Coll of Medical Sciences and Manipal Teaching Hosp, Phulbari, Pokhara, Nepal; Tula R Sijali, Inst for Social and Environmental Res -Nepal, Fulbari, Chitwan, Nepal; John Balmes, Univ of California San Francisco, Berkeley, CA; Joel Kaufman, Univ of Washington, Seattle, WA; Michael Bates, Univ of California Berkeley, Berkeley, CA

1:30 PM

Board # 3130

Low Body Mass Index Independently Predicts Future Risk of Elevated Low-density Lipoprotein Cholesterol Levels in Apparently Healthy Women

**Aiko Sakamoto** , Univ of Tokyo Graduate Sch of Med, Tokyo, Japan; Shintaro Yanagimoto, Univ of Tokyo, Tokyo, Japan; Kimie Tanaka, Issei Komuro, Univ of Tokyo Graduate Sch of Med, Tokyo, Japan; Kazuhiko Koike, Univ of Tokyo, Tokyo, Japan

1:30 PM

Board # 3131

Knowledge versus Perceptions: The Importance of Perceived Cardiovascular Risk on Behavior Change Attempts Among Women Veterans

Melissa Farmer, Julian Brunner, VA Greater Los Angeles Health Sys, North Hills, CA; Catherine Chanfreau, VA Greater Los Angeles Health Sys, Los Angeles, CA; Jessica L Moreau, VA Greater Los Angeles Health Sys, North Hills, CA; Tannaz Moin, Karen E Dyer, Alexis K Huynh, VA Greater Los Angeles Health Sys, Los Angeles, CA; Catherine A Schweizer, VA Greater Los Angeles Health Sys, North Hills, CA; Erin Finley, VA South Texas Health Sys, San Antonio, TX; Alison Hamilton, VA Greater Los Angeles Health Sys, Los Angeles, CA; **Bevanne Bean-Mayberry** , VA Greater Los Angeles Health Sys, North Hills, CA

1:30 PM

Board # 3132

Gender Differences in Industry Payments Among Cardiologists

**Inbar Raber** , Beth Israel Deaconess Medical Ctr, Boston, MA; Cian P. McCarthy, Massachusetts General Hosp, Boston, MA; Mahmoud S Al Rifai, Univ of Kansas, Wichita, KS; Muthiah Vaduganathan, Brigham and Women's Hosp, Boston, MA; Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD; Malissa J Wood, Massachusetts General Hospita, Boston, MA; Yvonne Smyth, Univ Coll Hosp Galway, Galway, Ireland; Nasrien E. Ibrahim, Doreen DeFaria Yeh, Massachusetts General Hosp, Boston, MA; Aarti Asnani, Beth Israel Deaconess Medical Ctr, Boston, MA; Roxana Mehran, Icahn Sch of Med Mt Sinai, New York, NY; John W. McEvoy, Natl Univ of Ireland, Galway, Galway, Ireland

# Abstract Oral Session

## PH.AOS.478 - Cournand and Comroe Early Career Investigator Award Competition

#### 102AB

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Vinicio A De Jesus Perez, Palo Alto, CA

2:00 PM

Moderator

Marina Del Rios, Chicago, IL

2:00 PM

Novel Rodent Model of Exercise-induced Pulmonary Hypertension (EIPH) in Heart Failure With Preserved Ejection Fraction

**Taijyu Satoh** , Longfei Wang, Vascular Med Inst, Univ of Pittsburgh, Pittsburgh, PA; Charles F McTiernan, Andrea Levine, Univ of Pittsburgh, Pittsburgh, PA; Scott Hahn, Jeff Baust, Vascular Med Inst, Univ of Pittsburgh, Pittsburgh, PA; Samuel Wyman, Nathan Salamacha, Rangos Res Ctr Animal Imaging Core and Developmental Biology, Univ of Pittsburgh, Pittsburgh, PA; Yijen L Wu, Cynthia St Hilaire, Univ of Pittsburgh, Pittsburgh, PA; Dmitry Goncharov, Vascular Med Inst, Univ of Pittsburgh, Pittsburgh, PA; Elena Goncharova, Adam C Straub, Univ of Pittsburgh, Pittsburgh, PA; Yen Chun Lai, Indiana Univ, Indianapolis, IN; Mark T Gladwin, Univ of Pittsburgh, Pittsburgh, PA

2:10 PM

Q & A

2:15 PM

NEDD9 Regulates Platelet-endothelial Adhesion and Pulmonary Arterial Thrombosis: Implications for Chronic Thromboembolic Pulmonary Hypertension

**George A Alba** , Massachusetts General Hosp, Boston, MA; Andriy Samokhin, Ying-Yi Zhang, Bradley M Wertheim, Elena Arons, Brigham and Women's Hosp, Boston, MA; Edward A Greenfield, Dana Farber Cancer Inst, Boston, MA; Martina H Lundberg Slingsby, Julia R Ceglowski, Frederick P Bowman, Brigham and Women's Hosp, Boston, MA; Yen-Rei Yu, John C Haney, Duke Univ, Durham, NC; George Eng, Massachusetts General Hosp, Boston, MA; Richard N Mitchell, Anthony Sheets, Brigham and Women's Hosp, Boston, MA; Sachiko Seo, Univ of Tokyo, Tokyo, Japan; Richard N Channick, UCLA, Los Angeles, CA; Peter J Leary, Univ of Washington, Seattle, WA; Sudarshan Rajagopal, Duke Univ, Durham, NC; Joseph Loscalzo, Elisabeth Battinelli, Bradley A Maron, Brigham and Women's Hosp, Boston, MA

2:25 PM

Q & A

2:30 PM

Clinical Implications of Respiratory Failure in Patients Receiving Durable Left Ventricular Assist Devices for End Stage Heart Failure

**P. Elliott Miller** , Cesar Caraballo, Neal G. Ravindra, Catherine Mezzacappa, Megan McCullough, Jadry Gruen, Andrew Levin, Samuel Reinhardt, Ayyaz Ali, Nihar R. Desai, Tariq Ahmad, Yale Univ, New Haven, CT

2:40 PM

Q & A

2:45 PM

Supra-coronary Aortic Banding Improves Right Ventricular Function in the Monocrotaline Rat Model of Pulmonary Arterial Hypertension

**Ping Yu Xiong** , Lian Tian, Elahe Alizadeh, Francois Potus, Ashley Martin, Stephen L Archer, Queen's Univ, Kingston, ON, Canada

2:55 PM

Q & A

3:00 PM

H19/EZH2 Axis: A New Biomarker and Therapeutic Target in Right Ventricular Failure Associated With Pulmonary Arterial Hypertension

**Junichi Omura** , Karima Habbout, Tsukasa Shimauchi, Sandra Breuils-Bonnet, Eve Tremblay, Sandra Martineau, Valerie Nadeau, Kassandra Gagnon, Francois Potus, Stephen L Archer, Roxane Paulin, Steeve Provencher, Olivier Boucherat, Sebastien Bonnet, Laval university, Quebec City, QC, Canada

3:10 PM

Q & A

# Abstract Oral Session

## CH.AOS.483 - Fontan Circulation: Improved Understanding of Long-Term Outcomes and Screening Measures

#### 111AB

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Anitha Sara John, Washington, DC

2:00 PM

Moderator

Salil Ginde, Milwaukee, WI

2:00 PM

Peripheral Venous Pressure Responses During Exercise Are Predictive of Adverse Fontan Outcomes

**Kathleen Colman** , Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; Gruschen Veldtman, King Faisal Specialist Hosp, Riyadh, Saudi Arabia; Tarek Alsaied, Adam M Lubert, Clifford Chin, Wayne Mays, Sandra K Knecht, Danielle Poe, Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH

2:10 PM

Q & A

2:15 PM

Magnetic Resonance Elastography is Associated With Fontan Failure and Radiologic Portal Hypertension

**Tarek Alsaied** , Mathias Possner, Cincinnati Children's Hosp, Cincinnati, OH; Adam Lubert, Cincinnati Children's Hosp, Cincinnati, OH; Andrew T Trout, Joseph Palermo, Angela Lorts, Bryan H Goldstein, Gruschen Veldtman, Jonathan R Dillman, Cincinnati Children's Hosp, Cincinnati, OH

2:25 PM

Q & A

2:30 PM

Hepatic Extracellular Volume Fraction is Elevated in Patients With a Fontan Palliation: A Potential Marker of Liver Fibrosis Obtained During Cardiac Scanning

**Lidija Breznikar McGrath** , Oregon Health and Science Universit, Portland, OR; Ryan C Van Woerkom, Univ of Texas Southwestern, Dallas, TX; Stephen B Heitner, Oregon Health and Science U, Portland, OR; Michael Jerosch-Herold, Brigham and Women's Hosp, Boston, MA; Craig Stanford Broberg, Knight Cardiovascular Inst, Portland, OR

2:40 PM

Q & A

2:45 PM

Adolescents and Adults With a Fontan Circulation Have Worse Cognitive Outcomes Than Individuals With Repaired Transposition of the Great Arteries and Healthy Matched Controls

**Charlotte E Verrall** , Children's Hosp at Westmead, Sydney, Australia; Diana Zannino, Murdoch Children's Res Institu, Parkville; Yufei Jiang, Univ of Melbourne, Melbourne, Australia; Karin Du Plessis, Murdoch Children's Res Inst, Melbourne, Australia; David Celermajer, Royal Prince Alfred hospital, Sydney, Australia; Yves d'Udekem, Royal Childrens Hosp, Melbourne, Belgium; David S Winlaw, The Children's Hosp at Westmead, Sydney, Australia; Rachael L Cordina, Royal Prince Alfred Hosp, Sydney, Australia

2:55 PM

Q & A

3:00 PM

Non-invasive Cardiac System (NICaS) Derived Resting and Exercise-augmented Hemodynamic Parameters From Patients With Fontan Circulation

Pedram Hassan-Tash, Gurkirat Chana, David Kent, St Boniface Hosp, Winnipeg, MB, Canada; C Nolan Turnbull, Meaghan Rempel-Ewharekuko, Nicole Johnston, Univ of Manitoba, Winnipeg, MB, Canada; Brett Hiebert, Robin Ducas, St Boniface Hosp, Winnipeg, MB, Canada; James W Tam, JWTAM Medical Corp, Winnipeg, MB, Canada; Todd Duhamel, Univ of Manitoba, Winnipeg, MB, Canada; **Ashish H Shah** , St Boniface Hosp, Winnipeg, MB, Canada

3:10 PM

Q & A

# Abstract Oral Session

## VA.AOS.516 - Jay D. Coffman Early Career Investigator Competition

#### 105AB

### Saturday, November 16, 2019, 2:00 PM - 2:45 PM

2:00 PM

Moderator

Peter Henke, Ann Arbor, MI

2:00 PM

Higher Perceived Stress Levels are Associated With an Increased Long-Term Mortality Risk: A Landmark Analysis in Patients With Peripheral Artery Disease

**Ali O Malik** , Saint Lukes Mid America Heart Inst, Kansas City, MO; Poghni Allen Peri-Okonny, Saint Luke's Mid America Heart Inst, Kansas city, MO; Kensey Gosch, Saint Luke's Hosp, Kansas City, MO; Merrill Thomas, Saint Luke's Mid America Heart Inst, Kansas City, MO; Carlos Mena, Yale Univ, New Haven, CT; William R Hiatt, Univ of Colorado, Aurora, CO; Phillip Jones, Saint Lukes Mid America Heart Inst, Kansas City, MO; Jeremy Provance, UMKC Sch of Med, Kansas City, MO; Clementine Labrosciano, Univ of Adelaide, Woodville, SA, Australia; John Spertus, Mid America Heart Inst, Kansas City, MO; Kim Smolderen, St Lukes Mid America Heart Inst, Kansas City, MO

2:10 PM

Q & A

2:15 PM

Increased TGFβ1 Signaling, Fibrosis and Circulating Cell Infiltration of Female Graft Veins Contribute to Sex Differences in Murine Arteriovenous Fistulas

**Chuanqi Cai** , Chenglei Zhao, Sreenivasulu Kilari, Amit Sharma, Binxia Yang, Avishek Singh, Michael Simeon, Avi Misra, Mayo Clinic, Rochester, MN; Li Yiqing, Union Hosp, Wuhan, China; Rajiv Kumar, Sanjay Misra, Mayo Clinic, Rochester, MN

2:25 PM

Q & A

2:30 PM

Utilization and Outcomes of Catheter-directed Thrombolysis for Acute Pulmonary Embolism: A Nationwide Cohort Study

**Sebastian E Beyer** , Colby Shanafelt, Duane S Pinto, Beth Israel Deaconess Medical Ctr, Boston, MA; Jeffrey Weinstein, Beth Israel Deaconess Medical Ctr, BOSTON, MA; Herbert D Aronow, Alpert Medical Sch of Brown Univ, Providence, RI; Ido Weinberg, Massachusetts General Hosp, Boston, MA; Robert W Yeh, Beth Israel Deaconess Med Ctr, Boston, MA; Eric A Secemsky, Beth Israel Deaconess Medical Cente, Boston, MA; Brett Carroll, Brigham and Women's Hosp, Boston, MA

2:40 PM

Q & A

# Abstract Oral Session

## IM.AOS.511 - Melvin Judkins Early Career Investigator Competition

#### 108B

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

J Kevin K Demarco, Bethesda, MD

2:10 PM

Q & A

2:15 PM

Long-term Embolic Outcomes After Detection of Left Ventricular Thrombus by Late Gadolinium Enhancement Cardiovascular Magnetic Resonance Imaging: A Matched Cohort Study

**Pratik S Velangi** , Christopher S Choo, Univ of Minnesota, Minneapolis, MN; Ko-Hsuan Chen, Univ of Minnesota, San Jose, CA; Felipe Kazmirczak, Prabhjot S Nijjar, Osama Okasha, Mehmet Akcakaya, Chetan Shenoy, Univ of Minnesota, Minneapolis, MN

2:25 PM

Q & A

2:30 PM

**A Deep Learning-Based Cardiovascular Magnetic Resonance Native T** 1 **Scar Prediction Model in Hypertrophic Cardiomyopathy**

**Ulf Neisius** , Beth Israel Deaconess Medical Ctr, Boston, MA; Ahmed Fahmy, BIDMC-Harvard Univ, Boston, MA; Hossam El-Rewaidy, Shiro Nakamori, Beth Israel Deaconess Medical Ctr, Boston, MA; Warren J Manning, Beth Israel Deaconess Med Ctr, Boston, MA; Reza Nezafat, Beth Israel Deaconess Medical Ctr, Boston, MA

2:40 PM

Q & A

2:45 PM

Impaired Stress Myocardial Oxygenation and Not Perfusion Reserve is Associated With Arrhythmic Risk in Hypertrophic Cardiomyopathy: Insights From a Novel Oxygen Sensitive Cardiac Magnetic Resonance Approach

**Betty Raman** , Kenneth Chan, Rina Ariga, Univ of Oxford, Oxford, United Kingdom; Masliza Mahmod, Univ of Oxford, Oxford; Moritz Hundertmark, Sanjay Sivalokanathan, Univ of Oxford, Oxford, United Kingdom; Theodoros D Karamitsos, Aristotle Univ of Thessaloniki, Thessaloniki, Greece; Joseph Selvanayagam, Flinders Medical Ctr, Adelaide, SA, Australia; Aaron Hess, Elizabeth Tunnicliffe, Hugh Watkins, Stefan Neubauer, Univ of Oxford, Oxford, United Kingdom

2:55 PM

Q & A

3:00 PM

Wave Propagation Through Systemic Vasculature is Abnormal in Patients With Fontan Circulation and Correlates With Functional Exercise Indices

**Michal Schafer** , Children's Hosp Colorado, Aurora, CO; Benjamin Frank, UC Denver - Anschutz Medical, Aurora, CO; Roni Jacobsen, Children's Hosp Colorado, Aurora, CO; Christopher Rausch, Colorado Childrens Hosp, Aurora, CO; Max B Mitchell, Univ of Colorado, Aurora, CO; James Jaggers III, Childrens Hosp Colorado, Aurora, CO; Lorna Browne, Children's Hosp Colorado, Aurora, CO; Alexander J Barker, Children's Hosp Colorado, Denver, CO; Kendall S Hunter, The Childrens Hosp, Aurora, CO; Dunbar D Ivy, Univ of Colorado, Aurora, CO; Adel K Younoszai, Childrens Hosp Colorado, Aurora, CO

3:10 PM

Q & A

# Abstract Oral Session

## LF.AOS.567 - Nutrition: Novel Insights and Controversies

#### 204AB

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Penny M Kris-Etherton, University Park, PA

2:00 PM

Intermittent Fasting Lifestyle and Incidence of Heart Failure and Myocardial Infarction in Cardiac Catheterization Patients

**Ciera Bartholomew** , Brigham Young Univ, Provo, UT; Joseph Brent Muhlestein, Jeffrey L Anderson, Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT; Heidi T May, Kirk Knowlton, Tami L Bair, Intermountain Medical Ctr, Salt Lake City, UT; Viet T Le, Intermountain Medical Ctr, Rocky Mountain Univ of Health Professions, Salt Lake City, UT; Bruce Bailey, Brigham Young Univ, Provo, UT; Benjamin D Horne, Intermountain Heart Inst, Univ of Utah, Salt Lake City, UT

2:10 PM

Q & A

2:15 PM

Association Between Ultra-Processed Food Intake and Cardiovascular Health Among US Adults: NHANES 2011-2016

**Zefeng Zhang** , CDC, Atlanta, GA; Sandra Jackson, CDC, Chamblee, GA; Euridice Martinez, Univ of São Paulo, Brazil, São Paulo, Brazil; Cathleen Gillespie, Quanhe Yang, CDC, Atlanta, GA

2:25 PM

Q & A

2:30 PM

A Plasma Phospholipid Omega-3 Fatty Acid Index > 4% Prevents Cognitive Decline in Cognitively Healthy Subjects With Coronary Artery Disease

**Bhavya Vemuri** , Beth Israel Deaconess Medical Ctr/ Harvard Medical Sch, Boston, MA; Abdulaziz Malik, Boston Medical Coll, Boston, MA; Abdul Aziz A Asbeutah, Beth Israel Deaconess Medical Ctr/ Harvard Medical Sch, Boston, MA; Francine K Welty, Harvard Medical Ctr, Brookline, MA

2:40 PM

Q & A

2:45 PM

Evening Caloric Intake is Associated With Cardiovascular Health in Women: Results From the American Heart Association Go Red for Women Strategically Focused Research Network

**Nour Makarem** , Columbia Univ Medical Ctr, New York, NY; Dorothy D Sears, Arizona State Univ, Phoenix, AZ; Marie-Pierre St-Onge, Columbia Univ, New York, NY; Sheila F Castaneda, San Diego State Univ, Chula Vista, CA; Linda Gallo, San Diego State Univ, San Diego, CA; Gregory Anthony Talavera, San Diego State Univ, Chula Vista, CA; Ming Liao, CUMC, New York, NY; Stephanie Byun, Zara Mayat, Faris Michael Zuraikat, Brooke A Aggarwal, Columbia Univ Medical Ctr, New York, NY

2:55 PM

Q & A

3:00 PM

Replacing Saturated Fats With Unsaturated Fats From Walnuts or Vegetable Oils Favorably Affects Lipoprotein Classes Without Increasing Lipoprotein (a)

**Alyssa Tindall** , Penn State Univ, University Park, PA; Penny M Kris-etherton, Pennsylvania State Univ, University Park, PA; Kristina Petersen, The Pennsylvania State Univ, University Pk, PA

3:10 PM

Q & A

# Abstract Oral Session

## LF.AOS.485 - Robert Levy Memorial Lecture and Lifestyle and Cardiometabolic Health Early Career Investigator Award Competition

#### 201AB

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Penny M Kris-etherton, University Park, PA

2:00 PM

Moderator

Howard S Weintraub, New York, NY

2:00 PM

Moderator

Sergio Fazio, Portland, OR

2:00 PM

Robert Levy Memorial Lecture

Frank M Sacks, Boston, MA

2:25 PM

Q & A

2:30 PM

Effects of Canagliflozin in Patients With Type 2 Diabetes and Chronic Heart Failure: A Randomized Clinical Trial (CANDLE)

**Atsushi Tanaka** , Saga Univ, Saga, Japan; Itaru Hisauchi, Isao Taguchi, Dokkyo Medical Univ Saitama Medical Ctr, Koshigaya, Japan; Akira Sezai, Nihon Univ Sch of Med, Tokyo, Japan; Shigeru Toyoda, Dokkyo Medical Univ, Mibu, Japan; Masataka Sata, Tokushima Univ Graduate Sch, Tokushima, Japan; Shinichiro Ueda, Univ of the Ryukyus, Nishihara-cho, Japan; Jun-ichi Oyama, Saga Univ, Saga, Japan; Masafumi Kitakaze, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Toyoaki Murohara, Nagoya Univ Graduate Sch of Med, Nagoya, Japan; Koichi Node, Saga Univ, Saga, Japan

2:40 PM

Q & A

2:45 PM

A Randomized Trial of Exercise versus Low-energy Meal Replacement Diet to Improve Cardiac Dysfunction in Working-Age Adults With Type 2 Diabetes

**Gaurav S Gulsin** , Daniel J Swarbrick, Lavanya Athithan, Emer M Brady, Joseph J Henson, Emma Baldry, Stavroula Argyridou, Anna-Marie Marsh, Gareth Squire, Nishal B Jaicim, Univ of Leicester, Leicester, United Kingdom; John Biglands, Leeds NIHR Biomedical Res Ctr, Leeds, United Kingdom; Thomas Yates, Kamlesh Khunti, Melanie J Davies, Univ of Leicester, Leicester, United Kingdom; Gerry McCann, Univ of Leicester, Leicester

2:55 PM

Q & A

3:00 PM

Associations Between Physical Activity, Subclinical Myocardial Injury, and Cardiovascular Mortality in the General Population

**Charles A German** , Wake Forest Baptist Medical Ctr, Winston Salem, NC; Muhammadimtiaz Ahmad, Wake Forest Sch of Med, Winston Salem, NC; Yabing Li, Wake Forest Sch of Medcine, Winston salem, NC; Elsayed Z Soliman, Wake Forest Sch of Med, Winston Salem, NC

3:10 PM

Q&A

# Cardiovascular Seminar

## EP.CVS.557 - Atrial Fibrillation: From Wearables to Guidelines

#### 201C

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Steven Lubitz, Boston, MA

2:00 PM

Moderator

Renate B Schnabel, Hamburg, Germany

2:00 PM

The Evolving Epidemiology of Atrial Fibrillation in the Era of Wearable Monitors

Prashanthan Sanders, Norwood, Australia

2:12 PM

Detection of Atrial Fibrillation Captured by Wearable Devices: Looking for the Needle in the Haystack?

Larry R Jackson II, Durham, NC

2:24 PM

Early Detection of Atrial Fibrillation: An Opportunity for Prevention of Stroke and Heart Failure

David McManus, MA

2:36 PM

The Evidence Behind Use of Wearable Devices to Screen for Atrial Fibrillation: The Apple Heart Study

Marco Perez, Stanford, CA

2:48 PM

Downstream Economic Burden of Early Detection of Atrial Fibrillation by Wearable Devices: Is the Cost Worth the Squeeze?

Paul A Heidenreich, Palo Alto, CA

3:00 PM

Screening for Atrial Fibrillation Using Wearable Devices: Where Do We Stand With the GuideLines?

Sana M Al-Khatib, Durham, NC

3:12 PM

Q & A

# Cardiovascular Seminar

## HY.CVS.420 - Blood Pressure Measurement in Humans: An Overview of the 2019 Scientific Statement from AHA

#### 108A

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Daichi Shimbo, New York, NY

2:00 PM

Moderator

Paul Muntner, Birmingham, AL

2:00 PM

Testing Knowledge of the AHA Scientific Statement Using Audience Response

Marwah Abdalla, New York, NY

2:15 PM

Introduction to Session

Paul Muntner, Birmingham, AL

2:20 PM

Demystifying Blood Pressure Device Validation

Jordana Cohen, Philadelphia, PA

2:30 PM

Best Approach for Office Blood Pressure Measurement

Trudy R Gaillard, Miami, FL

2:45 PM

Best Approach for Ambulatory Blood Pressure Monitoring

Jackson T Wright Jr., Cleveland, OH

3:00 PM

Best Approach for Home Blood Pressure Monitoring

Raymond R Townsend, Philadelphia, PA

# Cardiovascular Seminar

## NR.CVS.42 - Caregiving Across the Continuum of CVD

#### 118C

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

moderator

Lisa Kitko, University Park, PA

2:00 PM

moderator

Anna Strömberg, Linköping, Sweden

2:00 PM

Caregiving After an Acute Event: A Period of Increased Vulnerability?

Judith E Hupcey, Hershey, PA

2:18 PM

Caregiving During Chronic Illness

Julie T Bidwell, Sacramento, CA

2:36 PM

Caregiving at the End of Life

Nicholas Dionne-Odom, Birmingham, AL

2:54 PM

Are Caregivers Sacrificing Their Own Health?

Colleen K McIlvennan, Aurora, CO

3:12 PM

Discussion

# Cardiovascular Seminar

## IN.CVS.412 - Complications in the Cath Lab: Opportunities to Learn

#### 107AB

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Binita Shah, New York, NY

2:00 PM

Moderator

Ali E Denktas, Houston, TX

2:00 PM

Panel Participant

alaide Chieffo, Milan, Italy

2:00 PM

Panel Participant

Mamas Mamas, keele

2:00 PM

Panel Participant

Saif Anwaruddin, Philadelphia, PA

2:00 PM

A Calcified Nightmare

Arasi Maran, N. Charleston, SC

2:08 PM

Panel Discussion

2:15 PM

Why Did This Valve Have to Happen to Me???

Homam Ibrahim, New York, NY

2:23 PM

Panel Discussion

2:30 PM

I've Had Enough of This Leg

Claudia C Serrano, New York, NY

2:38 PM

Panel Discussion

2:45 PM

It Was Called a CHIP Case for a Reason

Ravi Subhash Hira, Seattle, WA

2:53 PM

Panel Discussion

3:00 PM

Yikes! The ACS Case That Went Wrong

Helena Tizón-Marcos, Barcelona

3:08 PM

Panel Discussion

# Cardiovascular Seminar

## CH.CVS.414 - Congenital Aortic Valve Disease

#### 112AB

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Brian Boe, Columbus, OH

2:00 PM

Moderator

Kristine J Guleserian, Miami, FL

2:00 PM

Case presentation

James F Cnota, Cincinnati, OH

2:15 PM

Imaging, Counseling, and Management of Fetal Aortic Stenosis

Lindsay R Freud, New York, NY

2:30 PM

The Case for Sugical Management of Neonatal Aortic Stenosis

Mathieu Vergnat, Tremblay, France

2:45 PM

Managing Bicuspid Aortic Valve Disease in the Clinic

Richard V WILLIAMS, Salt Lake City, UT

3:00 PM

TAVR for Congenital Aortic Valve Disease

Athar M Qureshi, Houston, TX

# Cardiovascular Seminar

## AC.CVS.430 - Debates in Cardiogenic Shock

#### 103A

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Ileana L Pina, Cleveland Hghts, OH

2:00 PM

Moderator

George D Dangas, New York, NY

2:00 PM

Pro: Unloading the LV in Cardiogenic Shock: Ready for Prime Time

Navin K KAPUR, Hanover, MA

2:08 PM

Con: Time is Muscle: Just Open the Infarct Related Artery

Vladimir Dzavik, Toronto, ON, Canada

2:24 PM

Con: Deferred Surgery is Preferred in Patients With Mechanical Complications

Michael Zhen-Yu Tong, Cleveland, OH

2:32 PM

Pro: Patients With STEMI Complicated by Out of Hospital Cardiac Arrest Should Undergo Emergent Revascularization

Christian Spaulding, Paris, France

2:40 PM

Con: Only Selective Patients Following Out of Hospital Cardiac Arrest Should Undergo Emergent Angiography

Duane Pinto, Boston, MA

2:48 PM

Pro: I Still Use the IABP on Occasion in Cardiogenic Shock

Timothy D Henry, Cincinnati, OH

2:56 PM

Con: No Role for IABP in the Current Management of Cardiogenic Shock

Holger Thiele, Leipzig

3:04 PM

Discussion

# Cardiovascular Seminar

## QU.CVS.494 - Electronic Health Records: The Agony and the Ecstasy

#### 202AB

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Ann Marie Navar, Durham, NC

2:00 PM

Moderator

Srinath Adusumalli, Philadelphia, PA

2:00 PM

Electronic Health Records: Introduction to the Session

Tariq Ahmad, New Haven, CT

2:12 PM

Operational and Clinical Benefits of EHRs

Alison Fox-Robichaud, Hamilton, ON, Canada

2:24 PM

Me and My EHR: Clinicians' Love-hate Relationship With Their Computers

Christine Sinsky, IA

2:36 PM

The Future of the Electronic Health Record: Next Generation Technology

Raj Ratwani, Washington, DC

2:48 PM

Do Electronic Health Records Improve Health Care Quality?

Senthil Selvaraj, Philadelphia, PA

3:00 PM

Panel Participant

Alison Fox-Robichaud, Hamilton, ON, Canada

3:00 PM

Panel Participant

Christine Sinsky, IA

3:00 PM

Panel Participant

Raj Ratwani, Washington, DC

3:00 PM

Panel Discussion

# Cardiovascular Seminar

## EA.CVS.459 - Real Life Case Demonstrations - What Happens in the EP Lab Doesn't Stay in the EP Lab

#### 113BC

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

David J Callans, Washington Crossing, PA

2:00 PM

Moderator

Andrew E Epstein, Philadelphia, PA

2:00 PM

Ventricular Tachycardia Ablation With Impella Support - Practical Implementation for Routine Use

Oussama Wazni, Cleveland, OH

2:15 PM

Q&A

2:18 PM

VT Mapping and Ablation

Francis E Marchlinski, Bala Cynwyd, PA

2:33 PM

Q&A

2:36 PM

His Bundle Pacing - Tips and Pearls

pugazhendhi Vijayaraman, Wilkes Barre, PA

2:51 PM

Q&A

2:54 PM

Atrial Fibrillation Ablation

Andrea Natale, Austin, TX

2:00 PM

Panel Participant

Melissa Robinson, Seattle, WA

2:00 PM

Panel Participant

William G STEVENSON, Nashville, TN

2:00 PM

Panel Participant

Pamela Mason

# Cardiovascular Seminar

## ST.CVS.161 - The Brain-Heart Axis: Discussions in Neurocardiogenic Syndromes

#### 118A

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Sara Aspberg, 182 88 Stockholm, Sweden

2:00 PM

Moderator

Maria Cecilia Bahit, Rosario, Argentina

2:00 PM

Anatomy and Physiology of the Brain & Heart Axis

Max J Hilz, Erlangen, Germany

2:15 PM

Myocardial Stunning After Stroke

Santosh Murthy, new york, NY

2:30 PM

Takotsubo Cardiomyopathy: Pathophysiology & Treatment

Dana Dawson, Edinburgh, United Kingdom

2:45 PM

Stroke-Related Myocardial Injury and Cardiac Arrhythmias

Luciano Sposato, London, ON, Canada

3:00 PM

Voodoo Death: Myth or Reality

Mary Sheppard, London, United Kingdom

# Cardiovascular Seminar

## SA.CVS.350 - The War Room Returns: Best Plan of Attack for Quality Outcomes...Let the Debates Continue!

#### 109AB

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Michael P Fischbein, Stanford, CA

2:00 PM

Moderator

Stephanie MPN Fuller, Philadelphia, PA

2:00 PM

Type A Dissection - All Should Be Treated With Total Arch With Elephant Trunk

S Chris Malaisrie, Chicago, IL

2:09 PM

Type A Dissection- All Should Be Treated With Hemi-Arch Replacement

Derek Brinster, New York, NY

2:18 PM

Mitral Stenosis With MAC Should Be Treated With a Minimally Invasive Transcatheter Aortic Valve

Tom C Nguyen, Houston, TX

2:27 PM

Mitral Stenosis With MAC Should Be Treated With Open Surgical Mitral Valve Replacement

adanna akujuo, Albany, NY

2:36 PM

The Marginal Donor Lung Can Be Transplanted After Lung in a Box

gabriel Loor, Houstonr, TX

2:45 PM

Marginal Donor Lung Should Remain on the Wait List

Alexander Krupnick

2:54 PM

The 60 yo Patient With Severe AS and Small Aortic Root Should Be Treated With an Aortic Root Replacment

Bo Yang, Ann Arbor, MI

3:03 PM

The 60 yo Patient With Severe AS and Small Aortic Root Should Be Treated With an Aortic Root Enlargement Procedure

Duke Cameron, Boston, MA

3:12 PM

Discussion

# Early Career

## AC.EC.319 - CLCD Early Career CORE Session: Your Passion, Your Career, Your Growth ? Practical Advice from Mentors for The Fundamentals and Beyond

#### 103B

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Janice Chyou, New York, NY

2:00 PM

Moderator

Eric D Peterson, Chapel Hill, NC

2:00 PM

Mentorship: Building Your Mentoring Team, Being Mentored, and Becoming a Mentor

Linda D Gillam, Morristown, NJ

2:12 PM

Clinical Practice: Building Your Clinical Practice - From the Office to the Service Line, From Patients and Evolving Regulatory Stipulations

Patrick T O'Gara, Boston, MA

2:24 PM

Teaching: Teaching Trainees, Colleagues, Patients, and the Population at Large - Pearls and Opportunities

Eric N Prystowsky, Indianapolis, IN

2:36 PM

Research: as a Career or as a Collaborator - Opportunities and Pointers

Robert O Bonow, Chicago, IL

2:48 PM

Leadership and Self Development: A Journey Through Career Stages

Andrea M Russo, Camden, NJ

3:00 PM

Interactive Panel Discussions

3:00 PM

Panel Discussion

Linda D Gillam, Morristown, NJ

3:00 PM

Panel Discussion

Eric N Prystowsky, Indianapolis, IN

3:00 PM

Panel Discussion

Robert O Bonow, Chicago, IL

3:00 PM

Panel Discussion

Patrick T O'Gara, Boston, MA

3:00 PM

Panel Discussion

Andrea M Russo, Camden, NJ

# FIT Event

## FIT.17 - Getting Involved with the AHA as a Trainee

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Saturday, November 16, 2019, 2:00 PM - 2:45 PM

2:00 PM

Panel Discussion with Jared Magnani, MD, Jeff Hsu, MD PhD, Nosheen Reza, MD and Anum Saeed MD

This is not a CME/CE certified session

# Frontiers in Science

## EA.FIS.602 - Arrhythmia Research Summit: Novel Mechanisms Beget New Arrhythmia Therapies

#### 119AB

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Sanjiv M Narayan, Stanford, CA

2:00 PM

Moderator

Usha Tedrow, Boston, MA

2:00 PM

Keynote: New Druggable Targets for Arrhythmias

Dobromir Dobrev, Essen

2:10 PM

Q&A

2:12 PM

Mitochondrial Mechanisms and Targets for AF

Cevher Ozcan, Chicago, IL

2:17 PM

Q&A

2:18 PM

Targeting reactive metabolite scavengers for prevention of arrhythmias

Katherine MURRAY, Nashville, TN

2:23 PM

Q&A

2:24 PM

Targeting abnormal protein handling in management of arrhythmias

Bianca Brundel, Amsterdam

2:29 PM

Q&A

2:30 PM

Role of mitochondria in arrhythmogenesis

Brian O'Rourke, Baltimore, MD

2:35 PM

Q&A

2:36 PM

Genetic Testing Guided Antiarrhythmic Therapy

Michael Ackerman, Rochester, MN

2:41 PM

Q&A

2:42 PM

Mechanistic relationships between alcohol and AF

Gregory Marcus, San Francisco, CA

2:47 PM

Q&A

2:48 PM

Targeting the inward rectifier current as a safer antiarrhythmic drug

Marcel van der Heyden, Utrecht

2:53 PM

Q&A

2:54 PM

Reversing the AF Substrate

Dennis Lau, Adelaide, Australia

2:59 PM

Q&A

3:00 PM

Neuromodulation of ventricular arrhythmias

Marmar VASEGHI, Los Angeles, CA

3:05 PM

Q&A

3:06 PM

Functional Consequences of an AF GWAS Risk Locus

NANA Liu, Cleveland, OH

3:11 PM

Q&A

3:12 PM

Panel Discussion

# Hall

## EP.HT.05 - ECGs and EGMs in Real-Time

#### EP Central

### Saturday, November 16, 2019, 2:00 PM - 2:45 PM

2:00 PM

Moderator

Jonathan W Dukes, Santa Barbara, CA

2:00 PM

Panel Participant

Fred Kusumoto, Jacksonville, FL

2:00 PM

Panel Participant

Julia H Indik, Tucson, AZ

# Hall

## HT.02 - Remote Health Delivery: Telemedicine, eConsults and More

#### Health Innovation Pavilion, Heart Hub, Science and Technology Hall, Level 2

### Saturday, November 16, 2019, 2:00 PM - 3:00 PM

2:00 PM

Moderator

Larry A Allen, Aurora, CO

2:07 PM

Shifting Office-Based Care Online: eConsults and Remote Visits

Elizabeth A Jackson, Birmingham, AL

2:21 PM

Patient perspectives in telehealth

Greg Merritt, MI

2:28 PM

Quality and outcomes of telehealth programs

Scott Shipman, DC

2:00 PM

Moderator

Jedrek Wosik, Durham, NC

# Joint Sessions

## AC.JS.1617 - Global Roundtable: Acute Coronary Syndromes in 2019: The Caribbean- South American Perspective (Argentina Federation of Cardiology, Caribbean Cardiac Society, Chilean Society of Cardiology and Cardiovascular Surgery and National Heart Foundation Hospital)

#### 121A

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Long Term Betablockers post Myocardial and Cardiovascular Surgery

Juan Carlos Prieto, Santiago, Chile

2:15 PM

Challenges of Managing ACS in a Developing Country

Tawfiq Shahriar Huq, Dhaka, Bangladesh

2:30 PM

Anti-Thrombotic Therapies after PCI in AF Patients.

Hector Luciardi, Argentina

3:00 PM

Panel Discussion

# Late-Breaking Science

## LBS.02 - Late Breaking Science II: Results for the Ischemia Trials: To Intervene or Not to Intervene

#### Main Event I

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

RASHA KADEM AL-LAMEE, London

2:00 PM

Moderator

James A de Lemos, Dallas, TX

2:00 PM

Social Media Moderator

Elliott M Antman, Weston, MA

2:00 PM

Case Presentation

2:03 PM

Introduction

Elliott M Antman, Weston, MA

2:10 PM

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches: Primary Report of Clinical Outcomes

**Judith S Hochman** , NYU Sch of Med, New York, NY; ISCHEMIA Research Group

2:22 PM

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches: Primary Report of Quality of Life Outcomes

**John A. Spertus** , Mid America Heart Inst, Kansas City, MO; ISCHEMIA Research Group

2:29 PM

Discussant

Alice K Jacobs, Boston, MA

2:34 PM

International Study of Comparative Health Effectiveness With Medical and Invasive Approaches- Chronic Kidney Disease (ISCHEMIA-CKD): Primary Results of Clinical Outcomes

**Sripal Bangalore** , New York Univ Sch of Med, New York, NY; ISCHEMIA-CKD Research Group

2:44 PM

Discussant

Glenn N Levine, HOUSTON, TX

2:49 PM

Panel Discussion

2:49 PM

Panel Participant

Brahmajee Kartik Nallamothu, Ann Arbor, MI

2:49 PM

Panel Participant

Roxana Mehran, New York, NY

2:49 PM

Panel Participant

Alice K Jacobs, Boston, MA

2:49 PM

Panel Participant

Glenn N Levine, HOUSTON, TX

3:12 PM

Case Revisited

# Main Event

## AT.ME.135 - Clonal Hematopoiesis - CHIPing Away at CV Risk

#### Nutter Theatre

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Alan R Tall, New York, NY

2:00 PM

Moderator

Gwendalyn Randolph, St. Louis, MO

2:00 PM

Clonal Hematopoiesis: Clinical Cases and Cardiovascular Care

Amy Erica Lin, Boston, MA

2:15 PM

CHIP Mutations and Cardiovascular Risk: Commonalities with Cancer

Siddhartha Jaiswal, Stanford, CA

2:30 PM

JAK of All Trades - JAK2 in Thrombosis and Atherosclerosis

Trevor P Fidler, New York City, NY

2:45 PM

TET2 - A New Driver of Age-Related CVD

Jose Fuster, Spain

3:00 PM

Perspectives for the Future - How Will We Use CHIP Data in Practice?

Peter Libby, Boston, MA

# Main Event

## HF.ME.538 - Managing Diabetes in Heart Failure: Finding the Sweet Spot

#### Main Event II

### Saturday, November 16, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Shannon M Dunlay, Rochester, MN

2:00 PM

Moderator

Prakash C Deedwania, Fresno, CA

2:00 PM

Prevalence, Phenotype, and Prognosis of Heart Failure and Diabetes

Biykem Bozkurt, Houston, TX

2:12 PM

Diabetic Cardiomyopathy: Understanding the Mechanism Through Metabolic Pathways

Rong Tian, Seattle, WA

2:24 PM

SGLT2, DPP4, GLP1, Metformin: What's the Optimal Approach?

Subodh Verma, Toronto, ON, Canada

2:36 PM

Whose Responsibility is it to Prescribe Glycemic Agents?

Javed Butler, Atlanta, GA

2:48 PM

Know Diabetes by Heart" AHA Initiative

Robert H Eckel, Morrison, CO

3:00 PM

Case Presentation and Panel Discussion

Robert John Mentz, Hillsborough, NC

# Women's Professional Development

## WPD.01 - Storytelling with Louise McCullough, MD, PhD, FAHA

#### Go Red Women in Science & Medicine Lounge, Pennsylvania Convention Center, 2nd Floor, Heart Hub

### Saturday, November 16, 2019, 2:00 PM - 2:30 PM

This is not a CME/CE certified session

# Abstract Rapid Fire Oral

## CH.RFO6 - Clinical Interventional Cardiology & Electrophysiology

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 2:15 PM - 3:05 PM

2:15 PM

Moderator

Robert Harrison Pass, New York, NY

2:15 PM

Scoring System for Post Ligation Cardiac Syndrome and Its Utility After Transcatheter and Surgical Patent Ductus Arteriosus Ligation in Extremely Low Birthweight Infants

**Evan Harvey** , Unversity of Tennessee Health Science Ctr, Memphis, TN; Ranjit Philip, Univ of Tennessee Health Science Ctr, Memphis, TN; Benjamin Waller, Unversity of Tennessee Health Science Ctr, Memphis, TN; Jason Johnson, Univ of Tennessee Health Science Ctr, Memphis, TN; Jorden Cunningham, Le Bonheur Children's Hosp, Memphis, TN; Sandeep Chilakala, Univ of Tennessee Health Science Ctr, Memphis, TN; Mark Weems, Unversity of Tennessee Health Science Ctr, Memphis, TN; Leah Apalodimas, Le Bonheur Children's Hosp, Memphis, TN; Shyam Sathanandam, Unversity of Tennessee Health Science Ctr, Memphis, TN

2:20 PM

Q & A

2:25 PM

A Multicenter Analysis of Reintervention After Balloon Valvuloplasty for Critical Pulmonary Valve Stenosis

**David M Kwiatkowski** , Stanford Univ Sch of Med, Palo Alto, CA; Lynn Peng, Stanford Medical Ctr, Palo Alto, CA; Gregory Adamson, Stanford Univ Sch of Med, Palo Alto, CA; Ronnie T Collins, Stanford Univ, Palo Alto, CA

2:30 PM

Q & A

2:35 PM

Feasibility and Safety of Percutaneous Cardiac Interventions in 100 Consecutive Infants ≤ 1000 Grams

**Neil Tailor** , Leah Apalodimas, Jorden Cunningham, Le Bonheur Children's Hosp, Memphis, TN; Hitesh Agrawal, Texas Children's Hosp, Houston, TX; Benjamin Waller, Shyam Sathanandam, Le Bonheur Children's Hosp, Memphis, TN

2:40 PM

Q & A

2:45 PM

Is Norwood Shunt Type Predictive of Ventricular Arrhythmias

**Nicole Cain** , Medical Univ of SC, Charleston, SC; J Philip P Saul, West Virginia Univ, Morgantown, WV; Russell Gongwer, New England Res Insts, Watertown, MA; Anica Bulic, The Hosp for Sick Children, Toronto, ON, Canada; Richard J Czosek, Cincinnati Children's Hosp, Cincinnati, OH; Elizabeth S DeWitt, Boston Children's Hosp, Boston, MA; Allison Hill, Children's Hosp Los Angeles, Los Angeles, CA; Christopher Janson, Children's Hosp of Philadelphia, Philadelphia, PA; Jonathan Kaltman, NHLBI, Bethesda, MD; Jeffrey Kim, Texas Children's Hosp, Houston, TX; Andrew P Landstrom, Duke Univ, Durham, NC; Martin J LaPage, Univ of Michigan, Ann Arbor, MI; Mary Niu, Primary Children's Hosp, Salt Lake City, UT; Eric S Silver, Columbia Presbyterian, New York, NY; Anoop K Singh, Children's Hosp of Wisconsin, Milwaukee, WI; Deepika Thacker, AI DuPont Hosp for Children, Wilmington, DE; Felicia Trachtenberg, New England Res Insts, Watertown, MA; Robert Whitehill, Children's Healthcare of Atlanta, Atanta, GA; Jane W Newburger, Boston Children's Hosp, Boston, MA

2:50 PM

Q & A

2:55 PM

The Effect of Isoproterenol Use on Accessory Pathway Conduction Characteristics in Wolff-Parkinson-White Syndrome in Children

**Carolina Andrea Escudero** , Univ of Alberta and Stollery Children's Hosp, Edmonton, AB, Canada; Scott R Ceresnak, Stanford Univ, Palo Alto, CA; Kathryn Collins, Children's Hosp of Colorado, Aurora, CO; Robert Harrison Pass, Children's Hosp at Montefiore, Bronx, NY; Peter F Aziz, Cleveland Clinic, Cleveland, OH; Andrew Blaufox, Cohen Children's Med Ctr NY, New Hyde Park, NY; Michel Cabrera Ortega, Cardiocentro Pediátrico William Soler, La Habana, Cuba; Bryan C Cannon, Mayo Clinic, Rochester, MN; Mitchell Cohen, Inova Children's Hosp, Falls Church, VA; Brynn E Dechert-Crooks, Univ of Michigan, Ann Arbor, MI; Anne M Dubin, Standford Univ Sch Med, Palo Alto, CA; Kara Motonaga, Stanford Univ, Palo Alto, CA; Michael Richard Epstein, Maine Medical Ctr, Cape Elizabeth, ME; Christopher C Erickson, Children's Specialty Physicians/UNMC/CUMC, Omaha, NE; Steven Fishberger, Miami Children's Hosp, Miami, FL; Gregory J Gates, Children's Hosp of NY, New York, NY; Christine Capone, The Children s Hosp at Montefiore, White Plains, NY; Lynn Nappo, Montefiore Medical Ctr, Bronx, NY; Naomi J Kertesz, Nationwide Childrens Hosp, Columbus, OH; Jeffrey Kim, Texas Children's Hosp, Houston, TX; Santiago O Valdes, Texas Childrens Hosp, Houston, TX; Peter Kubus, Children's Heart Ctr, Prague, Czech Republic; Ian H Law, Univ of Iowa Childrens Hosp, Iowa City, IA; Jennifer Maldonado, Univ of Iowa Hosp and Clinics, Iowa City, IA; Jeremy Moore, UCLA Children's Health Ctr, Los Angeles, CA; James C Perry, UCSD Rady Childrens Hosp, San Diego, CA; Shubhayan Sanatani, British Columbia, Vancouver, BC, Canada; Stephen P Seslar, Seattle Childrens Hosp, Seattle, WA; Ira Shetty, Frank J Zimmerman, Advocate Childrens Hosp, Oak Lawn, IL; Jon Skinner, Starship Children's Hosp, Auckland, New Zealand; Luciana Marcondes, Starship Childrens hospital, Auckland, New Zealand; Elizabeth A Stephenson, The Hosp for Sick Children, Toronto, ON, Canada; Hiroko Asakai, Hosp for Sick Children, Toronto, ON, Canada; Ronn E Tanel, UC San Francisco, San Francisco, CA; Orhan Uzun, Univ Hosp of Wales, Cardiff, United Kingdom; Susan P Etheridge, PCOS Eccles Building, Salt Lake Cty, UT; Christopher Janson, Children's Hosp of Philadelphia, Philadelphia, PA

3:00 PM

Q & A

# Abstract Rapid Fire Oral

## EP.RFO14 - Epidemiological Approaches to Addressing the the Gender and Racial Disparities in Atrial Fibrillation

#### Science and Technology Hall A, Booth 605, Level 2

### Saturday, November 16, 2019, 2:15 PM - 3:05 PM

2:15 PM

Moderator

Sana M Al-khatib, Durham, NC

2:15 PM

Sex Differences in Atrial Fibrillation Risk: Insights From the Vital Rhythm Study

**Hasan K Siddiqi** , Manickavasagar Vinayagamoorthy, Brigham and Women's Hosp, Boston, MA; Baris Gencer, TIMI Study Group, Boston, MA; Chee Ng, Massachusetts General Hosp, Boston, MA; Julie Pester, Nancy R Cook, Brigham and Women's Hosp, Boston, MA; I-Min Lee, Julie E Buring, Joann E Manson, Harvard Medical Sch, Boston, MA; Christine M Albert, Brigham and Women's Hosp, Boston, MA

2:20 PM

Q & A

2:25 PM

Large Differences in Presentation of Atrial Fibrillation Based on Ethnicity

Benjamin Y Hsieh, Natl Yang-Ming Univ Sch of Med, Taipei, Taiwan; **David T Linker** , Univ of Washington, Seattle, WA

2:30 PM

Q & A

2:35 PM

The Influence of Race/Ethnicity on Burden of Atrial Fibrillation: The KP RHYTHM Study

Jingrong Yang, Kaiser Permanente Northern California, Oakland, CA; Kristi Reynolds, Kaiser Permanente Southern California, Pasadena, CA; Nigel Gupta, Kaiser Permanente Los Angeles Medical Ctr, Los Angeles, CA; Judith C Lenane, iRhythm Technologies, Inc., Lincolnshire, IL; Elisha Garcia, Sue Hee Sung, Kaiser Permanente Northern California, Oakland, CA; Teresa Nina Harrison, Kaiser Permanente Southern California, Pasadena, CA; Matthew Solomon, **Alan S Go** , Kaiser Permanente Northern California, Oakland, CA

2:40 PM

Q & A

2:45 PM

Risk Prediction Models for New-onset Atrial Fibrillation Among Male Workers: Usefulness of the Minnesota Code Electrocardiography Classification System

**Yu Igarashi** , Kotaro Nochioka, Murakami Tomomasa, Tokiwa Tamai, Shinya Okochi, Toshiya Irokawa, Hiromasa Ogawa, Tohoku Univ, Sendai, Japan; Hideka Hayashi, Tohoku Univ Grad Sch Med, sendai, Japan; Takahide Fujihashi, Tohoku Univ Grad Sch Med, Sendai, Japan; Shinsuke Yamanaka, Tohoku Univ Grad Sch Med, Sendai Shi, Japan; Hajime Aoyanagi, Tohoku Univ Graduate Sch, Sendai-shi Miyagi, Japan; Shintaro Kasahara, Tohoku Univ Grad Sch Med, Sendai-shi Miyagi, Japan; Takashi Shiroto, Tohoku Univ, Sendai, MA, Japan; Satoshi Miyata, Tohoku Univ, Sendai, Japan; Yasuhiko Sakata, Tohoku Univ Grad Sch Med, Sendai, Japan; Shogo Yamada, Morinomiyako Sangyohokenkai, Sendai, Japan; Hajime Kurosawa, Tohoku Univ, Sendai, Japan; Hiroaki Shimokawa, Tohoku Univ Grad Sch Med, Sendai City, Japan

2:50 PM

Q & A

2:55 PM

Race-Ethnicity Modulates Atrial Fibrillation Symptom Burden and Quality of Life

**Mary Carolina Rodriguez Ziccardi** , Maha Ahmed, Yining Chen, Vivek Mehta, Univ of Illinois at Chicago, Chicago, IL; Zain Alzahrani, Faisal Darbar, UIC, Chicago, IL; Aylin Ornelas-Loredo, Aamir Twing, Univ of Illinois at Chicago, Chicago, IL; Ahmad Musa, UIC, Chicago, IL; Baha'a Al-Azzam, Presence Saint Francis Hosp, evanston, IL; Sreenivas Konda PhD, Dawood Darbar, Univ of Illinois at Chicago, Chicago, IL

3:00 PM

Q & A

# Abstract Rapid Fire Oral

## CE.RFO2 - New Insights into Making Cardiomyocytes

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 2:15 PM - 3:05 PM

2:15 PM

Moderator

Tamer Mohamed, Louisville, KY

2:15 PM

Single-cell RNA-seq and Patient-specific IPSCs Reveal Endocardial and Endothelial Abnormalities in Hypoplastic Left Heart Syndrome

**Yifei Miao** , Stanford Sch of Med, Stanford, CA; Lei Tian, Stanford Cardiovascular Inst, Stanford, CA; Francisco Xavier Galdos, Stanford Univ, Stanford, CA; Sharon Paige, Stanford Univ, Palo Alto, CA; Marcy Martin, Ning Ma, Joseph C Wu, Stanford Univ, Stanford, CA; Timothy J Nelson, Mayo Clinic, Rochester, MN; Sean M Wu, Mingxia Gu, Stanford Univ, Stanford, CA

2:20 PM

Q & A

2:25 PM

Fzd2 Inhibits Yap and Prevents Cell-Cycle Reentry in Adult Murine Cardiomyocytes

Joseph Bisson, Pearl J Quijada, Janet Lighthouse, Eric M Small, **Ethan D Cohen** , Univ of Rochester, Rochester, NY

2:30 PM

Q & A

2:35 PM

Do Extracellular Vesicles Protect the Ischemic Myocardium Through the Proliferation of Pre-existing Cardiomyocytes?

Maria Perotto, **Bruna Lima Correa** , Nadia El Harane, Manon Desgres, Laetitia Pidial, Valérie Bellamy, INSERM U970, Paris, France; Noémie Tence, Emilie Baron, Hôpital Européen Georges Pompidou, Paris, France; Gwennhael Autret, Chloé Guillas, Keirththana Kamaleswaran, José Vilar, INSERM U970, Paris, France; Nisa Karin Elaine Renault, Fujifilm, Madison, WI; Massimiliano Gnecchi, Univ of Pavia, Pavia, Italy; Jean-Sébastien Silvestre, INSERM U970, Paris, France; Philippe Menasché, Hôpital Européen Georges Pompidou, Paris, France

2:40 PM

Q & A

2:45 PM

Mechanical Loading Regulates Cardiomyocytes Proliferation in Engineered Heart Tissues

**Giulio Ciucci** , Luca Camparini, Lorenzo Ciacci, Sara Boer, ICGEB, Trieste, Italy; Giovanni Cimmino, Paolo Golino, Univ of Campania, Naples, Italy; Gianfranco Sinagra, Univ of Trieste, Trieste, Italy; Francesco S Loffredo, Univ of Campania, Naples, Italy

2:50 PM

Q & A

2:55 PM

Mnk2 Kinase Promotes Cardiomyocyte Proliferation via Eif4e Phosphorylation in Mouse Heart After Myocardial Infarction

**Bing-Rui Chen** , Yi Fan, YaFei Li, Hao Wang, Lian-Sheng Wang, Nanjing Medical Univ, Nanjing, China

3:00 PM

Q & A

# Abstract Rapid Fire Oral

## EA.RFO10 - Strategies for Preventing Stroke in Atrial Fibrillation

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 2:15 PM - 3:05 PM

2:15 PM

Moderator

Cynthia Tracy, Washington, DC

2:15 PM

Percutaneous Implantation of Left Atrial Appendage Occlusion Devices in Younger Patients: Insights From the National Inpatient Sample

**Abdullah Sarkar** , Univ of Miami, Miami, FL; Talal Alzahrani, George Washington Univ, Washington, DC; Mikhael F El-Chami, Emory Univ, Atlanta, GA; Alexander Llanos, Jim Moran Heart and Vascular Ctr in Holy Cross Hosp, Fort Lauderdale, FL; Joseph Krepp, George Washington Univ, Washington, DC

2:20 PM

Q & A

2:25 PM

Prevalence and Predictors of Left Atrial Appendage Thrombus in Non-vitamin K Oral Anticoagulant Users With Nonvalvular Atrial Fibrillation and Flutter

**Maulin Shah** , Neigena Mobaligh, Adam Niku, Takahiro Shiota, Robert J Siegel, Florian Rader, Cedars Sinai Medical Ctr, Los Angeles, CA

2:30 PM

Q & A

2:35 PM

**Latent Risk of Cardioembolic Stroke in the Non-Paroxysmal Atrial Fibrillation Patients With CHADS** 2 **Score of 0**

**Akira Tashiro** , Yasuaki Tanaka, Atsushi Takahashi, Yokosuka Kyosai Hosp, Yokosuka, Kanagawa, Japan

2:40 PM

Q & A

2:45 PM

Comparative Outcomes of Direct Oral Anticoagulants versus Warfarin in Morbidly Obese Patients With Non-valvular Atrial Fibrillation

**Amr F Barakat** , Univ of Pittsburgh Medical Ctr, pittsburgh, PA; Sandeep Jain, Univ of Pittsburgh, Wexford, PA; Ahmad Masri, Univ of Pittsburgh, Pittsburgh, PA; Mourad Senussi, Univ of Pittsburgh Medical Ctr, pittsburgh, PA; Yisi Wang, Univ of Pittsburgh, Pittsburgh, PA; Aditya Bhonsale, Univ of Pittsburgh Medical Ctr, pittsburgh, PA; Samir Saba, UPMC, Pittsburgh, PA; Suresh Raghu Mulukutla, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA

2:50 PM

Q & A

2:55 PM

Long-term Clinical Outcomes Of Left Atrial Appendage Electrical Isolation In Patients With Non-paroxysmal Atrial Fibrillation: A Propensity Score Matching Study

Jorge Romero, Montefiore Albert Einstein, Bronx, NY; Luigi Di Biase Sr., Albert Einstein Coll of Med, New York, NY; Chintan G Trivedi, Texas Cardiac Arrhythmia Inst, Austin, TX; Sanghamitra Mohanty, St.Davids Medical Ctr, Austin, TX; Saul Rios, Montefiore Albert Einstein, Bronx, NY; **Isabella Alviz** , Montefiore Medical Ctr, Bronx, NY; Luis Cerna, Montefiore Albert Einstein, Bronx, NY; David Burkhardt, Amin Al-ahmad, Rodney Horton, Texas Cardiac Arrhythmia Inst, Austin, TX; Andrea Natale, Texas Cardiac Arrhythmia, Austin, TX

3:00 PM

Q & A

# Moderated Digital Posters

## EA.MDP5 - Arrhythmia Detection - Novel Approaches

#### Moderated Posters 2, Science and Technology Hall

### Saturday, November 16, 2019, 2:15 PM - 3:05 PM

2:15 PM

Moderator

Taya V Glotzer, Hackensack, NJ

2:15 PM

New Algorithms Reduce Clinician Review Burden and Maintain Diagnostic Yield for Repetitive ECGs in Insertable Cardiac Monitors

**Laura Van Heel** , Centracare Heart & Vascular Ctr., Saint Cloud, MN; Kevin T. Ousdigian, Medtronic, Inc, Minneapolis, MN; Amber Seiler, ConeHealth Medical Group HeartCare, Greensboro, NC; Carola Alfaro Vives, Ya-Jian Cheng, Medtronic, Mounds View, MN; John Rogers, Scripps Clinic, La Jolla, CA

2:20 PM

Q & A

2:25 PM

Skin Sympathetic Nerve Activity and the Short-Term QT Interval Variability in Patients With Electrical Storm

**Songwen Chen** , Krannert Inst of Cardiology, Indianapolis, IN; Anisiia Doytchinova, The Div of Cardiovascular Health and Disease, Cincinnati, OH; Johnson Wong, Susan Straka, Krannert Inst of Cardiology, Indianapolis, IN; Gianfranco Piccirillo, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, "La Sapienza" Univ of Rome, Rome, Italy; Thomas H. Everett, Krannert Inst of Cardiology, Indianapolis, IN; Peng-Sheng Chen, Krannert Inst Of Cardiolo, Indianapolis, IN

2:30 PM

Q & A

2:35 PM

Novel Low Cost QTc Meter for the Detection of QT Prolongation in Infants and Toddlers: A Prospective Study

**Johan Martijn Bos** , Mayo Clinic Coll of Med, Rochester, MN; Nick W Rydberg, Minnesota HealthSolutions Corp., Rochester, MN; Trena Thome, Mayo Clinic Coll of Med, Rochester, MN; Jean-Philippe Y Couderc, Uinversity of Rochester Medical Ctr, Rochester, NY; Joshua D Bowe, Melanie A Deyo, Mayo Clinic Coll of Med, Rochester, MN; Paul L Gibson, Advanced Medical Electronics Corp., Maple Grove, MN; Patrick Lichter, Koronis Biotech, Maple Grove, MN; Greg J Seifert, Advanced Medical Electronics Corp., Maple Grove, MN; Michael John Ackerman, Mayo Clinic, Rochester, MN

2:40 PM

Q & A

2:45 PM

A Novel Means to Successfully Differentiate Wide-Complex Tachycardias Using Mathematically-Synthesized Vectorcardiogram Signals

Peter Alexander Noseworthy, **Anthony Kashou** , Adam May, Christopher V Desimone, Abhishek Deshmukh, Mayo Clinic, Rochester, MN; David Hodge, Mayo Clinic, Jacksonville, FL; Rickey Carter, Mayo Clinic, Rochester, MN

2:50 PM

Q & A

2:55 PM

Predicting Atrial Fibrillation Using a Combination of Genetic Risk Score and Clinical Risk Factors

**Yousaku Okubo** , Yukiko Nakano, Hiroshima Univ, Hiroshima, Japan; Shunsuke Miyauchi, Hiroshima Univ Hosp, Hiroshima, Japan; Sho Okamura, Hiroshima Univ Hosp, Hiroshima-shi, Japan; Ikeuchi Yoshihiro, Naoya Hironobe, Hiroshima Univ, Hiroshima, Japan; Takehito Tokuyama, Yasuki Kihara, Hiroshima Univ Hosp, Hiroshima, Japan

3:00 PM

Q & A

# Moderated Digital Posters

## LF.MDP20 - Climate, Environment & Heart Disease

#### Moderated Posters 7, Science and Technology Hall

### Saturday, November 16, 2019, 2:15 PM - 3:05 PM

2:15 PM

Moderator

Michelle A Albert, San Francisco, CA

2:15 PM

Spatial Risk Factors Impact Cardiovascular Mortality: Analysis From the Golestan Cohort Study

**Michael Hadley** , Icahn Sch of Med at Mount Sinai, New York, NY; Mahdi Nalini, Tehran Univ of Medical Sciences, Tehran, Iran, Islamic Republic of; Samrachana Adhikari, Jackie Szymonifka, New York Univ Sch of Med, New York, NY; Arash Etemadi, Tehran Univ of Medical Sciences, Tehran, Iran, Islamic Republic of; Farin Kamangar, Morgan State Univ, Baltimore, MD; Masoud Khoshnia, Golestan Univ of Medical Sciences, Gorgan, Golestan, Iran, Islamic Republic of; Jesse McChane, Icahn Sch of Med at Mount Sinai, New York, NY; Akram Pourshams, Hossein Poustchi, Tehran Univ of Medical Sciences, Tehran, Iran, Islamic Republic of; Sadaf Ghajarieh Sepanlou, Tehran Univ of Medical Scienc, Tehran, Iran, Islamic Republic of; Paolo Boffetta, Icahn Sch of Med at Mount Sinai, New York, NY; Reza Malekzadeh, Tehran Univ of Medical Sciences, Tehran, Iran, Islamic Republic of; Rajesh Vedanthan, New York Univ Sch of Med, New York, NY

2:20 PM

Panel Discussion

2:25 PM

Associations Between Built Environment on Insulin Resistance and Hemoglobin A1c in a Population-Based Cohort

**Mohan Thanikachalam** , Tufts Univ Sch of Med, Boston, MA; Sadagopan Thanikachalam, Sri Ramachandra Univ, Porur, India; Kevin Lane, Boston Univ Sch of Public Health, Boston, MA

2:30 PM

Miscellaneous

2:35 PM

Association Between Long-Term Exposure to Ambient Fine Particular Matter and Blood Pressure Among Chinese Adults: Findings From China PEACE Million Persons Project

**Jiali Song** , Yan Gao, Shuang Hu, Xi Li, Jing Li, Xin Zheng, Fuwai Hosp, Beijing, China

2:40 PM

Q & A

2:45 PM

Lag Effect of Temperature and Atmospheric Pressure Affects the Incidents and the Manner of Acute Heart Failure

**Takahiro Jimba** , Masao Yamasaki, Akito Shindo, Kazunori Takemura, Youichi Iwasaki, Junya Matsuda, Yoshiya Yamamoto, Makoto Takei, Daisuke Kitano, Yasuyuki Shiraishi, Shigeto Tsukamoto, Shun Kohsaka, Yuji Nagatomo, Tetsuro Miyazaki, Kenichi Matsushita, Takamichi Miyamoto, Kiyoshi Iida, Shinji Koba, Toshiaki Otsuka, Kazumasa Harada, Takeshi Yamamoto, Ken Nagao, Morimasa Takayama, Tokyo CCU Network Scientific Committee, Tokyo, Japan

2:50 PM

Q & A

2:55 PM

Exposure to Ambient Air Pollution and Coronary Calcification

**Quan Huynh** , Prasanna Venkataraman, Baker Heart and Diabetes Inst, Melbourne, Australia; Luke Knibbs, Univ of Queensland, Brisbane, Australia; Fay Johnston, Univ of Tasmania, Hobart, Australia; Thomas H Marwick, Baker Heart and Diabetes Inst, Melbourne, Australia

3:00 PM

Q & A

# Moderated Digital Posters

## IM.MDP8 - Cutting-Edge Echocardiography: Strain and Mechanics

#### Moderated Posters 3, Science and Technology Hall

### Saturday, November 16, 2019, 2:15 PM - 3:05 PM

2:15 PM

Association Between Increased Body Mass Index and Adverse Right Ventricular Mechanics: A Community-based Cohort Study

**Koki Nakanishi** , The Univ of Tokyo, Tokyo, Japan; Masao Daimon, THE UNIVERSITY OF TOKYO HOSPITAL, Tokyo, Japan; Yuriko Yoshida, Jumpei Ishiwata, Naoko Sawada, Megumi Hirokawa, The Univ of Tokyo, Tokyo, Japan; Hidehiro Kaneko, Brandenburg Heart Ctr, Bernau bei Berlin; Tomoko Nakao, The Univ of Tokyo, Tokyo, Japan; Yoshiko Mizuno, Harvard Medical Sch, Beverly, MA; Hiroyuki Morita, The Univ of Tokyo, Tokyo, Japan; Marco Di Tullio, Columbia Presbyterian Medical Ctr, New York, NY; Shunichi HOMMA, Columbia Univ, New York, NY; Issei Komuro, The Univ of Tokyo, Tokyo, Japan

2:20 PM

Q & A

2:25 PM

Impact of Impaired Right Ventricular Strain on Prognosis in Heart Failure With Preserved Ejection Fraction

Sibille Lejeune, Cliniques Univires Saint-Luc, Brussels, Belgium; Clotilde Roy, Alisson France Slimani, Agnes A Pasquet Jr., Cliniques Univires Saint-Luc, Bruxelles, Belgium; David Vancraeynest, Cliniques Univires Saint-Luc, Brussels, Belgium; Christophe Beauloye, IREC - UCL, Brussels, Belgium; Jean-Louis Vanoverschelde, Cliniques Univires Saint-Luc, Brussels B, Belgium; Bernhard L Gerber, **Anne Catherine Pouleur** , Cliniques Univires Saint-Luc, Brussels, Belgium

2:30 PM

Q & A

2:35 PM

Relationship Between Left Ventricular Work Efficiency and Mechanical Dispersion in Patients With Heart Failure

**Marina Kostyukevich** , Leiden Univ Medical Ctr, Leiden, Netherlands; Pieter van der Bijl, Leiden Univ Medical Ctr, Leiden; Ngoc Mai Vo, Nina A Ajmone Marsan, Leiden Univ Medical Ctr, Leiden, Netherlands; Victoria Delgado, Leiden Univ Medical Ctr, Leiden; Jeroen J Bax, Leids Univ Medisch Centrum, Leiden, Netherlands

2:40 PM

Q & A

2:45 PM

Incremental Value of Left Ventricular Global Longitudinal Strain in Patients With Moderate Aortic Stenosis

**Stephan M Pio** , Leiden Univ Medical Ctr, Leiden, Netherlands; Elise Mara Vollema, Leiden Univ Medical Ctr, Leiden; Arnold Ng, Liverpool Hosp, Sydney, Australia; Nina A Ajmone Marsan, Leiden Univ Medical Ctr, Leiden, United Kingdom; Jeroen J Bax, Leids Univ Medisch Centrum, Leiden, United Kingdom; Victoria Delgado, Leiden Univ Medical Ctr, Leiden

2:50 PM

Q & A

2:55 PM

Hematopoietic Stem-Cell Transplantation Improves Right Ventricular Strain in Patients With Systemic Sclerosis

**Emily J Li** , Northwestern Univ, Chicago, IL; William Schultz, Northwestern Memorial Hosp, Chicago, IL; Stanley Swat, Univ of Colorado, Chicago, IL; Arif Jivan, Northwestern Memorial Hosp, Chicago, IL; Sanjiv J Shah, Richard Burt, Benjamin Howard Freed, Northwestern Univ, Chicago, IL

3:00 PM

Q & A

# Moderated Digital Posters

## HT.MDP23 - Machine Learning and Artificial Intelligence

#### Moderated Posters 8, Science and Technology Hall

### Saturday, November 16, 2019, 2:15 PM - 3:05 PM

2:15 PM

Implementation Of Flag, Identify, Network, Deliver: Find FH Using The Electronic Medical Record To Identify Familial Hypercholesterolemia Within A Single Healthcare System

**Samip Sheth** , Univ of Pennsylvania, Philadelphia, PA; Latoya Williamson, FH Fndn, Pasadena, CA; Jinbo Chen, Univ of Pennsylvania, Philadelphia, PA; David Staszak, FH Fndn, Pasadena, CA; Gayley Webb, Marjorie Risman, Yuliya Borovskiy, Erik Hossain, Jihane Hajj, Kady Diu, Univ of Pennsylvania, Philadelphia, PA; Julia A Larsen, Jennifer Boring, Cynthia Mays, Quest Diagnostics, Alameda, CA; William Howard, Dave Zuzick, FH Fndn, Pasadena, CA; Archna Bajaj, Daniel E Soffer, Marina Cuchel, Univ of Pennsylvania, Philadelphia, PA; Samuel Gidding, Katherine A Wilemon, FH Fndn, Pasadena, CA; Daniel J Rader, Univ of Pennsylvania, Philadelphia, PA; Kelly Myers, FH Fndn, Pasadena, CA; Douglas Jacoby, Univ of Pennsylvania, Philadelphia, PA

2:20 PM

Q & A

2:25 PM

A Novel Machine-Learning Method to Better Estimate Low-Density Lipoprotein Cholesterol Levels Using Electronic Health Records

**Gyu Chul Oh** , Tae-Hoon Ko, Hae-young Lee, Seoul Natl Univ Hosp, Seoul, Korea, Republic of

2:30 PM

Q & A

2:35 PM

Artificial Intelligence Finds Myocardial Infaction in ECG More Accurately Than Cardiologists

**Hisaki Makimoto** , Moritz Hoeckmann, Shqipe Gerguri, Lukas Clasen, Jan Schmidt, Athena Assadi-Schmidt, Alexandru Bejinariu, Patrick Mueller, David Gloeckner, Stephan Angendohr, Christoph Brinkmeyer, Malte Kelm, Medical Faculty, Univ Duesseldorf, Duesseldorf, Germany

2:40 PM

Q & A

2:45 PM

Prospective Analysis of Utility of Signals From an Ecg-Enabled Stethoscope to Automatically Detect a Low Ejection Fraction Using Neural Network Techniques Trained From the Standard 12-Lead Ecg

**Zachi I Attia** , Jennifer Dugan, Mayo Clinic, Rochester, MN; John Maidens, Eko, Berkeley, CA; Adam Rideout, Eko, Berekely, CA; Francisco Lopez-Jimenez, Peter Alexander Noseworthy, Samuel Asirvatham, Patricia A Pellikka, Dorothy J Ladewig, Gaurav Satam, Mayo Clinic, Rochester, MN; Steve Pham, Eko, Rochester, MN; Subramaniam Venkatraman, EKO HEALTH, Berkeley, CA; Paul Friedman, Suraj Kapa, Mayo Clinic, Rochester, MN

2:50 PM

Q & A

2:55 PM

Machine Learning for Risk Prediction of Future Clinical Events in Patients With Acute Coronary Syndrome Undergone Percutaneous Coronary Intervention

**Jin Sup Park** , Pusan Natl Univ Hosp, Busan, Korea, Republic of

3:00 PM

Q & A

# Moderated Digital Posters

## CE.MDP17 - No Letters, No Burning... Just the Flames of Inflammation

#### Moderated Posters 6, Science and Technology Hall

### Saturday, November 16, 2019, 2:15 PM - 3:05 PM

2:15 PM

Moderator

Shyam S Bansal, Columbus, OH

2:15 PM

Long Term Alterations in Reactivity of Circulating Monocytes After Elective Heart Surgery

Karima Rai, Maria Mukhanova, Drexel Univ, Philadelphia, PA; Da Liu, China Medical Univ Shengjing Hosp, Shenyang, China; Matthew DiMeglio, Philadelphia Coll of Osteopathic Med, Philadelphia, PA; Jihane Hajj, Widener Univ, Chetser, PA; **Krzysztof Laudanski** , Univ of Pennsylvania, Philadelphia, PA

2:20 PM

Q & A

2:25 PM

Preconditioning of Cardiosphere Derived Cells With Secretome of Apoptotic Peripheral Blood Mononuclear Cells Enhances Cardiac Repair Efficacy

**Mariann Gyongyosi** , Medical Univ of Vienna, Vienna, Austria; Dominika Lukovic, Medical Univ of Vienna, Vienna; Julia Mester-Tonczar, Katrin Zlabinger, Alfred Gugerell, Medical Univ of Vienna, Vienna, Austria; Noemi Pavo, Medical Univ of Vienna, Vienna; Andras Jakab, Zsuzsanna Szankai, Denise Traxler, Claudia Müller, Andreas Spannbauer, Medical Univ of Vienna, Vienna, Austria; Martin Riesenhuber, Medical Univ of Vienna, Vienna; Ena Hasimbegovic, Medical Univ of Vienna, Vienna, Austria; James Frederick Dawkins, Cedars-Sinai Medical Ctr, W Hollywood, CA; Hendrik Jan Ankersmit, Medical Univ of Vienna, Vienna, Austria; Eduardo Marban, Cedars-Sinai Medical Ctr, Los Angeles, CA; Johannes Winkler, Medical Univ of Vienna, Vienna, Austria

2:30 PM

Q & A

2:35 PM

miR-146a-5p Mimic Induces Inflammation in the Heart via Toll-Like Receptor 7

**Briana K Shimada** , Se-Chan Kim, Univ of Maryland, Baltimore, Baltimore, MD; Yang Yang, Univ of Maryland Sch of Med, Baltimore, Baltimore, MD; Lin Zou, Univ of Maryland Sch of Me, Baltimore, MD; Wei Chao, Univ of Maryland Sch of Med, Baltimore, MD

2:40 PM

Q & A

2:45 PM

A New Vagal Stimulation Technique to Activate Neuromodulation of Splenic Immune Response: Physiopathological Mechanisms in Experimental Models of Hypertension

**Lorenzo Carnevale** , I.R.C.C.S. Neuromed, Pozzilli, Italy; Marialuisa Perrotta, IRCCS Neuromed, Pozzilli, Italy; Fabio Pallante, I.R.C.C.S. Neuromed, Pozzilli, Italy; Daniela Carnevale, Sapien Univ/I.R.C.C.S. Neuromed, Pozzilli, Italy; Giuseppe Lembo, IRCCS Neuromed, Pozzilli, Italy

2:50 PM

Q & A

3:00 PM

Q & A

# Moderated Digital Posters

## DD.MDP11 - On the Road to Translation: Moving Beyond Rodents

#### Moderated Posters 4, Science and Technology Hall

### Saturday, November 16, 2019, 2:15 PM - 3:05 PM

2:15 PM

Humoral Cardioprotective Factors are Released by Remote Ischemic Perconditioning in Pigs and Reduce Infarct Size When Given Before or After Ischemia in Isolated Perfused Rat Hearts

Helmut Raphael Lieder, Andreas Skyschally, Gerd Heusch, **Petra Kleinbongard** , Univsklinikum Essen, Essen, Germany

2:20 PM

Q & A

2:25 PM

**Chronic Treatment With a Mavacamten-Like Myosin-Modulator (MYK-581) Blunts Disease Progression in a Mini-Pig Genetic Model of Non-Obstructed Hypertrophic Cardiomyopathy:** In Vivo **Evidence for Improved Relaxation and Functional Reserve**

**Carlos L del Rio** , Aprajita Yadav, Brian S Ferguson, Christopher Zambataro, MyoKardia, San Francisco, CA; Trisha Smit, Frank Rohret, John Swart, Exemplar Genetics, Sioux Center, IA; Lee-Jae Guo, Allison Hargraves, Julie Grinde, Vidya Sridhar, Texas A&M Univ, College Station, TX

2:30 PM

Q & A

2:35 PM

5-lipoxygenase Pathway Inhibition Improved Cardiac Function in an Aged Primate Model of Human Cardio-Metabolic Disease

**Johannes Wikstrom** , AstraZeneca, Gothenburg, Sweden; Yongqiang Liu, Crown Bioscience, Taicang, China; Carl Whatling, Elyse DiMarco, Carl Amilon, Luna Prieto Garcia, Peter Konings, Jan Olsson, AstraZeneca, Gothenburg, Sweden; Yanqin Ji, Yongfu Xiao, Crown Bioscience, Taicang, China; Stanko Skrtic, Peter Greasley, Eva-Lotte Lindstedt Alstermark, AstraZeneca, Gothenburg, Sweden; Yixin Wang, Crown Bioscience, Taicang, China; Li-Ming Gan, AstraZeneca, Goteborg, Sweden

2:40 PM

Q & A

2:45 PM

A Severe Sustained Decrease in Left Heart Flow Results in Left Ventricular Hypoplasia in Mid-Gestation Fetal Lambs

**Rajiv R Chaturvedi** , The Hosp for Sick Children, Toronto, ON, Canada; Johannes Keunen, Mount Sinai Hosp, Toronto, ON, Canada; Barbra de Vrijer, London Health Sciences Ctr, London, ON, Canada; Greg Ryan, Mount Sinai Hosp, Toronto, ON, Canada; Edgar T Jaeggi, The Hosp for Sick Children, Toronto, ON, Canada

2:50 PM

Q & A

2:55 PM

Diastolic Dysfunction Accompanies Myocardial Structural And Cellular Alterations In Rhesus Macaque Survivors Of Ionizing Radiation Exposure

**Thomas C Register** , Wake Forest Sch of Med, Winston Salem, NC; Kristofer T Michalson, Wake Forest Sch of Med, Winston-Salem, NC; Dalane W Kitzman, Wake Forest Baptist Health, Winston Salem, NC; Greg Dugan, David Caudell, Wake Forest Sch of Med, Winston Salem, NC; J Mark Cline, Wake Forest Sch of Med, Winston-Salem, NC

3:00 PM

Q & A

# Moderated Digital Posters

## AT.MDP14 - Regulation of Vascular Inflammation and Aneurysm

#### Moderated Posters 5, Science and Technology Hall

### Saturday, November 16, 2019, 2:15 PM - 3:05 PM

2:15 PM

Endothelial-Specific Deficiency of Thrombospondin-1 Attenuates Abdominal Aortic Aneurysm Through Modulating Vascular Remodeling

Ting Zhou, **Carmel Assa** , Amelia Stranz, Binkai Liu, Huan Yang, Christine M Sorenson, Nader Sheibani, Bo Liu, Univ of Wisconsin-Madison, Madison, WI

2:20 PM

Q & A

2:25 PM

Xanthine Oxidoreductase in Adventitial Macrophages Amplifies Reactive Oxygen Generation and Aggravates Aortic Aneurysm Progression in a Mouse Model of Marfan Syndrome

**Hiroki Yagi** , The Univ of Tokyo Hosp, Tokyo, Japan; Hiroshi Akazawa, Univ Tokyo, Tokyo, Japan; Qing Liu, Akiko Saga-Kamo, Chizuru Yabumoto, Masahiko Umei, Hiroshi Matsunaga, Hiroshi Kadowaki, Ryo Matsuoka, The Univ of Tokyo Hosp, Tokyo, Japan; Norifumi Takeda, Issei Komuro, Univ of Tokyo, Tokyo, Japan

2:30 PM

Q & A

2:35 PM

Uncoupling of Endothelial No Synthase Mediates Thoracic Aortic Aneurysm Formation in Fbn1 Marfan Syndrom Mice: Therapeutic Effects of Folic Acid and TGFβ Antagonism via Attenuation of Nox4

**Kai Huang** , Yongchen Wang, Kin Lung Siu, Yixuan Zhang, Hua Linda Cai, UCLA, Los Angeles, CA

2:40 PM

Q & A

2:45 PM

EP4 Signaling in Smooth Muscle Cells Causes Abdominal Aortic Aneurysm by Attraction of Immune Infiltrates

**Taro Hiromi** , Yokohama City Univ Graduate Sch of Med, Yokohama, Japan; Utako Yokoyama, Tokyo Medical Univ, Tokyo, Japan; Ichiro Takeuchi, Yoshihiro Ishikawa, Yokohama City Univ Graduate Sch of Med, Yokohama, Japan

2:50 PM

Q & A

2:55 PM

Inducible Deficiency of Notch1 in Myeloid Cells Attenuates Angiotensin Ii-Induced Abdominal Aortic Aneurysm

**Chetan P Hans** , Neekun Sharma, Univ of Missouri, Columbia, MO

3:00 PM

Q & A

# Moderated Digital Posters

## AC.MDP2 - Uncommon Causes of Cardiovascular Morbidity

#### Moderated Posters 1, Science and Technology Hall

### Saturday, November 16, 2019, 2:15 PM - 3:05 PM

2:15 PM

Moderator

sukhdeep s Basra, Houston, TX

2:15 PM

Failure of Left Cardiac Sympathetic Denervation in Pregnancy in a Patient With Catecholaminergic Polymorphic Ventricular Tachycardia

**Danni Fu** , Neal Dharmadhikari, Lifespan - Brown Univ, Providence, RI; Athena Poppas, Rhode Island Hosp, Providence, RI; Philip Stockwell, Brown Univ Sch of Med, East Providence, RI; Angie Seo, Lifespan - Brown Univ, Providence, RI

2:20 PM

Q & A

2:25 PM

A Deadly Sting: Recognizing Kounis Syndrome, a Rare Cause of Myocardial Infarction

**Jugeet Kanwal** , Crozer Chester Medical Ctr, upland, PA; Janet Fontanella, Jonathan Finkel, Crozer Chester Medical Ctr, Upland, PA

2:30 PM

Q & A

2:35 PM

Biventricular Takotsubo Cardiomyopathy as the Initial Manifestation of a Pheochromocytoma

**Azucena Martinez Caballero** , Sebastian Gallo-Bernal, Fundacion Cardioinfantil, Bogota, Colombia; Nicolas Isaza, Fundacion Cardioinfantil- Cardiology Inst, Bogota, Colombia; Daniel Isaza, Fundacion Cardioinfantil - Insto de Cardiologua, Bogota, Colombia; Claudia Jaimes, Fundacion Cardioinfantil, Bogota, Colombia

2:40 PM

Q & A

2:45 PM

New Intervention Therapy Of Acute Renal Infarction Caused By Atrial Fibrillation: A Case Report

**Tao Ge** , Jinfeng Wang, ZhengCai Zhu, Wenjiao Zhou, Bi-Hua Tan, Shengxing Tang, The First Affiliated Hosp, Wan Nan Medical Coll, Wuhu, China

2:50 PM

Q & A

2:55 PM

Takotsubo Cardiomyopathy: Experience in a Latin-American Center

**Juan F Vasquez** , Azucena Martinez Caballero, Oscar Pérez-Fernandez, Sergio Higuera, Fundacion Cardioinfantil, Bogota, Colombia; Julian Gelves, Fundacion Cardioinfantil- Cardiology Inst, Bogota, Colombia; Sebastian Gallo-Bernal, Fundacion Cardioinfantil, Bogota, Colombia; Nicolas Isaza, Daniel Isaza, Fundacion Cardioinfantil- Cardiology Inst, Bogota, Colombia; Claudia Jaimes, Fundacion Cardioinfantil, Bogota, Colombia

3:00 PM

Q & A

# FIT Event

## FIT.04 - Meet the AHA Leadership

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Saturday, November 16, 2019, 2:30 PM - 3:00 PM

This is not a CME/CE certified session

# Hall

## CS.HT.103 - Reproducibility, Rigor & Transparency Initiatives at the AHA Journals

#### Heart Theater

### Saturday, November 16, 2019, 2:30 PM - 3:30 PM

2:30 PM

Moderator

N A Estes III, Pittsburgh, PA

2:30 PM

Introduction

N A Estes III, Pittsburgh, PA

2:35 PM

**Rigor and Reproducibility Initiatives: A Case Study at** ATVB

Alan Daugherty, Lexington, KY

2:45 PM

**Strengthening Figure Requirements: A Case Study at** Circulation Research

Jane E Freedman, Worcester, MA

2:55 PM

**Data and Statistical Code Sharing: A Case Study at** Circulation: Cardiovascular Quality and Outcomes

Brahmajee Kartik Nallamothu, Ann Arbor, MI

3:05 PM

Panel Discussion featuring AHA Journal Editors

# FIT Event

## FIT.10 - FInding Your Ikigai: Maintaining Balance & Sense of Self During Training

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Saturday, November 16, 2019, 3:00 PM - 3:45 PM

This is not a CME/CE certified session

# Hall

## HT.03 - How Can the Electronic Health Record Improve Health Care?

#### Health Innovation Pavilion, Heart Hub, Science and Technology Hall, Level 2

### Saturday, November 16, 2019, 3:00 PM - 4:00 PM

3:00 PM

Moderator

David P Kao, Aurora, CO

3:20 PM

Patient-Reported Outcomes and Automated Data

John Spertus, Kansas City, MO

3:30 PM

Communicating across different EHRs: the Personal health record

Harlan M Krumholz, New Haven, CT

# Abstract Rapid Fire Oral

## HF.RFO11 - Best Heart Failure Abstracts: Pathophysiology

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 3:15 PM - 4:05 PM

3:15 PM

Moderator

Gregory Lewis, Boston, MA

3:15 PM

Pathophysiological Insights on Intrarenal Venous Flow and Right Ventricle-Pulmonary Circulation Uncoupling in Acute Heart Failure

Valentina Labate, Alessandro Vella, Gianmarco Carenini, **Maurizio Losito** , Maria Michela Caracciolo, Marina Rovida, Francesco Bandera, Marco Guazzi, IRCCS Policlinico San Donato, San Donato, Italy

3:20 PM

Q & A

3:25 PM

**Central Role of Left Atrial Dynamics in Limiting the Cardiac Output Increase and O** 2 **Uptake During Exercise in Patients With Heart Failure**

**Tadafumi Sugimoto** , MIE Univ, Tsu, Japan; Francesco Bandera, IRCCS Policlinico San Donato, Varese, Italy; Greta Generati, IRCCS Policlinico San Donato, San Donato Milanese, Italy; Eleonora Alfonzetti, Univ of Milano, Milano, Italy; Marta Barletta, IRCCS, Policlinico San Donato, San Donato Milanese, Italy; Marco Guazzi, IRCCS Policlinico San Donato, Milano, Italy

3:30 PM

Q & A

3:35 PM

Brain Angiotensin II Type 1 Receptor-Induced Disruption of Glymphatic System Increased Sympathetic Nerve Activity in Ischemic Heart Failure

**Takuya Kishi** , Int. Univ. of Health and Welfare, Okawa, Japan

3:40 PM

Q & A

3:45 PM

Importance of Early Initiation of Anti-Tumor Necrosis Factor-a With Etanercept for Slowing the Progression of Heart Failure: Insights into the Underlying Cellular and Molecular Mechanisms

**Xiaowei Zhang** , Che Ping Cheng, Tiankai Li, Zhe Chen, Yixi Liu, Peng Zhou, Heng-Jie Cheng, Wake Forest Sch of Med, Winston-Salem, NC

3:50 PM

Q & A

3:55 PM

Natriuretic Peptide Receptor C as a Therapeutic Target in Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction

**Vineet Agrawal** , Fubiao Shi, Niki L Fortune, Julio L Fuentes, David S Nichols, Linda Gleaves, Emily A Hornsby, Vanderbilt Univ Medical Cente, Nashville, TN; Evan Brittain, Vanderbilt Univ, Nashville, TN; Sheila Collins, James D West, Vanderbilt Univ Medical Ctr, Nashville, TN; Anna R Hemnes, Vanderbilt Univ, Nashville, TN

4:00 PM

Q & A

# Abstract Rapid Fire Oral

## CH.RFO7 - Cardiac and NonCardiac Consequences in Adults with Congenital Heart Disease

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 3:15 PM - 4:05 PM

3:15 PM

Ventricular Pacing for Heart Block Adversely Affects Biventricular Function in Patients With Transposition of Great Arteries

**Chieh Ju Chao** , Xuanyi Jin, Marlene Girardo, Afsoon Fazlinezhad, Mayo Clinic Arizona, Phoenix, AZ; Alexander C Egbe, Mayo Clinic, Rochester, MN; Heidi Connolly, Mayo Clinic Rochester, Rochester, MN; Tasneem Z Naqvi, Mayo Clinic Arizona, Phoenix, AZ

3:20 PM

Q & A

3:25 PM

Prognostic Value of Von Willebrand Factor in Adult Patients With Congenial Heart Disease

**Hideo Ohuchi** , Natl Cerebral and CV Ctr, Suita, Japan; Toru Iwasa, Natl Cerebral and Cardiovascular Cenetr, Suita, Japan; Heima S Sakaguchi, Natl Cerebral and Cardiovascula, Suita Osaka, Japan; Isao Shiraishi, Natl Cardiovascular Ctr, Suita, Japan

3:30 PM

Q & A

3:35 PM

Reduced Bone Mechanical Strength in Adults With Congenital Heart Disease

**Karna Johansson** , Umeå Univ, Umeå, Sweden; Camilla Sandberg, Västerbottens Läns Landsting, Umea, Sweden; Bengt Johansson, Västerbottens Läns Landsting, Umeå, Sweden

3:40 PM

Q & A

3:50 PM

Q & A

3:55 PM

Pathophysiologic and Prognostic Implications of Right Atrial Hypertension in Adults With Tetralogy of Fallot

**Alexander C Egbe** , Mayo Clinic, Rochester, MN

4:00 PM

Q & A

# Abstract Rapid Fire Oral

## AT.RFO3 - Developing Cellular Therapies

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 3:15 PM - 4:10 PM

3:15 PM

**Crosstalk Between Human IPSC-derived Lung Progenitors and Endothelial Cells Model Development of a** De Novo **Air-blood Barrier**

**Miriel Ho** , Mirabelle S.H. Ho, Duncan J Stewart, Ottawa Hosp Res Inst, Ottawa, ON, Canada

3:20 PM

Q & A

3:30 PM

Q & A

3:35 PM

Clinical Trial of Autologous CD34 Cell Therapy for Treatment of Coronary Microvascular Dysfunction in Patients With Angina and Non-Obstructive Coronary Arteries

**Noel N Merz** , Cedars- Sinai Medical Ctr, Los Angeles, CA; Timothy D Henry, The Christ Hosp, Cincinnati, OH; Janet Wei, Cedars- Sinai Medical Ctr, Los Angeles, CA; Michel Corban, Mayo Clinic, Rochester, MN; Sandy Joung, Cedars Sinai Medical Ctr, Los Angeles, CA; Christine Kotynski, Caladrius Biosciences, Rye Brook, NY; Michelle Lewis, Ann Schumacher, Ronnda Bartel, William K Sietsema, Caladrius Biosciences, Basking Ridge, NJ; Douglas W Losordo, Caladrius Biosciences, Rye Brook, NY; Amir Lerman, Mayo Clinic, Rochester, MN

3:40 PM

Q & A

3:45 PM

C1q/Tumor Necrosis Factor-Related Protein 9 Stimulates Revascularization in Response to Ischemia Through an Endothelial Nitric Oxide Synthase-Dependent Pathway

**Shukuro Yamaguchi** , Rei Shibata, Nagoya Univ, Nagoya, Japan; Koji Ohashi, Nagoya Univ, Aichi, Japan; Toyoaki Murohara, Cardiology, Nagoya Univ, Nagoya, Japan; Noriyuki Ouchi, Nagoya Univ, Nagoya, Japan

3:50 PM

Q & A

4:00 PM

Endothelial TRPV4 Deletion Protects Myocardium Against Pressure Overload Induced Hypertrophy via Preserved Angiogenesis and Reduced Cardiac Fibrosis

Ravi Adapala, **Anantha Koteswararao Kanugula** , Vahagn A Ohanyan, Northeast Ohio Medical Univ, Rootstown, OH; Sailaja M Paruchuri, Univ of Akron, Akron, OH; William M Chilian, Charles K Thodeti, Northeast Ohio Medical Univ, Rootstown, OH

4:05 PM

Q & A

# Abstract Rapid Fire Oral

## EP.RFO15 - Novel Approaches to Cardiovascular Epidemiology: The Rise of the Machines

#### Science and Technology Hall A, Booth 605, Level 2

### Saturday, November 16, 2019, 3:15 PM - 4:05 PM

3:15 PM

Moderator

Rohan Khera, Dallas, TX

3:15 PM

A Deep Learning Based Model for Risk Stratification of Sudden Cardiac Death in Hypertrophic Cardiomyopathy

**Ahmed S Fahmy** , BIDMC-Harvard Univ, Brookline, MA; Ethan J Rowin, Tufts Medical Ctr, Boston, MA; Warren J Manning, Beth Israel Deaconess Med Ctr, Boston, MA; Martin S Maron, Tufts Medical Ctr, Boston, MA; Reza Nezafat, Beth Israel Deaconess Medical Ctr, Boston, MA

3:20 PM

Q & A

3:25 PM

Machine Learning Does Not Improve Upon Traditional Regression in Predicting Outcomes in Atrial Fibrillation: An Analysis of the ORBIT-AF and GARFIELD-AF Registries

**Zak Loring** , Duke Univ Medical Ctr, Durham, NC; Suchit Mehrotra, North Carolina State Univ, Raleigh, NC; Jonathan P Piccini, Duke Univ Medical Ctr, Durham, NC; John Camm, St. George's Univ of London, London, United Kingdom; David Carlson, Duke Univ, Durham, NC; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; Keith A Fox, Cardiovasc Res, Nethy Bridge, United Kingdom; Eric D Peterson, Duke Clinical Res Institu, Chapel Hill, NC; Karen S Pieper, Duke Clinical Res Inst, Durham, NC; Ajay Kumar kakkar, Thrombosis Res Inst, London

3:30 PM

Q & A

3:35 PM

Comparing a Novel Machine Learning Method to the Martin-Hopkins Equation for Low-Density Lipoprotein Cholesterol Estimation for Levels Below 70 Mg/dl

**Yasin Hussain** , Gupreet Singh, Zhuoran Xu, Evan Sholle, Kelly Michalak, Weill Cornell Med, New York City, NY; Kristina Dolan, Weill Cornell Med, New York, NY; Gabriel Maliakal, Mohit Pandey, Benjamin Lee, Alexander van Rosendael, Lohendran Baskaran, Weill Cornell Med, New York City, NY; James K Min, Weill Cornell Med, New York, NY; Leslee Shaw, Weill Cornell Med, New York City, NY; Subhi Alaref, Weill Cornell Med, New York, NY

3:40 PM

Q & A

3:45 PM

Validation of a Deep Learning-Enabled Electrocardiogram Algorithm to Detect and Predict Cardiac Contractile Dysfunction in the Community

**Jose R Medina-Inojosa** , Itzhak Zachi Attia, Suraj Kapa, Peter Alexander Noseworthy, Paul M McKie, Mayo Clinic, Rochester, MN; Patricia A Pellikka, Mayo Clinic Coll Med, Rochester, MN; Richard J Rodeheffer, Paul Friedman, MAYO CLINIC, Rochester, MN; Francisco Lopez-jimenez, Mayo Clinic Coll Med, Rochester, MN

3:50 PM

Q & A

3:55 PM

Predicting Cardiovascular Health Trajectories in Time-series Electronic Health Records With Deep Learning

**Aixia Guo** , Olivette, MO; Randi E Foraker, Washington Univ in St. Louis, St Louis, MO

4:00 PM

Q & A

# Council Sponsored Activities

## CSA.09 - CVSN Meet and Greet

#### Pennsylvania Convention Center; room 118C

### Saturday, November 16, 2019, 3:15 PM - 3:45 PM

This is not a CME/CE certified session

# Expert Theater

## ET.07 - AstraZeneca Pharmaceuticals

#### Learning Studio 1, Booth # 5

### Saturday, November 16, 2019, 3:15 PM - 4:00 PM

This is not a CME/CE certified session

# Expert Theater

## ET.08 - Penn Medicine

#### Learning Studio 2, Booth # 7

### Saturday, November 16, 2019, 3:15 PM - 4:00 PM

This is not a CME/CE certified session

# Women's Professional Development

## WPD.02 - Volunteerism to Advance Your Career with Stacy Rosen, MD, FAHA & Michelle Albert, MD, MPH, FAHA

#### Go Red Women in Science & Medicine Lounge, Pennsylvania Convention Center, 2nd Floor, Heart Hub

### Saturday, November 16, 2019, 3:30 PM - 4:30 PM

This is not a CME/CE certified session

# Abstract Oral Session

## AT.AOS.463 - Elaine W. Raines Early Career Investigator Award

#### 126A

### Saturday, November 16, 2019, 3:45 PM - 4:45 PM

3:45 PM

Moderator

Cynthia St Hilaire, Pittsburgh, PA

3:45 PM

Moderator

Thomas A Vallim, Los Angeles, CA

3:45 PM

Orphan Receptor GPR146 Deficiency Reduces Plasma Cholesterol Levels and Protects Against Atherosclerosis

**Haojie Yu** , BIDMC at Harvard Medical Sch, Boston, MA; Antoine Rimbert, Univ of Groningen, Groningen, Netherlands; Alice Palmer, Takafumi Toyohara, BIDMC at Harvard Medical Sch, Boston, MA; Yulei Xia, Fang Xia, Leonardo Ferreira, Tao Chen, Harvard Univ, Cambridge, MA; Michael Kacergis, Liping Zhao, Alexander Soukas, Massachusetts General Hosp, Boston, MA; Jan Albert Kuivenhoven, Univ of Groningen, Groningen, Netherlands; Sekar Kathiresan, Massachusetts General Hosp, Boston, MA; Chad Cowan, Harvard Univ, Boston, MA

3:55 PM

Q & A

4:00 PM

A Naive CD8 T Cell Expressing CD95 Intensifies Cardiovascular Disease and Atherosclerosis

**Lindsey E. Padgett** , Huy Q. Dinh, La Jolla Inst for Immunology, La Jolla, CA; Dalia Gaddis, Holger Winkels, LJI, La Jolla, CA; Anh Ngyuen, Univ of Virgina, Charlottesville, VA; Coleen A McNamara, Univ Virginia, Charlottesville, VA; Catherine Hedrick, Univ Virginia, Charlottesville, VA, La Jolla, CA

4:10 PM

Q & A

4:15 PM

**Mutation in** CELA2A **Derives Early-onset Cardiovascular Diseases**

**Sahar Esteghamat** , J S Broughton, E Smith, Rebecca Cardone, T Tyagi, Mateus Guerra, Yale Sch of Med, New Haven, CT; A Szabó, Boston Univ Henry M. Goldman Sch of Dental Med, Boston, MA; N Ugwu, Yale Sch of Med, New Haven, CT; M V Mani, Yale Sch of Medical, New Haven, CT; B Azari, G Kayingo, S Chung, Jeffery Bender, S Mane, Yale Sch of Med, New Haven, CT; Rick P Lifton, The Rockefeller Univ, New York, NY; A Adeniran, M H Nathanson, F S Gorelick, John Hwa, Yale Sch of Med, New Haven, CT; M Sahin-Tóth, Boston Univ Henry M. Goldman Sch of Dental Med, Boston, MA; R Belfort-DeAguiar, Richard G Kibbey, Arya Mani, Yale Sch of Med, New Haven, CT

4:25 PM

Q & A

4:30 PM

Vascular Insulin Resistance in Patients With Cardiovascular Disease Reversed by Dpp4 Inhibition: Implications for Insulin Treatment in Diabetes

**Ioannis Akoumianakis** , Gillian Douglas, Univ of Oxford, Oxford, United Kingdom; Surawee Chuaiphichai, Oxford Univ, oxford; Laura Herdman, Marios Margaritis, Univ of Oxford, Oxford, United Kingdom; Alexios Antonopoulos, Evangelos Oikonomou, Univ of Oxford, Oxford; Rana Sayeed, Oxford Univ Hosp NHS foundation trust, Oxford, United Kingdom; George Krasopoulos, Mario Petrou, Oxford Univ hospitals NHS foundation trust, Oxford, United Kingdom; Paulus Wohlfart, Sanofi Aventis Pharma Deutschland, Frankfurt, Germany; Norbert Tennagels, Sanofi Aventis Deutschland GmbH, Frankfurt, Germany; Keith Channon, Univ of Oxford, Oxford; Charalambos Antoniades, Univ of Oxford, Oxford, United Kingdom

4:40 PM

Q & A

# Abstract Oral Session

## NR.AOS.351 - Katharine A. Lembright Award/Lecture and Martha N. Hill Early Career Investigator Award Competition

#### 118C

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Kathryn A Wood, Atlanta, GA

3:45 PM

Moderator

Cynthia M Dougherty, Seattle, WA

3:45 PM

Katharine A. Lembright Award/Lecture

Terry A Lennie, Lexington, KY

4:10 PM

Q & A

4:15 PM

Thriving in the Face of Uncertainty: Life Experiences of Adolescents With Single Ventricle Heart Disease

**Jennifer K Peterson** , Ellen F Olshansky, Yuqing Guo, Lorraine S Evangelista, Univ of California Irvine, Irvine, CA; Nancy A Pike, UCLA Sch of Nursing, Los Angeles, CA

4:25 PM

Q&A

4:30 PM

Mindfulness and Lifestyle Medicine Lowers Blood Pressure in Hypertension

**Eunjoo An** , Mary-Lynn Brecht, Lynn V. Doering, Michael R. Irwin, Karol E. Watson, Paul M. Macey, UCLA, Los Angeles, CA

4:40 PM

Q & A

4:45 PM

TAS2R38 Haplotype Predicts Vegetable Consumption in Community Dwelling Adults at Risk for Cardiovascular Disease

**Jennifer L. Smith** , Steve Estus, Terry A Lennie, Debra K Moser, Univ of Kentucky, Lexington, KY; Misook Lee Lee Chung, Univ of Kentucky Collge of Nur, Lexington, KY; Gia Mudd-Martin, Univ of Kentucky, Lexington, KY

4:55 PM

Q & A

# Abstract Oral Session

## CA.AOS.531 - Louis N. and Arnold M. Katz Basic Science Research Prize for Early Career Investigators Competition

#### 113BC

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Maha Abdellatif, Newark, NJ

3:45 PM

Moderator

Sumanth D Prabhu, Birmingham, AL

3:45 PM

MICAL1 Constrains Cardiac Stress Responses and Protects Against Disease by Oxidizing CaMKII

**Klitos Konstantinidis** , Johns Hopkins Univ, Baltimore, MD; Vassilios J Bezzerides, Boston Children's Hosp, Boston, MA; Lo Lai, NHLBI, Bethesda, MD; Holly Isbell, Univ of Iowa, Iowa City, IA; An-Chi Wei, Natl Taiwan Univ, Ellicott City, MD; Yuejin Wu, Meera Viswanathan, Ian Blum, Jonathan Granger, Johns Hopkins Univ, Baltimore, MD; Donghui Zhang, Hubei Univ, Wuhan, China; Danielle Heims-Waldron, Boston Children's Hosp, Boston, MA; Elizabeth Luczak, Johns Hopkins Univ, Baltimore, MD; Kevin R Murphy, Johns Hopkins Medical Inst, Baltimore, MD; Daniel Gratz, Ohio State Univ, Columbus, OH; Bruno Manta, Brigham and Women's Hosp, Boston, MA; Qiang Wang, Zhongshan Hosp, Fudan Univ, Shanghai, China, China; Qinchuan Wang, Johns Hopkins Univ, Balitmore, MD; Alex Kolodkin, Johns Hopkins Univ, Baltimore, MD; Vadim Gladyshev, Brigham and Women's Hosp, Boston, MA; Thomas J Hund, The Ohio State Univ, Columbus, OH; William T Pu, Boston Children s Hosp, Boston, MA; Mark Wu, Anthony Cammarato, Mario Bianchet, Johns Hopkins Univ, Baltimore, MD; Madeline Shea, Univ of Iowa, Iowa City, IA; Rodney Levine, NHLBI, Bethesda, MD; Mark E Anderson, Johns Hopkins Univ, Baltimore, MD

3:55 PM

Q & A

4:00 PM

Inhibition of mTOR Signaling Enhances Maturation of Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

**Jessica C Garbern** , Boston Children's Hosp, Boston, MA; Rebecca Sereda, Mohsen Sarikhani, Aishah Ahmed, Gabriela O Escalante, Aharon Helman, Douglas A. Melton, Richard T Lee, Harvard Univ, Cambridge, MA

4:10 PM

Q & A

4:15 PM

Abnormalities of Cardiomyocyte Polarity Underlie a Primary Genetic Substrate for Atrial Fibrillation

**Zaniar Ghazizadeh** , Brigham and Women's Hosp, Harvard Medical Sch, Boston, MA; Tuomas O Kiviniemi, Turku Univ Hosp, Turku, Finland; Soley Olafsson, David Plotnick, Brigham and Women's Hosp, Harvard Medical Sch, Boston, MA; Manu Beerens, BWH - Harvard Medical Sch, Boston, MA; Kun Zhang, Leah Gillon, Brigham and Women's Hosp, Harvard Medical Sch, Boston, MA; Michael Steinbaugh, Victor Barrera, Shannan Ho Sui, Harvard Medical Sch, Boston, MA; Andreas A Werdich, Brigham and Women's Hosp, Boston, MA; Sunil Kapur, Brigham and Women's Hosp, Harvard Medical Sch, Boston, MA; Antti Eranti, Brigham and Women's Hosp, Harvard Medical Sch, Boston, MA, Kauniainen, Finland; Jarmo Gunn, Juho Markku Jalkanen, Turku Univ Hosp, Turku, Finland; Juhani Airaksinen, Turku Univ Hosp, Washington, DC; Andre G Kleber, Beth Israel Medical Ctr, Boston, MA; Maija Hollmén, Calum MacRae, Univ of Turku, Turku, Finland

4:25 PM

Q & A

4:30 PM

Genomic Binding Patterns of Forkhead Box Protein O1 Reveal Its Unique Role in Cardiac Hypertrophy

**Jessica Pfleger** , Jessica Ibetti, Rajika Roy, Temple Univ, Philadelphia, PA; Erhe Gao, Lewis Katz Sch of Med at Temple Uni, Philadelphia, PA; Walter J Koch, Temple Univ Sch Medic, Philadelphia, PA

4:40 PM

Q & A

4:45 PM

IP3 Receptors are Master Regulators of Cardiac Healing in Post-Ischemic Heart Failure

**Gaetano Santulli** , Albert Einstein Coll of Med, New York, NY; Marco B. Morelli, AECOM, Bronx, NY; Alessandro Matarese, Colli Hosp, Naples, Italy; Xujun Wang, Albert Einstein Coll of Med, New York, NY

4:55 PM

Q & A

# Abstract Oral Session

## PR.AOS.585 - Prevention Health and Wellness

#### 204C

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Christie M Ballantyne, Houston, TX

3:45 PM

Moderator

Amit Khera, Dallas, TX

3:45 PM

Impaired Myocardial Functional Reserve Underlies Reduced Exercise Capacity and Subsequent Heart Rate Recovery in Young Adults Born Preterm

**Holger Burchert** , Odaro John Huckstep, Wilby Williamson, Fernando Telles, Univ of Oxford, Oxford, United Kingdom; Mariane Bertagnolli, Hôpital du Sacré-Coeur de Montréal Res Ctr, Montréal, QC, Canada; Linda Arnold, Afifah Mohamed, Kenny McCormick, Paul Leeson, Adam James Lewandowski, Univ of Oxford, Oxford, United Kingdom

3:55 PM

Q & A

4:00 PM

Marked Decline in Exercise Performance for Adolescents With Fontan Physiology - An Analysis of the Pediatric Heart Network Fontan Public Data Set

Jamie N Colombo, Alyssa Bernardi, Jennifer Andrews, Scott E Klewer, **Michael D Seckeler** , Univ of Arizona, Tucson, AZ

4:10 PM

Q & A

4:15 PM

Improvement in Maximal Exercise Capacity is Inversely Related to Incident Ischemic Stroke: Data From the Henry Ford Exercise Testing (FIT) Project

**Jonathan K Ehrman** , Steven J Keteyian, Henry Ford Hosp, Detroit, MI; Waqas Qureshi, Univ of Massachusetts, Shrewsbury, MA; Sherif Sakr, Univ of Tartu, Tartu, Estonia; Michelle C Johansen, Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; Mouaz H Al-Mallah, Houston Methodist Hosp, Pearland, TX; Clinton A Brawner, Henry Ford Hosp, Detroit, MI

4:25 PM

Q & A

4:30 PM

Exercise Capacity and All-Cause Mortality in Remote Indigenous and Non-Indigenous Populations

**Donald D Chang** , The Univ of Queensland-Ochsner Clinical Sch, New Orleans, LA; Nadarajah Kangaharan, Jason Forde, Daniel Goh, Harendran Elangovan, Nimisha Manek, Claudia Arauz, Stephen Brady, Alice Springs Hosp, Alice Springs, Australia; Prashanthan Sanders, Univ of Adelaide, Norwood, SA, Australia; Christopher X Wong, Univ of Adelaide and Royal Adelaide Hosp, Adelaide, Australia

4:40 PM

Q & A

4:45 PM

Poor Exercise Performance in Obese Adolescents: Is Cardiac Reserve Really Compromised Because of Obesity?

**Takeshi Tsuda** , Gina D'Aloisio, Alfred I. DuPont Hosp for Children, Wilmington, DE

4:55 PM

Q & A

# Abstract Oral Session

## CH.AOS.496 - T. Duckett Jones Memorial Lecture

#### Nutter Theatre

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Charles I Berul, Washington, DC

3:45 PM

Moderator

Shelley D Miyamoto, Aurora, CO

3:45 PM

Moderator

Sarah D De Ferranti, Boston, MA

3:45 PM

T. Duckett Jones Memorial Lecture

Craig A Sable, Potomac, MD

4:10 PM

Q&A

4:15 PM

Understanding the True Fate of the Systemic Right Ventricle: Late Outcome Differences Between Complete and Congenitally-Corrected Transposition of the Great Arteries

**Alexandra van Dissel** , AmsterdamUMC, Amsterdam, Netherlands; Alexander Opotowsky, Brigham and Women's Hosp and Children's Hosp Boston, Boston, MA; Jamil A Aboulhosn, UCLA, Los Angeles, CA; Martijn Kauling, Erasmus MC, Rotterdam, Netherlands; Michael G Earing, Childrens Hosp Wisconsin, Milwaukee, WI; Eric Krieger, Univ of Washington and Seattle Children's, Seattle, WA; Sangeeta Shah, Ochsner Medical Ctr, Harvey, LA; Tripti Gupta, Ochsner Medical Ctr, New Orleans, LA; Fred H Rodriguez, Sibley Heart Ctr Cardiology, Atlanta, GA; Anitha John, Childrens Nation Med Ctr, Washington, DC; Timothy Cotts, Univ of Michigan, Ann Arbor, MI; William Aaron Kay, Krannert Inst of Cardiology, Indianapolis, IN; Patti Woods, Knight Cardiovascular Inst, Portland, OR; Jeremy Robert Nicolarsen, Univ of Chicago Med. Ctr, Chicago, IL; Berardo Sarubbi, Monaldi Hosp, Naples, Italy; Petra Antonova, Univ Hosp Motol, Prague, Czech Republic; Susan M Fernandes, Stanford Univ, Palo Alto, CA; Jasmine Grewal, Vancouver General Hosp and St. Paul's Hosp, Vancouver, BC, Canada; Jonathan W Cramer, Childrens Hosp Omaha, Omaha, NE; Paul Khairy, Montreal Heart Inst, Montreal, QC, Canada; Pastora Gallego, Hosp Virgen Del Rocio, Sevilla, Spain; Craig Stanford Broberg, Knight Cardiovascular Inst, Portland, OR

4:25 PM

Q & A

4:30 PM

Physical Functioning And Quality Of Life In Different Congenital Heart Defects: Comparative Analysis In 3,589 Patients From 15 Countries

**Philip Moons** , Koen Luyckx, KU Leuven - Univ of Leuven, Leuven, Belgium; Corina Thomet, Inselspital - Bern Univ Hosp, Bern, Switzerland; Werner Budts, KU Leuven - Univ of Leuven, Leuven, Belgium; Junko Enomoto, Tokyo Univ, Tokyo, Japan; Maayke A Sluman, Univ of Amsterdam, Amsterdam, Netherlands; Chun-Wei Lu, Baylor Coll of Med, Houston, TX; Jamie L Jackson, Nationwide Childrens Hosp, Columbus, OH; Paul Khairy, Montreal Heart Inst, Montreal, QC, Canada; Stephen Cook, Helen DeVos Children's Hosp, Grand Rapids, MI; Shanthi Chidambarathanu, KU Leuven - Univ of Leuven, Mogappair, Tamil Nadu 600101, India; Luis E Alday, Hosp Aeronautico, Cordoba, Argentina; Katrine Eriksen, Oslo Univ Hosp - Rikshospitalet, Oslo, Norway; Mikael Georg Dellborg, Sahlgrenska Univ Hosp, Gothenburg, Sweden; Malin Berghammer, Univ West, Trollhättan, Sweden; Bengt Johansson, Vasterbottens Lans Landsting, Umea, Sweden; Andrew Mackie, Univ of Alberta, Edmonton, AB, Canada; Samuel Menahem, Royal Children's Hosp, Parkville Vic, Australia; Maryanne Caruana, Mater Dei Hosp, Msida, Malta; Gruschen Veldtman, King Faisal Specialist Hosp, Riyadh, Saudi Arabia; Alexandra Soufi, Louis Pradel Hosp, Hospices civils de Lyon, Lyon, France; Susan M Fernandes, Stanford Univ, Palo Alto, CA; Kamila White, Univ of Missouri-St. Louis, Saint Louis, MO; Edward Callus, IRCCS Policlinico San Donato, Milan, Italy; Shelby Kutty, Johns Hopkins Med, Baltimore, MD; Fouke Ombelet, KU Leuven - Univ of Leuven, Leuven, Belgium; Silke Apers, KU Leuven, Leuven, Belgium; Adrienne Kovacs, Oregon Health & Science Univ, Portland, OR; on behalf of the APPROACH-IS consortium and ISACHD

4:40 PM

Q & A

4:45 PM

Determining the Risk of Developing Rheumatic Heart Disease Following a Negative Screening Echocardiogram

**Meghan Zimmerman** , Children's Natl Health System, Washington, DC; Amy Scheel, Emory Sch of Med, Atlanta, GA; Alyssa Dewyer, Virginia Polytechnic Inst and State Univ, Blacksburg, VA; Emmy Okello, Uganda Heart Inst, Kampala, Uganda; Craig A Sable, Childrens Natl Medical Ctr, Potomac, MD; Andrea Z beaton, Cincinnati Childrens Hosp Medic, Washington, DC

4:55 PM

Q & A

# Abstract Oral Session

## SA.AOS.499 - William W.L. Glenn Lecture

#### 109AB

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Michael P Fischbein, Stanford, CA

3:45 PM

Moderator

Linda J Shore-lesserson, Manhasset, NY

3:45 PM

William W.L. Glenn Lecture

Joseph E Bavaria, Philadelphia, PA

4:10 PM

Q & A

4:15 PM

Association Between Blood Product Transfusion and In-Hospital Clinical Outcomes in Patients Undergoing Type A Aortic Dissection Repair in the United States

**Eirini Apostolidou** , Frank W Sellke, Herbert D Aronow, Alpert Medical Sch of Brown Univ, Providence, RI; Dhaval Kolte, Massachusetts General Hosp and Harvard Medical Sch, Boston, MA; Kevin F Kennedy, Saint Luke's Mid America Heart Inst, Univeristy of Missuri- Kansas City, Overland Park, KS; Neel R Sodha, James G Fingleton, Afshin Ehsan, Alpert Medical Sch of Brown Univ, Providence, RI

4:25 PM

Q&A

4:30 PM

Androgen Activates Tgf-beta Induced Aortic Smooth Muscle Differentiation in Thoracic Aortic Aneurysm of Marfan Syndrome Male Mice

**Yasushi Tashima** , Stanford Univ, Palo Alto, CA

4:40 PM

Q&A

4:45 PM

Updated Risk Prediction Model for Acute Type B Aortic Dissection

**Toru Suzuki** , Univ of Leicester, Leicester, United Kingdom; Arturo Evangelista, Hosp vall d´Hebron, Barcelona, Spain; Alan C Braverman, Washington Univ Med Sch, Saint Louis, MO; Kevin M. Harris, Minneapolis Heart Inst Fndn, Minneapolis, MN; Eduardo Bossone, Univ of Hosp Salerno, Lauro, Italy; Raffi Bekeredijan, Robert-Bosch Krankenhaus, Stuttgart, Germany; Stuart J Hutchison, Univ of Calgary, Calgary, AB, Canada; Dan Gilon, Hadassah Medical Organization, Jerusalem, Israel; Daniel G Montgomery, Kim Eagle, Univ of Michigan, Ann Arbor, MI; Christina Fanola, Univ of Minnesota, Minneapolis, MN; Truls Myrmel, The Arctic Univ of Norway, Tromso, Norway; Patrick O'Gara, Brigham & Women's Hosp, Boston, MA; Marc Schermerhorn, Beth Israel Deaconess Medical Ctr, Needham, MA; Roland R Van Kimmenade, RadboudUMC, Weert, Netherlands Antilles; Christoph Nienaber, Royal Brompton Hosp, London, United Kingdom; Eric Michael Isselbacher, Massachusetts General Hosp, Boston, MA

4:55 PM

Q&A

# Cardiovascular Seminar

## EP.CVS.528 - Application of Epidemiologic Methods to Address Controversies in Care, Disease Burden and Policy

#### 201C

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Kiarri N Kershaw, Chicago, IL

3:45 PM

Moderator

Sandeep Das, Dallas, TX

3:45 PM

Using Data Science to Improve Health for All

Robert M Califf, Durham, NC

3:57 PM

The Rise of Genome Interpretation for Cardiovascular Disease

Amit V Khera, Cambridge, MA

4:09 PM

Pragmatic Trial: The ADAPTABLE Trial

Adrian F Hernandez, Durham, NC

4:21 PM

Cost Effectiveness When Randomized Trials Can't (won't) Be Done

Andrew Moran, San Francisco, CA

4:33 PM

Stress Management RCTs Among Racial and Ethnic Groups

Tanya M Spruill, New York, NY

4:45 PM

Q & A

# Cardiovascular Seminar

## PH.CVS.480 - Clinical Controversies in Pulmonary Hypertension

#### 102AB

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Vinicio A De Jesus Perez, Palo Alto, CA

3:45 PM

Moderator

Corey Ventetuolo, Providence, RI

3:45 PM

Moderator

William Oldham, Boston, MA

3:45 PM

Oral Anticoagulant Therapy and Digoxin

Steeve Provencher, Quebec, QC, Canada

4:00 PM

PAH Specific Medications in Non-PAH PH

Marco Guazzi, Milano, Italy

4:15 PM

Role of Genetic Screening in Incident PAH and Determinants of Survival, and Screening for PH in Asymptomatic Mutation Carriers

Mary P Mullen, Boston, MA

4:30 PM

Significance of a Low DLCO in IPAH, PVOD, HFpEF and CTEPH

Harm J Bogaard, Amsterdam

4:45 PM

Discussion

# Cardiovascular Seminar

## IN.CVS.387 - Cutting Edge in Interventional Heart Failure

#### 107AB

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Shaline Rao, New York, NY

3:45 PM

Moderator

Holger Thiele, Leipzig

3:45 PM

Panel Participant

Jason N KATZ, Chapel Hill, NC

3:45 PM

Interventional Therapies in HFpEF: Role of LA Pressure Reduction

Daniel Burkhoff

3:59 PM

Panel Discussion

4:03 PM

The Potential of Intramyocardial Stem Cell Therapy in HFrEF

Amish N Raval, Madison, WI

4:17 PM

Panel Discussion

4:21 PM

Rationale Behind TAVR UNOAD

Ernest Spitzer

4:35 PM

Panel Discussion

4:39 PM

Supporting the Right Heart in Cardiogenic Shock

Sara C Martinez, Olympia, WA

4:53 PM

Panel Discussion

# Cardiovascular Seminar

## AC.CVS.352 - Great Debates in the Treatment of Patients with Stable Ischemic Heart Disease

#### 103A

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Matthew A Cavender, Chapel Hill, NC

3:45 PM

Moderator

Shun Kohsaka, Tokyo, Japan

3:45 PM

Moderator

Brittany Zwischenberger, NC

3:45 PM

Wait a Minute: Revascularization is Superior to Optimal Medical Therapy Alone

Pedro Moreno, new york, NY

3:53 PM

Discussion

3:58 PM

Case Closed: Optimal Medical Treatment is the Ideal Initial Strategy in Stable CAD

David Maron, Nashville, TN

4:06 PM

Discussion

4:11 PM

Diabetic Patients With Multivessel Disease Should Undergo CABG

Michael E Farkouh, Toronto, ON, Canada

4:19 PM

Discussion

4:24 PM

PCI Still Has a Role for Diabetic Patients With Multivessel Disease

Warren Cantor, Newmarket, ON, Canada

4:32 PM

Discussion

4:36 PM

The DAPT Score Should Be Used to Determine Duration of DAPT Post PCI

Robert Yeh, Boston, MA

4:44 PM

Discussion

4:48 PM

The New Generation Stents Have Obviated the Need for Long Term DAPT Following PCI in Stable Ischemic Heart Disease

Sripal Bangalore, New York, NY

4:56 PM

Discussion

# Cardiovascular Seminar

## EA.CVS.64 - Guideline Essentials - Top 5 Points from Recent Guideline/Consensus Document You Need to Know

#### Heart Theater

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Rachel J Lampert, New Haven, CT

3:45 PM

Moderator

Hugh Calkins, Baltimore, MD

3:45 PM

Syncope Guidelines

Win Kuang K Shen, Phoenix, AZ

3:55 PM

AF Guidelines Focused Update

Katherine MURRAY, Nashville, TN

4:05 PM

Ventricular Arrhythmia and Prevention of Sudden Death GuideLines

Sana Al Khatib, Durham, NC

4:15 PM

Arrhythmogenic Cardiomyopathies Consensus Document

Julia INDIK, Tucson, AZ

4:25 PM

Bradycardia and Conduction Delay

Fred Kusumoto, Jacksonville, FL

4:35 PM

EHRA Device Detected Subclinical Tachycardias

Bulent Gorenek, Eskisehir, Turkey

4:45 PM

Q&A

# Cardiovascular Seminar

## IM.CVS.437 - Heart Disease in Women: Focus on Imaging

#### 108B

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Gautham P Reddy, Seattle, WA

3:45 PM

Moderator

Carole Dennie, Ottawa, ON, Canada

3:45 PM

Challenges of Noninvasive Detection of Heart Disease in Women

Gautham P REDDY, Seattle, WA

4:00 PM

Diagnosis of Ischemic Heart Disease in Women

Gregory Kicska, Seattle, WA

4:15 PM

Diagnosis of Nonischemic Heart Disease in Women

Susan K Hobbs, Rochester, NY

4:30 PM

CT and MR Imaging in Pregnancy

Diana Litmanovich, Boston, MA

4:45 PM

Discussion

# Cardiovascular Seminar

## HY.CVS.432 - Microbiota and Hypertension: What Bugs You?

#### 108A

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Dominic Raj, Washington, DC

3:45 PM

Moderator

Costantino Iadecola, New York, NY

3:45 PM

GUT Microbiome and Blood Pressure

Katie A Meyer, Kannapolis, NC

4:10 PM

Brain-Gut-Bone Marrow Axis: Implications for Hypertension and Related Therapeutics

Mohan K RAIZADA, Gainesville, FL

# Cardiovascular Seminar

## QU.CVS.492 - Peddling EBM in the Era of Fake News and Dr. Google

#### 202AB

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Tracy Wang, Durham, NC

3:45 PM

Moderator

Michael P THOMPSON, Ann Arbor, MI

3:45 PM

Landscape of the Medical Googlesphere

Raina Merchant, Philadelphia, PA

4:00 PM

Medical Misinformation: Challenges in Clinical Practice

Joseph A Hill, Dallas, TX

4:15 PM

The Aftermath of Scientific Fraud: Impact on Public Perception of Medicine

Peter W Groeneveld, Philadelphia, PA

4:30 PM

Social Networks in Medicine: Challenges and Opportunities

Annabelle Santos Volgman, Chicago, IL

4:45 PM

Beating Dr. Google: Strategies to Build Trust and Introduce EBM in the Skeptical Patient

Shannon M Dunlay, Rochester, MN

# Cardiovascular Seminar

## VA.CVS.382 - The Morning After Vascular Surgery: Did I Take Appropriate Precautions?

#### 103C

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Peter Henke, ann arbor, MI

3:45 PM

Moderator

Elizabeth A Jackson, Birmingham, AL

3:45 PM

Case Type Risk Stratification and Consideration of Prehab for Vascular Patients?

Elizabeth A Jackson, Birmingham, AL

4:00 PM

What is Best Preop Prep to Prevent po MI?

Pj Devereaux, ON, Canada

4:15 PM

MINS -- Does it Really Matter?

Kirsten Fleischmann, San Francisco, CA

4:30 PM

How Do We Best Treat po MI?

Hitinder S Gurm, Ann Arbor, MI

4:45 PM

Case Presentation for po MI after Major Vascular Surgery

Robert Beaulieu, Ann Arbor, MI

# Cardiovascular Seminar

## HF.CVS.98 - The Road Home: Successful Treatment of Acute Decompensated Heart Failure

#### 105AB

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Steven Hollenberg, Camden, NJ

3:45 PM

Moderator

Deborah L Crabbe, Philadelphia, PA

3:45 PM

Heart Failure in the ER: Triage and Treatment

Barbara A Pisani, Winston Salem, NC

4:00 PM

Wet to Dry: Pathways to Decongestion During Hospitalization

Lynne W Stevenson, Nashville, TN

4:15 PM

PIONEERING the Use of ARNI for ADHF- When and Which Patient?

Kavita Sharma, Baltimore, MD

4:40 PM

Debate: Current CMS Processes for Developing Quality Metrics With Contractors Need a Major Revision

Gregg C Fonarow, Los Angeles, CA

4:50 PM

Q&A

# Cardiovascular Seminar

## CM.CVS.398 - What to Do Next? Moving from Risk to Benefit in Guidelines

#### 204AB

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

James L Januzzi, Wellesley Hills, MA

3:45 PM

Primary Prevention Statins: Absolute Risk Reduction

George Thanassoulis, Mont-royal, QC, Canada

4:00 PM

SecondaryPrevention: NNT & NNH to Estimate Net Benefit From LDL-C Lowering Drugs

Jennifer G ROBINSON, Iowa City, IA

4:15 PM

Hypertension Treatment Guided by Considering Benefit and Harms

Johan Sundstrom, Uppsala, Sweden

4:30 PM

Incorporating Consideration of Net Benefit into GuideLines

Clyde W Yancy Jr., Chicago, IL

4:45 PM

Diabetes - Benefit and Harms Endpoints When Deciding on an SGLPT-2 or GLP-1 Inhibitor

Sadiya S. Khan, Oak Park, IL

# Cardiovascular Seminar

## LF.CVS.400 - Why Doesn't My Patient Respond to Exercise? Gleaning Insights from Failures

#### 201AB

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Paul Poirier, Quebec, QC, Canada

3:45 PM

Moderator

Benjamin D LEVINE, Dallas, TX

3:45 PM

Clinical Cases: Responders and Non Responders to Exercise Intervention

Patrice Brassard, Québec, QC, Canada

3:50 PM

Why So Much Inaction Since HF-ACTION?

William K Cornwell II, Aurora, CO

4:02 PM

Q&A

4:04 PM

Thick Hearts Can't Keep Up: Exercise Limitations in Hypertrophic Cardiomyopathy

Katrin Dias, Dallas, TX

4:16 PM

Q&A

4:18 PM

Challenges With Exercise Training in HFpEF - Can We Kick the Heart into Gear?

Satyam Sarma, Dallas, TX

4:30 PM

Q&A

4:32 PM

The Influence of Exercise Training Characteristics on Metabolic Risk Factors and CVD Outcomes

Martin Halle, Munich

4:44 PM

Q&A

4:46 PM

Does Gender Impact the Response to Exercise Training?

Erin Howden, Melbourne, Australia

4:58 PM

Q&A

# Early Career

## IN.EC.322 - CLCD Early Career Ancillary Session: Working Across the Aisle ? Collaborating with Industry and Alternate Career Pathways

#### 112AB

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Waqas Qureshi, Winston Salem, NC

3:45 PM

Moderator

Janice Y Chyou, New York, NY

3:45 PM

Working With Industry: Effective Collaboration to Advance Science and Care While Managing Conflicts of Interests

Javed Butler, Atlanta, GA

3:55 PM

Working With the FDA and Regulatory Agencies: Insights and Opportunities

William H Maisel, Silver Spring, MD

4:06 PM

Innovation and Collaboration: Industry Perspective

Ron Waksman, Washington, DC

4:17 PM

Transitioning to a Career in Industry

Alan Cheng, Mounds View, MN

4:28 PM

Transitioning to a Career in Health Care Management

John J Warner, Dallas, TX

4:50 PM

Discussion

# Featured Science

## FS.AOS.03 - ACS & CAD: From Out of Hospital Arrest to Chronic Management

#### 111AB

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

James A de Lemos, Dallas, TX

3:45 PM

Moderator

Harmony Reynolds, New York, NY

3:45 PM

Early Coronary Angiography versus No Early Coronary Angiography for Post-Cardiac Arrest Patients Without ST-Segment Elevation: The PEARL Study

**Karl B Kern** , Univ of Arizona, Tucson, AZ; Peter Radsel, Univ Medical Ctr Ljubljana, Ljubljana, Slovenia; David B. Seder, Maine Medical Ctr, Portland, ME; Jacob C Jentzer, Mayo Clinic, Rochester, MN; Kwan Lee, Univ of Arizona, Tucson, AZ; Dion Stub, Alfred Hosp, Melbourne, Australia; Chiu-Hsieh Hsu, Univ of Arizona, Tucson, AZ; Marko Noc, Univ Medical Ctr Ljubljana, Ljubljana, Slovenia

3:53 PM

Discussion

3:56 PM

Effects of Intracoronary Recombinant Human Prourokinase or Tirofiban on the Coronary Flow During Primary PCI for the Acute Myocardial Infartion

**Dong Huang** , Juying Qian, Zhongshan Hosp, Shanghai, China; Zongjun Liu, Putuo Hosp, Shanghai, China; Yawei Xu, No. 10 Hosp, Shanghai, China; Zengyong Qiao, Fengxian District Central Hosp, Shanghai, China; Junbo Ge, Zhongshan hospital, Shanghai, China

4:04 PM

Discussion

4:07 PM

Dobutamine Stress Echocardiography Ischaemia as a Predictor of the Placebo-Controlled Efficacy of Percutaneous Coronary Intervention in Stable Coronary Artery Disease: The Stress Echo-Stratified Analysis of ORBITA

**Rasha Kadem Al-lamee** , Matthew Shun-Shin, James Howard, Alexandra Nowbar, Christopher Rajkumar, David Thompson, Sayan Sen, Imperial Coll NHS Trust, London, United Kingdom; Sukh Nijjer, Imperial Coll; Ricardo Petraco, John Davies, Imperial Coll NHS Trust, London, United Kingdom; Thomas Keeble, Kare Tang, Essex Cardiothoracic Ctr, Basildon; Iqbal Malik, Imperial Coll Healthcare; Nina Bual, Christopher Cook, Imperial Coll NHS Trust, London, United Kingdom; Yousif Ahmad, Imperial Coll London, London; Henry Seligman, Imperial Coll NHS Trust, London, United Kingdom; Andrew Sharp, Imperial Coll NHS Trust, Cardiff, United Kingdom; Suneel Talwar, Royal Bournemouth and Christchurch NHS Trust, Bournemouth, United Kingdom; Ravi Assomull, Graham Cole, Imperial Coll NHS Trust, London, United Kingdom; Niall G Keenan, Brompton Hosp, London; Gajen Sunthar Kanaganayagam, Imperial Coll Healthcare, London; Joban S Sehmi, Imperial Coll, London, United Kingdom; Roland Wensel, Natl Heart & Lung Inst, London, United Kingdom; Frank Harrell, Vanderbilt Univ Sch of Med, Nashville, TN; Jamil Mayet, Imperial Coll Healthcare, London; Simon Thom, Imperial Coll London, London; Justin E Davies, Intl Cte Circulatory Health, London, United Kingdom; Darrel Francis, Imperial Coll, London, United Kingdom

4:15 PM

Discussion

4:18 PM

One-Year Outcomes of Angina Management Guided by Invasive Coronary Function Testing (CORMICA)

Tom J Ford, Univ of Glasgow, Glasgow, United Kingdom; Bethany Stanley, Inst of Health and Wellbeing, Glasgow, United Kingdom; Novalia Sidik, Univ of Glasgow, Glasgow, United Kingdom; Richard Good, Paul Rocchiccioli, Margaret McEntegart, Stuart Watkins, Hany Eteiba, Aadil Shaukat, Mitchell Lindsay, Keith Robertson, Stuart Hood, Golden Jubilee Natl Hosp, Glasgow, United Kingdom; Ross McGeoch, Univ Hosp Hairmyres, Glasgow, United Kingdom; Robert McDade, Golden Jubilee Natl Hosp, Glasgow, United Kingdom; Eric Yii, Peter McCartney, David Corcoran, Damien Collison, Christopher Rush, Naveed Sattar, Univ of Glasgow, Glasgow, United Kingdom; Alex McConnachie, Inst of Health and Wellbeing, Glasgow, United Kingdom; Rhian M Touyz, Keith G. Oldroyd, **Colin Berry** , Univ of Glasgow, Glasgow, United Kingdom

4:26 PM

Discussion

4:29 PM

Rivaroxaban Plus Aspirin versus With Aspirin in Patients With Prior Percutaneous Coronary Intervention (PCI): Insights From the COMPASS Trial

**Kevin R Bainey** , Univ of Alberta, Edmonton, AB, Canada; Scott D Berkowitz, Bayer US LLC, Chapel Hill, NC; Deepak L Bhatt, Brigham and Women's Hosp, Boston, MA; John W Eikelboom, McMaster Univ HGH, Hamilton, ON, Canada; Keith A Fox, Cardiovascular Res, Nethy Bridge, United Kingdom; Basil S Lewis, Lady Davis Carmel Med Ctr, Haifa, Israel; Tamara Marsden, McMaster Univ - PHRI, Hamilton, ON, Canada; Eva Muehlhofer, McMaster Univ - PHRI, Hamilton, ON, Canada, Leverkusen; Dragos Vinereanu, Univ Carol Davila, Bucharest; Petr Widimsky, Charles Univ, Prague 10, Czech Republic; Robert C Welsh, Mazankowski Alberta Heart Inst, Edmonton, AB, Canada

4:37 PM

Discussion

4:40 PM

Ticagrelor Monotherapy versus Standard Dual Antiplatelet Therapy After Drug-Eluting Coronary Stent Implantation: A Systematic Review and Individual Patient Data Meta-Analysis From the Single versus Dual Antiplatelet Therapy (SIDNEY) Collaboration

**Marco Valgimigli** , Bern Univ Hosp, Bern, Switzerland; Peter Jueni, Applied Health Res Ctr, Li Ka Shing Knowledge Inst of St Michael's Hosp,, Toronto, ON, Canada; Roxana Mehran, ICAHN Sch of Med Mt. Sinai, New York, NY

4:48 PM

Discussion

4:50 PM

Stent Thrombosis After Percutaneous Coronary Intervention Among Patients With Atrial Fibrillation Treated With Apixaban or Aspirin: Insights From the AUGUSTUS Trial

**Renato D Lopes** , Duke Clinical Res, Durham, NC; Daniel Wojdyla, Christopher Bull Granger, Duke Clinical Res Inst, Durham, NC; Shaun Geoffrey Goodman, St Michael's Hosp, Toronto, ON, Canada; Ronald Aronson, Bristol-Myers Squibb, Lawrenceville, NJ; Stephan Windecker, Roxana Mehran, Swiss Cardiovascular Ctr Bern, Bern; John H Alexander, Duke Clinical Res Inst, Durham, NC

4:58 PM

Discussion

# Featured Science

## FS.AOS.04 - Late Breaking Trials in EP and LV Function

#### 118A

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Christine M Albert, W Hollywood, CA

3:45 PM

Apple Watch App Identifies Clinically Important Arrhythmias Other Than Atrial Fibrillation: Results From the Apple Heart Study

**Marco Valentin Perez** , Stanford Univ, San Jose, CA; Kenneth Mahaffey, Haley Hedlin, Stanford Univ, Stanford, CA; John S Rumsfeld, American Coll of Cardiology, Denver, CO; Ariadna Garcia, Todd Ferris, Stanford Univ, Stanford, CA; Vidhya Balasubramanian, Stanford Univ, Palo Alto, CA; Andrea M Russo, Cooper Univ Hosp, Moorestown, NJ; Amol Rajmane, Stanford Univ, Stanford, CA; Lauren Cheung, Apple Inc., Cupertino, CA; Grace Hung, Justin Lee, Stanford Univ, Stanford, CA; Peter R Kowey, Lankenau Medical Ctr, Wynnewood, PA; Nisha Talati, Stanford Univ, Stanford, CA; Divya Nag, Apple Inc., Cupertino, CA; Santosh Gummidipundi, Stanford Univ, Stanford, CA; Alexis L Beatty, Stanford Univ, Stanford, CA, Cupertino, CA; Melanie T. Hills, Stop Afib, Greenwood, TX; Sumbul Desai, Stanford Medical Ctr, Palo Alto, CA; Christopher Bull Granger, Duke Clinical Res Inst, Durham, NC; Manisha Desai, Stanford Univ, Stanford, CA; Mintu Turakhia, Stanford Univ, Palo Alto, CA

4:00 PM

Apixaban versus Warfarin for Stroke Prevention in Patients With End Stage Renal Disease on Hemodialysis and Atrial Fibrillation: Results of a Randomized Clinical Trial Assessing Safety

**Sean D Pokorney** , Duke Clinical Res Inst, Durham, NC; Glenn M Chertow, Stanford Univ, Palo Alto, CA; Hussein Al-khalidi, Duke Univ, Durham, NC; Dianne Gallup, Pat Dignacco, Duke Clinical Res Inst, Durham, NC; Kurt Mussina, Fresenius, Waltham, MA; Nisha Bansal, Univ of Washington, Seattle, WA; Crystal A Gadegbeku, David Garcia, Temple Univ, Philadelphia, PA; Charlotte Jones-Burton, Bristol-Myers Squibb, Lawrenceville, NJ; Renato D Lopes Sr., Duke Clinical Res, Durham, NC; Kenneth W Mahaffey, Stanford Univ, Stanford, CA; John Middleton, Duke Univ, Durham, NC; Donna Mills, Bristol-Myers Squibb, Lawrenceville, NJ; Jennifer A Rymer, Duke, Durham, NC; Ravi Thadhani, Cedars-Sinai Medical Ctr, Los Angeles, CA; Kevin Lindsey Thomas, Duke Univ, Durham, NC; Wolfgang Christoph Winkelmayer, Baylor Coll of Med, Houston, TX; Christopher Bull Granger, Duke Clinical Res Inst, Durham, NC

4:15 PM

Apixaban for Early Prevention of Recurrent Embolic Stroke and Hemorrhagic Transformation in Patients With Atrial Fibrillation: Results of the AREST Trial

**Arthur J Labovitz** , Michael George Fradley, Univ of South Florida, Tampa, FL; David Rose, John N Meriwether, Univ of South Florida, Brookline, MA; Swetha Renati, Univ of South Florida, Tampa, FL; Ryan C Martin, Univ of South Florida, Tampa, FL, Atlanta, GA; Thomas Kasprowicz, Ryan Murtagh, Kevin Kip, Theresa M Beckie, Univ of South Florida, Tampa, FL; Marcus Stoddard, Andrea Bozeman, Univ of Kentucky, Louisville, KY; Tara McTigue, Univ of South Florida, Tampa, FL; Bonnie Kirby, Univ of South Florida, Tampa, FL, Tampa, FL; Nhi Tran, Univ of South Florida, Tampa, FL; William Burgin, USF, Tampa, FL

4:30 PM

Carvedilol Does Not Improve Exercise Performance in Fontan Patients: Results of a Cross Over Trial

**Ryan J Butts** , Univ of Texas Southwestern, Dallas, TX; Andrew M Atz, Medical Univ South Carolina, Mt Pleasant, SC; Nathanya BaezHernandez, Univ of Texas Southwestern, Dallas, TX; David L Sutcliffe, UT Southwestern Medical Sch, Dallas, TX; Joan Reisch, UT Southwestern Medical Ctr, Dallas, TX; Lynn Mahony, Univ of Texas Southwestern Med, Dallas, TX

4:45 PM

Randomized Controlled Trial of Testosterone Treatment on Left Ventricular Mass in Older Men With Low Testosterone

**Elizabeth Hutchins** , Los Angeles Biomedical Res Ctr, Torrance, CA; Susan S Ellenberg, Peter J. Snyder, Univ of Pennsylvania Perelman Sch of Med, Philadelphia, PA; Matthew J Budoff, Los Angeles Biomedical Res Ctr, Torrance, CA

# Frontiers in Science

## EA.FIS.603 - Arrhythmia Research Summit: Engineering Arrhythmia Innovations

#### 119AB

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Samir Saba, Pittsburgh, PA

3:45 PM

Moderator

Peng-Sheng Chen

3:45 PM

Keynote: The Future of Everything: How Innovation and Science will Transform Arrhythmia Care

Paul Wang, Palo Alto, CA

3:55 PM

Q&A

3:57 PM

Engineering Gene Therapies for Arrhythmias

J Kevin DONAHUE, Worcester, MA

4:02 PM

Q&A

4:03 PM

Stem cell derived cardiomyocytes as models or therapy

Joseph Wu, Stanford, CA

4:08 PM

Q&A

4:09 PM

Biologic pacemaking from stem cells

Deborah Lieu, Sacramento, CA

4:14 PM

Q&A

4:15 PM

From Virtual Modeling to Personalized Ablation

Natalia TRAYANOVA, Baltimore, MD

4:20 PM

Q&A

4:21 PM

New Frontiers in Optogenetics

Lior GEPSTEIN, Haifa, Israel

4:26 PM

Q&A

4:27 PM

The newest in connectivity and digital arrhythmia care

Mintu Turakhia, Palo Alto, CA

4:32 PM

Q&A

4:33 PM

Artificial Intelligence and the ECG: Are Machines Better than Human Reads?

Paul Friedman, Rochester, MN

4:38 PM

Q&A

4:39 PM

Towards Machine Learning Enhanced Arrhythmia Care

Rakesh Shiradkar, OH

4:44 PM

Q&A

4:45 PM

Cardiac Electrophysiology Under MRI Guidance

Henry Chubb, London, United Kingdom

4:50 PM

Q&A

4:54 PM

Virtual EP Reality

Jennifer Silva, Saint Louis, MO

4:59 PM

Q&A

# Frontiers in Science

## VA.FIS.402 - Frontiers in Science: Vascular Disease Summit: Vascular Diseases from Bench to Bedside

#### 103B

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Nicholas J Leeper, Stanford, CA

3:45 PM

Moderator

Naomi M Hamburg, Boston, MA

3:45 PM

Atherosclerosis in PAD: Similarities and Differences from other Vascular Beds

Luke P Brewster, Atlanta, GA

3:55 PM

Slowing the Progression of PAD With Medical Therapies

Aruna D Pradhan, Boston, MA

4:05 PM

Unpacking the Mechanisms of Lymphedema

Stanley Rockson, Stanford, CA

4:15 PM

Lymph Node Transfer for Lymphedema

Brett Carroll, Boston, MA

4:25 PM

Genetic Underpinnings of Venous Disease

Scott M DAMRAUER, Philadelphia, PA

4:35 PM

Emerging Treatment of Superficial Venous Disease

John Phillips, Powell, OH

4:45 PM

Panel Discussion

panel Panel Discussion, TX

# Joint Sessions

## EA.JS.1613 - Global Roundtable:Arrhythmias in Unique Circumstances (Cardiac Society of Australia and New Zealand, Mexican Society of Cardiology, Polish Cardiac Society and Romanian Society of Cardiology)

#### 121A

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Ana Maria Salvati, Buenos Aires, Argentina

3:45 PM

Atrial Arrhythmias in Ventricular Cardiomyopathies.

Diane Fatkin, Darlinghurst, Australia

4:00 PM

Primary Prevention of Sudden Cardiac Death in Heart Failure: Time For Improvement?

Jorge González, Guadalajara, Mexico

4:15 PM

New Additional Aspects of Atrial Fibrillation Revealed by the NOACs Trials

Dragos Vinereanu, Bucharest, Romania

4:30 PM

Genetic Testing in Families with Brugada Syndrom - A Clear Pool or a Muddy Puddle?

Tomasz Rechcinski, Poland

4:45 PM

Panel Discussion

# Main Event

## SA.ME.598 - Mitral Valve Therapies ? When Drugs are Not Enough

#### Main Event II

### Saturday, November 16, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Katherine Harrington, Plano, TX

3:45 PM

Moderator

alaide chieffo, Milan, Italy

3:45 PM

Case Presentation - Functional MR, reduced LVEF

Matthew W Sherwood, Arlington, VA

3:50 PM

Mitral regurgitation - Where to Begin?

William Abraham, Columbus, OH

4:00 PM

Multimodality Imaging for Innovative Mitral Therapies

Edwin Ho, Toronto, ON, Canada

4:15 PM

Transcatheter Approaches to Mitral Regurgitation: from Mitraclip to TMVR

Mayra Guerrero, Evanston, IL

4:30 PM

Surgical Advances in Mitral Valve Therapies

Steven Bolling, Ann Arbor, MI

4:45 PM

Panel Discussion

# Meet the Trialists

## CS.MT.01 - Meet the Trialists - ISCHEMIA Trials

#### EP Central

### Saturday, November 16, 2019, 3:45 PM - 4:30 PM

3:45 PM

ISCHEMIA

Judith S Hochman, New York, NY

3:45 PM

ISCHEMIA - QoL

John Spertus, Kansas City, MO

3:45 PM

ISCHEMIA-CKD

Sripal Bangalore, New York, NY

# FIT Event

## FIT.15 - Step In, Speak Out: The Art of Advocating for Yourself and Other Women

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Saturday, November 16, 2019, 4:00 PM - 4:45 PM

This is not a CME/CE certified session

# Hall

## HT.04 - Hot Topics in AI and Big Data

#### Health Innovation Pavilion, Heart Hub, Science and Technology Hall, Level 2

### Saturday, November 16, 2019, 4:00 PM - 4:50 PM

4:00 PM

Moderator

Rashmee Shah, UT

# Abstract Poster Session

## IN.APS.05 - Advances in Percutaneous Non-Coronary Therapies

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 4253

**Real-Word Outcomes Following Left Atrial Appendage Occlusion Using the Watchman** TM **Device: Analysis From the National Inpatient Sample**

**Antoine Addoumieh** , Altru Hosp, Grand Forks, ND; Mohamed Khayata, Cleveland Clinic, Cleveland, OH; Nour Tashtish, Sadeer Al-Kindi, Univ Hosp Cleveland Medical Ctr, Cleveland, OH; Saqer Alkharabsheh, Beni R Verma, Muhammad Mohsin Furqan, Allan L Klein, David Majdalany, Khaldoun Tarakji, Oussama Musbah Wazni, Cleveland Clinic, Cleveland, OH

4:30 PM

Board # 4254

Safety and Effectiveness of Trans-Catheter versus Surgical Aortic Valve Replacement in Nonagenarians With Severe Aortic Stenosis: A Systematic Review and Meta-Analysis

**Muhammad Junaid Ahsan** , Creighton Univ, Omaha, NE; Hafiz Muhammad Fazeel, Services Inst of Medical Sci., Lahore, Pakistan; Saad Ullah Malik, Univ of Arizona, Tucson, AZ; asim tameez ud din, Rawalpindi Medical Coll, Rawalpindi, Pakistan; Syeda Hassan, Fatima Jinnah Medical Univ, Lahore, Pakistan; Behram Ahmed Khan, Services Inst of Medical Sciences, Lahore, Pakistan; Mydah Sajid Hashmi, Army Medical Coll, Rawalpindi, Pakistan; Mohsin Mansoor Mirza, Creighton Univ, Omaha, NE

4:30 PM

Board # 4256

Short-term and Long-term Mortality After Transcatheter Aortic Valve Replacement for Severe Aortic Stenosis Among Patients With Malignancy: A Systematic Review and Meta-analysis

**Muhammad U Siddiqui** , Wajdi Bader, Marshfield Clinic, Rice Lake, WI; Muhammad D Siddiqui, Univ of South Dakota, Sioux Falls, SD; Ahmed K Pasha, Mayo Clinic Health System, North Mankato, MN; Mahrukh Siddiqui, Presence St Joseph Hosp, Chicago, IL

4:30 PM

Board # 4257

Predictors and Clinical Impact of Thrombocytopenia After Complete Percutaneous Transfemoral Transcatheter Aortic Valve Implantation

**Shinji Takahashi** , Naoyuki Yokoyama, Yusuke Watanabe, Taiga Katayama, Hirofumi Hioki, Teikyo Univ Sch of Med, Tokyo, Japan; Hirosada Yamamoto, Teikyo Univ Hosp, Tokyo, Japan; Kazuo Kawayugi, Ken Kozuma, Teikyo Univ, Tokyo, Japan

4:30 PM

Board # 4258

Impact of Right Ventricular Dysfunction on Outcomes After Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis

**Saif El Nawaa** , Texas Tech Univ HSC, Lubbock, TX; Wasawat Vutthikraivit, Texas Tech Health Sciences Ctr, Lubbock, TX; Pablo Paz, Texas Tech Univerdity Health Sciences Ctr, Lubbock, TX; Mohamed Elmassry, Texas Tech Univ Health S C, Lubbock, TX; M Rubayat Rahman, Texas Tech Univ, Lubbock, TX; Pattara Rattanawong, Univ of Hawaii, Honolulu, HI; Prapaipan Putthapiban, Einstein Medical Ctr, Philadelphia, PA; Barbara Mantilla, TBD, Lubbock, TX; Mohamed Zitun, Texas Tech Univ HSC, Lubbock, TX; Ahmed M. Souka, Univ of Cincinnati, Cincinnati, OH; Alay Tikue, Texas Tech Univ HSC, Lubbock, TX; Scott W Shurmur, Texas Tech Univ, Lubbock, TX

4:30 PM

Board # 4259

Utilization of Percutaneous Left Atrial Appendage Closure in Patient With Atrial Fibrillation in United States From 2007 to 2016: A Ten-year Analysis From National Database

**Lingling Wu** , Mount Sinai St Luke's and West Hosp, New York, NY; Yingying Zheng, The Brody Sch of Med at East Carolina, Greenville, NC; Faris I Haddadin, Kirtipal Bhatia, Mount Sinai St Luke's and West Hosp, New York, NY; Bharat Narasimhan, Mount Sinai St Luke's and West Hosp, New york, NY; Bing Yue, Claire Huang Lucas, Xin Wei, Mount Sinai St Luke's and West Hosp, New York, NY; Swiri Konje, Mount Sinai St Luke's and West Hosp, new york, NY; Kam Ho, Hassan Beydoun, Mount Sinai St Luke's and West Hosp, New York, NY; Wojciech Rzechorzek, Mount Sinai St. Luke's West, Chapel Hill, NC; Davendra Mehta, Mount Sinai St Luke's and West Hosp, New York, NY

4:30 PM

Board # 4260

The Effects of the LAMPOON Procedure on Flow in the Mitral Valve Anterior Leaflet Neo-Sinus

**Thomas F Easley** , Vahid Sadri, Pranav Dorbala, Georgia Inst of Technology, Atlanta, GA; Norihiko Kamioka, Emory Univ, Atlanta, GA; Vasilis Babaliaros, emory university, Atlanta, GA; Ajit P Yoganathan, Georgia Inst of Technology, Atlanta, GA

4:30 PM

Board # 4262

Northern New England'S Multicenter Experience With Percutaneous Coronary Intervention Among Patients With Coronary Artery Disease Undergoing Transcatheter Aortic Valve Replacement

**Jay Shah** , Jessica Kvasic, Paul Frey, David Butzel, Maine Medical Ctr, Portland, ME; Michael P Robich, Maine Medical Partners, Portland, ME; Reed Quinn, Maine Medical Ctr, Portland, ME; John Jayne, Dartmouth-Hitchcock Medical Ctr, Lebanon, NH; David J Malenka, Dartmouth-Hitchcock Med Ctr, Lebanon, NH; Samip Vasaiwala, Maine Medical Ctr, Portland, ME; The Northern New England Cardiovascular Disease Group

# Abstract Poster Session

## HY.APS.06 - Arterial Stiffness and Hypertension

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2196

The Perspective of Using the Genetic Risk Score in Prediction of Cardiovascular Risk in Patients With Arterial Hypertension

**Vadym Bondar** , Kateryna Chernyshova, Viktoriia Vasylets, Sergii Kolomiyets, Olena Kryzhanovska, Odessa Natl Medical Univ, Odessa, Ukraine

4:30 PM

Board # 2197

The Effects of Home Particulate Air Filtration on Blood Pressure: A Systematic Review

Dalia Walzer, New York Univ Medical Ctr, New York, NY; Terry Gordon, New York Univ Medical Ctr, Tuxedo, NY; Lorna Thorpe, New York Univ Medical Ctr, New York, NY; George Thurston, New York Univ Medical Ctr, Tuxedo, NY; Yuhe Xia, New York Univ Medical Ctr, New York, NY; Hua Zhong, New York Univ Medical Ctr, NYC, NY; Timothy R. Roberts, Judith S Hochman, **Jonathan D Newman** , New York Univ Medical Ctr, New York, NY

4:30 PM

Board # 2198

Eplerenone Improves Vascular Function, Arterial Stiffness and Rho-associated Kinase Activity in Patients With Idiopathic Hyperaldosteronism

**Shinji Kishimoto** , Yukihito Higashi, Hiroshima Univ, Hiroshima, Japan; Tatsuya Maruhashi, Hiroshima Univ, Hiroshima Japan, Japan; Masato Kajikawa, Haruki Hashimoto, Yuji Takaeko, Hiroshima Univ, Hiroshima, Japan; Takahiro Harada, Hiroshima Univ, Hiroshima city, Japan; Takayuki Yamaji, Farina Mohamad Yusoff, Yasuki Kihara, Hiroshima Univ, Hiroshima, Japan

4:30 PM

Board # 2199

Comparison of the Effects of Bromazepam, Alprazolam and Lorazepam on Noctural Blood Pressure and Heart Rate in Mild Hypertensive Patients

**Roberto Fogari** , Alfredo Costa, Angela D'Angelo, Matteo Cotta Ramusino, Daniele Bosone, Univ of Pavia, Pavia, Italy

4:30 PM

Board # 2200

A Blood Pressure-adjusted Stiffness Index, the Cardio-ankle Vascular Index (CAVI), Affects Nighttime Ambulatory Hemodynamics: The Coupling Study

**Takeshi Fujiwara** , Tomoyuki Kabutoya, Jichi Medical Univ, Shimotsuke, Japan; Hiroshi Kanegae, Genki Plaza Medical Ctr for Health Care, Tokyo, Japan; Satoshi Hoshide, Kazuomi Kario, Jichi Medical Univ, Shimotsuke, Japan

4:30 PM

Board # 2201

Oscar 2 and Spacelabs 90207/90217 Ambulatory Blood Pressure Monitors Misclassify Patients Based on New American Heart Association Guidelines

**V Patteson Lombardi** , Patrick C Reichhold, Jennifer L Cramer, Hannah P Harkness, Natalie J DeBell, Nicholas R Dietz, Donald L Pate, Univ of Oregon, Eugene, OR

4:30 PM

Board # 2202

The Sodium Voltage-Gated Channel Alpha Subunit Gene: Genotype-Phenotype Relationship for Blood Pressure and Potassium Excretion

**Maria Carolina Delgado-Lelievre** , Univ of Miami Medical Sch, Doral, FL; Lelievre A David, Divine Savior Acad, Doral, FL; Carlos Luis Delgado, Univ de Carabobo Medical Sch, Valencia, Venezuela, Bolivarian Republic of

4:30 PM

Board # 2203

Association of Dipping Status of Blood Pressure and Visual Defect in Patients With Normotensive Glaucoma

**Sung Il Im** , Hansu park, Kosin Univ Gospel Hosp, Busan, Korea, Republic of

4:30 PM

Board # 2204

Clonal Hematopoiesis of Indeterminate Prognosis (CHIP) in Patients With Therapy-Refractory Arterial Hypertension Undergoing Renal Denervation Therapy

**Alisha Haug** , Univ Hosp Frankfurt, Frankfurt Am Main, Germany; Michael Boehm, Univsklinikum des Saarlandes, Homburg; Lucas Lauder, Mathias Hohl, Felix Mahfoud, Saarland Univ Hosp, Homburg, Germany; Tina Rasper, Inst for Cardiovascular Regeneration, Frankfurt Am Main, Germany; Michael Rieger, Goethe Univ Frankfurt, Frankfurt Am Main, Germany; Lena Dorsheimer, Univ Hosp Frankfurt, Frankfurt Am Main, Germany; Florian Leuschner, Univ of Heidelberg, Heidelberg; Stefanie Dimmeler, Inst of Cardiovasular Regeneration, Frankfurt Am Main, Germany; Andreas M Zeiher, Klinikum d. J. W Goethe-Univ, Frankfurt Am Main, Denmark

4:30 PM

Poster Professor

Edward JOSEPH Lesnefsky Jr., Midlothian, VA

4:30 PM

Board # 2205

Impact of Estimated Pulse Wave Velocity and Its Response to Treatment on Survival: A Secondary Analysis of the Systolic Blood Pressure Intervention Trial

**Dimitrios Terentes-Printzios** , Natl and Kapodistrian Univ of Athens, Athens, Greece; Charalambos Vlachopoulos, Athens Medical Sch, Athens; Stephane Laurent, Hosp European Georges Pompidou, Paris, France; Peter Nilsson, Lund Univ, Sweden; Athanasios Protogerou, Konstantinos Aznaouridis, Natl and Kapodistrian Univ of Athens, Athens, Greece; Panagiotis Xaplanteris, Iosif Koutagiar, Hippokrateion Hosp, Athens, Greece; Hirofumi Tomiyama, Akira Yamashina, Tokyo Medical Univ, Tokyo, Japan; Dimitrios Tousoulis, Ippokrateio Hosp, Athens, Greece

# Abstract Poster Session

## EA.APS.07 - Atrial Fibrillation Risk Markers

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2036

CHA2DS2-VASc Score and Risk of Subacute (<1 Month) Atrial Fibrillation After Cardiac Surgery

**Stefania Sacchi** , Alessandra Bonaccorso, San Raffaele Univ Hosp, Milan, Italy; Marco Chiostri, Univ of Florence, Florence, Italy; Maria Avitabile, Iside Cartella, Anna Pistoni, Francesco Maranta, Carlo Meloni, Maria Grazia Pala, Domenico Cianflone, San Raffaele Univ Hosp, Milan, Italy

4:30 PM

Board # 2037

Advanced Interatrialblock as an Independent Marker of Left Atrial Fibrosis and Intra-Atrial Dyssynchrony: ECG-MRI Correlation

**Luisa Ciuffo Ciuffo** , Univ of New Mexico, Albuquerque, NM; Henrique Doria De Vasconcellos, Johns Hopkins, Baltimore, MD; Vanesa Bruña, Hosp Univrio Gregorio Marañón, CIBERCV, Madrid, Spain; Manuel Martínez-Sellés, Hosp Univrio Gregorio Marañón, CIBERCV and Univ Europea, Univ Complutense, Madrid, Spain; Susumu Tao, Johns Hopkins Univ, Baltimore, MD; David D. Spragg, Johns Hopkins, Baltimore, MD; Joseph E Marine, Johns Hopkins U Sch Medicin, Baltimore, MD; Ronald D Berger, Joao A Lima, Johns Hopkins Univ, Baltimore, MD; Hugh G Calkins, Johns Hopkins Univ Sch Med, Baltimore, MD; Antonio Bayés de Luna, Cardiovascular Res Fndn, Cardiovascular ICCC-Program, Res Inst Hosp de la Santa Creu i Sant Pau, IIB-Sant Pau, Barcelona, Spain; Hiroshi Ashikaga, Johns Hopkins Univ Sch of Med, Baltimore, MD

4:30 PM

Board # 2038

Cardiac Microstructural Abnormalities Increase Risk for Atrial Fibrillation

**Emmanuella Demosthenes** , Gerran Salto, Brigham and Women's Hosp, Boston, MA; Ewa Osypiuk, Plamen Stantchev, Birgitta Lehman, Boston Univ, Framingham, MA; Elizabeth H Kim, Cedars-Sinai Medical Ctr, Los Angeles, CA; Pranoti Hiremath, Johns Hopkins Med, Baltimore, MD; Susan Cheng, Cedars-Sinai Medical Ctr, Los Angeles, CA

4:30 PM

Board # 2039

Association Between Body Mass Index and Atrial Conduction Indices on Surface and Intracardiac Electrocardiogram in Patients With Supraventricular Arrhythmias

**Hatem Al Kassem** , Amrish Deshmukh, Zaid Aziz, Stephanie A. Besser, Cevher Ozcan, The Univ of Chicago, Chicago, IL

4:30 PM

Board # 2040

Diurnal Variation Detected in Paroxysmal Atrial Fibrillation

**Jonathan Kim** , Julian A Wolfson, Wendy Wang, Univ of Minnesota, Minneapolis, MN; Mary R Rooney, Univ of Minnesota Twin-Cities, Minneapolis, MN; Faye L Norby, Michael J Zhang, Univ of Minnesota, Minneapolis, MN; Alvaro Alonso, Emory Univ, Atlanta, GA; Pamela L Lutsey, Univ of Minnesota, Minneapolis, MN; Elsayed Z Soliman, Wake Forest Sch of Med, Winston Salem, NC; Lin Yee Chen, Univ of Minnesota, Minneapolis, MN

4:30 PM

Board # 2041

Relationship Between CHA2DS2-VASc Score and Long-Term Outcome of Catheter Ablation in Patients With Atrial Fibrillation

**Zahra Azizi** , Southlake Regional Health Ctr, Aurora, ON, Canada; Pouria Alipour, Southlake Regional Health Ctr, Newmarket, ON, Canada; Yaariv Khaykin, Southlake regional health centre, Richmond Hill, ON, Canada; Claire Jansen, Alona Avoulov, Sarah Donegan, Hodaya Lightstone, Stacey Morris, Sara Tamjidi, Sereena Nath, Southlake Regional Health Ctr, Aurora, ON, Canada; Andrea Chiocchini, Southlake Regional Health Ctr, Newmarket, ON, Canada; Maria Terricabras, Southlake Regional Health Ctr, Aurora, ON, Canada; Atul Verma, Southlake Regional Health Ctr, Newmarket, ON, Canada

4:30 PM

Board # 2042

Temporal Trends in Implantable Loop Recorder Use After Stroke in a Large Academic Health System

**Mostafa Al-Alusi** , Shaan Khurshid, Wyliena Guan, Priscilla R Lee, Ana Lipsanopoulos, Patrick T Ellinor, Christopher D Anderson, Steven A Lubitz, Massachusetts General Hosp, Boston, MA

4:30 PM

Board # 2043

High Risk Population Of Screen Detected Atrial Fibrillation

**Yoshiki Nagata** , Hokuriku Health Service Association, Toyama, Japan; Nicole Lowres, Heart Res Inst, Camperdown, Australia; Takashi Yamagami, Hongbing Wang, Hokuriku Health Service Association, Toyama, Japan; Don Nutbeam, Univ of Sydney, Sydney, Australia; Ben B Freedman, HEART RESEARCH INSTITUTE SYDNEY UNI, Sydney, Australia

4:30 PM

Board # 2044

Sex Differences in Presentation With Atrial Fibrillation: Findings From 30-day Ambulatory Monitoring in 27,512 Patients in Real-world Practice

**Andrea M Russo** , Cooper Medical Sch of Rowan Univ, Camden, NJ; Marek Dziubinski, Natan Napiorkowski, Olga Witkowska, Medicalgorithmics S.A., Warsaw, Poland; Linda Johnson, Lund Univ, Lund, Sweden

4:30 PM

Board # 2045

**HAS-BLED and CHA** 2 **Ds** 2 **-VASc Scores May be of Limited Clinical Utility Among Patients With Atrial Fibrillation and Evidence of Cerebral Amyloid Angiopathy**

**Robert C Ward** , Mayo Clinic, Rochester, MN; Shiva P Ponamgi, Mayo Clinic, Austin, MN; Stephen English, Christopher V Desimone, David Hodge, Joshua Slusser, Mayo Clinic, Rochester, MN; Alejandro A Rabinstein, Mayo Clinic Neurology, Rochester, MN; Jonathan Graff-Radford, Mayo Clinic, Rochester, MN; Samuel Asirvatham, Mayo Fndn, Rochester, MN; David R Holmes, Mayo Clinic, Rochester, MN

4:30 PM

Poster Professor

COLLEEN Johnson, New Orleans, LA

# Abstract Poster Session

## EP.APS.06 - Big Data and Global-omics Approach to Cardiovascular Disease Epidemiology

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 3083

Using Natural Language Processing to Accurately Identify Aortic Stenosis in a Large, Integrated Healthcare Delivery System

**Matthew D Solomon** , Grace Tabada, Amanda Allen, Sue Hee Sung, Kaiser Permanente, Oakland, CA; Alan S Go, Kaiser Permanente Northern Cal, Oakland, CA

4:30 PM

Board # 3085

Can Machine Learning Predict Chest Pain Readmissions?

**Anvi Raina** , Hena Patel, Natasha Rana, Georges Compagnon, Proddutur R Reddy, Rush Univ Medical Ctr, Chicago, IL

4:30 PM

Board # 3086

The Cardiac Arrest Prediction Model Based on Weather Forecast by Machine Learning

**Takahiro Nakashima** , Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Soshiro Ogata, NCVC, Suita, Japan; Teruo Noguchi, Natl Cardiovascular Ctr, Suita, Japan; Satoshi Yasuda, Natl Cereb Cardiovascular Ctr, Osaka, Japan; Yoshio Tahara, Natl Cardiovascular Ctr, Osaka, Japan; Ken Nagao, Nihon university surugadai hospital, Tokyo, Japan; Kunihiro Nishimura, NCVC, Suita, Japan; Hiroshi Nonogi, Shizuoka General Hosp, Shizuoka, Japan; Koji Iihara, Kyushu Univ Hosp, Fukuoka, Japan; Sunao Kojima, Kawasaki Medical Sch, Okayama, Japan

4:30 PM

Board # 3087

Automated Disease Detection Using Document Classification Outperforms Encounter-Level Diagnostic Codes for Cardiovascular Diseases

**Max Homilius** , One Brave Idea/Brigham and Women's Hosp, Boston, MA; Alexander J Blood, Brian H Park, Daniel Yazdi, Brigham and Women's Hosp, Boston, MA; Jason N Veytsman, Calum A MacRae, Rahul C Deo, One Brave Idea/Brigham and Women's Hosp, Boston, MA

4:30 PM

Board # 3088

Using Machine Learning to Identify Sub-Phenotypes of Cardiovascular Disease for Genetic Association

**Juan Zhao** , Vanderbilt Univ VUMC, Nashville, TN; Yun Zhang, Morgan Stanley & Co LLC, New York, NY; Qiping Feng, Vanderbilt Univ Medical, Nashville, TN; Wei-qi Wei, Vanderbilt Univ Medical Ctr, Nashville, TN

4:30 PM

Board # 3089

Associations Between Plasma Talin-1 Levels and the Presence and Severity of Coronary Artery Disease

Masayuki Aoyama, Tokyo Medical Ctr, Tokyo, Japan; Yoshimi Kishimoto, Emi Saita, Ochanomizu Univ, Tokyo, Japan; Yukinori Ikegami, Tokyo Medical Ctr, Tokyo, Japan; Kazuo Kondo, Ochanomizu Univ, Tokyo, Japan; Masato Nakamura, Toho Univ Ohashi Medical Ctr, Tokyo, Japan; **Yukihiko Momiyama** , Tokyo Medical Ctr, Tokyo, Japan

4:30 PM

Board # 3090

**Genotype-First Analysis of** TTR **Variant Carriers Identifies Novel Traits Associated With Heritable Amyloidosis**

**Amy Rosen Kontorovich** , Alexandra McClellan, Sinead Cullina, Gillian Belbin, Peter Gorevic, Eimear Kenny, Noura Abul-Husn, Mount Sinai Sch of Med, New York, NY

4:30 PM

Board # 3091

Gender Differences in Metabolomic Profiles Associated With Incident Coronary Heart Disease in African Americans: The Jackson Heart Study

**Daniel E Cruz** , Bennet Peterson, BIDMC, Boston, MA; Debby Ngo, Beth Israel Deaconess, Boston, MA; Mark Benson, Beth Israel Deaconess Medical Cente, Boston, MA; Zsu Zsu Chen, Usman Tahir, BIDMC, Boston, MA; Yan Gao, Jackson, MS; Thomas J Wang, Clary Clish, Vanderbilt Univ Medical Cente, Nashville, TN; Adolfo Correa, U of Mississippi Medical Ctr, Jackson, MS; James Wilson, Univ of Mississippi Medical C, Jackson, MS; Robert E Gerszten, Beth Israel Deaconess Medical Cente, Boston, MA

# Abstract Poster Session

## AC.APS.03 - Biomarkers III

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 4022

Impact of High Sensitivity Troponin on Hospital Length of Stay and Cardiac Testing in Patients Presenting With Chest Pain: A Retrospective Cohort Study

**Allison Bigeh** , Judd Payne, Sumit Agarwal, Paul Kang, Univ of Arizona Coll of Med, Phoenix, AZ; Joseph S Alpert, The Univ of AZ Coll of Med, Tucson, AZ; Jennifer G Robinson, The Univ of Iowa-Carver Coll of Med, Iowa City, IA; Ankur Mishra, Univ of Arizona Coll of Med, Phoenix, AZ

4:30 PM

Board # 4024

Combined Assessment of Urinary Liver-type Fatty-acid Binding Protein and Plasma B-type Natriuretic Peptide Improves Prediction of Long-term Outcomes in Patients Treated at Medical Cardiac Intensive Care Units

**Hiroyuki Naruse** , Junichi Ishii, Hideto Nishimura, Hideki Kawai, Takashi Muramatsu, Masahide Harada, Akira Yamada, Sadako Motoyama, Fujita Health Univ, Toyoake, Japan; Mutsuharu Hayashi, Banbunntane Houtokukai Hosp, Nagoya, Japan; Masayoshi Sarai, Eiichi Watanabe, Fujita Health Univ, Toyoake, Japan; Hideo Izawa, Banbunntane Houtokukai Hosp, Nagoya, Japan; Yukio Ozaki, Fujita Health Univ, Toyoake, Japan

4:30 PM

Board # 4025

Serum Soluble Tumor Necrosis Factor Receptor (sTNFR) 1 and 2 in STEMI

**Thomas Bochaton** , Hop Louis Pradel, Lyon, France; Alexandre Paccalet, Claire Crola Da Silva, Inserm U1060, Bron, France; Laura Mechtouff, Hop Neurologique, Lyon, France; Delphine Baetz, Inserm U1060, Bron, France; Claire Jossan, Camille Amaz, Guillaume Fiard, Hospices Civils de Lyon, Bron, France; Régine Cartier, Hop Louis Pradel, Bron, France; Danka Tomasevic, Cyril Prieur, Nathalie Genot, Hugo Bernelin, Hop Louis Pradel, Lyon, France; Gilles Rioufol, Cardiovascular Hosp, Lyon, France; Eric Bonnefoy-Cudraz, Hop Louis Pradel, Bron, France; Nathan Mewton, Hop Cardiovasculaire L. Pradel, Bron, France; Michel Ovize, Hospices Civils de Lyon, Lyon, France

4:30 PM

Board # 4026

The Combination of Increased Non-Apoptotic and Decreased Apoptotic Circulating Endothelial Microparticles is Associated With Improved Prognosis in Patients With Acute Coronary Syndromes

**Effimia Zacharia** , Natl and Kapodistrian Univ of Athens Medical Sch, Hippokration Hosp, Athens, Greece; Nikolaos Papageorgiou, Barts Heart Ctr, St. Bartholomew's Hosp, London, United Kingdom, London, United Kingdom; Alexios S Antonopoulos, Univ of Oxford, Oxford, United Kingdom; Evangelos Oikonomou, Zoi Pallantza, Antigoni Miliou, Natl and Kapodistrian Univ of Athens Medical Sch, Hippokration Hosp, Athens, Greece; Anastasios Kriebardis, Technological and Educational Inst of Athens, Athens, Greece; Orologas Nikolaos, Eftychia Valasiadi, Hippokration Hosp, Athens, Greece; Dimitrios Tousoulis, Natl and Kapodistrian Univ of Athens, Medical Sch, Hippokration Hosp of Athens, Athens, Greece

4:30 PM

Board # 4027

Increase in Long-Term Major Adverse Cardiovascular Events in Patients "Appropriately" Tested for Troponin Assays in the Emergency Department

**Ahmed H Qavi** , Prakash Acharya, Fariha Ilyas, Andreea-Constanta Stan, Olvas Dallaku, Stephen Jesmajian, Bernard Gitler, Albert Einstein Coll of Med, Montefiore Medical Ctr, New Rochelle, NY

4:30 PM

Board # 4028

A Hybrid Artificial Intelligence-Intrinsic Frequency Method for Instantaneous Detection of Acute Myocardial Infarction

**Rashid Alavi** , Univ of Southern California, Los Angeles, CA; Wangde Dai, Huntington Medical Res Institu, Pasadena, CA; Robert A Kloner, Huntington Medical Res Inst., Pasadena, CA; Niema M Pahlevan, Univ of Southern California, Los Angeles, CA

4:30 PM

Board # 4029

Serum Bilirubin: A Novel Indicator of Plaque Rupture in Acute Coronary Syndrome

**Michiaki Nagai** , Yusuke Kobayashi, Hiroshima City Asa Hosp, Hiroshima, Japan; Keigo Dote, Hiroshima, Hiroshima, Japan; Masaya Kato, Oda Noboru, Eiji Kunita, Eisuke Kagawa, Aya Yamane, Haruko Shiota, Hiroshi Kobatake, Makoto Takeuchi, Hiroshima City Asa Hosp, Hiroshima, Japan

4:30 PM

Board # 4030

The Ratio Serum Creatinine/Serum Cystatin C as a Predictor of Ischemic Risk in Elderly Patients With Coronary Artery Disease

Hak Seung Lee, You Jeong Ki, Seoul Natl Univ Hosp, Seoul, Korea, Republic of; Jeehoon Kang, Seoul Natl Univ, Seoul, Korea, Republic of; Jung-Kyu Han, Han-Mo Yang, Han-Mo Yang, **Kyung Woo Park** , Hyun-Jae Kang, Seoul Natl Univ Hosp, Seoul, Korea, Republic of; Bon-Kwon Koo, Stanford Univiersity, Stanford, CA

4:30 PM

Board # 4031

Unbiased Discovery Proteomics Approach Using Mass Spectrometry in Search of Peripheral Biomarkers in Patients With Ischemia From Coronary Microvascular Dysfunction

**Armin Nowroozpoor** , Basmah Safdar, Yale Univ Sch of Med, New Haven, CT; David D Gutterman, Medical Coll Wisconsin, Milwaukee, WI

# Abstract Poster Session

## HF.APS.05 - Call in a Surgeon

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2095

Trends in the Coronary Revascularization in Heart Failure With Reduced Ejection Fraction: A Ten Years Analysis From National Inpatient Sample From 2007 to 2016

**Lingling Wu** , Mount Sinai St Luke's and West Hosp, New York, NY; Yingying Zheng, The Brody Sch of Med at East Carolina, Greenville, NC; Faris I Haddadin, Claire Huang Lucas, Kirtipal Bhatia, Bing Yue, Hassan Beydoun, Mount Sinai St Luke's and West Hosp, New York, NY; Bharat Narasimhan, Mount Sinai St Luke's and West Hosp, New york, NY; Xin Wei, Kam Ho, Mount Sinai St Luke's and West Hosp, New York, NY; Pengyang Li, Saint Vincent Hosp, Worcester, MA; Eyal Herzog, Mount Sinai St Luke's and West Hosp, New York, NY

4:30 PM

Board # 2096

Longitudinal Impact of Left Ventricular Assist Devices on Mild Cognitive Dysfunction

**Kenneth M Faulkner** , Boston Coll Stony Brook Univ, Rocky Point, NY; Christopher Chien, UNC Rex, Raleigh, NC; Quin E Denfeld, Oregon Health Science Univ, Portland, OR; Jill M Gelow, Providence Health, Portland, OR; Karen Lyons, Boston Coll, Chestnut Hill, MA; Kathleen L Grady, Northwestern Univ, Chicago, IL; James Mudd, Providence Ctr for Advanced Heart Disease & Transplant, Spokane, WA; Christopher S Lee, Boston Coll William F. Connell Sch of Nursing, Chestnut Hill, MA

4:30 PM

Board # 2097

Stroke Following Current Generation Ventricular Assist Devices: A Systematic Review of Incidence and Outcomes

**Ashley Y Choi** , Duke Univ Sch of Med, Durham, NC; Zachary Brown, Univ of North Carolina SOM, Durham, NC; Yuting Chiang, Michael S Mulvihill, Benjamin Bryner, Jacob N Schroder, Joseph G Rogers, Carmelo A Milano, Muath Bishawi, Duke Univ Medical Ctr, Durham, NC

4:30 PM

Board # 2098

Heart Failure is Associated With Increased All-Cause Mortality In Patients Undergoing Non-Cardiac Surgery

**Darcy Banco** , Nathaniel Smilowitz, New York Univ Sch of Med, New York City, NY; Joshua Beckman, Vanderbilt Univ Sch of Med, Nashville, TN; Jeffrey Berger, New York Univ Sch of Med, New York City, NY

4:30 PM

Board # 2099

Improvement of Left Ventricular Ejection Fraction and Mortality in the Surgical Treatment for Ischemic Heart Failure (STICH) Trial

**Andrew Perry** , Washington Univ in St Louis, Saint Louis, MO; Aldi T Kraja, Cardiovascular Div, Saint Louis, MO; Douglas L Mann, Washington Univ Sch Medicin, St Louis, MO; David L. Brown, Washington Univ, Saint Louis, MO

4:30 PM

Board # 2100

Risk Factors Associated With New-Onset Heart Failure in Patients Undergoing Orthopedic Surgery

**Alexandra M Sanchez** , Univ of Miami Miller Sch of Med, Ft Lauderdale, FL; Rushabh M. Vakharia, Holy Cross Hosp, Ft Lauderdale, FL; Matthew R. Lozier, Univ of Miami Miller Sch of Med, Ft Lauderdale, FL; Martin W. Roche, Holy Cross Hosp, Ft Lauderdale, FL; Joshua Larned, Jim Moran Heart and Vascular Ctr at Holy Cross Hosp, Ft Lauderdale, FL

4:30 PM

Board # 2101

Clinician Opinions About Destination Therapy Left Ventricular Assist Device Assessed Through Hypothetical Self Application: A National Survey

**Larry A Allen** , Univ Colorado Denver, Aurora, CO; Colleen K McIlvennan, Univ Colorado, Denver, CO; Jocelyn S Thompson, Univ Colorado, Sacramento, CA; Monica Edwards, Univ of Colorado SOM, Aurora, CO; Russell Glasgow, Univ of Colorado Anschutz Medical Campus, Aurora, CO; Megan Morris, Univ of Colorado Anschutz Med, Aurora, CO; Matthew K Wynia, Univ Colorado Denver, Aurora, CO; Bridget Mosley, Univ Colorado- Med, Aurora, CO; Dan D Matlock, Univ Colorado, Aurora, CO

# Abstract Poster Session

## EA.APS.06 - Cardiac Implantable Electrical Device Management

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2026

Outcomes Of Laser Lead Extraction In Patients With Structural Congenital Heart Disease: A Single-center Experience

**Harris U Onugha** , Adryan Perez, Darren Tsang, Univ of Miami Miller Sch of Med, Miami, FL; Roger G Carrillo, Palmetto General Hosp, Hialeah, FL

4:30 PM

Board # 2027

Long Term Outcome of Transfemoral Device Implantation: Success Rate, Pitfalls and Complications

**Pooneh Nabavizadeh** , Univ of Cincinnati, Cincinnati, OH; Mehran Attari, Mercy Heart Inst, Cincinnati, OH; Faisal F Syed, Univ of North Carolina, Chapel Hill, NC; Jitender Munjal, Univ Hosp, Cincinnati, OH; Reza Mehzad, Mercy Heart Inst, Fairfield, OH; Srinivas Rajsheker, Univ of Cincinnati, Cincinnati, OH

4:30 PM

Board # 2028

The Long-term Mortality and Severe Complication Rate Are Similar in Patients 85 Years Old or Over and Younger Patients

**Yasuhiro Matsuda** , Masaharu Masuda, Mitsutoshi Asai, Osamu Iida, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takashi Kanda, Takuya Tsujimura, Shota Okuno, Hiroyuki Uematsu, Yuki Sato, Shodai Kawanami, Hiroki Sugae, Sho Nakao, Toshiaki Mano, Kansai Rosai Hosp, Amagasaki, Japan

4:30 PM

Board # 2029

Complete Atrioventricular Block Following Surgical Valve Replacement: Are Patients Still Paced at 1 Year Follow-Up

**Charles Laurin** , Frederic Jacques, Laval Univ, Quebec, QC, Canada; Christian Steinberg, Quebec Heart and Lungs Inst, Quebec, QC, Canada; Jean Champagne, Laval Hosp, Sainte-Foy (Que, QC, Canada; Dimitri Kalavrouziotis, Laval Univ, Quebec, QC, Canada; Francois Philippon, Quebec Heart and Lung Inst, Quebec, QC, Canada

4:30 PM

Board # 2030

Alternative Venous Access Site for Leadless Pacemaker Implantation

**Ivan Mendoza** , Jackson Memorial Hosp, Miami, FL; Rachel Volke, George Washington Hosp, Pasadena, MD; Juan P Zambrano, Ninoska Aranguibel, Jackson Memorial Hosp, Miami, FL; Ivan Mendoza Sr., Tropical Cardiology, Caracas, Venezuela, Bolivarian Republic of

4:30 PM

Board # 2031

Non-Ambulatory Status Predicts the Long-Term Poor Life Prognosis After Cardiac Implantable Electric Device Implantation

**Hiroyuki Uematsu** , Kansai Rosai Hosp, Amagasaki, Japan; Yasuhiro Matsuda, Kansai Rosai Hosp Cardiovascular Ctr, Amagasaki, Japan; Masaharu Masuda, Osaka Univ Hosp, Osaka, Japan; Mitsutoshi Asai, Osamu Iida, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Kansai Rosai Hosp, Amagasaki, Japan; Takashi Kanda, Kansai Rosai Hosp, Amagasaki Hyogo, Japan; Takuya Tsujmura, Shota Okuno, Yosuke Hata, Yuki Sato, Sugae Hiroki, Kawanami Shota, Nakao Sho, Kansai Rosai Hosp, Amagasaki, Japan; Toshiaki Mano, Kansai Rosai Hosp, Suita, Japan

4:30 PM

Board # 2032

Asynchronous Ventricular Pacing in Patients With Normal QRS Duration and Ventricular Function: Implications for Leadless Pacemakers

**Zak Loring** , Rebecca North, Duke Univ Medical Ctr, Durham, NC; Anne Hellkamp, Duke Clinical Res Inst, Bothell, WA; Gervasio A Lamas, Mount Sinai Medical Ctr, Miami Beach, FL; Jonathan P Piccini, Duke Univ Medical Ctr, Durham, NC

4:30 PM

Board # 2033

Risk Factors For Defibrillation Testing Failure In Patients With Transvenous Implantable Cardioverter Defibrillator

**Makoto Nakano** , Kentaro Aizawa, Tohoku Univ Grad Sch of Med, Sendai, Japan; Yuhi Hasebe, Tohoku Univ Hosp, Miyagi, Japan; Susumu Morosawa, Tohoku Univ, Sendai-shi Miyagi, Japan; Hideka Hayashi, Tohoku Univ Grad Sch of Med, Sendai, Japan; Hiroaki Shimokawa, Tohoku Univ Grad Sch Med, Sendai City, Japan

4:30 PM

Board # 2034

Implantable Loop Recorder as a Strategy Following Cardiovascular Implantable Electronic Device Extraction Without Reimplantation

**Michael Eskander** , Travis Pollema, UC San Diego Health, La Jolla, CA; Victor Pretorius, Univ of California-San Diego, La Jolla, CA; Ulrika Birgersdotter-green, Univer of California, San Diego, La Jolla, CA

4:30 PM

Board # 2035

Early vs Late Permanent Pacemaker Implantation After Transcatheter Aortic Valve Replacement: A Single Center Experience

**Kinan Kassar** , Mark Doyle, Stephen Bailey, Ramzi Khalil, Allegheny General Hosp, Pittsburgh, PA

4:30 PM

Poster Professor

Bruce L Wilkoff, Chagrin Falls, OH

# Abstract Poster Session

## IN.APS.04 - Catheter Based Therapies: A Glimpse into the Future

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 4265

Incidence of Atrial Fibrillation on Holter Monitoring After Percutaneous Patent Foramen Ovale Closure in a Prospective Study

**Xavier Odorico** , Jean Christophe Macia, Arnaud de Villeneuve, Univ Hosp, Montpellier, France; Guillaume Cayla, Nimes Univ Hosp, Nimes, France; Florence Leclercq, Arnaud de Villeneuve, Univ Hosp, Montpellier, France

4:30 PM

Board # 4271

A Comparison Study Of Different Approaches Of Left Atrial Appendage Closure: Insights From United States 2016 National Inpatient Sample Database

**Lingling Wu** , Mount Sinai St Luke's and West Hosp, New York, NY; Bharat Narasimhan, Mount Sinai St Luke's and West Hosp, New york, NY; Yingying Zheng, The Brody Sch of Med at East Carolina, Greenville, NC; FARIS I HADDADIN, Mount Sinai St Luke's and West Hosp, New York, NY; Wojciech Rzechorzek, Mount Sinai St Luke's and West Hosp, Chapel Hill, NC; Kirtipal Bhatia, Xin Wei, Bing Yue, Claire Huang Lucas, Kam Ho, Hassan Beydoun, Mount Sinai St Luke's and West Hosp, New York, NY; Ashish Correa, MOUNT SINAI ST LUKES-WEST HOSPITAL, New York, NY; Davendra Mehta, Mount Sinai St Luke's and West Hosp, New York, NY

4:30 PM

Board # 4269

Preprocedural Decompensated Heart Failure Deteriorates Clinical Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement

**Yasuhiro Uchida** , Yokkaichi Municipal Hospita, Yokkaichi, Japan; Hideki Ishii, Nagoya Univ, Nagoya, Japan; Jun Yonekawa, Akinori Satake, Yuichiro Makino, Yokkaichi Municipal Hosp, Yokkaichi, Japan; Wataru Suzuki, Yokkaichi Municipal Hospita, Yokkaichi, Japan; Masanari Kurobe, Koji Mizutani, Yoshiaki Mizutani, Hitoshi Ichimiya, Akinori Tamenishi, Junji Watanabe, Yokkaichi Municipal Hosp, Yokkaichi, Japan; Tetsuya Amano, Aichi Medical Univ, Nagakute, Japan; Masaaki Kanashiro, Yokkaichi Municipal Hosp, Yokkaichi, Japan; Tatsuaki Matsubara, Sch of Dentistry Aichi Gakuin Univ, Nagoya, Japan; Satoshi Ichimiya, Yokkaichi Municipal Hosp, Yokkaichi, Japan; Toyoaki Murohara, Cardiology, Nagoya Univ, Nagoya, Japan

4:30 PM

Board # 4263

Impact of Diabetes Mellitus on Outcomes After Transcatheter Mitral Valve Repair

**Kranthi K Sitammagari** , Atrium Health, Monroe, NC; Kishorbhai Gangani, Texas Health Arlington Memorial, Arlington, TX; Sameer Arora, Univ of North Carolina, Chapel Hill, NC; Bharat Reddy Dhanireddy, Univ of Arkansas for Medical Sciences, Little Rock, AR; Venkata S Dontaraju, Javon Bea Hosp, Rockford, IL; Pedro A Villablanca, Henry Ford Hosp, Detroit, MI

4:30 PM

Board # 4267

Hospital Outcomes of Mitraclip Placement in Teaching versus Non-Teaching Hospitals: Insights From the National Inpatient Sample

**Adebayo C Atanda** , Talal Alzharani, Nardos Temesgen, Jacob Agronin, George Washington Univ Hosp, Washington DC, DC; Joseph Krepp, The George Washington Univ, Washington, DC

4:30 PM

Board # 4270

Readmission Rates Associated With Infective Endocarditis After Transcatheter Aortic Valve Replacement

**Karolina Viquez** , Praneeth Kudaravalli, Elizabeth Woods, Univ of Kentucky Coll of Med, Lexington, KY; Nageshwara Gullapalli, Rajkumar Doshi, Univ of Nevada Reno Sch of Med, Reno, NV

4:30 PM

Board # 4268

Transcatheter vs. Surgical Aortic Valve Replacement in U.S. Renal Transplant Patients

**Charles A Herzog** , James B Wetmore, David T Gilbertson, Chronic Disease Res Group/Hennepin Healthcare/Univ. of Minnesota, Minneapolis, MN

4:30 PM

Board # 4272

Clinically Successful Percutaneous Treatment of Platypnea Orthodeoxia Syndrome in Patients With Patent Foramen Ovale

**Gerard Marti Aguasca** , Alvaro Calabuig Goena, Enric Domingo Ribas, Bernat Serra Creus, Imanol Otaegui Irurueta, Vicens Serra Garcia, Neus Bellera Gotarda, Bruno Garcia del Blanco, Ignacio Ferreira Gonzalez, Hosp Univri Vall D-Hebron, Barcelona, Spain

4:30 PM

Poster Professor

Dharam Kumbhani, Dallas, TX

# Abstract Poster Session

## EP.APS.05 - Contemporary Patterns in the Management and Outcomes of Cardiovascular Diseases

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 3073

Differential Characteristics Associated With Hospital Admission in Cardiac Patients

**Emeka C Anyanwu** , Rhys Chua, Stephanie Besser, Marynia A Kolak, Elizabeth Tung, James K Liao, Corey E Tabit, Univ of Chicago, Chicago, IL

4:30 PM

Board # 3074

Incidence, Prevalence, and Prognostic Implications of Atrial Fibrillation Among Patients Undergoing Non-Cardiac Surgery

**Anirudh Bhargava** , UAB Sch of Med, Birmingham, AL; Rajat Kalra, Univ of Minnesota, Minneapolis, MN; Nirav Patel, Univ of Alabama at Birmingham, Birmingham, AL; Vibhu Parcha, Univ of Alabama, Birmingham, AL; Garima Arora, Pankaj Arora, Univ of Alabama at Birmingham, Birmingham, AL

4:30 PM

Board # 3075

Cardiovascular Risk Factors and Disease Are Associated With Long-Term but Not Short-Term Mortality in Patients Undergoing Hematopoietic Stem Cell Transplantation

Daniel A Perry, **Christopher W Hoeger** , Radhika Takiar, Pennelope Kunkle, Monika Leja, Salim S Hayek, Univ of Michigan, Ann Arbor, MI

4:30 PM

Board # 3076

Outcomes of Hospitalizations With Acute Myocardial Infarction and Spontaneous Coronary Artery Dissection: A Population-Based Study

**Mohamed M Gad** , Cleveland Clinic, Cleveland, OH; Ahmed N Mahmoud, Univ of Washington, Seattle, WA; Anas Saad, Cleveland Clinic Fndn, Cleveland, OH; Najdat Bazarbashi, Univ of Maryland, Baltimore, MD; Keerat Rai Ahuja, Cleveland Clinic Fndn, Beachwood, OH; Antonette Karrthik, Univ of Washington, Cleveland, OH; Islam Y Elgendy, Massachusetts General Hosp, Boston, MA; Akram Elgendy, Michael R Massoomi, Univ of Florida, Gainesville, FL; Jacqueline Saw, Vancouver General Hosp, Vancouver, BC, Canada; R. David Anderson, Univ of Florida, Gainesville, FL; Samir R Kapadia, Cleveland Clinic, Cleveland, OH

4:30 PM

Board # 3077

Trends, Outcomes and Predictors of Utilization of Electrical Cardioversion in Patients Hospitalized for Atrial Fibrillation: Nis Database 2005-2014

**Harshil Shah** , Shantanu Solanki, Guthrie Robert Packer Hosp, Sayre, PA; Achint Patel, Univ of Arkansas for Medical Sciences, Little Rock, AR; Hee Kong Fong, Univ of Missouri - Columbia, Columbia, MO; Edo None Kaluski, Robert Packer Hosp, Sayre, PA

4:30 PM

Board # 3078

Incidence, Predictors, and Prognostic Impact of Bleeding After Hospital Discharge Following Acute Coronary Syndrome: A Cohort Study Within the Clinical Practice Research Datalink

**Nafiu Ismail** , Kelvin P Jordan, Keele Univ, Staffordshire, United Kingdom; Umesh T Kadam, Univ of Leicester, Leicester, United Kingdom; John J Edwards, Mamas Andreas Mamas, Keele Univ, Staffordshire, United Kingdom

4:30 PM

Board # 3079

Epidemiological Trends in Hospitalizations of Patients With Marfan Syndrome From 2001 Through 2016

**Ala Mohsen** , John Conner, Louisiana State Univ, New Orleans, LA; Alhuneafat Laith, Univ of Pittsburgh Medical Ctr, Hermitage, PA; Ahmed M Altibi, Henry Ford Allegiance Health, Jackson, MI; Ahmad Masri, Univ of Pittsburgh, Pittsburgh, PA

4:30 PM

Board # 3080

Baseline Characteristics, Management, and Outcomes of Patients With Infective Endocarditis

**Wojciech Rzechorzek** , Guneesh Uberoi, Mount Sinai St. Luke's West, New York, NY; kirtipal Bhatia, Mount Sinai St Luke's-West, New York City; Ruchit Shah, Ichan Sch of Med Mt. Sinai, New York, NY; Lingling Wu, Mount Sinai St Luke's and West, New York, NY; Robert J Kornberg, Mount Sinai Heart, New York, NY

4:30 PM

Board # 3081

Telemedicine to Guide AMI Management - Introducing a New Metric for Evaluating Efficiency

**Sameer Mehta** , Roberto Botelho, Jamil Cade, Marco Perin, Mauricio Prudente, Ricardo Cavalcanti, Rodolfo Cardoso, Freddy Bojanini, Nabil Hamdan, Cesar Dusilek, Marco Alcocer, Juan Carlos Perez Alva, Lumen Fndn, Miami, FL; Alfredo Estrada, Medica Diamante., Tuxtla Gutierrez, Chiapas, Mexico; Manuel Odin De Los Rios, Alejandra Frauenfelder, Daniel Vieira, Mariana Ceschim, Gladys Pinto, Samantha Quintero, Francisco Nola, Maria I Acosta, Claudia Lopez, Seyna Krisciunas, Jose S Aguilar, Lilly Prieto, Akhil Vaid, Lumen Fndn, Miami, FL

4:30 PM

Board # 3082

Electronic Medical Record-Based Machine Learning Approach to Predict the Risk of 30-Day Major Adverse Cardiac Event After Invasive Coronary Treatment

**Osung Kwon** , Catholic Univ of Korea, Eunpyeong St. Mary's Hosp, Seoul, Korea, Republic of; Wonjun Na, Hyeonkyeong Yang, Jihoon Kweon, Dong Hyun Yang, Asan Medical Ctr, Univ of Ulsan Coll of Med, Seoul, Korea, Republic of; Jungwoo Chae, Cinyoung Hur, Yonghyun Cho, Linewalks Inc., Seoul, Korea, Republic of; Young-Hak Kim, Asan Medical Ctr, Seoul

# Abstract Poster Session

## IM.APS.05 - CT: Heart and Vessels

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 4186

A Novel 3-dimentional Technique in Measuring Pericoronary Epicardial Adipose Tissue Radiodensity and Association With Coronary Artery Disease

**Lingyu Xu** , Stanislau Stanislau, Univ of Alberta, Edmonton, AB, Canada; Yuancheng Xu, The Third Hosp of Sun Yat-Sen Univ, Guangzhou, China; Richard Coulden, Emer Sonnex, Ian Paterson, Butler Craig, Univ of Alberta, Edmonton, AB, Canada

4:30 PM

Board # 4187

Coronary Perivascular Fat Attenuation Index in Heterozygous Familial Hypercholesterolemia

**Marcio Hiroshi Miname** , Heart Inst (InCor), Sao Paulo, Brazil; Andrea M Giovannini Bercht, Heart Inst, Sao Paulo, Brazil; Thamara Morais, Heart Inst (InCor), Sao Paulo, Brazil; Antonildes Assuncao-Jr, Hear Inst - InCor, São Paulo, Brazil; Raul D Santos, Incor- Univ. of Sao Paulo, Sao Paulo, Brazil; Cesar Higa Nomura, InCor-SP (Heart Inst), Sao Paulo - Sp, Brazil

4:30 PM

Board # 4188

Simultaneous Cardiac Computed Tomography for Both Coronary Artery Status and Myocardial Fibrosis Showed High Concordance Rate of Etiology Determination on Patients With Newly Diagnosed Heart Failure

**Jong-Chan Youn** , Seoul St. Mary's Hosp, The Catholic Univ of Korea, Seoul, Korea, Republic of; Jin-jin Kim, Seoul St. Mary Hosp, The Catholic Univ of Korea, Seoul, Korea, Republic of

4:30 PM

Board # 4189

Non-Invasive Calculation of Local Coronary Endothelial Shear Stress: Head-to-head Comparison of Ccta-Derived vs Ivus-Derived Intracoronary Imaging Using Computational Fluid Dynamics (cfd)

**Ahmet U Coskun** , Northeastern Univ, Boston, MA; Gerasimos Siasos, Univ of Athens Medical Sch, Athens, Halandri, Greece; Nicholas Cefalo, Brigham & Women's Hosp, Boston, MA; Marina Zaromytidou, Univ of Athens Medical Sch, Kastoria, Greece; Michelle A Cormier, Brigham & Women's Hosp, Boston, MA; Arnav Kumar, Emory Univ Sch of Med, Atlanta, GA; Molony David, Hossein Hosseini, Emory Univeristy Medical Sch, Atlanta, GA; Kevin J Croce, Anubodh Varshney, Brigham & Women's Hosp, Boston, MA; James K Min, Weill Cornell Medical Coll, New York, NY; Habib Samady, Emory Univeristy Medical Sch, Atlanta, GA; Peter H Stone, Brigham & Women's Hosp, Boston, MA

4:30 PM

Board # 4192

Bayesian Analysis to Harmonize Discordant Coronary CT Angiography With Coronary CT Fractional Flow Reserve Results

**Timothy F Christian** , Simcha Pollack, Jane Cao, St Francis Hosp, Greenvale, NY

4:30 PM

Board # 4193

Inconclusive CT Angiography Test Results Are Less Frequent but Lead to More Testing and Have Higher 24-Month Medical Costs in Stable Patients With Suspected Coronary Artery Disease: Insights From the PROMISE Trial

**Akash Goyal** , Neha Pagidipati, Daniel B Mark, Duke Univ Medical Ctr, Durham, NC; Larry Hill, Duke Clinical Res Inst, Durham, NC; Brooke Alhanti, Duke Univ, Durham, NC; James E Udelson, Tufts Med Ctr, Boston, MA; Michael Picard, Massachusetts General Hosp, Boston, MA; Patricia A Pellikka, Mayo Clinic Coll Med, Rochester, MN; Udo Hoffmann, Massachusetts General Hosp, Boston, MA; Pamela S Douglas, Duke Univ DUMC, Durham, NC

4:30 PM

Board # 4194

Multimodality Image Approach to Evaluate the Delivery and Impact of a Novel Imageable Hydrogel Post Myocardial Infarction

**Ricardo Avendano** , Yale Univ Sch of Med, New Haven, CT; Dan Midgett, Shin Rong Lee, Stephanie Thorn, Yale Univ, New Haven, CT; Christi Hawley, Marina Mamarian, Yale Univ Sch of Med, New Haven, CT; Selen Uman, Univ of Pennsylvania, Philadelphia, PA; Jay Dowell Humphrey, James Duncan, Yale Univ, New Haven, CT; Jason A Burdick, Univ of Pennsylvania, Philadelphia, PA; Albert J Sinusas, Yale Univ Sch Med, New Haven, CT

4:30 PM

Board # 4195

Left Atrial Calcification on Cardiac Computed Tomography and Rhythm Outcome in Patient Underwent Mitral Valve Surgery

Chi Young Shim, **Shinjeong Song** , Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Jah Yeon Choi, Korea Univ Guro Hosp, Seoul; Young-Ju Seo, Young Jin Kim, Ji Won Seo, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Geu-Ru Hong, Yonsei Univ, Seoul; Jong-Won Ha, Yonsei Univ Coll of Med, Seoul

4:30 PM

Poster Professor

Melissa A Daubert, Durham, NC

4:30 PM

Board # 4196

Dynamic Solid State SPECT Evaluation of Myocardial Blood Flow in Hemodialysis Patients

**Ricardo A Nieves** , Joseph Dietz, Prem Soman, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA

4:30 PM

Board # 4197

Heterogeneity of Electron Density in Aortic Valve Calcification of Aortic Stenosis Based on Dual-Source, Dual-Energy Computed Tomography

**Mitsuru Kanisawa** , Nobuo Iguchi, Sakakibara Heart Inst, Tokyo, Japan; Haruhiko Machida, Kyorin Univertsity, Tokyo, Japan; Kenichi Hagiya, Ryosuke Higuchi, Mike Saji, Itaru Takamisawa, Mamoru Nanasato, Kaori Takada, Yoshiyuki Mizutani, Mitsuaki Isobe, Sakakibara Heart Inst, Tokyo, Japan

4:30 PM

Board # 4198

The Absence of Perfusion Defect on Contrast Enhanced Chest CT Prior to Coronary Angiography May Exclude Ischemic Etiology for Survivors of Sudden Cardiac Arrest

**Yassar Nabeel** , Case Western Reserve Univ / Metrohealth Medical Ctr, Cleveland, OH; Ahmad Jabri, Cleveland Clinic Akron General, Akron, OH; Muhammad Butt, William Baughman, Jonathan Glaab, Joseph Sudano, Metrohealth Medical Ctr, Cleveland, OH; Ashish Aneja, Case Western Reserve Univ / Metrohealth Medical Ctr, Cleveland, OH

4:30 PM

Board # 4199

Association of Aortic Stiffness With Subclinical Left Ventricular Remodeling in African Americans

**Inbar Raber** , Beth Israel Deaconess Medical Ctr, Boston, MA; Floyd F. Washington, Solomon K Musani, Univ of Mississippi Med Ctr, Jackson, MS; James G Terry, Vanderbilt Univ Medical Ctr, Nashville, TN; Adebamike Adedayo Oshunbade, Univ of Mississippi Medical C, Jackson, MS; William G Hundley, Wake Forest Univ Medical Sch, Winston Salem, NC; Gary F Mitchell, Cardiovascular Engineering, Inc, Norwood, MA; Ervin R Fox, Univ of Mississippi Med Ctr, Jackson, MS; Connie W Tsao, Beth Israel Deaconess Medical Ctr, Boston, MA

# Abstract Poster Session

## HF.APS.08 - Devices and Medications: Improving HF care

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2124

**Pharmacokinetics and Tolerability of KNO** 3 **in Patients With Heart Failure With Reduced Ejection Fraction**

**Linda Peterson** , Washington Univ, St. Louis, MO; Susan Beth Racette, Washington Univ Sch of Med, Saint Louis, MO; William T Cade, Dakkota Thies, Washington Univ, St. Louis, MO; Ken Schechtman, Washington Univ, Saint Louis, MO; D A Gray, Andrew R Coggan, Indiana Univ Purdue Univ, Indianapolis, IN

4:30 PM

Board # 2125

Observational Report of The Prognostic Impact of Landiolol in Acute Heart Failure Patients Presenting Atrial Fibrillation With Rapid Ventricular Response

**Shota Shirotani** , Kentaro Jujo, Takuro Abe, Motoko Kametani, Yuichiro Minami, Atsushi Suzuki, Tsuyoshi Shiga, Nobuhisa Hagiwara, Tokyo Women's Medical Univ, Tokyo, Japan

4:30 PM

Board # 2126

Empagliflozin versus Canagliflozin for Prevention of Heart Failure in Patients With Type Two Diabetes

**Joseph Azuri** , Tel Aviv Univ, Tel Aviv, Israel; Ariel Hammerman, Clalit Health Services, Tel Aviv, Israel; Enis Aboalhasan, Ronen Arbel, Sapir Coll, Sderot, Israel

4:30 PM

Board # 2127

The Effect of Beta Blockers on Maintaining Quality of Life at One Year After Discharge in Patients With Heart Failure With Preserved Ejection Fraction - From the Pursuit Hfpef Registry

**Takayuki Kojima** , Shungo Hikoso, Osaka Univ Graduate Sch of Med, Suita, Japan; Yoshio Yasumura, Amagasaki Chuo Hosp, Amagasaki, Japan; Takahisa Yamada, Osaka General Medical Ctr, Osaka, Japan; Masaaki Uematsu, Natl Hosp Organization Osaka Natl Hosp, Osaka, Japan; Shunsuke Tamaki, Osaka General Medical Ctr, Osaka, Japan; Yoshiharu Higuchi, Osaka Police Hosp, Osaka, Japan; Yusuke Nakagawa, Kawanishi City Hosp, Kawanishi, Japan; Hisakazu Fuji, Kobe Ekisaikai Hosp, Kobe, Japan; Masami Nishino, Osaka Rosai Hosp, Sakai, Japan; Dsaisaku Nakatani, Tetsuhisa Kitamura, Tomomi Yamada, Hiroya Mizuno, Katsuki Okada, Tomoharu Dohi, Bolrathanak Oeun, Hirota Kida, Akihiro Sunaga, Taiki Sato, Yasushi Sakata, Osaka Univ Graduate Sch of Med, Suita, Japan

4:30 PM

Board # 2128

Comparison of Outcome Adjudication by Investigators and by a Central Endpoint Committee (CEC) in Heart Failure Trials: Experience of the Shift Heart Failure Study

**Benoit TYL** , Servier, Suresnes Cedex, France; José López Sendón, Hosp Univrio La Paz, Madrid, Spain; Jeffrey Stephen Borer, HSCB Fndn Inc, Suny Downstate, New York, NY; Esteban López De Sá, Hosp Univrio La Paz, Madrid, Spain; Guy Lerebours, Claire Varin, Aurélie de Montigny, Servier, Suresnes Cedex, France; Michel Komajda, Ch Pitie Salpetriere, Paris, France

4:30 PM

Board # 2129

Effect of Left Ventricular Assist Device Implantation on Renal Function in Patients With Previous Renal Dysfunction Listed for Heart Transplantation

**Alexis K Okoh** , Ritu Chakrabarti, RWJ Barnabas Health NBIMC, Newark, NJ; Sameer Hirji, Brigham and Women`s Hosp, Boston, MA; Nawar Al Obaidi, RWJ Barnabas Health NBIMC, Newark, NJ; Setri Fugar, Rush Univ Medical Ctr, Chicago, IL; Swaiman Singh, Newark Beth Israel Medical Ctr, Jackson, NJ; Maxwell Afari, RWJ Barnabas, Newark, NJ; Uzo Okoro, Marshall Univ Joan C Edwards, Huntington, NJ; harsh mehta, Saint Barnabas Medical Ctr, Livingston, NJ; Mark Russo, Columbia Univ, New York, NY; Leonard Lee, Rutgers Robert Wood Johnson Medical Sch, New Brunswick, NJ; Margarita Camacho, RWJ Barnabas Health NBIMC, Newark, NJ

4:30 PM

Board # 2130

Cardiac Hemodynamic Parameters & Survival Outcomes of Impella in Refractory Cardiogenic Shock - A Systematic Review and Meta-Analysis

**Tikal Kansara** , Abdullah Zoheb Azhar, Metropolitan Hosp Ctr, New York, NY; Palak Shah, SBKS Medical Inst and Res Ctr, Vadodara, India; Rajkumar Prakashbhai Doshi, Univ of Nevada Reno SOM, Reno, NV; Monil Majmundar, Metropolitan hospital Ctr, New York, NY

4:30 PM

Board # 2131

Chronic Heart Failure: Efficacy of Renal Denervation

**Pedro Aguiar 50** , Insto Medico La Floresta, Caracas, Venezuela, Bolivarian Republic of

4:30 PM

Board # 2132

A Comparison of Hemodynamic Parameter & Mortality Between Temporary Mechanical Circulatory Support & Intra-Aortic Balloon Pump in Refractory Cardiogenic Shock - A Systematic Review and Meta-Analysis

**Monil Majmundar** , Abdullah Zoheb Azhar, Metropolitan Hosp Ctr, New York, NY; Palak Shah, SBKS Medical and Res Ctr, Vadodara, India; Rajkumar Prakashbhai Doshi, Univ of Nevada Reno SOM, Reno, NV; Tikal Kansara, Metropolitan Hosp Ctr, New York, NY

4:30 PM

Board # 2133

A Novel Superior Vena Caval Occlusion Catheter System Reduces Biventricular Filling Pressures While Maintaining Cardiac Output In A Model Of Acute Congestive Heart Failure

**Navin K Kapur** , Tufts Medical Ctr, Hanover, MA; Richard H Karas, Lara Alexis Reyelt, Tufts Medical Ctr, Boston, MA; Tim Lenihan, MDSTART, Paris, France; Daniel Burkhoff, Cardiovascular Res Fndn, New York, NY

4:30 PM

Board # 2134

Endogenous Production of Enos via Whole Body Periodic Acceleration (wbpa) is a Novel Treatment for Duchenne Cardiomyopathy in Mdx Mice

**Jose Antonio Adams** , Mount Sinai Medical Ctr, Miami Beach, FL; Arkady Uryash, Mount Sinai Medical Ctr Res, Miami Beach, FL; Eric Esteve, Univ of California San Diego, La Jolla, CA; Jose R Lopez, Mount Sinai Medical Ctr, Miami Beach, FL

# Abstract Poster Session

## LF.APS.05 - Diet Composition and Outcomes

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 3202

Major Adverse Cardiac Events With Combined Use of Eicosapentaenoic Acid and Statin: A Meta-analysis

**Rajkumar Prakashbhai Doshi** , Univ of Nevada Reno SOM, Reno, NV; Jay Shah, Mercy St. Vincent Medical Ctr, Toledo, OH; Samarthkumar Thakkar, Rochester General Hosp, Rochester, NY; Ashish Kumar, Saint John's Medical Coll Hosp, Bangalore, India; Zahara Meghji, Univ Of Nevada Reno Sch of, Reno, NV; Nageshwara Gullapalli, Univ of Nevada Reno SOM, Reno, NV

4:30 PM

Board # 3204

Higher Carbohydrate Amount and Lower Glycemic Index Increase Hunger, Diet Satisfaction, and Gastrointestinal Symptom of Heartburn: Results From the Omnicarb Randomized Clinical Trial

**Yingfei Wu** , Johns Hopkins Sch of Public Health, Baltimore, MD; Stephen P Juraschek, BIDMC-Harvard Medical Sch, Auburndale, MA; Jiun-Ruey Hu, Vanderbilt Univ Medical Ctr, Nashville, TN; Edgar R Miller, Johns Hopkins Medical Insts, Baltimore, MD

4:30 PM

Board # 3205

The Associations of Weight Cycling With Body Composition, Energy Expenditure, Hunger, and Glycemia in Overweight Adults With Prediabetes and Type 2 Diabetes

**Margaret A Curran** , David E St-Jules, Collin Popp, Paige Illiano, Antoinette Schoenthaler, Mary Ann Sevick, NYU Sch of Med, New York, NY

4:30 PM

Board # 3206

A Systematic Review on the Impact of Food Provision Studies on Heart Disease Outcomes

**Joe B Martinez** , Healthy Meals Supreme, LLC, Princeton, NJ; Aleda M Chen, Julia Gardner, Sarah Berman, Juanita A Draime, Cedarville Univ, Cedarville, OH

4:30 PM

Board # 3207

Replacement of Saturated Fatty Acids With Monounsaturated Fatty Acids From Canola Oils That Vary in MUFA Quantity Does Not Improve Flow Mediated Dilation

**Kristin Davis** , The Pennsylvania State Univ, University Park, PA; Kate Joan Bowen, The Pennsylvania State Univ, University Pk, PA; Carla G Taylor, Peter Zahradka, Univ of Manitoba, Winnipeg, MB, Canada; Karen Letourneau, Danielle Perera, Angela Wilson, St. Boniface Res Hosp, Winnipeg, MB, Canada; Paul R Wagner, The Pennsylvania State Univ, University Park, PA; Penny M Kris-Etherton, Pennsylvania State Univ, University Park, PA; Sheila West, The Pennsylvania State Univ, University Park, PA

4:30 PM

Board # 3208

Associations With Red Meat Consumption Among New York City Residents

**Eric J Brandt** , Yale Univ Sch of Med, New Haven, CT

4:30 PM

Board # 3209

Raphanus Sativus **Cv. Sakurajima Daikon as a Functional Food May Improve Vascular Endothelial Function**

**Takashi Kajiya** , Tenyoukai Central Hosp, Kagoshima, Japan; Maho Sasaki, Kagoshima Univ, Kagoshima, Japan; Yoshihiko Atsuchi, Nobuhiko Atsuchi, Tenyoukai Central Hosp, Kagoshima, Japan; Katsuko Kajiya, Kagoshima Univ, Kagoshima, Japan

# Abstract Poster Session

## HT.APS.02 - Digital Decision Support

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 3143

A Simulation in CAD: Improving Performance of Cardiologists Through Online CME

**Jelena Spyropoulos** , Medscape Education, New York, NY; Caroline Padbury, Medscape, Atlanta, GA

4:30 PM

Board # 3144

Use of an Electronic Decision Support Tool Improves Team Performance During in-situ Simulation of In-hospital Cardiac Arrest

**Rachel S Chang** , Sharon Kam, Santiago Angaramo, Vanderbilt Univ Sch of Med, Nashville, TN; Matthew D McEvoy, Britany Raymond, Vanderbilt Univ Medical Ctr, Nashville, TN

4:30 PM

Board # 3145

Limiting the Number of Open Charts in the Electronic Medical Record Does Not Decrease Order Entry Errors in Cardiovascular Inpatient and Intensive Care Units

Heather Blonksy, Rachel Shirley, Alex Milinovich, Kay Tucker, Allison Weathers, Baruch Fertel, Chiedozie Udeh, Aaron Hamilton, **Antonio L Perez** , Cleveland Clinic, Cleveland, OH

4:30 PM

Board # 3147

Improved Heart Failure Self-Care in a Medicare Population Receiving Virtual Behavioral Therapy: A Health Plan-Provider Collaboration

**Heidi Mochari Greenberger** , AbleTo, New York, NY; Consuela Dennis, Humana, Louisville, KY; Evie Andreopoulos, Naomi Pollock, Aimee Peters, Reena L Pande, AbleTo, New York, NY

4:30 PM

Board # 3148

Heart Pathway Implementation Safely Reduces Hospitalizations at 1-Year in Patients With Acute Chest Pain

Jason P Stopyra, Wake Forest Univ Sch of Med, Winston-Salem, NC; Anna Snavely, Wake Forest Sch of Med, Winston-Salem, NC; Brian J Wells, Wake Forest Univ Sch of Med, Winston-Salem, NC; David M Herrington, Wake Forest Univ Sch Medici, Winston Salem, NC; Brian C Hiestand, Chad D Miller, Wake Forest Univ Sch of Med, Winston-Salem, NC; **Simon A Mahler** , Wake Forest Sch Med, Winston Salem, NC

4:30 PM

Board # 3149

Precision Cardiovascular Medicine: A Rapid and Highly Sensitive Artificial Intelligence-Based Integrated Genetic-Epigenetic DNA Test for 3-Year Risk for Incident Coronary Heart Disease

**Meesha Dogan** , Cardio Diagnostics, Coralville, IA; Stacey Knight, Intermountain Medical Ctr, Salt Lake City, UT; Amaury Lendasse, Univ of Houston, Houston, TX; Kirk Ute Knowlton, Intermountain Medical Ctr, Salt Lake City, UT; Robert Philibert, Univ of Iowa, Iowa City, IA

4:30 PM

Board # 3150

Remote, Integrated Algorithm-based CV Risk Management Program Improves Hypertension and LDL Control

Naomi Dl Fisher, **Jorge Plutzky** , Brigham and Women's Hosp, Boston, MA; Christopher P Cannon, Brigham and Women's Hosp,, Boston, MA; David Zelle, Brigham and Women's Hosp, Boston, MA; Anton B Dodek, Allways Health Partners, Somerville, MA; Calum A MacRae, Benjamin M Scirica, Brigham and Women's Hosp, Boston, MA; Thomas A Gaziano, Brigham Womens Hosp, Boston, MA

4:30 PM

Board # 3151

Developing Convolutional Neural Networks for Deep Learning of Ventricular Action Potentials to Predict Risk for Ventricular Arrhythmias

**Anojan Selvalingam** , Stanford Univ, Stanford, CA; Mahmood Alhusseini, Albert J Rogers, Stanford Univ, Palo Alto, CA; David Edward Krummen, Univ of California, San Diego, San Diego, CA; Firas M Abuzaid, Stanford Univ, Stanford, CA; Junaid A Zaman, Imperial Coll London, London, CA; Tina Baykaner, Stanford Univ, Palo Alto, CA; Paul L Clopton, Stanford Med, Stanford, CA; Peter Bailis, Matei Zaharia, Stanford Univ, Stanford, CA; Sanjiv M Narayan, Stanford Med, Stanford, CA

4:30 PM

Board # 3152

Convolutional Neural Networks for Interpretation of Coronary Angiography

**Paul C Lee** , Stony Brook Heart Inst, Stony Brook, NY; Nathaniel Lee, Stanford Univ, Stanford, CA; Robert Pyo, Stony Brook Heart Inst, Stony Brook, NY

4:30 PM

Poster Professor

Mujeeb Basit, Brookline, MA

# Abstract Poster Session

## HT.APS.04 - Emerging Technologies and Disease Markers

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 3153

A Novel Augmentation Device for Ventilation Utilizing the Bag Valve Mask in EMS and Resource Limited Settings

**Rohith Malya** , Carolina De Santiago, Natalie Dickman, Madison Nasteff, Tim Nonet, Aravind Sundaramraj, Karen Vasquez, Sabia Abidi, Maria Oden, Rice Univ, Houston, TX

4:30 PM

Board # 3154

Using Deep Learning to Predict the Framingham Risk Score From Brain Magnetic Resonance Imaging

**Camilo Bermudez Noguera** , Vanderbilt Univ, Nashville, TN; Lori Held, NIA, NIH, Baltimore, MD; Susan Resnick, Natl Inst of Aging, Baltimore, MD; Quinn Wells, bennett landman, Vanderbilt Univ, Nashville, TN

4:30 PM

Board # 3155

Ensemble Learning Models Provide Expert-Level Prenatal Detection of Complex Congenital Heart Disease

**Rima Arnaout** , Lara Curran, Yili Zhao, UCSF, San Francisco, CA; Jami C Levine, Childrens Hosp, Boston, MA; Erin Chinn, UCSF, San Francisco, CA; Anita Moon-Grady, Univ. of California San Francisco, San Francisco, CA

4:30 PM

Board # 3156

A Deep Learning Model to Predict Outcome After Thoracoscopic Surgery for Atrial Fibrillation Using Single Beat Electrocardiographic Samples

**Sarah WE Baalman** , Lucas A Ramos, Ricardo R Lopes, Willeke Van Der Stuijt, Hidde Bleijendaal, Tom F Brouwer, Henk A Marquering, Antoine HG Driessen, Reinoud E Knops, Joris R. de Groot, Amsterdam UMC, Amsterdam, Netherlands

4:30 PM

Board # 3157

Improving Implanted Device Remote Monitoring Adherence Through Data Sharing

Tammy Toscos, Ryan Ahmed, **Shauna Wagner** , Parkview Health, Fort Wayne, IN; Michael Joseph Mirro, Parkview Health System, Fort Wayne, IN

4:30 PM

Board # 3158

Predictive Ability of Machine Learning Models for High-Grade Coronary Artery Disease Using Free Fatty-Acid Metabolites

**Raymond O McCubrey** , Viet T Le, Intermountain Medical Ctr, Salt Lake City, UT; Jeramie Watrous, Mahan Najhawan, Khoi Dao, Univ of California San Diego, La Jolla, CA; Benjamin D Horne, Jeffrey Lance Anderson, Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT; Kirk Ute Knowlton, Intermountain Medical Ctr, Salt Lake City, UT; Mohit Jain, Univ. of California - San Diego, La Jolla, CA; Stacey Knight, Intermountain Medical Ctr, Murray, UT

4:30 PM

Board # 3159

Tissue to Organ Level Evaluation of Heart Valve Scaffold Performance Under Dynamic Loading Conditions

**Drake Pedersen** , Univ of Pittsburgh, Pittsburgh, PA; Francesco Madonia, Univ of Palermo, Palermo, Italy; Casey Tompkins-Rhoades, Antonio D'Amore, Univ of Pittsburgh, Pittsburgh, PA; William R Wagner, McGowan Inst, Pittsburgh, PA

4:30 PM

Board # 3160

Predicting Cerebrovascular Accident in Patients With Implantable Ventricular Assist Device Using Artificial Intelligence Trained on Acoustic Spectra

**Yusuke Misumi** , Hidetsugu Asanoi, Shigeru Miyagawa, Yasushi Yoshikawa, Hiroki Hata, Daisuke Yoshioka, Satoshi Kainuma, Takuji Kawamura, Ai Kawamura, Yuichi Maruyama, Koichi Toda, Yoshiki Sawa, Osaka Univ, Osaka, Japan

4:30 PM

Board # 3161

Artificial Intelligence to Identify Commonly Asked Questions via an Electronic Patient Portal - Lessons From a Cardiology Department Within a Large Health System

**Jedrek Wosik** , Shijing Si, Ricardo Henao, Lawrence Carin, Duke, Durham, NC; Manesh R Patel, Duke Medical Ctr, Durham, NC

4:30 PM

Board # 3162

An AI Enabled Dynamic Coning System Reduces the Radiation Dose During Fluoroscopy

**Lindsay Machan** , Univ of British Columbia, Vancouver, BC, Canada

4:30 PM

Board # 3163

Podocan, A Wingless-Regulatory Molecule, is Associated With Atrial Fibrillation

**Kanramon Watthanasuntorn** , Nancy Bethuel, Anukrati Shukla, Kanjit Leungsuwan, Maryam Khavandi, Jennifer Victory, Melissa Scribani, Bishesh Shrestha, Bassett Medical Ctr, Cooperstown, NY; Paul Klotman, Deborah Hyink, Baylor Coll of Med, Houston, TX; James Storey, Randolph Hutter, Daniel Katz, Bassett Medical Ctr, Cooperstown, NY

# Abstract Poster Session

## EP.APS.07 - Epidemiology of Acute Cardiovascular Emergencies

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 3093

Sudden Cardiac Death Associated With Sarcoidosis in the General Population

**Audrey Uy-Evanado** , Harpriya Chugh, Kyndaron Reinier, Cedars-Sinai Medical Ctr, Los Angeles, CA; Eric Stecker, Jonathan Jui, Oregon Health and Science Univ, Portland, OR; Sumeet S Chugh, Cedars-Sinai Medical Ctr, Los Angeles, CA

4:30 PM

Board # 3094

Underlying Causes of Sudden Cardiac Arrest in Survivors versus Non-Survivors in the San Francisco POstmortem Systematic InvesTigation of Sudden Cardiac Death (POST SCD) Study

**Santo Ricceri** , UC San Francisco, San Francisco, CA; Andrew A Vu, California Pacific Medical Ctr, San Francisco, CA; Jeffrey Olgin, Philip C Ursell, UC San Francisco, San Francisco, CA; Ellen Moffatt, Office of the Chief Medical Examine, San Francisco, CA; Zian H Tseng, UC San Francisco, San Francisco, CA

4:30 PM

Board # 3095

Predictors Of Inpatient Mortality In Patients With Sudden Cardiac Arrest

**Muhammad Zia Khan** , WV Med, Section of Hosp Me, Morgantown, WV; Muhammad Munir, West Virginia Univ, Sch of Med, Morgantown, WV; Muhammad Usman Khan, West Virginia Univ, HSC, Morgantown, WV; Safi Ullah Khan, West Virginia Univ, Morgantown, WV; Ahmad Naeem Lone, Sudarshan Balla, West Virginia Univ, Sch of Med, Morgantown, WV

4:30 PM

Board # 3096

Difference in Survival Outcomes for Out-of-Hospital Cardiac Arrest After 2010 American Heart Association- Emergency Cardiovascular Care Guidelines for Cardio-Pulmonary Resuscitation

**Anusha Ganapati Bhat** , Baystate Medical Ctr, Springfield, MA; Deepak Kumar Pasupula, Univ of Pittsburgh Medical Ctr, Hermitage, PA; Sudeep Kumar Siddappa Malleshappa, Baystate Medical Ctr, Springfield, MA; Muhammad Bilal Munir, Amr Barakat, Sandeep Jain, Norman Wang, Aditya Bhonsale, Samir Saba, Univ of Pittsburgh Medical Ctr, Hermitage, PA

4:30 PM

Board # 3097

Adherence to Guidelines is Associated With Improved Survival Following In-hospital Cardiac Arrest in Sweden

**Fredrik Hessulf** , Inst of Med, Gothenburg, Sweden; Johan Herlitz, Sahlgrenske Univerty Hosp, Gothenberg, Sweden; Aaraz Rawshani, Inst of Med, Gothenburg, Sweden; Solveig Aune, Unit for EMS-coordination, Provider Governance and coordination,, Gothenburg, Sweden; Johan Olof Israelsson, Div of Cardiology, Kalmar, Sweden; Marie-Louise Södersved–Källestedt, Ctr for Clinical Res, Västerås, Sweden; Per Nordberg, Ctr for Resuscitation Science, Stockholm, Sweden; Peter Lundgren, Inst of Med, Gothenburg, Sweden; Johan Engdahl, Inst of Clinical Sciences, Stockholm, Sweden

4:30 PM

Board # 3098

Discrimination of Adverse Cardiac Events by the Myocardial Infarction and Cardiac Arrest Risk Calculator is Similar in Patients With or Without Prior Myocardial Infarction or Percutaneous Coronary Intervention Undergoing Bariatric Surgery

Brandon Peterson, **Kevin Mills** , Mehrdad Ghahramani, Andrew Foy, Penn State Hershey Medical Ctr, Hershey, PA

4:30 PM

Board # 3099

Higher Survival Chances After Out-of-hospital Cardiac Arrest in Patients Previously Seen by a Cardiologist

**Laura H. Van Dongen** , Sandra C.m. De Haas, Marieke Tabo Blom, Hanno L Tan, Amsterdam UMC, Location AMC, Amsterdam, Netherlands

4:30 PM

Board # 3100

Pregnancy and the Risk of Sudden Cardiac Arrest: A Population-Based Analysis

**Audrey Uy-Evanado** , Harpriya Chugh, Cedars-Sinai Medical Ctr, Los Angeles, CA; Eric Stecker, Oregon Health and Science Univ, Portland, OR; Jonathan Jui, Oregon Health and Science Univ, Wilsonville, OR; Kyndaron Reinier, Sumeet S Chugh, Cedars-Sinai Medical Ctr, Los Angeles, CA

4:30 PM

Board # 3101

ST Elevation Myocardial Infarction in Hospitalized Patients With Atrial Fibrillation

**Fangcheng Wu** , Memorial Hosp West, Pembroke Pines, FL; Pengyang Li, Saint Vincent Hosp, Worcester, MA; Richard A f Dixon, Su Pan, Qi Liu, Texas Heart Inst, Houston, TX

4:30 PM

Board # 3102

Failure of Non-Invasive Ventilation in Acute Heart Failure is Associated With Increased Mortality

**Thomas Stephen Metkus** , Johns Hopkins Univ Sch of Med, Luthvle Timon, MD; Steven Paul Schulman, Johns Hopkins Medical Insts, Baltimore, MD; Robert S Stephens, Johns Hopkins Univ, Baltimore, MD; Shaker Eid, Johns Hopkins Univ Sch of Med, Baltimore

4:30 PM

Poster Professor

Purav Mody, Dallas, TX

# Abstract Poster Session

## EP.APS.04 - Epidemiology of Chemotherapy Associated Cardiovascular Conditions

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 3063

Understanding the Impact of Hypertension Among Breast Cancer Patients Treated With Contemporary Cancer Therapies: 9-Year Trends From Two National Registries

**Rebecca R Carter** , The Ohio State Univ, Columbus, OH; Avirup Guha, Case Western Reserve Univ, Cleveland, OH; Reynaldo Sanchez, Ohio State Univ, Columbus, OH; Raquel Reinbolt, Ohio State Univ Sch of Med, Columbus, OH; Maryam Lustberg, Daniel Addison, Ohio State Univ, Columbus, OH

4:30 PM

Board # 3064

Anticoagulation Therapy for Atrial Fibrillation in Cancer Patients May Reduce the Incidence of Venous Thromboembolism

**Pengyang Li** , Mu Li, Saint Vincent Hosp, Worcester, MA; Fangcheng Wu, Memorial Hosp West, Pembroke Pines, FL; Ying Ning, Saint Vincent Hosp, Worcester, MA; Su Pan, Richard A f Dixon, Qi Liu, Texas Heart Inst, Houston, TX

4:30 PM

Board # 3065

Statin Use is Associated With Increased Overall Survival in Patients With Colorectal Cancer: Findings From a Cohort of 29,498 United States Veterans

**Chiara Melloni** , Duke Clinical Res Institu, Durham, NC; Gretchen Genevieve Kimmick, Duke Univ Medical Ctr, Durham, NC; Taofik Oyekunle, Leah L Zullig, Duke Univ Sch of Med, Durham, NC; Michel G Khouri, Duke Univ Medical Ctr, Durham, NC; Lauren Howard, Michael J Kelley, Duke Univ Sch of Med, Durham, NC; Susan Faye Dent, Duke Univ Cancer Ctr, Durham, NC

4:30 PM

Board # 3066

Subclinical Cardiotoxicity Post Anthracycline in an African Population

**Joseph O Abuodha** , Asim Jamal Shaikh, Jasmit Shah, Jeilan Mohamed, Anders Barasa, Agakhan Univ Hosp, Nairobi, Kenya

4:30 PM

Board # 3067

Effect of Aspirin on Venous Thromboembolism in Older Patients With Cancer

**Pengyang Li** , Ying Ning, Saint Vincent Hosp, Worcester, MA; Fangcheng Wu, Memorial Hosp West, Pembroke Pines, FL; Mu Li, Saint Vincent Hosp, Worcester, MA; Lingling Wu, Mount Sinai St Luke's and West, New York, NY; Kristina Duan, Baylor Coll of Med, Houston, TX; Qi Liu, Texas Heart Inst, Houston, TX

4:30 PM

Board # 3068

Burden and Impact of Takotsubo Cardiomyopathy in Patients Who Previously Underwent Mediastinal/Intrathoracic Radiation Therapy

Rupak Desai, Atlanta VA Medical Ctr, Decatur, GA; Upenkumar Patel, Nassau Univ Medical Ctr, East Meadow, NY; **Rushik Bhuva** , Geisinger Wyoming Valley Medical Ctr, Wilkes-Barre, PA; Mir Zeeshan Ali Khan, St. Peters Univ Hosp, New Brunswick, NJ; Muhammad Uzair Lodhi, Eastern Idaho Regional Med Ctr, Idaho Falls, ID; Nazia Farheen, Lake America Family Physicians, Clermont, FL; Abhimanyu Ravalani, St. Peters Univ Hosp, New Brunswick, NJ; Kishorbhai Gangani, Texas Health Arlington Memorial Hosp, Arlington, TX; Rajesh Sachdeva, Morehouse Sch of Med, Atlanta VA Medical Ctr & Emory Sch of Med, Atlanta, GA; Gautam Kumar, Emory Univ & Atlanta VA Medical Ctr, Decatur, GA

4:30 PM

Board # 3069

Association of Ibrutinib and Development or Worsening of Hypertension

**Dae Hyun Lee** , Fahad Hawk, Matthew Gliksman, Univ of South Florida, Tampa, FL; Josephine Emole, Henry Ford Health System, Detroit, MI; Isaac Rhea, Federico Viganego, Univ of South Florida and H. Lee Moffitt Cancer Ctr and Res Inst, Tampa, FL; Allan Welter-Frost, Merna Armanious, Univ of South Florida, Tampa, FL; Christine Walko, Bijal Shah, Julio C Chavez, Howard McLeod, Javier Pinilla-Ibarz, Matthew B Schabath, H. Lee Moffitt Cancer Ctr and Res Inst, Tampa, FL; Michael George Fradley, Univ of South Florida, Tampa, FL

4:30 PM

Board # 3070

Fluoropyrimidine-associated Cardiotoxicity: Patient Characteristics and Clinical Outcomes

**Inbar Raber** , Sarah Warack, Jaya Kanduri, Abby Pribish, Anuradha Godishala, Arielle Abovich, Sujithraj Dommaraju, Anna Orbite, Morgan B Frazer, Aarti Asnani, Beth Israel Deaconess Medical Ctr, Boston, MA

4:30 PM

Board # 3071

Orthostatic Hypotension and Tachycardia Syndrome in Patients Undergoing Hematopoietic Cell Transplantation

Edoardo Bressi, Alessandra Vecchie', Justin M Canada, Jose Chuquin, Dinesh Kadariya, Usman Piracha, Delia Endicott, Roshanak Markley, Amir Toor, **Antonio Abbate** , Virginia Commonwealth Univ, Richmond, VA

4:30 PM

Poster Professor

Susan Faye Dent, Durham, NC

4:30 PM

Board # 3072

Cardiac Toxicity and Cardiovascular Events Among Adult Patients Treated With Chimeric Antigen Receptor T-Cells: A Multi-Center Registry

**Raza M Alvi** , Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Michael G Fradley, Univ of South Florida Morsani Coll of Med and Moffitt Cancer Ctr, Tampa, FL; Matthew J Frigault, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Michael D Jain, Moffitt Cancer Ctr, Tampa, FL; Syed S Mahmood, New York-Presbyterian Hosp, Weil Cornell Medical Ctr, New York, NY; Magid Awadalla, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Dae Hyun Lee, Univ of South Florida Morsani Coll of Med and Moffitt Cancer Ctr, Tampa, FL; Daniel A Zlotoff, Lili Zhang, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Emmanuel Bassily, Univ of South Florida Morsani Coll of Med and Moffitt Cancer Ctr, Tampa, FL; Malek Z.O. Hassan, Zsofia D Drobni, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Isaac Rhea, Roohi Ismail-Khan, Univ of South Florida Morsani Coll of Med and Moffitt Cancer Ctr, Tampa, FL; Connor P Mulligan, Adam Rokicki, Dahlia Banerji, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Aleksandr Lazaryan, Moffitt Cancer Ctr, Tempa, FL; Bijal D Shah, Moffitt Cancer Ctr, Tampa, FL; Noopur Raje, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Julio C Chavez, Moffitt Cancer Ctr, Tampa, FL; Jeremy Abramson, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Frederick L Locke, Moffitt Cancer Ctr, Tampa, FL; Tomas G Neilan, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA

# Abstract Poster Session

## CH.APS.09 - Evaluating Healthcare Utilization and Long-Term Outcomes in Adult Congenital Heart Disease

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 4121

Risk Factors for Complications Following Cardiac Surgery at Children's Hospitals in Adults With Congenital Heart Disease

**Katherine B Salciccioli** , Danielle Guffey, Texas Children's Hosp, Houston, TX; Nancy Ghanayem, Childrens Hosp of Wisconsin, Houston, TX; Javier J Lasa, Texas Childrens Hosp, Houston, FL; Michael G Gaies, Univ of Michigan, Ann Arbor, MI; Stephanie MPN Fuller, Childrens Hosp of Philadelphia, Philadelphia, PA; Francis Kim, Medical Coll of Wisconsin, Milwaukee, WI; Andrew Smith, VUMC, Nashville, TN; Timothy Cotts, Univ of Michigan, Ann Arbor, MI; Jamie Causey, Texas Children's Hosp/Baylor Coll of Med, Houston, TX; Peter R Ermis, Baylor Coll Med, Houston, TX; Parag Jain, Texas Children's Hosp, Houston, TX

4:30 PM

Board # 4122

Pregnancy Outcomes in Women With Significant Valvular Heart Disease in Medium or Higher Human Development Index Countries: A Systematic Review and Meta-analysis

Robin Ducas, Univ of Manitoba, Winnipeg, MB, Canada; Angelo D Javier, Health Sciences North, Sudbury, ON, Canada; Rohan D'Souza, Mount Sinai Hosp, Toronto, ON, Canada; Candice Silversides, Univ of Toronto, Toronto, ON, Canada; **Wendy Tsang** , Toronto General Hosp, Univ Health Network, Toronto, ON, Canada

4:30 PM

Board # 4123

Variability in Healthcare Utilization by Adults With Congenital Heart Disease in Oregon

**Lidija Breznikar McGrath** , Katrina Ramsey, Oregon Health and Science Universit, Portland, OR; Paola C Roldan, Oregon Health Science Univ, Albuquerque, NM; Craig Stanford Broberg, Knight Cardiovascular Inst, Portland, OR; Abigail Khan, Oregon Health and Science Univ, Portland, OR

4:30 PM

Board # 4124

Predictors of 1-Year Mortality After Incident and Repeated Heart Failure Hospitalizations in Older Adults With Congenital Heart Disease

**Fei Wang** , Aihua Liu, Jay Brophy, Sarah Cohen, Michal Abrahamowicz, McGill Univ Health Ctr, Montreal, QC, Canada; Gilles Paradis, McGill Univ, Montreal, QC, Canada; Ariane J Marelli, McGill Univ Health Ctr, Montreal, QC, Canada

4:30 PM

Board # 4125

Rationale and Design of Ch Strong: Congenital Heart Survey to Recognize Outcomes, Needs, and Well-beinG

**Sherry L Farr** , Ctrs for Disease Control and Prevention, Atlanta, GA; Scott E Klewer, Univ of Arizona, Tucson, AZ; Wendy N Nembhard, Univ of Arkansas for Medical Sciences, Little Rock, AR; Caroline Alter, March of Dimes, Mamaroneck, NY; Karrie F Downing, Ctrs for Disease Control and Prevention, Atlanta, GA; Jennifer G Andrews, Univ of Arizona, Tucson, AZ; R Thomas Collins II, Stanford Univ Sch of Med and Lucile Packard Children's Hosp Stanford, Palo Alto, CA; Jill Glidewell, Ctrs for Disease Control & Preve, Atlanta, GA; Argelia Benavides, Univ of Arizona, Tucson, AZ; Anthony Goudie, Univ of Arkansas for Medical Sciences, Little Rock, AR; Tiffany Riehle-Colarusso, Ctrs for Disease Control and Prevention, Atlanta, GA; Lindsey Overman, Univ of Arkansas for Medical, Little Rock, AR; Aspen Riser, Matthew E Oster, Ctrs for Disease Control and Prevention, Atlanta, GA

4:30 PM

Board # 4126

Machine Learning Developed Algorithms to Identify Patients With Congenital Heart Disease From Large Claims Databases

**Ariane Marelli** , Chao Li, Aihua Liu, Liming Guo, James M Brophy, McGill Univ Health Ctr, Montreal, QC, Canada; Yi Yang, McGill Univ, Montreal, QC, Canada

4:30 PM

Board # 4127

Health-related Quality of Life in Patients With Adult Congenital Heart Disease - A Nation-wide Cross-sectional Questionnaire Survey -

**Ryo Konno** , Shunsuke Tatebe, Yasuhiko Sakata, Koichiro Sugimura, Kimio Satoh, Takashi Shiroto, Satoshi Miyata, Osamu Adachi, Masato Kimura, Tohoku Univ Graduate Sch of Med, Sendai, Japan; Yoshiko Mizuno, Junko Enomoto, Shigeru Tateno, Chiba Cardiovascular Ctr, Ichihara, Japan; Hiromichi Nakajima, Chiba Children's Hosp, Chiba, Japan; Kotaro Oyama, Iwate Medical Univ, Morioka, Japan; Yoshikatsu Saiki, Hiroaki Shimokawa, Tohoku Univ Graduate Sch of Med, Sendai, Japan

4:30 PM

Board # 4128

Comparison of Emergent Chest Pain Evaluation Among Adults With Congenital Heart Disease and Matched Controls

**Jordan M Gales** , Duke Univ Hosp, Durham, NC; Richard Krasuski, Jordan Awerbach, Duke Univ Medical Ctr, Durham, NC

4:30 PM

Board # 4129

Randomized Controlled Trial of a Transition Intervention Program for Young Adolescents With Congenital Heart Disease

**Andrew S Mackie** , Kathryn Rankin, Maryna Yaskina, Univ of Alberta, Edmonton, AB, Canada; Jody Gingrich, Michelle Schuh, Elina Williams, Stollery Children's Hosp, Edmonton, AB, Canada; David Nicholas, Univ of Calgary, Edmonton, AB, Canada; Gwen Rempel, Athabasca Univ, Athabasca, AB, Canada

4:30 PM

Board # 4130

The Evolving Surgical Burden of Fontan Failure: An Analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database

**John Serfas** , Duke Univ, Durham, NC; Nicholas D Andersen, Duke Univ Medical Ctr, Durham, NC; Karen Chiswell, Duke Clinical Res Inst, Durham, NC; Jeffrey P Jacobs, Johns Hopkins All Children's Hospit, Saint Petersburg, FL; Marshall L. Jacobs, Johns Hopkins Sch of Med, Baltimore, MD; Richard Krasuski, Duke Univ Medical Ctr, Durham, NC; Andrew Lodge, Duke Univ Med Ctr, Durham, NC; Dylan Thibault, Duke Clinical Res Inst, Durham, NC; Joseph W Turek, Duke Univ Medical Ctr, Durham, NC; Kevin D Hill, Duke Clinical Res Inst, Durham, NC

# Abstract Poster Session

## AT.APS.08 - Experimental and Therapeutic Approaches for Cardiovascular Disease

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 1094

Efficacy and Safety of Rilonacept in Recurrent Pericarditis: A Multicenter Phase 2 Clinical Trial

**Allan Klein** , Cleveland Clinic, Cleveland, OH; David Lin, Minneapolis Heart Inst, Minneapolis, MN; Paul Cremer, Cleveland Clinic, Cleveland, OH; Saifullah Nasir, Stat! Cardiology, Chicago, IL; S Allen Luis, Mayo Clinic, Rochester, MN; Antonio Abbate, Virginia Commonwealth Univ, Richmond, VA; Asif Akhtar, Res Consultants, Houston, TX; Andrew Ertel, Heart and Vascular Inst of MedStar Washington Hosp Ctr., Washington, DC; Martin M Lewinter, Univ of VT Med Ctr, Burlington, VT; Anna Beutler, John F Paolini, Fang Fang, Kiniksa Pharmaceuticals Corp., Lexington, MA; Steven Chang, NJS, Bridgewater, NJ; Larisa Collins, Randy Perrin, Kasia Warchol, Sharon Crugnale, Kiniksa Pharmaceuticals Corp., Lexington, MA

4:30 PM

Board # 1095

Pharmacological Blockade of C-C Chemokine Receptor 4 Exacerbates Atherosclerosis in Apolipoprotein E-Deficient Mice

**Hilman Zulkifli Amin** , Univs Indonesia, Jakarta, Indonesia; Naoto Sasaki, Sayo Horibe, Shoji Kawauchi, Kobe Pharmaceutical Univ, Kobe, Japan; Kazuhiko Matsuo, Takashi Nakayama, Kindai Univ, Osaka, Japan; Yoshiyuki Rikitake, Kobe Pharmaceutical Univ, Kobe, Japan; Ken-Ichi Hirata, Kobe Univ, Kobe, Japan

4:30 PM

Poster Professor

Masuko Ushio-fukai, Augusta, GA

4:30 PM

Board # 1096

Combined Biomechanical and Pharmacological Treatments Prime Pluripotency in Mouse Embryonic Fibroblasts

**Andrew Sligar** , The Univesity of Texas at Austin, Austin, TX; Jason Lee, Univ of Texas at Austin, Austin, TX; Miguel Ochoa, Pablo Maceda, Eun Yoon, Lara Samarneh, Mitchell Wong, The Univesity of Texas at Austin, Austin, TX; Aaron Baker, The Univ of Texas at Austin, Austin, TX

4:30 PM

Board # 1097

Central Hypertension in Apparently Normotensive Patients With Thoracic Aortic Aneurysms: Prevalence and Association With Aneurysm Expansion

**Jasjit Rooprai** , Univ of Ottawa, Ottawa, ON, Canada; Munir Boodhwani, Univ Ottowa Heart Inst, Ottawa, ON, Canada; Luc M Beauchesne Jr., Ottawa Heart Inst, Ottawa, ON, Canada; Kwan L Chan, Univ of Ottawa Heart Inst, Ottawa, ON, Canada; Carole Dennie, Univ of Ottawa Heart Intsitut, Ottawa, ON, Canada; Sudhir Nagpal, Univ of Ottawa, Ottawa, ON, Canada; Thais Coutinho, Univ of Ottawa Heart Inst, Ottawa, ON, Canada

4:30 PM

Board # 1098

**Effect of Sarpogrelate, a 5-HT** 2A **Antagonist, on Platelet Aggregation in Patients With Stable Atherosclerotic Cardiovascular Disease: Potential for Practical Use at Preoperative Period**

**Yeong-Min Lee** , Young-Ah Park, Han-Young Jin, Jeong-Sook Seo, Jae-sik Jang, Dae-Kyeong Kim, Dong-Soo Kim, Tae-Hyun Yang, Busan-Baik hospital, Busan, Korea, Republic of

4:30 PM

Board # 1099

MicroRNA-26a Targeted Therapy for Abdominal Aortic Aneurysms

Lina A Elfaki, Univ of Toronto, Toronto, ON, Canada; Razak A Pirani, Zaman Afrasiabi, Mariah Colussi, Pratiek N Matkar, Hao H Chen, Michael Kuliszewski, **Howard Leong-poi** , St. Michael's Hosp, Toronto, ON, Canada

4:30 PM

Board # 1100

Impact of Cardiovascular Events on Short and Long-Term Mortality Following Liver Transplantation

**Vikram Sharma** , Jacek B Cywinski, KV Narayanan Menon, Jamak Esfeh Modaresi Esfeh, Ravi Nair, Parth Parikh, Teresa Diago, Bijan Eghtesad, Cristiano Quintini, Maan Fares, Cleveland Clinic, Cleveland, OH

4:30 PM

Board # 1101

Clinical Benefits of Antithrombotic Therapy in Patients With Atrial Fibrillation Comorbid With Heart Failure and Coronary Artery Disease - A Report From the Chart-2 Study -

**Takashi Shiroto** , Yasuhiko Sakata, Kotaro Nochioka, Ruri Abe, Shintaro Kasahara, Masayuki Sato, Hajime Aoyanagi, Takahide Fujihashi, Shinsuke Yamanaka, Hideka Hayashi, Masanobu Miura, Jun Takahashi, Satoshi Miyata, Hiroaki Shimokawa, Tohoku Univ Graduate Sch of Med, Sendai, Japan

4:30 PM

Board # 1102

Cardiovascular Diseases and Inpatient Mortality in Idiopathic Pulmonary Fibrosis

Jeanne Ho, **Willy Roque** , Aldo Barajas, Omry Zuckerman, Eman Rashed, Rutgers Univ - New Jersey Medical Sch, Newark, NJ

4:30 PM

Board # 1103

Relation of Red Blood Cell Distribution Width to Risk of Major Adverse Cardiovascular Events, Death, and Effect of Alirocumab After Acute Coronary Syndrome

**Patrick Maurice Moriarty** , Univ of Kansas Medical Ctr, Kansas City, KS; Philippe Gabriel Steg, Hop Bichat, Paris, France; Lauryn K Gorby, Univ of Kansas Medical Ctr, Kansas City, KS; Andreas M Zeiher, Goethe Univ, Frankfurt Am Main, Germany; Harvey D White, Auckland City Hosp, Auckland, New Zealand; Timothee Sourdille, Sanofi, Bridgewater, NJ; Matthew T Roe, Duke Clinical Res Inst, Durham, NC; Michael J Louie, Regeneron Pharmaceuticals, Tarrytown, NY; J Wouter Jukema, Leiden Univ Medical Ctr, Leiden, Netherlands; Robert A Harrington, Stanford Univ, Stanford, CA; Shaun Geoffrey Goodman, St. Michael's Hosp, Toronto, ON, Canada; Rafael Diaz, Insto Cardiovascular de Rosario, Rosario, Argentina; Vera A Bittner, Univ of Alabama at Birmingham, Birmingham, AL; Deepak L Bhatt, Brigham and Women's Hosp Heart & Vascular Ctr, Boston, MA; Michael Szarek, State Univ of New York, Brooklyn, NY; Helen Li, Regeneron Pharmaceuticals, Tarrytown, NY; Gregory G Schwartz, Univ of Colorado Sch of Med, Aurora, CO; for the ODYSSEY OUTCOMES Investigators

4:30 PM

Board # 1104

Saddle Pulmonary Embolism Treatment Patterns in the United States

**Joshua Benjamin Goldberg** , Ansab Haider, Westchester Medical Ctr, Valhalla, NY; Aaqib Habib Malik, Westchester Medical Ctr, Harriman, NY; Syed Zaid, Westchester Medical Ctr, Valhalla, NY

4:30 PM

Board # 1105

Chronic Thromboembolic Pulmonary Hypertension Caused by Combination of Repeated Clot Embolization With Inhibition of Angiogenesis in Rabbits

**Rozenn Quarck** , Allard Wagenaar, Birger Tielemans, Univ of Leuven - KU Leuven, Leuven, Belgium; Frederic Perros, UMR-S 999, INSERM and Univ Paris–Sud, Le Plessis Robinson, France; Peter Dorfmuller, Univ Hosp of Giessen and Marburg, Giessen, Germany; Catharina Belge, Marion Delcroix, Univ of Leuven - KU Leuven, Leuven, Belgium

# Abstract Poster Session

## CH.APS.07 - Fontan Survivorship: Predicting Outcomes in Adults with the Fontan Circulation

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 4101

Prevalence of Nocturnal Hypoxia in a Cohort of Adult Fontan Patients Living at Altitude

**Christina Stevens** , Ronnie Jacobsen, Amber Khanna, Elizabeth Yeung, Dominik Wiktor, Madhukar Kollengode, Gareth Morgan, Joseph Kay, Univ of Colorado Sch of Med, Aurora, CO

4:30 PM

Board # 4102

Decreased Blood Platelet Count and Serum Level of Cholesterol Reflects the Functional Deterioration of Advanced Fontan Associated Liver Disease

**Chun Wei Lu** , Natl Taiwan Univ Children's Hosp, Taipei, Taiwan; Chih Horng Wu, Miao Tzu Huang, Natl Taiwan Univ Hosp, Taipei, Taiwan; Chee Seng Lee, Taipei Tzu Chi Hosp, New Taipei City, Taiwan; Ming Tai Lin, Shuenn-Nan Chiu, Chun An Chen, Jou Kou Wang, Mei Hwan Wu, Natl Taiwan Univ Children's Hosp, Taipei, Taiwan

4:30 PM

Board # 4103

Lymphopenia is a Marker for Hepatic Disease Severity and Heart Failure Independent of Hemodynamics in Fontan Subjects

**Anna L Scandinaro** , Cleveland Clinic, Cleveland, OH; Michael McCann, Penn State Health, Hershey, PA; Anisa Chaudhry, Penn State Health Milton S. Hershey Medical Ctr, Hershey, PA; William R Davidson, Penn State Univ Coll Med, Hershey, PA

4:30 PM

Board # 4104

Abdominal Skeletal Muscle Index as a Potential Novel Biomarker in Adult Fontan Patients

**Mathias Possner** , Cincinnati Children's Hosp, Cincinnati, OH; Tarek Alsaied, Cincinnati Children's Hosp, Cincinnati, OH; Andrew Trout, David Morales, Gruschen Veldtman, Cincinnati Children's Hosp, Cincinnati, OH

4:30 PM

Board # 4105

Impact of Atrial Fibrillation on Hemodynamics of Fontan Circulation: Fontan Computational Model Study

**Koichi Sughimoto** , Mazankowski Alberta Heart Inst, Edmonton, AB, Canada; Tetsuya Ueda, Takashi Fujiwara, Hao Liu, Chiba Univ, Chiba, Japan

4:30 PM

Board # 4106

Diuretic Use is Associated With Worse Transplant-Free Survival in Adult Fontan Patients

**Juan M Ortega-Legaspi** , Hosp of the Univ of Pennsylvania, Philadelphia, PA; Katherine Awh, Children's Hosp of Philadelphia, Philadelphia, PA; Bhavesh Patel, Hosp of the Univ of Pennsylvania, Philadelphia, PA; Abhinay Ramachandran, Univ of Pennsylvania, Philadelphia, PA; Joyce Wald, Srinivas Denduluri, Alexandra Archer, Hosp of the Univ of Pennsylvania, Philadelphia, PA; David Drajpuch, Stephanie Fuller, Christopher Mascio, Children's Hosp of Philadelphia, Philadelphia, PA; Emily Ruckdeschel, Lynda Tobin, Yuli Y Kim, Hosp of the Univ of Pennsylvania, Philadelphia, PA

4:30 PM

Board # 4107

Increased Visceral Fat is Associated With Higher Pulmonary Vascular Resistance in Adults With Fontan Circulation

**Adam M Lubert** , Tarek Alsaied, Cincinnati Children's Hosp, The Heart Inst, Cincinnati, OH; Andrew T Trout, Jonathan R Dillman, Cincinnati Children's Hosp, Cincinnati, OH; Bryan H Goldstein, Cincinnati Children's Hosp, The Heart Inst, Cincinnati, OH

4:30 PM

Board # 4108

Impact of Respiratory Exchange Ratio on Prognostic Power of Peak Oxygen Consumption in Adults With Fontan Circulation

**Jianli Niu** , Aliana Godoy, Memorial Healthcare System, Hollywood, FL; Bibhuti B Das, Joe DiMaggio Children's Hosp, Memorial Health Care, Hollywood, FL

4:30 PM

Board # 4110

Fontan-Associated Nephropathy: Predictors and Outcomes

**Jacqueline Nguyen Khuong** , Murdoch Children's Res Inst, Melbourne, Australia; Thomas G Wilson, Royal Children's Hosp, Melbourne, Australia, Parkville, Australia; Ajay J Iyengar, Royal Children's Hosp, Parkville, Australia; Leeanne Grigg, Royal Melbourne Hosp, Melbourne, Australia; Andrew Michael Bullock, PMH Children's Cardiac Ctr, Perth, Australia; David Celermajer, Royal Prince Alfred Hosp, Sydney, Australia; Patrick Disney, Royal Adelaide Hosp, Adelaide, Australia; Tim Hornung, Starship Child Health, Auckland, New Zealand; Vishva Wijesekera, The Prince Charles Hosp, Queensland, Australia; Diana Zannino, Murdoch Children's Res Institu, Parkville; Yves d'Udekem, Royal Childrens Hosp, Melbourne, Belgium

4:30 PM

Poster Professor

Yuli Y Kim, Philadelphia, PA

# Abstract Poster Session

## HF.APS.09 - From Stage A to Stage D Heart Failure

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2136

Serum Uric Acid Level and Subclinical Left Ventricular Dysfunction: A Community-based Cohort Study

**Koki Nakanishi** , Masao Daimon, Yuriko Yoshida, Jumpei Ishiwata, Naoko Sawada, Megumi Hirokawa, The Univ of Tokyo, Tokyo, Japan; Hidehiro Kaneko, Brandenburg Heart Ctr, Bernau bei Berlin; Tomoko Nakao, The Univ of Tokyo, Tokyo, Japan; Yoshiko Mizuno, Harvard Medical Sch, Beverly, MA; Hiroyuki Morita, The Univ of Tokyo, Tokyo, Japan; Marco Di Tullio, Columbia Presbyterian Med Ctr, New York, NY; Shunichi Homma, Columbia Univ, New York, NY; Issei Komuro, The Univ of Tokyo, Tokyo, Japan

4:30 PM

Board # 2137

Development of a Risk Score for Incident Latent Heart Failure in a Japanese General Population: The Suita Study

**Yoshihiro Kokubo** , Natl Cerebral and Cardiovascular Ctr, Suita, Osaka, Japan; Aya Higashiyama, NCVC, Suita, Japan; Makoto Watanabe, Natl Cerebral and Cardiovascular Ctr, Suita, Osaka, Japan

4:30 PM

Board # 2138

Spanish-speaking Heart Failure Patients Perceive Increased Confidence and Health Communication Skills Following a Spanish-language Self-care Intervention

**Jill Howie Esquivel** , Univ of Virginia, Charlottesville, VA; Linda K Ottoboni, Stanford Hosp & Clinics, San Mateo, CA; Lucy Selman, Univ of Bristol, Bristol, United Kingdom

4:30 PM

Board # 2139

Catheter Ablation of Atrial Fibrillation in Patients With Arrythmia Induced Cardiomyopathy

**Giichi Nitta** , Osamu Inaba, Yohei Tamura, Gaku Narita, Hirotaka Yano, Shunichi Kato, Toshikazu Kono, Takashi Ikenouchi, Kazuya Murata, Yasuaki Hada, Miki Kanoh, Tomomasa Takamiya, Yukihiro Inamura, Ken Negi, Akira Sato, Tsunehiro Yamato, Yutaka Matsumura, Japanese Red Cross Saitama Hosp, Saitama-city, Japan; Junichi Nitta, Sakakibara Heart Inst, Tokyo, Japan

4:30 PM

Board # 2140

De Novo Subcutaneous Implantable Cardioverter-Defibrillator Placed in Patient With Left Ventricular Assist Device

**Emrie Tomaiko** , Banner Univ Medical Ctr, Phoenix, AZ; Aneesh Kalya, Arizona State Univ, Tempe, AZ; Marie Olsen, Heather Bahm, Sharon Kusne, Carla Lockhart, Banner Univ Medical Ctr, Phoenix, AZ; Wilber Su, Banner Univ Medical Ctr, Paradise Vly, AZ

4:30 PM

Board # 2141

Modifiable Risk Factor Control and Risk for Heart Failure With Preserved Ejection Fraction (HFpEF) versus Reduced Ejection Fraction (HFrEF): The Atherosclerosis Risk in Communities Study (ARIC)

**Carine E. Hamo** , Lucia Kwak, Roberta Florido, Justin Echouffo-Tcheugui, Roger Blumenthal, Johns Hopkins Univ, Baltimore, MD; Laura R Loehr, Univ North Carolina Chapel Hill, Chapel Hill, NC; Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD; Vijay Nambi, Michael E DeBakey Veterans Affairs Hosp, Sugar Land, TX; Christie M Ballantyne, Baylor Coll Med, Houston, TX; Elizabeth Selvin, Johns Hopkins Univ, Baltimore, MD; Aaron Folsom, Univ of Minnesota, Minneapolis, MN; Gerardo M Heiss, Univ North Carolina, Chapel Hill, NC; Josef Coresh, Johns Hopkins SPH Welch Ctr, Baltimore, MD; Chiadi Ericson Ndumele, Johns Hopkins Hosp, Baltimore, MD

4:30 PM

Board # 2142

Cardiac Mri Demonstrates Findings of Subclinical Hfpef in Patients With Ckd Stage 3-4

**Ann A Wang** , Xuan Cai, Northwestern Univ Feinberg Sch of Med, Chicago, IL; Pottumarthi Prasad, Evanston Northwestern Healthcare, Evanston, IL; Stuart M Sprague, Evanston Hosp, Evanston, IL; James C Carr, Northwestern Univ Feinberg Sch of Med, Chicago, IL; Myles Wolf, Duke Univ, Durham, NC; Joachim H IX, Univ of California San Diego, San Diego, CA; Geoffrey Block, Reata Pharmaceuticals, Golden, CO; Michel Chonchol, Univ of Colorado Hosp, Aurora, CO; Kalani Raphael, Univ of Utah, Salt Lake City, UT; Alfred K Cheung, Univ of Utah Health, Salt Lake City; Dominic Raj, George Washington Univ, Washington, DC; Jennifer Gassman, Cleveland Clinic, Cleveland, OH; John Middleton, Duke Univ Sch of Med, Durham; Linda F Fried, VA Pittsburgh Healthcare System, Pittsburgh, PA; Roberto Sarnari, Tamara Isakova, Rupal Mehta, Northwestern Univ, Chicago, IL; the COMBINE study group

4:30 PM

Board # 2143

Stage a Heart Failure Trends in the Social Media Era

**Ashley Ezema** , Quentin R Youmans, Allen S Anderson, Kamari C Jackson, Edwin Mandieka, Ramael Ohiomoba, Northwestern Univ, Chicago, IL; Oluseyi Princewill, Johns Hopkins Hosp, Baltimore, MD; Clyde W Yancy Jr., Ike S Okwuosa, Northwestern Univ, Chicago, IL

4:30 PM

Board # 2144

High Prevalence of Left Ventricular Diastolic Dysfunction in Very Elderly Patients

**Yoshiyuki Orihara** , Hyogo Coll of Med, Nishinomiya, Japan; Masanori Asakura, Hyogo Coll of Med, Hyogo, Japan; Yoshitaka Okuhara, Hyogo Coll of Med, Nishinomiya City, Japan; Yuki Matsumoto, Hyogo Coll of Med, Nishinomiya-shi, Japan; Masaharu Ishihara, Hyogo Coll of Med, Nishinomiya, Japan

# Abstract Poster Session

## GE.APS.02 - Genetic Epidemiology, Genomics and Pharmacogenomics II

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 1137

The Causal Relevance of Systemic Inflammation for Risk of Atrial Fibrillation

**Christian Fielder Camm** , Maysson Ibrahim, Elsa Valdes-Marquez, Barbara Casadei, Jemma C Hopewell, Univ of Oxford, Oxford, United Kingdom

4:30 PM

Board # 1138

Comprehensive Gene Evaluation in Early-Onset Atrial Fibrillation Using Whole Exome Sequencing

**Brandon Chalazan** , Univ of British Columbia, Vancouver, BC, Canada; Jason Roberts, Western Univ, London, ON, Canada; Rafik Tadros, Univ of Montreal, Montreal, QC, Canada; Emma Leach, Anna Lehman, Zachary Laksman, Univ of British Columbia, Vancouver, BC, Canada

4:30 PM

Board # 1139

Height as a Causal Risk Factor for Atrial Fibrillation: A Mendelian Randomization Study

**Michael Levin** , Renae Judy, Univ of Pennsylvania, Philadelphia, PA; Regeneron Genetics Center; Daniel Rader, Benjamin F Voight, Univ of Pennsylvania, Philadelphia, PA; Scott M DAMRAUER, Universtiy of Pennsylvania, Philadelphia, PA

4:30 PM

Board # 1140

Novel Mediated and Causal Links Between Risk Factors and Cardiometabolic Outcomes: A Complex Network Mendelian Randomization

**Xiaodong Zhuang** , First Affiliated Hosp, Sun Yat-Sen Univ, Guangzhou, China; Lizhen Liao, Guangdong Pharmaceutical Univ, Guangzhou Higher Education Mega Ctr, Guangzhou, China; Huaqiang Zhou, Sun Yat-Sen Univ Cancer Ctr, State Key Lab of Oncology in South China, Collaborative Innovation Ctr for Cancer Med, Guangzhou, China; Xinxue Liao, First Affiliated Hosp, Sun Yat-Sen Univ, Guangzhou, China

4:30 PM

Board # 1141

Pharmaco-omics of Clopidogrel Response in African Americans- An African-American Cardiovascular Pharmacogenetic CONsorTium Study

**Tanima De** , Cristina Alarcon, Layan Nahlawi, Juan Avitia, Bianca Lec, Mohammed Shaazuddin, Mohammed Nooruddin, Northwestern Univ, Chicago, IL; Diana Moreno, Univ of Illinois, Chicago, IL; Myurani Sathyanarayanan, Univ of Illinois at Chicago, Chicago, IL; Edith Nutescu, Univ of Illinois, Chicago, IL; April Barbour, George Washington Univ, Chicago, IL; Jeff Banagan, Georgetown Univ, Chicago, IL; Olivia Gordon, George Washington Univ, Washington DC, DC; Tharani Jeyaram, Mary Harris, Sarah Bradbury, Univ of Chicago, Chicago, IL; Ramesh Subrahmanyam, U.S. Dept of Veterans Affairs, Chicago, IL; Matthew Tuck, George Washington Univ, Washington DC; Arthur Harralson, Shenandoah Univ, Winchester, VA; Paula Friedman, Northwestern Univ, Chicago, IL; David Meltzer, Univ of Chicago, Chicago; Travis O'Brien, George Washington Univ, Washington DC, DC; Minoli A Perera, Northwestern Univ, Chicago, IL

4:30 PM

Board # 1142

Warfarin Pharmacogenomics Algorithm Better Predicts Daily Warfarin Dose in Midwest Population

**Christopher J Arendt** , Magali Disdier Moulder, Ross Dierkhising, Viral Desai, Richard Weinshilboum, Liewei Wang, Nicholas B Larson, Suzette J Bielinski, Naveen L Pereira, Mayo Clinic, Rochester, MN

4:30 PM

Board # 1143

Efficacy and Tolerability of Elamipretide in Patients With Barth Syndrome: Results From Tazpower, a Randomized, Double-Blind, Placebo-Controlled, Crossover and Open-Label Extension Trial

**Hilary J Vernon** , Johns Hopkins Univ, Baltimore, MD; WIlliam R Thompson III, John Hopkins, Baltimore, MD; Anthony Aiudi, John J Jones, Jim Carr, Stealth BioTherapeutics, Newton, MA; Brittany DeCroes Hornby, Kennedy Krieger Inst, Baltimore, MD

4:30 PM

Board # 1144

Metabolomic Profiling of Engineered Skeletal Myobundles Identifies a Plasma Biomarker for Statin Associated Musculoskeletal Symptoms (SAMS)

Yiling Liu, Anandita Ananthakumar, Will Thompson, Rachel Myers, Rima Kaddurah-Daouk, Laura Dubois, Duke Univ, Durham, NC; George A Truskey, Duke Univ Biomed Engineering, Durham, NC; **Deepak Voora** , Duke Univ, Durham, NC

4:30 PM

Board # 1145

**Novel** CYP2C19 **Genetic Variants Associated With Stent Thrombosis - A Next Generation Sequencing Study**

**Lingxin Zhang** , Joel A Morales-Rosado, Kashish Goel, Mayo Clinic, Rochester, MN; Axel Akerblom, Uppsala Clinical Ctr, Uppsala, Sweden; Saurabh Baheti, John Black, Mayo Clinic, Rochester, MN; Niclas Eriksson, Uppsala Univ, Uppsala, Sweden; Lars C Wallentin, Uppsala Clinical Res Ctr, Uppsala, Sweden; Stefan K James, UCR, Uppsala, Sweden; Robert F Storey, Univ Sheffield Medical Sch, Sheffield, United Kingdom; Shaun Geoffrey Goodman, St Michaels Hosp, Toronto, ON, Canada; Gregory Jenkins, Bruce Eckloff, Suzette J Bielinski, Hugues Sicotte, Stephen Johnson, Veronique L Roger, Liewei Wang, Richard Weinshilboum, Eric Klee, Charanjit Rihal, Naveen L Pereira, Mayo Clinic, Rochester, MN

4:30 PM

Board # 1146

Frequency of Potentially Clinically Relevant Variants of CYP2C19 And SLCO1B1 in a Large Direct-to-Consumer Genetic Database

**Philip E Empey** , Univ of Pittsburgh, Pittsburgh, PA; Cindy Kosinski, Alison Chubb, Jianan Zhan, Hoang Nhan, 23andMe, Mountain View, CA; Kelly E Caudle, St. Jude Children's Res Hosp, Memphis, TN; Esther Kim, 23andMe, Mountain View, CA

4:30 PM

Poster Professor

Amber L Beitelshees, Baltimore, MD

4:30 PM

Board # 1147

Genetic Elimination of Calpain 4 Decreases Cardiac Injury by Improving Mitochondrial Function

Jeremy Thompson, Ying Hu, VCU, Richmond, VA; Edward Joseph Lesnefsky, Virginia Commonwealth Univ, Richmond, VA; **Qun Chen** , VCU, Richmond, VA

4:30 PM

Board # 1148

Interaction Between Drinking Habit and ALDH2 Genotype as a Risk Factor for Atrial Fibrillation

**Takayoshi Yamashita** , Yuichiro Arima, Toshifumi Ishida, Suguru Nagamatsu, Ryota Sato, Kenshi Yamanaga, Kenji Sakamoto, Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

# Abstract Poster Session

## HF.APS.06 - Heart Failure and Cardiomyopathies I

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2102

NOX4 Contributes to Diastolic Dysfunction Through Impaired Mitochondrial Turnover

**Andrey Lozhkin** , Aleksandr E Vendrov, Roberto Ramos-Mondragon, Mark Stevenson, Univ of Michigan, Ann Arbor, MI; Nageswara R Madamanchi, Univ Michigan, Ann Arbor, MI; Marschall S Runge, Univ of Michigan, Ann Arbor, MI

4:30 PM

Board # 2103

The Potential Clinical Role of Cathepsin K and Autophagy in the Prevention of Alcoholic Cardiomyopathy

**Rui Guo** , Hui Yang, Hebei Univ, Baoding, China; Yunliang Zhang, Baoxin Li, Xin Liu, Baoding No.1 Central Hosp, Baoding, China; Li Zhong, Western Univ of Health Sciences, Pomona, CA

4:30 PM

Board # 2104

Improvement in LVEF in Outpatients With Heart Failure With Reduced Ejection Fraction: Data From CHAMP-HF

**Adam David DeVore** , Duke Clinical Res Inst, Durham, NC; Anne Hellkamp, Duke Clinical Res Inst, Bothell, WA; Laine E Thomas, Duke Univ, Durham, NC; Puza P. Sharma, Novartis Pharmaceutical Corp, East Hanover, NJ; Nancy M Albert, Cleveland Clinic, Chesterland, OH; Javed Butler, Emory, Atlanta, GA; J Herbert H Patterson, Univ of North Carolina, Chapel Hill, NC; John Spertus, Mid America Heart Inst, Kansas City, MO; Fredonia Williams, Mended Hearts, Huntsville, AL; Carol Duffy, Novartis Pharmaceutical Corp, East Hanover, NJ; Adrian F Hernandez, Duke Univ Sch of Med, Durham, NC; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA

4:30 PM

Board # 2105

Systemic Vascular Distensibility is an Important Determinant of Exercise Performance in Heart Failure With Preserved Ejection Fraction

**Mark Schoenike** , Robyn Farrell, John Sbarbaro, Thomas Cunningham, Kathryn Hardin, Matthew G Nayor, Massachusetts General Hosp, Boston, MA; Jennifer E Ho, Massachusetts General Hosp, Newton, MA; Gregory Lewis, Rajeev Malhotra, Massachusetts General Hosp, Boston, MA

4:30 PM

Board # 2106

Epicardial Adipose Tissue Effects on Diastolic Function: A Local or Systemic Process?

**Shiva Reddy** , Univ of Texas Southwestern Medical Ctr, Dallas, TX; Katrin Dias, Inst for Exercise and Environmental Med, Texas Health Presbyterian Dallas and Univ of Texas Southwestern Medical Ctr, Dallas, TX; Kirsten Peters, Radboud Univ Medical Ctr, Nijmegen, Netherlands; Christopher Hearon, Michinari Hieda, Satyam Sarma, Inst for Exercise and Environmental Med, Texas Health Presbyterian Dallas and Univ of Texas Southwestern Medical Ctr, Dallas, TX

4:30 PM

Board # 2107

Echocardiographic Derived Pulmonary Artery Wedge Pressure is Associated With Mortality, Functional Capacity, and Hospitalizations in Chronic Systolic Heart Failure

**Patrick Stafford** , Kenneth Bilchick, Univ of Virginia, Charlottesville, VA; Hunter Mwansa, Case Western Reserve Univ, Cleveland, OH; Khadijah Breathett, Univ of Arizona Health Sciences, Tuscon, AZ; Fardous Abeya, Jamey Cutts, Nishaki M Mehta, Univ of Virginia, Charlottesville, VA; Mwenya Mubanga, Uppsala Univ, Uppsala, Sweden; Sthuthi David, Comfort Elumogo, Persey Bediako, Idil Aktan, Steve Noutong, Olusola Laja, Nora Tolbert, Younghoon Kwon, Univ of Virginia, Charlottesville, VA; Lorrita Kabwe, Agnes Mtaja Mwala, Univ of Zambia, Lusaka, Zambia; Samson Okello, Mohammad Abuannadi, James Bergin, Sula Mazimba, Univ of Virginia, Charlottesville, VA

4:30 PM

Board # 2108

Assisted Reproductive Technologies Induced Left Ventricular Hypertrophy Progresses to Heart Failure in Mice

**Rodrigo Soria** , Théo Meister, Afzal Dogar, Stefano Rimoldi, Urs Scherrer, Emrush Rexhaj, Inselspital, Bern, Switzerland

4:30 PM

Board # 2109

Systemic Inflammation Predicts Thoracic Radiotherapy Induced Cardiomyopathy

**Justin M Canada** , Georgia Thomas, Cory R Trankle, Salvatore Carbone, Virginia Commonwealth Univ, Richmond, VA; Leo Francis Buckley III, Brigham and Women's Hosp, Boston, MA; Benjamin W Van Tassell, Virginia Commonwealth Univ, Midlothian, VA; Hayley Billingsley, VCU Health Systems, Richmond, VA; Ronald Evans, Ryan Garten, Virginia Commonwealth Univ, Richmond, VA; Elisabeth Weiss, VCU, Richmond, VA; Antonio Abbate, Virginia Commonwealth Univ, Richmond, VA

4:30 PM

Board # 2110

Effect of Stage B HFpEF on Diastolic Peak Filling Rates in Obese Individuals, and the Impact of 1 Year of Exercise Training

**Michinari Hieda** , UT Southwestern Medical Ctr, Dallas, TX; Christopher Hearon, Katrin Dias, UT Southwestern Medical Ctr, Dallas, Dallas, TX; Rakushumimarika Harada, Texas Health Presbyterian Hosp, Dallas, TX; Yogamaya Mantha, Texas Health Presbyterian Hosp, Allen, TX; James MacNamara, Dean Palmer, UT Southwestern Medical Ctr, Dallas, Dallas, TX; Mitchel Samels, Braden Everding, UT Southwestern Medical Ctr, Dallas, TX; Sheryl A Livingston, Margot Morris, IEEM, Dallas, TX; Benjamin D Levine, UT Southwestern Medical Ctr, Dallas, TX; Satyam Sarma, IEEM UTSW, Dallas, TX

4:30 PM

Board # 2111

Left Ventricular Concentric Remodeling As A Cause Of Impaired Cardiorespiratory Fitness In Patients With Heart Failure And Preserved Ejection Fraction

**Justin Heizer** , Justin M Canada, Salvatore Carbone, Virginia Commonwealth Univ, Richmond, VA; Benjamin W Van Tassell, Virginia Commonwealth Univ, Midlothian, VA; Ross Arena, Univ Illinois Chicago, Chicago, IL; Antonio Abbate, Virginia Commonwealth Univ, Glen Allen, VA

4:30 PM

Poster Professor

Sheldon Litwin, Charleston, SC

4:30 PM

Board # 2112

Systemic Pulse Pressure to Central Venous Pressure Ratio is Associated With Adverse Clinical Outcomes in Advanced Heart Failure

**Jamey Cutts** , Kenneth C Bilchick, Matt Miller, Univ of Virginia, Charlottesville, VA; Idil Aktan, Univ of Virginia, Charlottesvle, VA; Patrick Stafford, Fardous Abeya, Younghoon Kwon, Nishaki M Mehta, Steve Noutong, Sthuthi David, Univ of Virginia, Charlottesville, VA; Khadijah Breathett, Univ of Arizona, Tucson, AZ; Mwenya Mubanga, Uppsala Univ, Uppsala, Sweden; Hunter Mwansa, Case Western Reserve, Cleveland, OH; Sula Mazimba, Univ of Virginia, Charlottesville, VA

4:30 PM

Board # 2113

Elevated Serum St2 is Associated With Higher Hospitalization Rates in Caucasian and African-American Outpatients With Stage C Heart Failure

Panagiotis Savvoulidis, Royal Brompton & Harefield NHS Fndn Trust, London, United Kingdom; James Snider, Critical Diagnostics, San Diego, CA; Sahil Rawal, Stony Brook Univ, Stony Brook, NY; Alanna Morris, Emory Univ Sch Med, Atlanta, GA; Javed Butler, Univ of Mississippi, Jackson, MS; Vasiliki Georgiopoulou, Emory Univ, Atlanta, GA; **Andreas P Kalogeropoulos** , Stony Brook Univ, Stony Brook, NY

# Abstract Poster Session

## PH.APS.08 - Homeostatic Mechanisms in Pulmonary Vascular Disease

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2283

WWOX Contributes to the Cancer-Like Microenvironment in Pulmonary Hypertension

**Marta T Gomes** , Indiana Univ, Indianapolis, IN; Jiwang Chen, Shahzaib Ghazi Haider, Univ of Illinois at Chicago, Chicago, IL; Yang Bai, Indiana Univ, Whitestown, IN; Jacob Saliba, Patricia Smith, Indiana Univ, Indianapolis, IN; Sunit Singla, Univ of Illinois at Chicago, Chicago, IL; Roberto F Machado, Indiana Univ, Indianapolis, IN

4:30 PM

Board # 2284

BMPR2 **Mutation, an Other Evidence That Cancer and Pulmonary Hypertension Can Be Linked Together**

**Valerie Nadeau** , Eve Tremblay, Benoit Ranchoux, Marie-Claude Lampron, Quebec Heart and Lung institute, Quebec, QC, Canada; Frederic Perros, INSERM U999, Le Plessis Robinson, France; Pierre Hélie, Veterinary Medecine, St-Hyacinthe, QC, Canada; Roxane Paulin, Olivier Boucherat, Steeve Provencher, Sebastien Bonnet, Quebec Heart and Lung institute, Quebec, QC, Canada

4:30 PM

Board # 2285

Coronary Artery Remodeling Contributes to Right Ventricular Failure in Pulmonary Arterial Hypertension Patients

**Sandra Martineau** , Valerie Nadeau, Junichi Omura, Karima Habbout, Sandra Breuils-Bonnet, Eve Tremblay, Mark Orcholski, Roxane Paulin, Steeve Provencher, Olivier Boucherat, Sebastien Bonnet, CRIUCPQ, Quebec, QC, Canada

4:30 PM

Board # 2286

Cavin-Caveolin System Associates With Pulmonary Hypertension by Regulating BMP/Smad Signaling

**Shinya Tomita** , Naohiko Nakanishi, Takehiro Ogata, Yumika Tsuji, Akira Sakamoto, Yusuke Higuchi, Satoaki Matoba, Kyoto Prefectural Univ of Med, Kyoto, Japan

4:30 PM

Board # 2288

Biased Relaxin-RXFP1 Agonist ML290 Attenuates the Development of Pulmonary Hypertension

**Peiran Yang** , Lai-Ming Yung, Brigham and Women's Hosp / Harvard Medical Sch, Boston, MA; Courtney B Myhr, Florida Intl Univ, Miami, FL; Stephanie S Kim, Zachary M Augur, Brigham and Women's Hosp / Harvard Medical Sch, Boston, MA; Christopher VanDeusen, Omdana Therapeutics, Hopkinton, MA; Geoffrey A Bocobo, Teresa Dinter, Brigham and Women's Hosp / Harvard Medical Sch, Boston, MA; Jean Cavallo, David Chain, Shannon C Dwyer, Sanofi, Paris, France; Mark Southwood, ‎Papworth Hosp NHS Fndn Trust, Cambridge, United Kingdom; Zhiqiang Jia, Genzyme Corp, Framingham, MA; Nicholas W Morrell, Univ of Cambridge, Cambridge, MA; Stephane C Illiano, Sanofi-Aventis, Chilly-Mazarin, France; Marc Ferrer, Kenneth J Wilson, Noel Southall, Philip E Sanderson, Natl Insts of Health, Rockville, MD; Irina U Agoulnik, Florida Intl Univ, Miami, FL; Juan J Marugan, Natl Insts of Health, Rockville, MD; Alexander I Agoulnik, Florida Intl Univ, Miami, FL; Paul B Yu, Brigham and Women's Hosp, Boston, MA

4:30 PM

Board # 2289

Wistar: Han Rats Are Not All the Same. An RNAseq Approach to Access Supplier Differences in the Monocrotaline Model of Pulmonary Arterial Hypertension (PAH)

Vania Batalha, Eduardo Moura, Cristina Costa, Filipa Sousa, Maria-Joao Bonifacio, **Patricio Soares-da-Silva** , Bial, Portela and Cia, Coronado, Portugal

4:30 PM

Board # 2290

Xav939 Attenuates Pulmonary Arterial Hypertension by Reducing Pulmonary Artery Smooth Muscle Cell Proliferation

Dan Li, Xin Peng, **Wei Huang** , Chongqing Medical Univ, Chongqing, China

4:30 PM

Board # 2291

Mechanical Forces Alter Endothelin-1 Signaling: Comparative Ovine Models of Congenital Heart Disease

Rebecca Johnson Kameny, Univ California San Francisco, San Francisco, CA; Terry Zhu, Jason Boehme, UCSF, San Francisco, CA; Gary Raff, Univ California Davis, Davis, CA; Juan Lasheras, Antoni De Herreros, Univ California San Diego, La Jolla, CA; Stephen Black, Univ of Arizona, Tucson, AZ; Emin Maltepe, Sanjeev Datar, UCSF, San Francisco, CA; **Jeffrey R Fineman** , Univ California San Francisco, San Francisco, CA

4:30 PM

Board # 2292

Overexpression of TIFA in Patients With Pulmonary Arterial Hypertension

**Hao-Chih Chang** , Taipei Veterans General Hosp, Taipei City, Taiwan; Shih-Hsien Sung, Taipei Veterans General Hosp, Natl Yang Ming Univ, Taipei, Taiwan

4:30 PM

Poster Professor

Laura Elizabeth Fredenburgh, Boston, MA

4:30 PM

Board # 2293

Quarter or Safer Dose Thrombolysis in Submassive Pulmonary Embolism

Mohsen Sharifi, Arizona Cardiovascular Consultants and Vein Clinic, A.T.Still Univ, Mesa, AZ; Kaveh Karandish, Arizona Cardiovascular Consultants and Vein Clinic, Mesa, AZ; **Bethany Schroeder** , Arizona Cardiovascular Consultants and Vein Clinic, Mesa, AZ; Tushita Verma, A.T.Still Univ, Mesa, AZ

4:30 PM

Board # 2294

Association Between Tidal Volume and Outcomes in Patients Undergoing Mechanical Ventilation in the Cardiac Intensive Care Unit: Insights From the Medical Information Mart for Intensive Care (MIMIC-III) Database

**Carlos L Alviar** , New York Univ, New York, NY; Albert Y Lui, New York Univ Sch of Med, New York, NY; Leonid Garber, New York Univ Langone Health, New York, NY; Christopher Cosgriff, Jordan Poles, New York Univ Medical Sch, New York, NY; Vincent J Major, New York Univ Langone Health, New York, NY; Marie Charpignon, MIT, Cambridge, MA; Leo A Celi, Beth Israel Deaconess Medical Ctr, Boston, MA; Sean Van Diepen, Univ of Alberta, Edmonton, AB, Canada; Nathaniel Smilowitz, NYU Sch of Med, New York, NY

4:30 PM

Board # 2295

BMI1 Plays a Critical Role in Hyperoxia-Induced Acute Lung Injury

**Helena Hernandez-Cuervo** , Ramani Soundararajan, Sahebgowda Patil, Matthew Alleyn, Mason Breitzig, Univ of South Florida, Tampa, FL; Venkata Narala, Yogi Vemana Univ, Kadapa, India; Lakshmi Galam, Richard Lockey, Narasaiah Kolliputi, Univ of South Florida, Tampa, FL

# Abstract Poster Session

## HY.APS.03 - Hypertension and Heart Failure

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2165

A New Right Bundle Branch Block in Hypertensive Patients on Doxazosin Mediates Congestive Heart Failure: The ALLHAT Study

Ashley Wirth, Oregon Health and Science Universit, Portland, OR; Suzanne Oparil, Univ of Alabama at Birmingham, Birmingham, AL; Barry R Davis, Univ of Texas Sch Pub Hlth, Sugar Land, TX; **Larisa G Tereshchenko** , Oregon Health and Science Universit, Portland, OR

4:30 PM

Board # 2166

Significance of Systolic Blood Pressure on the Progression of Coronary Atherosclerosis in Subjects With Low Cardiovascular Risk

**Ki-Bum Won** , Ulsan Univ Hosp, Ulsan, Korea, Republic of; Ran Heo, Severance Cardiovascular Hosp, Seoul, Korea, Republic of; Byoung Kwon Lee, Gangnam Severance Hosp, Seoul; Sang-Eun Lee, Severance Cardiovascular Hosp, Seoul, Korea, Republic of; Asim Rizvi, Mayo Clinic, Rochester, MN; Fay Y Lin, Weill-Cornell Medical Ctr, New York City, NY; Martin Hadamitzky, Deutsches Herzzentrum Muenchen, Munich; Yong-Jin Kim, Seoul Natl Univ Hosp, Seoul; Matthew J Budoff, Los Angeles Biomedical Researc, Torrance, CA; Ilan Gottlieb, Johns Hopkins, Baltimore, MD; Eun Ju Chun, Bundang Seoul Natl Univ Hosp, Seongnam-Si, Korea, Republic of; Filippo Cademartiri, Erasmus Medical Ctr, Rotterdam; Jonathon Leipsic, UBC, Vancouver, BC, Canada; Sanghoon Shin, Nhis Ilsan Hosp, Gyeonggi-do, Korea, Republic of; Jung Hyun Choi, Pusan Natl Univ Hosp, Busan, Korea, Republic of; Renu Virmani, CV Path Inst Inc, Gaithersburg, MD; Habib Samady, Emory Univ Sch of Med, Atlanta, GA; Kavitha M Chinnaiyan, William Beaumont Hosp, Plymouth, MI; Gilbert Raff, William Beaumont Hosp, Royal Oak, MI; Peter H Stone, Brigham Womens Hosp, Boston, MA; Daniel Berman, -, Los Angeles, CA; Jagat Narula, Icahn Sch Med at Mount Sina, New York, NY; Leslee J Shaw, Emory Univ, Atlanta, GA; Jeroen J Bax, Leids Univ Medisch Centrum, Leiden, United Kingdom; James K Min, Weill Cornell Medical Coll, New York, NY; Hyuk-Jae Chang, Yonsei Univ Severance Hosp, Seoul, Korea, Republic of

4:30 PM

Board # 2167

Morning Surge in Blood Pressure as a Predictor of Worsening Heart Failure in Heart Failure With Reduced Ejection Fraction

**Takahiro Komori** , Satoshi Hoshide, Kazuomi Kario, Jichi Medical Univ, Tochigi-Ken, Japan

4:30 PM

Board # 2168

Associations of Irs-1 Genetic Polymorphism With the State of Vascular Wall and the Severity of Insulin Resistance in Hypertensive Patients Without Type 2 Diabetes

**Anna Shalimova** , Galyna Fadieienko, Olena Kolesnikova, Government Inst "L.T. Malaya Therapy Natl Inst of the Natl Acad of Medical Sciences of Ukraine", Kharkiv, Ukraine

4:30 PM

Board # 2169

Prevalence of Hypertension Based on 2017 American Heart Association Guidelines and Its Risk Factors in Urban And Rural Communities in India

**Mohan Thanikachalam** , Tufts Univ Sch of Med, Boston, MA; Sadagopan Thanikachalam, Sri Ramachandra Univ, Porur, India; Kevin Lane, Boston Univ, Boston, MA

4:30 PM

Board # 2170

Clinical Impact of Postoffice Clinic Blood Pressure Comparison With Automated Office Blood Pressure

**Woonggil Choi** , Konkuk Univ Chungju Hosp, Chungju, Korea, Republic of

4:30 PM

Board # 2171

Isolated Systolic Hypertension and the New Guidelines: A Unique Relationship Between Systolic Blood Pressure and Heart Rate

**Maria Carolina Delgado-Lelievre** , Jeffrey J Goldberger, Univ of Miami Medical Sch, Miami, FL

4:30 PM

Board # 2172

Are Angiotensin - (1-7) and Alamandine Biomarkers of Heart Ischemia?

Anna C Stein, Luiz Henrique Santana, Bruno Lauda, Barbara de Paula, Diana Russo, Charles Stefani, Paulo R Schvartzman, Milton Kalil, David Saitovitch, Mauricio Lutzky, Renato Eick, Daniel Sganzerl, Moinhos de Vento Hosp, Porto Alegre, Brazil; Kátia De Angelis, Univ Federal de São Paulo (UNIFESP), Sao Paulo, Brazil; Robson A Santos, UFMG, Belo Horizonte, Brazil; **Maria Claudia C Irigoyen** , Insto do Coracao (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, Univ de Sao Paulo, Sao Paulo, Brazil

4:30 PM

Board # 2173

The Empathy Building Resource Guide: A Tool to Enhance Clinical Practice and Patient-Provider Relationships in Hypertension Care

**Tiffany L. Young** , Lisa Quarles, Alicia Bilheimer, Adina Black, Mary E. Grewe, Lori Carter-Edwards, UNC Chapel Hill, Chapel Hill, NC

4:30 PM

Board # 2174

Blood Pressure Response to an Isometric Contraction Predicts Left Ventricular Hypertrophy

**Andreas Pittaras** , Mediton Medical Ctr, Athens, Greece; Peter F Kokkinos, Veteran S Affairs Medical Ctr, Annapolis, MD; Michael Doumas, Aristotle Univ of Thessalonik, Thessaloniki; Immanuel Samuel, VAMC, Washington, DC; Haralampos Grassos, Mediton Medical Ctr, Athens, Greece; Manolis Kallistratos, Asklepeion General Hosp, Athens, Greece; Leonidas Poulimenos, Asclepeion Hosp, Athens, Greece; Georgia Pyriovoli, Dimitrios Gourlis, Mediton Medical Ctr, Athens, Greece; Athanasios Manolis, Asclepeion Hosp, Athens, Greece; Konstantinos Imprialos, IPPOKRATION HOSPITAL, Thessaloniki; Konstantinos Stavropoulos, VAMC, Georgetown Univ, Thessaloniki; Charles Faselis, VAMC, Washington, DC

4:30 PM

Poster Professor

Hua Zhu, Columbus, OH

# Abstract Poster Session

## IM.APS.06 - Imaging of Catheter-Based Intervention

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 4200

Microvascular Angina is More Frequently Associated With Microvascular Spasm Than With Impaired Microvascular Vasodilator Capacity

**Andreas Seitz** , Giancarlo Pirozzolo, Valeria Martínez Pereyra, Klaus Storm, Alexander Becker, Udo Sechtem, Raffi Bekeredjian, Peter Ong, Robert-Bosch-Krankenhaus, Stuttgart, Germany

4:30 PM

Board # 4201

Ten-Year Clinical Outcomes of Intermediate Coronary Lesion; Prognosis and Predictors of Major Adverse Cardiovascular Events

Jang-Ho Bae, Konyang Univ Hosp, Daejeon, Korea, Republic of; Michel T Corban, Mayo Clinic, Rochester, MN; **Young Hoon Seo** , Konyang Univ Hosp, Daejeon, Korea, Republic of; Taewon Kim, Gahyeong Lee, Konyang Univ, Daejeon, Korea, Republic of; Charanjit Rihal, Amir Lerman, Mayo Clinic, Rochester, MN

4:30 PM

Board # 4202

Achilles Tendon Xanthoma is Associated With Lipid-Rich Vulnerable Plaque in Patients Without Diagnosed Familial Hypercholesterolemia Undergoing Percutaneous Coronary Intervention

**Hideki Kitahara** , Kan Saito, Takaaki Matsuoka, Chiba Univ Hosp, Chiba, Japan; Naoto Mori, Chiba Univ, Chiba, Japan; Kazuya Tateishi, Takashi Nakayama, Yoshihide Fujimoto, Chiba Univ Hosp, Chiba, Japan; Yoshio Kobayashi, Chiba Univ, Chiba, Japan

4:30 PM

Board # 4203

Machine Learning-Incorporated Intravascular Optical Coherence Tomography-Fluorescence Lifetime Imaging (OCT-FLIm) Provides Automated and Comprehensive Structural-Biochemical Characterization of Coronary Atherosclerotic Plaques

**Sunwon Kim** , Korea Univ Ansan Hosp, Ansan, Korea, Republic of; Hyeong Soo Nam, Hanyang Univ, Seoul, Korea, Republic of; Woojae Kang, KAIST, Daejeon, Korea, Republic of; Joon Woo Song, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Jeongmoo Han, Min Woo Lee, Hanyang Univ, Seoul, Korea, Republic of; Hyun-Sang Park, Wang-Yuhl Oh, Hongki Yoo, KAIST, Daejeon, Korea, Republic of; Jin Won Kim, Korea Univ Guro Hosp, Seoul, Korea, Republic of

4:30 PM

Board # 4204

Effects of the Adjunctive N-3 Polyunsaturated Fatty Acid Therapy to Strong Statin on Vascular Healing Process in Patients With Acute Coronary Syndrome: An Optical Coherence Tomography Study

**Yoko Kita** , Nara Medical Univ, Kashihara, Nara, Japan; Makoto Watanabe, Nara Medical Univ, Kashihara Nara, Japan; Satoshi Okayama, Nara Medical Univ, Kashihara, Nara, Japan; Daisuke Kamon, Nara Medical Univ, Kashihara, Japan; Tomoya Ueda, Nara Medical Univ, Nara, Japan; Tsunenari Soeda, Nara Medical Univ, Kashihara, Japan; Hiroyuki Okura, Gifu Univ Sch of Med, Gifu, Japan; Shiro Uemura, Kawasaki Medical Sch, Kurashiki, Japan; Yoshihiko Saito, Nara Medical Univ, Kashihara, Japan

4:30 PM

Board # 4205

Feasibility of IVUS-Derived FFR as a Novel Technique to Estimate Functional Severity of Coronary Stenosis: Systematic Evaluation of Thresholds to Determine Diseased Segment

**Kuninobu Kashiyama** , Stanford Univ, Stanford, CA; Shinjo Sonoda, Univ of Occupational and Environmental Health, Kitakyushu, Japan; Kensuke Matsushita, Yokohama City Univ Medical Ce, Yokohama, Japan; Kozo Okada, Yokohama City Univ Med Ctr, Yokohama, Japan; Kiyoshi Hibi, Yokohama, Yokohama, Japan; Kazuo Kimura, Yokohama City Univ Medical Ce, Yokohama, Japan; Brooke Hollak, Alan C Yeung, Paul G Yock, Stanford Univ, Stanford, CA; Peter Fitzgerald, Stanford Univ Sch Med, Stanford, CA; Yasuhiro Honda, Stanford Univ, Stanford, CA

4:30 PM

Board # 4206

Do Fractional Flow Reserve and Instantaneous Wave Free Ratio Correlate With Exercise Coronary Physiology?

**Matthew Ryan** , Bhavik Modi, Haseeb Rahman, Rupert Williams, Satpal Arri, Kaleab N Asrress, Matthew Lumley, Howard Ellis, Brian Clapp, Michael Marber, Simon R Redwood, Divaka Perera, King's Coll London, London, United Kingdom

4:30 PM

Board # 4207

In vivo Tissue Characteristics of Plaque Erosion: Analysis by Integrated Backscatter Intravascular Ultrasound

**Hirofumi Ohashi** , Aichi Medical Univ, Nagakute, Japan; Hirohiko Ando, Aichi Medical Univ, Aichi, Japan; Hiroaki Takashima, Katsuhisa Waseda, Yusuke Nakano, Sakurai Shinichiro, Akihiro Suzuki, Kazuhiro Naito, Aichi Medical Univ, Nagakute, Japan; Hiroaki Sawada, Aichi Medical Univ, Nagoya, Japan; Masanobu Fjimoto, Masahiro Shimoda, Atomu Tajima, Tetsuya Amano, Aichi Medical Univ, Nagakute, Japan

4:30 PM

Board # 4208

Mechanisms of Slow/No-Reflow Phenomenon During Percutaneous Coronary Intervention: An Intravascular Ultrasound Study

**Yasuhisa Nakao** , Shinji Inaba, Takumi Sumimoto, Kitaishikai Hosp, Ehime, Japan; Shuntaro Ikeda, Ehime Univ Graduate Sch of Med, Ehime, Japan; Makoto Saito, Kitaishikai Hosp, Ehime, Japan; Osamu Yamaguchi, Ehime Univ Graduate Sch of Med, Ehime, Japan

4:30 PM

Board # 4209

Cold Ambient Temperature and Increased Plaque Rupture Are Linked by Cholesterol Crystallization

**Yosuke Katayama** , Atsushi Tanaka, Takahiro Nishi, Kosei Terada, Hiroki Emori, Daisuke Higashioka, Mao Yokoyama, Teruaki Wada, Masahiro Takahata, Wakayama Medical Univ, Wakayama, Japan; Manabu Kashiwagi, Wakayama Medical Univ, Wakayama City, Japan; Kunihiro Shimamura, Yasutsugu Shiono, Akio Kuroi, Yoshiki Matsuo, Yasushi Ino, Takashi Kubo, Takeshi Hozumi, Takashi Akasaka, Wakayama Medical Univ, Wakayama, Japan

4:30 PM

Poster Professor

Micaela Iantorno, Potomac, MD

# Abstract Poster Session

## HT.APS.03 - Improving Quality of Care

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Poster Professor

Ike Okwuosa, Chicago, IL

4:30 PM

Board # 3224

Continuous Automated Medical Record-Based Detection of Possible Familial Hypercholesterolemia

**Willem A Bax** , Shari Pepplinkhuizen, Northwest Clinics, Alkmaar, Netherlands; Rutger Vink, Bas Groot, ChipSoft, Amsterdam, Netherlands; Jan H Cornel, Northwest Clinics, Alkmaar, Netherlands

4:30 PM

Board # 3225

An Innovative Application of Artificial Intelligence Techniques and Machine Learning in Diagnostic Evaluation of Pulmonary Hypertension

**Demi A Adedinsewo** , Elizabeth Lesser, Mohamad H Yamani, Rickey Carter, Mayo Clinic, Jacksonville, FL

4:30 PM

Board # 3226

Association Between Hospital Frequency of Resuscitation Training and Resuscitation Outcomes for Patients With In-hospital Cardiac Arrest

**Firas Al Badarin** , Saint Lukes Mid America Heart Ins, Kansas City, MO; Brahmajee Kartik Nallamothu, Univ Michigan Health System, Ann Arbor, MI; Brad Trumpower, Univ of Michigan, Ann Arbor, MI; Marci Kennedy, Saint Lukes Mid America Heart Ins, Kansas city, MO; Khaja Chinnakondepalli, St. Luke's Mid-America Heart Inst, Kansas City, MO; Vittal Hijjaji, Saint Lukes Mid America Heart Ins, Kansas City, MO; Ali Malik, Saint Luke's MAHI, Kansas City, MO; Yuanyuan Tang, Saint Lukes Mid America Heart Ins, kansas city, MO; Paul Chan, Saint Lukes Hosp / MAHI, Kansas City, MO

4:30 PM

Board # 3227

In-vitro Testing of 3D-Printed Mitral Valves With Phantom Mitral Annular Calcification

**Philip C Wiener** , Einstein Medical Ctr Philadelphia, Philadelphia, PA; Ahmed Darwish, Concordia Univ, Montreal, QC, Canada; Evan Friend, Einstein Medical Ctr Philadelphia, Philadelphia, PA; Lyes Kadem, Concordia Univ, Montreal, QC, Canada; Gregg S Pressman, Einstein Cardiology Assoc, Philadelphia, PA

4:30 PM

Board # 3228

Validation of Non-invasive Cardiac System (NICaS) Derived Stroke Volume With Cardiac Magnetic Resonance

Pedram Hassan-Tash, Umar Ismail, Gurkirat Chana, Iain Kirkpatrick, Davinder S Jassal, Brett Hiebert, St Boniface Hosp, Winnipeg, MB, Canada; Amir Ravandi, St Boniface Hosp & the Univ of Manitoba, Winnipeg, MB, Canada; Malek Kass, **Ashish H Shah** , St Boniface Hosp, Winnipeg, MB, Canada

4:30 PM

Board # 3229

Resource Allocation for Pediatric Cardiac Surgery

**Devyani Chowdhury** , Cardiology Care Children, Lancaster, PA; Kimberlee Gauvreau, Boston Children's Hosp, Boston, MA; Fred Eenennaam, Decision Inst, Amsterdam, Netherlands; Kevin Strauss, Clinic for Special Children, Strasburg, PA; Kathy J Jenkins, Boston Children's Hosp, Boston, MA

4:30 PM

Board # 3230

Readmission After Discharge Against Medical Advice for Persons With Opioid-Associated Infective Endocarditis

**Asher J Schranz** , Univ of North Carolina, Chapel Hill, NC; Li-Tzy Wu, Duke Univ, Durham, NC; David Wohl, David L Rosen, Univ of North Carolina, Chapel Hill, NC

4:30 PM

Board # 3231

Documentation of Shared Decision Making Around Primary Prevention Defibrillator Implantations

**Amr F Barakat** , Univ of Pittsburgh Medical Ctr, pittsburgh, PA; Anum Asif, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Ana Inashvili, UPMC, Pittsburgh, PA; Libby Szeto, Univ of Pittsburgh, Newark, CA; Ahmed Noor, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Alvin Thalappillil, Shubash Adhikari, Univ of Pittsburgh Medical Ctr, pittsburgh, PA; Shumail Fatima, Univ of Pittsburgh Medical Ctr, Monroeville, PA; Deepak Kumar Pasupula, Univ. of Pittsburgh Medical Ctr, Pittsburgh, PA; Shahzad Ahmad, Univ of Pittsburgh Medical Ctr, pittsburgh, PA; Don Mathew, UPMC, Monroeville, PA; Aditya Bhonsale, Univ of Pittsburgh Medical Ctr, pittsburgh, PA; Krishna Kancharla, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Norman C Wang, Univ of Pittsburgh, Pittsburgh, PA; Sandeep Jain, Univ Pittsburgh, Wexford, PA; N A Estes III, Samir Saba, UPMC, Pittsburgh, PA

4:30 PM

Board # 3232

Subjective Preferences and Goal Among the Patients Treated With Transaortic Valvular Replacement

Kohei Sugiura, Keio Univ Sch of Med, Tokyo, Japan; **Takashi Kohno** , Kyorin Univ Sch of Med, Tokyo, Japan; Kentaro Hayashida, Tetsuya Saito, Hiromu Hase, Nobuhiro Yoshijima, Hikaru Tsuruta, Daisuke Fujisawa, Yuji Itabashi, Shun Kohsaka, Keiichi Fukuda, Keio Univ Sch of Med, Tokyo, Japan

4:30 PM

Board # 3233

Healthcare Access to TAVR Procedures by Population Density: A Focus on Healthcare Disparity in Florida

**Abdulla A Damluji** , Inova Heart and Vascular Inst, Falls Church, VA; Richard Epstein, Univ of Miami, Miami, FL; Mauro Moscucci, FDA, Baltimore, MD; Stefan Rayer, Ying Wang, Univ of Florida, Gainsville, FL; Mauricio Gabriel Cohen, Univ of Miami, Miami, FL; Jon Rodney Resar, Johns Hopkins, Baltimore, Maryland, MD; David J Cohen, Saint Luke's Mid America Heart Inst, Kansas City, MO; Christopher O'Connor, Inova Heart and Vascular Inst, Falls Church, VA; Wayne B. Batchelor, St Michael's Hosp Cardiology Dept, Tallahassee, FL; Michael Fabbro, Univ of Miami, Philadelphia, PA

# Abstract Poster Session

## AT.APS.09 - Innovative Approaches to Assess (Micro)Vascular Contributions to Disease

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 1106

A Novel Low-Cost Cellular Functional Assay Reveals a Potential Role for Piezo1 in Hyperglycemia Induced Microcirculatory Disorders

**Wandi Zhu** , Brigham and Women's Hosp, Boston, MA; Manu Beerens, BWH - Harvard Medical Sch, Boston, MA; Tuomas O Kiviniemi, Turku Univ Hosp and Brigham and Women's Hosp, Turku, Finland; Evan Wilson, Rahul C Deo, Calum A Macrae, Brigham and Women's Hosp, Boston, MA

4:30 PM

Board # 1107

Polarized Macrophages in the Perivascular Adipose Tissue Were Correlated With Atherosclerotic Plaque Components in Coronary Arteries: An Autopsy Study

**Daniela S Farias-Itao** , Carlos A Pasqualucci, Univ of Sao Paulo Medical Sch, Sao Paulo, Brazil; Renato A Andrade, Federal Inst of Education, Science and Technology of Sao Paulo, Sao Paulo, Brazil; Luiz Fernando F Silva, Univ of Sao Paulo Medical Sch, Sao Paulo, Brazil; Alexandre B Campo, Federal Inst of Education, Science and Technology of Sao Paulo, Sao Paulo, Brazil; Claudia K Suemoto, Univ of Sao Paulo Medical Sch, Sao Paulo, Brazil

4:30 PM

Board # 1108

Novel Method for Assessing Leukocyte Activation in Whole Blood

**Takanori Yasu** , Riha Shimizu, Dokkyo Medical Univ Nikko Medical Ctr, Nikko, Japan; Hirotsugu Fukuda, Dokkyo Medical Univ, Mibu, Japan; Yuji Kikuchi, Kikuchi Microtechnology Inst, Ryugasaki, Japan; Yuki Nakatani, Dokkyo Medical Univ Nikko Medical Ctr, Nikko, Japan

4:30 PM

Board # 1109

Ultra-High Sensitivity Cardiac Troponin I Elevation, Myocardial Malperfusion and Diastolic Dysfunction in Women With Ischemia and No Obstructive Coronary Artery Disease

**Odayme Quesada** , Omeed Elboudwarej, Cedar Sinai Medical Ctr, Los Angeles, CA; Michael D Nelson, UT Arlington, Mansfield, TX; Mitra Mastali, Cedars Sinai Medical Ctr, Beverly Hills, CA; Janet Wei, Cedars-Sinai Medical Ctr, Los Angeles, CA; Ahmed Al-Badri, Emory Clinical Cardiovascular Res Inst, Atlanta, GA; Nissi Suppogu, Cedar Sinai Medical Ctr, Los Angeles, CA; Haider Aldiwani, Cedars Sinai, Los Angeles, CA; Puja K Mehta, Emory Univ, Atlanta, GA; Chrisandra Shufelt, Cedars-Sinai Medical Ctr, Los Angeles, CA; Galen Cook-Wiens, Jenna Maughan, Daniel Berman, Cedar Sinai Medical Ctr, Los Angeles, CA; Louise Elizabeth Jane Thomson, Cedars Sinai Medical Ctr, Los Angeles, CA; Carl Pepine, Univ of Florida, Gainesville, FL; Jennifer E Van Eyk, Noel Bairey Merz, Cedar Sinai Medical Ctr, Los Angeles, CA

4:30 PM

Board # 1110

Directly Reprogrammed Endothelial Cells from Human Dermal Fibroblast Encapsulated With Nanomatrix Gel Improved Cardiac Function After Myocardial Infarction by Increasing Microvasculature

**Dandan Chen** , Emory Univ SOM, Atlanta, GA; Sangho Lee, Emory Univ, Atlanta, GA; Sangsung Kim, Han Li, Emory Univ SOM, Atlanta, GA; Ho-wook Jun, U of Alabama at Birmingham, Birmingham, AL; Young-sup Yoon, Emory Univ Sch Med, Atlanta, GA

4:30 PM

Board # 1111

Selective Roles of Endothelial Prostaglandins in the Regulation of Cerebral and Renal Microarteriolar Contractions to Angiotensin II

**Christopher S Wilcox** , LIngli Li, Georgetown Univ Div of Nephrology, Washington, DC; Enyin Lai, Georgetown Univ, Washington, DC

4:30 PM

Board # 1112

Low-intensity Pulsed Ultrasound (LIPUS) Therapy Ameliorates DES-induced Coronary Hyperconstricting Responses Through Its Anti-inflammatory Effects in Pigs in vivo -A Novel Non-invasive Therapy for Coronary Inflammation-

**Tasuku Watanabe** , Yasuharu Matsumoto, Tohoku Univ Graduate Sch of Med, Aoba-ku, Sendai, Japan; Hirokazu Amamizu, Akita Cerebrospinal and Cardiovascular Ctr, Akita, Japan; Susumu Morosawa, Jun Sugisawa, Satoshi Tsuchiya, Kazuma Ohyama, Kensuke Nishimiya, Hiroaki Shimokawa, Tohoku Univ Graduate Sch of Med, Aoba-ku, Sendai, Japan

4:30 PM

Board # 1113

Beneficial Effects of Drug-eluting Stents With Bioabsorbable Polymer Coating on Coronary Hyperconstricting Responses and Adventitial Vasa Vasorum Formation in Patients With Angina Pectoris -An Intracoronary OCT Study-

Kiyoto Mitsuishi, **Kensuke Nishimiya** , Yasuharu Matsumoto, Tasuku Watanabe, Satoshi Tsuchiya, Jun Sugisawa, Koichi Satoh, Akira Suda, Tomohiko Shindo, Shigeo Godo, Shohei Ikeda, Kiyotaka Hao, Yoku Kikuchi, Jun Takahashi, Hiroaki Shimokawa, Tohoku Univ Graduate Sch of Med, Sendai, Japan

4:30 PM

Board # 1114

Adenosine-Induced Hypotension and Submaximal Vasodilation Lead to Overestimation of the Impact of Microcirculatory Dysfunction on Absolute Coronary Flow Reserve

**Brian R Weil** , Adebola Ogunsakin, Beth A Palka, John M Canty, Univ at Buffalo, Buffalo, NY

4:30 PM

Board # 1115

Angina, Myocardial Perfusion, and Left Ventricular Structure Improve in Women With No Obstructive Coronary Artery Disease at 1-year Follow-Up: Findings From the Women's Ischemia Syndrome Coronary Vascular Dysfunction Study

**Odayme Quesada** , Melody Hermel, Cedar Sinai Medical Ctr, Los Angeles, CA; Haider Aldiwani, Cedars Sinai, Los Angeles, CA; Nissi Suppogu, Cedar Sinai Medical Ctr, Los Angeles, CA; Chrisandra Shufelt, Cedars-Sinai Medical Ctr, Los Angeles, CA; Galen Cook-Wiens, Jenna Maughan, Cedar Sinai Medical Ctr, Los Angeles, CA; Puja K Mehta, Emory Univ, Atlanta, GA; Daniel Berman, -, Los Angeles, CA; Louise Elizabeth Jane Thomson, Cedars Sinai Medical Ctr, Los Angeles, CA; Carl Pepine, Univ of Florida, Gainesville, FL; Noel Bairey Merz, Cedar Sinai Medical Ctr, Los Angeles, CA; Janet Wei, Cedars-Sinai Medical Ctr, Los Angeles, CA

# Abstract Poster Session

## MP.APS.02 - Integration of Lifestyle, Treatment, and Disease

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 1160

Impact of Lowering LDL-C With Evolocumab on Everyday Cognition in Participants From the FOURIER Trial

**Baris Gencer** , TIMI Study Group, Boston, MA; François Mach, Univ Hosp Geneva, Geneva, Switzerland; Jianping Guo, Kyungah Im, TIMI Study Group, Boston, MA; Andrea Ruzza, AMGEN, Thousand Oaks, CA; Huei Wang, AMGEN, Newbury Park, CA; Christopher Kurtz, 1 Amgen Ctr Drive, Thousand Oaks, CA; Terje Rolf Pedersen, Oslo Univ Hosp, Oslo, Norway; Anthony C Keech, NHMRC Clinical Trials Ctr, Camperdown Sydney, Australia; Brian Ott, Rhode Island Hosp, Providence, RI; Marc S Sabatine, Robert P Giugliano, TIMI Study Group, Boston, MA

4:30 PM

Board # 1161

Statin Use is Associated With Lower Mortality in Patients With Breast Cancer

**Ohad Oren** , Mayo Clinic, Rochester, MN; Eric H Yang, UCLA Medical Ctr, Culver City, CA; Thorvardur R Halfdanarson, Karen M Fischer, Diane E Grill, Stephen L Kopecky, Mayo Clinic, Rochester, MN

4:30 PM

Board # 1162

Establishing 30-year Expected Benefit Thresholds to Refine Statin Eligibility in Primary Prevention

**Fernando Cesena** , Viviane Valente, Hosp Israelita Albert Einstein, Sao Paulo, Brazil; Raul Santos, Univ of Sao Paulo Medical Sch Hosp, Sao Paulo, Brazil; Marcio S Bittencourt, Ficsae, Sao Paulo, Brazil

4:30 PM

Board # 1163

Higher Disialylated Apolipoprotein C-III Proteoform is Associated With Lower Plasma Triglycerides in Type 2 Diabetes

**Juraj Koska** , Phoenix VA Health Care System, Phoenix, AZ; Dobrin Nedelkov, Isoformix, Inc, Phoenix, AZ; Gideon Bahn, Hines CSP Coordinating Ctr, Hines, IL; Peter D Reaven, Phoenix VA Health Care System, Phoenix, AZ; VADT Investigators

4:30 PM

Board # 1164

Clusetered Myoblast Cell Injection Utilizing Cells Sheet Technology Augment Angiogenesis and Muscle Regeneration in a Mouse Model of Peripheral Artery Disease

**Keisuke Miyake** , Shigeru Miyagawa, Takashi Shibuya, Osaka Univ, Suita, Japan; Akima Harada, Osaka Univ, Osaka, Japan; Shusaku Maeda, Osaka Univ, Suita, Japan; Takayoshi Ueno, Osaka Univ Graduate Sch of Med, Suita, Japan; Toru Kuratani, Osaka Univ / CV Surgery, Osaka, Japan; Koichi Toda, Natl Cardiovascular Ctr, Kobe, Japan; Yoshiki Sawa, Osaka Univ, Osaka, Japan

4:30 PM

Board # 1165

Agreement Among Four Methods for Identifying Patients With Familial Hypercholesterolemia in a Large Healthcare System

**Michael P Dorsch** , Corey Lester, Univ of Michigan, Coll of Pharmacy, Ann Arbor, MI; Katie Mues, Amgen, Thousand Oaks, CA; Yuting Ding, Univ of Michigan, Coll of Pharmacy, Ann Arbor, MI; Keri L Monda, J Antonio G Lopez, AMGEN, Thousand Oaks, CA; Megan Joseph, Univ of Michigan, Frankel Cardiovascular Ctr, Ann Arbor, MI; Robert Brook, Univ of Michigan, Medical Sch, Ann Arbor, MI

4:30 PM

Board # 1166

Cost Effectiveness of Cascade Testing for Familial Hypercholesterolemia in the US: A Simulation Analysis

**Candace L Jackson** , Todd Huschka, Bijan J Borah, Katherine Agre, Magdi Zordok, Medhat Farwati, James Moriarty, Iftikhar J Kullo, Mayo Clinic, Rochester, MN

4:30 PM

Board # 1167

Effect of Alirocumab on Estimated Low-Density Lipoprotein Cholesterol Corrected for Lipoprotein (a) Cholesterol: Pooled Analysis From 5 ODYSSEY Phase 3 Studies

**Sotirios Tsimikas** , Univ California San Diego, La Jolla, CA; Jennifer G Robinson, Univ Iowa Coll Public Health, Iowa City, IA; Helen Li, Regeneron Pharmaceuticals, Tarrytown, NY; Marc K Israel, Regeneron, Basking Ridge, NJ; Catherine Domenger, Sanofi Val De Bievre, Gentilly, France; Daniel Gaudet, CMGC Univ De Montreal, Chicoutimi, QC, Canada

4:30 PM

Board # 1168

Effect of Evolocumab on Non-high-density Lipoprotein Cholesterol and Apolipoprotein B Levels: An Analysis of Double-blind and Open-label Extension Studies

**Peter P. Toth** , CGH Medical Ctr, Sterling, IL; Steven R Jones, The Johns Hopkins Univ, Baltimore, MD; Maria Laura Monsalvo, Amgen Inc., Thousand Oaks, CA; Mary Elliott-Davey, Amgen Ltd, Cambridge; J Antonio G Lopez, AMGEN, Thousand Oaks, CA; Maciej Banach, Medical Univ of Lodz, Lodz, Poland

4:30 PM

Poster Professor

Hagai Tavori, Portland, OR

4:30 PM

Board # 1169

TRIM2 **and** CREBRF **Are Novel Regulators of Angiogenic Functions in Human Coronary Artery Endothelial Cells**

**Nathan K.P. Wong** , SAHMRI, Adelaide, Australia; Emma Solly, SAHMRI, Adelaide, SA, Australia; Stephen Nicholls, Monash Health, Hyde Park, Australia; Peter Psaltis, SAHMRI, Adelaide, Australia; Martin K.C. Ng, Royal Prince Alfred Hosp, Camperdown, Australia; Christina A Bursill, Joanne Tsui Ming Tan, SAHMRI, Adelaide, SA, Australia

# Abstract Poster Session

## HY.APS.04 - Integrative Aspects of Clinical Hypertension

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2175

Sex-Dependent Association Between Day-By-Day Morning Blood Pressure Variability and Common Carotid Artery Intima-Media Thickness in the Japanese at High-Risk of Cardiovascular Disease

**Michiaki Nagai** , Hiroshima City ASA Hosp, Hiroshima, Japan; Satoshi Hoshide, JICHI Medical Univ, Shimotsuke, Japan; Kazuomi Kario, JICHI Medical Univ, Tochigi-ken, Japan

4:30 PM

Board # 2176

Abnormal Circadian Blood Pressure Rhythm is Associated With Cognitive Impairment in Not Only Elderly Patients but Also Young Patients With Heart Failure

**Takahiro Komori** , Jichi Medical Univ, Tochigi-ken, Japan; Satoshi Hoshide, JICHI MIDICAL UNIVERSITY, Shimotsuke, Japan; Kazuomi Kario, JICHI MEDICAL UNIVERSITY, Tochigi-ken, Japan

4:30 PM

Board # 2177

Evaluate The Incidence of Hypertension in Patients With Rheumatoid Arthritis Treated by Tnf Alpha Inhibitors

**Hetavi Mahida** , Ana Gubeladze, Jersey Shore Univ Medical Ctr, Neptune, NJ; Dawn M Calderon, Jersey Shore Univ Medical Ctr, Toms River, NJ

4:30 PM

Board # 2178

Implementation Of A Multifaceted Strategy For The Control Of Hypertension And Diabetes In Primary Care In A Low-income And Resource Constrained Region: Healthrise Brazil Teofilo Otoni Project

**Christiane C.r Cimini** , Univ Federal dos Vales do Jequitinhonha e Mucuri, Belo Horizonte, Brazil; Milena S Marcolino, João A.Q Oliveira, Junia X Maia, Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Vania S.O.A Pinto, Patrick W Endlich, Márcia M.O Lima, Lucas T Nogueira, Univ Federal dos Vales do Jequitinhonha e Mucuri, Belo Horizonte, Brazil; Thábata Q.V Sá, Leonardo B Ribeiro, Maria Cristina Paixão, Antonio L Ribeiro, Univ Federal de Minas Gerais, Belo Horizonte, Brazil

4:30 PM

Board # 2179

Clinical Utility of Pulse-transit-time for Continuous Blood Pressure Monitoring in Patient With Sleep Disordered Breathing

**Tomofumi Misaka** , Akiomi Yoshihisa, Yuko Niimura, Yusuke Kimishima, Yuki Kanno, Tetsuro Yokokawa, Takamasa Sato, Atsushi Kobayashi, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

4:30 PM

Board # 2180

A Functional Mri (resting State Functional Mri Rs-fmri) Highlights Altered Connections and Altered Functional Networks in Hypertensive Patients

**Lorenzo Carnevale** , Angelo Maffei, Alessandro landolfi, Giovanni Grillea, I.R.C.C.S. Neuromed, Pozzilli, Italy; Daniela Carnevale, Sapien Univ/I.R.C.C.S. Neuromed, Pozzilli, Italy; Giuseppe Lembo, IRCCS Neuromed, Pozzilli, Italy

4:30 PM

Board # 2181

Riser Pulse Rate Pattern Was Strongly Associated With Cardiac Damage and Cardiovascular Events:The Japan Morning Surge Home Blood Pressure (J-HOP) Study

**Hisaya Kobayashi** , Jichi Medical Univ Hosp, Shiomotsuke, Japan; Tomoyuki Kabutoya, Jichi Medical Univ, Shimotsuke Tochigi, Japan; Satoshi Hoshide, Jichi Medical Univ, Shimotsuke, Japan; Kazuomi Kario, Jichi Medical Univ, Tochigi-ken, Japan

4:30 PM

Board # 2182

The Trp Allele of the Gly460trp Polymorphism and the Urinary Sodium Potassium Ratio in Hypertensive and Normotensive Subjects

**Maria Carolina Delgado-Lelievre** , Univ of Miami Medical Sch, Doral, FL; David A Lelievre, Devine Savior Acad, Doral, FL; Antonio J Delgado, Univ of Pedro Valdivia Sch of Med, La Serena, Chile

4:30 PM

Board # 2183

Pulse Pressure is Associated With High Cardiovascular Mortality After Adjustment for Systolic Blood Pressure and Risk Factors

**William J. Kostis** , Rutgers Robert Wood Johnson Medical Sch, New Brunswick, NJ; Javier Cabrera, Rutgers Univ, Piscataway, NJ; Chun Pang Lin, John B Kostis, Rutgers Robert Wood Johnson Med Sch, New Brunswick, NJ

4:30 PM

Board # 2184

Use of Automated Self-administered24-hour (asa24®) Dietary Assessment Tool in Estimation of Magnesium Intake

Hamza Lodhi, UTSW Medical Ctr, Dallas, TX; **Ursa Bezan Petric** , Jere Mitchell, Scott A Smith, UT Southwestern Medical Ctr, Dallas, TX; Lona Sandon, UTSW Medical Ctr, Dallas, TX; Naim Maalouf, UT Southwestern Medical Ctr, Dallas, TX; Wanpen Vongpatanasin, Univ TX Southwestern Med, Dallas, TX

# Abstract Poster Session

## PH.APS.09 - Markers and Outcomes in Pulmonary Hypertension II

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2296

Systemic Arterial Pulsatility Index is Associated With Mortality in Pulmonary Arterial Hypertension

Sula Mazimba, Univ Virginia, Charlottesville, VA; Nora Tolbert, Charlottesville, VA; Comfort Elumogo, Olusola O Laja, Persey Bediako, Stafford Patrick, Univ Virginia, Charlottesville, VA; **Mwenya Mubanga** , Uppsala Univ, Uppsala, Sweden; Sthuthi David, UVA Health System, Charlottesville, VA; Steve N Noutong, Univ Virginia, Charlottesville, VA; Younghoon Kwon, Univ of Virginia, Charlottesville, VA; Andrew Mihalek, Univ Virginia, Charlottesville, VA; Nishaki M Mehta, Univ of Virginia, Charlottesville, VA; Kenneth C Bilchick, Univ of Virginia HS, Charlottesville, VA

4:30 PM

Board # 2297

Pulmonary Hypertension Subtypes and Mortality in Chronic Kidney Disease

**Daniel Edmonston** , Duke Univ, Durham, NC; Kishan S Parikh, Duke Univ Medical Ctr, Durham, NC; Sudarshan Rajagopal, Duke Univ Medical Ctr, Chapel Hill, NC; Linda K. Shaw, Duke Univ Medical Ctr, Durham, NC; Dennis Abraham, Alexander Grabner, Duke Univ, Durham, NC; Matthew A Sparks, Duke Univ Medical Ctr, Durham, NC; Myles Wolf, Duke Univ, Durham, NC

4:30 PM

Board # 2298

Experience of Three Years of Balloon Pulmonary Angioplasty in a Single Centre: Safety and Short Term Results

Massimiliano Palazzini, Inst of Cardiology, Univ of Bologna, Bologna, Italy; Francesco Saia, Inst of Cardiology - Univ of Bologna, Bologna, Italy; Enrico Gotti, Nevio Taglieri, **Fabio Dardi** , Elisa Zuffa, Alessandro De Lorenzis, Filippo Pasca, Daniele Guarino, Ilenia Magnani, Andrea Rinaldi, Alessandra Manes, Nazzareno Galiè, Inst of Cardiology, Univ of Bologna, Bologna, Italy

4:30 PM

Board # 2299

Pulmonary Arterial Hypertension: Rapid Sequential Combination Therapy With PDE5 Inhibitors and Endothelin Receptor Antagonists Substantially Improves Hemodynamics at Early Follow-up

**Tilmann T Kramer** , Daniel Dumitrescu, Felix Gerhardt, Phillip Nattmann, Christopher Hohmann, Stephan Baldus, Stephan Rosenkranz, Clinic III for Internal Med, Cologne, Germany

4:30 PM

Board # 2300

Endothelial Deficiency of Iron-sulfur Scaffolding Protein Nfu1 Drives Metabolic Dysfunction to Promote Pulmonary Hypertension

**Dror Perk** , Univ of Pittsburgh, Pittsburgh, PA; Miranda Kay Culley, Univ of Pittsburgh Som, Pittsburgh, PA; Qiujun Yu, Univ of Iowa Hosp, Iowa City, IA; Yi Yin Tai, Chen-Shan Julia Woodcock, Stephen Y Chan, Univ of Pittsburgh, Pittsburgh, PA

4:30 PM

Board # 2301

Crizotinib Exacerbates Sugen-Induced Pulmonary Arterial Hypertension

Charifa Awada, Laval Univ, Quebec, QC, Canada; Olivier Boucherat, IUCPQ Res Ctr, Quebec, QC, Canada; Steeve Provencher, Laval Univ; Sebastien Bonnet, Quebec Heart and Lung institute, Quebec, QC, Canada; **Francois Potus** , Queen's Univ, Kingston, ON, Canada

4:30 PM

Board # 2302

Increased Echocardiographic Pulmonary Vascular Resistance Predicts Progression of Pulmonary Hypertension in Connective Tissue Disease Patients With Borderline Pulmonary Hypertension

**Yoshiyuki Orihara** , Hyogo Coll of Med, Nishinomiya, Japan; Masanori Asakura, Hyogo Coll of Med, Hyogo, Japan; Yoshitaka Okuhara, Hyogo Coll of Med, Nishinomiya City, Japan; Yuki Matsumoto, Hyogo Coll of Med, Nishinomiya-shi, Japan; Masaharu Ishihara, Hyogo Coll of Med, Nishinomiya, Japan

4:30 PM

Board # 2303

Pulmonary Arterial Compliance Can Differentiate Exercise-Induced Pulmonary Hypertension Due to Pulmonary Vascular Disease versus Left-Heart Disease

**C. Danielle Hopkins** , John Wells, Stephen Mathai, Johns Hopkins Univ Sch of Med, Baltimore, MD; Ryan J Tedford, Medical Univ of South Carolina, Charleston, SC; Steven Hsu, Johns Hopkins Sch of Med, Baltimore, MD

4:30 PM

Board # 2304

In the Sugen/hypoxia Model of Murine Pulmonary Arterial Hypertension, While Absence of S100A1 Exacerbates Right Ventricular Dysfunction, RAGE Deficiency Confers Protection

**James N Tsoporis** , Krystyna Teichert-Kuliszewska, Jean-Francois Desjardins, Shehla Izhar, Thomas G Parker, St. Michael's Hosp, Toronto, ON, Canada

4:30 PM

Board # 2305

Efficacy and Safety of Pulmonary Vasodilators in the Patients With Eisenmenger Syndrome: A Meta-Analysis of Randomized Controlled Trials

Yulin Hou, **Wei Huang** , Chongqing Medical Univ, Chongqing, China

4:30 PM

Board # 2306

Current Definitions of Exercise-Induced Pulmonary Hypertension Lack Sensitivity in Detecting Abnormal Hemodynamics

**John A Wells IV** , Johns Hopkins Hosp, Baltimore, MD; C. Danielle Hopkins, Johns Hopkins Univ SOM, Baltimore, MD; Stephen Mathai, Johns Hopkins Hosp, Baltimore, MD; Ryan J Tedford, Medical Univ South Carolina, Charleston, SC; Steven Hsu, Johns Hopkins Hosp, Baltimore, MD

4:30 PM

Board # 2307

Evaluation of the Impact of an Echocardiographic Diagnosis of Pulmonary Hypertension on Patient Outcomes

**Ping Yu Xiong** , Jaff Zardasht, Christine D'Arsigny, Stephen L Archer, Thiwanka Wijerante, Queen's Univ, Kingston, ON, Canada

4:30 PM

Board # 2308

Assessment of the Pulmonary Arterial Remodeling and the Risk Stratification Score During Short-term Follow-up in Prevalent Pulmonary Arterial Hypertension Patients

**Enric Domingo** , Hosp Univri Vall d'Hebron, Barcelona, Spain; Juan C Grignola, Hosp de Clinicas, UdelaR, Montevideo, Uruguay; Alvaro Calabuig, Santiago Pérez Hoyos, Manuel López Messeguer, Antonio Roman, Hosp Univri Vall d'Hebron, Barcelona, Spain

4:30 PM

Board # 2309

Inhaled Iloprost for Vasoreactivity Assessment in Patients With Pulmonary Hypertension: Preliminary Results From the OVATION Study (NCT03044314)

**Jordan D Awerbach** , Phoenix Children's Hosp, Phoenix, AZ; Mouhammad Fathallah, Duke Univ Hosp, Durham, NC; John Serfas, Jhaymie Cappiello, Duke Univ, Durham, NC; Carlos Oberti, Cleveland Clinic, Cleveland, OH; Kishan S Parikh, Duke Univ Medical Ctr, Durham, NC; Fortin Terry, Sudar Rajagopal, Duke Univ Hosp, Durham, NC; Talal Dahhan, Duke Univ, Durham, NC; Richard Krasuski, Duke Univ Medical Ctr, Durham, NC

# Abstract Poster Session

## LF.APS.04 - Markers of Cardiovascular Health

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 3193

Air Pollution And Carotid Atherosclerosis In Coronary Artery Disease Patients

Basiliki Chara Mystakidi, Evangelos Oikonomou, Panagiotis Theofilis, Petros Fountoulakis, Margarita N Asimakopoulou, Nikolaos Barbaresos, Ioannis Giannarakis, Georgia Vogiatzi, Margenti Papakonstantinou, Sotiris Tsalamandris, George Lazaros, **Dimitris Tousoulis** , Hippokration General Hosp, Athens, Greece

4:30 PM

Board # 3194

Vascular Endothelial Growth Factor C and Mortality in Patients With Diabetes and Stable Coronary Heart Disease: From the ANOX Study

**Hiromichi Wada** , Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan; Masahiro Suzuki, Natl Hosp Organization Saitama Hosp, Wako, Japan; Morihiro Matsuda, Natl Hosp Organization Kure Medical Ctr and Chugoku Cancer Ctr, Kure, Japan; Yoichi Ajiro, Natl Hosp Organization Yokohama Medical Ctr, Yokohama, Japan; Tsuyoshi Shinozaki, Natl Hosp Organization Sendai Medical Ctr, Sendai, Japan; Satoru Sakagami, Natl Hosp Organization Kanazawa Medical Ctr, Kanazawa, Japan; Kazuya Yonezawa, Natl Hosp Organization Hakodate Natl Hosp, Hakodate, Japan; Masatoshi Shimizu, Natl Hosp Organization Kobe Medical Ctr, Kobe, Japan; Junichi Funada, Natl Hosp Organization Ehime Medical Ctr, Toon, Japan; Takashi Takenaka, Natl Hosp Organization Hokkaido Medical Ctr, Sapporo, Japan; Yukiko Morita, Natl Hosp Organization Sagamihara Natl Hosp, Sagamihara, Japan; Toshihiro Nakamura, Natl Hosp Organization Kyushu Medical Ctr, Fukuoka, Japan; Kazuteru Fujimoto, Natl Hosp Organization Kumamoto Medical Ctr, Kumamoto, Japan; Hiromi Matsubara, Natl Hosp Organization Okayama Medical Ctr, Okayama, Japan; Toru Kato, Natl Hosp Organization Tochigi Medical Ctr, Utsunomiya, Japan; Takashi Unoki, Daisuke Takagi, Kyohma Wada, Miyaka Wada, Moritake Iguchi, Nobutoyo Masunaga, Mitsuru Ishii, Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan; Kazuhiko Kotani, Jichi Medical Univ, Shimotsuke, Japan; Mitsuru Abe, Masaharu Akao, Koji Hasegawa, Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan

4:30 PM

Board # 3195

Red Cell Distribution Width Predicts Long-term Cardiovascular Outcomes in Patients With Stable Coronary Artery Disease

**Hideki Wada** , Juntendo Univ Shizuoka Hospit, Izunokuni Shizuoka, Japan; Tomotaka Dohi, Katsumi Miyauchi, Juntendo Univ, Tokyo, Japan; Ryota Nishio, Kentaro Yasuda, Juntendo Univ Shizuoka Hospit, Izunokuni Shizuoka, Japan; Mitsuhiro Takeuchi, Juntendo Univ Shizuoka Hosp, Shizuoka, Japan; Norihito Takahashi, Juntendo Univ, Bunkyo-Ku, Tokyo, Japan; Manabu Ogita, Juntendo Univ Shizuoka, Izunokuni, Japan; Satoru Suwa, Juntendo Univ Shizuoka Hosptal, Izunokuni, Japan; Hiroyuki Daida, Juntendo Univ, Tokyo, Japan

4:30 PM

Board # 3196

Epicardial Fat Volume is an Independent Predictor of Coronary Fatty Plaque Volume

**Maral Amangurbanova** , Bhavya Vemuri, Abdul Aziz A Asbeutah, Abdulaziz Malik, Beth Israel Deaconess Medical Ctr/ Harvard Medical Sch, Boston, MA; Jaya Kanduri, BIDMC, Boston, MA; Francine K Welty, Harvard Medical Sch, Brookline, MA

4:30 PM

Board # 3197

Impact of Non-alcoholic Fatty Liver Disease on Coronary High-risk Plaque Assessed by Coronary Computed Tomography and Its Long-term Prognosis

**Keishi Ichikawa** , Okayama Univ, Okayama-shi Okayama, Japan; Toru Miyoshi, Okayama Univ, Okayama, Japan; Takashi Miki, Okayama Univ, Okayama-city, Japan; Kazufumi Nakamura, Hiroshi Ito, Okayama Univ, Okayama, Japan

4:30 PM

Board # 3198

Effects of Diesel Exhaust Fumes Exposure on Vascular Wall Properties Inflammation and Endothelial Function

**Petros Fountoulakis** , 'Hippokration' Hosp, Natl and Kapodistrian Univ of Athens Medical Sch, Athens, Greece; Evangelos Oikonomou, Ippokratio Hosp, Ano Lanonisi, Greece; Sotiris Tsalamandris, 1rst Dept of Cardiology, 'Hippokration' Hosp, Athens, Greece; Antigoni Milliou, 'Hippokration' Hosp, Natl and Kapodistrian Univ of Athens Medical Sch, Athens, Greece; Assimakopoulos Margarita Niki, Nikolaos Barmparesos, Ioannis Giannarakis, Pinelopi Siamata, Natl and Kapodistrian Univ of Athens, Athens, Greece; Dimitrios Tousoulis, Ippokrateio Hosp, Athens, Greece

4:30 PM

Board # 3199

Chronic E-cigarette Users Demonstrate More Persistent Coronary Endothelial Dysfunction Than Chronic Combustible Cigarette Users

**Mohamad Rashid** , Katherine Davoren, Norma B. Moy, Fida Nafeh, Cedars-Sinai Medical Ctr, Los Angeles, CA; Robert Elashoff, UCLA Sch of Public Health, Los Angeles, CA; Chulkyu Kim, Andy Kim, Elizabeth Kim, Cedars-Sinai Medical Ctr, Los Angeles, CA; Michael D Nelson, UT Arlington, Mansfield, TX; Susan Cheng, Florian Rader, Cedars-Sinai Medical Ctr, Los Angeles, CA

4:30 PM

Board # 3200

Computed Tomography Attenuation of Pericardial but Not Intrathoracic Fat is a Novel Predictor of Long-term Cardiovascular Events Independent of Fat Volume

**Aiko Sakamoto** , Masae Uehara, Jiro Ando, Issei Komuro, Univ of Tokyo Graduate Sch of Med, Tokyo, Japan

4:30 PM

Board # 3201

Comparison of 8 Biomarkers to Predict Coronary Plaque Burden in Patients With and Without Chronic Kidney Disease: From the EXCEED-J Study

**Hiromichi Wada** , Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan; Tsuyoshi Shinozaki, Natl Hosp Organization Sendai Medical Ctr, Sendai, Japan; Masahiro Suzuki, Natl Hosp Organization Saitama Hosp, Suwa, Japan; Satoru Sakagami, Natl Hosp Organization Kanazawa Medical Ctr, Kanazawa, Japan; Yoichi Ajiro, Natl Hosp Organization Yokohama Medical Ctr, Yokohama, Japan; Junichi Funada, Natl Hosp Organization Ehime Medical Ctr, Toon, Japan; Morihiro Matsuda, Natl Hosp Organization Kure Medical Ctr and Chugoku Cancer Ctr, Kure, Japan; Masatoshi Shimizu, Natl Hosp Organization Kobe Medical Ctr, Kobe, Japan; Takashi Takenaka, Natl Hosp Organization Hokkaido Medical Ctr, Sapporo, Japan; Yukiko Morita, Natl Hosp Organization Sagamihara Natl Hosp, Sagamihara, Japan; Kazuya Yonezawa, Natl Hosp Organization Hakodate Natl Hosp, Hakodate, Japan; Hiromi Matsubara, Natl Hosp Organization Okayama Medical Ctr, Okayama, Japan; Yujiro Ono, Natl Hosp Organization Higashihiroshima Medical Ctr, Higashihiroshima, Japan; Toshihiro Nakamura, Natl Hosp Organization Kyushu Medical Ctr, Fukuoka, Japan; Kazuteru Fujimoto, Natl Hosp Organization Kumamoto Medical Ctr, Kumamoto, Japan; Kazuro Yoshida, Natl Hosp Organization Nagasaki Kawatana Medical Ctr, Higashisonogi-gun, Japan; Toru Kato, Natl Hosp Organization Tochigi Medical Ctr, Utsunomiya, Japan; Takashi Unoki, Daisuke Takagi, Saiseikai Kumamoto Hosp, Kumamoto, Japan; Moritake Iguchi, Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan; Kazuhiko Kotani, Jichi Medical Univ, Shimotsuke, Japan; Noriko Satoh-Asahara, Mitsuru Abe, Masaharu Akao, Koji Hasegawa, Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan

# Abstract Poster Session

## PH.APS.07 - Metabolic Derangements in Pulmonary Hypertension

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2273

Drpitor1a, a Novel Dynamin-related Protein 1 Inhibitor Prevents Right Ventricular Ischemia-reperfusion Injury

**Danchen Wu** , Asish Das Gupta, Kuang-Hueih Chen, Monica Neuber-Hess, Jignesh Patel, Timothy Hurst, Jeffrey D Mewburn, Patricia DA Lima, Ashley Martin, Michael Wells, Queen's Univ, Kingston, ON, Canada; Victor Snieckus, Queen's Univ, Kingston, ON, Canada; Stephen L Archer, Queen's Univ, Kingston, ON, Canada

4:30 PM

Board # 2274

The Sweet Side of Right Ventricular Dysfunction: Protein O-GlcNACylation is Associated With Metabolic Derangements and Impaired Right Ventricular Function

Lauren Rose, Univ of Minnesota, Minneapolis, MN; Lian Tian, Danchen Wu, Francois Potus, Monica Neuber-Hess, Queen's Univ, Kingston, ON, Canada; Thenappan Thenappan, Univ of Minnesota, Minneapolis, MN; Stephen L Archer, Queen's Univ, Kingston, ON, Canada; **Kurt W Prins** , Univ of Minnesota, Minneapolis, MN

4:30 PM

Board # 2276

SGLT2 Inhibitor Improved Exercise-induced Pulmonary Hypertension (EIPH) in Heart Failure With Preserved Ejection Fraction

**Taijyu Satoh** , Longfei Wang, Pittsburgh Univ, Pittsburgh, PA; Charles F McTiernan, Univ Pittsburgh, Pittsburgh, PA; Andrea Levine, Univ of Pittsburgh, Pittsburgh, PA; Jeff Baust, Pittsburgh Univ, Pittsburgh, PA; Yen Chun Lai, Indiana Univ, Indianapolis, IN; Mark T Gladwin, Univ Pittsburgh, Pittsburgh, PA

4:30 PM

Board # 2277

ATP13A3 **Loss of Function Disrupts Polyamine Homeostasis in Pulmonary Arterial Endothelial Cells**

**Bin Liu** , Ekaterina Legchenko, James A. West, Univ of Cambridge, Cambridge, United Kingdom; Norin Hamouda, Peter Vangheluwe, KU Leuven, Leuven, Belgium; Paul D. Upton, Nicholas A. Morrell, Univ of Cambridge, Cambridge, United Kingdom

4:30 PM

Board # 2278

Angiotensin II Receptor Blocker And Neprilysin Inhibitor Sacubitril/valsartan Attenuates Experimental Pulmonary Hypertension

Richard T. Clements, Providence VA Med Ctr/ Brown Univ, Providence, RI; Alexander Vang, Providence VA Med. Ctr., Providence, RI; Nouaying R. Kue, Thomas Mancini, Providence VA Med Ctr, Providence, RI; Alan R Morrison, Providence VA Med Ctr/ Brown Univ, Providence, RI; Danielle J McCullough, Edward Via Coll of Osteopathic Med-Auburn Campus, Auburn, AL; Krishna Mallem, **Gaurav Choudhary** , Providence VA Med Ctr/ Brown Univ, Providence, RI

4:30 PM

Board # 2279

A Direct Junctophilin-2 and Mitofusin-2 Interaction Links T-Tubule Remodeling to Metabolic Dysfunction in Right Ventricle Pressure Overload

**Sasha Z Prisco** , Univ of Minnesota, Minneapolis, MN; Lian Tian, Danchen Wu, Francois Potus, Ruaa Al-Qazazi, Monica Neuber-Hess, Stephen L Archer, Queen's Univ, Kingston, ON, Canada; Kurt W Prins, Univ of Minnesota, Minneapolis, MN

4:30 PM

Board # 2280

Neurohormonal Modulator Use And Mortality In Pulmonary Hypertension: Insights From The National Veterans Affairs Clinical Assessment Reporting And Tracking (cart) Program

**Tim Lahm** , Indiana Univ, Indianapolis, IN; Edward Hess, VA Eastern Colorado Health Care System, Denver, CO; Anna Baron, Univ of Colorado, Aurora, CO; Thomas M Maddox, Washington Univ, St Louis, MO; Meg E Plomondon, VA Eastern Colorado Health Car, Denver, CO; Gaurav Choudhary, Providence Vamc, Brown Univ, Providence, RI; Bradley Maron, Providence Vamc, Brown Univ, Providence, RI, Boston, MA; Roham Zamanian, Stanford Univ, Stanford, CA; Peter Leary, Univ of Washington, Seattle, WA

4:30 PM

Board # 2281

The Role of Interleukin-6 and the Microtubule-Junctophilin-2 Pathway in Right Ventricular Dysfunction in Pulmonary Arterial Hypertension

**Sasha Z Prisco** , Lauren Rose, Univ of Minnesota, Minneapolis, MN; Lian Tian, Danchen Wu, Francois Potus, Ruaa Al-Qazazi, Monica Neuber-Hess, Queen's Univ, Kingston, ON, Canada; Thenappan Thenappan, Univ of Minnesota, Minneapolis, MN; Stephen L Archer, Queen's Univ, Kingston, ON, Canada; Kurt W Prins, Univ of Minnesota, Minneapolis, MN

4:30 PM

Board # 2282

**Translationally Controlled Tumour Protein (** Tpt1 **) is a Novel Therapeutic Target for Lymphangioleiomyomatosis**

**Mirabelle Sh Ho** , Miriel Ho, Duncan J Stewart, Ottawa Hosp Res Inst, Ottawa, ON, Canada

# Abstract Poster Session

## AT.APS.06 - Metabolism and Vascular Disease

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 1076

**Advanced Glycation End Products Impair K** v **1-Mediated Coronary Arteries Vasodilation by Suppressing PPAR-gamma in Zucker Diabetic Fatty Rats**

**Bing Hua** , Qingbo Liu, Weiping Li, Hongwei Li, Beijing Friendship Hosp, Capital Medical Univ, Beijing, China

4:30 PM

Board # 1077

Vildagliptin, a DPP-4 Inhibitor, Attenuates Endothelial Dysfunction and Atherogenesis Independent of Its Glucose Lowering Effect in Apolipoprotein E-deficient Mice

**Aini Kunduziayi** , Daiju Fukuda, Tokushima Univ, Tokushima, Japan; Shusuke Yagi, Univ of Rochester, Tokushima, Japan; Kenya Kusunose, Yamada Hirotsugu, Takeshi Soeki, Masataka Sata, Tokushima Univ, Tokushima, Japan

4:30 PM

Board # 1080

Lipid Transfer to High Density Lipoproteins is Impaired and Cholesteryl Ester Transfer Protein Plasma Concentration is Diminished in Patients With Peripheral Arterial Disease

**Natalia M. Lopes** , Flávio R. c. m. Ribeiro, Insto do Coracao HCFMUSP Univ de Sao Paulo, São Paulo, Brazil; Carolina Heitmann Mares Azevedo, Univ of Para, Belem, Brazil; Thauany M. Tavoni, Insto do Coracao HCFMUSP Univ de Sao Paulo, São Paulo, Brazil; Erica S. Sarges, Insto de Ciencia da Saude, Univ Federal do Para, Belem, Brazil; Fatima R. Freitas, Camila Albuquerque, Roberto Kalil, Insto do Coracao HCFMUSP Univ de Sao Paulo, Sao Paulo, Brazil; Raul C. Maranhao, Insto do Coracao HCFMUSP Univ de Sao Paulo, São Paulo, Brazil

4:30 PM

Board # 1081

Risk of Mortality Associated With Serum Low-Density Lipoprotein Cholesterol Across Albuminuria Stages

Jui-Ting Hsiung, UC Irvine, Orange, CA; Melissa Soohoo, VA Long Beach, Long Beach, CA; Christina Park, UC Irvine, Orange, CA; Maria Marroquin, VA Long Beach, Long Beach, CA; Hamid Moradi, Long Beach VA Health Care System, Long Beach, CA; Csaba Kovesdy, Univ of Tennessee Health Science Ctr, Memphis, TN; Kamyar Kalantar-Zadeh, Univ of California Irvine, Orange, CA; **Elani Streja** , Univ of California, Irvine, Orange, CA

4:30 PM

Board # 1082

Serum Apolipoprotein B48 Concentration is Increased After Oral Glucose Intake and High in Patients With Impaired Glucose Tolerance

**Daisaku Masuda** , Hiroyuki Hanada, Shizuya Yamashita, Rinku General Medical Ctr, Izumisano, Osaka, Japan

4:30 PM

Board # 1083

Endothelial Cells From Patients With Pulmonary Hypertension Have Increased Glycolytic Flux Yet Decreased Endothelial Nitric Oxide Synthase Glycosylation

Sarah Basehore, Drexel Univ, Philadelphia, PA; **Alisa M Clyne** , Univ of Maryland, College Park, MD

4:30 PM

Board # 1084

LonP1 Reprograms Mitochondrial Metabolism in the Heart During I/R Injury

**Sundararajan Venkatesh** , Min Li, Rutgers-New Jersey Medical Sch, Newark, NJ; Mingming Tong, Rutgers-NJMS, Newark, NJ; Tong Liu, Hong Li, Rutgers-New Jersey Medical Sch, Newark, NJ; Peiyong Zhai, Junichi Sadoshima, Rutgers New Jersey Medical Sch, Newark, NJ; Carolyn K Suzuki, Rutgers- New Jersey Medical Sch, Newark, NJ

4:30 PM

Board # 1085

Sulfotransferase 2B1b Inhibits Reverse Cholesterol Transport and Promotes Cholesterol Accumulation and Inflammation in Lymphocytes From Acute Myocardial Infarction Patients With Low Low-Density Lipoprotein Cholesterol Levels

**Yanan Zhang** , Zhongzhou Guo, Tongwei Wu, Jiping Lang, Qiuyue Dai, Zhigang Guo, Nanfang Hosp, Southern Medical Univ, Guangzhou, China

# Abstract Poster Session

## HT.APS.01 - Mobile Health and Remote Monitoring

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Poster Professor

Adam P Bress, Salt Lake City, UT

4:30 PM

Board # 3133

Screening for Atrial Fibrillation in Native Americans Using Smartphone-Based ECG

**Khaled Elkholey** , Univ of Oklahoma, Oklahoma City, OK; Marty M. Lofgren, Absentee Shawnee Tribe Little Axe Health Ctr, Norman, OK; Karrie Q. Meeks, Zain Ul Abideen Asad, Univ of Oklahoma, Oklahoma City, OK; Ben Freedman, Heart Res Inst Sydney Uni, Sydney, Australia; Stavros Stavrakis, Univ of Oklahoma, Oklahoma City, OK

4:30 PM

Board # 3134

Assessment of Atrial Fibrillation Burden by Smartwatch Photoplethysmography

**Anthony Z Faranesh** , Alexandros Pantelopoulos, Andreea Milescu, Conor Heneghan, Fitbit, San Francisco, CA

4:30 PM

Board # 3135

Provider Perspectives on Smartwatch Monitoring for Atrial Fibrillation

**Eric Y Ding** , Emily Dickson, Daniella Albuquerque, Univ of Massachusetts Medical Sch, Worcester, MA; Jane S Saczynski, Northeastern Univ, Boston, MA; Ki Chon, Univ of Connecticut, Storrs, CT; David D McManus, Univ of Massachusetts Medical Sch, Worcester, MA

4:30 PM

Board # 3136

Beyond Apple 4 Watch and Af - Is Artificial Intelligence Ready to Take on ST Elevation Mi Diagnosis?

**Sameer Mehta** , Sebastian Niklitschek, Francisco Fernandez, Carlos Villagran, Felipe Vera, Mariana Ceschim, Gladys Pinto, Rodrigo Jacobucci, Lorena Pisana, Samantha Quintero, Genesis Del Nogal, Maritza Luna, Lilly Prieto, Benjamin Wood, Akhil Vaid, Lumen Fndn, Miami, FL

4:30 PM

Board # 3137

Feasibility of, and Adherence to, a Novel, Home-based Cardiac Tele-rehabilitation Program for Heart Attack Survivors: The MI-PACE Study

**Emily Ensom** , Daniella Albuquerque, Nathaniel Erskine, Univ of Massachusetts Medical Sch, Worcester, MA; Amy Peterson, Marlborough Hosp, Marlborough, MA; Emily Dickson, Eric Y Ding, Jaclyn Piche, Ziyue Wang, Jorge Escobar, Alvaro A Alonso, Raghavendra Makam, Naomi Botkin, Univ of Massachusetts Medical Sch, Worcester, MA; Wim Stut, Philips Res Europe, AE Eindhoven, Netherlands; David D McManus, Univ of Massachusetts Medical Sch, Worcester, MA

4:30 PM

Board # 3139

Enhancing Mobile Health to Achieve Both Hypertension and Diabetes Goals

Mansur Shomali, Vinayak Shenoy, Welldoc, Inc., Columbia, MD; Richard J Katz, George Washington Univ Med Ctr, Washington, DC; **Malinda Peeples** , Welldoc, Inc., Columbia, MD

4:30 PM

Board # 3140

More Frequent Remote Home Monitoring Decreases Blood Pressure in an Unselected Population of People With Diabetes

Karen Xu, **Roberta James** , Wei Lu, Anoop Sangha, Livongo Health, Mountain View, CA; Bimal R Shah, Livongo Health, DCRI, Mountain View, CA

4:30 PM

Board # 3141

Prevalence of Mobile Health Access and Use Among Individuals With or at Risk for Cardiovascular Disease: 2018 Health Information National Trends Survey (HINTS)

**Rongzi Shan** , Jie Ding, Johns Hopkins Univ Sch of Med, Baltimore, MD; Timothy B Plante, Univ of Vermont, Burlington, VT; Seth S Martin, Johns Hopkins Hosp, Baltimore, MD

# Abstract Poster Session

## HY.APS.05 - Novel Concepts in Hypertension Research

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2185

The Response of Resistance Vessels to High Intraluminal Pressure in Blacks and Whites

**Ahmad Sabbahi** , Assem Ellythy, Chueh-Lung Hwang, Shane A Phillips, Univ of Illinois at Chicago, Chicago, IL

4:30 PM

Board # 2186

Pro-SAAS Peptides, GPR83 Function and Salt Resistance

**Xiaoxu Zheng** , Megha Kumar, George Washington Univ, Washington, DC; Prasad Konkalmatt, The George Washington Univ, Washington, DC; Laureano D Asico, Pedro A Jose, Ines Armando, George Washington Univ, Washington, DC

4:30 PM

Board # 2187

Aldosterone Inhibition by a Novel GC-A Activator MANP Through GC-A/cGMP/PDE2 Pathway in Human Adrenal Cells

**Yang Chen** , Seethalakshmi R Iyer, Hon-chi Lee, Jeson Sangaralingham, John C Burnett, Mayo Clinic, Rochester, MN

4:30 PM

Board # 2188

Reduction in Anti-Hypertensive Medication After Epicardial Left Atrial Appendage Exclusion - Emerging Evidence of Pleiotropic Adjunctive Benefit?

**Dhanunjaya Lakkireddy** , Kansas City Heart Rhythm Inst, Overland Park, KS; Yashasvi Awasthi, Atricure Inc, Woodbury, MN; Michael Ferguson, Atricure, Overland Park, KS; Xian Shen, Erin Sullivan, Atricure, MInnetonka, MN; Krzystof Bartus, Jagiellonian Univ Medical Coll, John Paul II Hosp, Krakow, Poland; Mohit K Turagam, Univ of Missouri, Columbia, MO; Sharan Sharma, Rakesh Gopinathannair, Kansas City Heart Rhythm Inst, Overland Park, KS; Justin VanMeetren, HCA Health Midwest, Overland Park, KS; Ahmed Romeya, HCA Healthcare, Overland Park, KS; James L Cox, Georgetown Univ, Washington, DC

4:30 PM

Board # 2189

Angiotensin-(1-12) Modulation of Cardiomyocyte Functional Performance in Wistar-Kyoto and Spontaneously Hypertensive Rats

**Zhe Chen** , Yixi Liu, Heng-Jie Cheng, Jessica VonCannon, Sarfaraz Ahmad, Jasmina Varagic, Carlos M Ferrario, Che Ping Cheng, Wake Forest Sch of Med, Winston-Salem, NC

4:30 PM

Board # 2190

A Common Mechanism of Autoinflammation in Systemic Lupus Erythematosus and Essential Hypertension

**David M Patrick** , Vanderbilt Univ Medical Ctr, Nashville, TN; Nestor de la Visitacion, Univ of Granada, Granada, Spain; Annet Kirabo, Vanderbilt Univ Medical Cente, Nashville, TN; Mingfang Ao, Vanderbilt Univ Medical Ctr, Nashville, TN; Markus Kalkum, City of Hope, Duarte, CA; Roeth Daniel, Vanderbilt Univ Medical Ctr, Duarte, CA; David G Harrison, Vanderbilt, Nashville, TN

4:30 PM

Board # 2191

Dopamine D2 Receptor Specific Deletion in the Renal Proximal Tubules Increases Blood Pressure in Males but Not Female Mice

**Megha Kumar** , Prasad Konkalmatt, Laureano D Asico, Jessica Hunt, Patricia Latham, Pedro A Jose, Ines Armando, George Washington Univ, Washington, DC

4:30 PM

Board # 2192

Inactivation of Serca2 Cysteine 674 Increases Blood Pressure by Induction of Endoplasmic Reticulum Stress and Soluble Epoxide Hydrolase

**Gang Liu** , Chongqing Univ, Chongqing, China; Fuhua Wu, Xiaoli Jiang, Weimin Yu, Xiaoyong Tong*

4:30 PM

Board # 2193

Del-1 Inhibits Inflammation and Protects From Cardiovascular Damage During Hypertension

**Irakli Kopaliani** , Theresa Failer, Ales Neuwirth, Ioannis Kourtzelis, Pallavi Subramanian, Dresden Univ of Technology, Dresden, Germany; George Hajishengallis, Univ of Pennsylvania, Philadelphia, PA; Triantafyllos Chavakis, Andreas Deussen, Dresden Univ of Technology, Dresden, Germany

4:30 PM

Board # 2194

Paraoxonase 3 is Renoprotective in a Dahl Salt-Sensitive Rat Model of Chronic Kidney Disease

**Chrysan J Mohammed** , Fatimah K Khalaf, Prabhatchandra Dube, Dhanushya Battepati, Iman Tassavvor, Andrew L Kleinhenz, Amira Gohara, Steven T. Haller, David J Kennedy, Univ of Toledo Health Science Campus, Toledo, OH

4:30 PM

Poster Professor

Qiangrong Liang, Old Westbury, NY

4:30 PM

Board # 2195

Pharmacologically Lowering Blood Pressure May Not Improve Conduit Artery Endothelial Function in Hypertensive Adults

**Corinna Serviente** , Gabrielle Dillon, Pennsylvania State Univ, University Park, PA; Jody L Greaney, Univ of Texas at Arlington & Pennsylvania State Univ, Arlington, TX; Anna E Stanhewicz, Lacy M Alexander, Pennsylvania State Univ, University Park, PA

# Abstract Poster Session

## LF.APS.03 - Nutrition, Bariatric Surgery and Cardiometabolic Health

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 3183

Potatoes and Cardiometabolic Health: A Randomized, Cross-over Study

**Emily A Johnston** , The Pennsylvania State Univ, University Park, PA; Kristina S Petersen, Penny M Kris-Etherton, Pennsylvania State Univ, University Park, PA

4:30 PM

Board # 3184

Impact of Geriatric Nutritional Risk Index on Heart Failure Re-Hospitalization in Patients With Heart Failure With Preserved Ejection Fraction Compared With Hfmref and Hfref

**Shintaro Mori** , Kokura Memorial Hosp, Kitakyushu, Japan; Takashi Morinaga, Kokura Memorial Hosp, Kitakyusyu, Japan; Akihiro Isotani, Kokura Memorial Hosp, Kitakyushu, Japan

4:30 PM

Board # 3185

Intermittent Fasting Lifestyle and Human Longevity in Cardiac Catheterization Populations

**Benjamin D Horne** , Intermountain Heart Inst, Univ of Utah, Salt Lake City, UT; Ciera Bartholomew, Brigham Young Univ, Provo, UT; Jeffrey Lance Anderson, Heidi T May, Kirk Ute Knowlton, Intermountain Medical Ctr, Salt Lake City, UT; Tami L Bair, Intermountain Medical Ctr, Salt Lake Cty, UT; Viet T LE, Intermountain Medical Ctr, Salt Lake City, UT; Bruce W Bailey, Brigham Young Univ, Provo, UT; Joseph Brent Muhlestein, Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT

4:30 PM

Board # 3186

Effects of Carbohydrate Quality and Amount on Plasma Lactate: Results From the Omnicarb Trial

**Jiun-Ruey Hu** , Vanderbilt Univ Medical Ctr, Nashville, TN; Yingfei Wu, Johns Hopkins Univ Sch of Public Health, Baltimore, MD; Frank M Sacks, Harvard Chan Sch of Public Health, Boston, MA; Lawrence J Appel, Edgar R Miller, J Hunter Young, Johns Hopkins Univ Sch of Public Health, Baltimore, MD; Stephen P Juraschek, BIDMC-Harvard Medical Sch, Auburndale, MA

4:30 PM

Board # 3187

Patients With Prior Myocardial Infarction or Prior Percutaneous Coronary Intervention Have Increased Perioperative Mortality and Adverse Cardiac Events Following Bariatric Surgery

**Brandon Peterson** , Kalins Banerjee, Xiang Zhan, Andrew Foy, Penn State Hershey Medical Ctr, Hershey, PA

4:30 PM

Board # 3188

Qt Interval and Blood Pressure Changes With Energy Drinks Consumption in Healthy Subjects: A Meta-Analysis of Randomized Trials

Alexandre M Benjo, Ochsner Medical Ctr, Metairie, LA; Valentina Jaramillo, Univ CES, Medellin, Colombia; Francisco Nascimento, Lake Side Heart and Vascular, Lake Havasu City, AZ; Fadi Atassi, Cardiology and Fitness Med, Delray Beach, FL; Dhruv Mahtta, Univ of Florida, Gainesville, FL; Jonas M Benjo, na, Boca Raton, FL; David C Benjo, n/a, Boca Raton, FL; **Carlos L Alviar** , New York Univ, New York, NY

4:30 PM

Board # 3189

Dietary Habits and Hypertension in Women of Child-Bearing Age: Dash Concordance in NHANES 2001-2016

**Lara C Kovell** , Benjamin Maxner, Didem Ayturk, Tiffany A Moore Simas, Colleen M Harrington, David D McManus, Gerard P Aurigemma, Univ of Massachusetts Medical Sch, Worcester, MA; Stephen P Juraschek, BIDMC-Harvard Medical Sch, Boston, MA

4:30 PM

Board # 3190

Bariatric Surgery Improves Vascular Regenerative Capacity by Reducing Inflammatory Cell Burden and Raising Pro-Vascular Progenitor Cell Content

**Justin Z Trac** , St Michael's Hosp, Toronto, ON, Canada; Stephen A Glazer, Humber River Regional Hosp, Toronto, ON, Canada; Daniella Terenzi, Hwee Teoh, Mohammed Al-Omran, Adrian Quan, Ori Rotstein, St Michael's Hosp, Toronto, ON, Canada; David Andrew Hess, Robarts Res Inst, London, ON, Canada; Subodh Verma, St Michael's Hosp, Toronto, ON, Canada

4:30 PM

Board # 3191

Dried Fruit and Cardiometabolic Health: A Randomized Crossover Trial

**Valerie K Sullivan** , Kristina S Petersen, Penny M Kris-Etherton, The Pennsylvania State Univ, University Park, PA

4:30 PM

Board # 3192

Length of Food Chain is Crucial in Determining the Impact of Mediterranean Diet on Metabolic Syndrome and Cardiovascular Risk

**Gaetano Santulli** , Albert Einstein Coll of Med - Montefiore Univ Hosp - ITME, New York, NY; Valeria Pascale, Salerno Univ, Baronissi (SA), Italy; Rosa Finelli, Salerno Univ, Baronissi, Italy; Valeria Visco, Salerno Univ, Salerno, Italy; Enrico Coscioni, "San Giovanni di Dio e Ruggi d'Aragona" Univ Hosp, Salerno, Italy; Rocco Giannotti, Salerno Univ, Baronissi, Italy; Angelo Massari, "San Giovanni di Dio e Ruggi d'Aragona" Univ Hosp, Salerno, Italy; Michele Ciccarelli, Salerno Univ, Baronissi, Italy; Guido Iaccarino, Federico II Univ, Naples, Italy

# Abstract Poster Session

## CH.APS.06 - Pediatric Sudden Cardiac Death

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 4091

CPR in Chicago Public Schools; A Survey for Implementation of Sudden Cardiac Arrest Education in Schools

**Alyssa Vermeulen** , Rush Univ Medical Ctr, Chicago, IL; Marina Del Rios, Univ of Illinois at Chicago, Chicago, IL; Teri Campbell, Univ of Illinois Chicago, Chicago, IL; Hoang Nguyen, Rush Univ Medical Coll, Chicago, IL

4:30 PM

Board # 4093

Implantable-Cardioverter Defibrillator Use in Adult Congenital Heart Disease Patients

**Zoe Schefter** , Amy zlotnik Walsh, Boston Children's Hosp, Boston, MA; Anne Marie Valente, Boston Childrens Hosp, Boston, MA; Mark E Alexander, Children s Hosp, Boston, MA; Elizabeth S Dewitt, Vassilios J Bezzerides, Boston Childrens Hosp, Boston, MA; John K Triedman, Childrens Hosp Boston, Boston, MA; Douglas Y Mah, Boston Children's Hosp, Boston, MA

4:30 PM

Board # 4094

Sudden Cardiac Death-associated Ryanodine Receptor 2 Gene Variants Localize to Structural Regions of Ion Gating and Conductance Compared to Population and Incidentally-identified Variants

**Perathu Kannu Manivannan** , Duke Univ Sch of Med, Durham, NC; Deshun Gong, Ximin Chi, Tsinghua Univ, Beijing, China; Hugh D Allen, Jeffrey Kim, Texas Childrens Hosp, Houston, TX; Andrew P Landstrom, Duke Univ Sch of Med, Durham, NC

4:30 PM

Board # 4095

Initial Energy Dose and Survival to Hospital Discharge for Pediatric In-hospital Cardiac Arrest Due to Pulseless Ventricular Arrhythmia

**Derek B Hoyme** , Univ of Wisconsin Madison, Madison, WI; Yunshu Zhou, Saket Girotra, Univ of Iowa, Iowa City, IA; Marc Berg, Stanford Sch of Med, Menlo Park, CA; Robert A Berg, Childrens Hosp of Philadelphia, Philadelphia, PA; Sarah E Haskell, Univ of Iowa, Iowa City, IA; Mary Fran Hazinski, Vanderbilt Univ, Nashville, TN; Javier J Lasa, Texas Children's Hosp, Houston, TX; Peter Andrew Meaney, Stanford Sch of Med, Menlo Park, CA; Vinay M Nadkarni, Childrens Hosp of Philadelphia, Philadelphia, PA; Ricardo A Samson, Childrens Heart Ctr Nevada, Las Vegas, NV; Dianne L Atkins, Univ of Iowa, Iowa City, IA

4:30 PM

Board # 4096

The Association Between Sudden Unexpected Death in Infancy and Neighborhood-Level Disadvantages: A Multi-Dimension Evaluation in the City of Chicago

**Hai Nguyen** , Univ of Illinois Chicago, Chicago, IL; Marina Del Rios, Univ of Illinois at Chicago, Chicago, IL; Oksana Pugach, Univ of Illinois Chicago, Chicago, IL; Hoang H Nguyen, Rush Univ Medical Coll, Chicago, IL

4:30 PM

Board # 4097

Physician Involvement in Prehospital Advanced Life Support and Neurologically Favorable Survival After Pediatric Out-of-hospital Cardiac Arrest: Results From a Japanese Registry-Based Study

**Tatsuma Fukuda** , Univ of the Ryukyus, Okinawa, Japan; Naoko Ohashi-Fukuda, Naha City Hosp, Okinawa, Japan; Hiroshi Sekiguchi, Univ of the Ryukyus, Okinawa, Japan; Yutaka Kondo, Juntendo Univ Urayasu Hosp, Chiba, Japan; Ichiro Kukita, Univ of the Ryukyus, Okinawa, Japan

4:30 PM

Board # 4098

Myocardial Ischemia is Common in Anomalous Aortic Origin of a Coronary Artery With Intraseptal Course

**Tam Doan** , Texas Children's Hosp | Baylor Coll of Med, Houston, TX; Rodrigo Zea-Vera, Baylor Coll of Med, Houston, TX; Hitesh Agrawal, Texas Children's Hosp, Houston, TX; Carlos M. Mery, UT Austin Dell Medical Sch, Austin, TX; Prakash Masand, Texas Children's Hosp, Houston, TX; Dana Reaves-O'Neal, Texas Children's Hosp | Baylor Coll of Med, Houston, TX; Cory Noel, Texas Children's Hosp, Houston, TX; Athar M Qureshi, Kristen Sexson Tejtel, Texas Children's Hosp | Baylor Coll of Med, Houston, TX; Charles D Fraser, Dell Medical Sch - UT Austin, Austin, TX; Silvana M Molossi, BCM Texas Children's Hosp, Houston, TX

4:30 PM

Board # 4099

Risk of Late Sudden Cardiac Death After Surgery for Congenital Heart Disease

**Robert Whitehill** , Courtney McCracken, Emory Univ, Atlanta, GA; Jeffrey M Vinocur, Univ of Rochester Medical Ctr (URMC), Rochester, NY; Matthew Oster, Children s Healthcare of Atlanta, Atlanta, GA; Lazaros Kochilas, Emory Univ, Atlanta, GA

4:30 PM

Board # 4100

Presentation and Surgical Outcomes of Patients With Anomalous Left Coronary Artery From the Pulmonary Artery Diagnosed After One Year of Age: A Multicenter Study

**David M Kwiatkowski** , Stanford Univ Sch of Med, Palo Alto, CA; Katherine Cashen, Children's Hosp of Michigan, Detroit, MI; Saurabh Chiwane, Cardinal Glennon Children's Hosp, St Louis Univ, St Louis, MO; Saul Flores, Texas Children's Hosp, Houston, TX; Ilias Iliopoulos, Cincinnati Children's Hosp, Cincinnati, OH; Jennifer Smerling, Columbia Univ, New York, NY; Christopher Mastropietro, Indiana Univ Sch of Med, Indianapolis, IN; Karl Migally, Northwestern Univ Sch of Med, Chicago, IL; Monique Rochelle Radman, Seattle Childrens Hosp, Seattle, WA; Christine Marie Riley, Children's Natl Medical Ctr, Washington, DC; Peter Sassalos, C.S. Mott Children's Hosp, Ann Arbor, MI; John M Costello, Medical Univ. of South Carolina, Charleston, SC

4:30 PM

Poster Professor

Jeffrey P. Moak, Washington, DC

# Abstract Poster Session

## SA.APS.04 - Predictors of Outcomes Around Cardiac Surgery

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 4284

Coexistent Arterial Hypertension In Patients With Severe Isolated Calcific Aortic Stenosis Is Associated With Worse Long-term Survival After Surgical Aortic Valve Replacement

**Yavor Dimitrov Peychev** , Univ Hosp, Varna, Bulgaria

4:30 PM

Board # 4285

Accumulation of Advanced Glycation End Products Results in Inflammation-Mediated Structural Degeneration of Bioprosthetic Heart Valves

**Andrey Zakharchenko** , Children's Hosp of Philadelphia, Philadelphia, PA; Samuel Keeney, Children's Hosp of Philadelphia, Philadelphia, PA; Stanley Joseph Stachelek, Childrens Hosp of Philadelphia, Philadelphia, PA; Giovanni Ferrari, Columbia Univ, New York, NY; Hajime Takano, Children's Hosp of Philadelphia, Philadelphia, PA; Robert Levy, Children's Hosp of Philadelphia, Philadelphia, PA

4:30 PM

Board # 4286

Frailty in Older Adults Undergoing Mitral Valve Procedures, Reversible or Not?

**Joshua Schwartz** , McGill Univ, Montreal, QC, Canada; Emmanuel Moss, Jonathan Afilalo, Jewish General Hosp, Montreal, QC, Canada

4:30 PM

Board # 4287

A Systematic Review and Meta-Analysis of Transeptal vs Left Atrial Approach for Mitral Valve Surgery

**Amer Harky** , Arish Noshirwani, Dimitrios Pousios, Andrew D Muir, Liverpool Heart and Chest Hosp, Liverpool, United Kingdom

4:30 PM

Board # 4288

Transcatheter versus Surgical Aortic Valve Replacement in Patients With Prior Cardiac Surgery: A Systematic Review and Meta-Analysis

**Noman Lateef** , Muhammad Junaid Ahsan, Creighton Univ, Omaha, NE; Saad Ullah Malik, Rawalpindi Medical Coll, Rawalpindi, Pakistan; Abdul Mannan Minhas, Orange Park Medical Ctr, Orange Park, FL; Abdul Haseeb, Wright Graduate Medical Ctr, Scranton, PA; Mohsin Mansoor Mirza, Creighton Univ, Omaha, NE; Rami Doukky, John H. Stroger, Jr. Hosp of Cook County, Chicago, IL; Nancy Koster, Creighton Univ, Omaha, NE

4:30 PM

Board # 4289

In-Hospital Outcomes of Transcatheter versus Surgical Aortic Valve Replacement in Previously Placed Permanent Pacemaker Patients

**Mohinder Reddy Vindhyal** , KUSM-Wichita, Wichita, KS; Paul Muutu Ndunda, Univ of Kansas Sch of Med-Wichita, Wichita, KS; Hayrettin Okut, KUSM-Wichita, Wichita, KS; Zaher Fanari, Univ of Kansas Wichita, Wichita, KS

4:30 PM

Board # 4290

Does Gender Impact Outcomes Following Mitral Valve Surgery? Comparison Between Sternotomy and Minimally Invasive Approaches

**Maciej Debski** , Amr Abdelrahman, Syed Qadri, Joseph Zacharias, Kenneth Wong, Lancashire Cardiac Ctr, Blackpool Teaching Hosp NHS Fndn Trust, Blackpool, United Kingdom

4:30 PM

Board # 4291

Short- and Long-term Outcomes After Surgical Aortic Valve Replacement in Patients With Classical Low-flow, Low-gradient Aortic Stenosis

**Vitor E e Rosa** , Henrique B Ribeiro, Univ of Sao Paulo Medical Sch, Sao Paulo, Brazil; Roney O Sampaio, Heart Institue, Sao Paulo, Brazil; Thamara Carvalho Morais, Dante Pazzanese, Aracju, Brazil; Marcela E e Rosa, Univ of Sao Paulo Medical Sch, Sao Paulo, Brazil; Antonio S De Santis, Insto Do Coratpo - Incor, Sao Paulo, Brazil; Joao Ricardo C Fernandes, Univ of Sao Paulo Medical Sch, Sao Paulo, Brazil; Guilherme S Spina, Insto do Cora??o ( InCor )-HC, S?o Paulo, Brazil; Marcelo L Vieira, Hosp Israelita Albert Einstein, Sao Paulo, Brazil; Pablo M A Pomerantzeff, Heart Inst Univ of SP, S?Paulo, Brazil; Carlos Eduardo Rochitte, Incor Univ of Sao Paulo, Sao Paulo, Brazil; Wilson Mathias Jr, Univ of Sao Paulo Medical Sch, Sao Paulo, Brazil; Flavio Tarasoutchi, InCor HCFMUSP, S?o Paulo, Brazil

4:30 PM

Board # 4292

Relationship Between Atrial Fibrillation and Sleep Apnea Syndrome in Patients Undergoing Surgicalmanagementof the Left Atrial Appendage

**Takaharu Shimizu** , Yoshihiro Suematsu, Kanan Kurahashi, Daisuke Arima, Satoshi Nishi, Akihiro Yoshimoto, Sei Morizumi, Tsukuba Memorial Hosp, Tsukuba-City, Ibaraki, Japan

# Abstract Poster Session

## HF.APS.07 - Prognostic Indicators for Valvular Heart Disease

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2114

New Cardiac Damage Staging Classification in Patients With Asymptomatic Primary Moderate or Severe Mitral Regurgitation

**Jeremy Bernard** , Quebec Heart and Lung Inst, Quebec, QC, Canada; Marlène Dupuis, Quebec Heart and Lung Inst, Quebec city, QC, Canada; Oumhani Toubal, Haïfa Mahjoub, O'Connor Kim, Jonathan Beaudoin, Mathieu Bernier, Quebec Heart and Lung Inst, Quebec, QC, Canada; Nancy Cote, CRIUCPQ, Quebec, QC, Canada; Marie Annick Clavel, Quebec Heart Inst, Quebec, QC, Canada; Philippe Pibarot, IUCPQ-UL, Quebec, QC, Canada

4:30 PM

Board # 2115

Predictors of Clinical Outcomes According to the Stages of Rheumatic Mitral Stenosis

Maria Do Carmo Pereira Nunes, UFMG, Belo Horizonte, Brazil; **Bruno R Nascimento** , Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Jacob P Dal-Bianco, Massachusetts General Hosp, Boston, MA; Timothy C Tan, Univ of Sydney, Sydney, Australia; Marta Eugenia Acici, Breno C Spolaor, Maria Cecília L Nassif, Lucas C Silva, Igor F Sales, Guilherme Rafael Sant anna Athayde, Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Lucas Lodi-Junqueira, Hosp Mater Dei Contorno, Belo Horizonte, Brazil; William Esteves, Hosp Vera Cruz, Belo Horizonte, Brazil; Judy Hung, Robert A Levine, Massachusetts General Hosp, Boston, MA

4:30 PM

Board # 2116

Predictors of In-hospital Mortality in Patients With Newly Diagnosed Non-bacterial Thrombotic Endocarditis: A Systemic Review

**Nithin Rao Venepally** , Mayo Clinic, Phoenix, AZ; Pradyumna Agasthi, Mayo Clinic, Scottsdale, AZ; Farouk Mookadam, Banveet K Khetarpal, Mayo Clinic, Phoenix, AZ; Panwen Wang, Mayo Clinic, Scottsdale, AZ; Sudheer Konduru, Ayman R Fath, Reza Arsanjani, Mayo Clinic, Phoenix, AZ

4:30 PM

Board # 2117

Dialysis Access as a Source of Infective Endocarditis in Dialysis Patients

**Hee D Jeon** , Kevin B Lo, Andrea Faggiano, Eduardo E Quintero, Byeori Lee, Asma Gulab, Ruchika Bhargav, Albert Einstein Medical Ctr, Philadelphia, PA; Jayanth Vatson, Sidney Kimmel Medical Coll, Philadelphia, PA; John Lozowski, Philadelphia Coll of Osteopathic Med, Philadelphia, PA; Evan Friend, Jeri C Albano, Albert Einstein Medical Ctr, Philadelphia, PA; Gregg S Pressman, Einstein Cardiology Assoc, Philadelphia, PA

4:30 PM

Board # 2118

Safety of Direct Oral Anti-Coagulation Agents in Patients With Bio-Prosthetic Valves

**Navid Berenji** , Omar Sheikh, UT Health San Antonio, San Antonio, TX; Gregory Kendall, Univ of Texas Health, San Antonio, TX; Mustafa Al-Qaysi, UT Health San Antonio, San Antonio, TX; Debanshu Roy, UT Health San Antonio, San Antonio; Ariel Vinas, UT Health San Antonio, San Antonio, TX; Edward Sako, UT Health San Antonio, San Antonio; Andrea Carpenter, Auroa Badin, Manoj M Panday, UT Health San Antonio, San Antonio, TX; Dhanunjaya Lakkireddy, Univ of Kansas Health System, Kansas City, KS; Jayasree Pillarisetti, UT health San Antonio, San Antonio, TX

4:30 PM

Board # 2119

Sudden Cardiac Death Due to Valvular Heart Disease

**Lauri Holmstroem** , Jarkko Piuhola, Juha Vähätalo, Anette Haukilahti, Tuomas Kentta, Lasse Pakanen, Juha Perkiomaki, Matti Niemela, Kari Kervinen, Univ of Oulu, Oulu, Finland; Heikki Huikuri, Oulu Univ Hosp, Los Angeles, CA; Juhani Junttila, Univ of Oulu, Oulu, Finland

4:30 PM

Board # 2120

Temporal Trends of Diagnosis and Complications of Bicuspid Aortic Valve: Insight From a Large Korean Registry

Chi Young Shim, **Shinjeong Song** , Ji Won Seo, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Geu-Ru Hong, Yonsei Univ, Seoul; Jong-Won Ha, Yonsei Univ Coll of Med, Seoul

4:30 PM

Board # 2121

Inflammatory Biomarkers as Predictors of Staphylococcus Aureus Infection and Mortality in Infective Endocarditis

**Alberto Aimo** , Univ Hosp of Pisa, Pisa, Italy; Carlo Tascini, Ospedale Cotugno, Naples, Italy; Chiara Arzilli, Univ Hosp of Pisa, Pisa, Italy; Francesco Sbrana, Fondazione Toscana Gabriele Monasterio, Pisa, Italy; Andrea Ripoli, FTGM, Pisa, Italy; Lorenzo Ghiadoni, Univ of Pisa, Pisa, Italy; Chiara Bertone, Univ Hosp of Pisa, Pisa, Italy; Claudio Passino, Fondazione Toscana Gabriele Monasterio, Pisa, Italy; Vittorio Attanasio, Ospedale Cotugno, Naples, Italy; Emanuela Sozio, Livorno Hosp, Livorno, Italy; Carlo Pallotto, Univ Hosp of Perugia, Perugia, Italy; Stefano Maffei, FTGM, Massa, Italy; Michele Emdin, Fondazione Toscana Gabriele Monasterio, Pisa, Italy

4:30 PM

Board # 2122

Determinants of the Improvement of Atrial Functional Mitral Regurgitation After Catheter Ablation for Atrial Fibrillation: Analysis of Three-Dimensional Multislice Computed Tomography and Transthoracic Echocardiography

**Yuta Tsujisaka** , Kitae Kim, Kaji Shuichirou, Yasuhiro Sasaki, Takeshi Kitai, Atsushi Kobori, Misun Pak, Toshiaki Toyota, Natsuhiko Ehara, Makoto Kinoshita, Yutaka Furukawa, Kobe City Medical Ctr General Hosp, Kobe, Japan

4:30 PM

Board # 2123

The Effect of Permanent Pacemaker Implantation Following Transcatheter Aortic Valve Replacement Upon Survival

George Oikonomou, Agia Paraskevi, Athens, Greece; Konstantinos Toutouzas, Athens Medical Sch, Athens; Maria Drakopoulou, First Dept of Cardiolgy, Athens, Greece; Stergios Soulaidopoulos, **Konstantinos Stathogiannis** , Maria Xanthopoulou, Pantelis Toskas, George Trantalis, Hippokration Hosp, Athens, Greece; George Latsios, NHS Greece, Athens; Dimitrios Tousoulis, Ippokrateio Hosp, Athens, Greece

4:30 PM

Poster Professor

Robert K Riemer, Stanford, CA

# Abstract Poster Session

## CM.APS.03 - Risk Pathways and Risk Reduction in Diabetes: Exploring Mechanisms

#### Zone 3, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 3023

Impairment in Cardiorespiratory Fitness in Subjects With Diabetes Mellitus Without Clinical Heart Failure

**Michel White** , Montreal Heart Inst, Montreal, QC, Canada; Joshua Abella, US Dept of Veteran Affairs, Palo Alto, CA; Jeffrey W Christle, Stanford Health Care, Fremont, CA; Ross Arena, Univ of Illinois, Chicago, IL; Leonard A Kaminsky, Ball State Univ, Muncie, IN; Anna Nozza, Montreal Health Innovations Coordination Ctr, Montreal, QC, Canada; Jonathan N Myers, VA Palo Alto Health Care System, Palo Alto, CA

4:30 PM

Board # 3024

Mitochondrial Fusion Promoter Effectively Alleviates Mitochondrial Dysfunction And Improves Cardiac Function In Diabetic Rats

**Mingge Ding** , Xi'an No.3 Hosp, Xian, China; Ke Zeng, Mingzhe Yu, Fourth Mlitary Medical Univ, Xian; Feng Fu, Fourth Military Medical Univ, Xian, China

4:30 PM

Board # 3025

Metabolite Markers of Incident Type 2 Diabetes and Cardiovascular Disease in the Jackson Heart Study

**Zsu-Zsu Chen** , Beth Israel Deaconess Medical Ctr, Boston, MA; Yan Gao, Univ of Mississippi Medical Ctr, Jackson, MS; Daniel E Cruz, Usman Tahir, BIDMC, Boston, MA; Bennet Peterson, Jeremy Robbins, Mark Benson, Beth Israel Deaconess Medical Ctr, Boston, MA; Debby Ngo, Beth Israel Deaconess, Boston, MA; Adolfo Correa, Beth Israel Deaconess Medical Cente, Jackson, MS; Clary Clish, Broad Inst of MIT and Harvard, Cambridge, MA; James Wilson, Robert E Gerszten, Beth Israel Deaconess Medical Ctr, Boston, MA

4:30 PM

Board # 3026

**Cardioprotection in Diabetic Cardiomyopathy via Upregulation of Atp-sensitive K** + **Channels**

Arkady Uryash, Mount Sinai Medical Ctr Res, Miami Beach, FL; **Jose Antonio Adams** , Jose R Lopez, Mount Sinai Medical Ctr, Miami Beach, FL

4:30 PM

Board # 3028

The Effect of Exenatide Once-Weekly on Carotid Atherosclerosis and Endothelial Function in Persons With Type 2 Diabetes: An 18-Month Randomized Placebo-Controlled Study

**Juraj Koska** , Raymond Migrino, Keith C Chan, Kelly Cooper-Cox, Peter D Reaven, Phoenix VA Health Care System, Phoenix, AZ

4:30 PM

Board # 3029

**Chronic Beta3-Adrenergic Receptor Antagonist Therapy Rescues Diabetic Cardiomyopathy Through Ca** 2+ **/Calmodulin-Dependent Protein Kinase II Inhibition**

**Heng-Jie Cheng** , Yixi Liu, Zhe Chen, Xiaowei Zhang, Dalane Kitzman, Donald A McClain, Che Ping Cheng, Wake Forest Sch of Med, Winston-Salem, NC

4:30 PM

Board # 3030

Disrupting Interleukin-12 Improves Vascular Endothelial Function In Type 2 Diabetes

Eman Radwan, Assiut Univ, Assiut, Egypt; Souad Belmadani, Easterm Virginia Medical Sch, Norfolk, VA; **Khalid Matrougui** , Eastern Virginia Medical Sch, Norfolk, VA

4:30 PM

Board # 3031

Canagliflozin, a SGLT2 Inhibitor Improves Skeletal Muscle Function in High-Fat Diet-Fed Obesity Mice

**Tomohiro Komatsu** , Satomi Abe, Shihoko Nakashima, Eri Soneda, Yasuki Higaki, Yoshinari Uehara, Fukuoka Univ, Fukuoka, Japan

4:30 PM

Board # 3032

Empagliflozin Restores Lowered Exercise Endurance Capacity via the Activation of Skeletal Muscle Fatty Acid Oxidation in Murine Heart Failure

**Hideo Nambu** , Hokkaido Social Work Association Obihiro Hosp, Obihiro, Japan; Shingo Takada, Hokusho Univ, Ebetsu, Japan; Satoshi Maekawa, Otaru-kyokai hospital, Otaru, Japan; Naoya Kakutani, Hokkaido Univ, Sapporo, Japan; Takaaki Furihata, Stanford Sch of Med, Stanford, CA; Akimichi Saito, Health Sciences Univ of Hokkaido, Sapporo, Japan; Arata Fukushima, Asabu Heart and Gastrointestinal Clinic, Sapporo, Japan; Takashi Yokota, Shintaro Kinugawa, Hokkaido Univ, Sapporo, Japan

# Abstract Poster Session

## CH.APS.10 - Simple or Not So Simple? Long Term Outcomes in Adult Patients with Septal Defects

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 4131

Resolution of Migraine With or Without Aura After Transcatheter Closure of Patent Foramen Ovale: Prospective Evaluation

**Teiji Akagi** , Okayama Univ Hosp, Okayama, Japan; Takashi Miki, Okayama Univ Hosp, Okayama-city, Japan; Yoichi Takaya, Natl Cardiovascular Ctr, Mino City, Japan; Koji Nakagawa, Cardiovascular Surgery, Okayama Univ, okayama, Japan; Rie Nakayama, Norihisa Toh, Okayama Univ Hosp, Okayama, Japan; Hiroshi Ito, Okayama Univ, Okayama, Japan

4:30 PM

Board # 4132

Left Ventricular Changes After Percutaneous Atrial Septal Defect Closure With High Left Ventricular Diastolic Pressure

**Takehiko Yokoyama** , Japanese Red Cross Nagoya Daini Hosp, Nagoya, Japan; Kenji Furusawa, Nagoya Univ Hosp, Nagoya, Japan; Mamoru Nanasato, Sakakibara Heart Inst, Fuchu, Japan; Sachiko Inukai, Japanese Red Cross Nagoya Daini Hosp, Nagoya, Japan

4:30 PM

Board # 4133

Late Burden of VSD Repair on Pulmonary Function

Filip Eckerstrom, Marie Maagaard, Nicolai Boutrup, Aarhus Univ Hosp, Aarhus, Denmark; **Vibeke Hjortdal** , Rigshospitalet, Copenhagen, Denmark

4:30 PM

Board # 4134

Pregnancy Outcome in Women With Atrial Septal Defect: Associated With in-vitro Fertilization and Preeclampsia

Sebastian Udholm, Aarhus Univ Hosp, Aarhus N, Denmark; Louise Udholm, Rigshospitalet, Copenhagen, Denmark; Camilla Nyboe, Aarhus Univ Hosp, Aarhus N, Denmark; Ulrik Kesmodel, Aalborg Univ Hosp, Aalborg, Denmark; **Vibeke Hjortdal** , Rigshospitalet, Copenhagen, Denmark

4:30 PM

Board # 4135

Percutaneous Closure of Patent Foramen Ovale in Patients With Migraine - A Patient Level Meta-Analysis of PREMIUM and PRIMA Trials

**Preetham Kumar** , Hilary Shapiro, Brian West, Univ of California, Los Angeles, Los Angeles, CA; Heinrich Mattle, Bernhard Meier, Bern Univ Hosp, Bern, Switzerland; Andrew Charles, Jonathan M Tobis, Univ of California, Los Angeles, Los Angeles, CA

4:30 PM

Board # 4136

Impaired Executive Function in Adults With a Repaired Atrial Septal Defect

**Benjamin Asschenfeldt** , Aarhus Univ Hosp, Aarhus, Denmark; Lars Evald, Aarhus Univ, Hammel, Denmark; Simon Fristed Eskildsen, Aarhus Univ, Aarhus, Denmark; Johan Heiberg, Aarhus Univ Hosp, Aarhus, Denmark; Leif Østergaard, Vibeke Elisabeth Hjortdal, Aarhus Univ, Aarhus, Denmark

4:30 PM

Board # 4137

Bicuspid Aortic Valve Disease Increases Viscous Energy Loss, Circumferential Wall Shear Stress, and Pressure Drop in the Ascending Aorta

**Patrick Geeraert** , Jacqueline Flewitt, Michael Bristow, Bobak Heydari, Carmen Lydell, Libin Institue Univ of Calgary, Calgary, AB, Canada; Andrew G Howarth, Univ of Calgary, Calgary, AB, Canada; Ali Fatehi, Paul Fedak, James White, Libin Institue Univ of Calgary, Calgary, AB, Canada; Julio Garcia, Univ of Calgary, Calgary, AB, Canada

4:30 PM

Board # 4138

Worse Exercise Capacity With Age in VSD Patients?

Marie Maagaard, Aarhus Univ Hosp, Aarhus N; **Filip Eckerstrom** , Nicolai Boutrup, Aarhus Univ Hosp, Aarhus, Denmark; Vibeke Hjortdal, Rigshospitalet, Copenhagen, Denmark

4:30 PM

Poster Professor

Richard Krasuski, Durham, NC

# Abstract Poster Session

## PH.APS.05 - Stranger Things: Novel Mechanistic insights into PAH

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Poster Professor

Ralph Schermuly

4:30 PM

Board # 2254

Inactivation of Serca2 Redox Cysteine 674 Promotes Pulmonary Artery Remodeling by Activating Ire1á-xbp1 Pathway

**Weimin Yu** , Chongqing Univ, Chongqing, China; Li Xiao, Gang Liu, Xiaoyong Tong*

4:30 PM

Board # 2255

Dynamin 2, a Regulator of Mitochondrial Fission, is Upregulated in Human and Experimental Pulmonary Arterial Hypertension

**Asish Dasgupta** , Kuang-Hueih Chen, Lian Tian, Danchen Wu, Jeffrey D Mewburn, Patricia Da Lima, Stephen L Archer, Queen's Univ, Kingston, ON, Canada

4:30 PM

Board # 2256

A Protective Role for Nuclear Receptor Co-Activator 7 Deficiency in Pulmonary Arterial Hypertension

**Lloyd D Harvey** , Wei Sun, Vinny Negi, Adam Handen, Jingsi Zhao, Yi Yin Tai, Ying Tang, Univ of Pittsburgh, Pittsburgh, PA; Miranda Kay Culley, Univ of Pittsburgh SOM, Pittsburgh, PA; Raymond Benza, Allegheny General Hosp, Pittsburgh, PA; Stephen Y Chan, Univ of Pittsburgh, Pittsburgh, PA

4:30 PM

Board # 2257

Sur1/kir6.2 Potassium Channel a New Actor Involved in Pulmonary Arterial Hypertension

**Helene Le Ribeuz** , Angèle Boët, Mélanie Lambert, INSERM U999, Le Plessis Robinson, France; Wendy K Chung, Columbia Univ, New York, NY; David Montani, APHP Hop Bicetre INSERM, Le Kremlin-bicetre, France; Marc Humbert, Fabrice Antigny, INSERM U999, Le Plessis Robinson, France

4:30 PM

Board # 2258

Janus Activating Kinase 2 V617f Mutation Promotes Hypoxia Induced Pulmonary Hypertension in Mice

**Yusuke Kimishima** , Tomofumi Misaka, Tetsuro Yokokawa, Koichi Sugimoto, Keji Minakawa, Takafumi Ishida, Kazuhiko Ikeda, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima City, Japan

4:30 PM

Board # 2259

Crossing a Threshold of Lung Microvasculature Loss Triggers a Feed Forward Cycle of Endothelial Cell Injury Leading to Severe Pulmonary Arterial Hypertension in the Rat SU5416-hypoxia Model

**Ketul R Chaudhary** , Yupu Deng, Rafael Soares Godoy, Anli Yang, Katelynn R Rowe, Duncan J Stewart, Ottawa Hosp Res Inst, Ottawa, ON, Canada

4:30 PM

Board # 2260

Cxcl12 Activation Induces Pericyte Dissociation and Small Vessel Loss in PAH

**Ke Yuan** , Stanford Univ, Stanford, CA; Vinicio de Jesus Perez, Stanford Univ, Palo Alto, CA; Yu Liu, Stanford Univ, Stanford, CA; Abinaya Nathan, David Condon, Stanford Univ, Palo Alto, CA

4:30 PM

Board # 2261

Smooth Muscle-like Lymphangioleiomyomatosis Cells Induce Endothelial Cell Apoptosis and Network Disruption by the Release of Cytotoxic Mitochondria

**Mirabelle Sh Ho** , Miriel Ho, Lisa Julian, William L. Stanford, Duncan J Stewart, Ottawa Hosp Res Inst, Ottawa, ON, Canada

4:30 PM

Board # 2262

Pulmonary Venous and Arterial Remodeling in Experimental Group 2 Pulmonary Hypertension

**Michael S Sabbah** , Ahmed U Fayyaz, Leigh G Griffiths, William D Edwards, Surendra Dasari, Barry A Borlaug, Margaret M Redfield, Mayo Clinic, Rochester, MN

4:30 PM

Board # 2263

Scube1: A Novel BMPR2-related Pathogenic Effector in Pulmonary Endothelium and Potential Clinical Marker in Pulmonary Arterial Hypertension

**Wei Sun** , Ying Tang, Yi-Yin Tai, Adam Handen, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Seungchan Kim, Prairie View A and M Univ, Prairie View, TX; Yingze Zhang, Marc A Simon, Annie Watson, Yassmin Al Aaraj, John C Sembrat, Mauricio Rojas, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Gil Speyer, Arizona State Univ, Tempe, AZ; Stephen Y Chan, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA

# Abstract Poster Session

## SA.APS.03 - Surgical Therapy for Valvular Heart Disease

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 4273

Acquired Hemocompatibility of Bioprosthetic Heart Valve Results From Fibrin Deposition and Endothelial Covering in Human

Ulysse Richez, INSERM UMRS 1140, Paris, France; Christian Latremouille, Paris Descartes Univ, Paris, France; Ivan Netuka, Inst for Clinical and Experimental Med, Prague, Czech Republic; Jean Christian Roussel, Inst du Thorax - CTCV, Nantes Cedex 1, France; Peter Ivak, Inst for Clinical and Experimental Med, Prague, Czech Republic; Bruno Saubamea, Elisa Rossi, Paris Descartes Univ, Paris, France; Michel Kindo, Univ Hosp of Strasbourg, Strasbourg, France; Antoine Capel, Carmat SA, Velizy, France; Piet Jansen, Carmat SA, Vélizy-Villacoublay Cedex, France; Yury Pya, Natl Res Cardiac Surgery Ctr, Astana, Kazakhstan; Alain Carpentier, **David M Smadja** , Paris Descartes Univ, Paris, France

4:30 PM

Board # 4274

Oversizing in Sutureless Aortic Heart Valves Leads to Higher Gradients and Increased Pacemaker Rates

**Bart Meuris** , Michiel Marynissen, Laurence Verstraeten, Delphine Szecel, Peter Verbrugghe, KULeuven, Leuven, Belgium

4:30 PM

Board # 4275

Load Independent Parameters Indicate Early Contractile Dysfunction of the Left Ventricle Despite Preserved Ejection Fraction in an Experimental Model of Chronic Primary Mitral Regurgitation

**Daniella Corporan** , Roberto Hernandez-Merlo, Daisuke Onohara, Muralidhar Padala, Emory Univ, Atlanta, GA

4:30 PM

Board # 4276

Mitral Annular Calcification is Associated With Recurrent Mitral Regurgitation After Percutaneous Mitral Repair

**Vincent Chan** , David Messika-Zeitoun, Marino Labinaz, Donna Nicholson, Adam Dryden, Mark Hynes, Univ Ottawa Heart Inst, Ottawa, ON, Canada; Thierry G Mesana, Ottawa Heart Inst, Ottawa, ON, Canada; Benjamin Hibbert, Univ Ottawa Heart Inst, Ottawa, ON, Canada

4:30 PM

Board # 4277

External Support of the Cardiac Base Reduces Left Ventricular Size in Patients Undergoing BACE Procedure for Functional Mitral Regurgitation

**Jaishankar Raman** , OHSU, Portland, OR; Chandrashekar Padmanabhan, GKNM Hosp, Coimbatore, India; Richard Saldanha, KLE Hosp, Belagavi, India; Milind Hote, All India Inst of Medical Sciences, New Delhi, India; Philippe Pibarot, Hop Laval, Quebec City, QC, Canada

4:30 PM

Board # 4278

Transcatheter Aortic Valve Replacement Suppresses Postoperative Immune Responses

**Yohei Nomura** , Naoyuki Kimura, Akinori Aomatsu, Saitama Medical Ctr, Jichi Medical Univ, Saitama, Japan; Akio Matsuda, Natl Res Inst, Tokyo, Japan; Yusuke Imamura, Yosuke Taniguchi, Daijiro Hori, Saitama Medical Ctr, Jichi Medical Univ, Saitama, Japan; Manabu Shiraishi, Jichi Medical Univ, Saitama, Japan; Kenichi Sakakura, Saitama Medical Ctr, Jichi Medical Univ, Saitama, Japan; Hiroshi Wada, Jichi Medical Univ Omiya Med Cardiovscul, Saitama, Japan; Hideo Fujita, Jichi Medical Univ, Saitama, Japan; Yoshiyuki Morishita, Koichi Yuri, Saitama Medical Ctr, Jichi Medical Univ, Saitama, Japan; Kenji Matsumoto, Natl Res Inst for Child Health and Development, Tokyo, Japan; Atsushi Yamaguchi, Saitama Medical Ctr, Jichi Medical Univ, Saitama, Japan

4:30 PM

Board # 4279

Minimally Invasive Surgical Mitral Valve Repair of Secondary Mitral Regurgitation Improves Outcome in Non-Ischemic Heart Failure With Preserved Ejection Fraction

**Zsuzsanna Dorka Balogh** , Carlos Collet, Guy Van Camp, Cardiovascular Ctr OLV Aalst, Aalst, Belgium; Marc Vanderheyden, Jozef Bartunek, Cardiovascular Ctr, Aalst, Belgium; Monika Beles, Asim Katbeh, Marzia Albano, Evangelos Stefanidis, Cardiovascular Ctr OLV Aalst, Aalst, Belgium; Martin Penicka, Cardiovascular Ctr, OLV-Clinic Aalst, Aalst, Belgium

4:30 PM

Board # 4280

Need for Permanent Pacemaker Implantation and Long-Term Mortality After Isolated Surgical Aortic Valve Replacement: A State-Wide Analysis of 29,461 Patients

**Gil Moskowitz** , Gennaro Giustino, Icahn Sch of Med at Mount Sinai, New York, NY; Gorav Ailawadi, Univ of Virginia, Charlottesville, VA; Michael W. A. Chu, London Health Sciences Ctr, London, ON, Canada; A. Marc Gillinov, Cleveland Clinic, Cleveland, OH; Marissa Miller, Natl Heart Lung and Blood Inst, Bethesda, MD; Patrick T O'Gara, Brigham and Women's Hosp, Boston, MA; Wendy C Taddei-Peters, Natl Heart Lung and Blood Inst, Bethesda, MD; Anuradha Lala, Donna Marie Mancini, Mount Sinai Hosp, New York, NY; Joseph DeRose, Montefiore-Einstein Medical Ctr, Bronx, NY; Annetine C Gelijns, Alan J Moskowitz, Natalia Egorova, Icahn Sch of Med at Mount Sinai, New York, NY

4:30 PM

Board # 4281

Impact of Late Onset Mitral Regurgitation on Post-Ischemia Left Ventricular Remodeling in a Rodent Model

**Takanori Kono** , Daisuke Onohara, Daniella Corporan, Roberto Joel Hernandez-Merlo, Muralidhar Padala, Emory Univ, Atlanta, GA

4:30 PM

Board # 4282

**Biomechanical Analysis of Artificial Chordae Length in Mitral Valve Neochordoplasty Using a 3D Printed** Ex Vivo **Left Heart Simulator**

**Annabel Imbrie-Moore** , Michael J Paulsen, Stanford Univ, Stanford, CA; Haley Lucian, Stanford Univ, Palo Alto, CA; Camille Hironaka, Justin Farry, Hanjay Wang, Stanford Univ, Stanford, CA; Y Joseph Y Woo, Stanford Univ Sch Med, Stanford, CA

4:30 PM

Poster Professor

Tom C. Nguyen, Houston, TX

# Abstract Poster Session

## PH.APS.06 - The Rise and Rise of Epigenetics in Pulmonary Vascular Medicine

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 2264

Long Noncoding RNA Tykril Plays a Role in Pulmonary Hypertension by Controlling the p53 Mediated Regulation of PDGFRβ

Christoph M Zehendner, Goethe Univ, Frankfurt am Main, Germany; **Chanil Valasarajan** , Max Planck Inst for Heart and Lung Res, Bad Nauheim, Germany; Serge Thal, Johannes Gutenberg-Univ, Mainz, Germany; Astrid Werner, Goethe-Univ Frankfurt, Frankfurt, Germany; Jes-Niels Boeckel, Univ of Frankfurt, Frankfurt; Florian Christopher Bischoff, Inst of Cardiovascular Regeneration, Frankfurt am Main; David John, Goethe-Univ Frankfurt, Frankfurt, Germany; Tyler Weirick, Cardiovascular Innovation Inst, Louisville, KY; Simone-Franziska Glaser, Goethe Univ Frankfurt am Main, Frankfurt, Germany; Oliver Rossbach, Justus-Liebig-Univ Gießen, Giessen, Germany; Nicolas Jaé, Goethe-Univ Frankfurt, Frankfurt, Germany; Shemsi Demolli, Ctr for Molecular Med, Frankfurt am Main, Germany; Regina Hummel, Karl-Friedrich Kreitner, Christian Möllmann, Johannes Gutenberg-Univ, Mainz, Germany; Katharina Maria Michalik, Inst of Cardiovascular Regeneration, Frankfurt am Main; Wei Chen, Max-Delbrück-Centrum für Molekulare Med, Berlin, Germany; Werner Seeger, Max Planck Inst for Heart and Lung Res, Bad Nauheim, Germany; Shizuka Uchida, Goethe-Univ Frankfurt, Frankfurt, Germany; Andreas M Zeiher, Klinikum d. J. W Goethe-Univ, Frankfurt Am Main; Stefanie Dimmeler, Inst of Cardiovasular Regeneration, Frankfurt Am Main, Germany; Soni Pullamsetti, Max Planck Inst for Heart and Lung Res, Bad Nauheim, Germany

4:30 PM

Board # 2265

Epigenetic Factor CBP/p300 in Pulmonary Arterial Hypertension

**Alice Bourgeois** , CRIUCPQ, Laval Univ, Québec, QC, Canada; Karima Habbout, CRIUCPQ, Laval Univ, Quebec, QC, Canada; William Robert, Mark Orcholski, Sandra Breuils-Bonnet, Roxane Paulin, CRIUCPQ, Laval Univ, Québec, QC, Canada; Steeve Provencher, Sebastien Bonnet, Olivier Boucherat, CRIUCPQ, Laval Univ, Quebec, QC, Canada

4:30 PM

Board # 2266

Single-cell Transcriptomes Identify Abnormal Endothelial Subpopulation in Pulmonary Arterial Hypertension

**Zhiyu Dai** , Jingbo Dai, You-Yang Zhao, Northwestern Univ, Chicago, IL

4:30 PM

Board # 2268

Hypoxia-Driven Long Noncoding RNA KMT2E-AS1 Modulates Histone Methylation to Control Endothelial Metabolic Reprogramming and Pulmonary Hypertension

Qiujun Yu, Univ of Iowa Hosp, Iowa City, IA; **Yi Yin Tai** , Ying Tang, Jingsi Zhao, Vinny Negi, Adam L Handen, Catherine G Corey, Frances R Belmonte, Univ of Pittsburgh, Pittsburgh, PA; Brian Schwartz, Camp4 Therapeutics, Cambridge, MA; Balkrishen Bhat, Translate Bio, Lexington, MA; B. Nelson Chau, LogicBio Therapeutics, Cambridge, MA; Gil Speyer, Arizona State Univ, Tempe, AZ; Bing Wang, Sruti Shiva, Brett A Kaufman, Univ of Pittsburgh, Pittsburgh, PA; Seungchan Kim, Prairie View A&M Univ, Prairie View, TX; Thomas Bertero, Univ Côte d'Azur, Valbonne, France; Stephen Y Chan, Univ of Pittsburgh, Pittsburgh, PA

4:30 PM

Board # 2269

Epigenetic Reprogramming in Right Ventricular Fibroblasts Causes a Pyruvate Dehydrogenase Kinase-dependent Shift in Mitochondrial Metabolism and Promotes Fibrosis in Pulmonary Arterial Hypertension

**Lian Tian** , Danchen Wu, Asish Das Gupta, Kuang-Huieh Chen, Jeffery Mewburn, Francois Potus, Stephen L Archer, Queen's Univ, Kingston, ON, Canada

4:30 PM

Board # 2270

Crucial Role of Hypoxia in Epigenetic Changes of Pulmonary Artery SMCs From PAH With Bmpr2 Mutation

**Kazufumi Nakamura** , Okayama Univ, Okayama, Japan; Satoshi Akagi, Okayama Univ Hosp, okayama, Japan; Yukihiro Saito, Kentaro Ejiri, Toru Miyoshi, Masashi Yoshida, Satoshi Hirohata, Hiroshi Ito, Okayama Univ, Okayama, Japan

4:30 PM

Board # 2271

Hemodynamic Impact of Glucose-6-phosphate Dehydrogenase Inhibitor in Pulmonary Arterial Hypertension Model Mice

**Atsushi Kitagawa** , Sachin Gupte, New York Medical Coll, Valhalla, NY

4:30 PM

Board # 2272

The E2F1/Khps1/miR-1/Sphk1 Axis is Involved in Regulating Pulmonary Artery Smooth Muscle Cell Proliferation

**Yang Bai** , Angelia Denise Lockett, Marta Gomes, Alan B. Carneiro, Jones Nicole, Roberto F Machado, Indiana Univ, Indianapolis, IN

# Abstract Poster Session

## AT.APS.07 - Thrombosis and Hemostasis: Mechanisms, Outcomes and Treatment

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 1087

Endothelial LOX-1 Promotes Thrombosis Selectively In Inflammatory Condition

Akemi Kakino, Yoshiko Fujita, **Tatsuya Sawamura** , Shinshu Univ Sch Med, Matsumoto, Japan

4:30 PM

Board # 1088

Total Thrombus-formation Analysis System Can Predict 1-year Bleeding Events in Patients With Coronary Artery Disease

**Tatsuro Mitsuse** , Koichi Kaikita, Nobuhiro Nakanishi, Yuichiro Arima, Satomi Iwashita, Daisuke Sueta, Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

4:30 PM

Board # 1089

Fracture Resistance of Fibrin Clots

**Valerie Tutwiler** , Jaspreet Singh, Rustem I Litvinov, John Bassani, Prashant Purohit, Univ of Pennsylvania, Philadelphia, PA; John W Weisel, Philadelphia, PA

4:30 PM

Board # 1090

The Influence of Age on Viscoelastic Properties of the Thrombin-Induced Platelet-Fibrin Clot: A Potential Mechanism for Increased Thrombotic Risk in Older Adults

**Abdulla A Damluji** , Kevin Bliden, Behnam Tehrani, Inova Heart and Vascular Inst, Falls Church, VA; Henry A Tran, Weill Cornell Medical Coll, New York, NY; Rahul Chaudhary, Sinai Hosp of Baltimore, Baltimore, MD; Manila Jindal, Inova Heart, Falls Church, VA; Udaya Tantry, Sinai Hosp of Biltmore, Ellicott City, MD; Paul A Gurbel, Inova Heart and Vascular, Lutherville, MD

4:30 PM

Board # 1093

Thrombin Generation in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention

**Chen Gurevitz** , Alon Eisen, Rabin Medical Ctr, Petah Tikva, Israel; Eli Lev, Assuta Ashdod Medical Ctr, Ashdod, Israel; Osnat Itzhaki Ben Zadok, Leor Perl, Abed Samara, Ran Kornowski, Avishay Elis, Pia Raanani, Eti Ziv, Galia Spectre, Rabin Medical Ctr, Petah Tikva, Israel

# Abstract Poster Session

## CA.APS.01 - Ventricular Function: Mechanisms and Imaging

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 1117

The Search for Metrics of Systolic-Diastolic Coupling: Distance is Better Than Speed

**James MacNamara** , UT Southwestern, Dallas, TX; Vivek Koshti, Univ of Texas Southwestern, Dallas, TX; Katrin Dias, Christopher Hearon, IEEM, Dallas, TX; Erin Howden, Baker Heart and Diabetes Inst, Melbourne, Australia; Justin Lawley, Inst of Exercise and Environmental Med, Dallas, TX; Mildred A Opondo, Texas Health Presbyterian Hosp, Dallas, TX; William K Cornwell II, Univ of Colorado Anschutz Med, Aurora, CO; Marcus Anthony Urey, UTSW, Dallas, TX; Douglas Stoller, Univ of Texas Southwestern, Dallas, TX; Benjamin Levine, Inst of Exercise and Environmental Med, Dallas, TX; Satyam Sarma, IEEM UTSW, Dallas, TX

4:30 PM

Board # 1118

Electro-Mechanical Assessment of Left Ventricle Rotation

**Tomasz Jadczyk** , Medical Univ of Silesia, Div of Cardiology and Structural Heart Diseases, Katowice, Poland; Radoslaw Kurzelowski, Krzysztof Stanislaw Golba, Jacek Wilczek, Jolanta Biernat, Magdalena Cybulska, Medical Univ of Silesia, Katowice, Poland; Maximilian Y Emmert, Charite Univsmedizin Berlin, Berlin, Germany; Barbara Kalanska, Zofia Parma, Medical Univ of Silesia, Katowice, Poland; Mieczyslaw Dutka, Univ of Bielsko-Biala, Bielsko-Biala, Poland; Zdenek Starek, Intl Clinical Res Ctr, St. Anne's Univ Hosp Brno, Brno, Czech Republic; Wojciech Wojakowski, Medical Univ of Silesia, Katowice, Poland

4:30 PM

Board # 1119

Proton Therapy Preserves Acute Left Ventricular Ejection Fraction Relative to Conventional X-Ray-Based Therapy in Breast Cancer

**Shruti Siva Kumar** , Univ of Florida, Gainesville, FL; Julie Bradley, UF Health Proton Therapy Inst, Jacksonville, FL; Brandon Terracino, Univ of Florida, Gainesville, FL; Alex Waler, Univ of Central Florida, Jacksonville, FL; Eric Zeng, Univ of Florida, Gainesville, FL; Christopher Klassen, UF Health-Jacksonville, Jacksonville, FL; Michael Rutenberg, Xiaoying Liang, UF Health Proton Therapy Inst, Jacksonville, FL; Natalie Lockney, UF Health, Gainesville, FL; Raymond Mailhot, Nancy Mendenhall, UF Health Proton Therapy Inst, Jacksonville, FL; Walter O'Dell, Univ of Florida, Gainesville, FL

4:30 PM

Board # 1122

Evaluation of Intra-Left Ventricular Pressure Inversion Phenomenon During Early Diastole in Patients With Left Ventricular Aneurysm by Vector Flow Mapping

**Atsuko Uema** , Dokkyo Medical Univ Nikko MC, Tochigi, Japan; Yuki Nakatani, Dokkyo Medical Univ, Tochigi, Japan; Shoya Ono, Nagao Moeko, Masato Onozaki, Takushi Sugiyama, Megumi Hoshiai, Atsuhiko Kawabe, Hiroyuki Sugimura, Yasuto Horie, Takanori Yasu, Dokkyo Medical Univ Nikko MC, Tochigi, Japan

4:30 PM

Board # 1123

A Kaposi's Sarcoma-Associated Herpes Virus-Encoded microRNA Induces Dilated Cardiomyopathy

**Chen Chen** , Yanru Zhao, Tongji Hosp, Wuhan, China; Dao Wen Wang, Tongji Hosp, Wuhan

4:30 PM

Board # 1124

Human RVOT Transmural Arrhythmia Dynamics Under Parasympathetic and Sympathetic Stimulation

**Ndeye Rokhaya Faye** , George Washington Univ, Washington, DC

4:30 PM

Board # 1125

Intergenerational Transmission of Cardiac Dysfunction on a Mice Model of Maternal Obesity

**Suelen Zeca** , UFRuralRJ, Rio de Janeiro, Brazil; Olivia Hon, Milena Furtado, Nadia Rosenthal, The Jackson Lab, Bar Harbor, ME; Norma Almeida, UFRuralRJ, Rio de Janeiro, Brazil; Mauro Costa, The Jackson Lab, Bar Harbor, ME

# Abstract Poster Session

## CH.APS.08 - Where do Babies (with CHD) Come From? What's New in Fetal Cardiology

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 4:30 PM - 5:00 PM

4:30 PM

Board # 4111

Placental Oxygenation in Fetuses With and Without a Heart Defect

**Camilla Omann** , Mette Lauridsen, Aarhus Univ Hosp, Aarhus, Denmark; Steffen Ringgaard, Inst for Klinisk Medicin - The MR Res Ctr, Aarhus, Denmark; Zarmiga Karunanithi, Aarhus Univ Hosp, Aarhus N, Denmark; Vibeke Hjortdal, Rigshospitalet, Copenhagen, Denmark

4:30 PM

Board # 4112

Association of Socioeconomic and Geographic Factors on Short Term Outcomes in Fetuses With Prenatally Diagnosed Hypoplastic Left Heart Syndrome

**Anita Krishnan** , CNMC, Washington, DC; Marni Jacobs, Silver Spring, MD; Shaine A Morris, Texas Children's Hosp, Houston, TX; Shabnam Peyvandi, Univ California San Fran, San Francisco, CA; Aarti Bhat, Univ California San Fran, San Francisco, CA, Seattle, WA; Anjali Chelliah, Columbia Univ, New York, NY; Joanne Chiu, Johns Hopkins Univ, Baltimore, MD; Bettina F Cuneo, Childrens Hosp Colorado, Aurora, CO; Grace A Freire, Lisa Howley, All Childrens Hosp, St Petersburg, FL; Nazia Husain, Lurie Children's, Chicago, IL; Ann Kavanaugh-Mchugh, CNMC, Nashville, TN; Shelby Kutty, Johns Hopkins Med, Baltimore, MD; Caroline K Lee, Washington Univ of St. Louis, St. Louis, MO; Keila N Lopez, Baylor Coll of Med, Houston, TX; Angela McBrien, Univ of Alberta, Edmonton, AB, Canada; Erik Michelfelder, Sibley Heart Ctr Cardiology, Atlanta, GA; Nelangi M Pinto, Univ of Utah, Salt Lake Cty, UT; Kenan Stern, Mt Sinai Hosp, New York, NY; carolyn taylor, MUSC Children's Heart Program, Charleston, SC; Varsha Thakur, Stollery Children's Hosp, Edmonton, AB, Canada; Wayne Tworetzky, Boston Childrens Hosp, Boston, MA; Carol Wittlieb-Weber, Univ of Rochester Medical Cntr, Rochester, NY; Kristal Woldu, Columbia Presbyterian Hosp, New York, NY; Mary Teresa Donofrio, Childrens Natl Medical Ctr, Washington, DC

4:30 PM

Board # 4113

Prediction of Perinatal Outcomes in Fetuses With Ebstein's Anomaly or Tricuspid Valve Dysplasia

Tsukasa Torigoe, The Hosp for Sick Children, Toronto, ON, Canada; Lindsay R Freud, New York-Presbyterian Morgan Stanley Children's Hosp, New York, NY; Michael Puchalski, Primary Children's Hosp, Salt Lake City, UT; Anita L Szwast, Children's Hosp of Philadelphia, Philadelphia, PA; Grace A Freire, John Hopkin's All Children's Hosp, St Petersburg, FL; Ann K Kavanaugh-Mchugh, Vanderbilt Children's Hosp, Nashville, TN; Stephanie Levasseur, New York-Presbyterian Morgan Stanley Children's Hosp, New York, NY; Chun-Po Fan, The Hosp for Sick Children, Toronto, ON, Canada; Wayne Tworetzky, Boston Childrens Hosp, Boston, MA; **Edgar T Jaeggi** , The Hosp for Sick Children, Toronto, ON, Canada

4:30 PM

Board # 4114

Fetal Echocardiography Accuracy in Predicting Outcomes for Congenital Heart Disease Associated With Heterotaxy Syndrome

**Jennifer Romanowicz** , Pranava Sinha, Mary T Donofrio, Children's Natl Health System, Washington, DC; David N Schidlow, Boston Children's Hosp, Boston, MA

4:30 PM

Board # 4115

Success Rate of Fetal Aortic Valvuloplasty in Relation to Center Volumes: A Report From the International Fetal Cardiac Intervention Registry

Manon Gijtenbeek, Leiden Univ Medical Ctr, Leiden, Netherlands; **Shaine A Morris** , Texas Children's Hosp and Baylor Coll of Med, Houston, TX; Anita Moon-Grady, Univ. of California San Francisco, San Francisco, CA; Aimee K Armstrong, Nationwide Children's Hosp, Columbus, OH; Monica Cruz-Lemini, Children and Women's Specialty Hosp of Queretaro, Querétaro, Mexico; Joanna Dangel, Medical Univ of Warsaw, Warsaw, Poland; Stephen P Emery, UPMC Magee-Womens Hosp, Pittsburgh, PA; Alberto Galindo, Univ Hosp, Madrid, Spain; Sarah Gelehrter, C.S. Mott Children's Hosp, Ann Arbor, MI; Sofia Grinenco, Hosp Italiano de Buenos Aires, Buenos Aires, Argentina; Ulrike Herberg, Univ Hosp Bonn, Bonn, Germany; Edgar T Jaeggi, The Hosp for Sick Children, Toronto, ON, Canada; Sophie Malekzadeh-Milani, Necker Hosp, Paris, France; Simone Rolim Fernandes Fontes Pedra, Insto Dante Pazzanese de Cardio, Sao Paulo, Brazil; Jay D Pruetz, Children's Hosp Los Angeles, Los Angeles, CA; John Simpson, Evelina London Children's Hosp, London, United Kingdom; Haak C Monique, Leiden Univ Medical Ctr, Leiden, Netherlands; International Fetal Cardicac Intervention Registry

4:30 PM

Board # 4116

Non-Invasive, Remote, Self-Administered Acquisition of Fetal and Maternal ECG During Pregnancy

**Jack Rychik** , Childrens Hosp of Philadelphia, Philadelphia, PA; Steven Warsof, Eastern Virginia Medical Sch, Norfolk, VA; Sarah Schott, Christof Sohn, Univ Hosp, Heidelberg, Germany; Lorinne Levitt Rosen, Hadassah Univ Hosp Mount Scopus, Jerusalem, Israel; Nadav Schwartz, Perelman Sch of Med, Univ of Pennsylvania, Philadelphia, PA; Simcha Yagel, Hadassah Univ Hosp Mount Scopus, Jerusalem, Israel

4:30 PM

Board # 4117

Low Mortality Rate in Fetal Supraventricular Tachycardia: A 30-Year Single Institution Experience

**Edward T O'Leary** , Mark E Alexander, Vassilios J Bezzerides, Kevin G Friedman, Sarah S Pickard, Wayne Tworetzky, Douglas Y Mah, Boston Children's Hosp, Boston, MA

4:30 PM

Board # 4118

Perinatal Hypoxia Aggravates Occlusive Pulmonary Vasculopathy in the Adolescent Rats: Establishment of a Fatal Sugen/hypoxia Model and Its Molecular Basis

**Hironori Oshita** , Hirofumi Sawada, Mie Univ, Tsu City, Japan; Yoshihide Mitani, Mie Univ Graduate Sch Med, Tsu City, Japan; Jane Kabwe, Noriko Yodoya, Naoki Tsuboya, Kazunobu Ohya, Mie Univ, Tsu City, Japan; Hiroyuki Ohashi, Kazuo Maruyama, Masahiro Hirayama, Mie university, Tsu City, Japan

4:30 PM

Board # 4119

**Gestational Mild Intermittent Hyperoxia Has A Potential To Partly Rescue Murine Genetic Congenital Cardiac Anomalies Related To** Nkx2-5 **Mutation**

Cassandra Doll, Natalia Pereira, Mustafa Hashimi, Tabor Grindrod, Fariz Alkassis, **Hideko Kasahara** , Univ Florida, Gainesville, FL

4:30 PM

Board # 4120

Perinatal Coxsackievirus B4 Infection Leads To Preferential Damage Of The Left Ventricle

**Vipul Sharma** , Sara Nicole Rohrbough, Washington Univ in St. Louis, St. Louis, MO; Lisa S Goessling, Washington Univ in St. Louis, St.Louis, MO; Anoop K Brar, Washington Univ in St. Louis, Saint Louis, MO; Pirooz Eghtesady, Washington Univ in St. Louis, St Louis, MO

4:30 PM

Poster Professor

Bhawna Arya, Seattle, WA

# FIT Event

## FIT.02 - Developing your career in Pediatric Cardiology

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Saturday, November 16, 2019, 5:00 PM - 5:45 PM

This is not a CME/CE certified session

# Simulation

## SIM.07 - Clinical Diagnosis Using Ultrasound

#### Simulation Zone - Heart Hub, Hall C

### Saturday, November 16, 2019, 5:00 PM - 6:00 PM

5:00 PM

Invited Presenter

M Chadi M Alraies, Detroit, MI

# Abstract Rapid Fire Oral

## EA.RFO8 - AF Ablation: What Can We Do to Improve Safety and Effectiveness?

#### Zone 2, Science and Technology Hall

### Saturday, November 16, 2019, 5:10 PM - 6:00 PM

5:10 PM

Moderator

Moussa Mansour, Boston, MA

5:10 PM

Radiofrequency and Cryoballoon Ablation for Paroxysmal Atrial Fibrillation Produce Similar Durability of Pulmonary Vein Isolation and Effect on AF Burden (The RACE-AF Trial)

**Samuel K Sorensen** , Arne Johannessen, Rene Worck, Morten Hansen, Jim Hansen, Gentofte Hosp - Copenhagen Univ Hosp, Hellerup, Denmark

5:15 PM

Q & A

5:20 PM

Esophageal Thickness and Proximity to the Left Atrium Are Associated With Thermal Injury Following Catheter Ablation for Atrial Fibrillation

**Anne Kroman** , Sakher Sarairah, Univ of Washington, Seatte, WA; Suresh Kumar Kulandhaisamy, Univ of Washington, Seattle, WA; Nillubon Methachittiphan, Univ of Washington, Seatte, WA; Deanna Tregoning, Arun Raghav Mahankali Sridhar, Nazem W Akoum, Univ of Washington, Seattle, WA

5:25 PM

Q & A

5:30 PM

Safety and Efficacy of Atrial Fibrillation Ablation in Patients With Chronic Kidney Disease

**Amjad Abualsuod** , Indiana Univ, Indianapolis, IN; Fuad Habash, UAMS, Little Rock, AR; Khaldia Khaled, Louisiana State Univ, Shreveport, LA; Zaid Gheith, Bilal Alqam, Mohammed Eid Madmani, Srikanth Vallurupalli, UAMS, Little Rock, AR; Waddah Maskoun, Henry Ford Hosp, Detroit, MI

5:35 PM

Q & A

5:40 PM

Safety of Radiofrequency Ablation Without Pre-Procedural Trans-Esophageal Echocardiography in Patients With Atrial Fibrillation on Novel Oral Anticoagulants

**Mohamed Diab** , Oussama M Wazni, Khaldoun Tarakji, Walid I Saliba, Mohamed H Kanj, Daniel J Cantillon, John Rickard, Niraj Varma, Bruce L Wilkoff, Thomas Callahan, David O Martin, Mark J Niebauer, Thomas J Dresing, Bruce D Lindsay, Mina K Chung, Ayman Hussein, Cleveland Clinic, Cleveland, OH

5:45 PM

Q & A

5:50 PM

A Comparison of Vascular Access Closure Methods Following Atrial Fibrillation/Flutter Catheter Ablation: Insights From the Vascular Closure for Cardiac Ablation Registry (VACCAR)

**Sanjaya Gupta** , St. Luke's Mid-America Heart Inst, Lees Summit, MO; Mohammed Moghniuddin, Rigoberto Ramirez, St. Luke's Mid-America Heart Inst, Kansas City, MO; Omair Yousuf, St. Luke's Mid-America Heart Inst, Leawood, KS; Brian M Ramza, St. Luke's Mid-America Heart Inst, Mission Woods, KS; Michael Joseph Giocondo, Daniel Steinhaus, Alan P Wimmer, St. Luke's Mid-America Heart Inst, Kansas City, MO

5:55 PM

Q & A

# Abstract Rapid Fire Oral

## EP.RFO16 - Evolving Role of Coronary Artery Calcium in CVD Risk Prediction

#### Science and Technology Hall A, Booth 605, Level 2

### Saturday, November 16, 2019, 5:10 PM - 6:00 PM

5:10 PM

Moderator

Amit Khera, Dallas, TX

5:10 PM

Coronary Artery Calcium Among Adults With Borderline ASCVD Risk (5-7.5%): The Coronary Artery Calcium Consortium

**S M Iftekhar Uddin** , Albert D. Osei, Sina Kianoush, Olusola Orimoloye, Johns Hopkins Sch of Med, Baltimore, MD; Mohammadhassan Mirbolouk, Johns Hopkins Medical Inst, Baltimore, MD; Zeina Dardari, Johns Hopkins Univ Sch of Med, Baltimore, MD; Omar Dzaye, Johns Hopkins Univ, Baltimore, MD; Michael Miedema, Minneapolis Heart Inst, Minneapolis, MN; John Rumberger, Princeton Longevity Ctr, Fairfax, VA; Leslee Shaw, Weil Cornell Medical Coll, New York, NY; Daniel Berman, Cedars-Sinai Medical Ctr, Los Angeles, CA; Michael Budoff, David Geffen Sch of Med, UCLA, Los Angeles, CA; Alan Rozanski, The Mount Sinai Hosp, New York, NY; Khurram Nasir, Baptist Health South Florida, New Haven, CT; Michael J Blaha, Johns Hopkins Univ, Baltimore, MD

5:15 PM

Q & A

5:20 PM

Coronary Artery Calcium Testing to Guide Statin Allocation According to ASCVD Risk-enhancing Factors: Results From The Multi-ethnic Study of Atherosclerosis (MESA)

**Ramzi Dudum** , Johns Hopkins Hosp, Baltimore, MD; Jaideep Patel, VCU Medical Ctr, Richmond, VA; John W McEvoy, Natl Univ of Ireland, Galway, Ireland; Roger S Blumenthal, Johns Hopkins Hosp, Baltimore, MD; Salim S Virani, Michael E Debakey VA-Baylor, Bellaire, TX; Michael D Miedema, MINNEAPOLIS HEART INSTI, Minneapolis, MN; Steven Shea, COLUMBIA UNIVERSITY, New York, NY; Joseph Yeboah, WAKE FOREST UNIVERSITY, Winston Salem, NC; Philip Greenland, FEINBERG SCH OF MEDICINE, Chicago, IL; Antonio Abbate, VIRGINIA COMMONWEALTH UNIVERSITY, Richmond, VA; William G Hundley, WAKE FOREST UNIVERSITY SCHOOL MED, Winston Salem, NC; Khurram Nasir, BAPTIST HEALTH SOUTH FLORIDA, New Haven, CT; Amy Karger, Univ of Minnesota, Minneapolis, MN; Michael Y Tsai, UNIVERSITY MINNESOTA, Minneapolis, MN; Michael J Blaha, JOHNS HOPKINS HOSPITAL, Baltimore, MD; Mahmoud S Al Rifai, Univ of Kansas, Wichita, KS

5:25 PM

Q & A

5:30 PM

Association of Coronary Artery Calcium With Atherosclerotic Cardiovascular Disease versus Bleeding Risk- Implications for Aspirin Use: The Dallas Heart Study

**Ezimamaka Ajufo** , Colby R Ayers, Rebecca Vigen, Parag H. Joshi, Anand Rohatgi, James A. de Lemos, Amit Khera, Univ of Texas Southwestern, Dallas, TX

5:35 PM

Q & A

5:40 PM

Coronary Artery Calcifications in a Low Risk Population

**Manasi Tannu** , Emory Univ Hosp, Atlanta, GA; Feng-Chang Lin, Univ of North Carolina at Cha, Chapel Hill, NC; Laura Tuttle, Emily Olsson, Univ of North Carolina at Chapel Hill, Chapel Hill, NC; Alan Hinderliter, Univ North Carolina, Chapel Hill, NC; Larry Klein, Univ of North Carolina at Chapel Hill, Chapel Hill, NC; Anthony J Viera, Duke Univ, Durham, NC

5:45 PM

Q & A

5:50 PM

Prevalence and Predictors of Coronary Artery Calcium (CAC) Among Very Young Patients Between 20-30 Years Old: The Coronary Artery Calcium Consortium

**Albert D Osei** , Johns Hopkins Univ, Baltimore, MD; S. M Iftekhar Uddin, Johns Hopkins Univ, Baltimore, MD; Sina Kianoush, Yale Univ, Waterbury, CT; Mohammadhassan Mirbolouk, Johns Hopkins Medical Inst, Baltimore, MD; Olusola Orimoloye, Omar Dzaye, Zeina Dardari, Johns Hopkins Univ, Baltimore, MD; Leslee Shaw, Weill Cornell Med, New York, NY; John A Rumberger, The Princeton Longevity Ctr, Hopewell, NJ; Daniel Berman, The Princeton Longevity Ctr, Hopewell, NJ, Los Angeles, CA; Michael D Miedema, Allina Health, Minneapolis, MN; Matthew J Budoff, Los Angeles Biomedical Res, Torrance, CA; Vasan S Ramachandran, Framingham Heart Insitute, Framingham, MA; Khurram Nasir, Baptist Health South Florida, New Haven, CT; Michael J Blaha, Johns Hopkins Univ, Baltimore, MD

5:55 PM

Q & A

# Abstract Rapid Fire Oral

## AT.RFO4 - Mechanistic Insights into the Role of Inflammation in Metabolism and Atherosclerosis

#### Zone 1, Science and Technology Hall

### Saturday, November 16, 2019, 5:10 PM - 6:00 PM

5:10 PM

NLRP3 Inflammasome Activation Regulates PCSK9 Secretion: Role Of IL-1β

**Zufeng Ding** , Univ of Arkansas for Medical Sciences, Little Rock, AR; Jawahar L Mehta, Univ of Arkansas for Medical Sci, Little Rock, AR

5:15 PM

Q & A

5:20 PM

Disturbed Flow-induced Acetylation of Copper Chaperone Atox1 via Oxidative Inactivation of Sirt1 Promotes Inflammation and Atherosclerosis

**Sudhahar Varadarajan** , Archita Das, Med. Coll. of Georgia at Augusta Univ, Augusta, GA; Hanjoong Jo, Emory Univ, Atlanta, GA; Jun-ichi Abe, MD Anderson Cancer Ctr, Houston, TX; Masuko Ushio-Fukai, Tohru Fukai, Med. Coll. of Georgia at Augusta Univ, Augusta, GA

5:25 PM

Q & A

5:30 PM

Hepatic Fat Associates With Increased Arterial Inflammation: Novel Insights Linking Liver Adiposity to Cardiovascular Diseases

**Tawseef Dar** , Massachusetts General Hosp, Boston, MA; Shady Abohashem, Massachusetts General Hosp-HMS, Revere, MA; Azar Radfar, MGH, Boston, MA; Nicki Naddaf, Michael T Osborne, Ahmed A Tawakol, Massachusetts General Hosp, Boston, MA

5:35 PM

Q & A

5:40 PM

Adipose Tissue Ceramides Reduces Endothelium-Dependent Vasorelaxation, Amplifies Vascular Oxidative Stress & Induces Systemic Inflammation Ultimately Leading To Death In Coronary Artery Disease

**Nadia Akawi** , Univ of Oxford, Oxford, United Kingdom; Antonio Checa, Karolinska Instt, Stockholm, Sweden; Ioannis Akoumianakis, Marios Margaritis, Christos P. Kotanidis, Univ of Oxford, Oxford, United Kingdom; Evangelia Daskalakis, Karolinska Instt, Stockholm, Sweden; Hidekazu Kondo, Univ of Oxford, Oxford, United Kingdom; Keith M Channon, Univ of Oxford, Oxford; Craig Wheelock, Karolinska Instt, Stockholm, Sweden; Charalambos Antoniades, Univ of Oxford, Oxford, United Kingdom

5:45 PM

Q & A

5:50 PM

IL-19, a Novel Adipokine With Insulin Sensitizing Action

Christine Vrakas, Tatsuo Kawai, Sheri E Kelemen, Michael Autieri, Gavin Landesberg, **Rosario G Scalia** , Temple Univ, Philadelphia, PA

5:55 PM

Q & A

# Abstract Rapid Fire Oral

## HF.RFO12 - The Best in Outcome in Heart Failure

#### Zone 4, Science and Technology Hall

### Saturday, November 16, 2019, 5:10 PM - 6:00 PM

5:10 PM

Heart Failure and Albuminuria During Hospitalization With ACS and Long Term Mortality Risk. The ABC Study on Acute Coronary Syndrome

Heba T Mahmoud, The ABC Heart Disease Fndn, Conegliano, Italy; **Giuseppe Berton** , Conegliano General Hosp, Conegliano, Italy; Rosa Palmieri, Adria General Hosp, Conegliano, Italy; Francesco Bagato, Feltre General Hosp., Feltre, Italy; Rocco Cordiano, Adria General Hosp, Adria, Italy; Elisabetta Lorenzon, The ABC Heart Disease Fndn, Conegliano, Italy; Fiorella Cavuto, Bassano del grappa General Hosp., Bassano del grappa, Italy; Moemen M Mahmoud, Minia Univ Hosp, Minia, Egypt

5:15 PM

Q & A

5:20 PM

The Prognostic Value of the NAFLD Fibrosis Score on Outcomes in Heart Failure With Preserved Ejection Fraction: An Analysis of the TOPCAT Study

**Anupam A Kumar** , Vanderbilt Univ Sch of Med, Nashville, TN; Stuart Prenner, Univ of Pennsylvania, Philadephia, PA; Stacey Prenner, Julio A Chirinos, Univ of Pennsylvania, Philadelphia, PA

5:25 PM

Q & A

5:30 PM

Advance Care Planning and Prognosis Education in Patients With Heart Failure: Insights from the NCDR PINNACLE Registry

**Casey E Cavanagh** , Lindsey Rosman, Philip Chui, Yale Sch of Med, New Haven, CT; Karl E Minges, Yale Univ, New Haven, CT; Nihar R. Desai, Yale Sch of Med, New Haven, CT; Sarah Goodlin, VA Portland HCS, Portland, OR; Savitri Fedson, Baylor Coll of Med, Houston, TX; John A Spertus, Mid America Heart Inst, Kansas City, MO; Ty J Gluckman, Providence Heart Inst, Portland, OR; Yang Song, Baim Inst for Clinical Res, Boston, MA; Alexander Turchin, Brigham and Women's Hosp, Boston, MA; Gheorghe Doros, Jane J Lee, Baim Inst for Clinical Res, Boston, MA; Matthew M Burg, Yale Sch of Med, New Haven, CT

5:35 PM

Q & A

5:40 PM

A Novel Approach to Managing Heart Failure Populations Using Actionable Machine Learning Models

**Linyuan Jing** , Alvaro Ulloa Cerna, Geisinger, Danville, PA; Christopher Good, Medicor Associates, Inc, Erie, PA; Nathan M Sauers, Dustin N Hartzel, Joseph B Leader, H Lester Kirchner, Yirui Hu, David M Riviello, Geisinger, Danville, PA; Joshua Victor Stough, Bucknell Univ, Lewisburg, PA; Seth Gazes, Allyson Haggerty, Sushravya Raghunath, Brendan J Carry, Geisinger, Danville, PA; Christopher M Haggerty, Geisinger Health System, Danville, PA; Brandon K Fornwalt, Geisinger, Danville, PA

5:45 PM

Q & A

5:50 PM

Foregone and Delayed Medical Care is Associated With Increased Health Care Costs and Utilization Among Heart Failure Patients in the United States

**Alexander W Thomas** , Yale Sch of Med, New Haven, CT; Javier Valero-Elizondo, Yale Univ, New Haven, CT; Rohan Khera, UT Southwestern Medical Ctr, Dallas, TX; Haider Javed Warraich, Duke Univ Medical Ctr, Durham, NC; Harlan M Krumholz, Yale Univ Schl Med, New Haven, CT; Khurram Nasir, Nihar R. Desai, Yale Sch of Med, New Haven, CT

5:55 PM

Q & A

# Moderated Digital Posters

## AC.MDP3 - Biomarkers I

#### Moderated Posters 1, Science and Technology Hall

### Saturday, November 16, 2019, 5:10 PM - 6:00 PM

5:10 PM

Moderator

James A De Lemos, Dallas, TX

5:10 PM

Diagnostic Performance of a Novel High-sensitivity Cardiac Troponin I Assay: The Westcor Study

**Hilde Lunde Lunde Tjora** , Ole-Thomas Steiro, Jørund Langørgen, Haukeland Univ Hosp, Bergen, Norway; Ottar Kjell Nygard, Rune Oskar Bjørneklett, Haukeland Univ Hosp/Univ of Bergen, Bergen, Norway; Renstrom Renate, Haukeland Univ Hosp, Bergen, Norway; Øyvind Skadberg, Stavanger Univ Hosp, Stavanger, Norway; Vernon V S V.s Bonarjee, Stavanger Univ Hosp, Stavanger, Norway; Clare Hunt, Paul Collinson, St George's Univ Hosp NHS Fndn Trust, London, United Kingdom; Torbjørn Omland, Akershus Uiversity Hosp /Univ of Oslo, Oslo, Norway; Kjell Vikenes, Kristin Moberg Aakre, Haukeland Univ Hosp/Univ of Bergen, Bergen, Norway

5:15 PM

Q & A

5:20 PM

Defining Prognostically Significant Perioperative Myocardial Injury During CABG Surgery Using hs-Troponin T - Insights From the ERICCA Trial

**Vikram Sharma** , Cleveland Clinic, Cleveland, OH; Huili Zheng, Natl Registry of Diseases, Singapore, Singapore; Heerajnarain Bulluck, Golden Jubilee Natl Hosp, Clydebank, United Kingdom; Jennifer Nicholas, Tim Clayton, London Sch of Hygiene & Tropical Med, London, United Kingdom; Derek M Yellon, Derek J Hausenloy, The Hatter Cardiovascular Inst, London, United Kingdom

5:25 PM

Q & A

5:30 PM

Fibroblast Growth Factor 23 and Mortality in Patients With Suspected or Known Coronary Artery Disease: From the ANOX Study

**Hiromichi Wada** , Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan; Kazuhiko Kotani, Jichi Medical Univ, Shimotsuke, Japan; Masahiro Suzuki, Natl Hosp Organization Saitama Hosp, Wako, Japan; Morihiro Matsuda, Natl Hosp Organization Kure Medical Ctr and Chugoku Cancer Ctr, Kure, Japan; Yoichi Ajiro, Natl Hosp Organization Yokohama Medical Ctr, Yokohama, Japan; Tsuyoshi Shinozaki, Natl Hosp Organization Sendai Medical Ctr, Sendai, Japan; Satoru Sakagami, Natl Hosp Organization Kanazawa Medical Ctr, Kanazawa, Japan; Kazuya Yonezawa, Natl Hosp Organization Hakodate Natl Hosp, Hakodate, Japan; Masatoshi Shimizu, Natl Hosp Organization Kobe Medical Ctr, Kobe, Japan; Junichi Funada, Natl Hosp Organization Ehime Medical Ctr, Toon, Japan; Takashi Takenaka, Natl Hosp Organization Hokkaido Medical Ctr, Sapporo, Japan; Yukiko Morita, Natl Hosp Organization Sagamihara Natl Hosp, Sagamihara, Japan; Toshihiro Nakamura, Natl Hosp Organization Kyushu Medical Ctr, Fukuoka, Japan; Kazuteru Fujimoto, Natl Hosp Organization Kumamoto Medical Ctr, Kumamoto, Japan; Hiromi Matsubara, Natl Hosp Organization Okayama Medical Ctr, Okayama, Japan; Toru Kato, Natl Hosp Organization Tochigi Medical Ctr, Utsunomiya, Japan; Takashi Unoki, Daisuke Takagi, Kyohma Wada, Miyaka Wada, Moritake Iguchi, Nobutoyo Masunaga, Mitsuru Ishii, Mitsuru Abe, Masaharu Akao, Koji Hasegawa, Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan

5:35 PM

Q & A

5:40 PM

Diagnostic Utility And Pathogenic Role of Circulating Micrornas in Vasospastic Angina

**Chan Soon Park** , Korea Advanced Inst of Science, Daejeon, Korea, Republic of; Inho Kim, Gyu Chul Oh, Jung-Kyu Han, Han-Mo Yang, Kyung Woo Park, Hyun-Jai Cho, Hyun-Jae Kang, Seoul Natl Univ Hosp, Seoul, Korea, Republic of; Bon-Kwon Koo, Stanford Univiersity, Stanford, CA; Woo-Young Chung, Seoul Metropolitan Government Seoul Natl Univ Boramae Medical Ctr, Seoul, Korea, Republic of; Seil Oh, Hae-Young Lee, Seoul Natl Univ Hosp, Seoul, Korea, Republic of

5:45 PM

Q & A

5:50 PM

Excessive Inflammation Reaction After Acute Myocardial Infarction: Predictive Role of Early CRP Values for One Year Mortality

**Ahmad Alkouri** , Axel Linke, Christian Pfluecke, Heart Ctr Dresden Univ Clinic, Dresden, Germany

5:55 PM

Q & A

# Moderated Digital Posters

## IM.MDP9 - CT of Coronary Artery Plaque: Taking Imaging to the Next Level

#### Moderated Posters 3, Science and Technology Hall

### Saturday, November 16, 2019, 5:10 PM - 6:00 PM

5:10 PM

**The Limitation of Computed Tomographic Coronary Angiography Imaging to Identify Coronary Lipid-Rich Atheroma** In Vivo **: Insights Fromcomputed Tomographic Coronary Angiography Andnear-Infrared Spectroscopy Analysis**

**Satoshi Kitahara** , Natl Cerebral and Cardiovascular Ctr, Suita Osaka, Japan; Yu Kataoka, Hiroyuki Miura, Satoshi Honda, Masashi Fujino, Hayato HOSODA, Kazuhiro nakao, Shuichi Yoneda, Fumiyuki Otsuka, Natl Cerebral and Cardiovascular Ctr, Suita, Osaka, Japan; Tomoaki Kanaya, Dokkyo Medical Univ Hosp, Tochigi, Japan; Nishihira Kensaku, Natl Cerebral and Cardiovascular Ctr, Miyazaki, Miyazaki, Japan; Yasuhide Asaumi, Natl Cerebral and Cardiovascular Ctr, Suita, Osaka, Japan; Teruo Noguchi, Natl Cerebral & Cardiovascular Ctr, Suita, Osaka, Japan; Satoshi Yasuda, Natl Cerebral and Cardiovascular Ctr, Suita, Osaka, Japan; Takahiro Nakashima, NCVC, Suita, Japan

5:15 PM

Q & A

5:20 PM

Coronary Vessel Disease and Correlation With Coronary Lumen Volume in Diabetics

**Shiela Beroukhim Afrahimi** , Kashif Shaikh, April Kinninger, Harbor UCLA Medical Ctr, Torrance, CA; Matthew J Budoff, Los Angeles Biomedical Res, Torrance, CA; Sion K Roy, Harbor UCLA Medical Ctr, Torrance, CA

5:25 PM

Q & A

5:30 PM

Treatment of Psoriasis With Biologic Therapy is Associated With Regression of Coronary Artery Plaque Necrotic Core and Positive Remodeling: Results From a Prospective, Observational Pilot Study

**Harry Choi** , Natl Heart Lung and Blood Inst, Bethesda, MD; Milena Aksentijevich, Amit K. Dey, NHLBI, Bethesda, MD; Colin Scott, Natl Heart Lung and Blood Inst, Bethesda, MD; Justin A. Rodante, NHLBI, Bethesda, MD; Youssef Elnabawi, Natl Heart Lung and Blood Inst, Bethesda, MD; Noor O. Khalil, NHLBI, Bethesda, MD; Danish Akbar, DermAssociates, Silver Spring, MD; Mina Al Najafi, Paula Anzenberg, Jenis Argueta-Amaya, NHLBI, Bethesda, MD; Andrew Keel, Natl Heart Lung and Blood Inst, Bethesda, MD; Heather Teague, Natl Heart Lung and Blood Inst, Rockville, MD; Martin Playford, Natl Insts of Health, Bethesda, MD; Joel Gelfand, Univ of Pennsylvania, PHILADELPHIA, PA; Marcus Y. Chen, NHLBI, Bethesda, MD; David A Bluemke, UW Madison Hosp, Madison, WI; Andrew Buckler, Elucid Bioimaging Inc., Wenham, MA; Nehal N Mehta, NIH, Bethesda, MD

5:35 PM

Q & A

5:40 PM

Absence of Coronary Artery Calcification in Heterozygous Familial Hypercholesterolemia: A Systematic Review and Pooled-analysis of Published Studies

**Reed Mszar** , Yale Sch of Public Health, New Haven, CT; Gowtham R. Grandhi, Javier Valero-Elizondo, Ctr for Outcomes Res and Evaluation, New Haven, CT; Salim S Virani, Michael E. Debakey VA-Baylor, Bellaire, TX; Ron Blankstein, Brigham and Women's Hosp, Boston, MA; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; Leopoldo Pérez de Isla, Hosp Clínico San Carlos, Madrid, Spain; Pedro Mata, Spanish Familial Hypercholesterolemia Fndn, Madrid, Spain; Khalid Al Rasadi, Sultan Qaboos Univ, Muscat, Oman; Harlan M Krumholz, Yale Univ Sch of Med, New Haven, CT; Raul D. Santos, Univ of Sao Paulo Medical Sch Hosp, Sao Paulo, Brazil; Khurram Nasir, Ctr for Outcomes Res and Evaluation, New Haven, CT

5:45 PM

Q & A

5:50 PM

Relationship Between Epicardial Fat Volume and Density With Obstructive Sleep Apnea and Coronary Plaque Burden

**Jordan Andrews** , SAHMRI, Adelaide, Australia; Nitesh Nerlekar, Vivek Gupta, MonashHeart, Clayton, Australia; Lin Mo, Monash Health, Clayton, Australia; James Donald Cameron, Monash Cardiovascular Res Cent, Clayton, Australia; Sujith Seneviratne, Andrew Lin, MonashHeart, Clayton, Australia; Jeremy Yuvara, MonashHeart, Adelaide, Australia; Gijo Thomas, SAHMRI, Adelaide, Australia; Garun S Hamilton, Monash Medical Ctr, Clayton, Australia; Stephen Nicholls, Monash, Hyde Park, Australia; Dennis T Wong, Royal Adelaide Hosp, Adelaide, Australia

5:55 PM

Q & A

# Moderated Digital Posters

## EA.MDP6 - Device Infection: Prevention and Management

#### Moderated Posters 2, Science and Technology Hall

### Saturday, November 16, 2019, 5:10 PM - 6:00 PM

5:10 PM

Moderator

Jude francis Clancy, New Haven, CT

5:10 PM

Comparison of Outcomes of Transvenous Lead Extraction Using an Excimer Laser Sheath vs the Tightrail Rotating Dilator Sheath

**Satish Misra** , Kamala Swayampakala, Tricia Coons, Claire Cerbie, Magdalena Lesiczka, John W Holshouser, Rohit Mehta, Sanger Heart and Vascular Inst, Charlotte, NC

5:15 PM

Q & A

5:20 PM

Staphylococcus Aureus Infection Predicts Repeat Infection And Worse Prognosis After Extraction Of Infected Cardiovascular Implantable Electronic Device

**Ryohsuke Narui** , Ikutaro Nakajima, Caleb Norton, Eun-Jeong Kim, Vanderbilt Univ Medical Ctr, Nashville, TN; Benjamin B Holmes, Vanderbilt Univ Med. Ctr, Nashville, TN; William G Stevenson, Christopher R Ellis, George H Crossley, Jay A Montgomery, Vanderbilt Univ Medical Ctr, Nashville, TN

5:25 PM

Q & A

5:30 PM

Pre-Procedure Factors Predict Technically-Challenging Cardiovascular Implantable Device Lead Extraction

**Stephanie L Stovall** , Jared David Miller, Oregon Health & Science Univ, Portland, OR; Peter Jessel, OHSU, Portland, OR; Charles Henrikson, Oregon Health & Science Univ, Portland, OR

5:35 PM

Q & A

5:40 PM

Usefulness of CONUT Score as a Predictor of Bacteremia Associated With Device Pocket Infection

**Tomoaki Nakano** , Osaka Univ Graduation Sch of Med, Suita, Japan; Hitoshi Minamiguchi, Osaka Univ Graduation Sch of Med, Suita Osaka, Japan; Kentaro Ozu, Osaka Univ Graduation Sch of Med, Osaka, Japan; Akihiro Sunaga, Osaka university, Suita, Japan; Isamu Mizote, Osaka Univ Graduate Sch of Med, Suita, Osaka, Japan; Tomohito Ohtani, Hiroya Mizuno, Osaka Univ, Suita, Japan; Shungo Hikoso, Yasushi Sakata, Osaka Univ Graduation Sch of Med, Suita, Japan

5:45 PM

Q & A

5:50 PM

Antibacterial Envelope is Associated With a Decreased Risk of Cardiac Implantable Electronic Device Infections: An Updated Meta-Analysis

Chol Techorueangwiwat, Jakrin Kewcharoen, **Pattara Rattanawong** , Univ of Hawaii, Honolulu, HI

5:55 PM

Q & A

# Moderated Digital Posters

## GE.MDP18 - DMD

#### Moderated Posters 6, Science and Technology Hall

### Saturday, November 16, 2019, 5:10 PM - 6:00 PM

5:10 PM

Connexin-43 Reduction Rescues Cardiac and Skeletal Muscle Pathology in a Mouse Model of Duchenne Muscular Dystrophy Symptomatic Carriers

**Julie Nouet** , Eric Himelman, Kevin C Lahey, Rutgers Univ, Newark, NJ; Patrick Gonzalez, Rutgers New Jersey Medical Sch, Newark, NJ; Qingshi Zhao, New Jersey Medical Sch Rutgers, Newark, NJ; Diego Fraidenraich, Rutgers - NJMS, Newark, NJ

5:15 PM

Q & A

5:25 PM

Q & A

5:30 PM

Pim-1 Up-Regulation Exerts Mitochondrial Protection in a Cell Model of Duchenne Muscular Dystrophy-Cardiomyopathy

**Leah Thomas** , Medical Coll Wisconsin, Milwaukee, WI; Melanie Gartz, Medical Coll of Wisconsin, Milwaukee, WI; Mark Alan Sussman, San Diego State Univ, San Diego, CA; Jennifer L Strande, Medical Coll Wisconsin, Milwaukee, WI

5:35 PM

Q & A

5:40 PM

Genetic Prevention of Connexin-43 Remodeling Protects Duchenne Muscular Dystrophy Mice From Cardiomyopathy

**Eric Himelman** , Mauricio Lillo Gallardo, Julie Nouet, Patrick Gonzalez, Rutgers Univ, Newark, NJ; Qingshi Zhao, New Jersey Medical Sch Rutgers, Newark, NJ; Lai-Hua Xie, Hong Li, Tong Liu, Rutgers Univ, Newark, NJ; Paul Lampe, Fred Hutchinson Cancer Res Ctr, Seattle, WA; Glenn I Fishman, Natalia Shirokova, New York Univ Medical Ctr, New York, NY; Jorge Contreras, Diego Fraidenraich, Rutgers - NJMS, Newark, NJ

5:45 PM

Q & A

5:50 PM

Cardioprotective Effect of Nicorandil on Dystrophin Deficient Cardiomyopathy in the Mdx Mouse Model

**Rachel T Sullivan** , Ngoc Lam, Margaret Haberman, Muhammad Z Afzal, Medical Coll of Wisconsin, Wauwatosa, WI; Jennifer L Strande, Medical Coll of Wisconsin, Milwaukee, WI

5:55 PM

Q & A

# Moderated Digital Posters

## AT.MDP15 - Hemostasis, Thrombosis and Fibrinolysis

#### Moderated Posters 5, Science and Technology Hall

### Saturday, November 16, 2019, 5:10 PM - 6:00 PM

5:10 PM

Moderator

Xiaoping Du, Chicago, IL

5:10 PM

Hindered Transport of Platelet Agonists and Coagulation Factors in the Narrow Gaps Between Platelets is a Regulator of the Hemostatic Response to Injury

Timothy J Stalker, Univ Pennsylvania, Philadelphia, PA; Irina D Pokrovskaya, Brian Storrie, Univ of Arkansas for Medical Sciences, Little Rock, AR; Lawrence Brass, Talid Sinno, **Maurizio Tomaiuolo** , Univ of Pennsylvania, Philadelphia, PA

5:15 PM

Q & A

5:20 PM

Exploring the Reciprocal Relationship Between the Intrinsic Tenase and Platelets During Hemostasis in vivo

Maurizio Tomaiuolo, **Timothy J Stalker** , Univ of Pennsylvania, Philadelphia, PA

5:25 PM

Q & A

5:30 PM

Development and Characterization of Novel Humanized PAR4 Transgenic Mice

**Stephanie A Holmes** , Thomas Jefferson Univ, Philadelphia, PA; Paul F Bray, Univ of Utah, Salt Lake City, UT; Leonard C Edelstein, Steven E McKenzie, Thomas Jefferson Univ, Philadelphia, PA

5:35 PM

Q & A

5:40 PM

Indoleamine 2,3-Dioxygenase-1, a Novel Therapeutic Target in Thrombotic Uremic Toxicity

**Joshua A Walker** , Boston Univ Boston Medical Ctr, Boston, MA; Sean Richards, Boston Medical Ctr, Boston, MA; Mostafa Belghasem, Boston Medical Ctr, Boston, MA, Boston, MA; Nkiruka Arinze, Boston Medical Ctr, Boston, MA; Stephen Whelan, Boston Univeristy, Boston, MA; Norman Lee, Boston Univ, Boston, MA; Katya Ravid, Boston Univ Sch of Med, Boston, MA; Vipul C Chitalia, Boston Univ Medical Ctr, Boston, MA

5:45 PM

Q & A

5:50 PM

Regulators Of G Protein Signaling 10 And 18 Cooperate To Prevent Unnecessary Platelet Activation And Extend Normal Platelet Survival In The Circulation

**Daniel DeHelian** , Chelsea Thorsheim, Shuchi Gupta, Univ of Pennsylvania, Philadelphia, PA; Matthew Cooper, Thomas Jefferson Univ, Philadelphia, PA; Kelly Litts, Univ of Pennsylvania, Philadelphia, PA; Peisong Ma, Thomas Jefferson Univ, Cherry Hill, NJ; Lawrence Brass, Univ of Pennsylvania, Philadelphia, PA

5:55 PM

Q & A

# Moderated Digital Posters

## SI.MDP12 - New Frontiers in Cell Therapy

#### Moderated Posters 4, Science and Technology Hall

### Saturday, November 16, 2019, 5:10 PM - 6:00 PM

5:10 PM

Moderator

Paul Fedak, Calgary, AB, Canada

5:10 PM

Immortalization of Human Neonatal C-kit+ Cardiac Progenitor Cells Preserves Their Phenotype and Function at High Passage

**Emily L Ongstad** , AstraZeneca, Gaithersburg, MD; Rachana Mishra, Univ of Maryland, Baltimore, MD; Mehdi Belkhodja, AstraZeneca, Gaithersburg, MD; Sudhish Sharma, Univ of Maryland, Baltimore, MD; Ranjitha Gaddipati, Sandrina Phipps, AstraZeneca, Gaithersburg, MD; Sunjay Kaushal, Univ of Maryland Medical Cent, Baltimore, MD; Sotirios Karathanasis, AstraZeneca, Rockville, MD

5:15 PM

Q & A

5:20 PM

Single Cell Coating With Surface-Anchored Nanogel Improves the Engraftment and Reparative Potency of Transplanted Mesenchymal Stem Cells in Infarcted Rat Hearts

**Xin Yang Hu** , Ling Zhang, Jian'an Wang, Ben Wang, Zhejiang Univ, Hangzhou, China

5:25 PM

Q & A

5:30 PM

Tissue-engineered Pediatric Pulmonary Valve in Growing Lamb Model

Zeeshan Syedain, Mathew Lahti, **Robert Tranquillo** , Richard W Bianco, James M Berry, Sandra Johnson, Bee Haynie, Univ of Minnesota, Minneapolis, MN

5:35 PM

Q & A

5:40 PM

**The Influence of Scaffold Degradation Velocity on Quality of** In-Situ **Tissue Engineered Vascular Grafts. A Combined Magnetic Resonance Imaging and Histological Study**

**M. Uiterwijk** , B. F. Coolen, AmsterdamUMC, Amsterdam, Netherlands; S. Bofarid, J. Azzahhafi, Utrecht Univ, Utrecht, Netherlands; H. M. Janssen, S. H.M. Söntjens, SyMO-Chem, Eindhoven, Netherlands; W. Szymczyk, Eindhoven Univ of Technology, Eindhoven, Netherlands; A. C. van der Wal, AmsterdamUMC, Amsterdam, Netherlands; P. Y.W. Dankers, C. V.c. Bouten, Eindhoven Univ of Technology, Eindhoven, Netherlands; G. J. Strijkers, J. Kluin, AmsterdamUMC, Amsterdam, Netherlands

5:45 PM

Q & A

5:50 PM

Transplantation of an Antigenically-defined MSC Subpopulation Induces Superior Cardiac Repair After a Reperfused Myocardial Infarction

**Guangming Cheng** , Lin Zhao, Magdy Girgis, Univ of Nevada, Las Vegas, Las Vegas, NV; Arash Davani, Natl Endocrinological and Diabetes Inst, Ľubochňa, Slovakia; Yanjuan Yang, Jeryl Hauptman, Univ of Nevada, Las Vegas, Las Vegas, NV; Robert J Vincent, Univ of Kansas Medical Ctr, Kansas city, KS; Ewa K Zuba-Surma, Jagiellonian Univ, Krakow, Poland; Buddhadeb Dawn, Univ of Nevada, Las Vegas, Las Vegas, NV

5:55 PM

Q & A

# Moderated Digital Posters

## CM.MDP24 - Physiologic Effects of Therapeutic Agents in Diabetes

#### Moderated Posters 8, Science and Technology Hall

### Saturday, November 16, 2019, 5:10 PM - 6:00 PM

5:10 PM

Moderator

Darren K McGuire, Dallas, TX

5:10 PM

**Neuregulin-1 Promotes Cardiomyocyte Survival and Proliferation Under** in vitro **Conditions of Hypoxic Hyperglycemic Stress**

**Frederick Grady** , Lyndsay M Stapleton, Amanda N Steele, Stanford Univ, Palo Alto, CA; Hanjay Wang, Stanford Univ, Stanford, CA; Anahita Eskandari, Stanford Univ, Palo Alto, United States Minor Outlying Islands; Camille E Hironaka, Stanford Univ Sch of Medic, Palo Alto, CA; Akshara D Thakore, Kevin J. Jaatinen, Stanford Univ, Palo Alto, CA; Kiah M Williams, Stanford Univ, Stanford, CA; Rachel Blair, Stanford Univ, Palo Alto, CA; Y. Joseph Woo, Stanford Univ, Stanford, CA

5:15 PM

Q & A

5:20 PM

Epeleuton, A Novel Synthetic Second-Generation N-3 Fatty Acid, Decreased Triglycerides, Improved Glycemic Control and Decreased Markers of Inflammation in a Phase 2 Exploratory Study

**Moayed Hamza** , Markus Weissbach, David Coughlan, John Climax, Afimmune, Dublin, Ireland; Deepak L Bhatt, Brigham and Womens Hosp, Boston, MA

5:25 PM

Q & A

5:30 PM

Effect of Empagliflozin on Erythropoietin Levels and Red Blood Cell Morphology in Patients With Type 2 Diabetes and Coronary Artery Disease

**David Mazer** , Gregory MT Hare, St. Michael's Hosp, Univ of Toronto, Toronto, ON, Canada; Philip W Connelly, St Michael's Hosp, Toronto, ON, Canada; Fei Zuo, St. Michael's Hosp, Toronto, ON, Canada; Richard E Gilbert, St. Michael's Hosp, Univ of Toronto, Toronto, ON, Canada; Nadine Shehata, Mount Sinai Hosp, Univ of Toronto, Toronto, ON, Canada; Adrian Quan, St. Michael's Hosp, Toronto, ON, Canada; Hwee Teoh, St Michael's Hosp, Toronto, ON, Canada; Lawrence A Leiter, St. Michael's Hosp, Univ of Toronto, Toronto, ON, Canada; Bernard Zinman, Mount Sinai Hosp,Univ Toronto, Toronto, ON, Canada; Peter Juni, Kevin E Thorpe, St. Michael's Hosp, Univ of Toronto, Toronto, ON, Canada; Andrew T Yan, St Michael's Hosp, Univ of Toronto, Toronto, ON, Canada; Kim A Connelly, Subodh Verma, St Michael's Hosp, Toronto, ON, Canada

5:35 PM

Q & A

5:40 PM

Preventive Effect of Empagliflozin on Neointimal Hyperplasia After Drug Eluting Stent Implantation in Patients With Type2 Diabetes

**Takehiro Hashikata** , Stanford Univ, stanford, CA; Mikio Kishi, NTT Medical Ctr Tokyo, Tokyo, Japan; Masayasu Ikutomi, Stanford Univ, stanford, CA; Takahiro Jimba, Masashirou Matsushita, Akito Shindo, NTT Medical Ctr Tokyo, Tokyo, Japan; Susumu Katsushika, Tokyo Univ, Sch of Med, Tokyo, Japan; Takahiro Sato, Satoshi Ohnishi, Masao Yamasaki, NTT Medical Ctr Tokyo, Tokyo, Japan; Nobutaka Kakuda, Tokyo Univ, Sch of Med, tokyo, Japan

5:45 PM

Q & A

5:50 PM

Cardiovascular Outcomes With Glucagon-Like Peptide 1 Agonists and Sodium-Glucose Cotransporter 2 Inhibitors in Patients With Type 2 Diabetes: A Meta-Analysis

**Yeong-Min Lee** , Eun-Ji Park, Young-Ah Park, Jeong-Sook Seo, Han-Young Jin, Tae-Hyun Yang, Dae-Kyung Kim, Dong-Soo Kim, Jae-Sik Jang, Busan-Baik hospital, Busan, Korea, Republic of

5:55 PM

Q & A

# Moderated Digital Posters

## WS.MDP21 - Sex and Gender Influences on Patient and Provider Outcomes

#### Moderated Posters 7, Science and Technology Hall

### Saturday, November 16, 2019, 5:10 PM - 6:00 PM

5:10 PM

Moderator

Amparo C Villablanca, Davis, CA

5:10 PM

Developing a Veterans Affairs Women Atherosclerotic Cardiovascular Risk Assessment Model From Veterans Affairs National Electronic Health Records Data

**Haekyung Jeon-Slaughter** , UT Southwestern Medical Ctr, Dallas, TX; Xiaofei Chen, Southern Methodist Univ, Dallas, TX; Bala Ramanan, UT Southwestern Medical Ctr, Dallas, TX; Shirling Tsai, Univ Texas Southwstrn Med Ctr, Dallas, TX

5:15 PM

Q & A

5:20 PM

Posttraumatic Stress Disorder & Prevalence of Cardiovascular Risk Factors Among Women Veterans

**Ramin Ebrahimi** , UCLA, Los Angeles, CA; Jennifer Sumner, Columbia Univ Medical Ctr, New York, NY; Kristine Lynch, Univ of Utah, Salt lake city, UT; Benjamin Viernes, Gregorio Coronado, Univ of Utah, salt lake city, UT; Arya Naeim, Pacific Palisades Charter Highschool, Los Angeles, CA; Chi-Hong Tseng, UCLA, Los Angeles, CA; Paul Dennis, Jean Beckham, Duke Univ, Durham, NC

5:25 PM

Q & A

5:30 PM

Gender Differences in Medicare Payments Among Female and Male Cardiologists

**Inbar Raber** , Beth Israel Deaconess Medical Ctr, Boston, MA; Cian P. McCarthy, Massachusetts General Hosp, Boston, MA; Mahmoud S Al Rifai, Univ of Kansas, Wichita, KS; John W. McEvoy, Univ Coll Hosp Galway, Galway, Ireland

5:35 PM

Q & A

5:40 PM

Gender Disparities in Career Progression and Scholarly Productivity Persist in Academic Cardiothoracic Surgery

**Kiah M Williams** , Hanjay Wang, Simar Bajaj, Christian T O'Donnell, Mark Sanchez, Camille E Hironaka, Patpilai Kasinpila, Amelia C Watkins, Leah M Backhus, Jack H Boyd, Stanford Univ, Stanford, CA

5:45 PM

Q & A

5:50 PM

Sex Differences in Microcirculation Due to Repetitive Exposure to Bouts of Insufficient Nocturnal Sleep

**Huan Yang** , Beth Israel Deaconess Medical Ctr., Boston, MA; Monika Haack, Beth Israel Deaconess Medical Cente, Boston, MA; Vrushank Bhatt, Beth Israel Deaconess Medical Ctr., Boston, MA; Hans Meier-Ewert, Boston Medical Ctr, Boston, MA; Aristidis Veves, Beth Israel Deaconess Medical Ctr, Boston, MA; Janet Mullington, BIDMC & HMS, Boston, MA

5:55 PM

Q & A

# Abstract Oral Session

## EP.AOS.519 - Ancel Keys Memorial Lecture

#### 201C

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Veronique L Roger, Rochester, MN

5:30 PM

Ancel Keys Memorial Lecture

Aaron R Folsom, Minneapolis, MN

5:55 PM

Q&A

6:00 PM

Explaining Temporal Trends in Atrial Fibrillation Incidence Rates: A Community-Based Study Within an Integrated Health Care Delivery System

**Brent A Williams** , Geisinger Health System, Danville, PA; Alanna M Chamberlain, Mayo Clinic, Rochester, MN; James C Blankenship, Geisinger Medical Ctr, Danville, PA; Elaine Hylek, Boston Univ, Lexington, MA; Stephen Voyce, Geisinger Health System, Danville, PA

6:10 PM

Q & A

6:15 PM

Arterial Stiffness and Atrial Fibrillation Among Older Adults: The ARIC Cohort

**Zakaria Almuwaqqat** , J'Neka S Claxton, Emory Univ, Atlanta, GA; Jingkai Wei, Univ of North Carolina Sch of Public Health, Chapel Hill, NC; Lin Y Chen, Pamela L Lutsey, Faye L Norby, Univ of Minnesota, Minneapolis, MN; Elsayed Z Soliman, Wake Forest Sch of Med, Winston Salem, NC; Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD; Gerardo M Heiss, Univ North Carolina, Chapel Hill, NC; Alvaro Alonso, Emory Univ, Atlanta, GA

6:25 PM

Q & A

6:30 PM

Multi-Biomarker Prediction of Risk of Stroke in Atrial Fibrillation: The REasons for Geographic and Racial Differences in Stroke Study

**Matthew J Singleton** , Wake Forest Sch of Med, Winston-Salem, NC; Ya Yuan, Univ Alabama Birmingham, Vestavia, AL; Farah Z Dawood, Scripps Mercy Hosp, San Diego, CA; George Howard, Sch Public Health, Birmingham, AL; Suzanne E Judd, UAB, Birmingham, AL; Neil Zakai, Larner Coll of Med at the Univ of Vermont, Burlington, VT; Virginia J Howard, Univ of Alabama-Birmingh, Birmingham, AL; David M Herrington, Wake Forest Univ Sch Medici, Winston Salem, NC; Elsayed Z Soliman, Wake Forest Sch of Med, Winston Salem, NC; Mary Cushman, Univ of Vermont, Colchester, VT

6:40 PM

Q & A

# Abstract Oral Session

## GE.AOS.581 - Genomic and Precision Medicine Early Career Investigator Award Competition

#### 126A

### Saturday, November 16, 2019, 5:30 PM - 6:30 PM

5:30 PM

Moderator

Jennie Lin, Chicago, IL

5:30 PM

Moderator

D Kent K Arrell, Rochester, MN

5:30 PM

Epitranscriptomic Checkpoint of Immune Responses to Ischemic Disease

**Aikaterini Gatsiou** , Simon Tual-Chalot, Newcastle Univ, Newcastle upon Tyne, United Kingdom; Francesca Bonini, Inst of Cardiovascular Regener, Frankfurt am Main; Valeriana Cesarini, Ospedale Pediatrico Bambino Gesù IRCCS, Rome, Italy; Maurizio Martini, Fondazione Policlinico Univrio "A. Gemelli", Rome, Italy; Almudena Ortega-Gomez, LMU Munich, Munich, Germany; Dinesh K.A. Ramadurai, Univ of Utah Sch of Med, Salt Lake City, UT; Jedrzej Hoffmann, Univ Hosp Frankfurt, Frankfurt, Germany; Tommy Regen, Univ of Mainz, Mainz, Germany; Kerida Shook, Newcastle Univ, Newcastle upon Tyne, United Kingdom; Wei Chen, Southern Univ of Science and Technology, Guangdong, China; Stefan Guenther, Max-Planck Inst, Bad Neuheim, Germany; Domenico Alessandro Silvestris, Ospedale Pediatrico Bambino Gesù IRCCS, Rome, Italy; Shin Kwak, Univ of Tokyo, Tokyo, Japan; Craig Selzman, Utah Univ, Salt Lake City, UT; Ioakim Spyridopoulos, Newcastle Univ, Newcastle Upon Tyne, United Kingdom; Thomas Braun, Max-Planck Inst, Bad Neuheim, Germany; Ari Waisman, Univ of Mainz, Mainz, Germany; Stefanie Dimmeler, Inst for Cardiovascular Regeneration, Frankfurt Am Main, Germany; Angela Gallo, Ospedale Pediatrico Bambino Gesù IRCCS, Rome, Italy; Stavros G Drakos, Univ of Utah Sch of Med, Salt Lake Cty, UT; Oliver Soehnlein, LMU Munich, Munich; Konstantinos Stellos, Newcastle Univ, Newcastle Upon Tyne, United Kingdom

5:40 PM

Q & A

5:45 PM

Epigenetic Analyses of Human Left Atrial Tissue Identifies Gene Networks Underlying Atrial Fibrillation

**Amelia Weber Hall** , Broad Inst of MIT and Harvard, Cambridge, MA; Nathan R Tucker, Massachusetts General Hosp, Boston, MA; Mark Chaffin, Carolina Roselli, Broad Inst of MIT and Harvard, Cambridge, MA; Honghuang Lin, Boston Univ, Boston, MA; Valerio Bianchi, Univ Medical Ctr Utrecht, Utrecht, Netherlands; Geert Geeven, Univ Medical Ctr Utrecht, Utrecht, MA; Kenneth C Bedi, Kenneth Margulies, Univ of Pennsylvania, Philadelphia, PA; Wouter De Laat, Oncode Inst, Utrecht, Netherlands; Patrick T Ellinor, Massachsetts General Hosp, Boston, MA

5:55 PM

Q & A

6:00 PM

Transethnic Genome-wide Association Study Identifies 50 Loci Associated With Coronary Artery Disease and Improves Polygenic Risk Stratification and Mortality Prediction

**Satoshi Koyama** , Kaoru Ito, Chikashi Terao, Masato Akiyama, RIKEN Ctr for Integrative Medical Sciences, Yokohama, Japan; Hiroshi Matsunaga, Hirotaka Ieki, The Univ of Tokyo, Tokyo, Japan; Kouichi Ozaki, Yoshihiro Onouchi, RIKEN Ctr for Integrative Medical Sciences, Yokohama, Japan; Seitaro Nomura, Hiroshi Akazawa, The Univ of Tokyo, Tokyo, Japan; Momoko Horikoshi, Yukihide Momozawa, RIKEN Ctr for Integrative Medical Sciences, Yokohama, Japan; Koichi Matsuda, Yoshinori Murakami, The Univ of Tokyo, Tokyo, Japan; Michiaki Kubo, RIKEN, Yokohama, Japan; Hiroyuki Aburatani, The Univiersity of Tokyo, Tokyo, Japan; Yoichiro Kamatani, RIKEN Ctr for Integrative Medical Sciences, Yokohama, Japan; Issei Komuro, The Univ of Tokyo, Tokyo, Japan

6:10 PM

Q & A

6:15 PM

High-resolution Plasma Metabolomic Profiling to Predict Outcomes in Patients With Coronary Artery Disease

**Anurag Mehta** , Chang Liu, Aditi Nayak, Emory Univ Sch of Med, Atlanta, GA; Ayman Samman Tahhan, Yi-An Ko, Emory Univ, Atlanta, GA; Devinder Singh Dhindsa, Emory Univ Sch of Med, Poquoson, VA; Jeong Hwan Kim, Emory Univ, Atlanta, GA; Salim Hayek, Univ of Michigan, Ann Arbor, MI; Laurence Sperling, Puja K Mehta, Yan Sun, Karan Uppal, Emory Univ, Atlanta, GA; Dean Jones, Emory Univ Sch of Med, Atlanta, GA; Arshed A Quyyumi, Emory Univ, Atlanta, GA

6:25 PM

Q & A

# Abstract Oral Session

## CA.AOS.535 - Melvin L. Marcus Early Career Investigator Award in Cardiovascular Sciences Competition

#### 113BC

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Jianyi Zhang, Birmingham, AL

5:30 PM

Moderator

Anthony Rosenzweig, Boston, MA

5:30 PM

Dusp5 Triggers and Maintains Cell Cycle Block in Postnatal Cardiomyocytes

**Nikolay Bogush** , Lin Tan, hussain Naib, Emory Univ, Atlanta, GA; John W Calvert, Emory, Suwanee, GA; David Martin, Children's Hosp Oakland Res Inst, oakland, CA; Robert M Graham, Victor Chang Cardiac Res Inst., Sydney, Australia; Ahsan Husain, Nawazish Naqvi, Emory Univ, Atlanta, GA

5:40 PM

Q & A

5:45 PM

Myocardial G Protein-Coupled Receptor Kinase 5 Contributes to Impaired Cardiac Function and Immune Cell Recruitment in Ischemic Heart Failure

**Claudio De Lucia** , Lewis Katz Sch of Med, Temple Univ, Philadelphia, PA; Laurel A. Grisanti, Univ of Missouri, Columbia, MO; Giulia Borghetti, Michela Piedepalumbo, Jessica Ibetti, Lewis Katz Sch of Med, Temple Univ, Philadelphia, PA; Anna Maria Lucchese, Temple Univ, Philadelphia, PA; Eric W. Barr, Lewis Katz Sch of Med, Temple Univ, Philadelphia, PA; Erhe Gao, Lewis Katz Sch of Med at Temple Uni, Philadelphia, PA; Giuseppe Rengo, Univ of Naples Federico II, Naples, Italy; Steven R Houser, iMMEDIATE PAST President- AHA, Philadelphia, PA; Douglas G Tilley, Temple Univ, Philadelphia, PA; Walter J Koch, Temple Univ Sch Medic, Philadelphia, PA

5:55 PM

Q & A

6:00 PM

Inhibition of Autosis Attenuates Ischemia/Reperfusion Injury in the Heart

**Jihoon Nah** , Rutgers Univ NJMS, Newark, NJ; Peiyong Zhai, Rutgers Univ, Newark, NJ; Alvaro Fernandez, Univ of Texas Southwestern Medical Ctr, Dallas, TX; Satvik Mareedu, Rutgers Univ - NJMS, Newark, NJ; Beth Levine, Univ of Texas Southwestern Medical Ctr, Dallas, TX; Junichi Sadoshima, Rutgers New Jersey Medical Sch, Neweark, NJ

6:10 PM

Q & A

6:15 PM

Elevated O-Glcnacylation : An Independent Driver of Cardiomyopathy

**Priya Umapathi** , The Johns Hopkins Hosp, Baltimore, MD; Olurotimi Mesubi, Johns Hopkins Univ, Baltimore, MD; Partha Banerjee, The Johns Hopkins Univ Sch of Med, Baltimore, MD; Natasha Zachara, Johns Hopkins Univ Sch, Baltimore, MD; Qinchuan Wang, Johns Hopkins Univ, Balitmore, MD; Jonathan Granger, The Johns Hopkins Hosp, Baltimore, MD; Elizabeth Luczak, Johns Hopkins Univ, Baltimore, MD; Yuejin Wu, Univ of Iowa, Iowa City, IA; Liliana Florea, Conover Talbot, The Johns Hopkins Univ Sch of Med, Baltimore, MD; Gerald Warren Hart, Johns Hopkins Univ Sch Med, Baltimore, MD; Mark E Anderson, Johns Hopkins Univ, Baltimore, MD

6:25 PM

Q & A

6:30 PM

An Acute Immune Response Underlies the Benefit of Cardiac Adult Stem Cell Therapy

**Ronald J Vagnozzi** , Cincinnati Children's Hosp, Cincinnati, OH; Marjorie Maillet, Medpace, Cincinnati, OH; Michelle A Sargent, Hadi Khalil, Anne Katrine Johansen, Jennifer Schwanekamp, Allen York, Cincinnati Children's Hosp, Cincinnati, OH; Vincent Huang, Univ of Cincinnati, Cincinnati, OH; Matthias Nahrendorf, Massachusetts General Hosp and Harvard Medical Sch, Boston, MA; Sakthivel Sadayappan, Univ of Cincinnati, Cincinnati, OH; Jeff D Molkentin, Children's Hosp Medical Ctr, Cincinnati, OH

6:40 PM

Q & A

# Abstract Oral Session

## NR.AOS.369 - Shock and Awe: Living with an ICD

#### 118C

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Bunny J Pozehl, Omaha, NE

5:30 PM

Moderator

Lucinda J Graven, Tallahassee, FL

5:30 PM

Exercise Effects Heart Rate Variability After an Implantable Cardioverter Defibrillator

**Cynthia M. Dougherty** , Robert L. Burr, Univ Washington Sch Nursing, Seattle, WA

5:40 PM

Q & A

5:45 PM

Better Treatment Response for Patients Receiving an Initial ICD for Secondary Prevention in the Patient and Partner Randomized Trial

**Jonathan P Auld** , Elaine A Thompson, Cynthia M Dougherty, Univ of Washington, Seattle, WA

5:55 PM

Q & A

6:00 PM

Do No Harm: Defibrillator Knowledge, Gender, and Device-Related Concerns

**Jennifer L. Miller** , Univ of Kentucky, Frankfort, KY; Misook Lee Lee Chung, Univ of Kentucky Coll of Nur, Lexington, KY; Muna H Hammash, Univ of Louisville, Louisville, KY; Melanie Schrader, Univ of Louisville, Owensboro, KY; Debra K Moser, Univ of Kentucky, Lexington, KY

6:10 PM

Q & A

6:15 PM

Mechanisms to Improve Physical and Psychological Health Outcomes Following an Implantable Cardioverter Defibrillator (ICD)

**Ana Carolina Sauer Liberato** , Univ of Freiburg, Freiburg, Germany; Frances Elaine A Thompson, Univ of Washington, Seattle, WA; Cynthia M Dougherty, Univ Washington Sch Nursing, Seattle, WA

6:25 PM

Q & A

6:40 PM

Q & A

# Abstract Oral Session

## SA.AOS.498 - Vivien Thomas Early Career Investigator Competition

#### 109AB

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

J Daniel D Muehlschlegel, Boston, MA

5:30 PM

Moderator

Bradley G Leshnower, Atlanta, GA

5:30 PM

Diazoxide Preserves Myocardial Function in a Swine Model of Hypothermic Cardioplegic Arrest and Prolonged Global Ischemia

**Alejandro Suarez-Pierre** , Cecillia Lui, Xun Zhou, Sean Kearney, Melissa Jones, Jie Wang, Thomas S Metkus, Mary B Brady, Brian Cho, Jeffrey M Dodd-o, Jennifer S Lawton, Johns Hopkins Univ, Baltimore, MD

5:40 PM

Q & A

5:45 PM

A Novel Injury Site-Targeted Complement Inhibitor Reduces the Severity of Cardiac Allograft Vasculopathy

**Kunal J Patel** , Zhenxiao Tu, Changhai Li, Caroline Wallace, Carl Atkinson, Stephen Tomlinson, Medical Univ of South Carolina, Charleston, SC

5:55 PM

Q & A

6:00 PM

Nicorandil Pretreatment Induces Metabolic Tolerance to Spinal Cord Ischemia-Reperfusion Injury via ATP-Sensitive Potassium Channel Activation

**Yuki Ikeno** , Univ of Colorado, Aurora, CO; Christian Ghincea, Univ of Colorado, Denver, CO; Gavriel Roda, Linling Cheng, Univ of Colorado, Aurora, CO; Xianzhong Meng, Univ of Colorado Denver, Aurora, CO; Michael Weyant, Univ of Colorado, Aurora, CO; Joseph C Cleveland, UCD Cariothoracic Surgery, Aurora, CO; David A Fullerton, Muhammad Aftab, T. Brett Reece, Univ of Colorado, Aurora, CO

6:10 PM

Q & A

6:15 PM

Small Conductance Calcium-Activated Potassium Channels Activation Improves Myocardial Protection on Swine Cardiopulmonary Bypass and Cardioplegic Ischemia-Reperfusion Model

**Zhiqi Zhang** , Warren Alpert Medical Sch of Brown Univ, Rhode Island Hosp, Providence, RI; Afshin Ehsan, Rhode Island Hosp, Providence, RI; Neel Sodha, Warren Alpert Medical Sch of Brown Univ, Rhode Island Hosp, Providence, RI; Richard Clements, Providence VAMC, Providence, RI; Guangbin Shi, Rhode Island Hosp, Providence, RI; Ahmed Aboulgheit, Warren Alpert Sch of Med, Providence, RI; Martin A Kolodziejczak, Vasile Pavlov, Rhode Island Hosp, Providence, RI; Frank W Sellke, Brown Medical Sch, Providence, RI; Jun Feng, Rhode Island Hosp, Providence, RI

6:25 PM

Q & A

6:30 PM

**Comprehensive e** x vivo **Biomechanical Analysis of Five Clinically Utilized Operative Approaches to Reimplantation Aortic Valve-Sparing Root Replacement**

**Michael J Paulsen** , Annabel Imbrie-Moore, Hanjay Wang, Camille E Hironaka, Haley Lucian, Justin Farry, Akshara Thakore, Peter Chiu, Michael Ma, Y Joseph Woo, Stanford Univ, Stanford, CA

6:40 PM

Q & A

# Cardiovascular Seminar

## LF.CVS.570 - ApoB: Ready for Prime Time in Clinical Practice?

#### 201AB

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Donald M Lloyd-jones, Chicago, IL

5:30 PM

Atherogenic Lipid Particles

George Thanassoulis, Mont-royal, QC, Canada

5:38 PM

ApoB and LDL particles - Epidemiology and Role in Risk Assessment

John T Wilkins, Chicago, IL

5:55 PM

ApoB in the European Guidelines

Alberico L Catapano, Milano, Italy

6:03 PM

ApoB in the US Guidelines

Neil J Stone, Chciago, IL

6:11 PM

Barriers to adoption of ApoB in Practice

Ann Marie Navar, Durham, NC

6:19 PM

Lifelong Perspectives on ApoB

Allan D SNIDERMAN, Montreal, QC, Canada

6:27 PM

Panel Discussion

# Cardiovascular Seminar

## EA.CVS.53 - Atrial Fibrillation: Debates and Controversies

#### 108A

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Deborah Lockwood, Oklahoma City, OK

5:30 PM

Every AF Patient With Left Ventricular Dysfunction Should Undergo Catheter Ablation

Nassir Marrouche, salt lake city, UT

5:40 PM

Rebuttal

5:55 PM

Rebuttal

6:00 PM

CRT & AF: it Only Really Works if the AV Node is Ablated or Non-contributory

Matthew M Kalscheur, Madison, WI

6:10 PM

Rebuttal

6:15 PM

AF Patients Who Have Indication for CRT Do Not Have to Undergo AV Nodal Ablation

John Rickard, Cleveland Hts, OH

6:25 PM

Rebuttal

6:30 PM

Session Summary

# Cardiovascular Seminar

## QU.CVS.31 - Generic and Branded Drugs: What's in a Name?

#### 202AB

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Paul Poirier, Quebec City, QC, Canada

5:30 PM

Moderator

Kimberly S Newlin, Sacramento, CA

5:30 PM

Only the Cost Differs: Really?

Cynthia Jackevicius, Pomona, CA

5:45 PM

Generic versus Branded: Evidence From Observational Studies

Joshua Gagne, Boston, MA

6:00 PM

Generic versus Branded: Evidence From Randomized Trials

Dennis T Ko, Toronto, ON, Canada

6:15 PM

FDA's Work on Generic Drugs

Robert Lee Page II, Aurora, CO

6:30 PM

2019 Update on Contaminated Generics

Jacinthe Leclerc, Trois-Rivieres, QC, Canada

# Cardiovascular Seminar

## PH.CVS.523 - Latest in Management of RV Failure: Restore, Resuscitate or Replace?

#### 102AB

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Sofia Carolina Carolina Masri, Seattle, WA

5:30 PM

Moderator

Timothy Lahm, Indianapolis, IN

5:30 PM

Mechanisms and Medical Management of Chronic RV Failure

Harm J Bogaard, Amsterdam

5:41 PM

Monitoring RV Function and RV-PA Coupling via Non-invasive and Invasive Modalities

roberto badagliacca, Rome, Italy

5:52 PM

RV Reserve in PAH - Is it Relevant?

Ryan J Tedford, Charleston, SC

6:03 PM

Guided Atrial Septostomy, Pott's Shunt, Other Devices

Erika Rosenzweig, New York, NY

6:14 PM

Management of RV Failure in Critical Care Patients: Ventilator, Inotropic and Vasopressor Support

Jonathan Rich, Skokie, IL

6:25 PM

Right Ventricular and Biventricular Assist Devices and ECMO

Matthew Bacchetta, Amsterdam, Netherlands

6:36 PM

Discussion

# Cardiovascular Seminar

## CH.CVS.289 - Lost in Transition: ACHD Burden, Registries and Strategies to Improve Healthcare Utilization in Adolescents and Adults with Congenital Heart Disease

#### 111AB

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Arwa Saidi, Gainesville, FL

5:30 PM

Moderator

Peter Ermis, Houston, TX

5:30 PM

Understanding the Impact of Loss to FolLow Up in the CHD Population

Michelle Gurvitz, Boston, MA

5:45 PM

Creating a Transition Program: Models for Success

Keila N Lopez, Houston, TX

6:00 PM

Strength in Numbers: Understanding and Improving Long Term Outcomes in CHD Through Multicenter Networks and Collaboratives

Anitha John, Washington, DC

6:15 PM

Addressing Parent and Family Stress and Anxiety During the Transition Process

Adrienne Kovacs, Portland, OR

6:30 PM

Burden of ACHD Through the Lens of the Global Burden of Disease Study

Meghan Zimmerman, Washington, DC

# Cardiovascular Seminar

## HF.CVS.407 - PechaKucha Potpourri: The Key Things You Need to Know about Interesting Cardiomyopathies

#### Heart Theater

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Mark H Drazner, Dallas, TX

5:30 PM

Moderator

Sandra Chaparro

5:30 PM

Sarcoidosis

Richard K Cheng, Seattle, WA

5:37 PM

Q&A

5:40 PM

Chagas Disease

Andrea Z Beaton, Cincinnati, OH

5:47 PM

Q&A

5:50 PM

Check Point Inhibitors and Myocarditis

Javid Moslehi, Nashville, TN

5:57 PM

Q&A

6:00 PM

Hypertrophy Cardiomyopathy

Carolyn Ho, Boston, MA

6:07 PM

Q&A

6:10 PM

Stress Cardiomyopathy

Yasushi Sakata, Suita, Japan

6:17 PM

Q&A

6:20 PM

Recovered Cardiomyopathy

Jane E Wilcox, Chicago, IL

6:27 PM

Q&A

6:30 PM

Peripartum Cardiomyopathy

Uri Elkayam, Los Angeles, CA

6:37 PM

Q&A

6:40 PM

Discussion

# Cardiovascular Seminar

## VA.CVS.353 - Vasculo-Oncology: Evidence-Based Treatment in 2019

#### 103C

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Joerg Herrmann, Rochester, MN

5:30 PM

Moderator

Umberto Campia, Boston, MA

5:30 PM

Exploring the Cancer-Clot Link in the Venous System

Nigel Mackman, Chapel Hill, NC

5:45 PM

Risk of Arterial Thrombosis in Cancer Patients

Ana Barac, Washington, DC

6:00 PM

Cancer-Associated VTE: Selecting the Optimal Anticoagulant

Deborah Siegal, Hamilton, ON, Canada

6:15 PM

Atherosclerosis and Cancer - A CHIP off the Same block?

Paaladinesh Thavendiranathan, Toronto, ON, Canada

6:30 PM

Panel Discussion

# Cardiovascular Seminar

## CH.CVS.55 - World Cup of Pediatric Heart Failure: Great Debates with Audience Participation

#### 126B

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Yuk M Law, Seattle, WA

5:30 PM

Moderator

Betsy D Blume, MA

5:30 PM

Neonate With Biventricular Failure: VAD or Sedate, Medicate, +/- Trach to Transplant (VAD)

David L Sutcliffe, Dallas, TX

5:34 PM

Neonate With Biventricular Failure: VAD or Sedate, Medicate, +/- Trach to Transplant (Non VAD)

Borah Hong, Seattle, WA

5:38 PM

Discussion

5:42 PM

Genetic Panel Screening for Newly Diagnosed DCM/RCM/LVNC. Yay or Nay? (Yay)

Johanna Herkert, Groningen

5:46 PM

Genetic Panel Screening for Newly Diagnosed DCM/RCM/LVNC. Yay or Nay? (Nay)

Seema Mital, Toronto, ON, Canada

5:50 PM

Discussion

5:54 PM

Medication Therapy in Pediatric HCM: Treat Obstruction, Regardless of Symptoms

Michael McCulloch, Charlottesville, VA

5:58 PM

Medication Therapy in Pediatric HCM: for Symptoms Only

Mark W RUSSELL, Ann Arbor, MI

6:02 PM

Discussion

6:06 PM

Preemptive Cardiac Therapy in DMD with No Evidence of Cardiac Disease (asymptomatic, normal echo, no LGE): Treat or Not Treat? (Treat)

Christopher F Spurney, Washington, DC

6:10 PM

Preemptive Cardiac Therapy in DMD with No Evidence of Cardiac Disease (asymptomatic, normal echo, no LGE): Treat or Not Treat? (Not Treat)

Elizabeth M McNally, Chicago, IL

6:14 PM

Discussion

6:18 PM

Heart Failure Medication titration in Pediatric Dilated Cardiomyopathy: BNP is not needed

Heather T Henderson, Charleston, SC

6:22 PM

Heart Failure Medication Titration in Pediatric Dilated Cardiomyopathy: BNP Should Guide Therapy

Lindsay May, Salt Lake City, UT

6:26 PM

Discussion

6:30 PM

Manage This: Restrictive CM, NYHA Class I-II HF, Normal Pulmonary Artery Pressure, Normal Holter with No Palpitations or Syncope (List for Transplant)

Mariska Kemna, Seattle, WA

6:34 PM

Manage This: Restrictive CM, NYHA Class I-II HF, Normal Pulmonary Artery Pressure, Normal Holter with No Palpitations or Syncope (Don't List for Transplant)

Benjamin Mantell, New York, NY

6:38 PM

Discussion

# Early Career Events

## EC.02 - GPM Early Career Investigator Award Competition

#### Pennsylvania Convention Center, Room 121 C

### Saturday, November 16, 2019, 5:30 PM - 6:30 PM

This is not a CME/CE certified session

# Expert Theater

## ET.09 - AHA - One Brave Idea/Quest

#### Learning Studio 1, Booth # 5

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

This is not a CME/CE certified session

# Featured Science

## FS.AOS.05 - Early Phase Science

#### 103A

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Jeffrey S Berger, New York, NY

5:30 PM

Long-Term Safety and Efficacy of AG10 in Patients With Transthyretin Amyloid Cardiomyopathy (ATTR-CM): Interim Analysis of the Ongoing Phase 2 Open-Label Extension Study

**Daniel Judge** , Medical Univ of South Carolina, Charleston, SC; Stephen B Heitner, Oregon Health and Science U, Portland, OR; Rodney H Falk, Brigham and Women's Hosp, Boston, MA; Martha Grogan, Mayo Clinic, Rochester, MN; Daniel L Jacoby, Yale Sch of Med, New Haven, CT; Mathew S Maurer, New York Presbyterian Hosp, New York, NY; Van Nye Selby, UCSF, San Francisco, CA; Sanjiv J Shah, Northwestern Univ, Chicago, IL; Ronald Witteles, Stanford Univ Sch of Med, Stanford, CA; Leonid Katz, Satish Rao, Uma Sinha, Jonathan Fox, Eidos Therapeutics, San Francisco, CA

5:38 PM

Discussion

5:41 PM

A Randomised, Double-Blind, Dose Ranging Clinical Trial of Intravenous FDY-5301 in Acute STEMI Patients Undergoing Primary PCI: The CAMPFIRE (CArdiac Muscle Preservation Following Ischemia REperfusion) Study

David Adlam, Univ of Leicester, Leicester, United Kingdom; Neal Uren, Univ of Edinburgh, Edinburgh, United Kingdom; Keith Oldroyd, Golden Jubilee Hosp, Glasgow, United Kingdom; Shahzad Munir, New Cross Hosp, Wolverhampton West Midlands UK, United Kingdom; Andrew Sharp, Royal Devon and Exeter Hosp, Exeter, United Kingdom; Azfar Zaman, Newcastle Upon Tyne Hosp NHS Fndn Trust, Newcastle, United Kingdom; Hussain Contractor, Wythenshawe Hosp, Manchester, United Kingdom; Robert Kiss, Magyar Honvédség Egészségügyi Központ, Budapest, Hungary; Istvan Edes, Inst of Cardiology, Debrecen, Hungary; Maciej Zarebinski Jr., CSK WIM, Warsaw, Poland; Mario J Garcia, Montefiore Med Ctr, Bronx, NY; Piotr Musialek, Jagiellonian Univ,, Krakow, Poland; Janos Tomcsanyi, Budai Irgalmasrendi, Budapest, Hungary; Pawel Ptaszynski, Medical Univ Lodz, Lodz, Poland; Gergely Nagy, Univ of Debrecen, Miskolc, Hungary; Joanna Szachniewicz, Klinika Kardiologii, Worclaw, Poland; Lori Siegel, Faraday Pharmaceuticals Inc, Seattle, WA; Cheerag Shirodaria, Covance, Maidenhead, United Kingdom; Joseph B Selvanayagam, Flinders Medical Ctr,, Adelaide, Australia; Simon Tulloch, Faraday Pharmaceuticals, Inc, Seattle, WA; Campfire Investigators, Faraday Pharmaceuticals, Seattle, WA; **Keith M Channon** , Univ of Oxford, Oxford, United Kingdom

5:49 PM

Discussion

5:52 PM

Effect of SNF472 on Progression of Cardiovascular Calcification in Patients on Hemodialysis (Results of a Phase 2 Randomized Controlled Study: CaLIPSO)

**Paolo Raggi** , Univ of Alberta, Edmonton, AB, Canada; Antonio Bellasi, UOC Ricerca, Innovation and Brand Reputation Unit, Bergamo, Italy; Jordi Bover, Fundacio Puigvert, Hosp Santa Creu i Sant Pau, Barcelona, Spain; Mariano Rodriguez, Hosp Univrio Reina Sofia, Cordoba, Spain; Markus Ketteler, Klinikum Coburg GmbH, Coburg, Germany; Smeeta Sinha, Salford Royal NHS Fndn Trust, Salford, United Kingdom; Glenn Chertow, Stanford Univ Sch of Med, Palo Alto, CA; David Bushinsky, Univ of Rochester Sch of Med, Rochester, NY; Kristen Gillotti, Sanifit Therapeutics, S.A., San Diego, CA; Kevin Carroll, KJC Statistics, Cheshire, United Kingdom; Carolina Salcedo, Sanifit Therapeutics, S.A., Palma, Spain; Rekha Garg, Alex Gold, Sanifit Therapeutics, S.A., San Diego, CA; Joan Perelló, Sanifit Therapeutics, S.A., Palma, Spain

6:00 PM

Discussion

6:03 PM

Prospective, Single-Arm Clinical Investigation for the Non- Invasive Transthoracic Treatment of Subjects With Severe Symptomatic Aortic Valve Stenosis Using Valvosoft® Pulsed Cavitational Ultrasound Therapy (PCUT) - First-in-Man

**Emmanuel Messas** , Hop Européen Georges Pompidou, Paris, France; Alexander Ijsselmuiden, Selina Vlieger, Peter Den Heijer, Amphia Medical Ctr, Breda, Netherlands; Guillaume Goudot, INSERM PARCC, Paris, France; Etienne Puymirat, Hop Européen Georges Pompidou, Paris, France; Samuel Zarka, Bernard Choley, Hop Europeen Georges Pompidou, Paris, France; Christian Spaulding, Hop Europeen Geroges Pompidou, Paris, France; Albert A. Hagege, Hop Européen Georges Pompidou, Paris, France; Eloi Marijon, Hop Europeen Georges Pompidou, Paris, France; Mickael Tanter, INSERM ESPCI, Paris, France; Benjamin Bertrand, Mathieu C Remond, Cardiawave, Paris, France; Mathieu Pernot, INSERM ESPCI, Paris, France; Rene Spaargaren, Cardiawave, Paris, France

6:11 PM

Discussion

6:14 PM

First Human Study of a Novel Platelet Glycoprotein IIB/IIIA Inhibitor Designed for Point of Care ST-Segment Myocardial Infarction Treatment

**Dean J Kereiakes** , Timothy D Henry, The Christ Hosp, Cincinnati, OH; Anthony N DeMaria, UC San Diego Health, La Jolla, CA; Marilyn R Carlson, Precision for Med, Carlsbad, CA; Linda H Martin, Jeff Midkiff, The Christ Hosp, Cincinnati, OH; Mason LA Dixon, CirQuest Labs, LLC, Memphis, TN; Barry S Coller, Rockefeller Univ, New York, NY

6:22 PM

Discussion

6:25 PM

Field Implementation of Remote Ischemic Conditioning in ST-Elevation Myocardial Infarction: The FIRST Study

**Sheldon Cheskes** , Univ of Toronto, Toronto, ON, Canada; Maria Koh, ICES, Toronto, ON, Canada; Linda Turner, Sunnybrook Ctr for Prehospital M, Toronto, ON, Canada; Ronald Heslegrave, William Osler Health System, Brampton, ON, Canada; Richard Verbeek, Sunnybrook Ctr for Prehosptial Med, Toronto, ON, Canada; Paul Dorian, St Michael's Hosp, Toronto, ON, Canada; Damon Scales, Univ of Toronto, Toronto, ON, Canada; Bob Singh, Trillium Health Partners, Mississauga, ON, Canada; Shy Amlani, William Osler Health System, Brampton, ON, Canada; Madhu Natarajan, Mcmaster Univ, Hamilton, ON, Canada; Laurie J Morrison, Univ of Toronto, Toronto, ON, Canada; Priya Kakar, Peel Regional Paramedic Service, Brampton, ON, Canada; Roman Nowickyj, Region of Halton Paramedic Service, Oakville, ON, Canada; Michael Lawrence, Trillium Health Partners, Mississauga, ON, Canada; Jennifer Cameron, William Osler Health System, Brampton, ON, Canada; Dennis T Ko, ICES, Toronto, ON, Canada

6:33 PM

Discussion

6:36 PM

Intramyocardial Allogenic Mesenchymal Stem Cell Transplantation in Infants With Hypoplastic Left Heart Syndrome: Initial Results From the Phase I Trial

**Sunjay Kaushal** , Univ of Maryland Sch of Med, Baltimore, MD; Laxminarayana Korutla, Univ of Pennsylvania, Philadelphia, PA; Seth J Kligerman, Univ of California, San Diego, La Jolla, CA; Michael E Davis, Emory Univ Sch of Med, Atlanta, GA; Abigail M Snyder, Univ of Maryland Sch of Med, Baltimore, MD; S. Adil Husain, Univ Of Utah Health / Primary Children's Hosp, Salt Lake City, UT; Luca A Vricella, Univ of Chicago Med, Chicago, IL; Jessica R Hoffman, Emory Univ, Atlanta, GA; Manal T Al-Suqi, Univ of Maryland Sch of Med, Baltimore, MD; James S Tweddell, Cincinnati Childrens Hosp Medical Ctr, Cincinnati, OH; Ming-sing SI, Univ of Michigan, Ann Arbor, MI; William T Mahle, Children's Healthcare of Atlanta, Atlanta, GA; Barry R Davis, Univ of Texas Sch Pub Hlth, Houston, TX; Michael L. Terrin, Nicholas P Pietris, Univ of Maryland Sch of Med, Baltimore, MD; Prashanth Vallabhajosyula, Yale Univ, New Haven, CT; Sudhish Sharma, Univ of Maryland Sch of Med, Baltimore, MD; Rachana Mishra, Univ of Maryland, Baltimore, MD; Lasya Gaur, Johns Hopkins, Baltimore, MD; Narutoshi Hibino, Johns Hopkins Univ, Baltimore, MD; Anthony Oliva, Longeveron, Miami, FL; Shelby Kutty, Johns Hopkins Med, Baltimore, MD; Joshua M Hare, Univ of Miami, Miami, FL

6:43 PM

Discussion

# Frontiers in Science

## EA.FIS.604 - Arrhythmia Research Summit: Hottest New EP Advances and Connections 2019 with the Experts

#### 119AB

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Thomas F. Deering, Atlanta, GA

5:30 PM

Moderator

Ulrika Birgersdotter-green, La Jolla, CA

5:30 PM

Keynote: EP Highlights from 2019

Atul Verma, Newmarket, ON, Canada

5:40 PM

Q&A

5:42 PM

Keynote 2: Philadelphia Dreaming: A Legacy of Advancing EP into the Future

Francis E Marchlinski, Bala Cynwyd, PA

5:52 PM

Q&A

5:54 PM

High Impact Basic/Translational Advances in EP

David J Milan, Boston, MA

5:59 PM

Q&A

6:00 PM

Hottest New Technology in EP

Vivek Reddy, New York City, NY

6:05 PM

Q&A

6:06 PM

The Future of Electrophysiologic Mapping

Sanjiv M Narayan, Stanford, CA

6:11 PM

Q&A

6:12 PM

The Newest Concepts and Advances in Sudden Cardiac Arrest

Sumeet S Chugh, Los Angeles, CA

6:17 PM

Q&A

6:18 PM

Noninvasive Ventricular Arrhythmia Ablation

Phillip Cuculich, Saint Louis, MO

6:23 PM

Q&A

6:24 PM

Ablative Radiotherapy for Atrial Fibrillation

Paul Zei, Boston, MA

6:29 PM

Q&A

6:30 PM

Paradigm Changing Device Innovations

Ulrika Birgersdotter-green, La Jolla, CA

6:35 PM

Q&A

6:36 PM

Engineering of Electrical Conduction

Suraj Kapa, Rochester, MN

6:41 PM

Q&A

6:42 PM

Panel Discussion

# Frontiers in Science

## VA.FIS.346 - Frontiers in Science: Vascular Disease Summit: Clot Prevention and Clot Busting

#### 103B

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Peter Henke, ann arbor, MI

5:30 PM

Bioengineered Antithrombotic Targets

Michael A Holinstat, Ann Arbor, MI

5:45 PM

Anti-Selectins for Thrombosis Prevention

Thomas W Wakefield, Ann Arbor, MI

6:00 PM

Will Combining Antiplatelet and Fibrinolytic Mechanisms Work?

Mortimer Poncz, Philadelphia, PA

6:15 PM

Next Generation of Fibrinolytics

Sorin J BRENER, Brooklyn, NY

6:30 PM

Panel Discussion

Panel Panel Discussion, TX

# Hall

## EP.HT.03 - Hyde Park Talks - Controversies in EP

#### EP Central

### Saturday, November 16, 2019, 5:30 PM - 6:15 PM

5:30 PM

Moderator

Ann C Garlitski, Boston, MA

5:30 PM

Moderator

Jeffrey Olgin, San Francisco, CA

5:40 PM

Q&A

5:51 PM

Q&A

6:02 PM

Q&A

6:13 PM

Q&A

# Joint Sessions

## CS.JS.623 - Current Advances in International Issues: Joint Session with AHA and Chinese Society of Cardiology

#### 121A

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Xinliang Ma, Philadelphia, PA

5:40 PM

Q&A

5:45 PM

OCT Guided ACS Intervention Strategy

Jingbo Hou, Harbin, China

5:55 PM

Q&A

6:10 PM

Q&A

6:15 PM

The Global - Evolving - Face of Cardiovascular Diseases

Joseph A Hill, Dallas, TX

6:25 PM

Q&A

6:30 PM

Current Advances in International Issues

Steven R Houser, Philadelphia, PA

6:40 PM

Q&A

# Late-Breaking Science

## LBS.03 - Late Breaking Science III: Controversies in Contemporary Management of AS

#### Main Event II

### Saturday, November 16, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Jennifer S Lawton, Baltimore, MD

5:30 PM

Social Media Moderator

S Chris C Malaisrie, Chicago, IL

5:30 PM

Case Presentation: What Would You Do?

5:35 PM

Global Comparison of a Rivaroxaban-Based Antithrombotic Strategy versus an Antiplatelet-Based Strategy After Transcathether Aortic Valve Replacement to Optimize Clinical Outcomes (GALILEO) Trial: Primary Results

**George Dangas** , Mount Sinai Hosp, New York, NY; Jan G Tijssen, AMC - Univ of Amsterdam, Amsterdam, Netherlands; Roxana Mehran, ICAHN Sch of Med Mt. Sinai, New York, NY; Marco Valgimigli, Bern Univ Hosp, Bern; Pascal Vranckx, Hartcentrum Hasselt, Hasselt, Belgium; Robert C Welsh, Mazankowski Alberta Heart Inst, Edmonton, AB, Canada; Gennaro Giustino, Mount Sinai Hosp, New York City, NY; Karen Thomitzek, Mount Sinai Hosp, New York City, NY, Berlin; Peter Wildgoose, Janssen Pharmaceuticals, Titusville, NJ; Ronald Van Amsterdam, Cardialysis, Rotterdam, Netherlands; Stephan Windecker, Swiss Cardiovascular Ctr Bern, Bern

5:45 PM

Discussant

Elaine Hylek, BOSTON, MA

5:50 PM

Randomized Clinical Trial Comparing a Rivaroxaban-Based Strategy With an Antiplatelet-Based Strategy for the Prevention of Subclinical Leaflet Thrombosis in Transcatheter Aortic Valves (GALILEO-4D)

**Ole De Backer** , Rigshospitalet Univ Hosp, Copenhagen, Denmark; George Dangas, MT Sinai Medical Ctr, New York, NY; Hasan Jilaihawi, NYU Langone, New York City, NY; Jonathon Leipsic, UBC, Vancouver, BC, Canada; Christian Juhl Terkelsen, Aarhus Univ Hosp, Aarhus, Denmark; Raj Makkar, Cedar Sinai Medical Ctr, Los Angeles, CA; Annapoorna S Kini, Mount Sinai, New York City, NY; Karsten Tange Veien, Odense Univ Hosp, Odense, Denmark; Mohamed Abdel-Wahab, Heart Ctr, Segeberger Kliniken, Bad Segeberg; Won-Keun Kim, Kerckhoff Heart Ctr, Bad Nauheim, Germany; Prakash Balan, UT Physicians, Houston, TX; Nicolas Van Mieghem, Erasmus MC, Rotterdam, Netherlands; Ole Norling Mathiasen, Aarhus Univ Hosp, Aarhus, Denmark; Raban Jeger, Basel Univ Hosp, Basel, Switzerland; Martin Arnold, Erlangen Univ Hosp, Erlangen, Germany; Bjarne Nørgaard, Aarhus Univ Hosp, Aarhus, Denmark; Klaus Fuglsang Kofoed, Rigshospitalet Univ Hosp, Copenhagen, Denmark; Philipp Blanke, St. Paul's Hosp & UBC, Vancouver, BC, Canada; Stephan Windecker, Swiss Cardiovascular Ctr Bern, Bern; Lars Søndergaard, Rigshospitalet Univ Hosp, Copenhagen, Denmark

6:00 PM

Discussant

Victoria Delgado, Leiden, Netherlands

6:05 PM

Balloon-Expandable versus Self-Expandable TAVR on Paravalvular Regurgitation and 2-Year Mortality: A Propensity-Matched Comparison From the FRANCE-TAVI Registry

**Eric Van Belle** , Inst Coeur Poumon - CHU Lille, Lille, France; Flavien Vincent, CHU Lille, Lille, France; Julien Labreuche, Inst Coeur Poumon - CHU Lille, Lille, France; Vincent Auffret, CHU Rennes, Lille, France; Nicolas Debry, Inst Coeur Poumon - CHU Lille, Lille, France; Thierry Lefevre, ICPS Generale de Sante, Massy, France; Hélène Eltchaninoff, CHU Rouen, Lille, France; Martine Gilard, CHU Brest, Lille, France; Dominique Himbert, CHU Bichat, Paris, France; Jean-Philippe Collet, CHU Pitié Salpétrière, Paris, France; Teiger Emmanuel, CHU Henri Mondor, Lille, France; Alain Duhamel, CHU Lille, Lille, France; Emmanuel Robin, Augustin Coisne, Thomas Modine, Inst Coeur Poumon - CHU Lille, Lille, France; Guillaume Cayla, CHU Montpellier Nimes, Lille, France; Thibault Lhermusier, CHU Toulouse, Lille, France; Florence Leclercq, Arnaud de Villeneuve, Univ Hosp, Montpellier, France; Géraud Souteyrand, CHU Clermont Ferrand, Lille, France; Thomas Cuisset, CHU Marseille, Marseille, France; Christian Spaulding, European Hosp Georges Pompidou, Paris, France; Pascal Motreff, Univ Hosp Clermont, Clermont Ferrand, France; Thomas Gandet, Cardiac Surgery, Montpellier, France; Jean-Philippe Verhoye, Cardiac Surgery, Montpellier, France, Rennes Cedex; Bernard Lung, CHU Bichat, Paris, France; Olivier Darremont, Clinique Saint Augustin, Bordeaux, France; Nicolas Amabile, Inst Mutualiste Montsouris, Paris, France; Said Ghostine, Ctr Marie Lannelongue, Paris, France; Hervé Le Breton, CHU Rennes, Rennes, France; Cedric Delhaye, Inst Coeur Poumon - CHU Lille, Lille, France

6:15 PM

Discussant

Dharam Kumbhani, Dallas, TX

6:25 PM

Early Surgery versus Conventional Management for Asymptomatic Severe Aortic Stenosis

**Duk-Hyun Kang** , Asan Medical Ctr, Seoul, Korea, Republic of; Sung-Ji Park, Samsung Medical Ctr, Seoul, Korea, Republic of; Seung-Ah Lee, Sahmin Lee, Dae-Hee Kim, Asan Medical Ctr, Seoul, Korea, Republic of; Hyung-kwan Kim, Seoul Natl Univ Hosp, Seoul, Korea, Republic of; Sung-Cheol Yun, Asan Medical Ctr, Seoul, Korea, Republic of; Geu-Ru Hong, Yonsei Univ, Seoul; Jong-Min Song, Asan Medical Ctr, Seoul; Cheol-Hyun Chung, Jae-Kwan Song, Jae-Won Lee, Asan Medical Ctr, Seoul, Korea, Republic of; Seung Woo Park, Sungkyunkwan Univ. Sch of Med., Seoul

6:35 PM

Discussant

Robert O Bonow, Chicago, IL

6:40 PM

Case Revisited and Discussion

# Meet the Trialists

## CS.MT.02 - Meet the Trialists - COLCOT & BETonMACE Trials

#### Interventional Central

### Saturday, November 16, 2019, 5:30 PM - 6:15 PM

5:30 PM

Colcot

Jean-claude Tardif, Montreal, QC, Canada

5:30 PM

BETonMACE

Kausik K Ray, London, United Kingdom

# Unofficial Satellite Events

## USE.03 - Management of LDL-Cholesterol: Taking the Next Steps

#### Philadelphia Marriott Downtown, Liberty Ballroom A-B, 3rd Floor

### Saturday, November 16, 2019, 6:30 PM - 8:45 PM

6:30 PM

Programming

# Unofficial Satellite Events

## USE.04 - Interpreting and Applying Risk Assessment and Cardiovascular Outcomes Trial Data – Where Do We Go From Here?

#### Philadelphia Marriott Downtown, Salon ABC

### Saturday, November 16, 2019, 7:00 PM - 9:00 PM

7:00 PM

Programming

# Unofficial Satellite Events

## USE.05 - Navigating and Translating Guideline Directed Therapies and Interventions to Real-World Management of Cardiovascular Disease: A Case Based Analysis of Therapeutic Conundrums

#### Philadelphia Marriott Downtown

### Saturday, November 16, 2019, 7:00 PM - 9:00 PM

7:00 PM

Programming

# Unofficial Satellite Events

## USE.07 - Outcomes and Ongoing Challenges for the Patient with Complex Congenital Heart Disease

#### The Franklin Institute, Benjamin Franklin Hall

### Saturday, November 16, 2019, 7:00 PM - 10:30 PM

7:00 PM

Programming

# Unofficial Satellite Events

## USE.06 - Penn Medicine City of Brotherly Love Welcome Party

#### Loews Philadelphia Hotel

### Saturday, November 16, 2019, 7:30 PM - 11:00 PM

7:30 PM

Programming

# Council Sponsored Activities

## CSA.01 - 3CPR Council Reception & Annual Business Meeting

#### Philadelphia 201 hotel, room Horizons Rooftop Ballroom

### Saturday, November 16, 2019, 8:00 PM - 10:00 PM

This is not a CME/CE certified session

# Council Sponsored Activities

## CSA.03 - BCVS Council Annual Business Meeting and Awards Dinner

#### Philadelphia Marriott Downtown Hotel; room Salon G/H

### Saturday, November 16, 2019, 8:00 PM - 11:00 PM

This is not a CME/CE certified session

# Council Sponsored Activities

## CSA.05 - Clinical Cardiology Council Annual Business Meeting and Dinner

#### Philadelphia Marriott Downtown hotel, room Independence Ballroom 1/2/3

### Saturday, November 16, 2019, 8:00 PM - 11:00 PM

This is not a CME/CE certified session

# Council Sponsored Activities

## CSA.06 - CVRI Reception and Annual Business Meeting

#### Philadelphia Marriott Downtown Hotel, Room 309/310

### Saturday, November 16, 2019, 8:00 PM - 9:30 PM

This is not a CME/CE certified session

# Council Sponsored Activities

## CSA.07 - CVSA Council Annual Business Meeting and Awards Dinner

#### Philadelphia Marriott Downtown Hotel; room Salon L

### Saturday, November 16, 2019, 8:00 PM - 11:00 PM

This is not a CME/CE certified session

# Council Sponsored Activities

## CSA.08 - CVSN Awards Dinner and Annual Business Meeting

#### Philadelphia Marriott Downtown Hotel, Franklin 11/12

### Saturday, November 16, 2019, 8:00 PM - 11:00 PM

This is not a CME/CE certified session

# Council Sponsored Activities

## CSA.16 - GPM Annual Business Meeting and Reception

#### Philadelphia Marriott Downtown Hotel, Franklin 10

### Saturday, November 16, 2019, 8:00 PM - 9:30 PM

This is not a CME/CE certified session

# Council Sponsored Activities

## CSA.12 - Peripheral Vascular Disease Council Annual Reception and Dinner

#### Philadelphia Marriott Downtown Hotel, Franklin A

### Saturday, November 16, 2019, 8:00 PM - 10:00 PM

This is not a CME/CE certified session

# Council Sponsored Activities

## CSA.13 - QCOR Council Annual Reception

#### Philadelphia Marriott Downtown Hotel; room Franklin 8

### Saturday, November 16, 2019, 8:00 PM - 10:00 PM

This is not a CME/CE certified session

# Council Sponsored Activities

## CSA.14 - Young Hearts Council Reception & Annual Business Meeting

#### Philadelphia Marriott Downtown hotel, room Liberty Ballroom C

### Saturday, November 16, 2019, 8:00 PM - 10:00 PM

This is not a CME/CE certified session

# Unofficial Satellite Events

## USE.08 - Patient Driven Wearables and Home Medical Devices in CV Disease Management

#### Philadelphia Marriott Downtown , Ballroom Salon F on Level 5

### Sunday, November 17, 2019, 6:00 AM - 8:00 AM

6:00 AM

Programming

# Unofficial Satellite Events

## USE.02 - Reducing Cardiovascular Risks in Patients With Type 2 Diabetes: Identifying Your Role on the Diabetes Management Team

#### Philadelphia Marriott Downtown, Salons G,K-L

### Sunday, November 17, 2019, 6:00 AM - 8:00 AM

6:00 AM

Programming

# Unofficial Satellite Events

## USE.09 - PCSK9 Inhibitors in Perspective: Everything You Need to Know to Treat Lipids Today

#### Philadelphia Marriott Downtown, Salon E, 5th Floor

### Sunday, November 17, 2019, 7:00 AM - 8:00 AM

7:00 AM

Programming

# Abstract Oral Session

## EA.AOS.467 - Advances in Novel Ablation Technologies

#### 103B

### Sunday, November 17, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Ann C Garlitski, Boston, MA

7:15 AM

Preclinical Validation of a Device-Set of Impedance- and Magnetic Resonance Tracked Metallic Devices for Conventional and Mr-Guided Electrophysiological Intervention

**Akbar Alipour** , Johns Hopkins Medical Ctr, Baltimore, MD; Ehud J Schmidt, Johns Hopkins Medical Ctr Sch, Towson, MD; Aravindan Kolandaivelu, Johns Hopkins, Potomac, MD; Michael Guttman, Johns Hopkins Medical Ctr, Baltimore, MD; Jeffrey Schweitzer, 2Abbott Inc, Saint Paul, MN; Gregory Olson, 2Abbott Inc, Minnetonka, MN; Henry R Halperin, Johns Hopkins Medical Ctr, Baltimore, MD

7:25 AM

Q & A

7:30 AM

Stereotactic Radioablation for Atrial Fibrillation: A First in Man Series

**Pierre Qian** , Brigham and Women's Hosp, Boston, MA; Masaaki Shoji, Natl Cancer Ctr, Tokyo, Japan; Koichiro Kumagai, Fukuoka Univ Hosp, Fukuoka-shi, Japan; Jose Ramon Azpiri, H Christus Muguerza Alta Esp, Monterrey, Mexico; Jose Assad, Christus Hosp, Monterrey, Mexico; Jun Itami, Natl Cancer Ctr, Tokyo, Japan; Koji Inaba, Natl Cancer Ctr, Japan, Japan; Hiroyuki Okamoto, Abe Yoshihisa, Natl Cancer Ctr, Tokyo, Japan; Carlos Erick Cardona Ibarra, Cuauhtemoc de la Pena, Miguel Hinojosa, Christus Hosp, Monterrey, Mexico; Edward Gardener, Douglas Wong, Cyberheart Inc, Mountain View, CA; Alice B Jack, CyberHeart Inc, Portola Valley, CA; Thomas J Fogarty, Patrick Maguire, Cyberheart Inc, Mountain View, CA; Paul Zei, Brigham and Women's Hosp, Boston, MA

7:40 AM

Q & A

7:45 AM

Collateral Lung and Nerve Injury and Diaphragmatic Atrophy: Avoided by Pulsed Field Ablation

Mark T Stewart, Medtronic, Mounds View, MN; Nicole Kirchhof, Medtronic, Minnetonka, MN; Brian Howard, Medtronic PLC, Minneapolis, MN; Birce Onal, Medtronic PLC, Blaine, MN; David E Haines, William Beaumont Hosp, Royal Oak, MI; Atul Verma, Southlake Regional Health Ctr, Newmarket, ON, Canada; **Douglas L Packer** , Saint Marys Hosp, Rochester, MN

7:55 AM

Q & A

8:00 AM

Preventing Esophageal Injury Using a Novel Cardiac Mapping Device During Pulmonary Vein, Roof, and Posterior Wall Cryoablation for Atrial Fibrillation

Imran Niazi, Aurora Health, Milwaukee, WI; Lynn Erickson, **Ana Perez Moreno** , Xianmiao Qiu, Dhruv Chawla, Mohamed Djelmami-Hani, Aurora Sinai/St. Luke's Medical Ctrs, Univ of Wisconsin Sch of Med and Public Health, Milwaukee, WI

8:10 AM

Q & A

8:15 AM

Non-Invasive Radiation Therapy of Ventricular Tachycardia Storm Guided by Computerized 12-Lead ECG-Based Mapping

**Gordon Ho** , Todd Atwood, Kevin Murphy, Andrew Bruggeman, Elliot R McVeigh, Andrew Kahn, Gregory K Feld, Christopher Villongco, David E Krummen, Univ of California San Diego, La Jolla, CA

8:25 AM

Q & A

# Abstract Oral Session

## EP.AOS.572 - Contemporary Trends and Epidemiology of Heart Failure

#### 201C

### Sunday, November 17, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Ambarish Pandey, Dallas, TX

7:15 AM

Midlife Exposure to Cardiovascular Risk Factors and Future Development of Heart Failure Subtypes

**Laura P Cohen** , Columbia Univ Irving Medical Ctr, New York, NY; Eric Vittinghoff, Univ of California San Francisco, San Francisco, CA; Mark J Pletcher, UCSF, San Francisco, CA; Norrina B Allen, Sanjiv J Shah, John Wilkins, Northwestern Univ, Chicago, IL; Patricia Chang, Univ of North Carolina, Chapel Hill, NC; Chiadi Ericson Ndumele, Johns Hopkins Univ, Baltimore, MD; Anne B Newman, Univ Pittsburgh, Pittsburgh, PA; Diane G Ives, Univ Pittsburgh Epidemiology, Pittsburgh, PA; Mathew S Maurer, New York Presbyterian Hosp, New York, NY; Elizabeth Oelsner, Columbia Univ Irving Medical Ctr, New York, NY; Andrew E Moran, Columbia Univ, New York, NY; Yiyi Zhang, Columbia Univ Irving Medical Ctr, New York, NY

7:25 AM

Q & A

7:30 AM

Contemporary Patterns in Heart Failure Epidemiology Across Risk Factor Strata in Medicare Beneficiaries: 2011 to 2016

**Rohan Khera** , Lin Zhong, Univ of Texas Southwestern Medical Ctr, Dallas, TX; Joshua Parker, Univ of Texas Southwestern, Dallas, TX; Sandeep R Das, Univ of Texas Southwestern Med Ctr, Dallas, TX; Justin L Grodin, UT Southwestern, Dallas, TX; Jarett D Berry, UT Southwestern Medical Sch, Dallas, TX; Ambarish Pandey, UTSW Medical Ctr, Dallas, TX

7:40 AM

Q & A

7:45 AM

Longitudinal Trajectories of Albuminuria in Young Adulthood and Myocardial Structure and Function in Later Life: The Cardia Study

**Ravi B Patel** , Northwestern Univ Feinberg Sch of Med, Chicago, IL; Laura A Colangelo, Northwestern Univ, Chicago, IL; Jared P Reis, Natl Heart Lung Blood Inst, Bethesda, MD; Joao A Lima, Johns Hopkins Univ, Baltimore, MD; Sanjiv J Shah, Donald M Lloyd-Jones, Northwestern Univ, Chicago, IL

7:55 AM

Q & A

8:00 AM

Epidemiological Trends and Outcomes of Acute Myocarditis in the National Health Service of England

**Amrit S Lota** , Imperial Coll London, London, United Kingdom; Brian Halliday, Imperial Coll, London, London; Upasana Tayal, Royal Brompton Hosp, London; Sara Salmi, Royal Brompton Hosp, London, United Kingdom; Rameen Shakur, Univ of Cambridge, Cambridge, United Kingdom; Daniel Hammersley, Natl Heart and Lung Inst, London; Richard Jones, Imperial Coll London, London, United Kingdom; Piers Daubeney, Royal Brompton Hosp, London, United Kingdom; James Simon Ware, Imperial Coll London, London; John GF Cleland, Univ of Glasgow, Glasgow, United Kingdom; Stuart A Cook, Imperial Coll London, London, United Kingdom; Dudley J Pennell, Royal Brompton Hosp, London; Sanjay Kumar Prasad, Royal Brompton Hosp, London, United Kingdom

8:10 AM

Q & A

8:15 AM

Race and Sex Differences in Modifiable Risk Factors and Incident Heart Failure

**Danielle M. Kubicki** , Vanderbilt Univ Sch of Med, Nashville, TN; Meng Xu, Elvis A. Akwo, Debra Dixon, Daniel Munoz, William J. Blot, Thomas J Wang, Loren Lipworth, Deepak K. Gupta, Vanderbilt Univ Medical Ctr, Nashville, TN

8:25 AM

Q & A

# Cardiovascular Seminar

## HY.CVS.421 - Advances in Genetics and Pharmacogenetics of Hypertension

#### 108A

### Sunday, November 17, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

James M Luther, Nashville, TN

7:15 AM

Moderator

Anand Vaidya, Boston, MA

7:15 AM

Invited Presenter: New Genetic Diagnostics in Primary Aldosteronism

Kazutaka Namba, Kyoto, Japan

7:31 AM

Invited Presenter: Discovery of New Genetic Risk Factors for Hypertension in the Million Veterans Program

Adrianna Hung, Nashville, TN

7:47 AM

Invited Presenter: Beyond Primary Aldosteronism: subclinical aldosteronism in development of hypertension

Anand Vaidya, Boston, MA

8:03 AM

Invited Presenter: Pharmacogenomics of Hypertension; Current Status and Future Directions

Brian Rayner, Cape Town

8:19 AM

Discussion

# Cardiovascular Seminar

## AC.CVS.256 - Challenging Cardiovascular Paradigms in Cancer Patients: Do the Guidelines Apply?

#### 103A

### Sunday, November 17, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Carolina Masri, Seattle

7:15 AM

Moderator

Juan Plana, Houston, TX

7:15 AM

Cardiotoxicity in Cancer Patients: Beyond AnthracycLines

Edward Yeh, Houston, TX

7:30 AM

Management of Acute Coronary Syndrome in Patients With Active Cancer: How Do We Balance Risk of Thrombosis vs. Bleeding?

Carol L Chen, New York City, NY

7:45 AM

Aortic stenosis: Role of TAVR in Cancer Patients

Mauricio Cohen, Miami, FL

8:00 AM

Atrial Fibrillation in My Cancer Patient: Practical Anticoagulation Strategies

Daniel Addison, Columbus, OH

8:15 AM

Cardiogenic Shock in Cancer Patients: Is MCS a Viable Strategy?

Richard Cheng, Seattle, WA

# Cardiovascular Seminar

## AT.CVS.143 - How Basic Science Can Inform Clinical Decisions in the Management of Cardiovascular Calcification

#### 126A

### Sunday, November 17, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Dwight A Towler, Dallas, TX

7:15 AM

Moderator

Jane A Leopold, Boston, MA

7:15 AM

Genetic Influences on Cardiovascular Calcification

Cynthia St. Hilaire, Pittsburgh, PA

7:25 AM

Q&A

7:30 AM

Vascular Calcification of Aging

Catherine Shanahan, London, United Kingdom

7:40 AM

Q&A

7:45 AM

Clinical Implications of Cardiovascular Calcification

Linda L Demer, Los Angeles, CA

7:55 AM

Q&A

8:00 AM

Statins, PCSK9 and Coronary Calcium

Christie M Ballantyne, Houston, TX

8:10 AM

Q&A

8:15 AM

Inflammation and Coronary Calcification

Jane A Leopold, Boston, MA

8:25 AM

Q&A

# Cardiovascular Seminar

## EA.CVS.212 - Life in the Fast and Slow Lane: A Practical Approach to the Identification and Management of Acute Arrhythmias

#### 113A

### Sunday, November 17, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Janice Chyou, New York, NY

7:15 AM

Moderator

Graham Wong, Vancouver, BC, Canada

7:15 AM

Restless Nights - Arrhythmias in the Darkest Hours

Kenneth A Ellenbogen, Richmond, VA

7:27 AM

Q & A

7:30 AM

Making Sense of Tachycardia Alarms on Telemetry

Ratika Parkash, Halifax, NS, Canada

7:42 AM

Q & A

7:45 AM

Complex Atrial and Ventricular Arrhythmias

Jordan M Prutkin, Seattle, WA

7:57 AM

Q & A

8:00 AM

Arrhythmias Complicating Acute Ischemia

Ann C Garlitski, Boston, MA

8:12 AM

Q & A

8:15 AM

Advances in Risk Stratification of Hospitalized Patients and Off-site Central Telemetry Monitoring

Cara Pellegrini, San Francisco, CA

8:27 AM

Q & A

# Cardiovascular Seminar

## SA.CVS.345 - Perioperative Management of LVAD Patients and Case Discussion

#### 109AB

### Sunday, November 17, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Jacob Gutsche, Philadelphia, PA

7:15 AM

Moderator

Keki Balsara, TN

7:15 AM

Pace Yourself - Determining the Optimal initial LVAD Speed

Chun Choi, Baltimore, MD

7:26 AM

Taking a Chance- The Use of Prothrombin Complex Concentrates in Post-Implantation Hemorrhage

Vidya Rao, Stanford, CA

7:37 AM

A Bridge Too Far- Palliative Care After LVAD Implant

John MacArthur

7:48 AM

Preservation of Right Heart Function After LVAD

Sreekanth Cheruku, Dallas, TX

8:10 AM

Case Presentation: LVAD in the Postoperative Setting

Jacob RAPHAEL, Charlottesvle, VA

8:21 AM

Discussion

# Cardiovascular Seminar

## CH.CVS.209 - Running Up Hill: The Ups and Downs of Exercise Recommendations in Pediatric Cardiology

#### 111AB

### Sunday, November 17, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Jacob C Hartz, Boston, MA

7:15 AM

Moderator

Geetha Raghuveer, Kansas City, MO

7:15 AM

Physical Activity Recommendations: North America vs European

Patricia E. Longmuir, Ottawa, ON, Canada

7:30 AM

Physical Activity and Congenital Heart Disease

Paul Stephens, Philadelphia, PA

7:45 AM

Excercise Recommendations in Kawasaki Disease and Other Coronary Artery Anomalies

Jonathan Rhodes, Boston, MA

8:00 AM

Exercise Recommendations in Congenital Heart Disease

Arene Butto, Atlanta, GA

8:15 AM

Developing a Cardiac Rehabilitation Program

Naomi Gauthier, Boston, MA

# Council Sponsored Activities

## CSA.17 - Clinical Genomics Boot Camp

#### Pennsylvania Convention Center, Room 121 C

### Sunday, November 17, 2019, 7:15 AM - 9:15 AM

This is not a CME/CE certified session

# Joint Sessions

## EA.JS.1624 - Controversies in the Management of Patients with Atrial and Ventricular Arrhythmias: What Evidence Do We Have and What Research Is Still Needed?: Joint Session with AHA and Heart Rhythm Society

#### 121A

### Sunday, November 17, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Christine M Albert, Boston, MA

7:15 AM

Should Totally Subcutaneous Devices Be Considered Over Transvenous Systems for Patients with Cardiomyopathy and Reduced Ejection Fraction?

Andrea M Russo, Moorestown, NJ

7:45 AM

Considering Patient Preferences: Should Left Atrial Appendage Occlusion be Offered to Patients with Atrial Fibrillation Who Do Not Have Contraindications to Oral Anticoagulation?

Fred Kusumoto, Jacksonville, FL

7:55 AM

Screening for Atrial Fibrillation using Wearable Devices: Saving Lives or Potential for Unexpected Consequences?

Nassir F Marrouche, Salt Lake Cty, UT

8:05 AM

Case Presentation: Controversial Arrhythmia Management

JANET K. Han, Los Angeles, CA

8:10 AM

Panel Discussion

# Sunday Morning Program

## WS.SMP.80 - 10 Questions About Cardiovascular Disease in Women

#### Terrace Ballroom IV

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

Kathryn M Rexrode, Boston, MA

7:15 AM

Moderator

Laxmi Mehta, Columbus, OH

7:15 AM

Networking Session

8:00 AM

Which Management Strategy is Best for Women With MI?

Michelle O'Donoghue, Boston, MA

8:06 AM

Audience Discussion

8:11 AM

What Follow Up for CV Disease Prevention is Needed for Women With Pre-eclampsia?

Malamo Countouris, Pittsburgh, PA

8:17 AM

Audience Discussion

8:22 AM

What Type of Valve Replacement is Best for Women Contemplating Pregnancy?

Joanna Chikwe, New York, NY

8:28 AM

Audience Discussion

8:33 AM

What Testing Should I Do to Find Microvascular Disease?

Jennifer Lewey, Philadelphia, PA

8:39 AM

Audience Discussion

8:44 AM

How Can I Decide if Hormone Therapy is OK for My Patient?

Chrisandra Shufelt, Los Angeles, CA

8:50 AM

Audience Discussion

8:55 AM

What Makes Stable Ischemic Heart Disease Different in Women?

Harmony R Reynolds, New York, NY

9:01 AM

Audience Discussion

9:06 AM

How Should Primary Prevention Be Targeted to Women?

JoAnn E Manson, Boston, MA

9:12 AM

Audience Discussion

9:17 AM

How Should I Treat After Spontaneous Coronary Dissection?

Marysia Tweet, Rochester, MN

9:23 AM

Audience Discussion

9:28 AM

How Should Pregnant Women With MI Be Treated?

Nathaniel Smilowitz, New York, NY

9:34 AM

Audience Discussion

9:39 AM

What is the Risk After Takotsubo Syndrome?

Christian Templin, Zurich

9:45 AM

Audience Discussion

# Sunday Morning Program

## IN.SMP.375 - Best Interventional Trials of 2019

#### 107AB

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

Hani Jneid, Houston, TX

7:15 AM

Moderator

Ali E Denktas, Houston, TX

7:15 AM

Best Coronary Interventional Trials of 2019

Habib Samady, Atlanta, GA

7:55 AM

Discussion

8:10 AM

Break

8:25 AM

Best Structural Interventional Trials of 2019

alaide chieffo, Milan, Italy

9:05 AM

Discussion

9:20 AM

Best Peripheral Interventional Trials of 2019

Subhash Banerjee, Dallas, TX

10:00 AM

Discussion

# Sunday Morning Program

## CS.SMP.100 - Circulation: Innovation in Cardiovascular Science and Medicine

#### Nutter Theatre

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

James A de Lemos, Dallas, TX

7:15 AM

Moderator

Joseph A Hill, Dallas, TX

# Sunday Morning Program

## GE.SMP.336 - Clinical Genomics Boot Camp

#### 121C

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

Andrew P Landstrom, Durham, NC

7:15 AM

Moderator

Anwar A Chahal, Rochester, MN

7:15 AM

Panel Participant

Anjali Tiku Owens, Philadelphia, PA

7:15 AM

Panel Participant

Nosheen Reza, Philadelphia, PA

7:15 AM

Panel Participant

Pankaj Arora, Birmingham, AL

7:15 AM

Panel Participant

Allison Cirino, Boston, MA

7:15 AM

Panel Participant

Jordan Elizabeth Ezekian, Durham, NC

# Sunday Morning Program

## HF.SMP.348 - Great Debates in Heart Failure

#### 105AB

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

Jennifer T. THIBODEAU, Dallas, TX

7:15 AM

Moderator

David Markham, Atlanta, GA

7:15 AM

IV Diuretics Should Not Be Stopped When the Creatinine Rises in Decompensated HF

Jeffrey Testani, Guilford, CT

7:25 AM

IV Diuretics Should Be Stopped When the Creatinine Rises in Decompensated Heart Failure

Meredith A. A Brisco-Bacik, Philadelphia, PA

7:35 AM

Rebuttal: IV Diuretics Should Not Be Stopped When the Creatinine Rises in Decompensated HF

Jeffrey Testani, Guilford, CT

7:38 AM

Rebuttal: IV Diuretics Should Be Stopped When the Creatinine Rises in Decompensated Heart Failure

Meredith A. A Brisco-Bacik, Philadelphia, PA

7:41 AM

Vote

7:43 AM

Afib Ablation Should Be First Line Therapy in HFrEF

Mark S Link, Dallas, TX

7:53 AM

Afib Ablation Should Not Be First Line Therapy in HFrEF

Andrea Sarkozy, Edegem, Belgium

8:03 AM

Rebuttal: Afib Ablation Should Be First Line Therapy in HFrEF

Mark S Link, Dallas, TX

8:06 AM

Rebuttal: Afib Ablation Should Not Be First Line Therapy in HFrEF

Andrea Sarkozy, Edegem, Belgium

8:09 AM

Vote

8:11 AM

Percutaneous Mitral Valve Repair in HFrEF for Many!

Gregg Stone, New York, NY

8:21 AM

Percutaneous Mitral Valve Repair in HFrEF for Few!

Jean Obadia, Lyon, France

8:31 AM

Rebuttal: Percutaneous Mitral Valve Repair in HFrEF for Many!

Gregg Stone, New York, NY

8:34 AM

Rebuttal: Percutaneous Mitral Valve Repair in HFrEF for Few!

Jean Obadia, Lyon, France

8:37 AM

Vote

8:39 AM

Break

8:51 AM

Restrict Sodium in Many Patients With Heart Failure

Lynne Warner Stevenson, Nashville, TN

9:01 AM

Let Your Patients With Heart Failure Enjoy Their Pretzels! (Where's the Data to Stop Them?)

Javed Butler, Atlanta, GA

9:11 AM

Rebuttal: Restrict Sodium in Many Patients With Heart Failure

Lynne Warner Stevenson, Nashville, TN

9:14 AM

Rebuttal: Let Your Patients With Heart Failure Enjoy Their Pretzels! (Where's the Data to Stop Them?

Javed Butler, Jackson, MS

9:17 AM

Vote

9:19 AM

ARNI Before ACEi or ARB in New HFrEF: The Time is Now!

Akshay DESAI, Boston, MA

9:29 AM

ARNI Before ACEi or ARB in New HFrEF: Not Quite Yet!

Stephen S Gottlieb, Baltimore, MD

9:39 AM

Rebuttal: ARNI Before ACEi or ARB in New HFrEF: The Time is Now!

Akshay DESAI, Boston, MA

9:42 AM

Rebuttal: ARNI Before ACEi or ARB in New HFrEF: Not Quite Yet!

Stephen S Gottlieb, Baltimore, MD

9:45 AM

Vote

9:47 AM

Natriuretic Peptide Guided Therapy in HFrEF: Still a Viable Strategy

Michael Felker, Durham, NC

9:57 AM

Natriuretic Peptide Guided Therapy in HFrEF: No Longer a Viable Strategy

Anita Deswal, Houston, TX

10:07 AM

Rebuttal: Natriuretic Peptide Guided Therapy in HFrEF: Still a Viable Strategy

Michael Felker, Durham, NC

10:10 AM

Rebuttal: Natriuretic Peptide Guided Therapy in HFrEF: No Longer a Viable Strategy

Anita Deswal, Houston, TX

10:13 AM

Vote

# Sunday Morning Program

## CM.SMP.370 - Know Diabetes by Heart: A Stepwise Approach to Managing CVD in Your Patient With Diabetes

#### 204AB

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

Jorge Plutzky, Boston, MA

7:15 AM

Moderator

Jacquelyn Kulinski, Milwaukee, WI

7:15 AM

Choosing the Right Glucose-Lowering Medicne for the Right Patient

Joshua Joseph, Columbus, OH

7:35 AM

Managing Atherogenic Dyslipidemia: Treatment Beyond Statins

Anand Rohatgi, Dallas, TX

7:55 AM

The Ongoing Saga of Blood Pressure Control in Diabetes: How Low Should it Go?

Prakash C Deedwania, Fresno, CA

8:15 AM

Panel Discussion

8:30 AM

Break

9:00 AM

When is it Appropriate to Use Antiplatelet Therapy in Patients With Diabetes?

Louise Bowman, Oxford

9:20 AM

Effectively Implementing Lifestyle Interventions for Cardiometabolic Health and Disease

Paul Poirier, Quebec, QC, Canada

9:40 AM

How to Put it All Together: Early Identification and Appropriate Intervention

Sherita H Golden, Baltimore, MD

10:00 AM

Panel Discussion

# Sunday Morning Program

## MP.SMP.94 - Mitochondria as Mediators and Therapeutic Targets in Heart Failure

#### 120A

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

Anja Karlstaedt, Houston, TX

7:15 AM

Moderator

Lina Shehadeh, Miami, FL

7:15 AM

Moderator

Roberta A Gottlieb, Los Angeles, CA

7:15 AM

Therapeutic Targeting of Mitochondria

Elizabeth Murphy, Bethesda, MD

7:30 AM

Q&A

7:33 AM

OPA1 and Heart Failure

Evan Dale D Abel, Iowa City, IA

7:48 AM

Q&A

7:51 AM

Mitophagy in Cardiac Inflammation

Shuang Chen, Los Angeles, CA

8:06 AM

Q&A

8:09 AM

Autophagy and Cardioprotection

Abhinav Diwan, St Louis, MO

8:24 AM

Q&A

8:27 AM

Break

9:03 AM

GLP1Ra and Mitochondrial Turnover in the Heart

Allen M Andres, Los Angeles, CA

9:18 AM

Q&A

9:21 AM

Mitophagy in Diabetic Cardiomyopathy

Junichi Sadoshima, Neweark, NJ

9:36 AM

Q&A

9:39 AM

Mitochondrial Transplantation to the Heart

James D McCully, Boston, MA

9:54 AM

Q&A

9:57 AM

Glucose Metabolism in Heart Failure

Natasha Fillmore, Edmonton, AB, Canada

10:12 AM

Q&A

# Sunday Morning Program

## CE.SMP.111 - Mom, Where Do Baby Cardiac Myocytes Come From?

#### 120C

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

Hina Chaudhry, New York, NY

7:15 AM

Moderator

Sean M Wu, Stanford, CA

7:15 AM

The Combinatorial Power of Cell Cycle Factors in Cardiomyocyte ProLiferation

Tamer M a Mohamed, Louisville, KY

7:30 AM

Q&A

7:33 AM

Cyclin A2 Promotes Cardiomyocyte Proliferation

Hina W Chaudhry, New York, NY

7:48 AM

Q&A

7:51 AM

Cyclin D2 is Crucial Factor for Cardiomyocyte Regeneration

Loren J Field, Indianapolis, IN

8:06 AM

Q&A

8:09 AM

Transcription Factor Modulation of Cardiomyocyte Proliferation

Katherine E Yutzey, Cincinnati, OH

8:24 AM

Q&A

8:27 AM

Break

9:03 AM

Cytoskeleton Protein Modulation of Cardiomyocyte Regeneration

Eldad Tzahor, Rehovot, Israel

9:18 AM

Q&A

9:21 AM

Sca1 Lineage Tracing in the Adult Heart

Jop H Van Berlo, Minneapolis, MN

9:36 AM

Q&A

9:39 AM

Cardiac Lineage Development at the Single Cell Level

Fabienne Lescroart, France

9:54 AM

Q&A

9:57 AM

Why Does the Heart Lose the Ability to Regenerate After Birth

Enzo R Porrello, Brisbane, Australia

10:12 AM

Q&A

# Sunday Morning Program

## CE.SMP.40 - Novel Inflammation and Resolution Pathways in Heart Disease

#### 119AB

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

Pilar Alcaide, Boston, MA

7:15 AM

Moderator

Ganesh V Halade, Birmingham, AL

7:15 AM

Innate Cell DNA Sensing in Myocardial Injury

Dian J Cao, Dallas, TX

7:30 AM

Q&A

7:33 AM

Pathogenic T Regulatory Cells in the Heart

Shyam S Bansal, Columbus, OH

7:48 AM

Q&A

7:51 AM

Single Cell Sequencing to Understand Cardiovascular Inflammation

Kory J Lavine, St Louis, MO

8:06 AM

Q&A

8:09 AM

Gut Microbiome and Heart Failure

Wai Hong Wilson Tang, Cleveland, OH

8:24 AM

Q&A

8:27 AM

Break

9:03 AM

Humoral Immunity in Heart Disease

Khadija Rafiq, Philadelphia, PA

9:18 AM

Q&A

9:21 AM

DEndritic Cell Activation by Oxidative Strees in Cardiovascular Disease

Annet Kirabo, Nashville, TN

9:36 AM

Q&A

9:54 AM

Q&A

9:39 AM

Macrophage Efferocytosis in Cardiac Repair

Edward B Thorp, Chicago, IL

9:57 AM

Time to Resolve Inflammation

Michael S Conte, San Francisco, CA

10:12 AM

Q&A

# Sunday Morning Program

## CE.SMP.299 - Omics Approaches in Cardiovascular Medicine

#### 120B

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

Sarah Franklin, Salt Lake Cty, UT

7:15 AM

Moderator

Maggie Pui Yu Lam, Aurora, CO

7:15 AM

Omics, Big Data and Precision Medicne

Joseph C Wu, Stanford, CA

7:30 AM

Q&A

7:33 AM

N of 1 Study in Personal Omics

Victoria Parikh, Stanford, CA

7:48 AM

Q&A

7:51 AM

Cardiac Proteomics

Jennifer Van Eyk, Los Angeles, CA

8:06 AM

Q&A

8:09 AM

The Human Envirome

Aruni Bhatnagar, Louisville, KY

8:24 AM

Q&A

8:27 AM

Break

9:03 AM

Metabolomics

Robert E Gerszten, Boston, MA

9:18 AM

Q&A

9:21 AM

Systems Approaches to Cardiovascular Medicine

Joseph Loscalzo, Boston, MA

9:36 AM

Q&A

9:39 AM

Machine Learning Supported Data Analytics in Cardiovascular Medicine: Opportunities and Challenges

Peipei Ping, la, CA

9:54 AM

Q&A

9:57 AM

Epigenomics in Cardiac Development

Neil Chi, La Jolla, CA

10:12 AM

Q&A

# Sunday Morning Program

## PH.SMP.423 - Past Is Prologue: Recent, Ongoing and Future PAH Clinical Trials

#### 102AB

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

Paul B Yu, Boston, MA

7:15 AM

Moderator

Corey Ventetuolo, Providence, RI

7:15 AM

Lessons From the Walk-PHaSST Trial

Mark Gladwin, Pittsburgh, PA

7:25 AM

Lessons Learned From the IMPRES Trial

Werner Seeger, Giessen

7:35 AM

Lessons Learned From the ASA-STAT Trial

Steven M Kawut, New York, NY

7:45 AM

Lessons Learned From the TRANSFORM-UK Trial

Mark Toshner, Cambridge

7:55 AM

Lessons Learned From the DCA in PAH Trial

Evangelos D Michelakis, Edmonton, AB, Canada

8:05 AM

Lessons learned from ARROW: ASK1 inhibition in PAH

Stephan Rosenkranz, Cologne, Germany

8:15 AM

Moderated Debate

8:25 AM

Panel Participant

Hyung J Chun, New Haven, CT

8:25 AM

Discussion

8:40 AM

Break

8:55 AM

Investigation of Nitro Fatty Acid CXA-10 in Pulmonary Arterial Hypertension

Raymond Benza, Pittsburgh, PA

9:05 AM

Using SPECTrum of Innovative Endpoints to Examine Sotatercept

Janethe Pena, Brazil

9:15 AM

Ranolazine in Pulmonary Arterial Hypertension

Yuchi Han, Philadelphia, PA

9:25 AM

Safety and Efficacy of B-cell Depletion with Rituximab for the Treatment of Systemic Sclerosis-associated Pulmonary Arterial Hypertension

Roham Zamanian, Stanford, CA

9:35 AM

Investigations of Targeting Nrf2 and mTOR Signaling in PAH

Ronald J Oudiz, Manhattan Bch, CA

9:45 AM

Panel Discussion

# Sunday Morning Program

## CH.SMP.394 - Pay Me Now or Pay Me Later: Late Consequences of Early Decisions

#### 201AB

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

James S Tweddell, Cincinnati, OH

7:15 AM

Moderator

Anne Marie Valente, Boston, MA

7:15 AM

Panel Participant

Yuli Y Kim, Philadelphia, PA

7:15 AM

Panel Participant

Anne I Dipchand, Toronto, ON, Canada

7:15 AM

Panel Participant

Elizabeth A STEPHENSON, Toronto, ON, Canada

7:15 AM

Panel Participant

Katherine Economy, Boston, MA

7:15 AM

Panel Participant

Sitaram Emani, Boston, MA

7:15 AM

Panel Participant

Yoav Dori, Philadelphia, PA

7:15 AM

Panel Participant

Can Yerebakan, -, WA

7:15 AM

Panel Participant

Curt Daniels, Columbus, OH

7:15 AM

Invited Case Presenter Case 1: Ebstein. Presentation of a Child With Ebstein and TR - ASYMPTOMATIC. Decisions of Best Approach for Repair versus Conservative Management With a Focus on Long-term Outcomes

Jimmy C. Lu, Ann Arbor, MI

7:29 AM

Panel Discussion

7:42 AM

Invited Case Presenter 2: Child With L-loop TGA and WPW. Discussion of Timing of Interventions: Ablation, Double Switch or Do Nothing

Carolina A Escudero, Edmonton, AB, Canada

7:56 AM

Panel Discussion

8:09 AM

Invited Presenter: Case 3 Adolescent Girl Who Needs a Left-sided Heart Valve. Discussion for the Panel Will Focus on Choice of Heart Valve and Considerations for Future Interventions

Jennifer Nelson, Orlando, FL

8:23 AM

Panel Discussion

8:35 AM

Break

8:50 AM

Invited Case Presenter: Case 4: Choice of Homograft in a Patient Who Will Need a Transplant in the Future. Discussion Based on Tissue Typing and Appropriate Choices for Future Transplant Candidacy

Kirsten Rose-Felker, Pittsburgh, PA

9:04 AM

Panel Discussion

9:17 AM

Invited Presenter: Case 5. Adolescent With Fontan and PLE. Discussion Will Focus on Interventions - Lymphatics, Conversion, Transplant Considerations

Sairah Khan, Washington, DC

9:31 AM

Panel Discussion

9:44 AM

Invited Case Presenter Case 6: Arch Obstruction: Presentation of an Infant With Transverse Arch Hypoplasia. Decisions of Best Approach for Immediate and Long-term Optimal Outcomes

Tarek Alsaied, Cincinnati, OH

9:58 AM

Panel Discussion

# Sunday Morning Program

## PR.SMP.173 - Update in Clinical Lipidology

#### 204C

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

Francine K Welty, Brookline, MA

7:15 AM

Moderator

P. Barton Duell, Portland, OR

7:15 AM

Reducing Residual Cardiac Risk Through Reducing Inflammation

Abdulhamied Alfaddagh, Baltimore, MD

7:40 AM

Add-On to Statins in Secondary Prevention: EzetimiBe or Icosapent Ethyl?

Deepak L. Bhatt, Newton, MA

8:05 AM

Should We Target Triglycerides for ASCVD Risk Reduction

Boerge Nordestgaard, Copenhagen, Denmark

8:30 AM

Break

9:00 AM

Statin Thresholds in Primary Prevention

Ilana Richman, New Haven, CT

9:25 AM

Lp(a): In Whom to Measure and What to Screen for?

Wendy Post, Baltimore, MD

9:50 AM

Coronary Artery Calcium Screening: In Whom to Measure and Does it Help?

Michael Blaha, Baltimore, MD

# Sunday Morning Program

## IM.SMP.443 - Valvular Imaging: Aortic Valve/TAVR and Tricuspid Valve

#### 108B

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

Hector Deschle, Buenos Aires, Argentina

7:15 AM

Moderator

Brian Shapiro, Jacksonville, FL

7:15 AM

Quantification of Aortic Valvular Calcium: Impact on TAVR

Eric Williamson, Rochester, MN

7:26 AM

Using Cardiac CT for Guiding TAVR: What the Interventionist Should Know

Daniel Groves, CO

7:37 AM

Using Cardiac CT to Guide the TAVR Procedure: What the Interventionist Should Know (pArt 2)

Harold I Litt, Philadelphia, PA

7:48 AM

Intraoperative Echocardiography Imaging to Guide TAVR Placement

Konstantinos Koulogiannis, NJ

7:59 AM

Multimodality Imaging to Assess Procedural Complications

Victoria Delgado, Leiden

8:10 AM

Advanced Imaging to Guide Perivalvular Leak Closure

David Liang, Stanford, CA

8:16 AM

Panel Discussion

8:30 AM

Break

8:45 AM

Severe SecondaryTR After Left Side Surgery. What Do We Need to Know?

Robert Zilberszac, Vienna, Austria

9:06 AM

Severe TR in Special Situations: Congenital Diseases, Electronic Devices and Infective Endocarditis

Silva Makhoul, Buenos Aires, Argentina

9:21 AM

Follow Up of Severe TR. Echo, MRI, Both?

Mariano Falconi, Buenos Aires, Argentina

9:32 AM

Panel Discussion

# Sunday Morning Program

## QU.SMP.505 - What's New in the Guidelines: Updates and Controversies

#### 202AB

### Sunday, November 17, 2019, 7:15 AM - 10:15 AM

7:15 AM

Moderator

Steven M Bradley, Minneapolis, MN

7:15 AM

Moderator

Madeline R. Sterling, New York, NY

7:15 AM

2018 AHA/ACC GuideLine for the Management of Adults With Congenital Heart Disease

Karen Stout, Seattle, WA

7:35 AM

2018 ACC/AHA/HRS GuideLine on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay

Fred Kusumoto, Jacksonville, FL

7:55 AM

2018 AHA/ACC/HRS GuideLine for the Management of Patients With Atrial Fibrillation

Craig T. January

8:15 AM

Rhythm Management 2019: Guideline Gaps and Controversies

Jonathan P Piccini, Durham, NC

8:30 AM

Break

9:00 AM

2019 AHA/ACC Prevention GuideLines

Roger S BLUMENTHAL, Baltimore, MD

9:15 AM

2018 HHS Physical Activity GuideLines Advisory Committee Scientific Report

William E Kraus, Durham, NC

9:30 AM

2018 GuideLine on the Management of Blood Cholesterol

Neil J Stone, Winnetka, IL

9:45 AM

2017 AHA GuideLine for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults

Paul K Whelton, New Orleans, LA

10:00 AM

Prevention, Lipids, Hypertension: GuideLine Gaps and Controversies

Seth J Baum, Boca Raton, FL

# Cardiovascular Seminar

## NR.CVS.NS.607 - Cardiovascular Nursing Clinical Symposium

#### 118B

### Sunday, November 17, 2019, 8:00 AM - 5:15 PM

8:00 AM

Opening Remarks

Cynthia Dougherty, Seattle, WA

8:10 AM

Overview

8:15 AM

Moderator

Barbara Hinch, Chicago, IL

8:15 AM

Moderator

Mary Brennan, New York, NY

8:15 AM

A Case-Based Approach to the 2018 Multi-society Cholesterol Guideline

Lynne BRAUN, Chicago, IL

8:50 AM

Q&A

9:00 AM

Moderator

Anthony MCGUIRE, Standish, ME

9:00 AM

Moderator

Kimberley Ennis, Yonkers, NY

9:00 AM

What is this Electrocardiogram Telling Us? Interactive Case Discussions

Michele Pelter, San Francisco, CA

9:35 AM

Q&A

9:45 AM

Break

10:00 AM

Moderator

Barbara Leeper, Dallas, TX

10:00 AM

Moderator

Kathleen Fedyszen, Delray Beach, FL

10:00 AM

The Metabolic Heart: A Twisted Tail Between Heart Failure and Diabetes

Robert Page, Aurora, CO

10:35 AM

Q&A

10:45 AM

Moderator

Anthony MCGUIRE, Standish, ME

10:45 AM

Moderator

Connie White Williams, Hoover, AL

10:45 AM

Primary Prevention of CVD: Get the Guideline into Practice!

Cheryl DENNISON HIMMELFARB, Baltimore, MD

11:25 AM

Q & A

11:35 AM

Lunch

2:00 PM

Moderator

Heidi Salisbury, Half Moon Bay, CA

2:00 PM

Moderator

Barbara Leeper, Dallas, TX

2:00 PM

The Not-So-Forgotten Ventricle: Right Ventricular Failure

Susan Joseph, Dallas, TX

2:35 PM

Q&A

2:45 PM

Moderator

Bonnie YOUNG, Old Forge, PA

2:45 PM

His Bundle Pacing v Bi-V Pacing: What's the Difference and Who Benefits

Nancy Cash

3:20 PM

Q & A

3:30 PM

Break

3:45 PM

Moderator

Barbara Hinch, Chicago, IL

3:45 PM

Moderator

Kathleen Fedyszen, Delray Beach, FL

3:45 PM

Thrombectomy for Ischemic Stroke: Who, What, When, Where and Why

Sarah Livesay, Chicago, IL

4:20 PM

Q&A

4:30 PM

Moderator

Rose Shaffer, Bryn Mawr, PA

4:30 PM

Moderator

Mary Brennan, New York, NY

4:30 PM

Transcatheter Management of Multi-Valvular Disease

Rebecca Marcantuono, Philadelphia, PA

5:05 PM

Q & A

# Cardiovascular Seminar

## AT.CVS.390 - ATVB Journal Session: Adipose Tissue and Vascular (Dys)Function

#### 126A

### Sunday, November 17, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Ann Marie Schmidt, New York, NY

9:00 AM

Moderator

Janet Tinka Powell, London

9:00 AM

Adipose Tissue and Smooth Muscle Cell Cross-Talk

Eugene Chen, Ann Arbor, MI

9:10 AM

Q&A

9:12 AM

Adipose Tissue and Endothelial Cell Cross Talk

Kenneth Walsh, Charlottesville, VA

9:22 AM

Q&A

9:24 AM

Adipose Tissue and Vascular Perturbation/Atherosclerosis

Neal L Weintraub, Augusta, GA

9:34 AM

Q&A

9:36 AM

Adipose Tissue and Thrombosis

Matthew Flick

9:46 AM

Q&A

9:48 AM

Adipose Tissue and B Cells

Coleen A McNamara, Charlottesville, VA

9:58 AM

Q&A

10:05 AM

Q&A

# Cardiovascular Seminar

## CH.CVS.196 - First Annual Bongani Mayosi Memorial Lecture on Disparities in Global Cardiovascular Disease

#### 111AB

### Sunday, November 17, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Andrea Beaton, Cincinnati, OH

9:00 AM

Moderator

Raman K Kumar, Cochin, India

9:00 AM

Rheumatic Fever and Rheumatic Heart Disease – How Far Have We Have Come and Where Do We Need to Go?

Liesl Zühlke, Cape Town, South Africa

9:30 AM

Global Burden of Cardiovascular Disease

Greg Roth, Seattle, WA

9:40 AM

Access to Surgery and Catheterization for Cardiac Disease in Low- and Middle-Income Countries

Pranava Sinha, Washington, DC

9:50 AM

State of Support for Cardiovascular Research in Low- and Middle-Income Countries

George Mensah, Bethesda, MD

10:00 AM

Moderated Discussion

Andrea beaton, Washington, DC

# Cardiovascular Seminar

## EA.CVS.48 - New Insights into Stroke in Atrial Fibrillation

#### 113A

### Sunday, November 17, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Renate B Schnabel, Hamburg, Germany

9:00 AM

Moderator

Michael Ezekowitz, Villanova, PA

9:00 AM

Genetics-Based Prediction of Stroke in Atrial Fibrillation

Sudha Seshadri, San Antonio, TX

9:10 AM

Role of P Wave Indices in Improving Stroke Prediction in Atrial Fibrillation

Emelia J Benjamin, Brookline, MA

9:20 AM

How Predictive is the CHA2DS2-VASc Score for Ischemic Stroke in Non-White Populations?

Tze Fan Chao, Taipei, Taiwan

9:30 AM

Atrial Fibrillation and Stroke: Causal Relationship or Risk Marker?

Alan S Go, Oakland, CA

9:40 AM

Atrial Cardiomyopathy: Does the Risk Go Beyond the Arrhythmia?

Andreas Goette, Magdeburg, Germany

9:50 AM

Too Soon? When to Start Anti-Thrombotics After IntraCerebral Hemorrhage

Jennifer Ann Frontera, brooklyn, NY

10:00 AM

Q&A

# Cardiovascular Seminar

## AC.CVS.450 - Strategies to Reduce Risk in the Post MI Patient

#### 103A

### Sunday, November 17, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Vijay Nambi, Sugar Land, TX

9:00 AM

Moderator

Orly Vardeny, Minneapolis, MN

9:00 AM

Moderator

Faiez ZANNAD, VANDOEUVRE LES NANCY, France

9:00 AM

From ACE Inhibition to ARNI: The Quest to Reduce Adverse Ventricular Remodeling Post MI

Marc Pfeffer, Boston, MA

9:10 AM

Discussion

9:15 AM

Glycemic Strategies to Reduce Risk Following ACS in Diabetes: New Role for the Cardiologist

Darren K. K McGuire, Dallas, TX

9:25 AM

Discussion

9:30 AM

Optimal LDL Reduction in Secondary Prevention

Marc S Sabatine, Boston, MA

9:40 AM

Discussion

9:45 AM

Optimizing Utilization of Cardiac Rehabilitation Following Acute Myocardial Infarction

Todd M Brown, Birmingham, AL

9:55 AM

Discussion

10:00 AM

Interactive Panel Discussion

# Cardiovascular Seminar

## SA.CVS.576 - STS at AHA: Management of Challenging Clinical Scenarios: Intraoperative Tips and Tricks

#### 109AB

### Sunday, November 17, 2019, 9:00 AM - 10:25 AM

9:00 AM

Moderator

Michael P Fischbein, Stanford, CA

9:00 AM

Moderator

A Claire Claire Watkins, Stanford, CA

9:00 AM

Moderator

Wilson Y Szeto, Philadelphia, PA

9:00 AM

Management of Iatrogenic Aortic Dissection

Ibrahim Sultan, Pittsburgh, PA

9:12 AM

Porcelain Aorta: What to do during Cardiac Surgery

S Chris C Malaisrie, Chicago, IL

9:24 AM

Severe Mitral Annular Calcification: Options for Mitral Valve Replacement

Tom C Nguyen, Houston, TX

9:36 AM

Avoiding Patient Prosthetic Mismatch: How to do an Annular Enlargement Safely?

Joseph E Bavaria, Philadelphia, PA

9:48 AM

Intramyocardial Coronary Arteries: How to Always Locate During CABG

Piroze M Davierwala, Leipzig

10:00 AM

Biventricular Failure Post Cardiotomy: What are the options?

Pavan ATLURI, Philadelphia, PA

10:13 AM

Ventricular Rupture after Mitral Surgery

Y Joseph Y Woo, Stanford, CA

# Cardiovascular Seminar

## EA.CVS.106 - The Many Faces of Syncope - How to Manage a Complex Evaluation

#### 113BC

### Sunday, November 17, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Roopinder Sandhu, Edmonton, AB, Canada

9:00 AM

Moderator

Blair Grubb, Toledo, OH

9:00 AM

Key Differences Between USA and European Syncope GuideLines: Vive la Difference?

Brian Olshansky, Iowa City, IA

9:08 AM

Syncope/Collapse in the Extreme Elderly: Novel Approaches to Diagnosis

Andrea Ungar, florence, Italy

9:16 AM

Testing for Vasodepressor Susceptibility: Is it Needed in All forms of Reflex Syncope and How Reproducible is the Testing?

Denise Hachul, Brazil

9:24 AM

A Hard Impact - the Misdiagnosis of Syncope

Kimberly A Selzman, Salt Lake City, UT

9:32 AM

Neuro-humoral Changes in Vasovagal Syncope: Triggers or Bystanders?

Artur Fedorowski, Lund, Sweden

9:40 AM

Are Women More Susceptible to VVS Than Men. If So, Why?

Suzy Feigofsky, Carroll, IA

9:48 AM

Early Heart Rate and Blood Pressure Changes During Movement to Upright Posture: A Tool to Predict Autonomic Failure, Neurogenic Orthostatic Hypotensio,

Camille Frazier, Durham, NC

9:56 AM

Solitary Collapse Episode in Young Patients With Suspected Channelopathy: What's the Next Step?

Michael J Ackerman, Rochester, MN

10:04 AM

Q & A

# Early Career

## VA.EC.316 - Underrepresentation of Female Providers in Vascular Intervention: Opportunities and Challenges

#### 103B

### Sunday, November 17, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Marie D Gerhard-Herman, Boston, MA

9:00 AM

Moderator

Mark A Creager, Lebanon, NH

9:00 AM

Underrepresentation of Female Providers in Vascular Intervention: Challenges in Vascular Surgery

Amy Reed, Minneapolis, MN

9:15 AM

Underrepresentation of Female Providers in Vascular Intervention: Challenges in Vascular Research

Sonia Anand, Hamilton, ON, Canada

9:30 AM

Underrepresentation of Female Providers in Vascular Intervention: Challenges in Interventional Radiology

LeAnn Stokes, Nashville, TN

9:45 AM

Underrepresentation of Female Providers in Vascular Intervention: Challenges in Interventional Cardiology

Elissa Altin, New Haven, CT

10:00 AM

Panel Participant

Katherine Gallagher, Ann Arbor, MI

10:00 AM

Panel Participant

Constantino Pena, Miami, FL

10:00 AM

Panel Participant

Christina Fanola, Boston, MA

10:00 AM

Panel Discussion

# Featured Science

## FS.AOS.06 - Implementation Science Around the Globe

#### 112AB

### Sunday, November 17, 2019, 9:00 AM - 10:15 AM

9:00 AM

The Effect of Long-Term Exercise Training on Mortality and CVD-Events in Older Adults - The Generation 100 Study

**Dorthe Stensvold** , Hallgeir Viken, Jorunn Helbostad, Stian Lydersen, NTNU, Trondheim, Norway; Asbjørn Støylen, St.Olavs Hosp, Trondheim, Trondheim, Norway; Jan Erik Ingebrigtsen, NTNU, Trondheim, Norway; Sigmund Alfred Anderssen, The Norwegian Sch of Sport Sciences, Oslo, Norway; Maria Fiatarone Singh, The Univ of Sydney, Sydney, Australia; Håvard Dalen, St.Olavs Hosp, Trondheim, Trondheim, Norway; Jeff Coombes, Univ of Queensland, Brisbane, Australia; Sigurd Loe Steinshamn, St.Olavs Hosp, Trondheim, Trondheim, Norway; Øivind Rognmo, Ulrik Wisløff, NTNU, Trondheim, Norway

9:07 AM

Discussion

9:10 AM

A Cluster Randomized Trial of Cardiovascular Risk Reduction in Patients With Diabetes

Xiulin Shi, The First Affiliated Hosp of Xiamen Univ, Xiamen, China; **Jiang He** , Tulane Univ, New Orleans, LA; Mingzhu Lin, Changqin Liu, Yan Bing, Haiqu Song, Caihong Wang, Fangsen Xiao, Peiying Huang, Liying Wang, Yinxiang Huang, Mulin Zhang, The First Affiliated Hosp of Xiamen Univ, Xiamen, China; Chung-shiuan Chen, Katherine Obst, Tulane Univ, New Orleans, LA; Weihua Li, Shuyu Yang, Guanhua Yao, Xuejun Li, The First Affiliated Hosp of Xiamen Univ, Xiamen, China

9:16 AM

Discussion

9:19 AM

Use of a Genetic Risk Score to Predict Coronary and Vascular Events and Benefit From Evolocumab Therapy in Patients With Atherosclerotic Disease From the FOURIER Trial

**Nicholas A Marston** , Frederick K Kamanu, Francesco Nordio, Yared Gurmu, TIMI Study Group, Boston, MA; Carolina Roselli, Broad Inst, Cambridge, MA; Peter Sedgwick Sever, Imperial Coll London, London, United Kingdom; Terje Rolf Pedersen, Oslo Univ Hosp, Oslo, Norway; Anthony C Keech, NHMRC Clinical Trials Ctr, Camperdown Sydney, Australia; Huei Wang, AMGEN, Newbury Park, CA; Armando Lira Pineda, AMGEN, Thousand Oaks, CA; Robert Giugliano, TIMI Study Group, Boston, MA; Steven A Lubitz, Patrick T Ellinor, Massachusetts General Hosp, Boston, MA; Marc S Sabatine, Christian T Ruff, TIMI Study Group, Boston, MA

9:25 AM

Discussion

9:28 AM

Lowlands Saves Lives: A Randomized Controlled Trial to Compare CPR Quality and Long-Term Attitude Towards CPR Performance Between Face-to-Face and Virtual Reality Training With the Lifesaver VR-app

**Joris Nas** , Jos Thannhauser, Priya Vart, Robert-Jan van Geuns, Niels Van Royen, Judith Bonnes, Marc Brouwer, Radboudumc, Nijmegen, Netherlands

9:35 AM

Discussion

9:38 AM

Integrated Health Systems Strategies for Blood Pressure Reduction in Rural Communities in Bangladesh, Pakistan, and Sri Lanka - A Multi-Country Cluster Randomized Controlled Trial

**Tazeen H Jafar** , Duke-NUS Medical Sch, singapore, Singapore; Mihir Gandhi, Singapore Clinical Res Inst, Singapore, Singapore; Asita de Silva, Univ of Kelaniya, kelaniya, Sri Lanka; Imtiaz Jehan, Aga Khan Univ, Karachi, Pakistan; Aliya Naheed, Icddr.b, Dhaka, Bangladesh; Eric Finkelstein, Duke-NUS Medical Sch, Singapore, Singapore; Elizabeth Turner, Duke Global Health Inst, Durham, NC; Donald Morisky, UCLA, Los Angeles, CA; Shah Ebrahim, LSHTM, london, United Kingdom; Pryseley Assam, Singapore Clinical Res Inst, Singapore, Singapore; Feng Liang, Duke-NUS Medical Sch, Singapore, Singapore; COBRA-BPS Study Group

9:44 AM

Discussion

9:47 AM

Integrating Depression and Acute Coronary Syndrome Care in Low-Resource Hospitals in China (I-CARE Study): A Randomized Clinical Trial

**Yangfeng Wu** , Peking Univ Clinical Res Inst; The George Inst for Global Health at Peking Univ Health Science Ctr, Beijing, China; Xin Yu, Peking Univ Inst of Mental Health (Sixth Hosp), Natl Clinical Res Ctr for Mental Disorders (Peking Univ Sixth Hosp), Key Lab of Mental Health, Ministry of Health (Peking Univ), Beijing, China; Yidan Zhu, Peking Univ Clinical Res Inst, Beijing, China; Chuan Shi, Peking Univ Inst of Mental Health (Sixth Hosp), Natl Clinical Res Ctr for Mental Disorders (Peking Univ Sixth Hosp), Key Lab of Mental Health, Ministry of Health (Peking Univ), Beijing, China; Xian Li, The George Inst for Global Health at Peking Univ Health Science Ctr, Beijing, China; Ronghuan Jiang, Chinese PLA (People's Liberation Army) General Hosp, Chinese PLA (People's Liberation Army) Medical Sch, Beijing, China; Pei Gao, Sch of Public Health, Peking Univ, Beijing, China; Runlin Gao, Fuwai Hosp, Chinese Acad of Medical Sciences and Peking Union Medical Coll, Beijing, China; James Blumenthal, Duke Univ Medical Ctr, Durham, NC

9:56 AM

Patient Decision Support Through Electronic Behavioral Nudges: The Improvement in Medication Adherence Through the Implementation of Personalized Nudges (ENCOURAGE) Randomized Controlled Trial

**Benjamin D Horne** , Intermountain Medical Ctr; Stanford Univ Sch of Med, Salt Lake City, UT; Joseph B. Muhlestein, Donald L Lappe, Intermountain Medical Ctr; Univ of Utah, Salt Lake City, UT; Viet T Le, Heidi T May, Intermountain Medical Ctr, Salt Lake City, UT; Tami L Bair, Intermountain Medical Ctr, Salt Lake Cty, UT; Daniel Babcock, Daniel L. Bride, Intermountain Medical Ctr, Salt Lake City, UT; Kirk U. Knowlton, Intermountain Medical Ctr; Univ of California San Diego, Salt Lake City, UT; Jeffrey L. Anderson, Intermountain Medical Ctr; Univ of Utah, Salt Lake City, UT

10:02 AM

Discussion

10:05 AM

Effect of Different Lifestyle Interventions on Adults From Underserved Communities: The FAMILIA Trial

Rodrigo Fernandez-Jimenez, Risa Jaslow, Raquel Diaz-Munoz, Monali Fatterpekar, Maribel Santana, Andrea Clarke-Littman, Christopher Hill, Mohamed Al-Kazaz, Rajeev Samtani, Icahn Sch of Med at Mount Sinai, New York, NY; Emilia Bagiella, Icahn Sch of Med at Mount S, New York, NY; Zahi A Fayad, **Valentin Fuster** , Icahn Sch of Med at Mount Sinai, New York, NY; FAMILIA Investigators

10:11 AM

Discussion

# FIT Event

## FIT.13 - Cardiac Critical Care: What, How, and Why

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Sunday, November 17, 2019, 9:00 AM - 9:45 AM

This is not a CME/CE certified session

# Joint Sessions

## CS.JS.624 - Atrial Fibrillation Management: From Basic Research to Clinical: Joint Session with AHA and Great Wall International Congress of Cardiology

#### 121A

### Sunday, November 17, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Chang-Sheng Ma, Beijing, China

9:12 AM

Q&A

9:17 AM

Genomic Basis and Molecular Mechanism of Atrial Fibrillation

Qing Kenneth Wang, Cleveland, OH

9:29 AM

Q&A

9:34 AM

Challenges in Anticoagulation and Stroke Prevention for AF

Manesh R Patel, Durham, NC

9:46 AM

Q&A

9:51 AM

Approaches to Catheter Ablation of Nonparoxysmal Atrial Fibrillation

Bing Yang, China

10:03 AM

Q&A

# Late-Breaking Science

## LBS.04 - Late Breaking Science IV: State of the Art Interventional Management for ACS Patients

#### Main Event I

### Sunday, November 17, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Jacqueline E Tamis-Holland, New York, NY

9:00 AM

Moderator

Jinnette Dawn Abbott, Providence, RI

9:00 AM

Social Media Moderator

Sunil V Rao, Durham, NC

9:00 AM

Ticagrelor With Aspirin or Alone in High-Risk Patients After Coronary Intervention for Acute Coronary Syndrome

**Usman Baber** , Icahn Sch of Med at Mount Sinai, New York, NY; George Dangas, Mt Sinai Medical Ctr, New York, NY; Samin K. Sharma, Mount Sinai Hosp, New York, NY; Dominick Joseph Angiolillo, Univ of Florida, Jacksonville, FL; Carlo Briguori, Mediterranea Cardiocentro, Naples, Italy; David J Cohen, Univ of Missouri-Kansas City, Kansas City, MO; Timothy Collier, London Sch of Hygiene & Tropical Med, London, United Kingdom; Dariusz Dudek, Jagiellonian Univ, Cracow, Poland; Vladimir Dzavik, Univ Health Network, Toronto, ON, Canada; Javier Escaned, Hosp Clinico San Carlos, Madrid, Spain; Robert Gil, Klinika Kardiologii, Warsaw, Poland; Paul A Gurbel, Inova Heart and Vascular, Lutherville, MD; Christian W Hamm, Kerckhoff Heart Ctr, Bad Nauheim, Germany; Timothy D Henry II, The Christ Hosp, Cincinnati, OH; Kurt Huber Jr., Wilhelimne Hosp, Vienna, Austria; Adnan Kastrati, Deutsches Herzzentrum, Munich; Upendra Kaul, Fortis Escorts Heart Inst, New Delhi, New Delhi, DE; Ran Kornowski, Rabin Medical Ctr, Israel, Petach Tikva, Israel; Mitchell W Krucoff, Duke Medical Ctr, Chapel Hill, NC; Vijay Kunadian, Newcastle Univ, Newcastle upon Tyne, United Kingdom; Steven Marx, Columbia Unversity, New York, NY; Shamir R. Mehta, HHS General Site, Hamilton, On, ON, Canada; David J Moliterno, Univ of Kentucky, Lexington, KY; E Magnus Ohman, Duke Univ Med Ctr, Durham, NC; Keith Oldroyd, Duke Univ Med Ctr, Durham, NC, Glasgow, United Kingdom; Gennaro Sardella, Dept.of Cardiovascular Sciences,Policlinico Umbert, Rome, Italy; Samantha Sartori, Icahn Sch of Med, New York, NY; Richard Shlofmitz, St Francis Hosp, Roslyn, NY; Philippe Gabriel Steg, Hop Bichat, Paris, France; Giora Weisz, Shaare Zedek Medical Ctr, Jerusalem, Israel; Bernhard Witzenbichler, Charite Campus Benjamin Franklin, Berlin, Germany; Han Yaling, Chinese Society of Cardiology, Shenyang, China; Stuart Pocock, London Sch of Hygiene and Tropic, London; C M Gibson, Beth Israel Deaconess Med Ctr, Boston, MA; Roxana Mehran, Icahn Sch of Med Mt Sinai, New York, NY

9:09 AM

Discussant

Michelle L Odonoghue, Boston, MA

9:13 AM

Colchicine in Percutaneous Coronary Intervention

**Binita Shah** , VA NY Harbor Healthcare System, NYU Sch of Med, New York, NY; Michael Pillinger, NYU Sch of Med, New York, NY; Hua Zhong, NYU Sch of Med, NYC, NY; Nicole Ratnapala, Bruce Cronstein, NYU Sch of Med, New York, NY; Jeffrey Lorin, Manhattan VA Hosp, New York, NY; Frederick Feit, Nathaniel Smilowitz, Fatmira Curovic, NYU Sch of Med, New York, NY; Leandro C. Maranan, Manhattan VA Hosp, New York, NY; Stuart D Katz, NYU Sch of Med, New York, NY

9:22 AM

Discussant

Subodh Verma, Toronto, ON, Canada

9:26 AM

Non-Culprit Lesion Plaque Morphology in Patients With ST-Segment Elevation Myocardial Infarction: Results From the COMPLETE Trial Optical Coherence Tomography (OCT) Substudy

**Natalia Pinilla Echeverri** , Shamir R. Mehta, McMaster Univ, Hamilton, ON, Canada; Jia Wang, Population Health Res Inst, Hamilton, ON, Canada; Shahar Lavi, Univ Western Ontario, London, ON, Canada; David Alexander Wood, Univ of British Columbia, Vancover, BC, Canada; Warren Cantor, Southlake Regional Health Ctr, Newmarket, ON, Canada; Kevin R Bainey, Univ of Alberta, Edmonton, AB, Canada; Salem Kassam, Rouge Valley Centenary Health Ctr, Toronto, ON, Canada; Erick Schampaert, Hosp Sacre Coeur De Montreal, Montreal, QC, Canada; Roxana Mehran, Icahn Sch of Med Mt Sinai, New York, NY; Robert F Storey, Univ Sheffield Medical Sch, Sheffield, Ukraine; Helen Nguyen, Brandi Meeks, Population Health Res Inst, Hamilton, ON, Canada; John A Cairns, Univ British Columbia, Vancouver, BC, Canada; Tej Sheth, McMaster Univ, Hamilton, ON, Canada

9:35 AM

Discussant

Frans J Van De werf, Leuven, Belgium

9:39 AM

One Year Outcomes of Coronary Angiography After Cardiac Arrest

**Jorrit Lemkes** , Gladys Janssens, Amsterdam Univ Medical Ctr, Amsterdam, Netherlands; Nina van der Hoeven, Amsterdam; Lucia Jewbali, Eric Dubois, Erasmus MC, Rotterdam, Netherlands; Martijn Meuwissen, Tom Rijpstra, Amphia Hosp, Breda, Netherlands; Hans Bosker, Michiel Blans, Rijnstate Hosp, Arnhem, Netherlands; Gabe Bleeker, Rémon Baak, Haga Hosp, Den Haag, Netherlands; Georgios Vlachojannis, Den Haag, MA; Bob Eikemans, Maasstad Hosp, Rotterdam, Netherlands; Pim van der Harst, Iwan van der Horst, UMCG, Groningen, Netherlands; Michiel Voskuil, Joris van der Heijden, UMCU, Utrecht, Netherlands; Albertus Beishuizen, Martin Stoel, Medisch Spectrum Twente, Enschede, Netherlands; Cyril Camaro, Hans van der Hoeven, Radboud Univ Medical Ctr, Nijmegen, Netherlands; José Henriques, Alexander Vlaar, Amsterdam Univ Medical Ctr, Amsterdam, Netherlands; Maarten Vink, OLVG hospital, Amsterdam, Netherlands; Ton Heestermans, Noordwest Ziekenhuisgroep, Alkmaar, Netherlands; Thijs Delnoij, Maastricht Univ Medical Ctr, Maastricht, Netherlands; Gillian Jessurun, Scheper Hosp, Emmen, Netherlands; Pranobe Oemrawsingh, MCH Westeinde, The Hague, Netherlands; Marcel Gosselink, Isala Hosp, Zwolle, Netherlands; Koos Plomp, Tergooi Hosp, Blaricum, Netherlands; Michael Magro, Elisabeth-Tweesteden Hosp, Tilburg, Netherlands; Paul Elbers, Peter van de Ven, Heleen Oudemans-van Straaten, Niels van Royen, Amsterdam Univ Medical Ctr, Amsterdam, Netherlands

9:48 AM

Discussant

Joaquin Emeterio Cigarroa, Portland, OR

9:52 AM

Mortality and Bleeding Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock Undergoing Percutaneous Coronary Intervention With Impella® vs Intra-Aortic Balloon Pump

**Sanket Dhruva** , UCSF Sch of Med, San Francisco, CA; Joseph S Ross, Yale Univ, New Haven, CT; Bobak Mortazavi, Texas AM Univ, College Sta, TX; Nate Hurley, Texas A&M Coll of Med, College Station, TX; Harlan M Krumholz, Jeptha P Curtis, Yale Univ, New Haven, CT; Alyssa Berkowitz, Yale-New Haven Hosp Ctr for Outcomes Res and Evaluation, New Haven, CT; Frederick A Masoudi, Univ of Colorado AMC, Aurora, CO; John Messenger, Univ of Colorado SOM, Aurora, CO; Craig Parzynski, Yale-New Haven Hosp Ctr for Outcomes Res and Evaluation, New Haven, CT; Che Ngufor, Mayo Clinic, Rochester, MN; Saket Girotra, Univ Iowa, Iowa City, IA; Amit P Amin, Washington Univ Cardiology, Saint Louis, MO; Nilay Shah, Mayo Clinic, Rochester, MN; Nihar R. Desai, Yale Sch of Med, New Haven, CT

9:59 AM

The Comparative Effectiveness and Costs of Impella vs. Intra-Aortic Balloon Pump in the United States

**Amit P Amin** , Washington Univ Sch of Med, Saint Louis, MO; Sunil V Rao, Duke Univ Medical Ctr, Durham, NC; Jeptha P Curtis, Yale Univ, New Haven, CT; Brahmajee Kartik Nallamothu, Univ Michigan Health System, Ann Arbor, MI; Nihar R. Desai, Yale Sch of Med, New Haven, CT; Christian Andrew McNeely, Richard Bach, Washington Univ Sch of Med, Saint Louis, MO; John House, Charlotte, NC; Frederick A Masoudi, Univ of Colorado AMC, Aurora, CO; John Spertus, Mid America Heart Inst, Kansas City, MO; Hemant Kulkarni, South Texas Diabetes and Obesity Inst, Harlingen, TX; Duane S Pinto, Beth Israel Deaconess Medical Ctr, Boston, MA

10:06 AM

Discussant

Ranya N Sweis, Chicago, IL

10:10 AM

Panel Discussion

# Main Event

## HF.ME.405 - Amyloid Heart Disease: Emerging from the Shadows into YOUR Practice

#### Main Event II

### Sunday, November 17, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Margaret Redfield, Rochester, MN

9:00 AM

Moderator

Kelly Schlendorf, Nashville, TN

9:00 AM

A Patient With ATTR Cardiac Amyloid

Elizabeth A Hardin, Dallas, TX

9:20 AM

Making the Diagnosis in Your Practice: From History to Diagnostic Testing

Frederick Ruberg, Boston, MA

9:35 AM

Medications for ATTR Amyloid Cardiomyopathy: Ready for Prime Time!

Daniel P Judge, Charleston, SC

9:50 AM

When All Else Fails: The Role of Advanced Heart Failure Therapies

Michelle M Kittleson, Los Angeles, CA

10:05 AM

Panel Participant

Ronald Witteles, Stanford, CA

10:05 AM

Panel Participant

Rodney Falk, Boston, MA

10:05 AM

Panel Participant

Jignesh Patel, Beverly Hills, CA

# Sunday Morning Program

## NR.SMP.373 - 2019 Nursing Science in Review

#### 118C

### Sunday, November 17, 2019, 9:00 AM - 12:00 PM

9:00 AM

Moderator

Corrine Y Jurgens, Miller Place, NY

9:00 AM

Moderator

Dawn M Aycock, Atlanta, GA

9:00 AM

Effects of Family Sodium Watchers Program on Heart Failure Patient-Family Dyads

Misook Lee L CHUNG, Lexington, KY

9:20 AM

Q&A

9:45 AM

Q&A

9:50 AM

ENABLE CHF-PC: Comprehensive Heartcare for Patients and Caregivers

Marie Bakitas, Birmingham, AL

10:10 AM

Q&A

10:15 AM

Intermission

10:45 AM

Cognitive Behavioral Therapy for Insomnia in Stable Heart Failure

Nancy Redeker, West Haven, CT

11:05 AM

Q&A

11:30 AM

Q&A

11:35 AM

Self-Care Interventions Meta-Analysis for Heart Failure

Todd Ruppar, Chicago, IL

11:55 AM

Discussion

# Sunday Morning Program

## EP.SMP.524 - AHA's Strategic Goals in 2019 and Beyond (Part 1)

#### 201C

### Sunday, November 17, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Norrina B ALLEN, Chicago, IL

9:00 AM

Moderator

Catherine P Benziger, Duluth, MN

9:00 AM

Defining CV Health and the 2020 AHA Goals

Donald M Lloyd-Jones, Chicago, IL

9:15 AM

Obesity: Framing as a Behavior or a Disease?

Chiadi Ericson Ndumele, Baltimore, MD

9:30 AM

Making strides in reducing disparities

Quinn Capers, Columbus, OH

9:45 AM

Group Discussion

10:05 AM

Group Reports

# Sunday Morning Program

## VA.SMP.331 - VIRTUAL REALITY PE Response Team: Running the PE Gauntlet

#### 103C

### Sunday, November 17, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Gregory Piazza, Boston, MA

9:00 AM

Moderator

Victor F Tapson, Los Angeles, CA

9:00 AM

A 72-Year-Old Woman With PE and Refractory Shock

Karola Jering, Boston, MA

9:11 AM

A 56-Year-Old Man With Saddle PE and Hypotension

Arvind Pandey, Brookline, MA

9:22 AM

48-Year-Old Man With PE, Normal Blood Pressure, but RV Dysfunction and Positive Troponin

Behnood Bikdeli, New York, NY

9:44 AM

A Precision Response to PE: How New Technology and Fresh Strategies Can Change This Disease

Victor F Tapson, Los Angeles, CA

9:55 AM

Soup to Nuts: Implementing a PE Response Team

Geoffrey Barnes, Ann Arbor, MI

10:06 AM

Panel Participant

Patricia Thistlethwaite, La Jolla, CA

10:06 AM

Panel Participant

Jay S Giri, Philadelphia, PA

10:06 AM

Panel Participant

Irene M Lang, Vienna

10:06 AM

Panel Participant

Romain Chopard, Besancon, France

# Hall

## HT.06 - How to Do Health Tech Right: Best Practices to Regulation

#### Health Innovation Pavilion, Heart Hub, Science and Technology Hall, Level 2

### Sunday, November 17, 2019, 10:00 AM - 10:50 AM

10:00 AM

Moderator

Michael V McConnell, S San Fran, CA

10:10 AM

How-to for health tech AI and devices: Startup Experience

Steve Pham, Berkeley, CA

10:15 AM

The FDA perspective on digital health

Linda Ricci, Silver Spring, MD

10:20 AM

Cuffless blood pressure monitors - will they get approved?

Ramakrishna Mukkamala, East Lansing, MI

# Expert Theater

## ET.10 - Amgen, Inc.

#### Learning Studio 2, Booth # 7

### Sunday, November 17, 2019, 10:15 AM - 11:00 AM

This is not a CME/CE certified session

# Expert Theater

## ET.11 - OPEN

#### Learning Studio 1, Booth # 5

### Sunday, November 17, 2019, 10:15 AM - 11:00 AM

This is not a CME/CE certified session

# Abstract Rapid Fire Oral

## EP.RFO26 - Diabetes and CVD Risk Prediction

#### Science and Technology Hall A, Booth 605, Level 2

### Sunday, November 17, 2019, 10:30 AM - 11:20 AM

10:30 AM

Moderator

Muthiah Vaduganathan, Cambridge, MA

10:30 AM

Diabetes Prediction and Prevention

**Ernst J Schaefer** , Tufts Univ, Boston, MA; Masumi Ai, Tokyo Medical and Dental Univ, Tokyo, Japan; Joi Gleason, Tufts Univ, Boston, MA; Seiko Otokozawa, Sapporo General Hosp, Sapporo, Japan; Ching-ti Liu, L. Adrienne Cupples, Boston Univ Sch of Public Health, Boston, MA; Michael L Dansinger, Boston Heart Diagnostics, Framingham, MA

10:35 AM

Q & A

10:40 AM

Effects of Change in Glucose Intolerance Status on Risk of Incident Cardiovascular Disease: Tehran Lipid and Glucose Study

**Maryam Kabootari** , Farzad Hadaegh, Mitra Hasheminia, Fereidoun Azizi, Shahid Beheshti Univ of Medical Sciences, Tehran, Iran, Islamic Republic of

10:45 AM

Q & A

10:50 AM

Cardiovascular Effectiveness of Empagliflozin Compared to DPP4 Inhibitors and to GLP1 Receptor Agonists: Interim Analysis From the Empagliflozin Comparative Effectiveness and Safety (EMPRISE) Study

**Elisabetta Patorno** , Ajinkya Pawar, Jessica Franklin, Mehdi Najafzadeh, Brigham and Women's hospital, Boston, MA; Deborah Wexler, Massachusetts General Hosp, Boston, MA; Anouk Déruaz-Luyet, Boehringer Ingelheim Intl GmbH, Ingelheim am Rhein, Germany; Kimberly Brodovicz, Boehringer Ingelheim, Ridgefield, CT; Lily Bessette, Brigham & Women's Hosp, Boston, MA; Sebastian Schneeweiss, Brigham and Women's Hosp, Boston, MA

10:55 AM

Q & A

11:00 AM

Bempedoic Acid and Glycemic Control: A Pooled Analysis of 4 Phase 3 Clinical Trials

**Lawrence A Leiter** , Li Ka Shing Knowledge Inst, St. Michael's Hosp, Univ of Toronto, Toronto, ON, Canada; Maciej Banach, Medical Univ of Łódź, Łódź, Poland; Alberico L Catapano, Univ of Milan and IRCCS Multimedica, Milan, Italy; P. Barton Duell, Oregon Health Sciences Univ, Portland, OR; Antonio Gotto, Weill Cornell Medical Coll, New York, NY; Ulrich Laufs, Leipzig Univ, Leipzig, Germany; G. B. John Mancini, Univ of British Columbia, Vancouver, BC, Canada; Kausik K Ray, Imperial Coll London, London, United Kingdom; Jeffrey C Hanselman, Zhan Ye, Esperion Therapeutics, Inc., Ann Arbor, MI; Harold E. Bays, Louisville Metabolic and Atherosclerosis Res Ctr, Louisville, KY

11:05 AM

Q & A

11:10 AM

Variability in Hemoglobin A1c and Risk of Incident Heart Failure Among Patients With Type 2 Diabetes Mellitus

**Matthew W Segar** , Kershaw V Patel, Univ of Texas Southwestern Medical Ctr, Dallas, TX; Muthiah Vaduganathan, Brigham and Women's Hosp Heart and Vascular Ctr, Boston, MA; Javed Butler, Univ of Mississippi Medical Ctr, Jackson, MS; Gregg C Fonarow, Ronald Reagan UCLA Medical Ctr, Los Angeles, CA; Darren K McGuire, Ambarish Pandey, Univ of Texas Southwestern Medical Ctr, Dallas, TX

11:15 AM

Q & A

# Abstract Rapid Fire Oral

## PH.RFO23 - Novel Experimental Therapies for Pulmonary Arterial Hypertension

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 10:30 AM - 11:20 AM

10:30 AM

Moderator

Paul B Yu, Boston, MA

10:30 AM

Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension -High-throughput Screening of 5,562 Compounds-

**Ryo Kurosawa** , Kimio Satoh, Tohoku Univ, Sendai, Japan; Nobuhiro Kikuchi, Tohoku Univ, Aoba-ku, Sendai, Miyagi, Japan; Taijyu Satoh, Pittsburgh university, Pittsburgh, PA; Junichi Omura, Laval university, Quebec City, QC, Canada; Masamichi Nogi, Shinichiro Sunamura, Mohammad Abdul Hai Siddique, M. Elias Al-Mamun, Tohoku Univ, Sendai, Japan; Nobuhiro Yaoita, Tohoku Univ Hosp, Sendai, Japan; Toru Shimizu, Tohoku Univ Graduate Sch of Med, Sendai, Japan; Hiroaki Shimokawa, Tohoku Univ, Sendai City, Japan

10:40 AM

Inhibition of Fatty Acid Synthase in Vascular Smooth Muscle Cell Ameliorates Abnormal Cell Proliferation and Experimental Pulmonary Arterial Hypertension in Mice

**Hiroki Matsui** , Hiroaki Sunaga, Satoko Furukawa, Nozomi Furukawa, Gunma Univ, Maebashi, Japan; Norimichi Koitabashi, Tatsuya Iso, Gunma Univ, Maebashi Gunma, Japan; Tomoyuki Yokoyama, Gunma Univ, Maebashi, Japan; Masahiko Kurabayashi, Gunma Univ, Gunma, Japan

10:50 AM

In Vivo Efficacy of a Novel, Inhaled Pdgfra/b Inhibitor, Gb002, in The Rat Monocrotaline and Pneumonectomy Model of Pulmonary Arterial Hypertension

**Ravi Sitapara** , Debbie Slee, Luisa Salter-Cid, Gossamer Bio, San Diego, CA; Larry Zisman, Gossamer Bio Inc., San Diego, CA

11:00 AM

Beneficial Effects of Ferric Carboxymaltose in Patients With Pulmonary Arterial Hypertension and Iron Deficiency: A Long-term Study

**Tilmann T Kramer** , Clinic III for Internal Med, Cologne, Germany; Thomas Viethen, Clinic III for Internal Med, Univ of Cologne, Cologne, Germany; Kristiana Natsina, Felix Gerhardt, Henrik Ten-Freyhaus, Daniel Dumitrescu, Martin Hellmich, Stephan Baldus, Stephan Rosenkranz, Clinic III for Internal Med, Cologne, Germany

11:10 AM

Sensitize Pulmonary Artery Smooth Muscle Cells (PASMC) to Oxidative Stress by 8oxoguanine Hydrolase Nudt1 Inhibition Has a Therapeutic Potential in Pulmonary Arterial Hypertension

**Geraldine Vitry** , Marie-Claude Lampron, CRIUCPQ, Quebec, QC, Canada; Alice Bourgeois, CRIUCPQ, Québec, QC, Canada; Renee Paradis, CRIUCPQ, Quebec, QC, Canada; Valerie Nadeau, CRIUCPQ, Ville de Québec, QC, Canada; Sandra Breuils-Bonnet, CRIUCPQ, Quebec, QC, Canada; Eve Tremblay, CRIUCPQ, Québec, QC, Canada; Sandra Martineau, Mark Orcholski, CRIUCPQ, Quebec, QC, Canada; Caroline Lambert, IUCPQ Res Ctr, Quebec, QC, Canada; Steeve Provencher, Laval Univ; Olivier Boucherat, IUCPQ Res Ctr, Quebec, QC, Canada; Sebastien Bonnet, Quebec Heart and Lung institute, Quebec, QC, Canada; Roxane Paulin, CRIUCPQ, Québec, QC, Canada

# Abstract Rapid Fire Oral

## GE.RFO17 - Polygenic Risk Scores

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 10:30 AM - 11:20 AM

10:30 AM

Moderator

Kiran Musunuru, Philadelphia, PA

10:30 AM

Risk of Myocardial Infarction in Carriers of Familial Hypercholesterolemia Mutations is Modified by Common Variant Genetic Background or Adherence to a Healthy Lifestyle

**Akl C. Fahed** , Massachusetts General Hosp, Boston, MA; Minxian Wang, Broad Inst of MIT and Harvard, Cambridge, MA; Mark Chaffin, Broad Inst of MIT and Harvard, Cambridge; Alexander G Bick, Harvard Medical Sch, Boston, MA; Candace Patterson, Broad Inst of MIT and Harvard, Cambridge, MA; Pradeep Natarajan, Massachusetts General Hosp, Boston, MA; Matthew Lebo, Partners Healthcare, Boston, MA; Puneet Batra, Broad Inst of MIT and Harvard, Cambridge, MA; Kenney Ng, IBM Res, Cambridge, MA; Patrick Thomas Ellinor, Massachusetts General Hosp, Boston, MA; Anthony Andrew Philippakis, Broad Inst, Cambridge, MA; Sekar Kathiresan, Verve Therapeutics, Cambridge, MA; Amit V Khera, Massachusetts General Hosp, Cambridge, MA

10:35 AM

Q & A

10:40 AM

Performance of a Genome-Wide Polygenic Risk Score to Predict Coronary Events in Patients With Diabetes Without Prior Myocardial Infarction

**Nicholas A Marston** , Brigham and Women's Hosp, Boston, MA; Carolina Roselli, Broad Inst, Cambridge, MA; Francesco Nordio, Univ of Milan, Milan, Italy; Yared Gurmu, TIMI Study Group, Boston, MA; Steven A Lubitz, Massachusetts General Hosp, Boston, MA; Benjamin M Scirica, Brigham and Women's Hosp, Boston, MA; Deepak L Bhatt, Brigham and Womens Hosp, Boston, MA; Itamar Raz, Diabetes Medical Ctr, Tel Aviv, Israel; Ofri Mosenzon, Hadassah Medical Ctr, Jerusalem, Israel; Daniel Lindholm, Uppsala Clinical Res Ctr, Uppsala, Sweden; Eugene Braunwald, Brigham and Women's Hosp, Boston, MA; Marc S Sabatine, TIMI Study Group, Boston, MA; Patrick Thomas Ellinor, Massachusetts General Hosp, Boston, MA; Christian Ruff, Timi Study Group, Boston, MA

10:45 AM

Q & A

10:55 AM

Q & A

11:00 AM

Temporal and Secular Trends Attenuate the Performance of a Polygenic Risk Score for Coronary Heart Disease

**Jonathan D Mosley** , Mingjian Shi, Wei-Qi Wei, Nancy Cox, C Michael Stein, Dan M Roden, Quinn Wells, Vanderbilt Univ Medical Ctr, Nashville, TN

11:05 AM

Q & A

11:10 AM

Performance Comparison of Polygenic Risk Scores for Atrial Fibrillation Among Ethnicities in the Multi-Ethnic Study of Atherosclerosis

**Christoffel J Van Niekerk** , Scripps Clinic, La Jolla, CA; Nathan Wineinger, Raquel Dias, Ali Torkamani, Scripps Res, La Jolla, CA; Evan D Muse, Scripps Clinic, La Jolla, CA

11:15 AM

Q & A

# Abstract Rapid Fire Oral

## IM.RFO20 - The Tell-Tale Heart: MRI of Non-Ischemic Cardiomyopathies

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 10:30 AM - 11:20 AM

10:30 AM

Prognostic Value of T1 Mapping and Feature Tracking by Cardiac Magnetic Resonance in Patients With Suspected Non-Ischemic Cardiomyopathy

**Ayako Seno** , Iqra Qamar, Panagiotis Antiochos, Brigham and Women's Hosp, Boston, MA; Yin Ge, Brigham And Women's Hosp, Boston, MA; Yi-Yun Chen, Ayaz Aghayev, Michael Steigner, Ron Blankstein, Michael Jerosch-Herold, Raymond Y Kwong, Brigham and Women's Hosp, Boston, MA

10:40 AM

Impaired Myocardial Perfusion Reserve is Associated With Adverse Cardiovascular Events in Patients With Dilated Cardiomyopathy

**Daniel Hammersley** , Imperial Coll, London, United Kingdom; Brian Halliday, Imperial Coll, London, London, United Kingdom; Ankur Gulati, Royal Brompton Hosp, London, United Kingdom; Tevfik F Ismail, Kings Coll London, London, United Kingdom; Aamir Ali, Royal Brompton Hosp, London, United Kingdom; Li-Yueh Hsu, Natl Insts of Health, Bethesda, MD; Richard Jones, Upasana Tayal, Royal Brompton Hosp, London, United Kingdom; Amrit Lota, Imperial Coll London, London, United Kingdom; Rick Wage, Peter Gatehouse, David Firmin, Dominique Auger, Royal Brompton Hosp, London, United Kingdom; Ruth Owen, London Sch of Hygeine and Tropic, London; Dudley J Pennell, Royal Brompton Hosp, London; Andrew E Arai, NIH NHLBI, Bethesda, MD; Sanjay K Prasad, Royal Brompton Hosp, London, United Kingdom

10:50 AM

The Prevalence and Prognostic Impact of Right Ventricular Abnormalities on Cardiovascular Magnetic Resonance Imaging in Patients With Sarcoidosis

**Pratik Velangi** , Univ of Minnesota, Minneapolis, MN; Ko-hsuan Amy Chen, Univ of Minnesota, San Jose, CA; Felipe Kazmirczak, Osama Okasha, Lisa Von Wald, Univ of Minnesota, Minneapolis, MN; Henri Roukoz, Univ Minnesota, Minneapolis, MN; Jeremy Markowitz, Prabhjot S Nijjar, Maneesh Bhargava, David Perlman, Mehmet Akcakaya, Chetan Shenoy, Univ of Minnesota, Minneapolis, MN

11:00 AM

Assessing the Accuracy of the Petersen Criteria for Left Ventricular Non-Compaction With a Novel Thresholding Technique: Long Term Clinical Follow Up

**Giuseppe Femia** , Christopher Semsarian, David Richmond, Royal Prince Alfred Hosp, Sydney, Australia; Preeti Choudhary, Westmead Hosp, Sydney, Australia; Samantha Barratt Ross, Centenary Inst, Sydney, Australia; Danyi Zhu, Univ of Sydney, Darlington, Australia; Rajesh Puranik, Royal Prince Alfred Hosp, Sydney, Australia

11:10 AM

Left Ventricular Function Recovery In Peripartum Cardiomyopathy: A Cardiovascular Magnetic Resonance Study By Myocardial T1 And T2 Mapping

**Yaodan Liang** , Beijing Hosp, Beijing, China; Yuanwei Xu, Dept of Cardiology, West China Hosp, Sichuan Univ, Chengdu, China; Weihao Li, Ke Wan, WestChina Hosp, Chengdu, China; Qing Zhang, Yucheng Chen, West China Hosp, Chengdu, China

# Moderated Digital Posters

## HF.MDP28 - Acute Decompensated Heart Failure

#### Moderated Posters 2, Science and Technology Hall

### Sunday, November 17, 2019, 10:30 AM - 11:20 AM

10:30 AM

Moderator

Eldrin F Lewis, Boston, MA

10:30 AM

Splanchnic Congestion and the Everest Score for Assessing Clinical Outcomes in Patients With Acute Decompensated Heart Failure

**Nadia Bouabdallaoui** , William Beaubien-Souligny, Essaid Oussaid, Christine Henri, Normand Racine, Andre Y Denault, Montreal Heart Inst, Montreal, QC, Canada; Jean L. Rouleau, Toronto General Hosp, Toronto, ON, Canada

10:35 AM

Q & A

10:40 AM

Worsening Renal Function During Intensive Volume Removal is Driven by Renin-Angiotensin-Aldosterone System Activation

**Matthew Griffin** , Yale Sch of Med, New Haven, CT; Juan Ivey-Miranda, Hosp de Cardiologia, Insto Mexicano del Seguro Social, Mexico City; Veena Rao, Yale Sch of Med, New Haven; James Fleming, Nicole Gomez, Joslyn Barnett, Megan Pattoli, Emily Wycallis, Devin Mahoney, Anvin Thomas, Griffin Struyk, Yale Sch of Med, New Haven, CT; Jeffrey M Testani, Yale Sch of Med, Guilford, CT

10:45 AM

Q & A

10:50 AM

**The Association Between Congestion and Outcomes for Patients Treated With Sacubitril-Valsartan Compared to Enalapril in the** PIONEER-HF **Trial**

**Marc D Samsky** , Duke Univ, Durham, NC; Eric Jose Velazquez, Yale Univ Sch of Med, New Haven, CT; Eugene Braunwald, David A Morrow, Brigham and Women's Hosp, Boston, MA; Hillary Mulder, Duke Clinical Res Inst, D, Durham, NC; Hrishikesh Chakraborty, Duke Univ, Durham, NC; Carol Duffy, Novartis Pharmaceuticals, East Hanover, NJ; Ricardo Rocha, Novartis Pharmaceuticals Corporatio, East Hanover, NJ; Andrew Patrick Ambrosy, Duke Univ Medical Ctr, San Francisco, CA; Adam David Devore Sr., Duke Clinical Res Inst, Durham, NC

10:55 AM

Q & A

11:00 AM

Prognostic Significance of Physical Trigger Type in Takotsubo Cardiomyopathy

**Kathryn Cardoza** , Stanford Univ, Stanford, CA; Arash Nayeri, Alexander Yuen, Andrea MacDonald, Cher Huang, UCLA, Los Angeles, CA; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; Quinn Wells, Vanderbilt Univ, Nashville, TN; Kamran Shamsa, UCLA, Los Angeles, CA

11:05 AM

Q & A

11:10 AM

TRACP5b is Associated With High Mortality in Hospitalized Patients With Heart Failure

**Satoshi Abe** , Akiomi Yoshihisa, Fukusima Medical Univ, Fukushima, Japan; Yusuke Kimishima, Fukushima Medical Univ, Fukushima City, Japan; Yu Sato, Yuki Kanno, Fukushima Medical Univ, Fukushima, Japan; Tetsuro Yokokawa, Fukusima Medical Univ, Fukushima, Japan; Tomofumi Misaka, Fukushima Medical Univ, Fukushima, Japan; Takamasa Sato, Fukusima Medical Univ, Fukushima, Japan; Masayoshi Oikawa, Atsushi Kobayashi, Fukushima Medical Univ, Fukushima, Japan; Takayoshi Yamaki, Fukusima Medical Univ, Fukushina, Japan; Hiroyuki Kunii, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi, Fukusima Medical Univ, Fukushima, Japan

11:15 AM

Q & A

# Moderated Digital Posters

## IM.MDP25 - Coronary CT: Impact of Gender, Race and Ethnicity on Heart Health

#### Moderated Posters 1, Science and Technology Hall

### Sunday, November 17, 2019, 10:30 AM - 11:20 AM

10:30 AM

Sex Differences of Coronary Physiology Can Be Justified by Fractional Myocardial Mass

**Joon Ho Ahn** , Hyung Yoon Kim, Chonnam Natl Univ Hosp, Gwangju-si, Korea, Republic of; Kye Hun Kim, Chonnam Natl Univ Hospita, Gwangju; Jae Yeong Cho, Chonnam Natl Univ Hosp, Gwangju; Hyun Ju Yoon, Chonnam Natl Univ Hosp, Gwangju-si, Korea, Republic of; Hyukjin Park, Chonnam Natl Univ Hosp, Gwangju; Jin-Ho Choi, Samsung Medical Ctr, Seoul

10:35 AM

Q & A

10:40 AM

Coronary Artery Calcium and the Sex-Specific Competing Risk of Cardiovascular versus Cancer Mortality: The CAC Consortium

**Omar Dzaye** , Johns Hopkins Univ, Baltimore, MD; Mahmoud S Al Rifai, Univ of Kansas, Wichita, KS; Zeina Dardari, Johns Hopkins Univ, Baltimore, MD; Leslee J Shaw, Emory Univ, Atlanta, GA; Mouaz H Al-Mallah, Houston Methodist Hosp, Pearland, TX; Catherine Marshall, Johns Hopkins Univ, Baltimore, MD; Alan Rozanski, Mount Sinai, St Luke's Hosp, New York, NY; Martin B. Mortensen, Aarhus Univ Hosp, Aarhus, Denmark; Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD; John A Rumberger, The Princeton Longevity Ctr, Hopewell, NJ; Daniel S. Berman, Cedars-Sinai Medical Ctr, LA, CA; Matthew J Budoff, Los Angeles Biomedical Researc, Torrance, CA; Michael D. Miedema, Minneapolis Heart Inst and Fndn, Minneapolis, MN; Khurram Nasir, Johns Hopkins Univ, Baltimore, MD; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; Seamus Paul Whelton, Johns Hopkins Univ, Baltimore, MD

10:45 AM

Q & A

10:50 AM

Effect of Menopausal Hormonal Therapy and Coronary Artery Calcium on Volumetric Bone Mineral Density by Serial Computed Tomography Angiography

**Chandana Shekar** , April Kinninger, Lucas Cespedes, Eranthi Jayawardena, Lavanya Cherukuri, Divya Birudaraju, Matthew J Budoff, Sion K Roy, LA Biomed at Harbor UCLA, Torrance, CA; KEEPS study Investigators and Staff

10:55 AM

Q & A

11:00 AM

Change in Coronary Artery Calcium (cac) Volume and Density With Direct Plaque Measurements: Findings From the Masala Study

**Alka M Kanaya** , Feng Lin, UCSF, San Francisco, CA; Isac C Thomas, Univ of California San Diego, La Jolla, CA; Julie Denenberg, UCSD, La Jolla, CA; Namratha Kandula, Northwestern Univ, Chicago, IL; Matthew J Budoff, Los Angeles Biomedical Res, Torrance, CA; Michael H Criqui, UCSD, La Jolla, CA

11:05 AM

Q & A

11:10 AM

Racial Variability in Severity of Coronary Calcification Among Patients Undergoing Percutaneous Coronary Intervention: Results From a Single-Center Multiethnic Registry

**Solomon Bienstock** , Rajeev Samtani, Melissa Aquino, Usman Baber, Joseph Sweeny, Nitin Barman, Jason C Kovacic, Roxana Mehran, Annapoorna Kini, Samin K. Sharma, Martin Goldman, Mount Sinai Medical Ctr, New York, NY

11:15 AM

Q & A

# Moderated Digital Posters

## LF.MDP46 - Health Disparities and Underserved Populations

#### Moderated Posters 8, Science and Technology Hall

### Sunday, November 17, 2019, 10:30 AM - 11:20 AM

10:30 AM

Syndemic of Unhealthy Alcohol Use, Smoking, and Depressive Symptoms is Associated With Incident Cardiovascular Disease Among Those With and Without Hiv-Infection

**Natalie Chichetto** , Suman Kundu, Matthew S Freiberg, Vanderbilt Univ Medical Ctr, Nashville, TN; Adeel Butt, Weill-Cornell Medical Coll, New York, NY; Stephen Crystal, Rutgers Univ, New Brunswick, NJ; Robert Cook, Univ of Florida, Gainesville, FL; R. Scott Braithwaite, New York Univ, New York, NY; David Fiellin, Yale Univ, New Haven, CT; Maria Khan, New York Univ Sch of Med, New York, NY; Kendall Bryant, Natl Inst on Health, Bethesda, MD; Julie Gaither, Yale Univ, New Haven, CT; Shirish Barve, Univ of Louisville, Louisville, KY; Kristina Crothers, Univ of Washington, Seattle, WA; Roger Bedimo, The Univ of Texas Southwestern Medical Ctr, Dallas, TX; Alberta L Warner, VA Greater Los Angeles, Los Angeles, CA; Hilary A. Tindle, Vanderbilt Univ Medical Ctr, Nashville, TN

10:35 AM

Q & A

10:40 AM

Depression Screening Patterns Demonstrate Disparities in Outpatients With Coronary Artery Disease

**Adam Prince** , Umair Ahmed, Northwell Health, Lenox Hill Hosp, New York, NY; Nikhil Sharma, Univ of Pennsylvania, Philadelphia, PA; Rachel Bond, Northwell Health, Lenox Hill Hosp, New York, NY

10:45 AM

Q & A

10:50 AM

Positive Impact of Cardiovascular Health Promotion Through Diet and Physical Activity: Results From a Community-Based Trial Among Mothers With Young Children in a Semi-Urban Community of Nepal

**Natalia Oli** , Abhinav Vaidya, Kathmandu Medical Coll, Kathmandu, Nepal; Gabriele Eiben, Univ Skovde, Skövde, Sweden; Alexandra Krettek, Univ Skovde, Skovde, Sweden

10:55 AM

Q & A

11:00 AM

Cardiovascular Health Status and Lifetime Risk of Heart Failure Among White and Black US Adults

**Sadiya S. Khan** , Northwestern Univ, Oak Park, IL; Hongyan Ning, Amanda Paluch, Victor Zhong, Norrina B Allen, Mercedes R Carnethon, John T Wilkins, Donald M Lloyd-Jones, Northwestern Univ, Chicago, IL

11:05 AM

Q & A

11:10 AM

Metabolic and Inflammatory Risk During Lipid-Lowering and Lifestyle Therapy in Underserved Populations

Michael P Chu, Daniel A Isquith, Susan McKeeth, Jayne Williamson, Moni B Neradilek, Univ of Washington, Seattle, WA; Gina Many, Pacific Northwest Univ, Yakima, WA; **Xue-Qiao Zhao** , Univ of Washington, Seattle, WA

11:15 AM

Q & A

# Moderated Digital Posters

## HF.MDP40 - Heart Failure II

#### Moderated Posters 6, Science and Technology Hall

### Sunday, November 17, 2019, 10:30 AM - 11:20 AM

10:30 AM

Moderator

Sharlene Day, Ann Arbor, MI

10:30 AM

Differences in Contractile Protein Expression Produce Distinct Heart Failure Phenotypes

**Melissa Lyle** , Young Soo Han, Frank Brozovich, Mayo Clinic, Rochester, MN

10:35 AM

Q & A

10:40 AM

Local Action of Neprilysin Exacerbates Hypertensive Cardiac Remodeling

**Hitoshi Nakagawa** , Nara Medical Univ, Kashihara, Japan; Takuya Kumazawa, Nara Medical Univ, Kashihara Nara, Japan; Kenji Onoue, Yasuki Nakada, Tomoya Nakano, Nara Medical Univ, Kashihara, Japan; Satomi Ishihara, Nara Medical Univ, Nara-ken Kashihara-shi, Japan; Naoto Minamino, Natl Cereb Cardiovascul Ctr, Suita, Osaka, Japan; Nobuhisa Iwata, Nagasaki Univ, Nagasaki, Japan; Tomoya Ueda, Nara Medical Univ, Nara, Japan; Tsunenari Soeda, Nara Medical Univ, Kashihara, Japan; Makoto Watanabe, Nara Medical Univ, Kashihara Nara, Japan; Rika Kawakami, First Dept of Internal Med, Nara Medica, Kashihara, Japan; Yoshihiko Saito, Nara Medical Univ, Kashihara, Japan

10:45 AM

Q & A

10:50 AM

Reduced Fatty Acid Uptake Aggravates Cardiac Contractile Dysfunction in Streptozotocin-induced Diabetic Cardiomyopathy

Yogi Umbarawan, Gunma Univ, Maebashi, Japan; **Ryo Kawakami** , Gunma Univ, Maebashi, Gunma, Japan; Tatsuya Iso, Gunma Univ Graduate Sch Med, Maebashi Gunma, Japan; Norimichi Koitabashi, Gunma Univ Sch Med, Maebashi Gunma, Japan; Hiroaki Sunaga, Gunma Univ Graduate Sch of Med, Maebashi, Japan; Hiroki Matsui, Gunma Univ, Gunma, Japan; Masahiko KURABAYASHI, Gunma Univ Grad Sch of Med, Gunma, Japan

10:55 AM

Q & A

11:00 AM

**Enhanced Mitochondrial Ca** 2+ **Efflux via the Mitochondrial Na** + **/Ca** 2+ **Exchanger Attenuates Pathological Cardiac Remodeling and Hypertrophy in Non-Ischemic Heart Failure**

**Joanne F. Garbincius** , Timothy S. Luongo, Devin W. Kolmetzky, Alycia N. Hildebrand, Rajika Roy, John W. Elrod, Temple Univ, Philadelphia, PA

11:05 AM

Q & A

11:10 AM

Hybrid Optical and CT Imaging Reveals Increased Matrix Metalloprotease Activity and Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice

Bibi S. van Thiel, Yanto Ridwan, Martine de Boer, Marion G.J. de Kleijnen, Nicole van Vliet, Paula M. van Heijningen, Erasmus Medical Ctr, Rotterdam, Netherlands; Wilbert P Vermeij, Prinses Maxima Centrum, Utrecht, Netherlands; Jan H Danser, Erasmus MC, Rotterdam, Netherlands; Roland Kanaar, Dirk J. Duncker, Jan H.J. Hoeijmakers, **Ingrid Van Der Pluijm** , Erasmus Medical Ctr, Rotterdam, Netherlands; Jeroen Essers, Erasmus MC, Rotterdam, Netherlands

11:15 AM

Q & A

# Moderated Digital Posters

## GE.MDP37 - Mend Thyself

#### Moderated Posters 5, Science and Technology Hall

### Sunday, November 17, 2019, 10:30 AM - 11:20 AM

10:30 AM

Moderator

Doris A Taylor, Houston, TX

10:30 AM

The Brand-New Compound Activates Cell Cycle of Induced Pluripotent Stem Cell Derived Cardiomocytes, and Promotes Efficient Cardiac Engraftment

**Manabu Kasamoto** , Takeshi Hatani, Kyoto Univ, Kyoto, Japan; Shunsuke Funakoshi, Ctr for IPS Cell Res and AP, Kyoto, Japan; Yoshinori Yoshida, Kyoto Univ, Kyoto, Japan; Takeshi Kimura, Kyoto Univeristy, Kyoto, Japan

10:35 AM

Q & A

10:40 AM

Intrapericardial Injection of Hydrogels Derived From Decellularized Cardiac Extracellular Matrix Loaded With Mesenchymal Stromal Cells and Their Secretome: A Novel Proposal of Therapeutic Approach to Cytostatics-induced Dilated Cardiomyopathy

**Tácia TA Liguori** , Gabriel R Liguori, Viktor Sinkunas, Cristiano J Correia, Raphael Dos Santos Coutinho e Sil, Heart Inst (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, Univ de Sao Paulo, Sao Paulo, SP, BR, Sao Paulo, Brazil; Cristina P Camargo, Hosp das Clinicas HCFMUSP, Faculdade de Medicina, Univ de Sao Paulo, Sao Paulo, SP, BR, Sao Paulo, Brazil; Fernando L Zanoni, Vera D Aiello, Heart Inst (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, Univ de Sao Paulo, Sao Paulo, SP, BR, Sao Paulo, Brazil; Martin C Harmsen, Univ of Groningen, Univ Medical Ctr Groningen, the Netherlands, Groningen, Netherlands; Luiz Felipe P Moreira, Heart Inst (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, Univ de Sao Paulo, Sao Paulo, SP, BR, Sao Paulo, Brazil

10:45 AM

Q & A

10:50 AM

Fibroblast Transition to an Endothelial "Trans" State Improves Cell Reprogramming Efficiency and Post-Infarct Cardiac Function

**Megumi Mathison** , Deepthi Sanagasetti, Vivek P Singh, Anna Jang, Aarthi Pugazenthi, Jaya Pratap Pinnamaneni, Kai Wang, Jianchang Yang, Todd K Rosengart, Baylor Coll of Med, Houston, TX

10:55 AM

Q & A

11:00 AM

**Predictors of Long-Term Outcome Following Transendocardial Cd34** + **Cell Transplantation in Chronic Heart Failure Patients**

**Gregor Poglajen** , Sabina Frljak, Gregor Zemljic, Andraz Cerar, Renata Okrajšek, Miran Sebestjen, Vesna Andročec, Bojan Vrtovec, UMC Ljubljana, Ljubljana, Slovenia

11:05 AM

Q & A

11:10 AM

Building Mycoplasma Checking System Using Image Based Deep-learning in Regeneration Medicine Products

**Hiroko Iseoka** , Osaka Univ, Osaka, Japan; Shigeru Miyagawa, Osaka Univ, Suita, Japan; Masao Sasai, Osaka university, Osaka, Japan; Satoshi Date, Hiroto Ayame, Dai Nippon Printing Co., Ltd., Tokyo, Japan; Azusa Nishida, Yoshiki Sawa, Osaka Univ, Osaka, Japan

11:15 AM

Q & A

# Moderated Digital Posters

## AT.MDP34 - Monocytes, Macrophages and Atherosclerosis

#### Moderated Posters 4, Science and Technology Hall

### Sunday, November 17, 2019, 10:30 AM - 11:20 AM

10:30 AM

Plasminogen Facilitates Foam Cell Formation by Macrophages Utilizing H2B and PAR1

**Lahoucine Izem** , Cleveland Clinic Fndn, Cleveland, OH; Katarzyna Bialkowska, Elzbieta Pluskota, Cleveland Clinic, Cleveland, OH; Marvin T Nieman, Case Western Reserve Univ, Cleveland, OH; Edward F Plow, Lerner Res Inst Cleveland Clinic, Cleveland, OH

10:35 AM

Q & A

10:40 AM

Eukaryotic Elongation Factor 2 Kinase Regulates Cholesterol Uptake by Macrophages via Cd36 Scavenger Receptor Expression

**Sanuja Fernando** , The Univ of Adelaide, Adelaide, Australia; Nisha Schwarz, Lauren Sandeman, Thalia Skoumbourdis, Jonar Zareh, SAHMRI, Adelaide, Australia; Anna Williamson, The Univ of Adelaide, Adelaide, Australia; Belinda Di Bartolo, SAHMRI, Adelaide, Australia; Joanne Tsui Ming Tan, Christina A Bursill, SAHMRI, Adelaide, SA, Australia; Stephen Nicholls, Christopher Proud, Peter J Psaltis, SAHMRI, Adelaide, Australia

10:45 AM

Q & A

10:50 AM

Alternatively Activated Macrophage Exosomes: New Mediators to Control Hematopoiesis & Atherosclerosis

**Laura Bouchareychas** , Univ of California San Francisco & Northern California Inst for Res and Education, San Francisco, CA; Phat Duong, Northern California Inst for Res and Education, San Francisco, CA; Sergio Covarrubias, Univ of California Santa Cruz, Santa Cruz, CA; Eric Alsop, The Translational Genomics Res Inst (TGen), Phoenix, AZ; Allen Chung, Michael Gomes, David Wong, Northern California Inst for Res and Education, San Francisco, CA; Bessie Meechoovet, The Translational Genomics Res Inst (TGen), Phoenix, AZ; Allyson Capili, Univ of California Santa Cruz, Santa Cruz, CA; Ryo Yamamoto, Hiromitsu Nakauchi, Stanford Univ Sch of Med, Lorry I, Stanford, CA; Michael McManus, Univ of California San Francisco, San Francisco, CA; Susan Carpenter, Univ of California Santa Cruz, Santa Cruz, CA; Kendall Van Keuren-Jensen, The Translational Genomics Res Inst (TGen), Phoenix, AZ; Robert Raffai, Univ of California San Francisco, San Francisco, CA

10:55 AM

Q & A

11:00 AM

**CD163** + **Alternative Macrophage Inhibits Atherosclerotic Calcification via Enhancement of Hyaluronan Production in Vascular Smooth Muscle Cells**

**Atsushi Sakamoto** , CVPath Inst, Gaithersburg, MD; Liang Guo, CVPath institute, Gaithersburg, MD; Ka Hyun Paek, Raquel Fernandez, Anne Cornelissen, CVPath Inst, Gaithersburg, MD; Hiroyuki Jinnouchi, CVPath institute, Gaithersburg, MD; Yu Sato, Salome Kuntz, CVPath Inst, Gaithersburg, MD; Frank D Kolodgie, Renu Virmani, Aloke V Finn, CVPath institute, Gaithersburg, MD

11:05 AM

Q & A

11:10 AM

Semaphorin 3F Inhibits Transendothelial Monocyte Migration and Protects Against Atherosclerosis

**Chutima Rattanasopa** , Crystal Kok Yan Pang, Duke Nus Medical Sch, SINGAPORE, Singapore; Elisa Liehn, Inst For Molec Cardiovascular Res, Stolberg, Germany; David Castano, Roshni R Singaraja, Translational Lab in Genetic Med, SINGAPORE, Singapore; Sujoy Ghosh, Duke Nus Medical Sch, SINGAPORE, Singapore

11:15 AM

Q & A

# Moderated Digital Posters

## HY.MDP31 - Recent Advances in Clinical Hypertension

#### Moderated Posters 3, Science and Technology Hall

### Sunday, November 17, 2019, 10:30 AM - 11:20 AM

10:30 AM

Moderator

John Jefferies, MI

10:30 AM

Empagliflozin in Resistant Hypertension: Findings From the Empa-reg Outcome Trial

**Joao Pedro Ferreira** , Univ de Lorraine, Vandoeuvre-les-Nancy, France; David Fitchett, St Michael's Hosp, Toronto, ON, Canada; Anne Pernille Ofstad, Boehringer Ingelheim, Asker, Norway; Bettina J Kraus, Univ Hosp Wuerzburg, Wuerzburg, Germany; Christoph Wanner, Univ Hosp, Würzburg, Germany; Isabella Zwiener, Boehringer Ingelheim Pharma GmbH, Ingelheim am Rhein, Germany; Sabine Lauer, Boehringer Ingelheim Pharma GmbH & Co.KG, Ingelheim am Rhein, Germany; Jyothis Thomas George, Boehringer Ingelheim Pharma GmbH, Ingelheim, Germany; Patrick Rossignol, Univ de Lorraine, Nancy, France; Faiez Zannad, Univ de Lorraine, Vandoeuvre Les Nancy, France

10:35 AM

Q & A

10:40 AM

Racial/Ethnic Disparities in the Trends of the Prevalence, Awareness, Treatment, and Control of Hypertension Among Young American Adults

**Vibhu Parcha** , Univ of Alabama, Birmingham, AL; Nirav Patel, Univ of Alabama at Birmingham, Birmingham, AL; Rajat Kalra, Univ of Minnesota Cardiovascular Div, Minneapolis, MN; Anirudh Bhargava, UAB Internal Med, Birmingham, AL; Garima Arora, Pankaj Arora, Univ of Alabama at Birmingham, Birmingham, AL

10:45 AM

Q & A

10:50 AM

Long-term Effects on Cardiovascular Events and Costs of Home Blood Pressure Telemonitoring With Pharmacist Management in Patients With Uncontrolled Hypertension

**Karen L Margolis** , Steven P Dehmer, Michael V Maciosek, JoAnn M Sperl-Hillen, Stephen E Asche, Anna R Bergdall, Healthpartners Inst, Minneapolis, MN; Beverly B Green, Kaiser Permanente, Seattle, WA; Rachel A Nyboer, Pamala A Pawloski, Nicole K Trower, Patrick J O'Connor, Healthpartners Inst, Minneapolis, MN

10:55 AM

Q & A

11:00 AM

Effect of Intensive Blood Pressure Control on Residual Lifespan in the SPRINT Trial

**Muthiah Vaduganathan** , Brian Claggett, Brigham and Women's Hosp, Boston, MA; Stephen P Juraschek, BIDMC-Harvard Medical Sch, Auburndale, MA; Scott D Solomon, Brigham and Womens Hosp, Boston, MA

11:05 AM

Q & A

11:10 AM

Cost Effectiveness of Treating Hypertension According to 2017 American College of Cardiology / American Heart Association Hypertension (2017 ACC / AHA) Guidelines

**Joanne M. Penko** , Univ of California, San Francisco, San Francisco, CA; Brandon K. Bellows, Columbia Univ, New York, NY; Gabriel S. Tajeu, Temple Univ, Philadelphia, PA; David Guzman, Pamela G. Coxson, Kirsten Bibbins-Domingo, Univ of California, San Francisco, San Francisco, CA; Andrew E. Moran, Columbia Univ, New York, NY

11:15 AM

Q & A

# Moderated Digital Posters

## EP.MDP43 - Sex- and Racial/Ethnic Differences in Cardiovascular Disease Epidemiology

#### Moderated Posters 7, Science and Technology Hall

### Sunday, November 17, 2019, 10:30 AM - 11:20 AM

10:30 AM

Gender Differences in the Prognostic Impact of Echocardiographic Indices and Bnp Levels in the Community-Based Population

**Takuya Hasegawa** , Natl Cerebal & Cardiovascular Ctr, Suita Osaka, Japan; Masanori Asakura, Hyogo Coll of Med, Hyogo, Japan; Mari Sakamoto, Natl Cardiovascular Ctr, Suita-city,Osaka, Japan; Yasuhiro Hamatani, Natl Cerebral and Cardiovascular Ct, Osaka, Japan; Masashi Amano, Natl Cerebal & Cardiovascular Ctr, Suita Osaka, Japan; Atsushi Okada, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Makoto Amaki, Hiroyuki Takahama, Natl Cerebral and Cardiovascular, Suita, Japan; Hideaki Kanzaki, Natl Cardiovascular Ctr, Osaka, Japan; Satoshi Yasuda, Natl Cereb Cardiovascular Ctr, Osaka, Japan; Chisato Izumi, Natl Cerebral and Cardiovacular, Suita, Japan; Masafumi Kitakaze, Natl Cerebral and Cardiovascular, Suita, Japan

10:35 AM

Q & A

10:40 AM

Echocardiography, Cardiac Biomarkers and Their Inter-Relationships Differ Between Normal Asian and Caucasian Populations

**Anna P Pilbrow** , Univ of Otago Christchurch, Christchurch, New Zealand; Siew Pang Chan, Natl Univ of Singapore, Singapore, Singapore; Chris M Frampton, Univ of Otago Christchurch, Christchurch, New Zealand; Lieng H Ling, Natl Univ of Singapore, Singapore; Richard Troughton, Chris J Pemberton, Univ of Otago Christchurch, Christchurch, New Zealand; Carolyn Lam, Natl Univ of Singapore, Singapore, Singapore; Vicky A Cameron, A Mark Richards, Univ of Otago Christchurch, Christchurch, New Zealand

10:45 AM

Q & A

10:50 AM

Sex Differences in 30-day All-cause Mortality Following Hospitalization for Acute Myocardial Infarction

**Matthew T Mefford** , Bonnie H. Li, Lei Qian, Teresa Nina Harrison, Kaiser Permanente, Pasadena, CA; Ronald D Scott, Kaiser Permanente, Los Angeles, CA; Paul Muntner, Univ Alabama Birmingham, Birmingham, AL; Kristi Reynolds, Kaiser Permanente, Pasadena, CA

10:55 AM

Q & A

11:00 AM

Association of African Ancestry With Arterial Stiffness and Risk of Hypertension: Findings From the Dallas Heart Study

**Ezimamaka Ajufo** , Neela D. Thangada, Colby Ayers, Julia Kozlitina, Univ of Texas Southwestern, Dallas, TX; Wanpen Vongpatanasin, Univ TX Southwestern Med, Dallas, TX; Micheal E. Hall, Univ of Mississippi Medical Ctr, Jackson, MS; Adam P Bress, Univ of Utah, Salt Lake City, UT; Sandeep Das, Mark H Drazner, Amit Khera, James A De Lemos, Ambarish Pandey, Univ of Texas Southwestern, Dallas, TX

11:05 AM

Q & A

11:10 AM

Racial Disparities in Heart Failure Hospitalizations and In-Hospital Mortality in Illinois: 2016-2018

**Leah Rethy** , Joe Feinglass, Lindsay Pool, Thanh-Huyen T Vu, Sadiya S. Khan, Northwestern Univ, Chicago, IL

11:15 AM

Q & A

# Abstract Oral Session

## HY.AOS.329 - Hot Topics in High Blood Pressure Research

#### 108A

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Zorina S Galis, Bethesda, MD

10:45 AM

Moderator

Hongyu Qiu, Atlanta, GA

10:45 AM

Conditional Kidney-Specific Knockout of ADAM17 Causes Arterial Stiffness and Hypertension

**Kai Chen** , Shirley Wang, Zhongjie Sun, Univ of Tennessee HSC, Memphis, TN

10:55 AM

Q & A

11:00 AM

Inhibition of Angiotensin-converting Enzyme Reduces Bactericidal Immunity of Neutrophils

**Zakir Khan** , Jorge Giani, Ellen Bernstein, Cedars-Sinai Medical Ctr, Los Angeles, CA; Luciana C Veiras, Cedars-Sinai Medical Ctr, W Hollywood, CA; Duo-Yao Cao, Suguru Saito, Zhenzi Peng, Derick Okwan, Kenneth E Bernstein, Cedars-Sinai Medical Ctr, Los Angeles, CA

11:10 AM

Q & A

11:15 AM

VEGF-B Cooperates With PlGF to Modulate the Splenic Immune Response Involved in Angiotensin II Induced Hypertension and Target Organ Damage

**Marialuisa Perrotta** , Sapienza Univ of Rome, Rome, Italy; Fabio Pallante, Lorenzo Carnevale, Daniele Iodice, IRCCS Neuromed, Pozzilli, Italy; Sara Perrotta, Giuseppe Lembo, Sapienza Univ of Rome, Rome, Italy; Daniela Carnevale, Sapienza Univ/IRCCS Neuromed, Rome, Italy

11:25 AM

Q & A

11:30 AM

**The Minor Allele of a Single Nucleotide Polymorphism in** SH2B3 **Promotes Hypertension Development in Mice**

**Matthew R Alexander** , Vanderbilt Univ Medical Ctr, Nashville, TN; Bethany L Dale, Charles Smart, Vanderbilt Univ Sch of Med, Nashville, TN; Yuhan Chen, Vanderbilt Univ Medical Ctr, Nashville, TN; Daniel Levy, Natl Insts of Health, Framingham, MA; Meena S Madhur, Vanderbilt Univ Medical Ctr, Nashville, TN

11:40 AM

Q & A

11:55 AM

Q & A

# Abstract Oral Session

## CA.AOS.537 - Stop and Go: Cardiomyocyte Proliferation

#### 120A

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Sangeetha Vadakke-Madathil, New York, NY

10:45 AM

Moderator

Bernhard Kuhn, Pittsburgh, PA

10:45 AM

Exosomal Mir-106a-363 Cluster Enhances Endogenous Myocardial Repair by Stimulating Cardiomyocyte Cell Cycle Re-Entry in the Ischemic Myocardium

**Jihye Jung** , Stanford Cardiovascular Inst, Stanford Sch of Med, Stanford, CA; Yuko Tada, Stanford Univ Sch of Med, Stanford, CA; Daniel von Bornstädt, Stanford Sch of Med, Palo Alto, CA; Siyeon Rhee, Stanford Univ, Stanford, CA; Young-Jun Jeon, Stanford Sch of Med, Stanford, CA; Christine Wahlquist, Stanford Univ, Palo Alto, CA; Anthony C Yu, Stanford Univ, Stanford, CA; Michelle Santoso, Stanford Sch of Med, Stanford, CA; Connor O'Brien, Stanford Cardiovascular Inst, Stanford Sch of Med, Stanford, CA; Kristy Red-Horse, Eric A Appel, Mark Mercola, Stanford Univ, Stanford, CA; Joseph Woo, Stanford Sch of Med, Palo Alto, CA; Phillip C Yang, Stanford Univ, Stanford, CA

10:55 AM

Q & A

11:00 AM

The Long Non-coding RNA MALAT1 is Required for Cardiomyocytes Proliferation and Postnatal Cardiac Regeneration

**Galip S Aslan** , Yosif Manavski, Christina Ott, Cardiovascular Regeneration, Frankfurt, Germany; Stefanie Dimmeler, Cardiovascular Regeneration, Frankfurt Am Main, Germany

11:10 AM

Q & A

11:15 AM

Decreased Expression of Lamin B2 Induces Polyploidization of Cardiomyocyte Nuclei and Induces Cell Cycle Withdrawal

**Lu Han** , Univ of Pittsburgh, Pittsburgh, PA; Sangita Choudhury, Boston Children's Hosp, Boston, MA; Jocelyn D Mich-Basso, Univ of Pittsburgh, Pittsburgh, PA; Balakrishnan Ganapathy, Biogen, Cambridge, MA; Niyatie Ammanamanchi, Univ of Pittsburgh/Rangos Res Ctr, Pittsburgh, PA; Sangita Suresh, Harvard Medical Sch, Boston, MA; Mugdha Khaladkar, Univ of Pennsylvania, Philadelphia, PA; Rene Maehr, Univ of Massachusetts Medical Sch, Worcester, MA; Junhyong Kim, James H. Eberwine, Univ of Pennsylvania, Philadelphia, PA; Yijen L Wu, Univ of Pittsburgh, Pittsburgh, PA; Bernhard Kuhn, Children's Hosp of Pittsburgh, Pittsburgh, PA

11:25 AM

Q & A

11:30 AM

Metabolic Reprogramming Determines Cardiomyocyte Proliferation in Both Neonatal and Adult Mice

**Wei Eric Wang** , Luxun Tang, Liao Qiao, Shuang Qu, Wenbin Fu, Xuewei Xia, Chunyu Zeng, Third Military Medical Univ, Chongqing, China

11:40 AM

Q & A

11:45 AM

Cardiomyocytes Differentiated From Ccnd2 Overexpressing Human Induced Pluripotent Stem Cells Remuscularize the Myocardial Scar in Mice a 6 Month Study

**Chengming Fan** , Univ of Alabama at Birmingham, birmingham, AL; Vladimir G. Fast, Univ of Alabama at Birmingham, Birmingham, AL; Yawen Tang, Meng Zhao, James Turner, Univ of Alabama at Birmingham, birmingham, AL; Wuqiang Zhu, Univ of Alabama, Birmingham, AL; Jianyi ZHANG, Univ of Alabama at Birmingham, Birmingham, AL

11:55 AM

Q & A

# Cardiovascular Seminar

## EP.CVS.568 - AHA's Strategic Goals in 2019 and Beyond (Part 2)

#### 201C

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Norrina B ALLEN, Chicago, IL

10:45 AM

Moderator

Catherine P Benziger, Duluth, MN

11:00 AM

Defining and Monitoring the Health of the US

Gregory Roth, Seattle, WA

11:15 AM

Forming Partnerships to Achieving the Improved Health and Wellbeing

Janet Wright, Baltimore, MD

11:30 AM

Group Discussion

11:50 AM

Group Reports

# Cardiovascular Seminar

## AT.CVS.90 - ATVB and SfRBM Joint Session: Redox Signaling and Cardiovascular Disease

#### 126B

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Chris Kevil, Shreveport, LA

10:45 AM

Moderator

Yabing Chen, Birmingham, AL

10:45 AM

Redox Regulation of Mitochondrial Dynamics and Signaling in AngioGenesis

MASUKO USHIO-FUKAI, Augusta, GA

10:55 AM

Q&A

11:00 AM

microRNAs, Metabolically Healthy Obesity and Atherosclerosis

Xiaofeng Yang, Philadelphia, PA

11:10 AM

Q&A

11:15 AM

Glutathione Regulates the Inflammatory Component of Angiogenesis

Christopher B Pattillo, Shreveport, LA

11:25 AM

Q&A

11:30 AM

Human Platelet Bioenergetics: A Marker and Tool for Mechanism

Sruti Shiva, Pittsburgh, PA

11:40 AM

Q&A

11:45 AM

Flow Signaling in Atherosclerosis

Junichi Abe, Houston, TX

11:55 AM

Q&A

# Cardiovascular Seminar

## VA.CVS.356 - Bench to Bedside: Diabetic Vasculopathy

#### 103B

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Yogendra Kanthi, Ann Arbor, MI

10:45 AM

Moderator

Naomi M Hamburg, Boston, MA

10:45 AM

Basic Science of Diabetic Inflammation and Wound Healing

Katherine Gallagher, MI

10:57 AM

MicroVascular Disease in Diabetic Patients

Joshua A Beckman, Nashville, TN

11:09 AM

Prevention of Diabetic Limb Complications

Teresa Carmen, Cleveland, OH

11:21 AM

How to Salvage the Diabetic Limb

Joe Mills, Houston, TX

11:33 AM

Case Presentation

Arvind Pandey, Brookline, MA

11:45 AM

Panel Discussion

# Cardiovascular Seminar

## LF.CVS.440 - Can We Prescribe a Healthy Old Age?

#### 201AB

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Gerald J Jerome, Towson, MD

10:45 AM

Moderator - Discussant

Eleanor M Simonsick

10:45 AM

Optimal Prevention Approaches Across the Life Course for Promoting Healthy Aging

Norrina B ALLEN, Chicago, IL

10:57 AM

Do Genetics Determine Who Becomes the Wellderly?

Ali Torkamani, La Jolla, CA

11:09 AM

Optimal Aging is Easy: Just Eat This

Alice H Lichtenstein, Boston, MA

11:21 AM

If I Walk Faster Can I Live Forever?

Jennifer Schrack, Baltimore, MD

11:32 AM

Behaviors, Genes and Vascular Biology: What's the Optimal Prescription for Quality Life Years?

Eleanor M Simonsick

11:44 AM

Audience Q&A

# Cardiovascular Seminar

## CE.CVS.456 - Cardiac Fibrosis: Regulation and Roles in the Stressed Heart

#### 120C

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Taben M Hale, Phoenix, AZ

10:45 AM

Moderator

Kedryn Baskin, Irving, TX

10:45 AM

Molecular Mechanisms of Cardiac Fibrosis

Jennifer Davis, Seattle, WA

10:55 AM

Q & A

11:00 AM

Non Coding RNAs in Cardiac Fibrosis

Thierry Pedrazzini, Lausanne

11:10 AM

Q & A

11:15 AM

Neuropeptides in Cardiac Fibrosis

Scott P Levick

11:25 AM

Q & A

11:30 AM

Extracellular Matrix and Inflammation in Cardioprotection

Merry L Lindsey, Jackson, MS

11:40 AM

Q & A

11:45 AM

Thrombospondins and Cardiac Fibrosis

Jeff D Molkentin, Cincinnati, OH

11:55 AM

Q & A

# Cardiovascular Seminar

## HF.CVS.401 - Cast Your Vote! Should This Patient Get a Heart Transplant?

#### 105AB

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Ravi Dhingra, Madison, WI

10:45 AM

Moderator

Prateeti Khazanie, Denver, CO

10:50 AM

Panel Discussion

11:00 AM

Vote & Final Thoughts on Case

11:03 AM

Marijuana Edibles and E-cigarettes: Is Transplant an Option?

Robert Lee Page II, Aurora, CO

11:08 AM

Panel Discussion

11:18 AM

Vote & Final Thoughts on Case

11:22 AM

The Donor Has Hepatitis C: Take it or Let it Go?

Rhondalyn Forde-McLean, Philadelphia, PA

11:27 AM

Panel Discussion

11:37 AM

Vote & Final Thoughts on Case

11:41 AM

Patient is on ECMO: Status 1 or MCS?

Michelle M Kittleson, Los Angeles, CA

11:46 AM

Panel Discussion

11:56 AM

Vote & Final Thoughts on Case

# Cardiovascular Seminar

## AT.CVS.517 - Cellular Lipids and Circulating Lipoproteins in Atherosclerosis

#### 118A

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Marit Westerterp, Groningen

10:45 AM

Moderator

Kerry-anne Rye, Sydney, Australia

10:45 AM

Oxidized Phospholipids in Atherosclerosis

Christoph J Binder, Vienna, Austria

10:55 AM

Q&A

11:10 AM

Q&A

11:15 AM

Smooth Muscle Foam Cells: Non-Professional Macrophages Holding Cholesterol in the Artery Wall

Gordon Francis, Vancouver, BC, Canada

11:25 AM

Q&A

11:30 AM

HDL Biogenesis: Novel Pathway

Sasha A Singh, Boston, MA

11:40 AM

Q&A

11:45 AM

Plasminogen, Lp(a) and ABCA1 Interaction in Atherosclerosis

Nathalie Pamir, Portland, OR

11:55 AM

Q&A

# Cardiovascular Seminar

## VA.CVS.330 - Clash of the Thrombosis Titans: Clinical Controversies in Venous Thromboembolism

#### 103C

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Brett Carroll, Boston, MA

10:45 AM

Moderator

Umberto Campia, Boston, MA

10:45 AM

DOACs Should Be First Line for Treatment of VTE in Cancer

Jean Connors, Boston, MA

10:53 AM

DOACs Should NOT Be First Line for Treatment of VTE in Cancer

Gary Raskob, Oklahoma City, OK

11:01 AM

VTE Prophylaxis Should Be Given to Most Cancer Patients Receiving Chemotherapy

Alok Khorana, Cleveland, OH

11:09 AM

VTE Prophylaxis Should NOT Be Given to Most Cancer Patients Receiving Chemotherapy

rachel rosovsky, Waban, MA

11:17 AM

Patients With Provoked VTE and Persistent Risk Factor Should Get Extended Anticoagulation

Samuel Z Goldhaber, Boston, MA

11:25 AM

Patients With Provoked VTE and Persistent Risk Factor Should NOT Get Extended Anticoagulation

Teresa Carmen, Cleveland, OH

11:33 AM

The Guidelines Are Wrong: High Risk Medical Patients Should Receive Extended VTE Prophylaxis

Alex C Spyropoulos, NY, NY

11:49 AM

Panel Discussion

# Cardiovascular Seminar

## CH.CVS.451 - Emerging Perspectives on Referral for Advanced Cardiac Therapies and Transplantation

#### 111AB

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Jennifer A Su, Los Angeles, CA

10:45 AM

Moderator

Lindsay May, Salt Lake City, UT

10:45 AM

When to Refer, When to Transplant: Late Stage Fontan and Other Complex CHD

Kimberly Y Lin, Swarthmore, PA

11:00 AM

Impact of recent Changes in Pediatric and Adult Heart Transplant Listing Criteria

Ryan Davies, Dallas, TX

11:15 AM

Challenging the Status Quo in Transplant Candidacy re: Syndromes and Other Systemic Diseases

Justin Godown, Nashville, TN

11:30 AM

Contemporary Pediatric and ACHD VAD Practice and Outcomes: Borrowing From the Adults and Making Up the Rest on the Fly

Angela Lorts, Cincinnati, OH

11:45 AM

Myocardial Recovery in Pediatrics: Mirage or a Ripe Opportunity

Emma J Birks, Louisville, KY

# Cardiovascular Seminar

## QU.CVS.503 - I Googled Your Report Card: Is Public Reporting of Physician and Hospital Performance Good for Patients?

#### 202AB

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Brahmajee K Nallamothu, Ann Arbor, MI

10:45 AM

Moderator

Karen Joynt Maddox, Saint Louis, MO

10:45 AM

Clinician and Hospital Report Cards: Introduction to the Session

Karen Joynt Maddox, Saint Louis, MO

10:57 AM

Historical Perspective on Public Reporting of Cardiovascular Outcomes

Robert W Yeh, Boston, MA

11:09 AM

How Public Reporting Influences Clinician Behavior

Daniel M Blumenthal, Cambridge, MA

11:21 AM

Statistical and MethoDological Issues In Measuring Clinician and Hospital Performance

Sharon-lise Normand, Boston, MA

11:33 AM

UnintEnded Consequences in Public Reporting of Clinical Performance

Rachel M. Werner, Philadelphia, PA

11:45 AM

Panel Participant

Daniel M Blumenthal, Cambridge, MA

11:45 AM

Panel Participant

Sharon-lise Normand, Boston, MA

11:45 AM

Panel Participant

Rachel M. Werner, Philadelphia, PA

11:45 AM

Panel Discussion

# Cardiovascular Seminar

## IM.CVS.393 - Infiltrative Heart Disease: Evaluation, Treatment, and Imaging Insights

#### 108B

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Melissa Daubert, Durham, NC

10:45 AM

Moderator

Selma Mohammed, Rochester, MN

10:45 AM

Overview of Infiltrative Heart Disease

Sharmila Dorbala, Boston, MA

10:56 AM

Diagnostic Evaluation: Echocardiography

Sanjiv J Shah, Chicago, IL

11:07 AM

Diagnostic Evaluation: Nuclear Imaging

Paco Bravo, Miami, FL

11:18 AM

Diagnostic Evaluation: Cardiac MRI

Karen G Ordovas, San Francisco, CA

11:29 AM

Case Examples and Treatment

Mario J Garcia, Bronx, NY

11:40 AM

Case Examples and Treatment 2 - Chagas Disease

Carlos Eduardo Rochitte, Sao Paulo, Brazil

11:51 AM

Panel Discussion

# Cardiovascular Seminar

## IN.CVS.388 - Interesting Cases from the Cath Lab

#### 107AB

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Peter James Mason, Milwaukee, WI

10:45 AM

Moderator

KELLY EPPS, Washington, DC

10:45 AM

Panel Participant

Jacqueline E Tamis-Holland, New York, NY

10:45 AM

Panel Participant

Gregory DUCROCQ, Paris, France

10:45 AM

Panel Participant

Hani Jneid, Houston, TX

10:45 AM

Challenging Coronary Interventional Cases

Islam Y Elgendy, Boston, MA

11:00 AM

Discussion

11:10 AM

Challenging Structural Interventional Cases

KELLY EPPS, Washington, DC

11:25 AM

Discussion

11:35 AM

Challenging Peripheral Interventional Cases

William S Jones, Durham, NC

11:50 AM

Discussion

# Cardiovascular Seminar

## AC.CVS.233 - Ischemia-Reperfusion Injury: Novel Drugs Open a Window to the Future!

#### 103A

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Gerd Heusch, Essen, Germany

10:45 AM

Moderator

Robert A Kloner, Los Angeles, CA

10:45 AM

102 About Ischemia Reperfusion Injury: Pathophysiological Mechanism and Methods for Evaluation

Yochai Birnbaum, Houston, TX

11:00 AM

Drugs to Amerliorate Myocardial Ischemia-reperfusion: Our Experience So Far!

Michel Ovize, Lyon, France

11:15 AM

New Strategies on the Horizon: SGLT2 Inhibitors and Sphingosine-1-phosphate

Carlos Santos-Gallego, New York City, NY

11:30 AM

Metabolic Control of Ischaemia Reperfusion Injury

Gemma Vilahur, Barcelona, Spain

# Cardiovascular Seminar

## CM.CVS.436 - Meet the Experts in Cardiometabolic Science - Opportunities for Networking and Career Development

#### Terrace Ballroom IV

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Prakash C Deedwania, Fresno, CA

10:45 AM

Invited Presenter

Darren K. K McGuire, Dallas, TX

10:48 AM

Invited Presenter

Peter Wilson, Atlanta, GA

10:51 AM

Invited Presenter

Christie M Ballantyne, Houston, TX

10:54 AM

Invited Presenter

Neha Pagidipati, Durham, NC

10:57 AM

Invited Presenter

Sherita H Golden, Baltimore, MD

11:00 AM

Invited Presenter

Manisha Chandalia, Kemah, TX

11:03 AM

Networking and Discussion

# Cardiovascular Seminar

## CH.CVS.441 - My Favorite Mistake: Learning from Unexpected Adverse Outcomes

#### 112AB

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Catherine D Krawczeski, Columbus, OH

10:45 AM

Moderator

Jessica Colyer, Washington, DC

10:45 AM

My Worst Cath Lab Experience - So Others Can Learn

Jonathan Rome, Philadelphia, PA

11:00 AM

My Worst EP Lab Experience - So Others can Learn

Thomas Kriebel, Kaiserslautern

11:15 AM

My Worse CICU Experience - So Others Can Learn

Mjaye L Mazwi, Toronto, ON, Canada

11:30 AM

My Worst Echo Miss - So Others Can Learn

Leo Lopez, Miami, FL

11:45 AM

My Worst OR Experience - So Others Can Learn

Richard G Ohye, Ann Arbor, MI

# Cardiovascular Seminar

## SA.CVS.473 - New Concepts in Ischemic Heart Disease

#### 109AB

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

J. Daniel D Muehlschlegel, Boston, MA

10:45 AM

Moderator

SANFORD ZEIGLER, Charleston, SC

10:45 AM

Impact of Gender in Ischemic Heart Disease

Eugenia Gianos, New York, NY

11:00 AM

Preoperative Support of the Failing Ischemic Heart

William Hiesinger, Stanford, CA

11:15 AM

Protecting the Kidneys After CABG; What Does the Evidence Say?

Amanda Fox, Dallas, TX

11:30 AM

Who Benefits From Hybrid Revascularization vs. PCI Alone

Pavan Atluri, Philadelphia, PA

11:45 AM

Minimally Invasive Approaches to CABG Surgery

Marc RUEL, Ottawa, ON, Canada

# Cardiovascular Seminar

## PR.CVS.176 - Omega-3 Fatty Acids, EPA and CVD Risk: No Longer a Fish Tale?

#### 204C

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Michael Miller, Baltimore, MD

10:45 AM

Moderator

Francine K Welty, Brookline, MA

10:45 AM

Overview of Omega-3 Fatty Acids and Cardiovascular Outcomes

Michael Miller, Baltimore, MD

11:00 AM

Potential Beneficial Mechanisms of Omega-3 Fatty Acids

R Mason, Boston, MA

11:15 AM

Benefits of Omega-3 Fatty Acids Beyond Cardiovascular Effects

Abdulhamied Alfaddagh, Baltimore, MD

11:30 AM

Case Presentation for: Omega-3 Fatty Acids and Other Lipid-Lowering Therapies: What Order and When?

Abdulhamied Alfaddagh, Boston, MA

11:45 AM

Omega-3 Fatty Acid and Other Lipid-Lowering Therapies: What Order and When?

Terry A Jacobson, Atlanta, GA

# Cardiovascular Seminar

## WS.CVS.81 - Populations with Unique Cardiovascular Risk

#### 117

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Jorge R Kizer

10:45 AM

Moderator

Tochi Okwuosa, Chicago, IL

10:45 AM

HIV and Cardiovascular Disease

Matthew J Feinstein, Chicago, IL

10:57 AM

Discussion

11:03 AM

Sleep Disorders and Cardiovascular Disease

Virend K Somers, Rochester, MN

11:15 AM

Discussion

11:21 AM

Depression and Cardiovascular Disease

Viola Vaccarino, Atlanta, GA

11:33 AM

Discussion

11:45 AM

Oral Health and Cardiovascular Disease

Hatice Hasturk, Boston, MA

11:51 AM

Discussion

# Cardiovascular Seminar

## AT.CVS.284 - Pulmonary Arterial Hypertension and Infectious Diseases: A Global Health Issue

#### 126A

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Vinicio de Jesus Perez, Palo Alto, CA

10:45 AM

Moderator

Magdi Yacoub, London, United Kingdom

10:45 AM

Spectrum of Infectious Etiologies of Pulmonary Vascular Diseases

Ghazwan Butrous, Canterbury, United Kingdom

10:55 AM

Q&A

10:57 AM

Schistosomiasis: The Most Common Global Etiology of Pulmonary Vascular Diseases

Rahul Kumar, Denver, CO

11:07 AM

Q&A

11:09 AM

HIV, Drug Abuse and Pulmonary Arterial Hypertension: A Growing Epidemic

Navneet Dhillon, Kansas City, KS

11:19 AM

Q&A

11:21 AM

Pulmonary Arterial Hypertension and Infectious Diseases in Africa

Anna Mocumbi, Maputo, Mozambique

11:31 AM

Q&A

11:33 AM

Novel Therapeutic Strategies for the Treatment of Pulmonary Hypertension Secondary to Infectious Diseases

Ralph T Schermuly, Giessen

11:43 AM

Q&A

11:55 AM

Q&A

# Cardiovascular Seminar

## EA.CVS.389 - Rapid Fire: Hearts Prone to Misfire: Management of Arrhythmias in Challenging Cardiomyopathies

#### 113A

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Anne B Curtis, Buffalo, NY

10:45 AM

Moderator

jodie l hurwitz, dallas, TX

10:45 AM

Case Presentation

Cesia Gallegos, New Haven, CT

10:48 AM

Sarcoidosis - Emerging Concepts and New Strategies for Arrhythmia Management

Lynda E ROSENFELD, New Haven, CT

10:58 AM

Q&A

11:03 AM

Cardiac Amyloidosis and Arrhythmias: More Common and Less Lethal Than You Thought

Jordana Kron, Richmond, VA

11:13 AM

Q&A

11:18 AM

Arrhythmogenic RV Cardiomyopathy: Evolving Concepts and Consensus

Harikrishna S Tandri, Baltimore, MD

11:28 AM

Q&A

11:33 AM

Hypertrophic Cardiomyopathy: Controversies in Risk Stratification and Management

Francesco Pelliccia, Rome, Italy

11:43 AM

Q&A

11:48 AM

Arrhythmia-Induced Cardiomyopathy: When Arrhythmias and Heart Failure Coexist, is it the Chicken or the Egg?

jian-ming Li, Minneapolis, MN

11:58 AM

Q&A

# Cardiovascular Seminar

## ST.CVS.410 - Superwoman Syndrome: Racial/Ethnic Disparities in Cardiovascular Disease in Minority Women

#### 102AB

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Trudy R Gaillard, Miami, FL

10:45 AM

Moderator

Gayenell S Magwood, Charleston, SC

10:45 AM

Cardiovascular Risk and Outcomes in Minority Women

Mercedes R Carnethon, Chicago, IL

11:00 AM

Cardiovascular Prevention Strategies for Minority Women

Cheryl D Bushnell, Winston Salem, NC

11:15 AM

The Biology of Adversity

Michelle A Albert, San Francisco, CA

11:30 AM

Caregiving Among Minority Women

Barbara J Lutz, Hampstead, NC

11:45 AM

Discussion

# Cardiovascular Seminar

## DD.CVS.18 - What Are We Doing About Rare Cardiovascular Diseases?

#### 120B

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

John Travis Hinson, West Hartford, CT

10:45 AM

Moderator

Victoria Parikh, Stanford, CA

10:45 AM

iPS Cells for Rare Disease Drug Discovery

Maria Kontaridis, Boston, MA

10:55 AM

Q & A

11:00 AM

Update on Danon Disease

Eric D Adler, La Jolla, CA

11:10 AM

Q & A

11:15 AM

Rare Cardiac Disorder Registries

Ray Hershberger, Columbus, OH

11:25 AM

Q & A

11:30 AM

Update on RBM20 Cardiomyopathy

Victoria Parikh, Palo Alto, CA

11:40 AM

Q & A

11:45 AM

BAG3 Mutation Cardiomyopathy

Michael Hesse, Bonn, Germany

11:55 AM

Q & A

# Early Career

## EA.EC.272 - AHA Early Career Session - Welcome to the World of EP

#### 113BC

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Richard Page, Burlington, VT

10:45 AM

Moderator

Miguel Leal, Madison, WI

10:45 AM

A Changing Specialty - Where is EP Going and How Do I Stay Relevant in an Evolving Field?

Charles Henrikson, Portland, OR

11:00 AM

Will I Have a Job? What Are the Trends in Physician Demand / Supply in the EP Community

Usha Tedrow, Boston, MA

11:15 AM

Time Management - How to Keep the Work Day Sane

Kristen K Patton, Seattle, WA

11:30 AM

Do I Have to Choose Between Clinical or Scholarly Productivity?

Michael R Gold, Charleston, SC

11:45 AM

Panel Discussion

# Early Career

## GE.EC.318 - Single-Cell RNA Sequencing Boot Camp

#### 121C

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Jennie J Lin, Chicago, IL

10:45 AM

Moderator

Nathan R Tucker, Boston, MA

10:45 AM

Single-Cell Sequencing - Intoduction to Analysis

Jennie Lin, Chicago, IL

10:55 AM

Q&A

11:00 AM

Single-Cell Sequencing - Revolutionary Technology in Basic and Translational Science

Nathan R Tucker, Boston, MA

11:10 AM

Q&A

11:15 AM

Single-Cell Sequencing - Overview

Nabila Bouatia-Naji, Paris, France

11:25 AM

Q&A

11:30 AM

Initiation to Data Visualization of Cell Clusters (1)

Konstantinos Stellos, Newcastle Upon Tyne

11:40 AM

Q&A

11:45 AM

Initiation to Data Visualization of Cell Clusters (2)

Niels Voigt, Göttingen

11:55 AM

Q&A

# Early Career

## CE.EC.311 - Tales from the Transition: How to Differentiate Yourself from the Pack

#### 119AB

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

moderator

Karim Sallam, Stanford, CA

10:45 AM

Moderator

Jitka A Virag, Greenville, NC

10:45 AM

Tales From the Transition: How to Differentiate Yourself as a New PI

Jennifer Kwong, Atlanta, GA

11:00 AM

Tales From the Transition: How to Differentiate Yourself From the Pack

Prasanth Puthanveetil, Downers Grove, IL

11:15 AM

Tales From the Transition: How to Differentiate Yourself With Your K99

Xi Fang, La Jolla, CA

11:30 AM

Tales From the Transition: How to Differentiate Yourself From the Pack: A Mentor's Perspective

Emelia Benjamin, Framingham, MA

11:45 AM

Panel Discussion

# Hall

## EP.HT.02 - TED Style Talks - The Future of EP: Science and Math in Arrhythmia Innovation 1

#### EP Central

### Sunday, November 17, 2019, 10:45 AM - 11:30 AM

10:45 AM

Moderator

N A Estes III, Pittsburgh, PA

10:56 AM

Math and the Heart

Natalia Trayanova, Baltimore, MD

11:08 AM

Molecules and the Heart

Christine M Albert, W Hollywood, CA

11:19 AM

Genes and the Heart

Patrick T Ellinor, Boston, MA

# Joint Sessions

## HF.JS.1615 - Global Roundtable: Addressing Questions Regarding Devices and Heart Failure (ANMCO Italian Association of Hospital Cardiologists, Cardio Renal Society of America, Gulf Heart Association, Pan African Society of Cardiology and Singapore Cardiac Society)

#### 121A

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Hector O Ventura, New Orleans, LA

10:45 AM

Device Therapies in Patients with Heart Failure and Chronic Kidney Disease

Peter A McCullough, Dallas, TX

10:57 AM

The Pulmonary Artery Catheter in Shock

Mohamed Jeilan, Leicester, United Kingdom

11:09 AM

Percutaneous Mitral Valve Repair: Clip away?

Stefano Urbinati, Italy

11:21 AM

Challenges and Opportunities in Establishing Advanced HF Programs in the Middle East

Feras Bader, Abu Dhabi, United Arab Emirates

11:33 AM

Artificial Intelligence in ECG-Based Potassium Measurement

John Dillon, Rochester, MN

11:45 AM

Panel Discussion

# Late-Breaking Science

## LBS.05 - Late Breaking Science V: Challenges in Heart Failure Management

#### Main Event I

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Ileana L Pina, Cleveland Hghts, OH

10:45 AM

Moderator

Mary Norine Walsh, Indianapolis, IN

10:45 AM

Social Media Moderator

Mark H Drazner, Dallas, TX

10:45 AM

Results From the Pediatric Heart Network's Fontan Udenafil Exercise Longitudinal Trial

**David J Goldberg** , Children's Hosp of Philadelphia, Philadelphia, PA; Victor Zak, New England Res Insts, Watertown, MA; Bryan H Goldstein, Cincinnati Children's Hosp, Cincinnati, OH; Kurt Schumacher, Univ of Michigan, Ann Arbor, MI; Jonathan Rhodes, Children's Hosp Boston, Boston, MA; Daniel J Penny, Texas Children's Hosp / Baylor Coll of Med, Houston, TX; Christopher J Petit, Emory Univ Sch of Med, Atlanta, GA; Salil Ginde, Children's Hosp of Wisconsin, Milwaukee, WI; Shaji C Menon, Univ of Utah, Salt Lake City, UT; Seong-Ho Kim, Sejong General Hosp, Bucheon-si, Korea, Republic of; Gi Beom Kim, Seoul Nat Univ Children's Hosp, Seoul, Korea, Republic of; Todd T Nowlen, Phoenix Children's Hosp, Phoenix, AZ; Michael V DiMaria, Children's Hosp Colorado, Aurora, CO; Benjamin P Frischhertz, Vanderbilt Univ Sch of Med, Nashville, TN; Jonathan B Wagner, Children's Mercy Heart Ctr, Kansas City, MO; Kimberly E McHugh, Medical Univ of South Carolina, Charleston, SC; Brian W McCrindle, Hosp for Sick Children, Toronto, ON, Canada; Amanda J Shillingford, A.I. DuPont Hosp for Children, Wilmington, DE; Arash A Sabati, Los Angeles Children's Hosp, Los Angeles, CA; Anji T Yetman, Childrens Hosp and Medical Ctr, Omaha, NE; Anitha S John, Children's Natl Medical Ctr, Washington, DC; Marc E Richmond, Columbia Univ, New York, NY; Matthew D Files, Seattle Children's Hosp, Seattle, WA; R Mark Payne, Indiana Univ. Sch of Med, Indianapolis, IN; Andrew S Mackie, Stollery Children's Hosp, Edmonton, AB, Canada; Christopher K Davis, Rady Children's Hosp, San Diego, CA; Shabana Shahanavaz, St. Louis Children's Hosp, Saint Louis, MO; Kevin D Hill, Duke Children's Pediatric and Congenital Heart Ctr, Durham, NC; Ruchira Garg, Cedars-Sinai Medical Ctr, Los Angeles, CA; Jeffrey P Jacobs, Johns Hopkins All Children's Hosp, St Petersburg, FL; Michelle S Hamstra, Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; Stacy Woyciechowski, The Children's Hosp of Philadelphia, Philadelphia, PA; Kathleen A Rathge, Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; Michael G McBride, Children's Hosp of Philadelphia, Philadelphia, PA; Peter C Frommelt, Medical Coll of Wisconsin, Milwaukee, WI; Mark W Russell, Univ of Michigan, Ann Arbor, MI; Elaine M Urbina, Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; James Yeager, Mezzion, Deerfield, IL; Victoria L Pemberton, NHLBI, Bethesda, MD; Mario P Stylianou, Natl Insts of Health, Bethesda, MD; Gail D Pearson, NHLBI NIH, Bethesda, MD; Stephen Paridon, Children's Hosp, Philadelphia, PA; Investigators of the FUEL Writing Committee / Pediatric Heart Network

10:54 AM

Discussant

Craig A SABLE, Potomac, MD

10:58 AM

Effect of Treatment According to Age in the Dapagliflozin and Prevention of Adverse-Outcomes in Heart Failure Trial (DAPA-HF)

**Felipe Martinez** , Insto Damic, Cordoba, Argentina; David L DeMets, Univ of Wisconsin, Madison, WI; Silvio E Inzucchi, Yale Univ Sch of Med, New Haven, CT; Lars Kober, Rigshospitalet, Copenhagen, Denmark; Mikhail N Kosiborod, St. Luke's Health System, Kansas City, MO; Anna Maria langkilde, Olof Bengtsson, AstraZenca, Gothenburg, Sweden; Piotr Ponikowski, Medical Univ, Wroclaw, Poland; Marc S Sabatine, TIMI Study Group, Boston, MA; Mikaela Sjostrand, AstraZenca, Gothenburg, Sweden; Scott Solomon, Brigham and Women's Hosp, Boston, MA; John J McMurray, BHF Cardiovascular Res Ctr, Glasgow, United Kingdom

11:07 AM

Effect of Treatment on the Kansas City Cardiomyopathy Questionnaire (KCCQ) in the Dapagliflozin and Prevention of Adverse-Outcomes in Heart Failure Trial (DAPA-HF)

Mikhail N Kosiborod, St. Luke's Health System, Kansas City, MO; David L DeMets, Univ of Wisconsin, Madison, WI; Silvio E Inzucchi, Yale Univ Sch of Med, New Haven, CT; Lars Kober, Rigshospitalet, Copenhagen, Denmark; Anna Maria langkilde, Olof Bengtsson, AstraZenca, Gothenburg, Sweden; Felipe Martinez, Insto Damic, Cordoba, Argentina; Piotr Ponikowski, Medical Univ, Wroclaw, Poland; Marc S Sabatine, TIMI Study Group, Boston, MA; Mikaela Sjostrand, AstraZenca, Gothenburg, Sweden; Scott Solomon, Brigham and Women's Hosp, Boston, MA; **John J McMurray** , BHF Cardiovascular Res Ctr, Glasgow, United Kingdom

11:13 AM

Discussant

Carolyn Lam, Singapore

11:17 AM

LBCT: Effects of Sacubitril/Valsartan in Women Compared to Men With Heart Failure and Preserved Ejection Fraction

**John J McMurray** , Univ of Glasgow, Glasgow, United Kingdom; Carolyn S. P. Lam, Natl Heart Ctr Singapore & Duke-Natl Univ of Singapore, Singapore, Malaysia; Martina McGrath, Brigham and Women's Hosp, Boston, MA; Jhund Pardeep S, Univ of Glasgow, Glasgow, United Kingdom; Eileen O'Meara, Montreal Heart Inst, Montreal, QC, Canada; Milton Packer Jr., Baylor Heart and Vascular Inst, Dallas, TX; Margaret M Redfield, Mayo Clinic, Rochester, MN; Victor Shi, Novartis Pharmaceutical Corp, East Hanover, NJ; Nancy K Sweitzer, Univ of Arizona, Tucson, AZ; Scott D Solomon, Brigham and Women's Hosp, Boston, MA

11:26 AM

Effect of Sacubitril/Valsartan Across the Spectrum of Ejection Fraction in Heart Failure

**Scott D Solomon** , Brigham and Women's Hosp, Boston, MA; Lars Lund, Sweden; Milton Packer, Baylor Scott & White Heart and Vascular Hosp, Dallas, TX; Jean L. Rouleau, Toronto General Hosp, Toronto, ON, Canada; Michael R Zile, Medical Univ of South Carolina, Charleston, SC; Karl B Swedberg, Sahlgrenska Univ Hosp Ostra, Goteborg, Sweden; Nancy K Sweitzer, Univ of Arizona, Tucson, AZ; Akshay S Desai, Brigham Women's Hosp, Boston, MA; Lars Kober, Rigshospitalet, Copenhagen; Marty Lefkowitz, Novartis Pharmaceuticals Corp, East Hanover, NJ; Gerard C Linssen, Hosp Group Twente, Almelo, LA; Inder S Anand, VA San Diego Healthcare System, La Jolla, CA; John J McMurray, BHF Cardiovascular Res Ctr, Glasgow, United Kingdom

11:35 AM

Discussant

Lynne Warner Stevenson, Nashville, TN

11:39 AM

Putting It All Together: How to Use SGLT2 Inhibitors and ARNIs in Practice

Clyde W Yancy Jr., Chicago, IL

11:49 AM

Discussion

# Main Event

## VA.ME.341 - A Sign of the Times for PAD: Stents, Drugs and Walk 'n' Roll

#### Main Event II

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Geoffrey Barnes, Ann Arbor, MI

10:45 AM

Antithrombotic Therapy for PAD - From Mechanism to Implementation

Sonia Anand, Hamilton, ON, Canada

10:56 AM

Metabolic Therapies for PAD: A Focus on Lipids and Diabetes

Marc P Bonaca

11:07 AM

Personalizing Exercise Therapy for PAD

Mary M McDermott, Chicago, IL

11:18 AM

Case Presentation: Claudicant

Anna Boniakowski, Ann Arbor, MI

11:29 AM

Intervention Should Be First Line Therapy for Dlaudication

Christopher White, New Orleans, LA

11:40 AM

Medical Therapy Should Be First Line Therapy for Claudication

Joshua A Beckman, Nashville, TN

11:51 AM

Panel Discussion

# Main Event

## IN.ME.1761 - Aspirin: Who Needs it Anymore?

#### Nutter Theatre

### Sunday, November 17, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Michelle L Odonoghue, Boston, MA

10:45 AM

Moderator

Freek W Verheugt, Amsterdam, Netherlands

10:45 AM

Recent Data in Secondary Prevention and Post-PCI: The TWILIGHT of Aspirin Therapy?

Roxana Mehran, New York, NY

11:00 AM

Recent Data and Recommendations for Primary Prevention of ASCVD

Erin D Michos, Baltimore, MD

11:15 AM

Should We Ever Use Aspirin in Atrial Fibrillation?

Freek W Verheugt, Amsterdam, Netherlands

11:45 AM

Panel Discussion

# Early Career Events

## EC.01 - Lunch with Legend

#### Philadelphia Marriott Downtown, Salon F

### Sunday, November 17, 2019, 11:00 AM - 12:30 PM

This is not a CME/CE certified session

# FIT Event

## FIT.18 - Insights from the Council on Lifestyle and Cardiometabolic Health: A Discussion about Lifestyle and Health Disparities

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Sunday, November 17, 2019, 11:00 AM - 11:45 AM

11:00 AM

Moderated by Leanna Ross, PhD; Lilian Sattler, PhD, RPh Panel Participants include Cheryl Anderson, PhD; Mercedes Carnethon, PhD; William Kraus, MD

This is not a CME/CE certified session

# FIT Event

## FIT.20 - Lifestyle Early Career - Fit Lounge Program

#### Pennsylvania Convention Center, 2nd Floor, Heart Hub, Booth 13

### Sunday, November 17, 2019, 11:00 AM - 11:45 AM

This is not a CME/CE certified session

# Hall

## EA.HT.591 - Circulation: Arrhythmia & Electrophysiology - Article Highlights and How to Get Published

#### 204AB

### Sunday, November 17, 2019, 11:00 AM - 12:00 PM

11:00 AM

Moderator

Paul J Wang, Palo Alto, CA

11:00 AM

Moderator

Mark Estes III, Boston, MA

11:00 AM

The Best of the Best Articles This Year

Paul J Wang, Palo Alto, CA

11:08 AM

Tips on How to Get Published

Marco Perez, Stanford, CA

11:16 AM

Panel Participant

Anne M Gillis, Calgary, AB, Canada

11:24 AM

Panel Participant

Mina K CHUNG, Cleveland, OH

11:32 AM

Panel Participant

Glenn FISHMAN, New York, NY

11:40 AM

Panel Participant

Nitish Badhwar, Burlingame, CA

# Simulation

## SIM.10 - Interactive Digital iWall Experiential Learning

#### Simulation Zone - Heart Hub, Hall C

### Sunday, November 17, 2019, 11:00 AM - 12:00 PM

11:00 AM

Invited Presenter

Tina Baykaner, Palo Alto, CA

# Abstract Rapid Fire Oral

## CA.RFO18 - Cardiac Development: Everything Your Parents Never Told You

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 11:35 AM - 12:25 PM

11:35 AM

Moderator

Katherine Yutzey, Cincinnati, OH

11:35 AM

**Human Induced Pluripotent Stem Cells Model** Gata6 **-associated Congenital Heart Disease**

**Arun Sharma** , Harvard Medical Sch, Boston, MA; Lauren Wasson, Harvard Medical Sch, Boston; Jon Willcox, Harvard Medical Sch, Boston, MA; Sarah Morton, Boston Children's Hosp, Boston, MA; Joshua Gorham, Harvard Medical Sch, Boston, MA; Daniel DeLaughter, VanderbiltUniv Medical Ctr, Nashville, TN; Meraj Neyazi, Manuel Schmid, Radhika Agarwal, Min Young Jang, Christopher Toepfer, Tarsha Ward, Harvard Medical Sch, Boston, MA; Yuri Kim, Massachusetts General Hosp, Boston, MA; Alexandre Pereira, Heart Inst (incor), Sao Paulo, Brazil; Steven DePalma, Angela Tai, Seongwon Kim, David Conner, Harvard Medical Sch, Boston, MA; Daniel Bernstein, Stanford Univ, Palo Alto, CA; Bruce Gelb, ICAHN Sch Med, New York, NY; Wendy Chung, Columbia Univ, New York, NY; Elizabeth Goldmuntz, Childrens Hosp Philadelphia, Philadelphia, PA; George Porter, Univ Rochester Medical Ctr, Rochester, NY; Martin Tristani-firouzi, Primary Childrens Univ of Utah, Salt Lake City, UT; Deepak Srivastava, Gladstone Insts, San Francisco, CA; Jonathan Seidman, Christine Seidman, Harvard Medical Sch, Boston, MA

11:40 AM

Q & A

11:45 AM

Glypican-6 is Identified as a Gene Responsible for Sporadic, Non-syndromic Tetralogy of Fallot Cases

**Gennadiy Tenin** , Bernard Keavney, Univ of Manchester, Manchester, United Kingdom

11:50 AM

Q & A

11:55 AM

Novel Insights Into Cardiac Developmental Regulation by Epigenetic Histone Modifying Factors in Multiple Species

**Rwik Sen** , Elizabeth A. Geiger, Tamim H. Shaikh, Univ of Colorado Anschutz Medical Campus, Aurora, CO; Kristin B. Artinger, Univ of Colorado, Aurora, CO

12:00 PM

Q & A

12:05 PM

Cytoglobin Regulates Cilia Length, Function and Organ System Laterality During Development

Elizabeth R Rochon, Jianmin Xue, Manush Saydmohammed, Cecilia W Lo, Michael Tsang, Mark T Gladwin, **Paola Corti** , Univ of Pittsburgh, Pittsburgh, PA

12:10 PM

Q & A

12:15 PM

Neddylation Is Essential For Early Embyonic Cardiogenesis And Cardiomyocyte Maturation

**Rodney Eric Littlejohn** , Augusta Univ, Augusta, GA

12:20 PM

Q & A

# Abstract Rapid Fire Oral

## NR.RFO24 - Downstream Effects of Social Determinants of Health

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 11:35 AM - 12:25 PM

11:35 AM

Moderator

Catherine J Ryan, Chicago, IL

11:35 AM

Ethnic Discrimination is Associated With Depressive Symptoms in Hispanic Adults at Risk for Cardiovascular Disease

**Kaitlin Voigts** , Gia Mudd-martin, Univ of Kentucky, Lexington, KY

11:45 AM

Examining Racial/Ethnic Differences in Cardiovascular Risk Among Women With Breast Cancer

**Shazia A Mitha** , Billy A Caceres, Maxim Topaz, Arlene Smaldone, Columbia Univ Sch of Nursing, New York, NY

11:55 AM

Reaching The Hard-to-reach: Outcomes Of The Severe Hypertension Outreach Intervention

Holly Biola, Jennifer Deyo, Hayes Tiffany, Linda Small, Joan Chaplin, Lynn Fitzgerald, Lincoln Community Health Ctr, Durham, NC; Ezra Pak-Harvey, Thomas M. Granger, Duke Univ, Kannapolis, NC; Carolyn Crowder, Bina Patel, Tracy Stillwell, Howard Eisenson, Lincoln Community Health Ctr, Durham, NC; **Bradi B. Granger** , Duke Univ Sch of Nursing, Durham, NC

12:05 PM

Differences Between Women's And Men's Patterns of Revisits in a Cardiac Emergency Department

**Sylvie Cossette** , Marc-André Maheu-Cadotte, Montreal Heart Inst/UdeM, Montreal, QC, Canada; Tanya Mailhot, Inst de Cardiologie de Montreal, Montreal, QC, Canada; Patrick Lavoie, Montreal Heart Inst/UdeM, Montreal, QC, Canada; Guillaume Fontaine, Montreal Heart Inst, Montreal, QC, Canada; Alexis Cournoyer, Montreal Heart Inst/UdeM/Hôpital Sacré-Coeur/Hôpital Maisonneuve-Rosemont, Montreal, QC, Canada; Alain Vadeboncoeur, Montreal Heart Inst, Montréal, QC, Canada

12:15 PM

Prevalence and Factors Associated With Falls and Initiation of Fall Prevention Programs in Adults With Atrial Fibrillation: The ATRIA2-CVRN Study

**Jaejin An** , Kaiser Permanente Southern California, Pasadena, CA; Daniel E Singer, Massachusetts General Hosp, Boston, MA; Alan S Go, Kaiser Permanente Northern California, Oakland, CA; Margaret C Fang, Sachin J Shah, Univ of California San Francisco, San Francisco, CA; Sue Hee Sung, Kaiser Permanente Northern California, Oakland, CA; Teresa N Harrison, Kaiser Permanente Southern California, Pasadena, CA; Joan C Lo, Kaiser Permanente Northern California, Oakland, CA; Kristi Reynolds, Kaiser Permanente Southern California, Pasadena, CA

# Abstract Rapid Fire Oral

## IN.RFO21 - TAVR Dilemmas and Controversies

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 11:35 AM - 12:25 PM

11:35 AM

The Effect of Pre-Procedural Significant Mitral Regurgitation Upon Mortality After Transcatheter Aortic Valve Implantation

Stergios Soulaidopoulos, Hippokration Hosp, Athens, Greece; Konstantinos Toutouzas, Athens Medical Sch, Athens; Maria Drakopoulou, First Dept of Cardiolgy, Athens, Greece; George Oikonomou, **Konstantinos Stathogiannis** , Hippokration Hosp, Athens, Greece; George Latsios, NHS Greece, Athens; Maria Xanthopoulou, Pantelis Toskas, George Trantalis, Hippokration Hosp, Athens, Greece; Dimitrios Tousoulis, Ippokrateio Hosp, Athens, Greece

11:55 AM

Systolic Load, Ventricular Contractility, and Outcome in Transcatheter Aortic Valve Implantation: A Study Utilizing Combined Arterial Load and Systolic Elastance

**Matthew Gottbrecht** , Nouran Sorour, Bryan Dolan, UMass Medical Ctr, Worcester, MA; Eugene Chung, Ohio Heart and Vascular Cntr, Cincinnati, OH; Gerard P Aurigemma, Colleen Harrington, Univ of Massachusetts Medical Sch, Worcester, MA

12:05 PM

**Variation in Post-TAVR Antithrombotic Therapy and Outcomes in Patients With Preexisting Atrial Fibrillation: Insights From the STS/ACC TVT** ® **Registry**

**Aakriti Gupta** , Columbia Univ Medical Ce, New York, NY; Matthew W Sherwood, Inova Heart and Vascular Inst, McLean, VA; Zhuokai Li, Duke Univ, North Carolina, NC; Sreekanth Vemulapalli, Duke Univ Medical Ctr, Durham, NC; Ajay Kirtane, Columbia Univ Medical Ctr, New York, NY; Vinod H Thourani, Medstar Washington Hosp Ctr, Washington, DC; Eric D Peterson, Duke Clinical Res Inst, Chapel Hill, NC

12:15 PM

Frequency, Causes and Impact of Fever Following Transcatheter Aortic Valve Implantation

**David Jin** , St Vincent's Hosp Melbourne, Melbourne, Australia; Arul Baradi, St Vincent's Hosp, Melbourne, Australia; Philippa Trevella, Robert Whitbourn, St Vincent's Hosp Melbourne, Melbourne, Australia; Arthur Nasis, Monash Health, Melbourne, Australia; Andrew M Wilson, St Vincent's Hosp, Fitzroy, Australia; Jonathon Darby, Sonny Palmer, St Vincent's Hosp Melbourne, Melbourne, Australia

# Abstract Rapid Fire Oral

## WS.RFO27 - Women's Health and Sex Differences

#### Science and Technology Hall A, Booth 605, Level 2

### Sunday, November 17, 2019, 11:35 AM - 12:25 PM

11:35 AM

Moderator

Pamela Ouyang, Baltimore, MD

11:35 AM

Sex Differences on Mortality After Aortic Valve Replacement in Patients With Paradoxical Low Flow Severe Aortic Stenosis

**Ezequiel Guzzetti** , Anthony Poulin, IUCPQ, Quebec, QC, Canada; Mohamed-Salah Annabi, Québec Heart and Lung Inst, Québec-City, QC, Canada; Bin Zhang, IUCPQ, Quebec, QC, Canada; Dimitri Kalavrouziotis, Quebec Heart and Lung Inst, Quebec City, QC, Canada; Christian Couture, IUCPQ, Quebec, QC, Canada; Francois Dagenais, Laval Hosp, Quebec, QC, Canada; Philippe Pibarot, IUCPQ-UL, Quebec, QC, Canada; Marie Annick Clavel, IUCPQ, Quebec, QC, Canada

11:45 AM

Women Have a Higher 5-Year Risk of Stroke After Intervention for Carotid Stenosis Than Men

**Niveditta Ramkumar** , The Dartmouth Inst, Lebanon, NH; Bjoern D Suckow, Dartmouth-Hitchcock Medical Ctr, Lebanon, NH; Todd A MacKenzie, Geisel Sch of Med, Lebanon, NH; Art Sedrakyan, Weill Cornell Medical Coll, New York, NY; Philip P Goodney, Dartmouth-Hitchcock Medical Ctr, Lebanon, NH; Jeremiah Richardson Brown, Geisel Sch of Med, Lebanon, NH

11:55 AM

Hypertensive Disorders of Pregnancy Are Associated With Long-Term Risk of Diverse Cardiovascular Disease

**Michael C. Honigberg** , Massachusetts General Hosp, Boston, MA; Seyedeh Maryam Zekavat, Yale Sch of Med, Newton, MA; Krishna Aragam, Massachusetts General Hosp, Cambridge, MA; Derek Klarin, Massachusetts General Hosp, Boston, MA; Deepak L Bhatt, Brigham and Womens Hosp, Boston, MA; Nandita Scott, Massachusetts General Hosp, Boston, MA; Gina Peloso, Boston Univ Sch of Public, Boston, MA; Pradeep Natarajan, Massachusetts General Hosp, Boston, MA

12:05 PM

Ultra-High Sensitivity Cardiac Troponin I is Associated With Abnormal Coronary Reactivity: A Report From the Women's Ischemia Syndrome Evaluation - Coronary Vascular Dysfunction (WISE-CVD) Study

**Ahmed AlBadri** , Emory Univ Hosp, Atlanta, GA; Janet Wei, Cedars-Sinai Medical Ctr, Los Angeles, CA; Puja K Mehta, Emory Univ, Atlanta, GA; Yi Xiao, Emory Univ Hosp, Atlanta, GA; Yi-An Ko, Emory Univ, Atlanta, GA; R David D Anderson, John William Petersen, Univ of Florida, Gainesville, FL; Babak Azarbal, Cedars Sinai Heart Inst, Beverly Hills, CA; Bruce Samuels, Cedars Sinai Heart Inst, beverly hills, CA; Timothy D Henry, Cedars Sinai Medical Ctr, Cincinnati, OH; Galen Cook-Weins, Cedars Sinai Medical Ctr, Los Angeles, CA; Eileen M Handberg, Univ Florida, Gainesville, FL; Jennifer E Van Eyk, Cedar Sinai Medical Ctr, Los Angeles, CA; Carl Pepine, Univ of Florida, Gainesville, FL; Noel N Merz, Cedars-Sinai Medical Ctr, Los Angeles, CA

12:15 PM

Sex Differences in the Inflammatory Response to Stress and Risk of Adverse Cardiovascular Outcomes

**Samaah Sullivan** , An Young, Muhammad Hammadah, Bruno B. Lima, Yi-An Ko, Brad D. Pearce, Amit J. Shah, Jeong Hwan Kim, Kasra Moazzami, Nancy Murrah, Emily G. Driggers, Belal Kaseer, Oleksiy Levantsevych, Ammer Haffar, Laura Ward, Allison Hankus, Tene T. Lewis, Puja K. Mehta, J. Douglas Bremner, Emory Univ, Atlanta, GA; Paolo Raggi, Mazankowski Alberta Heart Inst., Univ of Alberta, Edmonton, AB, Canada; Arshed A Quyyumi, Viola Vaccarino, Emory Univ, Atlanta, GA

# Moderated Digital Posters

## LF.MDP44 - Cardiorespiratory Fitness: Digging Deep Into Measurement and Meaning

#### Moderated Posters 7, Science and Technology Hall

### Sunday, November 17, 2019, 11:35 AM - 12:25 PM

11:35 AM

Moderator

Jennifer E Ho, Newton, MA

11:35 AM

Cardiorespiratory Fitness Moderates Heart Failure Incidence in High-risk African-Americans

**Konstantinos Imprialos** , VAMC and Georgetown Univ, Washington, DC; Peter F Kokkinos, Verterans Affairs Medical Ctr, Annapolis, MD; Andreas Pittaras, VAMC Washington DC, Washington, DC; Konstantinos Stavropoulos, VAMC and Georgetown Univ, Washington, DC; Charles Faselis, VAMC and George Washington Univ, Washington, DC; Pamela Karasik, VAMC, Washington, DC; Michael Doumas, VAMC and Georgetown Univ, Washington, DC; Hans Moore, VAMC, Washington, DC; Vasilios Papademetriou, VAMC and Georgetown Univ, Washington, DC

11:40 AM

Q & A

11:45 AM

The Association Between Cardiorespiratory Fitness Normalized to Fat-Free Mass and Mortality Risk

**Mary T Imboden** , George Fox Univ, Health Enhancement Res Organization, Newberg, OR; Matthew P Harber, Mitchell H Whaley, Jim E Peterman, Bradley S Fleenor, Leonard A Kaminsky, Ball State Univ, Muncie, IN

11:50 AM

Q & A

11:55 AM

Association of Directly Measured and Non-Exercise-Based Estimated Cardiorespiratory Fitness Among Physically Inactive Adults: A Secondary Analysis of the Activity Counseling Trial

**Kershaw V Patel** , Ambarish Pandey, Karrie Curry, Colby Ayers, Jarett D Berry, UT Southwestern Medical Ctr, Dallas, TX

12:00 PM

Q & A

12:05 PM

Cardiopulmonary Exercise Testing as a Prognostic Indicator in Patients With Preserved Exercise Capacity

**Takamasa Sato** , Akiomi Yoshihisa, Yuki Kanno, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

12:10 PM

Q & A

12:15 PM

Finding An Optimal Measure Of Fitness To Predict Mortality: Anaerobic Threshold Versus Oxygen Consumption

Sergey Kachur, Ochsner Clinic Fndn, New Orleans, LA; Alban DeSchutter, Carson Tahoe Medical Group Cardiology, Carson City, NV; Carl Joseph Lavie Jr., Ochsner Health System, New Orleans, LA; Andrew Elagizi, **Rikin Kadakia** , Ochsner Clinic Fndn, New Orleans, LA; Richard V Milani, Ochsner Health System, New Orleans, LA

12:20 PM

Q & A

# Moderated Digital Posters

## AT.MDP41 - Endothelium, Vascular Tone and Nitric Oxide

#### Moderated Posters 6, Science and Technology Hall

### Sunday, November 17, 2019, 11:35 AM - 12:25 PM

11:35 AM

Moderator

Ming-hui Zou, Atlanta, GA

11:35 AM

Discovery of Neurovascular Reactivity During a Standard 5-minute Arm-cuff Reactive Hyperemia - Data From 7105 Patient Registry

Ruoyu Zhuang, Univ of Houston, HOUSTON, TX; Ahmed Gul, Univ of Houston, Houston, TX; Albert Yen, Endothelix, Houston, TX; Hirofumi Tanaka, Univ of Texas Austin, Austin, TX; Ralph Metcalfe, Univ of Houston, HOUSTON, TX; Stanley Kleis, Univ of Houston, Houston, TX; **Morteza Naghavi** , SHAPE, Palo Alto, CA

11:40 AM

Q & A

11:45 AM

Association of Reactive Hyperemia Index and Optical Coherence Tomography-assessed Coronary Plaque Morphology in Patients With Coronary Artery Disease

**Nobuaki Suzuki** , Takahiro Kimura, Seiji Nishide, Takashi Aoyagi, Kenta Kanamori, Yoshitaka Shiratori, Noriyuki Hayami, Teikyo Mizonokuchi Hosp, Kawasaki, Japan; Ken Kozuma, Teiyko Univ, Tokyo, Japan

11:50 AM

Q & A

11:55 AM

The Effects of Tobacco Smoking and Electronic Cigarette Use on the Level of Albuminuria and Vascular Augmentation Index in Young Healthy Population

Anna Bragina, Natalia Druzhinina, First Moscow State Medical Univ, I.M. Sechenov, Moscow, Russia, Moscow, Russian Federation; **Leila Mohammadi** , UCSF, San Francisco, CA; Evgenii Khvalin, Artem Dubchak, Luba Vasilyeva, First Moscow State Medical Univ, I.M. Sechenov, Moscow, Russia, Moscow, Russian Federation; Valery Podzolkov, First, Moscow, Russian Federation

12:00 PM

Q & A

12:05 PM

Hemodynamic Effect of Sildenafil in Fetal Lambs

Kasper Pryds, Aarhus Univ Hosp Skejby, Aarhus N; Michael Schmidt, Vibeke Hjortdal, Rigshospitalet, Copenhagen, Denmark; **Rajiv Chaturvedi** , The Hosp for Sick Children, Toronto, ON, Canada

12:10 PM

Q & A

12:15 PM

Overnutrition Causes Insulin-Dependent De-Novo Lipogenic Pathways to Become Overactive in Liver Yet Underactive in Endothelium: a Molecular Explanation

**Xiangdong Wu** , Kevin Jon Williams, Lewis Katz Sch of Med at Temple Univ, Philadelphia, PA

12:20 PM

Q & A

# Moderated Digital Posters

## MP.MDP38 - Experimental Ischemia

#### Moderated Posters 5, Science and Technology Hall

### Sunday, November 17, 2019, 11:35 AM - 12:25 PM

11:35 AM

Sestrin2 Plays a Role in an Age-related Maladaptive Response to Cardiac Ischemia/reperfusion Injury

**Di Ren** , Nanhu Quan, Jingwen Zhang, Xuan Li, Ji Li, Univ of South Florida, Tampa, FL

11:40 AM

Q & A

11:45 AM

Sestrin2 Acts as an Adaptive Stress-Inducing Protein That Alleviates Age-related Cardiac Dysfunction

**Nanhu Quan** , Jilin Univ, Changchun, China; Ji Li, Univ of South Florida, Tampa, FL

11:50 AM

Q & A

11:55 AM

Apolipoprotein A1 Attenuates Myocardial Ischemia-Reperfusion Injury by Blocking the Release of Cell-Free DNA and HMGB1 From Ischemically-Injured Myocardium

**Aimee Zhang** , Lina Lai, Eric J Charles, Univ of Virginia, Charlottesville, VA; Irving L Kron, Univ of Arizona, Tuscon, AZ; Zequan Yang, Univ of Virginia, Charlottesville, VA

12:00 PM

Q & A

12:05 PM

Effect of Hyperoxia on Coronary Artery Circulatory Mechanisms Determining Blood Flow Variations

**Tariq Ali Ahmad** , Penn State Univ Medical Cente, Hershey, PA; Urs Leuenberger, Pradeep Yadav, Div of Cardiology H047, Hershey, PA; Ian Gilchrist, Charles Chambers, Abdul Basit, Hummelstown, PA; Matthew Muller, Penn State Univ Coll of Med, Wickliffe, OH; Hajduczok Alexander, Penn State Univ Medical Cente, Hershey, PA; Lawrence Sinoway, Pennsylvania State Univ, Hershey, PA

12:10 PM

Q & A

12:15 PM

Cardioprotective Effects and Myocardial Expression of MiRNA 223, RIP-1 and MLKL After Necroptosis Inhibition in a Rat Model of Heterotopic Allogeneic Heart Transplantation

**Yuri Dmitriev** , Almazov Natl Medical Res Ctr, Saint-Petersburg, Russian Federation; Lubov Vasina, Saint Petersburg Pavlov State Medical Univ, Saint-Petersburg, Russian Federation; Michael Galagudza, Almazov Natl Medical Res Ctr, St-Petersburg, Russian Federation

12:20 PM

Q & A

# Moderated Digital Posters

## CA.MDP35 - Heart Failure

#### Moderated Posters 4, Science and Technology Hall

### Sunday, November 17, 2019, 11:35 AM - 12:25 PM

11:35 AM

Low-intensity Pulsed Ultrasound Ameliorates Cardiac Diastolic Dysfunction in Mice -a Potential Novel Therapeutic Strategy for Heart Failure With Preserved Ejection Fraction-

**Yuto Monma** , Tohoku Univ Graduate Sch of Med, Sendai, Japan; Tomohiko Shindo, Tohoku Univ, Sendai City, Japan; Ryo Kurosawa, Tohoku Univ, Sendai, Japan; Sadamitsu Ichijo, Tohoku Univ Graduate Sch of Med, Sendai Miyagi, Japan; Takashi Nakata, Tohoku Univ Graduate Sch of Med, Sendai-Shi Miyagi, Japan; Ayana Matsumoto, Haruka Sato, Masahito Miura, Tohoku Univ, Sendai, Japan; Hiroaki Shimokawa, Tohoku Univ, Sendai City, Japan

11:40 AM

Q & A

11:45 AM

Right Ventricular Longitudinal Strain Post-Acute Pulmonary Embolism is an Independent Predictor of Mortality

**Mohammad Hashim Mustehsan** , Aliaskar Hasani, Albert Einstein Coll of Med/Montefiore Medical Ctr, Bronx, NY; Renato Quispe, Albert Einstein Coll of Med/Jacobi Medical Ctr, Bronx, NY; Mihai Andreca, Albert Einstein Coll of Med/Montefiore Medical Ctr, Bronx, NY; Jaspreet Bhatti, Northeast Ohio Medical Univ, Rootstown, OH; Cynthia C Taub, Albert Einstein Coll of Med/Montefiore Medical Ctr, Bronx, NY

11:50 AM

Q & A

11:55 AM

Effects of Prostaglandin E1 on Left Ventricular Systolic and Diastolic Performance in Conscious Dogs With Pacing-Induced Heart Failure - Assessment by Pressure-Volume Analysis

**Tiankai Li** , Heng-Jie Cheng, Zhi Zhang, Satoshi Masutani, Xiaowei Zhang, David Herrington, Che Ping Cheng, Wake Forest Sch of Med, Winston-Salem, NC

12:00 PM

Q & A

12:05 PM

Mathematical Modeling of Right Ventricular Energetics and Efficiency to Enable Discrimination Between NYHA II and III/IV Pulmonary Arterial Hypertension Patients

**Jacqueline V Scott** , Tanuf Tembulkar, Carnegie Mellon Univ, Pittsburgh, PA; Bradley Faliks, Northwell Health, Plainview, NY; Kelly Koch, Barnes-Jewish Hosp, St Louis, MN; Meng-Lin Lee, Univ of Michigan, Ann Arbor, MI; Keith Cook, Carnegie Mellon Univ, Pittsburgh, PA

12:10 PM

Q & A

12:15 PM

Activation of Invariant Natural Killer T Cells Ameliorates Doxorubicin-Induced Cardiomyopathy

**Masashi Sada** , Kyushu Univ, Fukuoka, Japan; Shouji Matsushima, Kyushu Univ Hosp, Fukuoka, Japan; Soichiro Ikeda, Kosuke Okabe, Akihito Ishikita, Tomonori Tadokoro, Nobuyuki Enzan, Taishi Yamamoto, Hiroko Deguchi, Masataka Ikeda, Tomomi Ide, Hiroyuki Tsutsui, Kyushu Univ, Fukuoka, Japan

12:20 PM

Q & A

# Moderated Digital Posters

## IN.MDP32 - Innovative Interventional Technologies: Welcome to the 21st Century.

#### Moderated Posters 3, Science and Technology Hall

### Sunday, November 17, 2019, 11:35 AM - 12:25 PM

11:35 AM

Moderator

Sunil V Rao, Durham, NC

11:35 AM

**Artificial Intelligence Trumps TAVI** 2 **-SCORE in Predicting 1yr Survival Post Post Transcatheter Aortic Valve Replacement**

**Pradyumna Agasthi** , Farouk Mookadam, Mayo Clinic, Scottsdale, AZ; Nithin Venepally, Mayo Clinic, Phoenix, AZ; Marlene Girardo, Matthew Buras, Banveet K Khetarpal, Mayo Clinic, Scottsdale, AZ; Mackram Eleid, Kevin Greason, Mayo Clinic, Rochester, MN; Nirat Beohar, Columbia Univ Div, Miami Beach, FL; John Sweeney, Mayo Clinic, Scottsdale, AZ; F D Fortuin II, Mayo Clinic, Phoenix, AZ; David R Holmes, Mayo Clinic, Rochester, MN; Reza Arsanjani, Mayo Clinic, Scottsdale, AZ

11:40 AM

Q & A

11:45 AM

The Impact of Baseline Aortic Regurgitation on the Degree of Left Ventricular Remodeling After Transcatheter Aortic Valve Implantation

**Abdalla Hassan** , Cecilia Wong, UMass Medical Sch, Worcester, MA; Ashraf Abugroun, AIMMC, Chicago, IL; Colleen Harrington, Nikolaos Kakouros, Gerard Aurigemma, UMass Medical Sch, Worcester, MA

11:50 AM

Q & A

11:55 AM

Metaanalysis Comparing Safety and Outcomes After Transcatheter Aortic Valve Replacement in Bicuspid Aortic Stenosis

**Srilekha Sridhara** , Prajakta U Gavhane, Banner Univ Medical Ctr-Phoenix, Phoenix, AZ; Bhavi Pandya, Staten Island Univ Hosp, Northwell Health, Staten Island, NY; Arnav Kumar, Emory Univ Sch of Med, Atlanta, GA; Nidhi Kanwar, Banner Univ Medical Ctr-Phoenix, Phoenix, AZ; Janelle Rodriguez, Univ of Arizona, Phoenix, AZ; Meghana Prakash, Banner Univ Medical Ctr-Phoenix, Phoenix, AZ; Varun Kohli, East Tennessee State Univ, Johnson City, TN; Gary Tse, The Chinese Univ of Hong Kong, Shatin, China; Tong Liu, Tianjin Inst of Cardiology, Tianjin, China; Hemang B Panchal, East Tennessee State Univ, Johnson City, TN

12:00 PM

Q & A

12:05 PM

CRyo Ablation of Septal Hypertrophy (CRASH) in HOCM

**Aharon Medina** , Michael Ilan, Adi Butnaru, Arik Wolak, Rafael Wolff, Shaare Zedek Medical Ctr, Jerusalem, Israel; Marc Klutstein, Shaare Zedek Medical center, Jerusalem, Israel; Moshe Rav Acha, David Meerkin, Yaron Almagor, Dan Tzivoni, Michael Glikson, Shaare Zedek Medical Ctr, Jerusalem, Israel

12:10 PM

Q & A

12:15 PM

Transcatheter Leak Occlusion With Detachable Coils Following Left Atrial Appendage Closure

**Domenico Giovanni Della Rocca** , St.David's Medical Ctr, Austin, TX; Rodney Paul Horton, TCAI, Austin, TX; Luigi Di Biase Sr., Albert Einstein Coll of Med, New York, NY; Sanghamitra Mohanty, St.Davids Medical Ctr, Austin, TX; Amin Al-Ahmad, Mohamed Bassiouny, St.David's Medical Ctr, Austin, TX; Chintan G Trivedi, Texas Cardiac Arrhythmia Inst, Austin, TX; Bryan MacDonald, TCAI, Austin, TX; Alessio Gasperetti, Monzino Hosp, Milan, Italy; Veronica Natale, Johns Hopkins Univ, Baltimore, MD; Carola Gianni, Texas Cardiac Arrhythmia Inst, Austin, TX; J David Burkhardt, G Joseph Gallinghouse, St.David's Medical Ctr, Austin, TX; Javier Sanchez, TCAI, Austin, Italy; Andrea Natale, St.David's Medical Ctr, Austin, TX

12:20 PM

Q & A

# Moderated Digital Posters

## CH.MDP26 - New Perspectives on Understanding Long-Term Outcomes in Tetralogy of Fallot

#### Moderated Posters 1, Science and Technology Hall

### Sunday, November 17, 2019, 11:35 AM - 12:25 PM

11:35 AM

Changes in Circulating Whole Genome Micro RNA Expression Implicate Cell Cycle Dysregulation as a Key Mediator Of Right Ventricular Failure in Adults With Tetralogy of Fallot

**Chad S Weldy** , Saad A Syed, Dong-Qing Hu, Xuhuai Ji, Anne Taylor, Brittany Navarre, Stanford Univ, Stanford, CA; Sushma Reddy, Stanford Univ, Palo Alto, CA

11:40 AM

Q & A

11:45 AM

Paradoxical Decrease in Biventricular Strain After Pulmonary Valve Replacement in Patients With Repaired Tetralogy Fallot: Insights From a Longitudinal Cardiovascular Magnetic Resonance Study

**Kazuhiro Shiraga** , Quynh Tran, Nazire Ozcelik, Matthew A Harris, Kevin K Whitehead, David M Biko, Sara Partington, Mark Alan Fogel, The Children's Hosp of Philadelphia, Philadelphia, PA

11:50 AM

Q & A

11:55 AM

Natural History of Aortic Growth After Tetralogy of Fallot Repair

**Max T Geisinger** , Hosp of the Univ of Pennsylvania, Philadelphia, PA; Jungwon W Min, The Children's Hosp of Philadelphia, Philadelphia, PA; Tanmay Bhamare, Hosp of the Univ of Pennsylvania, Philadelphia, PA; Katherine Awh, Sharon Edman, Melissa Wasserman, Elizabeth Goldmuntz, The Children's Hosp of Philadelphia, Philadelphia, PA; Yuli Y Kim, Hosp of the Univ of Pennsylvania, Philadelphia, PA

12:00 PM

Q & A

12:05 PM

Transfer Learning for Automated Aortic Segmentation and Assessment of Aortic Mechanics in Tetralogy of Fallot: Multi-Ethnic Study of Atherosclerosis and the German Competence Network for Congenital Heart Defects

**Vivek P Jani** , Johns Hopkins Univ - MSTP, Baltimore, MD; Eric Xie, Julie Shade, Johns Hopkins Univ, Baltimore, MD; Lasya Gaur, Johns Hopkins Hosp, Baltimore, MD; Andreas Schuster, Univ Med Goettingen, Goettingen, Germany; Samir Sarikouch, Hannover Medical Sch, Hannover; Gerhard-Paul Diller, , Royal Brompton Hosp, London, UK, London, United Kingdom; Cedric Manlhiot, The Hosp for Sick Children, Toronto, ON, Canada; Joao A Lima, Bharath Ambale-Venkatesh, Johns Hopkins Univ, Baltimore, MD; Shelby Kutty, Johns Hopkins Hosp, Baltimore, MD

12:10 PM

Q & A

12:15 PM

Echocardiographic Predictors of Severe Right Ventricular Diastolic Dysfunction in Tetralogy of Fallot: Relations to Patient Outcomes

**Alexander C Egbe** , Mayo Clinic, Rochester, MN

12:20 PM

Q & A

# Moderated Digital Posters

## QU.MDP47 - Reducing Hospital Readmissions

#### Moderated Posters 8, Science and Technology Hall 

### Sunday, November 17, 2019, 11:35 AM - 12:25 PM

11:35 AM

Moderator

Shannon M Dunlay, Rochester, MN

11:40 AM

Q & A

11:45 AM

Hospital Readmissions Reduction Program: Decrease in Heart Failure Readmissions and Mortality

**Malik Bilal Ahmed** , Brown Univ, Providence, RI; Anshul Parulkar, Wasiq Sheikh, Rhode Island Hosp, Providence, RI; Sanchita Singal Parulkar, Esseim Sharma, Brian Daniel McCauley, Brown Univ, Providence, RI; Lauren Rousseau, Cardiovascular Inst, Providence, RI; Antony F Chu, Brown Univ, Providence, RI

11:50 AM

Q & A

11:55 AM

Post-Discharge Acute Care and Outcomes in the Era of Readmission Reduction

**Rohan Khera** , Univ of Texas Southwestern Medical Ctr, Dallas, TX; Yongfei Wang, Yale Univ Sch of Med, Cheshire, CT; Susannah Bernheim, YALE/YNHH CORE, New Haven, CT; Zhenqiu Lin, Yale-New Haven Hosp, New Haven, CT; Harlan M Krumholz, Yale Univ Sch of Med, New Haven, CT

12:00 PM

Q & A

12:05 PM

Comparison of 1 Year Pre- and Post-Transcatheter Aortic Valve Replacement Hospitalization Rates: A Population-based Cohort Study

**Andrew Czarnecki** , Sunnybrook Health Sciences Ctr, Toronto, ON, Canada; Feng Qiu, Kayley Henning, Inst of Clinical Evaluative Sciences, Toronto, ON, Canada; Jiming Fang, ICES, Toronto, ON, Canada; Michelle Jennett, Sunnybbrook Health Sciences Ctr, Toronto, ON, Canada; Peter Austin, Inst for Clinical Evaluative S, Toronto, ON, Canada; Dennis T Ko, ICES, Toronto, ON, Canada; Sam Radhakrishnan, Harindra C Wijeysundera, Sunnybrook Health Sciences Ctr, Toronto, ON, Canada

12:10 PM

Q & A

12:15 PM

Home Healthcare Post-discharge Outcomes After Heart Failure Hospitalization: An American Heart Association Get With the Guidelines-heart Failure Study

**Madeline R. Sterling** , Monika M Safford, Lisa M Kern, Weill Cornell Medical Coll, New York, NY; Christine D Jones, Univ of Colorado Denver - Anschutz Medical Campus, Aurora, CO; Penny H Feldman, Visiting Nurse Service of New York, New York, NY; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; Shubin Sheng, Roland Matsouaka, Adam David Devore Sr., Barbara Lytle, Duke Clinical Res Inst, Durham, NC; Larry A Allen, Univ of Colorado Denver - Anschutz Medical Campus, Aurora, CO; Anita M Deswal, Michael E. DeBakey VAMC, Houston, TX; Clyde W Yancy, Northwestern Univ, Chicago, IL; Nancy M Albert, Cleveland Clinic, Chesterland, OH

12:20 PM

Q & A

# Moderated Digital Posters

## HF.MDP29 - Understanding Variability of Outcomes in Your Patients with Heart Failure and Cardiomyopathy

#### Moderated Posters 2, Science and Technology Hall

### Sunday, November 17, 2019, 11:35 AM - 12:25 PM

11:35 AM

Impact of Depression in Heart Failure With Preserved Ejection Fraction

**Diana A Chirinos** , Northwestern Univ Feinberg Sch of Med, Chicago, IL; Mary Jo Obeid, Univ of Pennsylvania, Philadelphia, PA; Anupam Kumar, Vanderbilt Univ, Nashville, TN; Jonathan Lee, Payman Zamani, Univ of Pennsylvania, Philadelphia, PA; Stuart Prenner, Univ of Pennsylvania, Philadephia, PA; Julio A Chirinos, Univ of Pennsylvania, Philadelphia, PA

11:40 AM

Q & A

11:45 AM

Early and Late Readmission Rates for Heart Failure Hospitalizations in Patients With Preserved and Reduced Ejection Fraction: Insights From the Nationwide Readmission Database 2010-2016

**Ahmed Elkaryoni** , Univ of Missouri-Kansas City, Kansas City, MO; Jonathan Enriquez, Saint-Luke's Mid America Heart Inst/ Univ of Missouri- Kansas City, Kansas City, MO

11:50 AM

Q & A

11:55 AM

Right Ventricular Function in Takotsubo Cardiomyopathy

**Arash Nayeri** , Pooja Desai, UCLA, Los Angeles, CA; Thomas Reed, Vanderbilt Univ Medical Ctr, Nashville, TN; Alexander Yuen, Cher Huang, Kathryn Cardoza, Univ of California, Los Angeles (UCLA), Los Angeles, CA; Kamran Shamsa, UCLA, Los Angeles, CA; Quinn Wells, Vanderbilt Univ, Nashville, TN; Eric H Yang, UCLA Medical Ctr, Culver City, CA; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA

12:00 PM

Q & A

12:05 PM

Prognosis of Breast Cancer and Heart Failure in Postmenopausal Women

**Phillip H Lam** , Ana Barac, MedStar Heart and Vascular Inst, Washington, DC; Anju Nohria, Brigham and Women's Hosp, Boston, MA; Kerryn Reding, Univ of Washington, Seattle, WA; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; Kathy Pan, Los Angeles Biomedical Res Inst, Torrance, CA; Helen Sheriff, DC VAMC, Washington, DC; Charity Morgan, Univ of Alabama-Birmingham, Birmingham, AL; Samer S Najjar, Medstar Washington Hosp Ctr, Washington, DC; Rowan Chlebowski, UCLA Torrance, Torrance, CA; Liviu Klein, Univ of California, San Francisco, CA; Charles B Eaton, Brown Univ, Pawtucket, RI; Barbara V Howard, Medstar Health and Georgetown U, Bonita Spgs, FL; Ali Ahmed, VA Medical Ctr, Washington, DC; Selma Mohammed, Mayo Clinic Rochester Coll Med, Washington, DC

12:10 PM

Q & A

12:15 PM

Local Brain Atrophy of Parahippocampal Gyrus is Prominent in Malnourished Heart Failure Patients Without Dementia

**Tomomi Meguro** , Ichikawa Hosp, IUHW, Ichikawa-shi Chibaken, Japan; Yuko Meguro, Asakusa Clinic, Tokyo, Japan; Toshio Nagai, Ichikawa Hosp, IUHW, Ichikawa, Japan

12:20 PM

Q & A

# Expert Theater

## ET.12 - Amgen, Inc.

#### Game Central, Booth # 6

### Sunday, November 17, 2019, 12:00 PM - 12:45 PM

This is not a CME/CE certified session

# Expert Theater

## ET.13 - Amgen, Inc.

#### Learning Studio 1, Booth # 5

### Sunday, November 17, 2019, 12:00 PM - 12:45 PM

This is not a CME/CE certified session

# Expert Theater

## ET.14 - Janssen Pharmaceuticals, Inc

#### Heart Theater, Booth # 17

### Sunday, November 17, 2019, 12:00 PM - 12:45 PM

This is not a CME/CE certified session

# Expert Theater

## ET.15 - Novartis Pharmaceuticals Corp.

#### Learning Studio 2, Booth # 7

### Sunday, November 17, 2019, 12:00 PM - 12:45 PM

This is not a CME/CE certified session

# Abstract Poster Session

## HF.APS.22 - Adverse Risk Predictors in Heart Failure

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2287

Incidence, Source, Determinants, and Prognostic Impact of Major Bleeding in Outpatients With Chronic Heart Failure: Insights From the CARDIONOR Registry

**Gilles Lemesle** , Sandro Ninni, Pascal De Groote, Nicolas Lamblin, Christophe Bauters, Inst Coeur Poumon, CHU de Lille, Lille Cedex, France

12:30 PM

Board # 2288

Outcome of Atrial Fibrillation in Patient With Heart Failure With Reduced Ejection Fraction Versus Heart Failure With Preserved Ejection Fraction, a 5-year Nationwide Analysis

**Claire Huang Lucas** , Mount Sinai St Luke's-West Hosp, NYC, NY; Bing Yue, Mount Sinai St. Luke's-West Hosp, New York, NY; Robert Abed, Mount Sinai St Luke's-West hospital, New York, NY; Nikhil Bachoo, Mount Sinai St. Luke's-West, New York, NY; Lingling Wu, Mount Sinai St Luke's and West, New York, NY; Jan Menezes Lopes, Mount Sinai St Luke's-West Hosp, NYC, NY; Xin Wei, Eyal Herzog, Mount Sinai St Luke's-West Hosp, New York, NY

12:30 PM

Board # 2289

Functional Iron Deficiency is Independently Associated With Increased Risk of Morbidity and Mortality in Older Adults With Heart Failure and Incident Anemia

**Andrew P Ambrosy** , Kaiser Permanente, San Francisco, CA; Grace Tabada, Kaiser Permanente, Oakland, CA; Jerry Gurwitz, Univ of Massachusetts, Worcester, MA; Andrew Artz, Univ of Chicago, Chicago, IL; Stanley Schrier, Stanford Univ, Palo Alto, CA; Sunil V Rao, Duke Univ Medical Ctr, Durham, NC; Kristi Reynolds, Kaiser Permanente, Pasadena, CA; David H Smith, Kaiser Permanente Northwest, Portland, OR; Pamela Nicole Peterson, Univ of Colorado, Aurora, CO; Sue Hee Sung, Kaiser Permanente, Oakland, CA; Harvey Cohen, Duke Univ, Durham, NC; Alan S Go, Kaiser Permanente, Oakland, CA; RBC HEART Investigators/PACTTE Consortium

12:30 PM

Board # 2290

The Influence of Heart Failure on Clinical and Economic Outcomes for Older Patients Presenting With Acute Myocardial Infarction

**Abdulla A Damluji** , Inova Heart and Vascular Inst, Falls Church, VA; Wayne B. Batchelor, St Michael's Hosp Cardiology Dept, Tallahassee, FL; Behnam Tehrani, INOVA Heart and Vascular Inst, Falls Church, VA; Paul A Gurbel, Inova Heart and Vascular, Lutherville, MD; Kelly Epps, Inova Heart and Vascular Inst, Washington, DC; Matthew W Sherwood, Inova Heart and Vascular Inst, McLean, VA; Narian Rajan, Inova Heart and Vascular Inst, Falls Church, VA; Rahsaan C Smith, Inova Heart, Pittsburgh, PA; Shashank Sinha, Inova Heart and Vascular Inst, Falls Church, VA; Shashank Desai, Inova Heart, Falls Church; Lauren Cooper, Inova Heart and Vascular Inst, Falls Church, VA; Mitchell Psotka, UCSF, San Francisco, CA; Christopher DeFilippi, Inova, Falls Church, VA; Christopher O'Connor, Inova Heart, Falls Church, VA

12:30 PM

Board # 2291

Recurrent Admissions for Acute Decompensated Heart Failure Among Patients With and Without Peripheral Artery Disease: The Atherosclerosis Risk in Communities Study

**Zainali Chunawala** , Seth GS Medical Coll and KEM Hosp, Mumbai, India; Patricia Chang, Univ of North Carolina, Chapel Hill, NC; Andrew Paul DeFilippis, Univ of Louisville, Louisville, KY; Michael E Hall, Univ of Mississippi Medical Ctr, Jackson, MS; Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD; Melissa Caughey, Univ of North Carolina, Chapel Hill, NC

12:30 PM

Board # 2292

Mild to Moderate Aortic Regurgitation is Associated With Increased All-Cause Mortality in Patients Hospitalized for Acute Heart Failure

**Tamila Abdurashidova** , Lausanne Univ Hosp, Lausanne, Switzerland; Martin Müller, Bern Univ Hosp, Bern, Switzerland; Georgios Tzimas, Nicolas Barras, Patrick Oliver Yerly, Julien Regamey, Olivier Hugli, Matthias Kirsch, Pierre Monney, Roger Hullin, Lausanne Univ Hosp, Lausanne, Switzerland

12:30 PM

Board # 2293

Treatment of Sleep Disordered Breathing With Positive Airway Pressure Therapy Reduces the Number of Hospitalizations in a Large Cohort of Patients With Heart Failure

**Salma I Patel** , Monica Vasquez, Stefano Guerra, Daniel Combs, Sairam Parthasarathy, Univ of Arizona Coll of Med, Tucson, AZ

12:30 PM

Board # 2294

Long-Term Prevalence and Predictors of Fatal Arrhythmic Events After Discharge in Patients With Acute Decompensated Heart Failure With Reduced Ejection Fraction

**Reo Hata** , Kurashiki Central Hosp, Kurashiki, Japan; Hidenori Yaku, Kyoto Univ Graduate Sch of Med, Kyoto, Kyoto, Japan; Takeshi Morimoto, Hyogo Coll of Med, Nishinomiya, Japan; Moritake Iguchi, Kyoto Medical Ctr, Kyoto, Japan; Yasutaka Inuzuka, Kyoto Univ, Kyoto, Japan; Yodo Tamaki, Tenri Hosp, Tenri City, Japan; Neiko Ozasa, Kyoto Univ Hosp, Kyoto, Japan; Erika Yamamoto, Kyoto Univ Graduate Sch of Med, Kyoto, Kyoto, Japan; Yuichi Kawase, Kazushige Kadota, Kurashiki Central Hosp, Kurashiki, Japan; Takao Kato, Kyoto Univ, Kyoto, Japan; Takeshi Kimura, Kyoto Univeristy, Kyoto, Japan

12:30 PM

Board # 2295

Using a Machine Learning Platform to Identify Causal Pathways and Predictors of Length of Stay Among Patients Hospitalized for Acute Heart Failure Hospitalization in an Electronic Health Records Database

**Ella Nkhoma** , Bristol-Myers Squibb, Pennington, NJ; Maria Borentain, Bristol-Myers Squibb, Princeton, NJ; Paul Kessler, Bristol-Myers Squibb, Lawrenceville Township, NJ; Jenny Jiang, Bristol-Myers Squibb, Lawrenceville, NJ; Luke Lueller, GNS Healthcare, Cambridge, MA; Aylin Tugcu, Mary M DeSouza, Bristol-Myers Squibb, Princeton, NJ

12:30 PM

Board # 2296

A New Systemic Inflammation-nutrition Index Provides the Additional Long-term Prognostic Information to the Get With the Guidelines-heart Failure Risk Score in Acute Decompensated Heart Failure

**Takahisa Yamada** , Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masahiro Seo, Osaka General Medical Ctr, Osaka City, Japan; Makoto Abe, Jun Nakamura, Kyoko Yamamoto, Kiyomi Kayama, Osaka General Medical Ctr, Osaka, Japan; Kazuya Tanabe, Osaka General Medical Ctr, Osaka, NY; Yuto Tamura, Takeshi Fujita, Masatake Fukunami, Osaka General Medical Ctr, Osaka, Japan

12:30 PM

Poster Professor

Lynne Warner Stevenson, Nashville, TN

# Abstract Poster Session

## VA.APS.04 - All Around the World: International Perspectives on Vascular Disease Research

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4346

Arterial Age and Early Vascular Aging Predict Future Thoracic Aortic Aneurysm Expansion

**Nicolas D Santi** , The Ottawa Hosp, Ottawa, ON, Canada; Munir Boodhwani, Univ Ottowa Heart Inst, Ottawa, ON, Canada; Luc M Beauchesne Jr., Ottawa Heart Inst, Ottawa, ON, Canada; Kwan L Chan, Univ Ottowa Heart Inst, Ottawa, ON, Canada; Carole Dennie, Univ of Ottawa Heart Intsitut, Ottawa, ON, Canada; Sudhir Nagpal, The Ottawa Hosp, Ottawa, ON, Canada; George Wells, Thais Coutinho, Univ of Ottawa Heart Inst, Ottawa, ON, Canada

12:30 PM

Board # 4348

Management Of Submassive Pulmonary Embolism By Catheter Directed Thrombolysis: A Retrospective Analysis

Abhinav C Krishnan, **Dhruvil A Patel** , Alec Bonifer, Brian Reed, Mahir Elder, Brian O'Neil, Vijaya Arun Kumar, Wayne State Univ, Detroit, MI

12:30 PM

Board # 4349

Prevention of Aneurysm Progression by a Peptide Vaccine Against Angiotensin II in a Rat Model

**Tomohiro Kurashiki** , Takashi Miyake, Hironori Nakagami, Graduate Sch of Med, Osaka Univ, Suita, Osaka, Japan; Motonobu Nishimura, Faculty of Med, Tottori Univ, Yonago, Tottori, Japan; Ryuichi Morishita, Osaka Univ, Suita City, Japan

12:30 PM

Board # 4350

LDL-Triglyceride Content, LDL-Cholesterol to LDL-Triglyceride Ratio,and Associations With Incident Cardiovascular Disease: Prospective Data From the Women's Health Study

**Edward K Duran** , Brigham and Women's Hosp, Boston, MA; Aaron W Aday, Vanderbilt Medical Ctr, Nashville, TN; Nancy R Cook, Brigham and Womens Hosp, Boston, MA; Julie E Buring, Harvard Medical Sch, Boston, MA; Paul M Ridker, Brigham Womens Hosp, Boston, MA; Aruna D Pradhan, Brigham and Womens Hosp, Boston, MA

12:30 PM

Board # 4351

Impact of Concomitant Deep Vein Thrombosis on Clinical Outcomes in Patients With Acute Pulmonary Embolism

**Shushi Nishiwaki** , The Tazuke Kofukai Medical Res Inst, Kitano Hosp, Osaka, Japan; Yugo Yamashita, Kyoto Univ Graduate Sch, Kyoto, Japan; Yusuke Morita, Moriaki Inoko, The Tazuke Kofukai Medical Res Inst, Kitano Hosp, Osaka, Japan; Takeshi Morimoto, Hyogo Coll Of Med, Nishinomiya, Japan; Hidewo Amano, Kurashiki Central Hosp, Kurashiki, Japan; toru takase, Kinki Univ Hosp, Osaka, Japan; Seiichi Hiramori, Kokura Memorial Hosp, Kitakyushu-shi,Fukuoka, Japan; Kitae Kim, Kobe City Medical Ctr General Hosp, Kobe, Japan; Maki Oi, Japanese Red Cross Otsu Hosp, Otsu, Japan; Takao Kato, Takeshi Kimura, Graduate Sch of Med, Kyoto Univ, Kyoto, Japan

12:30 PM

Board # 4352

Treatment of Limb Ischemia Using Hydrogels With Tunable Mechanical Properties for Endothelial Cell Transplantation

Mahdis Shayan, Riley Suhar, Abbygail Foster, Sarah C Heilshorn, **Ngan F Huang** , Stanford Univ, Stanford, CA

12:30 PM

Board # 4353

Systems Biology of Arteriovenous Fistula to Explore Novel Mechanistic Insights and Therapeutic Targets

**Julius L. Decano** , Caue Gasparotto A Bueno, Gabriela A Quieroz Do-Amaral, LangHo A. Lee, Halu A Arda, Hengmin Zhang, C. Keith Ozaki, Sasha A. Singh, Elena Aikawa, Masanori Aikawa, Brigham and Women's Hosp, Boston, MA

12:30 PM

Board # 4355

Association of Endothelial Dysfunction Measured by Reactive Hyperemia Index With Cardiovascular Risk Factors in Mexican Americans

**Efstratios Koutroumpakis** , UTHealth Science Ctr at Houston, Houston, TX; Craig Hanis, Univ of Texas, houston, TX; David AGUILAR, Univ of Texas Health Science, Houston, TX

12:30 PM

Board # 4356

Temporal Trends and Clinical Course of Deep Vein Thrombosis in Evacuees Post2016 Kumamoto Earthquakes

**Kenji Sakamoto** , Kumamoto Univ Hosp, Kumamoto, Japan; Koji Sato, Kumamoto Univ, Kumamoto, Japan; Yoichiro Hashimoto, Kumamoto City Hosp, Kumamotocity, Japan; Kazuhiko Hanzawa, Niigata Univ, Niigata, Japan; Sunao Kojima, Kawasaki Medical Sch, Okayama, Japan; Daisuke Sueta, Kumamoto Univ Grad Schl Med Sci, Kumamoto, Japan; Koichiro Fujisue, Kumamoto Univ, Kumamoto, Japan; Takeshi Ogo, Natl Cerebral and Cardiovascular Ctr, Osaka, Japan; Hisao Ogawa, Natl Cerebral and Cardiovascular Ctr, Suita Osaka, Japan; Kenichi Tsujita, Seiji Hokimoto, Kumamoto Univ, Kumamoto, Japan

# Abstract Poster Session

## CE.APS.02 - Apoptosis, Necrosis and Autophagy

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 1094

The Anti-Ferroptosis Compount Liproxstatin-1 Protects The Myocardium Against Ishemia/Reperfusion Injury by Decreasing VDAC1 Levels and Increasing in GPX4 Activity

Yansheng Feng, UT Health at San Antonio, San Antonio, TX; Ngonidzashe Benson Madungwe 78229, Nathalie C Tombo 78229, Abdulhafiz Danju Imam Aliagan 78229, **Jean Chrisostome Bopassa** , UTHSCSA, San Antonio, TX

12:30 PM

Board # 1095

Role of Protein Aggregation in Ischemic Cardiomyopathy

**Moydul Islam** , Xiucui Ma, Layla Foroughi, Washington Univ, St. Louis, MO; Babak Razani, Abhinav Diwan, Washington U Sch Med, St Louis, MO; Kartik Mani, Washington Univ, St. Louis, MO

12:30 PM

Board # 1096

Acid Ceramidase Gene Delivery Protects Against Doxorubicin-Induced Cardiotoxicity

**Michele Lai** , Scuola Superiore S'Anna, Pisa, Italy; Giulio Ciucci, Luca Braga, Intl Ctr for Genetic Engineering and Biotechnology, Trieste, Italy; Michele Dei Cas, Riccardo Ghidoni, Rita Paroni, Univ of Milan, Milan, Italy; Simone Vodret, Edoardo Schneider, Intl Ctr for Genetic Engineering and Biotechnology, Trieste, Italy; Mauro Pistello, Univ of Pisa, Pisa, Italy; Francesco Loffredo, Intl Ctr for Genetic Engineering and Biotechnology, Trieste, Italy; Lorena Zentilin, ICGEB, Trieste, Italy; Fabio A Recchia, Temple Univ Sch Med, Philadelphia, PA; Mauro Giacca, ICGEB, Trieste, Italy

12:30 PM

Board # 1097

Deficiency of P62/SQSTM1 Exacerbates Doxorubicin-Induced Cardiac Dysfunction

**Michiko Tsushima** , Junsei Mimura, Jun Liu, Hiromi Yamazaki, Shuya Kasai, Hirofumi Tomita, Ken Itoh, Hirosaki Univ Graduate Sch of Med, Hirosaki, Japan

12:30 PM

Board # 1098

Mitochondrial Quality Control in Atg7-deficient Vsmc Apoe-/- Mice

Hripsime Nahapetyan, Anne-Valerie Cantero, Elisa Grousset, Manon Moulis, Meyer Elbaz, INSERM, Toulouse, France; Wim Martinet, Univ of Antwerp, Antwerp, Belgium; **Cecile Vindis** , INSERM, Toulouse, France

12:30 PM

Board # 1099

Impaired Autophagic Off-rate is Responsible for Cardiac Aging via Oxidative Stress

Yasuko K Bando, **Takahiro Kamihara** , Nagoya Univ, Nagoya Aichi, Japan; Kazuyuki Nishimura, Nagoya Univ Graduate Sch of Med, Nagoya, Japan; Yasheng Retina, Nagoya Univ, Nagoya Aichi, Japan; Toyoaki Murohara, Cardiology, Nagoya Univ, Nagoya, Japan

# Abstract Poster Session

## EA.APS.10 - Atrial Fibrillation Ablation I

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2020

Persistent Atrial Fibrillation as a Dynamic Network of Competing Zones of Control

**Neal Kumar Bhatia** , Albert J Rogers, Stanford Univ, Palo Alto, CA; David Edward Krummen, Univ of California - San Diego, San Diego, CA; Mahmood Alhusseini, Nosheen Moosvi, Chad Brodt, Tina Baykaner, Stanford Univ, Palo Alto, CA; Paul J Wang, Stanford Univ, Stanford, CA; Wouter-Jan Rappel, Univ of California - San DIego, La Jolla, CA; Sanjiv M Narayan, Stanford Med, Stanford, CA

12:30 PM

Board # 2021

Left Atrial Dimension Reduction Rate After Blanking Period Predicts Late Recurrence of Atrial Fibrillation After Radiofrequency Catheter Ablation

**Shunsuke Miyauchi** , Yukiko Nakano, Ikeuchi Yoshihiro, Sho Okamura, Yosaku Okubo, Hironobe Naoya, Takehito Tokuyama, Yasuki Kihara, Graduate Sch of Biomedical Sciences, Hiroshima Univ, Hiroshima, Japan

12:30 PM

Board # 2022

Atrial Fibrillation Ablation and the Risk of Stroke or Transient Ischemic Attack in Patients With Minimal Pre-Ablation Late Gadolinium Enhancement

**Mobin Kheirkhahan** , Matin Goldooz, Univ of Utah, Salt Lake Cty, UT; Alex A Baher, Univ of Utah, Salt Lake City, UT; Alan K Morris, Univ of Utah, Salt Lake Cty, UT; Brent Wilson, Mihail G Chelu, Univ of Utah, Salt Lake City, UT; Nassir F Marrouche, Univ of Utah, Salt Lake Cty, UT

12:30 PM

Board # 2023

Presence of Ablation of Atrial Organized Zones May Predict Response to Ablation

**Albert J Rogers** , Neal K Bhatia, Stanford Univ, Stanford, CA; Mahmood Alhusseini, Stanford Univ, Palo Alto, CA; Nosheen F Moosvi, Stanford Univ, Stanford, CA; Tina Baykaner, Stanford Univ, Palo Alto, CA; Chad Brodt, Paul L Clopton, Paul J Wang, Stanford Univ, Stanford, CA; Wouter-Jan Rappel, UC San Diego, La Jolla, CA; Sanjiv M Narayan, Stanford Med, Stanford, CA

12:30 PM

Board # 2024

Pitfalls in Ultrasound Evaluation of Left Atrial Appendage Mechanical Function Following Its Electrical Isolation

**Carola Gianni** , Javier E Sanchez, Qiong Chen, Domenico G Della Rocca, Bryan C MacDonald, Sanghamitra Mohanty, Chintan Trivedi, Amin Al-Ahmad, Mohamed A Bassiouny, J David Burkhardt, G Joseph Gallinghouse, Rodney P Horton, Patrick M Hranitzky, Luigi Di Biase, Texas Cardiac Arrhythmia Inst, Austin, TX; Jorge Romero, Mario J Garcia, Arrhythmia Services, Montefiore Medical Ctr, Bronx, NY; Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

12:30 PM

Board # 2025

Prediction for Atrial Fibrillation Recurrence After Catheter Ablation Using an Artificial Intelligence-Assisted Coronary Sinus Electrogram

**Zijie Zhang** , Kaibin Lin, Shanghai Jiao Tong Univ affiliated Sixth People's Hosp, Shanghai, China; Zhaorui Zuo, Dahong Qian, Sch of Biomedical Engineering, Shanghai Jiao Tong Univ, Shanghai, China; Yuting Xie, Dong Huang, Jingbo Li, Shanghai Jiao Tong Univ affiliated Sixth People's Hosp, Shanghai, China

12:30 PM

Board # 2027

Obesity and the Risk of Recurrent Atrial Fibrillation Among Patients Who Underwent Pulmonary Vein Isolation: A Systemic Review and Meta-Analysis

**Nath Limpruttidham** , Univ of Hawaii, Honolulu, HI; Tanawan Riangwiwat, Geisinger Health System, Danville, PA; Narut Prasitlumkum, UHIMRP, Honolulu, HI; Pattara Rattanawong, Univ of Hawaii, Honolulu, HI

12:30 PM

Board # 2028

Relation of Left Atrial Volume Index and Cryoballoon Ablation Outcomes for Paroxysmal Atrial Fibrillation

**Abhishek Bose** , Saint Vincent Hosp, Worcester, MA; Parag Anilkumar Chevli, Wake Forest Sch of Med, Winston Salem, NC; Ajay Kumar Mishra, Christian Medical Coll, Vellore, India; Zeba Hashmath, Univ of Pennsylvania, Philadelphia, PA; Gregory Berberian, Jerzy Januszkiewicz, Ghasan Ahmad, Saint Vincent Hosp, Worcester, MA; Douglas Laidlaw, Reliant Medical Group, Worcester, MA

12:30 PM

Board # 2029

Novel Score to Predict Very Late Recurrence of Atrial Fibrillation After Successful Atrial Fibrillation Catheter Ablation

**Yasuyuki Egami** , Osaka Rosai Hosp, Sakai, Japan; Masami Nishino, Osaka Rosai Hosp, Sakai Osaka, Japan; Ryu Shutta, Yasuharu Matsunaga, Osaka Rosai Hosp, Sakai, Japan; Masamichi Yano, 3-1179, Sakai, Japan; Koji Yasumoto, Akihiro Tanaka, Osaka Rosai Hosp, Sakai, Japan; Naotaka Okamoto, Mount Sinai Hosp, New York, NY; Hitoshi Nakamura, Yutaka Matsuhiro, Osaka Rosai Hosp, Sakai, Japan; Daisuke Nakamura, Osaka Univ, Sakai, Japan; Kyosuke Yanagawa, Osaka Rosai Hosp, Sakai-city, Japan; Yamato Masaki, Tanouchi Jun, Osaka Rosai Hosp, Sakai, Japan

12:30 PM

Board # 2030

Convergent Ablation for the Treatment of Long Standing Persistent Atrial Fibrillation - A Single Center Experience

**Syed Rafay Ali Sabzwari** , Lehigh Valley Health Network, Allentown, PA; Lohit Garg, Univ of Pennsylvania, Philadelphia, PA; Nikhil Mehta, James Kimber, Hiwot Ayele, Lehigh Valley Health Network, Allentown, PA; James K Wu, Lehigh Valley Heart and Lung Surgeo, Allentown, PA; Babak Bozorgnia, Lehigh Valley Health Network, Allentown, PA

12:30 PM

Board # 2031

The Real American Experience: Single Center, Single Operator Experience With Visually Guided Laser Balloon Pulmonary Vein Isolation in a Community Hospital

**Rashad Khazi Syed** , Columbia-St Marys Hosp, Milwaukee, WI; Katherine Loveless, Columbia- St Marys Hosp, Milwaukee, WI; Jennifer Gallagher, Kristin Miller, Amy Larson, Christina Rende, Columbia-St Marys Hosp, Milwaukee, WI; Kelly Brock, Columbia-St. Marys Hosp, Milwaukee, WI; Gretta Grube, Sanjay Deshpande, Columbia-St Marys Hosp, Milwaukee, WI

12:30 PM

Board # 2032

Right Angle: Perpendicular Catheter Orientation During Papillary Muscle Ablation Will Result in Larger and Deeper Ablation Lesions

**Duy Nguyen** , Lijun Zheng, Univ Colorado, Aurora, CO; Meg Babakhanian, Paul J Wang, Stanford Univ, Stanford, CA

# Abstract Poster Session

## CE.APS.01 - Cardiomyocytes and Left Ventricular Dysfunction

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 1085

Sarcolipin Ablation Prevents Dystrophic Cardiomyopathy

**Satvik Mareedu** , Rutgers Univ - NJMS, Newark, NJ; Ronald E Pachon, Rutgers Univ, Hopelawn, NJ; Thilagavathi Jayapalraj, Nadezhda Fefelova, Lai-hua Xie, Rutgers Univ - NJMS, Newark, NJ; Gopal J Babu, RUTGERS-NJMS, Newark, NJ

12:30 PM

Board # 1086

Cardiac Microtissue Platform With Dynamically Tunable Afterload Control

**Abhinay Ramachandran** , Carissa Livingston, Univ of Pennsylvania, Philadelphia, PA; Elise Corbin, Univ of Delaware, Newark, DE; Alexia Vite, Alexander Bennett, Kenneth B Margulies, Univ of Pennsylvania, Philadelphia, PA

12:30 PM

Board # 1087

Genetic Manipulations of the Mouse Cardiotonic Steroid Receptor ATP1A1: Impact on Cardiac Resilience Through Modulation of Hypertrophy and Fibrosis

Pauline Marck, Marshall Univ, Huntington, WV; Yunhui Xu, Marshall Inst for Interdisciplinary Res, Huntington, WV; Yanling Yan, Maddie Perdoncin, Cierra King, Qiming Duan, Marshall Univ, Huntington, WV; Jeff Paul McDermott, Univ of Kansas Medical Ctr, Kansas City, KS; Liquan Cai, Marshall Univ, Huntington, WV; Jerry Lingrel, Univ of Cincinnati, Cincinnati, OH; Gustavo V Blanco, Kansas Univ Medical Ctr, Kansas City, KS; Zijian Xie, **Sandrine V Pierre** , Marshall Univ, Huntington, WV

12:30 PM

Board # 1088

Thyroid Hormones Maintain Functional T-Tubule Networks in Cardiomyocytes

**Nimra Gilani** , Kaihao Zhang, NYIT-COM, Old Westbury, NY; Youhua Zhang, New York Inst Technology, Old Westbury, NY; A. Martin Gerdes, NYIT Coll of Osteopathic Med, Old Westbury, NY; Kaie M Ojamaa, New York Inst of Technology, Old Westbury, NY

12:30 PM

Board # 1089

Cardiac Dysfunction Induced by Incretin-Related Drugs Due to Energetic Starvation in Non-Diabetic Failing Heart

**Aya Shiraki** , Junichi Oyama, Koichi Node, Saga Univ, Saga, Japan

12:30 PM

Board # 1090

Sustained Endothelial Dysfunction in the Infarct-related Coronary Artery is Associated With Left Ventricular Adverse Remodeling in Survivors of St-segment Elevation Myocardial Infarction

**Takeo Horikoshi** , Takamitsu Nakamura, Toru Yoshizaki, Yosuke Watanabe, Manabu Uematsu, Juntaro Deyama, Tsuyoshi Kobayashi, Yukio Saito, Kazuto Nakamura, Jyun-Ei Obata, Kiyotaka Kugiyama, Univ of Yamanashi, Chuo, Japan

12:30 PM

Board # 1091

Small Peptide Ac-SDKP Inhibits Radiation-Induced Coronary Endothelial Barrier Disruption by Preserving a Tight-Junction Protein Claudin-1

**Min Chen** , Roswell Park Cancer Inst, Buffalo, NY; Umesh Sharma, Univ at Buffalo, Buffalo, NY; Shirley Xu, Roswell Park Cancer Inst, Buffalo, NY; Swati Sonkawade, Univ at Buffalo, Buffalo, NY; Saraswati Pokharel, Roswell Park Cancer Inst, Buffalo, NY

12:30 PM

Board # 1092

Stress-Induced Remodeling of the Mitral Valve: A Model for Superimposed Tissue Formation in Mitral Valve Prolapse

**Boudewijn P T Kruithof** , Aniek L Van Wijngaarden, Laura Paardekooper, Yasmine L Hiemstra, Marie-José Goumans, Meindert Palmen, Victoria Delgado, Nina Ajmone Marsan, Leiden Univ Medical Ctr, Leiden, Netherlands

12:30 PM

Board # 1093

Chronic Anthrax-Lethal-Toxin Causes Progressive Cardiac Depression in Mice: Insights into Cellular Mechanism

**Zhi Zhang** , Heng-Jie Cheng, Satoshi Masutani, Michael F Callahan, David Zhao, Dalane Kitzman, Che Ping Cheng, Wake Forest Sch of Med, Winston-Salem, NC

# Abstract Poster Session

## HF.APS.20 - Cardiopulmonary Exercise Testing

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2268

Influence of Metabolic Demand on Locomotor Group III/IV Afferents Contribution to Ventilatory Control During Exercise in Heart Failure

**Joshua R Smith** , Michael Joyner, Timothy Curry, Thomas P Olson, Mayo Clinic, Rochester, MN

12:30 PM

Board # 2269

Exercise Stress Test Identifies Preclinical Cardiotoxicity in Pediatric Cancer Survivors With Normal Left Ventricular Function Shown By Echocardiogram

**Takeshi Tsuda** , Daphney Kernizan, Gina D'Aloisio, Joanne Quillen, Alfred I Dupont Hosp for Children, Wilmington, DE

12:30 PM

Board # 2270

Right Ventricle to Pulmonary Circulation Coupling is Primarily Defined by the Circumferential Right Ventricle Function

**Francesco Bandera** , Giacomo D'Alesio, Greta Ghizzardi, Maurizio Losito, Sara Boveri, Eleonora Alfonzetti, Marco Guazzi, IRCCS Policlinico San Donato, Milano, Italy

12:30 PM

Board # 2271

Anaerobic Exercise Reserve as a Predictor of Outcomes in Patients With Heart Failure

Jingyi Gong, Jesse Caron, Renata R Castro, Camden Bay, Jon Hainer, Brigham and Women's Hosp, Boston, MA; Mandeep R Mehra, Brigham and Womens Hosp, Boston, MA; Anju Nohria, Brigham and Women's Hosp, Boston, MA; Marcelo F Di Carli, Bradley A Maron, Brigham and Womens Hosp, Boston, MA; Lynne Warner Stevenson, Vanderbilt Univ Medical Cente, Nashville, TN; **John D Groarke** , Brigham and Women's Hosp, Boston, MA

12:30 PM

Board # 2272

Isolated Knee Extensor Exercise Training Improves Oxygen Uptake Kinetics and Peripheral Oxidative Capacity in HFpEF Patients

**Christopher M Hearon Jr.** , Mitchel Samels, Katrin A Dias, Benjamin D Levine, Satyam Sarma, Inst for Exercise and Environmental Med, Texas Health Presbyterian Dallas and Univ of Texas Southwestern Medical Ctr, Dallas, TX

12:30 PM

Board # 2273

Functional Phenotyping of Heart Failure: Is Left Ventricular Ejection Fraction Categorization Really Useful?

**Marco Guazzi** , Francesco Bandera, IRCCS Policlinico San Donato, San Donato Milanese, Italy; Marta Barletta, IRCCS, Policlinico San Donato, San Donato Milanese, Italy; Maurizio Losito, Valentina Labate, Eleonora Alfonzetti, IRCCS Policlinico San Donato, San Donato Milanese, Italy

12:30 PM

Board # 2274

Atrial Fibrillation is Associated With Impaired Exercise Capacity and Adverse Prognosis in Heart Failure Patients With Mid-range Ejection Fraction

**Yu Sato** , Akiomi Yoshihisa, Yu Hotsuki, Koichiro Watanabe, Yusuke Kimishima, Takatoyo Kiko, Yuki Kanno, Tetsuro Yokokawa, Satoshi Abe, Tomofumi Misaka, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

12:30 PM

Board # 2275

Clinical Factors Associated With Impaired Exercise Cardiac Mechanics in Heart Failure With Preserved Ejection Fraction

**Wendy Ying** , Johns Hopkins Univ Sch of Med, Baltimore, MD; Allison G Hays, Johns Hopkins Univ, Clarksville, MD; Lisa R Yanek, Johns Hopkins Medical Insts, Baltimore, MD; Dhananjay Vaidya, Johns Hopkins Hosp, Baltimore, MD; Vinita Subramanya, Emory Rollins SPH, Atlanta, GA; Megan Bach, Northwestern Univ Feinberg Sch of Med, Chicago; Stephen Dvorak, Sanjiv J Shah, Northwestern Univ, Chicago, IL; Kavita Sharma, Johns Hopkins Univ SOM, Baltimore, MD

12:30 PM

Board # 2276

Sex Differences in Arterial Stiffness Among Patients With HFpEF

**Lindsay G Panah** , Emily S Lau, Mayooran Namasivayam, Elizabeth Liu, John Sbarbaro, Robyn Farrell, Mark Schoenike, Rajeev Malhotra, Matthew G Nayor, Gregory D Lewis, Jennifer E Ho, Massachusetts General Hosp, Boston, MA

# Abstract Poster Session

## EP.APS.13 - Cardiorenal Interactions and Their Implication in CVD Risk Prevention

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 3052

"CKDPatch" to Incorporate Kidney Disease Measures Into the AHA/ACC Pooled Cohort Equation: An International Individual-level Data Study From the CKD Prognosis Consortium (CKD-PC)

**Kunihiro Matsushita** , Johns Hopkins Univ, Baltimore, MD; Simerjot Kaur Jassal, VA San Diego Healthcare System, San Diego, CA; Elke Schaeffner, Charité Univsmedizin Berlin, Berlin; Josef Coresh, Johns Hopkins SPH Welch Ctr, Baltimore, MD; Chronic Kidney Disease Prognosis Consortium

12:30 PM

Board # 3053

Association of Mildly Reduced Estimated Glomerular Filtration Rate With Clinical and Subclinical Cardiovascular Disease and Chronic Kidney Disease: The Framingham Heart Study

**Feven Ataklte** , Boston Medical Ctr, Boston, MA; Rebecca Song, Boston Univ Sch of Public, Boston, MA; Ashish Upadhyay, Boston Medical Ctr, Boston, MA; Vasan S Ramachandran, Framingham Heart Study, Framingham, MA; Vanessa Xanthakis, BU Sch of Med, Boston, MA

12:30 PM

Board # 3054

Patterns of Oral Anticoagulant Treatment Among Non-valvular Atrial Fibrillation Patients With End-stage Renal Disease Treated With Dialysis

Allison Keshishian, STATinMED Res, Ann Arbor, MI; **Daniel Wiederkehr** , Pfizer, Inc., New York, NY; Xiaoyan Li, Bristol-Myers Squibb Company, Lawrenceville, NJ; Jack Mardekian, Pfizer, Inc., New York, NY; Neeraja Balachander, Bristol-Myers Squibb Company, Lawrenceville, NJ; Cristina Russ, Pfizer, Inc., New York, NY; Lisa Rosenblatt, Amol Dhamane, Bristol-Myers Squibb Company, Lawrenceville, NJ; Janvi Sah, STATinMED Res, Ann Arbor, MI; Xuemei Luo, Pfizer, Inc., Groton, CT

12:30 PM

Board # 3055

Influence of Gender and Renal Function Status on In-Hospital Mortality Among Patients With Autosomal Dominant Polycystic Kidney and Cardiovascular Disease in the United States

Omar Chehab, Wayne State Univ-DMC, Detroit, MI; **Mohit Pahuja** , Wayne State Univ, Detroit, MI; Nassib Abou Heidar, American Univ of Beirut Medical Ctr, Beirut, Lebanon; Amjad Kanj, Wayne State Univ / DMC, Detroit, MI; Sagar Ranka, John H Stroger Hosp of Cook Cou, Chicago, IL; Nadine Abdallah, Wayne State Univ / DMC, Detroit, MI; Mohamad Karnib, Case Western Reserve Univ, Cleveland Hts, OH; Mustafa Ajam, Wayne State Univ-DMC, Detroit, MI; Oluwole Adegbala, Englewood hospital and Medical Cent, Bergenfield, NJ; Tushar Mishra, Wayne State Univ / DMC, Detroit, MI; Diane Levine, Wayne State Univ, Detroit, MI; Aiden A Abidov, Wayne State Univ, W Bloomfield, MI

12:30 PM

Board # 3056

The Burden of Cardiovascular Disease Hospitalizations in Patients With End Stage Renal Disease

**Gayatri Pemmasani** , Guntur Medical Coll, Guntur, India; Viswajit Reddy Anugu, Staten Island Univ Hosp, Staten Island, NY; Srikanth Yandrapalli, Westchester Medical Ctr, White Plains, NY

12:30 PM

Board # 3057

Use of Proton Pump Inhibitors Increase Adverse Cardiovascular Events in Hemodialysis Patients: Insight From the KIDS Registry

**Ippei Kosedo** , Akihiro Tokushige, Takuro Takumi, Graduate Sch of Medical and Dental Sciences, Kagoshima Univ, Kagoshima, Japan; Akiko Yoshikawa, Kiyo Teraguchi, Jinaikai Ueyama Hosp, Kagoshima, Japan; Kenichi Takenouchi, Kouzo Shiraishi, Byakkokai Shiraishi Hosp, Kagoshima, Japan; Daisuke Ikeda, Seijinkai Ikeda Hosp, Kanoya, Japan; Masakazu Imamura, Kyosaikai Nanpuh Hosp, Kagoshima, Japan; Takeshi Sonoda, Daisuke Kanda, Yoshiyuki Ikeda, Mitsuru Ohishi, Graduate Sch of Medical and Dental Sciences, Kagoshima Univ, Kagoshima, Japan

12:30 PM

Board # 3058

The HyperK Score is a Powerful Predictor of Incident Hyperkalemia in a Large General Healthcare Population

**Heidi T May** , Intermountain Medical Ctr, Salt Lake City, UT; Jennifer Kammerer, Relypsa, Inc, Redwood City, CA; Tami L Bair, Intermountain Medical Ctr, Salt Lake Cty, UT; Kirk Ute Knowlton, Viet T LE, Jeffrey Lance Anderson, Donald L Lappe, Intermountain Medical Ctr, Salt Lake City, UT; Benjamin D Horne, Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT; Joseph B Muhlestein, Intermountain Medical Ctr; Univ of Utah, Murray, UT

12:30 PM

Board # 3059

Outcomes Associated With Rivaroxaban in Asians With End-stage Renal Disease and Atrial Fibrillation

**Yi-Cheng Lin** , Taipei Medical Univ Hosp, Taipei, Taiwan; Li-Nien Chien, Liying Chen, Taipei Medical Univ, Taipei, Taiwan; Bi-Li Chen, Te-Chao Fang, Chun-Yao Huang, Taipei Medical Univ Hosp, Taipei, Taiwan

12:30 PM

Board # 3060

Association of Kidney Histopathology to Major Adverse Cardiovascular Events in Adults With Chronic Kidney Disease: An Analysis of the Boston Kidney Biopsy Cohort

**Leo F Buckley** , Brigham and Women's Hosp, Boston, MA; Anand Srivastava, Northwestern Univ, Chicago, IL; Afolarin Amodu, Ragnar Palsson, Amil M Shah, Sushrut Waikar, Brigham and Women's Hosp, Boston, MA

12:30 PM

Board # 3061

Continuation of Moderate or High Dose Statin Therapy After Dialysis Transition and Hospitalization Incidence in US Veterans

Christina Park, UC Irvine, Orange, CA; Amber R Cordola Hsu, UC Irvine, Marina del Rey, CA; Jui-Ting Hsiung, UC Irvine, Orange, CA; Melissa Soohoo, UC Irvine, Long Beach, CA; Maria Marroquin, VA Long Beach, Long Beach, CA; Hamid Moradi, Long Beach VA Health Care System, Long Beach, CA; Csaba Kovesdy, Univ of Tennessee Health Science Ctr, Memphis, TN; Kamyar Kalantar-Zadeh, Univ of California Irvine, Orange, CA; **Elani Streja** , Univ of California, Irvine, Orange, CA

12:30 PM

Poster Professor

Chris T Longenecker, Cleveland, OH

# Abstract Poster Session

## EP.APS.10 - Cardiovascular and Brain Health in the Older Population

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 3021

Visit-to-visit Variability of Postural Changes in Systolic Blood Pressure is Associated With Greater Risk of Dementia in Older Black and White Adults

**Laure Rouch** , UCSF, San Francisco, CA; Jean-Sébastien Vidal, EA 4468, Univ Paris Descartes, Sorbonne Paris Cité, Paris, France, Paris, France; Tina Hoang, Northern California Inst for Res and Education, San Francisco, CA; Philippe Cestac, INSERM 1027, Toulouse, France, Toulouse, France; Olivier Hanon, EA 4468, Univ Paris Descartes, Sorbonne Paris Cité, Paris, France, Paris, France; Kristine Yaffe, UCSF, San Francisco, CA

12:30 PM

Board # 3022

Relations of Metabolic Health and Obesity to Brain Aging in Young to Middle-Aged Adults

**Rebecca Angoff** , Beth Israel Deaconess Medical Ctr, Boston, MA; Jayandra J Himali, Boston Univ, Boston, MA; Vasan S Ramachandran, Framingham Heart Study, Framingham, MA; Sudha Seshadri, UT Health San Antonio, San Antonio, TX; Alexa Beiser, Boston Univ, Boston; Connie W Tsao, Beth Israel Deaconess Medical Ctr, Boston, MA

12:30 PM

Board # 3023

Temporal Change in N-terminal Pro-B-type Natriuretic Peptide Level and Risk of Dementia: Multi-ethnic Study of Atherosclerosis (MESA)

**Mohammad R Ostovaneh** , Johns Hopkins Medical Insts, Baltimore, MD; Kasra Moazzami, Emory Univ, Atlanta, GA; Kihei Yoneyama, Bharath Ambale Venkatesh, Johns Hopkins Univ, Baltimore, MD; Susan R Heckbert, Univ of Washington, Seattle, WA; Colin O Wu, Natl Insts of Health, Bethesda, MD; Steven Shea, Columbia Univ, New York, NY; Wendy S Post, Johns Hopkins Univ, Baltimore, MD; Annette L Fitzpatrick, Univ of Washington, Seattle, WA; Gregory Burke, Wake Forest Sch of Med, Winston-Salem, NC; Hossein Bahrami, Keck Sch of Med of USC, Los Angeles, CA; Otto A Sanchez, Univ of Minnesota, Minneapolis, MN; Lori Daniels, UCSD Medical Ctr, Del Mar, CA; Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD; David A Bluemke, UW Madison Hosp, Madison, WI; Joao A Lima, Johns Hopkins Univ, Baltimore, MD

12:30 PM

Board # 3024

Predictors of Healthy Arterial Aging in Persons With Metabolic Syndrome and Diabetes: The Multi-Ethnic Study of Atherosclerosis

**Alexander C. Razavi** , Tulane Univ Sch of Public Health and Tropical Med; Tulane Univ Sch of Med, New Orleans, LA; Nathan D Wong, Univ of California Irvine Sch of Med, Irvine, CA; Matthew J Budoff, Los Angeles Biomedical Res Ctr, Torrance, CA; Lydia A Bazzano, Tulane Univ Sch of Public Health and Tropical Med; Tulane Univ Sch of Med, New Orleans, LA; Tanika N Kelly, Tulane Univ Sch of Public Health and Tropical Med, New Orleans, LA; Jiang He, Camilo Fernandez Alonso, Tulane Univ Sch of Public Health and Tropical Med; Tulane Univ Sch of Med, New Orleans, LA; Joao A Lima, Johns Hopkins Univ Sch of Med, Baltimore, MD; Joseph F. Polak, Tufts Medical Ctr, Boston, MA; Morgana L Mongraw-Chaffin, Wake Forest Sch of Med, Winston Salem, NC; Moyses Szklo, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Alain G Bertoni, Wake Forest Univ Sch of Med, Winston Salem, NC; Roger S Blumenthal, Michael J Blaha, Seamus Paul Whelton, Johns Hopkins Univ Sch of Med, Baltimore, MD

12:30 PM

Board # 3025

The Association Between Hearing and Cognitive Impairment in Atrial Fibrillation Patients: The SAGE-AF Study

**Weijia Wang** , Darleen Lessard, David D McManus, Univ of Massachusetts Medical Sch, Worcester, MA; Jane Saczynski, Northeastern Univ, Boston, MA

12:30 PM

Board # 3026

Accelerated Aortic Stiffening Relative to Carotid Stiffness is Associated With Cognitive Decline: The Whitehall II Study

**Scott T Chiesa** , UCL, London, United Kingdom; Stefano Masi, Univ di Pisa, Pisa, Italy; Martin John Shipley, Univ Coll London, London; Elizabeth Ellins, Swansea Univ, Swansea, KS; Julian P Halcox, Swansea Univ Medical Sch, Swansea; Alan Fraser, Univ of Cardiff, Cardiff, United Kingdom; Alun D Hughes, Riyaz S Patel, UCL, London, United Kingdom; Ashraf William Khir, Brunel Univ, Middlesex, Ukraine; Eric J Brunner, UCL, London, United Kingdom; Archana Singh-Manoux, Inserm, Paris, France; Mika Kivimaki, UCL, London, United Kingdom; David Celermajer, Royal Prince Alfred hospital, Sydney, Australia; John E Deanfield, UCL, London, United Kingdom

12:30 PM

Board # 3027

Visit-to-visit Blood Pressure Variability is Associated With Cognitive Decline and Incident Dementia: The S.AGES Cohort

**Laure Rouch** , EA 4468, Univ Paris Descartes, Sorbonne Paris Cité, Paris, France, Paris, France; Philippe Cestac, INSERM 1027, Toulouse, France, Toulouse, France; Brigitte Sallerin, INSERM 1048, Toulouse, France, Toulouse, France; Linda Benattar-Zibi, ORPEA/ CLINEA, Puteaux, France, Puteaux, France; Philippe Bertin, CHU Limoges, Rhumatologie, Limoges, France, Limoges, France; Gilles Berrut, CHU Nantes, Pôle de Soins Gériatriques, Nantes, France, Nantes, France; Emmanuelle Corruble, Service de Psychiatrie, Hôpital Bicêtre, AP-HP, Le Kremlin-Bicêtre, France, Le Kremlin-Bicêtre, France; Geneviève Derumeaux, Explorations Fonctionnelles Cardiovasculaires, Hôpital Louis Pradel, Hospices Civils de Lyon, Bron, France, Bron, France; Bruno Falissard, INSERM U669, Dept de Biostatistiques, Faculté de médecine Paris-Sud, Le Kremlin-Bicêtre, France; Françoise Forette, Univ René Descartes, Fondation Natle de Gérontologie, Paris, France, Paris, France; Florence Pasquier, CHU Lille, Neurologie, Lille, France, Lille, France; Michel Pinget, Service d'Endocrinologie, Diabète, Maladies de la Nutrition (Pôle NUDE), Hôpitaux Univires de Strasbourg, Strasbourg, France; Rissane Ourabah, Dept de Médecine Générale, Faculté de Médecine Paris-Sud, Univ Paris-Sud, Le Kremlin-Bicêtre, Le Kremlin-Bicêtre, France; Nicolas Danchin, Service de Gériatrie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France., Paris, France; Laurent Becquemont, Hôpital Bicêtre, AP-HP, Le Kremlin-Bicêtre, France, Le Kremlin-Bicêtre, France; Olivier Hanon, Service de Gériatrie, Hôpital Broca, AP-HP, Hôpitaux Univires Paris Ctr, Paris, France; Jean-Sébastien Vidal, Service de Gériatrie, Hôpital Broca, AP-HP, Hôpitaux Univires Paris Ctr,, Paris, France

12:30 PM

Board # 3028

The Impact of Polypharmacy on the Predictive Value of Cognitive Function in Patients With Acute Decompensated Heart Failure; Insights From Osaka Prefectural Acute Heart Failure Registry (OPAR)

**Kiyomi Kayama** , Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masahiro Seo, Osaka General Medical Ctr, Osaka City, Japan; Makoto Abe, Jun Nakamura, Kyoko Yamamoto, Masatsugu Kawahira, Kazuya Tanabe, Osaka General Medical Ctr, Osaka, Japan

12:30 PM

Board # 3029

Atrial Fibrillation is Associated With Greater Risk Of Dementia in Older Veterans

**Laure Rouch** , UCSF, San Francisco, CA; Feng Xia, Northern California Inst for Res and Education, San Francisco, CA; Patrick Stuchlik, Kristine Yaffe, UCSF, San Francisco, CA

12:30 PM

Poster Professor

Sudha Seshadri, San Antonio, TX

# Abstract Poster Session

## EP.APS.09 - Cardiovascular Disease Among Minority and Vulnerable Populations

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 3011

Improving Cardiovascular Risk Prediction in Asian Subgroups

**Rishi V Parikh** , Kaiser Permanente Northern California, Oakland, CA; Jamal S Rana, Kaiser Permanente, Oakland, CA; Thida C Tan, Kaiser Permanente Northern California, Oakland, CA; Seema K Pursnani, Kaiser Permanente, Santa Clara, CA; Neha M Mantri, Kaiser Permanente Northern California, San Francisco, CA; Alan S Go, Kaiser Permanente Northern Cal, Oakland, CA

12:30 PM

Board # 3012

Validity of Self Reported Cardiovascular Disease Risk Factors in African American Adults

**Ahsan R Khan** , Jeong Hwan Kim, Kiran Ejaz, Emory Univ, Atlanta, GA; Matthew L Topel, Emory Univ Sch of Med, Atlanta, GA; Peter Baltrus, Morehouse Sch of Med, Atlanta, GA; Chang Liu, Yi-An Ko, Emory Univ, Atlanta, GA; Mahasin S Mujahid, UC Berkeley, Berkeley, CA; Viola Vaccarino, Emory Univ Rollins Schl Public Hlth, Atlanta, GA; Mario Sims, Univ Mississippi Medical Ctr, Jackson, MS; Charles D Searles, Sandra B Dunbar, Emory Univ, Atlanta, GA; Priscilla Eyikojoka Pemu, Morehouse Sch of Med, Atlanta, GA; Tene T Lewis, Emory Univ, Atlanta, GA; Herman A Taylor, Morehouse Sch Med, Atlanta, GA; Arshed A Quyyumi, Emory Univ, Atlanta, GA

12:30 PM

Board # 3013

Variances of Cardiovascular Risk Factors Among Asian Subgroups, National Health Interview Survey 2014-2017

**Murrium I. Sadaf** , Yale-New Haven Medical Ctr (Waterbury) Program, Waterbury, CT; Rohan Khera, UT Southwestern Medical Ctr, Dallas, TX; Gowtham Grandhi, Yale Univ, New Haven, CT; Salim S Virani, Michael E Debakey VA-Baylor, Bellaire, TX; Khurram Nasir, Baptist Health South Florida, New Haven, CT; Javier Valero-Elizondo, Yale Sch of Med, New Haven, CT

12:30 PM

Board # 3014

Impact of Polysubstance Use on Markers of Cardiovascular Disease in Homeless and Unstably Housed Women

**Elise D. Riley** , Eric Vittinghoff, Univ of CA, San Francisco, San Francisco, CA; Alan H.B. Wu, Univ of California, San Francisco, CA; Phillip O. Coffin, San Francisco Dept of Public Health, San Francisco, CA; Dhruv Kazi, Harvard Univ, Boston, MA; Priscilla Y. Hsue, Univ of California, San Francisco, CA; Kara L. Lynch, Univ of CA, San Francisco, San Francisco, CA

12:30 PM

Board # 3015

Sociodemographic Disparities in Awareness of Heart Attack Symptoms in the United States

**Shiwani Mahajan** , Yale Sch of Med, New Haven, CT; Javier Valero Elizondo, Yale Univ, New Haven, CT; Rohan Khera, UT Southwestern Medical Ctr, Dallas, TX; Nihar R. Desai, Yale Sch of Med, New Haven, CT; Ron Blankstein, Brigham and Women's Hosp, Boston, MA; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; Salim S Virani, Michael E. DeBakey VA-Baylor, Bellaire, TX; Bita A. Kash, Houston Methodist Res Inst, Houston, TX; Harlan M Krumholz, Khurram Nasir, Yale Sch of Med, New Haven, CT

12:30 PM

Board # 3016

Insurance Disparity in Cardiovascular Mortality Among Early Stage, Non-elderly Cancer Survivors in the US

**Tiantian Shi** , Bridgeport Hosp/Yale New Haven Health, Bridgeport, CT; Changchuan Jiang, Icahn Sch of Med at Mount Sinai, Mount Sinai St lukes and Mount Sinai West Hosp, New York, NY; Stuart W Zarich, Bridgeport Hosp, Bridgeport, CT

12:30 PM

Board # 3017

Electronic Health Record Intervention Improves Hypertension Management in Immigrant-Serving Primary Care Practices

**Priscilla Lopez** , NYU Langone Health, New York, NY; Anna Divney, CUNY Graduate Sch of Public Health and Health Policy, New York, NY; Jennifer Zanowiak, NYU Langone Health, New York, NY; Project IMPACT Providers and Staff; Rashi Kumar, Ronald Sanchez, Susan Beane, Healthfirst, New York, NY; Lorna Thorpe, Nadia Islam, NYU Langone Health, New York, NY

12:30 PM

Board # 3018

Branched Chain and Aromatic Amino Acids are Associated With Cardiometabolic Risk Among Older Puerto Ricans

**Shilpa N Bhupathiraju** , Harvard Medical Sch, Boston, MA; Megu Y Baden, Harvard Sch of Public Health, Boston, MA; Kathryn M Rexrode, Brigham and Women's Hosp, Boston, MA; Katherine L Tucker, Univ of Massachusetts Lowell, Lowell, MA; Frank Hu, Harvard Sch of Public Health, Boston, MA; Clary B Clish, Broad Inst of MIT and Harvard, Cambridge, MA; Liming Liang, Harvard Univ, Boston, MA; JoAnn E Manson, Harvard Medical Sch, Boston, MA

12:30 PM

Board # 3019

Cardiometabolic Risk and Endothelial Dysfunction in Mexican Americans

**James R Stone** , Danielle M Stone, McGovern Medical Sch at UTHealth, Houston, TX; Miryoung Lee, UTHealth, Sch of Public Health, Brownsville, TX; Susan T Laing, Beverly Smulevitz, McGovern Medical Sch at UTHealth, Houston, TX; Susan P Fisher-Hoch, Joseph B McCormick, UTHealth, Sch of Public Health, Brownsville, TX; David D McPherson, Enrique D Garcia-Sayan, McGovern Medical Sch at UTHealth, Houston, TX

12:30 PM

Board # 3020

Smoking Patterns and High-risk Behavior Among Lesbian, Gay, and Bisexual Adults: The Behavioral Risk Factor Surveillance System (brfss) Survey

**Mahmoud Al Rifai** , Baylor Coll of Med, Houston, TX; Mohammadhassan Mirbolouk, Johns Hopkins Medical Inst, Baltimore, MD; Xiaoming Jia, Baylor Coll of Med, Houston, TX; Khurram Nasir, Baptist Health South Florida, New Haven, CT; Vijay Nambi, Baylor Coll of Med, Sugar Land, TX; Christie M Ballantyne, Baylor Coll of Med, Houston, TX; Anwar T. Merchant, Arnold Sch of Public Health, Univ of South Carolina, Columbia, SC; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; Salim S Virani, Michael E Debakey VA-Baylor, Bellaire, TX

12:30 PM

Poster Professor

Alka M Kanaya, San Francisco, CA

# Abstract Poster Session

## EP.APS.12 - Cardiovascular Disease Epidemiology Across the Globe

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 3042

Global Burden of Rheumatic Heart Disease and the Shortage of Penicillin

**Vikas Yellapu** , Qasim Z Malik, St.Luke's Univ Health Network, Bethlehem, PA; Ileana Perez Figueroa, St.Luke's Univ Health Network-Anderson, Easton, PA; Avi Singh, Santo V Longo, Sudip Nanda, St.Luke's Univ Health Network, Bethlehem, PA

12:30 PM

Board # 3043

Status of Dyslipidemia and Associated Risk Factors in Eastern China

Wei Yu, Shiyun Hu, Xiaoling Xu, Jing Yan, Fang Ding, Xuan Chen, Meifang Su, Zhenjun Lou, Qiuliang Zhu, Zhenping Hu, Junfei He, Jianling Shao, Zhejiang Hosp, Hangzhou, China; **Zugui Zhang** , Christiana Care Health System, Newark, DE

12:30 PM

Board # 3044

Towards Elimination of Rheumatic Heart Disease: Lessons From the 2017 Global Burden of Disease Study

**Kathleen N Fenton** , Natl Heart, Lung and Blood Inst, Bethesda, MD; Simon Yadgir, Inst for Health, Seattle, WA; Catherine Johnson, David Watkins, Univ of Washington, Seattle, WA; Gregory A Roth, Univeristy Washington, Seattle, WA; George A Mensah, NIH, NHLBI, Bethesda, MD

12:30 PM

Board # 3045

The Prevalence of Acute Myocardial Infarction Among Emergency Department Patients in Northern Tanzania

**Julian T Hertz** , Duke Univ, Durham, NC; Francis M Sakita, Kilimanjaro Christian Medical Ctr, Moshi, Tanzania, United Republic of; Godfrey L Kweka, Kilimanjaro Christian Res Inst, Moshi, Tanzania, United Republic of; Sophie W Galson, Alex T Limkakeng Jr., Jinny Ye, Duke Univ, Durham, NC; Gloria Temu, Kilimanjaro Christian Medical Ctr, Moshi, Tanzania, United Republic of; John A Bartlett, Janet P Bettger, Duke Univ, Durham, NC; Gerald S Bloomfield, Duke Univ Medical Ctr, Durham, NC

12:30 PM

Board # 3046

National Survey With Over 800 000 Adults Reveals State-Wide Variation and High Level of Uncontrolled Hypertension in India

**Ming Kei Chung** , Kajal Claypool, Chirag Patel, Harvard Univ, Boston, MA

12:30 PM

Board # 3047

Epidemiologic Features of Heart Failure Patients in Rural Central India

Abhisake Kole, Jan Swasthya Sahyog, Bilaspur, India; Bhavna Seth, Sukhmeet Sandhu, Boston Univ Medical Ctr, Boston, MA; Anup Agarwal, Jan Swasthya Sahyog, Bilaspur, India; Bassem Ghali, Univ of California, San Francisco, San Francisco, CA; Puneeta Arya, Massachusetts General Hosp, Boston, MA; Sushil Patil, Jan Swasthya Sahyog, Bilaspur, India; **Gene Kwan** , Boston Univ Sch of Med, Boston, MA

12:30 PM

Board # 3049

Fuster-bewat Score versus Cardiovascular Health Score to Predict Subclinical Target Organ Damage: Insights From a Large-scale Asian Population

**Haoyu Wang** , Kefei Dou, Dept of Cardiology, Fuwai Hosp, Natl Ctr for Cardiovascular Diseases, Chinese Acad of Medical Sciences & Peking Union Medical Coll, Beijing, China

12:30 PM

Board # 3050

Causes and Comorbidities of Hospitalized Heart Failure in 8 Countries

**Sophia Emmons-Bell** , Inst for Health Metrics and Evaluation, Seattle, WA; Catherine Johnson, Univ of Washington, Seattle, WA; Simon Yadgir, Inst for Health, Seattle, WA; Spencer James, Univ of Washington, Seattle, WA; Gregory A Roth, Univ Washington, Seattle, WA

12:30 PM

Board # 3051

Treatment Pathways of Oral Anticoagulants for Stroke Prevention in Atrial Fibrillation Patients - Clinical Landscape From Multiple Countries

**Pareen Vora** , Bayer AG, Berlin, Germany; Henry Morgan Stewart, IQVIA, Brighton, United Kingdom; Beth Russell, Alex Asiimwe, Bayer AG, Berlin, Germany; Gunnar Brobert, Bayer AB, Stockholm, Sweden

12:30 PM

Poster Professor

Dorairaj Prabhakaran, Gurgaon, India

# Abstract Poster Session

## QU.APS.04 - Clinical Guidelines and Quality Improvement

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 3241

Successes and Ongoing Opportunities in National Efforts to Improve STEMI Care: Mission: Lifeline Update 2010-2018

**Murtuza J Ali** , Louisiana State Univ Sch Med, New Orleans, LA; Patricia J Best, Mayo Clinic, Rochester, MN; Mark Bieniarz, New Mexico Heart Inst, Albuquerque, NM; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; William J French, Harbor-UCLA Medical Ctr, Torrance, CA; John Gallagher, Wichita/Sedgwick County EMS, Wichita, KS; Abhinav Goyal, Emory Sch of Med, Atlanta, GA; Christopher Granger, Duke Univ, Durham, NC; Timothy D Henry, Cedars Sinai Medical Ctr, Cincinnati, OH; Lori Hollowell, American Heart Association, Summerville, SC; James Jollis, Duke Univ, Durham, NC; John Kelly, Albert Einstein Medical Ctr, Philadelphia, PA; Michael Redlener, Mt. Sinai, New York, NY; Harper Stone, Jackson Heart Clinic, Jackson, MS; Jessica Zegre-hemsey, UNC Chapel Hill, Chapel Hill, NC; Alice K Jacobs, Boston Univ Medical Cent, Boston, MA

12:30 PM

Board # 3242

Implementation of an Accelerated Pathway for Chest Pain Evaluation Leads to Early Detection of Acute Coronary Syndromes Earlier and Reduced Length of Stay

**Yitzchak Weinberger** , NYU Langone Medical Ctr, New York, NY; Gregory Katz, New York, NY; Adriana Quinones-Camacho, Andrew Armanious, John A Bostrom, Samuel J Kozloff, NYU Langone Medical Ctr, New York, NY; Christina DiStefano, NYU Langone Health, New York, NY; Christopher Caspers, NYU Langone Medical Ctr, New York, NY

12:30 PM

Board # 3243

Multi-Level and Multifactorial Barriers to Implementation of Guideline Directed Syncope Care Substantially Increases Resource Utilization With Dramatic Impact on Potential Cost

**Vedant Gupta** , Amy Cowley, Hilary Surratt, Univ of Kentucky, Lexington, KY; Susan S Smyth, Univ of Kentucky, Lexington; Matthew Sirrine, Hanwen Yuan, Jing Li, Univ of Kentucky, Lexington, KY

12:30 PM

Board # 3244

Impact of 2017 American Heart Association Guidelines on Cardiac Telemetry Utilization: Study From a Tertiary Medical Center

**Anusha Ganapati Bhat** , Ryan Quarles, Kanval Shah, Lisa Demko, Sandeep Muddasani, Kathleen Mahoney, Lotfi Amir, Joseph Schmidt, Alicia Meacham, Crystal Wilson, Carlo Reale, Mihaela Stefan, Baystate Medical Ctr, Springfield, MA

12:30 PM

Board # 3245

True or False? Clinical Experience in Reduction of False Positive Events With Second Generation of Wireless Insertable Cardiac Monitors

**Esteban M Kloosterman** , Boca Raton Regional Hosp, Boca Raton, FL; Murray Rosenbaum, Eric Berkowitz, Cardiac Arrhythmia Service, Boca Raton, FL; Jonathan Rosman, Boca Raton Regional Hosp, Boca Raton, FL

12:30 PM

Board # 3246

Are Primary Care Providers Meeting Guidelines for Stroke Prevention in Atrial Fibrillation?

**Jafna Layth Cox** , Ratika Parkash, QEII Health Sciences Ctr, Halifax, NS, Canada; Laura Hamilton, Nova Scotia Health Authority, Halifax, NS, Canada; Lehana Thabane, Gary Foster, McMaster Univ, Hamilton, ON, Canada; James MacKillop, NSHA, Sydney, NS, Canada; Feng Xie, McMaster Univ, Hamilton, ON, Canada; Antonio Ciaccia, Bayer Inc., Mississauga, ON, Canada; Shurjeel Choudhri, Bayer, Mississauga, ON, Canada; Joanna Nemis-White, Strive Health, Hammonds Plains, NS, Canada

12:30 PM

Board # 3247

Underutilization of Oral Anticoagulant Therapy in At-Risk Patients With Atrial Fibrillation—Insights From a Multistate Healthcare System

**Ty J Gluckman** , Providence Heart Inst, Portland, OR; Amir Ali, Providence St. Joseph Health, Portland, OR; Mansen Wang, Providence Heart Inst, Portland, OR; Howard Mun, Providence St. Joseph Health, Portland, OR; Sally Alfred, John Louis Petersen II, Swedish Medical Ctr, Seattle, WA

12:30 PM

Board # 3248

Opportunities to Improve the Efficacy and Safety of Oral Anticoagulant Therapy in Atrial Fibrillation—Insights From a Multistate Healthcare System

**Ty J Gluckman** , Providence Heart Inst, Portland, OR; Amir Ali, Providence St. Joseph Health, Portland, OR; Mansen Wang, Providence Heart Inst, Portland, OR; Howard Mun, Providence St. Joseph Health, Portland, OR; Sally Alfred, John Louis Petersen II, Swedish Medical Ctr, Seattle, WA

12:30 PM

Board # 3249

**Clinicians for** Care **: How a Systematic Literature Review Informs Clinicians on Engaging Caregivers as Part of the Cardiovascular Care Team**

**Kellen A Knowles** , Helen Xun, Sun Young Jang, Rohanit Singh, Sharon Pang, Johns Hopkins Univ Sch of Med, Baltimore, MD; Rongzi Shan, Johns Hopkins Sch of Med, Baltimore, MD; Francoise A. Marvel, Seth S Martin, Johns Hopkins Hosp, Baltimore, MD

12:30 PM

Board # 3250

Leveraging the Electronic Health Records for Population Health: A Case Study of Patients With Severe Hypertension

**Yuan Lu** , Chenxi Huang, Shiwani Mahajan, Erica S Spatz, Wade Schulz, Harlan M Krumholz, Yale Univ, New Haven, CT

# Abstract Poster Session

## SA.APS.07 - Clinical Outcomes in Heart Failure and Transplant

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4273

Machine Learning Discovery of the Patterns and Impact of Recurrent Bleeding in Patients With Left Ventricular Assist Devices

**Laura Seese** , Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Faezeh Movahedi, Univ of Pittsburgh, Pittsburgh, PA; Sarah Burki, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; James F Antaki, Cornell Univ, Ithaca, NY; Arman Kilic, Univ of Pittsburgh, Pittsburgh, PA; Manreet Kanwar, Allegheny General Hosp, Pittsburgh, PA; Christopher Sciortino, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Robert L Kormos, Univ Pittsburgh Medical Ctr, Pittsburgh, PA

12:30 PM

Board # 4274

Early RHF Post Tricuspid Valve Repair Performed Concurrent With LVAD Implantation is Not Associated With Late RHF

**Yaron Barac** , Duke Medical Ctr, Durham, NC; Muath Bishawi, Alina Nicoara, Duke Univ, Durham, NC; Jacob Schroder, Joseph G Rogers, Duke Univ Medical Ctr, Durham, NC; Chetan B Patel, Duke Univ, Durham, NC; Mani Daneshmand, Emory Univ, Atlanta, GA; Nazish K. Hashmi, Duke Medical Ctr, Durham, NC; Eric Jose Velazquez, Yale Univ Sch of Med, New Haven, CT; Carmelo A Milano, Duke Univ, Durham, NC

12:30 PM

Board # 4275

Regional Variability in Heart Transplant Rates Across US Impacts Blood Type O Recipients

**Furqan A Rajput** , Univ of Wisconsin-Madison, Madison, WI; Jason Smith, Univ of Wisconsin, Madison, WI; Timothy Hess, David Pham, Aurangzeb Baber, Univ of Wisconsin-Madison, Madison, WI; Amy Fiedler, Univ of Wisconsin, Madison, WI; Farhan Raza, Univ of Wisconsin-Madison, Madison, WI; David Murray, William S Middleton Memorial VA; Ravi Dhingra, Univ of Wisconsin-Madison, Madison, WI

12:30 PM

Board # 4276

Surgical Ablation for Atrial Fibrillation in Hypertrophic Cardiomyopathy: Outcomes of a Tailored Approach

**Kevin Hodges** , Andrew Tang, Carlos Godoy, Cleveland Clinic, Cleveland, OH; Milind Desai, Cleveland Clinic, Solon, OH; Marc Gillinov, Nicholas G Smedira, Per Wierup, Cleveland Clinic, Cleveland, OH

12:30 PM

Board # 4277

New Heart Transplant Allocation Tier System and Clinical Outcomes

**Andrew Pistner** , Univ of Wisconsin-Madison, Madison, WI; Jason Smith, Univ of Wisconsin, Madison, WI; Timothy Hess, David Pham, Aurangzeb Baber, Amy Fiedler, Farhan Raza, David Murray, Ravi Dhingra, Univ of Wisconsin-Madison, Madison, WI

12:30 PM

Board # 4278

Heart Transplant Candidates Listed at Low First-Rank Organ Acceptance Rate Centers Are More Likely to Die Waiting

**Ashley Y Choi** , Duke Univ Sch of Med, Durham, NC; Michael S Mulvihill, Duke Univ Medical Ctr, Durham, NC; Hui-Jie Lee, Congwen Zhao, Maragatha Kuchibhatla, Duke Univ, Durham, NC; Christopher B Granger, Matthew G Hartwig, Duke Univ Medical Ctr, Durham, NC

12:30 PM

Board # 4279

Surgical Left Atrial Appendage Exclusion Improves Outcomes in Patients With Atrial Fibrillation Undergoing Coronary Artery Bypass Surgery

Edward G Soltesz, **Krish C Dewan** , Cleveland Clinic, Cleveland, OH; Louise H Anderson, Technomics Res, LLC, Medina, MN; Michael A Ferguson, Atricure, Minnetonka, MN; Marc Gillinov, Cleveland Clinic, Cleveland, OH

12:30 PM

Board # 4281

Survival in Combined Heart-Liver Transplantation is Superior to Heart Transplantation Alone in Patients With Significant Liver Dysfunction

**Daniel Rinewalt** , Stanford Univ, Palo Alto, CA; John W MacArthur, Standford Univ, Palo Alto, CA; Yuanjia Zhu, Stanford Univ, Palo Alto, CA; Maria Currie, Stanford, Stanford, CA; Anson M Lee, tanford Univ, Stanford, CA; Jack H Boyd, Stanford Univ SOM, Stanford, CA; William Hiesinger, Stanford Univ Sch Of Med, Stanford, CA; Bharathi Lingala, Stanford Univ, Stanford, CA; Yasuhiro Shudo, Stanford Univ, Menlo Park, CA; Y Joseph Y Woo, Stanford Univ Sch Med, Stanford, CA

12:30 PM

Poster Professor

Filio Billia, Toronto, ON, Canada

# Abstract Poster Session

## EP.APS.08 - Cohort Studies I

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 3000

Distribution of Microvascular Endothelial Function in Different Clinical and Non-Clinical Settings in the United States and China

Leila Messahli, Endothelix, Houston, TX; Yasamin Naghavi, Ahmed Gul, Maha Gul, Ruoyu Zhuang, Univ of Houston, Houston, TX; Albert Yen, Endothelix, Houston, TX; Hirofumi Tanaka, Univ of Texas Austin, Austin, TX; Ralph Metcalfe, Stanley Kleis, Univ of Houston, Houston, TX; **Morteza Naghavi** , SHAPE, Palo Alto, CA

12:30 PM

Board # 3001

Intra- and Inter-Individual Changes in Daily Resting Heart Rate Over Two Years for 92,457 Individuals

**Giorgio Quer** , Scripps Res, La Jolla, CA; Pishoy Gouda, Univ of Alberta, Edmonton, AB, Canada; Michael Galarnyk, Eric J Topol, Scripps Res, La Jolla, CA; Steven R Steinhubl, Scripps Res, Lajolla, CA

12:30 PM

Board # 3002

Clinical Outcomes of Perioperative Takotsubo Cardiomyopathy Associated With Noncardiac Surgery

**Yusuke Morita** , Yuhei Yamaji, Eisaku Nakane, Yoshisumi Haruna, Tetsuya Haruna, Michiya Hanyu, Moriaki Inoko, Kitano Hosp, Osaka, Japan

12:30 PM

Board # 3003

Change in Body Mass Index and Long-term Risk of Stroke in Healthy Men

**Erik Prestgaard** , Julian Mariampillai, Kristian Engeseth, Per Torger Skretteberg, Jan Eriksson, Johan Bodegard, Oslo Univ Hosp Ullevål, Oslo, Norway; Knut Liestøl, Univ of Oslo, Oslo, Norway; Sverre E Kjeldsen, Irene Grundvold, Eivind Berge, Oslo Univ Hosp Ullevål, Oslo, Norway

12:30 PM

Board # 3004

The Relationships of Serum Thrombospondin2 With N-terminal Pro-brain Natriuretic Peptide and Insulin Resistance Are Strongest in the Serum Thrombospondin2 Pathological Range

**Nagisa Morikawa** , David R. Jacobs Jr., Univ of Minnesota, Minneapolis, MN; Hisashi Adachi, Kurume Univ Sch of Med, Kurume-shi, Japan; Mika Enomoto, Ako Fukami, Yoshihiro Fukumoto, Kurume Univ Sch of Med, Kurume, Japan

12:30 PM

Board # 3005

Global Prevalence of Cardiogenic Shock in Patients With Takotsubo Cardiomyopathy: A Systematic Review and Meta-Analysis of 77,537 Patients

Rupak Desai, Atlanta VA Medical Ctr, Decatur, GA; **Tarang Parekh** , George Mason Univ, Fairfax, VA; Ankit Vyas, Inova Heart and Vascular Inst, Falls Church, VA; Constance Owens, George Mason Univ, Fairfax, VA; Mir Zeeshan Ali Khan, St. Peters Univ Hosp, New Brunskwick, NJ; Nazia Farheen, Lake America Family Physicians, Clermont, FL; Abhimanyu Ravalani, St Peters Univ Hosp, New Brunswick, NJ; Kishor Gangani, Texas Health Arlington Memorial, Arlington, TX; Rajesh Sachdeva, Morehouse Univ Sch of Med & Atlanta VA Medical Ctr, Atlanta, GA; Gautam Kumar, Emory Univ & Atlanta VA Medical Ctr, Decatur, GA

12:30 PM

Board # 3006

Patterns of Oral Anticoagulant Treatments After Major Gastrointestinal Bleeding Among Nonvalvular Atrial Fibrillation Patients

Steve Deitelzweig, Ochsner Clinic Fndn, New Orleans, LA; Allison Keshishian, STATinMED Res, Ann Arbor, MI; Amiee Kang, **Amol Dhamane** , Bristol-Myers Squibb Company, Lawrenceville, NJ; Xuemei Luo, Pfizer, Inc., Groton, CT; Neeraja Balachander, Lisa Rosenblatt, Bristol-Myers Squibb Company, Lawrenceville, NJ; Jack Mardekian, Pfizer, Inc., New York, NY; Jenny Jiang, Bristol-Myers Squibb Company, Lawrenceville, NJ; Huseyin Yuce, New York City Coll of Technology, New York, NY; Gregory Y.H. Lip, Liverpool Ctr for Cardiovascular Science, Univ of Liverpool and Liverpool Heart & Chest Hosp, Liverpool, United Kingdom

12:30 PM

Board # 3007

Clinical Characteristics of Triglycerides Slope Among Rapid Egfr Decliners

Melissa Soohoo, VA Long Beach, Long Beach, CA; Jui-Ting Hsiung, Christina Park, UC Irvine, Orange, CA; Maria Marroquin, VA Long Beach, Long Beach, CA; Hamid Moradi, Long Beach VA Health Care System, Long Beach, CA; Csaba Kovesdy, Univ of Tennessee Health Science Ctr, Memphis, TN; Kamyar Kalantar-Zadeh, Univ of California Irvine, Orange, CA; **Elani Streja** , Univ of California, Irvine, Orange, CA

12:30 PM

Board # 3008

Statins are Associated With a Lower Risk of All-Cause Mortality in Veterans With Heart Failure With Preserved Ejection Fraction

**Ariela R Orkaby** , VA Boston Healthcare System, Brigham & Women's Hosp, Harvard Medical Sch, Boston, MA; Brian Charest, Katherine Kurgansky, David Gagnon, VA Boston Healthcare System, Boston, MA; Luc Djousse, BWH and Harvard Med Sch, Boston, MA; Jacob Joseph, VA Boston Brigham Womens Hosp, Boston, MA

12:30 PM

Board # 3009

Factors Associated With Providers Instructing US Adults to Take Aspirin Who Have Hypertension and Diabetes Mellitus: The National Health and Nutrition Examination Survey 2015-2016

**Joel C Marrs** , Sarah L Anderson, Univ Colorado Anschutz Medical Campus, Aurora, CO

12:30 PM

Board # 3010

The Correlation Between Renin Angiotensin Aldosterone System Blockers and Future Osteoporotic Fractures in a Hypertensive Population - A Population-based Cohort Study in Taiwan

**Yung-Ta Kao** , Chun-Yao Huang, Taipei Medical Univ Hosp, Taipei City, Taiwan; Yu-Ann Fang, Ju-Chi Liu, Shuang Ho Hosp, New Taipei City, Taiwan

# Abstract Poster Session

## IM.APS.07 - Echocardiography: Function and Dysfunction

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4071

Echocardiographic Characteristics of Patients With Heart Failure and Preserved Ejection Fraction: Noninvasive Assessment by 3-dimensional Speckle Tracking Echocardiography

**Shingo Minatoguchi** , Gifu Univ Graduate Sch of Med, Gifu, Japan; Takashi Yoshizane, Gifu Pefectural General Medical Ctr, Gifu, Japan; Ryuhei Tanaka, Asahi Univ Hosp, Gifu, Japan; Koji Ono, Gifu Prefectural General Medical Ctr, Gifu, Japan; Hidemaro Sato, Sawada Hosp, Gifu, Japan; Maki Nagaya, Hirotaka Miwa, Makoto Iwama, Toshiyuki Noda, Gifu Prefectural General Medical Ctr, Gifu, Japan; Masanori Kawasaki, Gifu Heart Ctr, Gifu, Japan; Hiroyuki Okura, Gifu Univ Graduate Sch of Med, Gifu, Japan

12:30 PM

Board # 4073

Effects of Moderate Alcohol Ingestion on Cardiac Electromechanical Properties in Asia-Specific Aldehyde Dehydrogenase 2 Deficiency Mice

An-Sheng Lee, **Chung-lieh Hung** , Cheng-huang Su, Hung-I Yeh, MacKay Memorial Hosp, Taipei City, Taiwan

12:30 PM

Board # 4074

Hypertensive Diseases in Pregnancy, Cardiac Structure and Function Later in Life: Insights From the Genetic Epidemiology Network of Arteriopathy Study

**Adebamike A Oshunbade** , Arsalan Hamid, Seth T Lirette, Univ of Mississippi Medical Ctr, Jackson, MS; Semiu O Gbadamosi, Florida Intl Univ, Miami, FL; Martin Tibuakuu, St. Luke's Hosp, Ballwin, MO; Olusola Orimoloye, Johns Hopkins Univ, Baltimore, MD; Donald Clark III, Univ of Mississippi, Jackson, MS; Daisuke Kamimura, Yokohama City Univ Hosp, Yokohama, Japan; Wondwosen K Yimer, Univ of Mississippi Medical Ctr, Jackson, MS; Stephen D Grado, Univ of Mississippi Sch of Med, Jackson, MS; Elizabeth A Lutz, Univ of Mississippi Medical Ctr, Jackson, MS; Robert J Mentz, Duke Clinical Res Inst, Hillsborough, NC; Ervin R Fox, Javed Butler, Kenneth R Butler Jr., Thomas H Mosley Jr, Michael E Hall, Univ of Mississippi Medical Ctr, Jackson, MS

12:30 PM

Board # 4075

The Impact of Age And Gender on Left Ventricular Stroke Volume in Healthy Adults From the World Alliance of Societies of Echocardiography (WASE) Normal Values Study

**Tatsuya Miyoshi** , Medstar Health Res Inst, Washington, DC; Karima Addetia, Univ of Chicago, Chicago, IL; Alexandra Blitz, TOMTEC Imaging Systems GmbH, Unterschleissheim, Germany; Roberto M Lang, Univ of Chicago, Chicago, IL; Federico M Asch, MedStar Health Res Inst, Washington, DC; the WASE Investigators

12:30 PM

Board # 4076

Predicting Clinical Outcomes of Inpatients With Heart Failure Based on Echocardiogram Reports Using Natural Language Processing and Deep Learning Models

**Talal Alzahrani** , George Washington Univ, Arlington, VA; Brian Choi, George Washington Univ, Washington, DC; Joseph Krepp, The George Washington Univ, Washington, DC; Jannet F Lewis, George Washington Univ Medical Ctr, Washington, DC

12:30 PM

Board # 4077

Clinical Utility of Left Atrial Strain to Predict Functional Recovery in Patients With Optimal Treatments of Heart Failure

**Yuta Torii** , Kenya Kusunose, Yamada Nao, Okushi Yuichiro, Takahashi Tomonori, Morita Sae, Yukina Hirata, Susumu Nishio, Hirotsugu Yamada, Masataka Sata, Tokushima Univ Hosp, Tokushima, Japan

12:30 PM

Board # 4078

Prognostic Value of Diastolic Late Mitral Annular Velocity Measured by Echocardiography in Heart Failure With Preserved Left Ventricular Ejection Fraction

**Eiichiro Yamamoto** , Kumamoto Univ Hosp, Kumamoto, Japan; Fumi Oike, Kumamoto Univ Hosp, Kumamoto city, Japan; Taiki Nishihara, Masafumi Takae, Kumamoto Univ Hosp, Kumamoto, Japan; Koichiro Fujisue, Kumamoto Univ, Kumamoto, Japan; Daisuke Sueta, Kumamoto Univ Hosp, Kumamoto, Japan; Hiroki Usuku, Kumamoto Univ Hosp, Kumamoto city, Japan; Seiji Takashio, Kumamoto Univ, Kumamoto, Japan; Koichi Kaikita, Kenichi Tsujita, Kumamoto Univ Hosp, Kumamoto, Japan

12:30 PM

Board # 4079

Right Ventricular Size and Function in Healthy Adults: Geographical Differences From the World Alliance of Societies of Echocardiography (WASE) Normal Values Study

**Tatsuya Miyoshi** , Medstar Health Res Inst, Washington, DC; Karima Addetia, Univ of Chicago, Chicago, IL; Alexandra Blitz, TOMTEC Imaging Systems GmbH, Unterschleissheim, Germany; Roberto M Lang, Univ of Chicago, Chicago, IL; Federico M Asch, MedStar Health Res Inst, Washington, DC; the WASE Investigators

12:30 PM

Board # 4080

Prospective Echocardiographic Study of Low Flow State in a Large Hispanic Population

**Patrick M Kozak** , Min Pu, Wake Forest Baptist Medical Ctr, Winston Salem, NC; Martha L Daviglus, Mayank Mohan Kansal, Univ of Illinois at Chicago, Chicago, IL; Daniela Sotres-Alvarez, Univ of North Carolina, Chapel Hill, NC; Sonia Ponce, Univ of California, San Diego, La Jolla, CA; Swett Katrina, Wake Forest Sch of Med, Winston Salem, NC; David X.M. Zhao, Wake Forest Baptist Medical Ctr, Winston-Salem, NC; Dalane W Kitzman, Wake Forest Baptist Medical Ctr, Winston Salem, NC; Robert Kaplan, Albert Einstein Coll of Med, Bronx, NY; Carlos J Rodriguez, Wake Forest Baptist Medical Ctr, Winston-Salem, NC

12:30 PM

Poster Professor

MARIA DO CARMO Pereira Nunes, Belo Horizonte, Brazil

# Abstract Poster Session

## IM.APS.09 - Echocardiography: General Topics

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4094

Libman-Sacks Endocarditis and Its Associated Cerebrovascular Disease: The Role of Medical Therapy

**Carlos Vazquez** , Richard Snider, Michelle D Ratliff, Wilmer Sibbitt, Clifford Qualls, Carlos A Roldan, Univ of New Mexico Sch of Med, Albuquerque, NM

12:30 PM

Board # 4095

The Role of Echocardiography in Patients With Syncope: A Single-Center Experience

Ali Raza Ghani, Abington Hosp-Jefferson Health, Abington, PA; **Hafez Mohammad Abdullah** , Univ of South Dakota, Sioux Falls, SD; Usman Sarwar, Muhammad Arslan Cheema, Abington Hosp-Jefferson Health, Abington, PA; Waqas Ullah, Abington Hosp-Jefferson Health, Horsham, PA; Shujaul Haq, Asoka Balaratna, Abington Hosp-Jefferson Health, Abington, PA

12:30 PM

Board # 4097

"High Risk" Features of Mitral Annular Calcification on Echocardiography Are Associated With Cerebral Infarction

**Aaron A. H. Smith** , Joseph D. Steffens, Alexander J. Baxa, Jorge Reyes-Castro, Holly Rodin, Mengistu A. Simegn, Richard W. Asinger, Hennepin Healthcare, Minneapolis, MN

12:30 PM

Board # 4099

Echocardiographic Assessment in Patients With Pulmonary Embolism - Prospective Blinded Long Term Follow Up

**Hezzy Shmueli** , Cedars Sinai Medical Ctr, Los Angeles, CA; Arie Steinvil, Tel-Aviv Sourasky Medical Ctr and Sackler Sch of Med, Tel Aviv, Israel; Galit Aviram, Sileman Moaad, Sharon Adam, Simon Biner, Yacov Shacham, Jack Sherez, Ricki Megidish, Yifat Hasin, Ester Elazar, Sevan Letourneau-Shesaf, Gad Keren, Shlomo Berliner, Yan Topilsky, Tel Aviv Sourasky Medical Ctr, Tel Aviv, Israel

12:30 PM

Board # 4100

Global Longitudinal Strain During Dobutamine Stress Echocardiography Can Predict Left Ventricular Remodeling After Anterior Wall Acute Myocardial Infarction

**Toshinari Onishi** , Sakurabashi Watanabe Hosp, Osaka, Japan; Katsuomi Iwakura, Sakurabashi Waturahe Hospi, Osaka, Japan; Atsunori Okamura, Yasushi Koyama, Koichi Inoue, Mutsumi Iwamoto, Satoshi Watanabe, Hiroyuki Nagai, Sakurabashi Watanabe Hosp, Osaka, Japan; Yuko Hirao, Sakurabashi-Watanabe Hosp, Osaka, Japan; Koji Tanaka, Takafumi Oka, Nobuaki Tanaka, Kenshi Fujii, Sakurabashi Watanabe Hosp, Osaka, Japan

12:30 PM

Board # 4101

Non-Diagnostic Dobutamine Stress Echocardiogram by Failing to Achieve Target Heart Rate Predicts Long Term All Cause Mortality

**Divyang Patel** , Anirudh Kumar, Paul Cremer, Serge C Harb, Sneha Vakamudi, Zoran B Popovic, L Leonardo Leonardo Rodriguez, Richard Allen Grimm, Cleveland Clinic, Cleveland, OH; Milind Desai, Cleveland Clinic, Solon, OH; Brian P. Griffin, Samir R kapadia, Venu Menon, Cleveland Clinic, Cleveland, OH; Wael A Jaber, Cleveland Clinic Fndn, Cleveland, OH; Vidyasagar Kalahasti, Cleveland Clinic Fndtion, Cleveland, OH

12:30 PM

Board # 4102

The Spleen From Within: Spleen Size and Appearance by Transesophageal Echocardiography in Patients With Suspected Infective Endocarditis

**Hezzy Shmueli** , Nir Flint, Cedars Sinai Medical Ctr, Los Angeles, CA; Charles Pollick, Cedars-Sinai Heart Inst, Los Angeles, CA; Robert J Siegel, Cedars Sinai Medical Ctr, Los Angeles, CA

12:30 PM

Board # 4103

Abnormal Exercise Physiology in Mitral Annular Calcification

**Benjamin Horn** , Kevin Bryan Lo, Einstein Medical Ctr Philadelphia, Philadelphia, PA; Mary Carolina Rodriguez Ziccardi, Univ of Illinois at Chicago, Chicago, IL; Philip C Wiener, Gregg S Pressman, Einstein Medical Ctr Philadelphia, Philadelphia, PA

12:30 PM

Board # 4104

Impact of Data From a Prior Transthoracic Echocardiogram in the Identification of a Potential Cause for Syncope

**Amrita Mukhopadhyay** , Changyu Shen, Nicholas Kiefer, Ari Kriegel, Karima Ali, Warren J Manning, Beth Israel Deaconess Medical Ctr, Harvard Medical Sch, Boston, MA

12:30 PM

Board # 4105

Libman-Sacks Endocarditis: Who Should Undergo Tee?

**Daniel Levin** , Univ of New Mexico, Albuquerque, NM; Richard Snider, Albuequerque Veterans Affairs Hosp, Albuquerque, NM; Devona Michelle Ratliff, NMVAHCS, Albuquerque, NM; Clifford Qualls, Sibbitt Wilmer Jr, Univ of New Mexico, albuquerque, NM; Carlos A Roldan, Univ of New Mexico, Albuquerque, NM

12:30 PM

Board # 4106

The Impact of Metformin on Myocardial Function in a Community-based Population

**Amera Halabi** , Baker Heart and Diabetes Inst, Melbourne, Australia; Hong (Hilda) Yang, Menzies Res Inst, Hobart, TAS, Australia; Leah Wright, Baker Heart and Diabetes Inst, Melbourne, Australia; Kazuaki Negishi, Univ of Sydney, Penrith, Australia; Thomas H Marwick, Baker Heart and Diabetes Inst, Melbourne, Australia

# Abstract Poster Session

## IM.APS.08 - Echocardiography: Ischemic Disease, Heart Failure and Myocardial Disease

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4081

Therapeutic Ultrasound Improves Myocardial Blood Flow And Reduces Infarct Size in a Canine Model of Coronary Microthromboembolism

**Mrinal Yadava** , Oregon Health and Science Uni, Portland, OR; Dai-Trang Elizabeth Le, VA Portland Health Care System, Portland, OR; Igor Dykan, Matthew Nugent, Azzdine Y Ammi, Oregon Health and Science Uni, Portland, OR; David Giraud, Oregon Health & Science Univ, Portland, OR; Yan Zhao, Jessica Minnier, Oregon Health and Science Uni, Portland, OR; Sanjiv Kaul, OHSU, Portland, OR

12:30 PM

Board # 4082

Coronary Microvascular Dysfunction is Associated With Impaired Myocardial Performance Index in Patients With Reperfused Myocardial Infarction

**Ercole Tagliamonte** , Caterina Montuori, Roberta Astarita, Alberto Forni, Lucia Riegler, Maria Rosaria Tagliamonte, Juri Radmilovic, Andrea d'Amato, Antonello d'Andrea, Hosp "Umberto I", Nocera Inferiore, Italy

12:30 PM

Board # 4083

Ergonovine Provocation Testing With Echocardiographic Monitoring of Left Ventricular Wall Motion for Non-Invasive Diagnosis of Coronary Vasospasm: Safety and Clinical Usefulness

**Sang Yong Om** , Asan Medical Ctr, Seoul, Korea, Republic of; Sang-Yong Yoo, Gangneung Asan Hosp, Gangneung; Goo-Yeong Cho, Seoul Natl Univ Bundang Hosp, Seongnam; Minsoo Kim, Sahmin Lee, Dae-Hee Kim, Asan Medical Ctr, Seoul, Korea, Republic of; Jong-Min Song, Duk-Hyun Kang, Asan Medical Ctr, Seoul; Sang Sig Cheong, Gangneung Asan Hosp, Gangneung, Korea, Republic of; Seong-Wook Park, Seung-jung Park, Jae-kwan Song, Asan Medical Ctr, Seoul, Korea, Republic of

12:30 PM

Board # 4084

Usefulness of Echocardiographic Epicardial Adipose Tissue Thickness for Predicting Coronary Artery Disease Regardless of Body Mass Index

**Yukina Hirata** , Kenya Kusunose, Tokushima Univ Hosp, Tokushima, Japan; Hirotsugu Yamada, Tokushima Univ Graduate Sch of Biomedical Sciences, Tokushima, Japan; Yuta Torii, Tokushima Univ Hospl, Tokushima, Japan; Susumu Nishio, Nao Yamada, Koji Yamaguchi, Takeshi Soeki, Tetsuzo Wakatsuki, Masataka Sata, Tokushima Univ Hosp, Tokushima, Japan

12:30 PM

Board # 4085

Image-Cad: A Randomized Trial to Compare Non-Invasive Imaging Strategies in Patients With Suspected Coronary Artery Disease

Victoria Sarban, Jonathan Choy, Richard Coulden, Univ of Alberta, Edmonton, AB, Canada; Alison Deighton, Broadstreet Health Economics & Outcomes Res, Vancouver, BC, Canada; Imran Hassan, Univ of Alberta, EPICORE Ctr, Edmonton, AB, Canada; Karissa Johnston, Broadstreet Health Economics & Outcomes Res, Vancouver, BC, Canada; Lucille Lalonde, Michael Sean McMurtry, Eila Mirhadi, Univ of Alberta, Edmonton, AB, Canada; Jissy Thomas, Mazankowski Alberta Heart Inst, Edmonton, AB, Canada; Ross Tsuyuki, Univ of Alberta, EPICORE Ctr, Edmonton, AB, Canada; Robert Welsh, **Harald Becher** , Univ of Alberta, Edmonton, AB, Canada

12:30 PM

Board # 4086

A Deep Neural Network to Estimate Coronary Flow Reserve From Echocardiography

**Andreas A Werdich** , Shinichi Goto, Alexander J Blood, One Brave Idea/Brigham and Women's Hosp, Boston, MA; Marcelo F DiCarli, Brigham and Women's Hosp, Boston, MA; Calum A MacRae, Rahul C Deo, One Brave Idea/Brigham and Women's Hosp, Boston, MA

12:30 PM

Board # 4087

Impact of Left Ventricular Suction During Exercise on Clinical Outcomes in Patients With Heart Failure

**Shingo Tsujinaga** , Hiroyuki Iwano, Suguru Ishizaka, Yasuyuki Chiba, Miwa Sarashina, Hokkaido Univ, Sapporo, Japan; Michito Murayama, Masahiro Nakabachi, Shinobu Yokoyama, Hisao Nishino, Hokkaido Univ Hosp, Sapporo, Japan; Kazunori Okada, Sanae Kaga, Takuma Sato, Toshihisa Anzai, Hokkaido Univ, Sapporo, Japan

12:30 PM

Board # 4088

Dynamic Assessment of Total Cardiac Output and Ventilatory Efficiency During Echocardiographic Exercise Testing Combined With Respiratory Gas Analysis in Patients Supported With Heart Mate III Left Ventricular Assist Device

**Maurizio Losito** , IRCCS Policlinico San Donato, Milano, Italy; Monica Barki, Cardiology Univ Dept, Segrate Milan, Italy; Vincenzo Tarzia, Azienda Ospedaliera di Padova Cardiac Surgery, Padova, Italy; Gino Gerosa, Univ of Padova, Padova, Italy; Tiziana Setzu, Riabilitazione Cardiologica Lonigo, Lonigo, Italy; Chiara Tessari, Azienda Ospedaliera di Padova, Padova, Italy; Marco Guazzi, IRCCS Policlinico San Donato, Milano, Italy; Mauro Boschello, Riabilitazione Cardiologica Lonigo, Lonigo, Italy

12:30 PM

Board # 4090

Associations Between HIV Serostatus and Cardiac Structure and Function Evaluated by Two-Dimensional Echocardiography in the Multicenter AIDS Cohort Study (MACS)

**Henrique Doria De Vasconcellos** , Wendy S Post, Johns Hopkins Univ, Baltimore, MD; Ann M Ervin, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Todd T Brown, Johns Hopkins Univ, Baltimore, MD; Matthew Budoff, Los Angeles Biomedical Res Inst at Harbor, Torrance, CA; Carlos Malvestutto, Ohio State Univ Medical Ctr, Columbus, OH; Sean Altekruse, Natl Insts of Health, Bethesda, MD; Jared W Magnani, Univ of Pittsburgh, Pittsburgh, PA; Matthew Feinstein, Northwestern Univ Feinberg Sch of Med, Chicago, IL; Joao A C Lima, Katherine C Wu, Johns Hopkins Univ, Baltimore, MD

12:30 PM

Board # 4091

Cardiac Testing For Coronary Artery Disease In Potential Liver Transplant Recipients: A Systematic Review Of Test Accuracy Studies Comparing Dobutamine Stress Echocardiogram And Myocardial Perfusion Imaging

**Jyothi Margapuri** , Sandeep Jubbal, Univ of Massachusetts Medical Sch, Worcester, MA; Nidhi Madan, Rush Univ Medical Ctr, Chicago, IL; Adarsh Katamreddy, Jacobi Medical Ctr-AECOM, Bronx, NY; Nidhish Tiwari, Jacobi Medical Ctr, Albert Einstein Coll of Med, Bronx, NY

12:30 PM

Board # 4092

Left Atrial Size as a Predictor of Sudden Cardiac Death

**Summit Pandat** , Takafumi Nagaura, Cedars Sinai Medical Ctr, W Hollywood, CA; Kyndaron Reinier, Cedars Sinai Medical Ctr, Los Angeles, CA; Audrey Uy-Evanado, Cedars-Sinai Medical Ctr, Los Angeles, CA; Eric Stecker, Knight Cardiovascular Ctr, Portland, OR; Greg Nichols, Ctr for Health Res, Kaiser Permanente, Portland, OR; Jonathan Jui, OHSU, Wilsonville, OR; Takahiro Shiota, Cedars Sinai Heart Inst, Los Angeles, CA; Sumeet S Chugh, Cedars Sinai Medical Ctr, Los Angeles, CA

12:30 PM

Board # 4093

Epidemiology of Undiagnosed Coronary Artery Disease in Acute Decompensated Heart Failure Patients

Wafic Itani, Hiren Patel, **Evan Joye** , Mikhail Torosoff, Albany Medical Ctr, Albany, NY

# Abstract Poster Session

## EA.APS.09 - Electrophysiology and Arrhythmias I

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2010

Biomechanical and Electrophysiological Phenotypic Correction of Congenital Long Qt Syndrome Using Crispr Interference in a 3D Cardiac Microtissue Model

**Chenyu Huang** , Johns Hopkins Univ, Baltimore, MD; Chin Siang Ong, Jingnan Han, Joseph Boktor, Roald Teuben, Ijala Wilson, Deborah DiSilvestre, Johns Hopkins Hosp, Baltimore, MD; Leslie Tung, Johns Hopkins Univ, Baltimore, MD; Narutoshi Hibino, Johns Hopkins Hosp, Baltimore, MD; Daniel Reich, Johns Hopkins Univ, Baltimore, MD; Gordon F Tomaselli, Albert Einstein Coll of Med, Bronx, NY

12:30 PM

Board # 2011

Atrial Fibrillation Profoundly Remodels Mitochondrial Biochemistry, Function and Structural Morphology

**XiaoYan Qi** , Jiening Xiao, Montreal Heart Inst, Univ de Montréal, Montreal, QC, Canada; Jean-Baptiste Guichard, CHU de Saint-Etienne, Saint-priest-en-jarez, France; Stanley Nattel, Montreal Heart Inst, Univ de Montréal, Montreal, QC, Canada

12:30 PM

Board # 2012

Tbx18 Orchestrates Cytostructural Transdifferentiation of Cardiomyocytes to Pacemaker Cells by Recruiting the Epithelial-Mesenchymal Transition Program

**D Brian Foster** , Johns Hopkins Sch of Med, Baltimore, MD; Jin-mo Gu, Emory Univ Sch of Med, Atlanta, GA; Elizabeth H. Kim, Cedars Sinai Medical Ctr, Los Angeles, CA; Hee Cheol Cho, Emory Univ Sch of Med, Atlanta, GA

12:30 PM

Board # 2013

**Altered Beta-Adrenergic Responsiveness of Cardiac L-Type Ca** 2+ **Channels in a Mouse Model of Human Calmodulinopathy**

**Shuai Guo** , Indiana Univ, Indianapolis, IN; WenChin Tsai, Buddhist Tzu Chi General Hosp, Hualien, Taiwan; Peng-Sheng Chen, Krannert Inst Of Cardiolo, Indianapolis, IN; Michael Rubart, Indiana Univ, Indianapolis, IN

12:30 PM

Board # 2014

Development of Preclinical Canine Models to Facilitate Drug-Discovery for Atrial Fibrillation

**Till Freudenberger** , Bayer AG, Pharmaceuticals, R and D, Wuppertal, Germany; William J. Hucker, Massachusetts General Hosp, Boston, MA; Beate Kranz, Waldemar Lehmann, Katja Schaefer, Klaus Muenter, Bayer AG, Pharmaceuticals, R and D, Wuppertal, Germany; Kichang Lee, Patrick T Ellinor, Massachusetts General Hosp, Boston, MA; Joerg Hueser, Bayer AG, Pharmaceuticals, R and D, Wuppertal, Germany

12:30 PM

Board # 2016

Activation of AMPK-Activated Protein Kinases Prevents Atrial Fibrillation

**Cevher Ozcan** , Zhenping Li, Bijoy Chellan, Univ of Chicago, Chicago, IL

12:30 PM

Board # 2017

**Heart Failure Induced Alteration of MicroRNAs Associated With Down-Regulation of Neuronal Sodium Channel Na** V **1.6 May Cause Human Sinoatrial Node Dysfunction**

**Ning Li** , Anuradha Kalyanasundaram, Esthela J Artiga, Brian J Hansen, The Ohio State Univ, Columbus, OH; Amy Feather, Univ of Manchester, Manchester, United Kingdom; Galina Rozenberg, Katelynn M Helfrich, Bryan Whitson, Nahush A Mokadam, Paul ML. Janssen, Peter J Mohler, Federica Accornero, The Ohio State Univ, Columbus, OH; Halina Dobrzynski, Univ of Manchester, Manchester, United Kingdom; Vadim V Fedorov, The Ohio State Univ, Columbus, OH

12:30 PM

Board # 2018

Decreased Cardiac Pacemaking and Attenuated β-adrenergic Response in Tric-a Knockout Mice

**Yuichi Toyama** , Manabu Yonekura, Hirofumi Tomita, Hirosaki Univ Graduate Sch of Med, Aomori, Japan; Takayoshi Ohba, Akita Univ Graduate Sch of Med, Akita, Japan; Agnieszka M Murakami, Manabu Murakami, Hirosaki Univ Graduate Sch of Med, Aomori, Japan

12:30 PM

Board # 2019

Cardiomyocyte-Specific STIM1 Depletion in the Adult Heart Promotes Arrhythmogenic Discordant Alternans

**Marine Cacheux** , Cardiovascular Res Ctr, Icahn Sch of Med at Mount Sinai, New York, NY; Zeki Ilkan, The Mount Sinai Hosp, New York, NY; Jean-Sebastien Hulot, Cardiovascular Res Ctr, Icahn Sch of Med at Mount Sinai, New York, NY; Fadi G Akar, Mount Sinai Sch of Med, New York, NY

12:30 PM

Poster Professor

Fadi G Akar, New York, NY

# Abstract Poster Session

## EA.APS.11 - Electrophysiology and Arrhythmias II

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2033

NFTAc1 **is a Novel Atrial Fibrillation Susceptibility Gene**

**Natalia S Torres** , Meganne Ferrel, Chuanchau Jerry Jou, Cammon B Arrington, Neil E Bowles, Derek Lundahl, Alexandra Acuna, Karishma Shah, Scott Cho, Christopher Kauffman, Mark Yandell, Martin Tristani-Firouzi, Univ of Utah, Salt Lake City, UT

12:30 PM

Board # 2034

Novel TMEM168 Gene Mutation in Brugada Syndrome Impairs Sodium Channel Function via the Nav1.5 Degradation

**Hisakazu Ogita** , Dimitar P. Zankov, Akio Shimzu, Shiga Univ of Medical Science, Otsu, Japan

12:30 PM

Board # 2035

**KCNQ1 Channel Dysfunction in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Carrying a** CALM2 **-N98S Mutation Associated With Long QT Syndrome**

**Yuta Yamamoto** , Takeru M Makiyama, Yimin Wuriyanghai, Kyoto Univ, Kyoto, Japan; Hirohiko Kohjitani, Kyoto Univ Hosp, Kyoto, Japan; Sayako Hirose, Kyoto Univ, Sakyo-ku, Kyoto, Japan; Jingshan Gao, Asami Kashiwa, Huang Hai, Takanori Aizawa, Tomohiko Imamura, Kyoto Univ, Kyoto, Japan; Taisuke Ishikawa, Seiko Ohno, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Kazuhisa Chonabayashi, Kyoto Univ, Kyoto, Japan; Hideki Motomura, Nagasaki Univ Hosp, Nagasaki, Japan; Yoshinori Yoshida, Kyoto Univ, Kyoto, Japan; Minoru Horie, Shiga Univ of Medical Science, Ohtsu, Japan; Naomasa Makita, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Takeshi Kimura, Kyoto Univeristy, Kyoto, Japan

12:30 PM

Board # 2036

Diet and Atrial Myocardial Properties

Nadine Suffee, INSERM UMRS1166, Paris, France; Elodie Baptista, ICAN Inst, Paris, France; Jerome Piquereau, UMRS 1180, Chatenay Malabry, France; Maharajah Ponnaiah, Farid Ichou, Nicolas Doisne, Wilfried LeGoff, ICAN Inst, Paris, France; Mathias Mericskay, INSERM -Univ Paris Saclay, Châtenay-Malabry, France; **Stephane Hatem** , ICAN Inst, Paris, France

12:30 PM

Board # 2037

HDAC6 Activation Plays Important Roles in the Development of Atrial Fibrillation in Transgenic Mice

**Sawa Yohei** , Iwate Medical Univ Sch of Med, Morioka, Iwate, Japan; Maki Saito, Iwate Medical Univ Sch of Phamaceutical Sciences, Shiwa-gun Iwate, Japan; Nanae Ishida, Iwate Medical Univ Sch of Pharmaceutical Science, Shiwa-gun, Iwate, Japan; Miho Ibi, Iwate Medical Univ Sch of Density, Shiwa-gun, Iwate, Japan; Naoko Matsushita, Iwate Medical Univ Sch of Med, Morioka, iwate, Japan; Yoshihiro Morino, Iwate Medical Univ, Marioka, Japan; Eiichi Taira, Iwate Medical Univ Sch of Med, Shiwa-gun, Iwate, Japan; Masamichi Hirose, Iwate Medical Univ Sch of Pharmaceutical Sciences, Shiwa-gun Iwate, Japan

12:30 PM

Board # 2038

Electrical Remodeling of Cardiac Parasympathetic Postganglionic Neurons and Ventricular Arrhythmogenesis in Diabetes

Dongze Zhang, UNMC, Omaha, NE; Huiyin Tu, Wenfeng Hu, Michael C Wadman, **Yulong Li** , Univ of Nebraska Medical Ctr, Omaha, NE

12:30 PM

Board # 2039

Preferential Release of Nerve Growth Factor by the Left Atrial Appendage - A New Mechanism Underlying Autonomic Nerve Remodeling in Persistent Atrial Fibrillation?

**Anna Pfenniger** , Shin Yoo, Wenwei Zhang, Amy Burrell, David A Johnson, Georg Gussak, Lisa Wren, Mehul Gilani, Bradley P Knight, Rod S Passman, Rishi Arora, Northwestern Univ Feinberg Medical Sch, Chicago, IL

12:30 PM

Board # 2040

**Mitochondrial Connexin43 and Mitochondrial K** ATP **Channels Affect the Occurrence of Arrhythmias**

**Masami Nishiyama** , Natsuki Morita, Yuka Someya, Yui Takahashi, Ayana Matsumoto, Chiyohiko Shindoh, Haruka Sato, Masahito Miura, Tohoku Univ Grad Sch of Med, Sendai, Japan

12:30 PM

Board # 2041

Dose Dependent Responses to Subcutaneous Nerve Stimulation in Ambulatory Dogs With Persistent Atrial Fibrillation

**Takashi Kusayama** , Indiana Univ Sch of Med, Indianapolis, IN; Juyi Wan, The Affiliated Hosp of Southwest Medical Univ, Luzhou, China; Yuan Yuan, Xinhua Hosp, Sch of Med, Shanghai Jiao Tong Univ, Shanghai, China; Xiao Liu, Indiana Univ Sch of Med, Indianapolis, IN; Changyu Shen, 5The Richard and Susan Smith Ctr for Outcomes Res in Cardiology, Beth Israel Deaconess Medical Ctr, Harvard Medical Sch, Boston, MA; Michael C Fishbein, UCLA Hlth Sci, Los Angeles, CA; Thomas H. Everett, Peng-Sheng Chen, Indiana Univ Sch of Med, Indianapolis, IN

12:30 PM

Board # 2042

Suppression of Electrical Conduction Across the Right Ventricular Insertion Reduces the Defibrillation Threshold Voltage

Han Yu, **Hanyu Zhang** , Gregory P Walcott, Jack M Rogers, Univ of Alabama at Birmingham, Birmingham, AL

12:30 PM

Poster Professor

Isabelle Deschenes, Columbus, OH

12:30 PM

Board # 2043

Blocking an Ion Channel With a Bioengineered Peptibody

**Bojjibabu Chidipi** , Obada Abou-Assali, Michelle Reiser, Justin Shane Hooper, Thomas Taylor-Clark, Michael N Teng, Sami F Noujaim, Univ of South Florida, Tampa, FL

12:30 PM

Board # 2044

A Novel CALM3 Variant Associated With a Mild LQTS Phenotype

**Koichi KATO** , Sorbonne Univ, Inserm, Inst of Cardiometabolism and Nutrition (ICAN), Paris, France; Holly M Isbell, Univ of Iowa, Carver Coll of Med, Iowa, IA; Véronique Fressart, AP-HP, Pitié-Salpêtrière Hosp, Paris, France; Isabelle Denjoy, AP-HP, Bichat Hosp, Ctr de Référence des Maladies Cardiaques Héréditaires, Paris, France; Amal Debbiche, Sorbonne Univ, Inserm, Inst of Cardiometabolism and Nutrition (ICAN), Paris, France; Hideki Itoh, Shiga Univ of Medical Science, Otsu, Japan; Jacques Poinsot, Ctr Univire de Tours, Tours, France; Alfred L George Jr., Northwestern Univ Feinberg Sch of Med, Chicago, IL; Alain Coulombe, Sorbonne Univ, Inserm, Inst of Cardiometabolism and Nutrition (ICAN), Paris, France; Madeline A Shea, Univ of Iowa, Carver Coll of Med, Iowa, IA; Pascale Guicheney, Sorbonne Univ,Inserm,Inst of Cardiometabolism and Nutrition (ICAN), Paris, France

12:30 PM

Board # 2045

Synonymous Modification of hERG Regulates Translation Rate and RNA Stability

Jiajia Yang, Univeristy of South Florida, Tampa, FL; Marika L Osterbur, Albert Einstein Coll of Med, Bronx, NY; Thomas V McDonald, Univ of South Florida, Tampa, FL; **Alexander Bertalovitz** , Univeristy of South Florida, Tampa, FL

# Abstract Poster Session

## AT.APS.10 - Endothelial Dysfunction and Atherosclerosis

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 1000

Endothelial Cell RNAseq in Hypercholesterolemic Zebrafish Reveals Early Dynamic Changes in Neuromast-Enriched Genes

**Wei Dai** , Brigham and Women's Hosp, Boston, MA; Aaron P Kithcart, Brigham and Womens Hosp, Boston, MA; Nicholas Rainville, Brigham and Women's Hosp, Boston, MA; Rahul C Deo, Brigham and Women's Hosp, San Francisco, CA; Manu Beerens, BWH - Harvard Medical Sch, Boston, MA; Calum MacRae, Brigham and Women's Hosp, Boston, MA

12:30 PM

Board # 1001

Abnormal Endothelial Gene Expression in Humans is Associated With Early Coronary Atherosclerosis

Robert P Hebbel, Liming Milbauer, Peng Wei, Univ of Minnesota, Minneapolis, MN; **Michel Corban** , Mayo Clinic Coll of Med and Science, Rochester, MN; Anna Solovey, James Kiley, Univ of Minnesota, Minneapolis, MN; Lilach O Lerman, Mayo Clinic, Rochester, MN; Wei Pan, Univ of Minnesota, Minneapolis, MN; Amir Lerman, Mayo Clinic, Rochester, MN

12:30 PM

Board # 1002

Endothelial Function in Healthy Adults is Unaffected by Elevated Serum Trimethylamine N-oxide Levels Following One Month of Dietary Choline Supplementation

**Scott T Chiesa** , UCL, London, United Kingdom; Marietta Charakida, King's Coll London, London, United Kingdom; Alicja Rapala, Devina J Bhowruth, UCL, London, United Kingdom; Charles Turner, Neil Dalton, St. Thomas Hosp, London, United Kingdom; John E Deanfield, UCL, London, United Kingdom

12:30 PM

Board # 1003

S1p2 Receptor Antagonist Attenuates Endothelial Dysfunction and Inhibits Atherogenesis in Apolipoprotein-e-deficient Mice

**Byambasuren Ganbaatar** , Inst of biomedical science, Tokushima, Japan; Daiju Fukuda, Inst of Biomedical Sciences, Tokushima Univesity, Tokushima, Japan; Shusuke Yagi, Univ of Rochester, Tokushima, Japan; Kenya Kusunose, Hirotsugu Yamada, Inst of biomedical science, Tokushima Univ, Tokushima, Japan; Takeshi Soeki, Inst of Biomedical Sciences, Tokushima Univ, Tokushima, Japan; Masataka Sata, Tokushima Univ Graduate Sch, Tokushima, Japan

12:30 PM

Board # 1004

Cu Transporter ATP7A Protects Against Atherosclerosis by Limiting Endothelial-to-mesenchymal Transition Through Regulating Cu, ROS and Glycolysis

**Dipankar Ash** , Med. Coll. of Georgia at Augusta Univ, Augusta, GA; Seock-Won Youn, Univ of Illinois at Chicago, Chicago, IL; Sudhahar Varadarajan, Archita Das, Tohru Fukai, Masuko Ushio-Fukai, Med. Coll. of Georgia at Augusta Univ, Augusta, GA

12:30 PM

Board # 1005

Long Non-Coding RNA-Mediated Chromatin Remodeling in Diabetic Endothelial Dysfunction

Riccardo Calandrelli, Univ of California San Diego, La Jolla, CA; Yingjun Luo, Kiran Sriram, City of Hope, Duarte, CA; Sheng Zhong, Univ of California San Diego, La Jolla, CA; **Zhen Chen** , City of Hope, Duarte, CA

12:30 PM

Board # 1006

Nonsteroidal Anti-inflammatory Drugs Produce Dose-dependent Inhibition of Endothelial Cell Migration

**Kelley Chen** , Linda M. Graham, Cleveland Clinic, Cleveland, OH

12:30 PM

Board # 1007

Patient-specific Analysis Predicts Preferential Accumulation of VCAM-1 Targeted Nanoparticles Near Atherosclerotic Plaque

**Shaolie S Hossain** , Texas Heart Inst, Houston, TX; Daniel Chavarria, Aaron Baker, Thomas JR Hughes, The Univ of Texas at Austin, Austin, TX

12:30 PM

Board # 1008

Nicotinamide Nucleotide Transhydrogenase (NNT) Regulates Oxldl Induced Endothelial Activation

**Shashanka Rao** , Sibile Pardue, Xinggui Shen, David M Krzywanski, LSU Health Sciences Ctr, Shreveport, LA

12:30 PM

Board # 1009

Endothelial Foxp1 Suppresses Neointimal Formation Through MMP-9 Signal Pathway

**Tao Zhuang** , Xiaoli Chen, Jie Liu, Jingjiang Pi, Yashu Kuang, Yanfang Wang, Lin Zhang, Yuzhen Zhang, Shanghai East Hosp, Tongji Univ Sch of Med, Shanghai, China

12:30 PM

Board # 1010

Statins Ameliorates Chronic Stress-Related Vascular Aging and Atherosclerotic Plaque Growth in ApoE-Deficient Mice Fed High Fat-Diet

**Yanna Lei** , Limei Piao, Yanbian Univ Hosp, Yanji, China; Masafumi Kuzuya, Nagoya Univ Graduate Sch of Med, Nagoya, China; Xian Wu Cheng, Yanbian Univ Hosp, Yanji, China

12:30 PM

Board # 1012

Longitudinal Association Between Early/Late Systolic Cardiac Load and the Impairment of Left Ventricular Systolic Function in Its Early Stage

**Hiroki Nakano** , Hirofumi Tomiyama, Taishiro Chikamori, Akira Yamashina, Tokyo Medical Univ, Tokyo, Japan

# Abstract Poster Session

## PR.APS.01 - Exercise and Athletics - Screening and Outcomes

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 3212

Prediction of an Adverse Cardiovascular Response to Physical Exercise From Resting Echocardiography Imaging in Young Adults With Suboptimal Blood Pressure

**Maryam Alsharqi** , Odaro J Huckstep, Wilby Williamson, Univ of Oxford, Oxford, United Kingdom; Afifah Mohamed, Univ of Oxford,, Oxford, United Kingdom; Cheryl Tan, Winok Lapidaire, Fernando Telles, Univ of Oxford, Oxford, United Kingdom; Linda Arnold, CCRF, Oxford, United Kingdom; Cristiana Monteiro, Univ of Oxford, Headington, United Kingdom; Helen Dawes, Oxford Brookes Univ, oxford, United Kingdom; Charlie Foster, Univ of Bristol, Bristol, United Kingdom; Adam J Lewandowski, Paul Leeson, Univ of Oxford, Oxford, United Kingdom

12:30 PM

Board # 3213

Accuracy of Methods for Stroke Volume Measures by O2-pulse During Gas Exchange Analysis and Clinical Implications

Martina Evangelista, IRCCS Policlinico San Donato, Univ of Milan, Milano, Italy; Sara Boveri, IRCCS Policlinico San Donato, Milano, Italy; Eleonora Alfonzetti, IRCCS Policlinico San Donato, Univ of Milan, Milano, Italy; Francesco Bandera, **Marco Guazzi** , IRCCS Policlinico San Donato, Milano, Italy

12:30 PM

Board # 3214

Systematic Screening for Cardiovascular Disease in Young Sports Participants

**Rasha Aurshiya** , Kunal Bhagatwala, Archana Sinha, Jasmine Singh, Sudip Nanda, Jamshid Shirani, St Luke's Univ Hosp Bethlehem, Bethlehem, PA

12:30 PM

Board # 3215

Diagnostic Performance of 37 Electrocardiographic Criteria for Detecting Left Ventricular Hypertrophy or a Concentric Cardiac Phenotype in Athletes

**Kristofer Hedman** , Kegan J Moneghetti, David Hsu, Jeffrey Christle, Alessandro Patti, Euan A Ashley, Stanford Univ, Stanford, CA; Francois Haddad, Stanford Univ, Stanford University, CA; Victor Froelicher, Stanford Univ, Stanford, CA

12:30 PM

Board # 3216

A Method to Detect Individual Changes in Exercise Tolerance

**Hirotaka Nishijima** , Kazuo Kondo, Masayuki Sakurai, Hokko Memrial Hosp, Sapporo, Japan

12:30 PM

Board # 3217

Racial and Ethnic Trends in Athlete ECG Interpretation Utilizing International ECG Criteria

**Max Weiss** , Thomas Jefferson Univ Hosp, Philadelphia, PA; Prashant Rao, Thomas Jefferson Univ, Philadelphia, PA; Chris Koilor, Thomas Jefferson Univ Hosp, Philadelphia, PA; Renee Langstaff, Arcadia Univ, Glenside, PA; David Shipon, Thomas Jefferson Univ Hosp, Philadelphia, PA

12:30 PM

Board # 3219

Routes and Barriers to Return to Play in Athletes With Cardiac Disease

**Kayle S. Shapero** , Chad Gier, Yale New Haven Hosp, New Haven, CT; Michael John Ackerman, Mayo Clinic, Rochester, MN; Erica S Spatz, Yale Univ Sch Med, New Haven, CT; Meagan M Wasfy, Aaron L Baggish, Massachusetts General Hosp, Boston, MA; Rachel J Lampert, Yale Sch of Med, New Haven, CT

12:30 PM

Board # 3220

A Community Health Worker-Led Health Education and Coaching Intervention Improves Hypertension Control Among South Asian Primary Care Patients in New York City

**Jennifer Zanowiak** , Nadia Islam, Sadia Mohaimin, Priscilla Lopez, NYU Sch of Med, New York, NY; Anna Divney, CUNY Graduate Sch of Public Health and Health Policy, New York, NY; Laura Wyatt, NYU Sch of Med, New York, NY; NYU Community Health Workers; Lorna Thorpe, Chau Trinh-Shevrin, NYU Sch of Med, New York, NY

12:30 PM

Board # 3221

Variability In Pre-Participation Physical Evaluation (PPE) Cardiovascular Screening of High School Athletes on Long Island-Assessing the Impact of 2014 AHA/ACC Guidelines Update

**Siri Kommareddy** , Stony Brook Children's Hosp, Stony Brook, NY; Caitlin Heyden, Laurie E. Panesar 11794, Stuart Holzer 11794, Stony Brook Children's Hosp, Stony Brook, NY; Marybeth Heyden, Catherine Messina 11794, Stony Brook Children's Hosp, Stony Brook, NY

# Abstract Poster Session

## IN.APS.07 - Fairy Tales from the Cath Lab

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4137

Impact of Calcified Plaque on Vascular Remodeling After Bioresorbable Vascular Scaffold Implantation; Insights From the ABSORB III and ABSORB Japan Trials

**Shinji Imura** , Stanford Univ, stanford, CA; Takeshi Nishi, Stanford Univ, Stanford, CA; Kozo Okada, Yokohama City Univ Med Ctr, Yokohama, Japan; Hideki Kitahara, Chiba Univ Hosp, Chiba, Japan; Ryo Kameda, Kitasato, Sagamihara, Japan; Masayasu Ikutomi, Univ Tokyo Graduate Sch, Tokyo, Japan; Brooke Hollak, Stanford Univ, stanford, CA; Paul G Yock, Stanford Univ, Stanford, CA; Jeffrey J Popma, Beth Israel Deaconess Medical Ctr, Boston, MA; Hajime Kusano, Wai-Fung Cheong, Abbott, Santa Clara, CA; Krishna Sudhir, Abbott Vascular, Santa Clara, CA; Peter Fitzgerald, Stanford Univ Sch Med, Stanford, CA; Stephen G Ellis, Cleveland Clinic Fndn, Cleveland, OH; Dean Kereiakes, The Christ Hosp Heart and Vascular Ctr/The Lindner Res Ctr, Cincinnati, OH; Gregg W Stone, Columbia Univ Medical Ctr, New York, NY; Yasuhiro Honda, Stanford Univ, Stanford, CA; Takeshi Kimura, Kyoto Univeristy, Kyoto, Japan

12:30 PM

Board # 4138

The Role of Routine Angiographic Follow-up Afte Percutaneous Coronary Intervention -a Meta Analysis Including 14199 Patients

**Jin Xu** , Yu Peng, Zheng Zhang, Yibo Wang, The Frist Hosptial of Lanzhou Univ, Lanzhou, China

12:30 PM

Board # 4139

Percutaneous Coronary Intervention Provides a Unique Benefit to Inpatient Mortality for Cancer Patients With Coronary Artery Disease

**Sean M Lawless** , Dominique Monlezun, McGovern Medical Sch at The Univ of Texas Health Science Ctr at Houston, Houston, TX; Nicolas Palaskas, Juan Lopez-Mattei, Peter Kim, The Univ of Texas MD Anderson Cancer Ctr, Houston, TX; Konstantinos Marmagkiolis, Pepin Heart Inst, Florida Hosp Tampa, Tampa, FL; Cezar Iliescu, The Univ of Texas MD Anderson Cancer Ctr, Houston, TX

12:30 PM

Board # 4140

Impact of Peri-scaffold Plaque Burden on Long-term Arterial Response and Target Lesion Failure Following Absorb Bioresorbable Scaffold Implantation

**Takeshi Nishi** , Stanford Univ, Stanford, CA; Kozo Okada, Yokohama City Univ Med Ctr, Yokohama, Japan; Hideki Kitahara, Chiba Univ, Chiba, Japan; Ryo Kameda, Kitasato, Sagamihara, Japan; Masayasu Ikutomi, Univ Tokyo Graduate Sch, Tokyo, Japan; Brooke Hollak, Paul G Yock, Stanford Univ, Stanford, CA; Jeffrey J Popma, Beth Israel Deaconess Medical Ctr, Boston, MA; Hajime Kusano, Wai-Fung Cheong, Krishna Sudhir, Abbott Vascular, Santa Clara, CA; Peter Fitzgerald, Stanford Univ Medical Ctr, Stanford, CA; Stephen G Ellis, Cleveland Clinic Fndn, Cleveland, OH; Dean J Kereiakes, Ohio Heart Health Ctr, Cincinnati, OH; Gregg W Stone, Columbia Univ Medical Ctr, New York, NY; Yasuhiro Honda, Stanford Univ, Stanford, CA; Takeshi Kimura, Kyoto Univeristy, Kyoto, Japan

12:30 PM

Board # 4141

Recalibration of the NCDR CathPCI Bleeding Risk Score in a Contemporary ST-Segment Elevation Myocardial Infarction Cohort Receiving Primary Percutaneous Coronary Intervention

**Michael J Thibert** , Christopher Fordyce, Joel Singer, John A Cairns, Wendy Tocher, Terry Lee, Michelle Perry Arnesen, Graham C Wong, Univ of British Columbia, Vancouver, BC, Canada

12:30 PM

Board # 4142

Defining the Optimal Threshold for Maintaining Transfemoral PCI Proficiency in the Era of Increasing Transradial PCI: Insights From BMC2

**David Kopin** , Milan Seth, Univ of Michigan, Ann Arbor, MI; Devraj Sukul, Univ of Michigan Health Syste, Ann Arbor, MI; Hitinder S Gurm, Univ of Michigan, Ann Arbor, MI

12:30 PM

Board # 4143

Mobilization of Endothelial Progenitor Cells and Vessel Healing After Implantation of Abluminal Biodegradable Polymer Coating Everolimus-Eluting Stent

**Masashi Sakuma** , Setsu Nishino, Tomoaki Kanaya, Shigeru Toyoda, Shichiro Abe, Teruo Inoue, Dokkyo Medical Univ, Mibu, Japan

12:30 PM

Board # 4144

Percutaneous Coronary Interventions of Chronic Total Occlusion-the Michigan Experience: Insights From the Blue Cross Blue Shield of Michigan Cardiovascular Consortium

**Rami Kassem Zein** , St. John Hosp and Medical Ctr, Detroit, MI; Milan Seth, Univ of Michigan, Ann Arbor, MI; Hussein Othman, St. John Hosp and Medical Ctr, Detroit, MI; Howard S Rosman, St. John Medical Ctr, Detroit, MI; Khaldoon Alaswad, Henry Ford Hosp, Detroit, MI; Hiroshi Yamasaki, St. John Hosp and Medical Ctr, Roseville, MI; Thomas LaLonde, Eastlake CV Associates, St. Clair Shores, MI; Dan Menees, Univ of Michigan Medical Ctr, Ann Arbor, MI; Rajendra H Mehta, Duke Clinical Res Inst, Durham, NC; Hitinder S Gurm, Univ of Michigan, Ann Arbor, MI; Edouard Daher, St. John Hosp and Medical Ctr, Detroit, MI

12:30 PM

Board # 4145

Contemporary In-hospital Outcomes of Chronic Total Occlusion Interventions: Update From the Progress-CTO (Prospective Global Registry for the Study of Chronic Total Occlusion Intervention) International Registry

**Iosif Xenogiannis** , Minneapolis Heart Inst and Minneapolis Heart Inst Fndn, Minneapolis, MN; Dimitrios Karmpaliotis, Columbia Univ, New York, NY; Khaldoon Alaswad, Henry Ford Cardiovascular Div, Birmingham, MI; Oleg Krestyaninov, Dmitri Khelimski, Meshalkin Novosibrisk Res Inst, Novosirbirsk, Russian Federation; James Choi, Baylor Heart and Vascular Hosp, Dallas, TX; Jaikirshan J Khatri, Cleveland Clinic, Cleveland, OH; Farouc A Jaffer, Massachusetts General Hosp, Boston, MA; Mitul P Patel, UC San Diego Health System, San Diego, CA; Ehtisham Mahmud, Sulpizio Cardiovascular Ctr, La Jolla, CA; Anthony Doing, Philip Dattilo, Medical Ctr of the Rockies, Loveland, CO; David E Kandzari, Piedmont Heart Inst, Atlanta, GA; Michalis Koutouzis, Ioannis Tsiafoutis, Red Cross Hosp of Athens, Athens, Greece; Barry F Uretsky, Central Arkansas VA system, Fort Smith, AR; Catalin Toma, UPMC, Pittsburgh, PA; Robert W Yeh, Beth Israel Deaconess Med Ctr, Boston, MA; Hector Tamez, Beth Israel Deaconess Medical Ctr, Boston, MA; Michael Wyman, Torrance Memorial Medical Ctr, Torrance, CA; Brian K. Jefferson, Taral Patel, Tristar Centennial Medical Ctr, Nasville, TN; Wissam Jaber, Emory Univ, Atlanta, GA; Habib Samady, Emory Univ Hosp Midtown, Atlanta, GA; Abdul Sheikh, Wellstar Health System, Marietta, GA; Bilal Malik, Maimonides Medical Ctr, Brooklyn, NY; Srini Potluri, The Heart Hosp Baylor Plano, Plano, TX; Basem Elbarouni, Michael Love, St. Boniface General Hosp, Winnipeg, MB; Shah Alpesh, Houston Methodist Hosp, Houston, TX; Jeffrey W Moses, Nicholas Lembo, Manish A Parikh, Columbia Univ, New York, NY; Ajay Kirtane, Columbia Univ Medical Ctr, New York, NY; Ziad A Ali, Gkargkoulas Fotios, Columbia Univ, New York, NY; Allison B Hall, Minneapolis Heart Inst, Minneapolis, MN; Evangelia Vemmou, Ilias Nikolakopoulos, Minneapolis Heart Inst and Minneapolis Heart Inst Fndn, Minneapolis, MN; Bavana V Rangan, Dallas VA Medical Ctr, Dallas, TX; Shuaib M Abdullah, N Texas VA Medical Ctr, Dallas, TX; Santiago Garcia, Minneapolis Heart Inst, Edina, MN; Subhash Banerjee, Dallas VA Medical Ctr, Dallas, TX; M Nicholas Burke, Emmanouil S Brilakis, Minneapolis Heart Inst, Minneapolis, MN

12:30 PM

Board # 4146

Impact of Subintimal Tracking for Recanalization of CTO Lesions on Long Term Clinical Outcomes

**Seiji Kano** , Kenya Nasu, Maoto Habara, Toyohashi Heart Ctr, Toyohashi, Japan; Takahiko Suzuki, Toyohashi Heart Ctr, Toyahashi, Japan

# Abstract Poster Session

## HF.APS.14 - Heart Failure and Cardiomyopathies II

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2206

Rapid Neurological Recovery Predicts Survival in Out-of-hospital Cardiac Arrest (ohca) Due to Acute Ischemia, Regardless of Ecg Pattern

**Amir J Khan** , Advocate Illinois Masonic Medical, Chicago, IL; Carmen Jan Liao, Advocate Illinois Masonic Med Cent, Chicago, IL; Anahita Shahrrava, Advocate Illinois Masonic Medical, Skokie, IL; Christopher Kabir, Advocate Health Care, Chicago, IL; Mohammed Samee, Advocate Illinois Masonic Medical Ctr, Chicago, IL; Lloyd Klein, Rush Univ, Chicago, IL

12:30 PM

Board # 2207

The Renal Resistive Index Has a Differential Impact on Future Cardiovascular Events in Atherosclerotic Cardiovascular Patients According to Ejection Fraction

**Praew Kotruchin** , Khon Kaen Univ, Khon Kaen, Thailand; Satoshi Hoshide, Hiromi Ueno, Hayato shimizu, Takahiro Komori, Jichi Medical Univ, Tochigi, Japan; Kazuomi Kario, Jichi Medical Univ, Tochigi-Ken, Japan

12:30 PM

Board # 2208

Altered Cardiac Response of Nitric Oxide and cGMP After Heart Failure--Assessment by Pressure-Volume Analysis

**Xiaowei Zhang** , Che Ping Cheng, Peng Zhou, Zhi Zhang, Satoshi Masutani, Michael F Callahan, Dalane Kitzman, David Herrington, Heng-Jie Cheng, Wake Forest Sch of Med, Winston-Salem, NC

12:30 PM

Board # 2209

1-year High-intensity Exercise Training Reverses Abnormal Left Ventricular Myocardial Stiffness in Patients With Stage B HFpEF

**Michinari Hieda** , UT Southwestern Medical Ctr, Dallas, TX; Satyam Sarma, Christopher Hearon, Katrin Dias, James MacNamara, Dean Palmer, UT Southwestern Medical Ctr, Dallas, Dallas, TX; Jose Martinez, Mitchel Samels, Braden Everding, UT Southwestern Medical Ctr, Dallas, TX; Sheryl A Livingston, Margot Morris, UT Southwestern Medical Ctr, Dallas, Dallas, TX; Benjamin D Levine, UT Southwestern Medical Ctr, Dallas, TX

12:30 PM

Board # 2210

Plasma Microrna-145 and -143 Levels Increase Dependent on the Severity of Left Ventricular Dysfunction and Dilation in Patients With Heart Diseases

**Hirotaka Murase** , Gifu Municipal Hosp, Gifu, Japan; Kazuki Heishima, Gifu Univ, Gifu, Japan; Shinji Yasuda, Atsushi Satake, Ryou Yoshizumi, Hisaaki Komaki, Shinya Baba, Tomoki Kubota, Shinsuke Ojio, Gifu Municipal Hosp, Gifu, Japan; Kazuhiko Nishigaki, Gifu Municipal Hosp, Gifu City, Japan; Shingo Minatoguchi, Toshiki Tanaka, Hiroyuki Okura, Yukihiro Akao, Gifu Univ, Gifu, Japan; Shinya Minatoguchi, Gifu Municipal Hosp, Gifu, Japan

12:30 PM

Board # 2212

Prediction of Re-Hospitalization in Patients With Acute Decompensated Heart Failure by the Use of Cardiac Acoustic Biomarkers

**Jun Shitara** , Japan, Bunkyo, Japan; Takatoshi Kasai, Shoichito Yatsu, Azusa Kurita, Hiroki Matsumoto, Juntendo Univ, Tokyo, Japan; Masaru Hiki, Juntendo Univ, tokyo, Japan; Hiroyuki Daida, Juntendo Univ, Tokyo, Japan

12:30 PM

Board # 2213

Long Term Outcomes After Planned and Unplanned Explantation of a Left-Ventricular Assist Device: Call for New Paradigms to Promote Durability of Remission From Stage D Heart Failure

**Michael Foster** , Joyce Wald, Samip Sheth, Michael Ibrahim, Judith Marble, Janell Conroy, Melissa Murphy, Christopher Domenico, Prashanth Vallabhajosyula, Christian Bermudez, Michael Acker, J. Eduardo Rame, Univ of Pennsylvania, Philadelphia, PA

12:30 PM

Board # 2214

Increased Arterial Stiffness Amplifies the Association Between Hemodynamic Stress and Cardiac Overload: The Japan Morning Surge-Home Blood Pressure Study

**Yusuke Ishiyama** , Satoshi Hoshide, Jichi Medical Univ, Shimotsuke, Japan; Kazuomi Kario, Jichi Medical Univ, Tochigi-ken, Japan

12:30 PM

Board # 2215

Clinical Characteristics of Patients With Heart Failure Show a Continuum Across the Spectrum of Left Ventricular Ejection Fraction: A Substudy of the Patient-Centered Care Transitions in Heart Failure Randomized Clinical Trial

Andreas Gevaert, Lab of Cellular and Moelcular Cardiology, Univ of Antwerp, Antwerp, Belgium; Shun Fu Lee, **Harriette G Van Spall** , Population Health Res Inst, McMaster Univ, Hamilton, ON, Canada

12:30 PM

Board # 2216

Detyrosinated Tubulin as Treatment Target in Genetic Heart Disease: Proteomic and Functional Studies in Hypertrophic Cardiomyopathy

Maike Schuldt, Amsterdam UMC, Vrije Univ Amsterdam, Amsterdam, Netherlands; Jiayi Pei, Magdalena Harakalova, Univ Medical Ctr Utrecht, Utrecht, Netherlands; Larissa M Dorsch, Amsterdam UMC, Vrije Univ Amsterdam, Amsterdam, Netherlands; Michal Mokry, Wilhelmina Children's Hosp, Univ Medical Ctr Utrecht, Utrecht, Netherlands; Jaco C Knol, Tang V Pham, Tim Schelfhorst, Sander R Piersma, Amsterdam UMC, Vrije Univ Amsterdam, Amsterdam, Netherlands; Cris G Dos Remedios, Univ of Sydney, Sydney, Australia; Michiel Dalinghaus, Michelle Michels, Erasmus Univ Medical Ctr, Rotterdam, Netherlands; Folkert W Asselbergs, Univ Medical Ctr Utrecht, Utrecht, Netherlands; Connie R Jimenez, Jolanda van der Velden, **Diederik W Kuster** , Amsterdam UMC, Vrije Univ Amsterdam, Amsterdam, Netherlands

12:30 PM

Board # 2217

The 5-HT2A Receptor Antagonist Sarpogrelate Suppresses Pressure Overload-Induced Development of Heart Failure in Mice

**Kana Shimizu** , Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki, Noriyuki Murai, Hiroki Honda, Satoshi Shimizu, Nurmila Sari, Graduate Sch of Integrated Pharmaceutical and Nutritional Sciences, Univ of Shizuoka, Shizuoka, Japan; Hiromichi Wada, Koji Hasegawa, Kyoto Medical Ctr, Natl Hosp Organization, Kyoto, Japan; Tatsuya Morimoto, Graduate Sch of Integrated Pharmaceutical and Nutritional Sciences, Univ of Shizuoka, Shizuoka, Japan

12:30 PM

Board # 2218

**Epigenetic Landscape in** Mybpc3 **Knockout Mice and Effects on Gene Expression**

**Mohammad Bakhtiar Hossain** , Zaher Elbeck, Xidan Li, Humam Siga, Ralph Knoll, ICMC, Karolinska Instt, Huddinge, Sweden

# Abstract Poster Session

## HF.APS.17 - Heart Failure Biomarkers

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2241

Serum Albumin and Incident Heart Failure: Insights From Epidemiological and Mendelian Randomization Studies

**Xiaodong Zhuang** , First Affiliated Hosp, Sun Yat-Sen Univ, Guangzhou, China; Lizhen Liao, Guangdong Pharmaceutical Univ, Guangzhou, China; Shaozhao Zhang, Xinxue Liao, First Affiliated Hosp, Sun Yat-Sen Univ, Guangzhou, China

12:30 PM

Board # 2242

Parathyroid Hormone as Predictor of Cardiac Function and Outcome in Individuals With Heart Failure - Results From the MyoVasc Study

**Felix Müller** , Marc W Heidorn, Sven Oliver Troebs, Iris Hermanns, Stefanie Steck, Soeren Schwuchow-Thonke, Andreas Schulz, Sebastian Göbel, Marina Panova-Noeva, Bianca Wagner, Thomas Koeck, Steffen Rapp, Karl J Lackner, Tommaso Gori, Thomas Münzel, Philipp S Wild, Jürgen H. Prochaska, Univ Medical Ctr of the Johannes Gutenberg-Univ Mainz, Mainz, Germany

12:30 PM

Board # 2243

Circulating Levels of a Type VI Collagen Formation Biomarker (PRO-C6) are Prognostic for Risk of Hospitalization and Mortality in Patients With HFpEF - Results From the TRAINING-HF Cohort

**Alexander Lynge Reese-Petersen** , Nordic Bioscience, Herlev, Denmark; Patricia Palau, Eloy Dominguez, Hosp General de Castellón, Castellon, Spain; Morten Asser Karsdal, Federica Genovese, Nordic Bioscience, Herlev, Denmark; Julio Nunez, Hosp Clinico Univrio, Valencia, Spain

12:30 PM

Board # 2245

Cardiac Bridging Integrator 1 Score Identifies Ambulatory Heart Failure With Reduced Ejection Fraction Patients and Predicts Cardiovascular Events

**Tara Christine Hitzeman** , Yu Xie, Cedars-Sinai Medical Ctr, Los Angeles, CA; Ronit Zadikany, Andriana Nikolova, Cedars-Sinai Medical Ctr, W Hollywood, CA; Rachel Baum, Ana-Maria Caldaruse, Cedars-Sinai Medical Ctr, Los Angeles, CA; Sosse Agvanian, Cedars-Sinai Medical Ctr, W Hollywood, CA; Gil Melmed, Dermot T McGovern, Dael Ron Geft, David H Chang, Cedars-Sinai Medical Ctr, Los Angeles, CA; Jaime Moriguchi, Antoine Hage, Babak Azarbal, Cedars-Sinai Heart Inst, Beverly Hills, CA; Lawrence S Czer, Cedars-Sinai Medical Ctr, Los Angeles, CA; Michelle M Kittleson, Smidt Heart Inst Cedars-Sinai, Los Angeles, CA; Jignesh K Patel, Smidt Cedars-Sinai Heart Inst, Beverly Hills, CA; Alan H Wu, Univ of California, San Francisco, CA; Jon A Kobashigawa, Cedars-Sinai Heart Inst, Los Angeles, CA; Michele Ann Hamilton, Cedars-Sinai Heart Inst, Beverly Hills, CA; TingTing Hong, Cedars-Sinai Medical Ctr, West Hollywood, CA; Robin M Shaw, Cedars-Sinai Medical Ctr, Los Angeles, CA

12:30 PM

Board # 2246

Penalized Regression Defines a Composite Marker for Risk Stratification in Heart Failure With Reduced Ejection Fraction in the Penn Heart Failure Study (phfs)

**Ron Ammar** , Bristol-Myers Squibb, Princeton, NJ; Michael Basso, Bristol-Myers Squibb, Pennington, NJ; Samuel E Hellings III, Bristol Myers Squibb, Pennington, NJ; Abraham Apfel, Bristol-Myers Squibb, Princeton, NJ; Terrye Delmonte, BMS, Pennington, NJ; Karl Kammerhoff, Bristol-Myers Squibb, Princeton, NJ; Jeffrey A Brandimarto, Univ of Pennsylvania, Philadelphia, PA; Yi Jia, SomaLogic, Inc., Boulder, CO; Joseph D Szustakowski, Bristol-Myers Squibb, Princeton, NJ; David A Gordon, Bristol Myers Squibb Company, Doylestown, PA; Bruce D Car, John R Thompson, Bristol-Myers Squibb, Princeton, NJ; Lei Zhao, Bristol Myers Squibb, Pennington, NJ; Julio A Chirinos, Univ of Pennsylvania, Philadelphia, PA; Thomas P Cappola, Univ Pennsylvania Sch of Med, Philadelphia, PA

12:30 PM

Board # 2247

Proteomic Biomarkers of Risk in Patients With Heart Failure and Reduced Ejection Fraction: Insights From the Penn Heart Failure Study (phfs)

**Ron Ammar** , Bristol-Myers Squibb, Princeton, NJ; Michael Basso, Bristol-Myers Squibb, Pennington, NJ; Samuel E Hellings III, Bristol Myers Squibb, Pennington, NJ; Abraham Apfel, Bristol-Myers Squibb, Princeton, NJ; Terrye Delmonte, BMS, Pennington, NJ; Karl Kammerhoff, Bristol-Myers Squibb, Princeton, NJ; Jeffrey A Brandimarto, Univ of Pennsylvania, Philadelphia, PA; Yi Jia, SomaLogic, Inc., Boulder, CO; Joseph D Szustakowski, Bristol-Myers Squibb, Princeton, NJ; David A Gordon, Bristol Myers Squibb Company, Doylestown, PA; Bruce D Car, John Thompson, Bristol-Myers Squibb, Princeton, NJ; Lei Zhao, Bristol Myers Squibb, Pennington, NJ; Julio A Chirinos, Univ of Pennsylvania, Philadelphia, PA; Thomas P Cappola, Univ Pennsylvania Sch of Med, Philadelphia, PA

12:30 PM

Board # 2250

Type I and Type II Heart Failure Defined: Novel Phenotypes Utilizing the Natriuretic Peptides and Cyclic Guanosine Monophosphate

Jacob J Schaefer, Seethalakshmi R Iyer, **Yang Chen** , Jeson Sangaralingham, John C Burnett Jr., Mayo Clinic, Rochester, MN

# Abstract Poster Session

## HF.APS.12 - Heart Failure Pathophysiology I

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2186

Identifying Unique Proteo-Transcriptomic Profiles of Fibroblasts in the Failing vs Non-Failing Human Sinoatrial Node

**Anuradha Kalyanasundaram** , Ning Li, Ohio State Univ, Columbus, OH; Brian Hansen, Katelynn Helfrich, The Ohio State Univ, Columbus, OH; Miranda L Gardner, Paul Ml Janssen, Ohio State Univ, Columbus, OH; Peter J Mohler, The Ohio State Univ Med Ctr, Columbus, OH; Nahush Mokadam, Bryan Whitson, Mike Freitas, Ohio State Univ, Columbus, OH; Federica Accornero, 7455 Gardengate Place, Dublin, OH; Vadim V Fedorov, The Ohio State Univ, Columbus, OH

12:30 PM

Board # 2187

Acute Inhibition of CaMKII Over-Activation Augments Cardiomyocyte Contractility and Improves β-Adrenergic Regulation in Experimental Diabetic Cardiomyopathy

**Yixi Liu** , Heng-Jie Cheng, Alexei V Mikhailov, Jen-Jar Lin, Peng Zhou, David Zhao, David Herrington, Dalane Kitzman, Che Ping Cheng, Wake Forest Sch of Med, Winston-Salem, NC

12:30 PM

Board # 2188

Cardiac Mlc2 Kinase Is Localized To The Z-disc And Interacts With α-actinin2

**Lawrence Cai** , Univ Florida, Gainesville, FL; Yohei Tanada, Univ of Florida, Gainesville, FL; Gregory Bello, Univ Florida, Gainesville, FL; James Fleming, UF Coll of Med, Gainesville, FL; Fariz Alkassis, Univ Florida, Gainesville, FL; Sixue Chen, Univ of Florida, Gainesville, FL; Hideko Kasahara, Univ Florida, Gainesville, FL

12:30 PM

Board # 2189

Rare Progression From Hypertensive Left Ventricular Hypertrophy to Left Ventricular Dilation Without New Infarction or Other Structural Heart Disease

**Griffin Bullock** , Timothy E Thayer, Eric Farber-Eger, Brandon Lowery, Quinn WELLS, Lynne Warner Stevenson, Vanderbilt Univ Medical Ctr, Nashville, TN

12:30 PM

Board # 2190

**Increase in [ip** 3 **]** I **Aggravates Diastolic [ca** 2+ **] and Exacerbates Contractile Function in Chagas' Human Cardiomyocytes**

Jose R Lopez, Mount Sinai Medical Ctr, Miami Beach, FL; Alfredo Mijares, Insto Venezolano de Investigaciones Cientificas, Caracas, Venezuela, Bolivarian Republic of; Raul Espinoza, Hosp Miguel Perez Carreno, Caracas, Venezuela, Bolivarian Republic of; **Jose Antonio Adams** , Mount Sinai Medical Ctr, Miami Beach, FL

12:30 PM

Board # 2191

Changes in Plasma Hemopexin Are Inversely Associated With Myocardial Strain in Breast Cancer Patients Treated With Anthracyclines

**Aarti Asnani** , Beth Israel Deaconess Medical Ctr, Boston, MA; Debby Ngo, Beth Israel Deaconess, Boston, MA; Qiong Yang, Boston Univ, Boston, MA; Mark Benson, Beth Israel Deaconess Medical Cente, Boston, MA; Sumita Sinha, Dongxiao Shen 02115, Beth Israel Deaconess Medical Ctr, Boston, MA; Igal Sebag, Sir Mortimer B. Davis Jewish General Hosp, Montreal, QC, Canada; Juan C Plana, Baylor Coll of Med, Houston, TX; Marielle Scherrer-Crosbie, Univ of Pennsylvania, Philadelphia, PA; Robert E Gerszten, Beth Israel Deaconess Medical Cente, Boston, MA

12:30 PM

Board # 2192

Increased Capacity to Utilize Ketone Bodies in Patients With Heart Failure: Transmyocardial Gradient Study After Oral Administration of 3-hydroxybutyrate Ester

**Luca Monzo** , "Sapienza" Univ, Rome, Italy; Kamil Sedlacek, Katerina Hromanikova, Lucie Tomanova, Petr Stavek, Antonin Jabor, Janka Franekova, Ivana Kuklova, Inst of Clinical and Experimental Med (IKEM), Prague, Czech Republic; Francesco Barillà, Carlo Gaudio, "Sapienza" Univ, Rome, Italy; Josef Kautzner, Vojtech Melenovsky, Inst of Clinical and Experimental Med (IKEM), Prague, Czech Republic

12:30 PM

Board # 2193

B-arrestin 2 Is Critical For Maintaining Normal Cardiac Function In Aged Mice

**Paola Cecilia Rosas** , Andrielle Capote, Shamin A.K. Chowdhury, Yocelin B Bello, UIC, Chicago, IL; R John Solaro, Univ of Illinois at Chic, Chicago, IL; Beata M Wolska, Univ of Illinois at Chicago, Chicago, IL

12:30 PM

Board # 2194

Dysregulation of Glucose Transport in Left Ventricular Myocardium of Dogs With Chronic Heart Failure

**Hani N Sabbah** , Ramesh C Gupta, Vinita Singh-Gupta, David E Lanfear, Henry Ford Hosp, Detroit, MI

12:30 PM

Board # 2195

Ebselen, a Divalent Metal Transporter 1 Inhibitor, Effectively Blocks Iron Entry to Human Ipsc-Derived Cardiomyocytes and Prevents Iron-Overload Cardiotoxicity

**June-wha Rhee** , Hyoju Yi, Stanford Univ Medical Ctr, Stanford, CA; Chi Keung Lam, Stanford Univ, Stanford, CA; Nadjet Belbachir, Stanford Univ Medical Ctr, Stanford, CA; Lei Tian, Stanford Cardiovascular Inst, Stanford, CA; Dilip Thomas, Edward Lau, David T Paik, Stanford Univ, Palo Alto, CA; Maggie P Lam, Univ of Colorado Denver, Los Angeles, CA; Nazish Sayed, Stanford Univ, Stanford, CA; Karim Sallam, Stanford, Stanford, CA; Joseph C Wu, Stanford Univ Sch of Med, Stanford, CA

# Abstract Poster Session

## HF.APS.10 - HFpEF

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2166

Myocardium in Heart Failure With Preserved Ejection Fraction is Less Compressible Than Normal Myocardium

**Vinayak Kumar** , Alexander Ryu, Armando Manduca, Nandan S Anavekar, Mayo Clinic, Rochester, MN

12:30 PM

Board # 2168

Prolonged Accumulation of Macrophages in Endo-Myocardial Biopsies After Remission of Heart Failure With Preserved Ejection Fraction

**Hiroyuki Takahama** , Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Yasuo Sugano, Div of Cardiovascular Med, Keiyu Hosp, Yokohama, Japan; Keiko Ogo, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Yasuhiro Hamatani, Natl Cerebral and Cardiovascular Ct, Osaka, Japan; Masashi Amano, Atsushi Okada, Makoto Amaki, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Takuya Hasegawa, Natl Cerebral and Cardiovascular Ctr, Suita Osaka, Japan; Hideaki Kanzaki, Natl Cardiovascular Ctr, Osaka, Japan; Toshihisa Anzai, Hokkaido Univ, Sapporo, Japan; Satoshi Yasuda, Natl Cerebral and Cardiovascular Ctr, Osaka, Japan; Hatsue Ishibashi-Ueda, Chisato Izumi, Natl Cerebral and Cardiovascular Ctr, Suita, Japan

12:30 PM

Board # 2169

Nitric Oxide-mediated Coronary Endothelial Function Is Impaired In Patients With Heart Failure With Preserved Ejection Fraction

**Sabra C Lewsey** , Allison G. Hays, Johns Hopkins Univ Sch of Med, Baltimore, MD; Michael Schär, Johns Hopkins Univ, Baltimore, MD; Gabriele Bonanno, Gary Gerstenblith, Robert G. Weiss, Johns Hopkins Univ Sch of Med, Baltimore, MD

12:30 PM

Board # 2170

The Prognostic Impact of Geometric Types and Its Shift in Patients With Heart Failure With Preserved Ejection Fraction: Insight From the Pursuit-hfpef Registry

**Hiroyoshi Yamamoto** , Osaka Minato Central Hosp, Osaka, Japan; Yasumura Yoshio, Amagasaki Chuo Hosp, Amagasaki, Japan; Takahisa Yamada, Osaka General Medical Ctr, Osaka, Japan; Masaaki Uematsu, Osaka Natl Hosp, Osaka, Japan; Shunsuke Tamaki, Osaka General Medical Ctr, Osaka, Japan; Yoshiharu Higuchi, Osaka Police Hosp, Osaka, Japan; Nakagawa Yusuke, Kawanishi City Hosp, Kawanishi, Japan; Fuji Hisakazu, Kobe Ekisaikai Hosp, Kobe, Japan; Masami Nishino, Osaka General Medical Ctr, Sakai Osaka, Japan; Shungo Hikoso, Daisaku Nakatani, Yasushi Sakata, Osaka General Medical Ctr, Suita, Japan; PURSUIT-HFpEF investigators

12:30 PM

Board # 2171

Mid- To Late-life Systemic Inflammation and Incidence of Heart Failure With Preserved (HFpEF) and Reduced Ejection Fraction (HFrEF) in Late-Life: The Atherosclerosis Risk in Communities (ARIC) Study

**Aaron J Cohen** , Kanako Teramoto, Jenine E John, Brian Claggett, Leo F Buckley III, Scott D Solomon, Brigham and Women's Hosp, Boston, MA; Christie M Ballantyne, Baylor Coll of Med, Houston, TX; Elizabeth Selvin, Johns Hopkins Univ, Baltimore, MD; Amil M Shah, Brigham and Women's Hosp, Boston, MA

12:30 PM

Board # 2172

Heart Failure With Preserved Ejection Fraction: Phenotypic Differences Between Diabetic and Non Diabetic Patients

Sibille Lejeune, Cliniques Univires Saint-Luc, Brussels, Belgium; Clotilde Roy, Alisson France Slimani, Cliniques Univires Saint-Luc, Bruxelles, Belgium; David Vancraeynest, Cliniques Univires Saint-Luc, Brussels, Belgium; Agnes A Pasquet Jr., Cliniques Univires Saint-Luc, Bruxelles, Belgium; Christophe Beauloye, IREC - UCL, Brussels, Belgium; Jean-louis Vanoverschelde, Cliniques Univires Saint-Luc, Brussels B, Belgium; Bernhard L Gerber, **Anne Catherine Pouleur** , Cliniques Univires Saint-Luc, Brussels, Belgium

12:30 PM

Board # 2173

The Impact of Heart Rate Reserve at Discharge on Prognosis in Patients With Heart Failure With Preserved Ejection Fraction

**Masato Okada** , Toshinari Onishi, Koichi Inoue, Katsuomi Iwakura, Sakurabashi Watanabe Hosp, Osaka, Japan; Yasumura Yoshio, Amagasaki Chuo Hosp, Amagasaki, Japan; Takahisa Yamada, Osaka General Medical Ctr, Osaka, Japan; Uematsu Masaaki, Natl Hosp Organization Osaka Natl Hosp, Osaka, Japan; Shunsuke Tamaki, Osaka General Medical Ctr, Osaka, Japan; Yoshiharu Higuchi, Osaka Police Hosp, Osaka, Japan; Nakagawa Yusuke, Kawanishi City Hosp, Kawanishi, Japan; Fuji Hisakazu, Kobe Ekisaikai Hosp, Kobe, Japan; Masami Nishino, Osaka Rosai Hosp, Sakai, Japan; Shungo Hikoso, Daisaku Nakatani, Yasushi Sakata, Osaka Univ Grad Sch of Med, Suita, Japan

12:30 PM

Board # 2174

Impact of Chronic Obstructive Pulmonary Disease in Heart Failure With Preserved Ejection Fraction

**Mary Jo Obeid** , Univ of Pennsylvania, Philadelphia, PA; Snigdha Jain, UT Southwestern Medical Ctr, Dallas, TX; Jonathan Lee, Univ of Pennsylvania, Philadelphia, PA; Sowjanya Yenigalla, UPMC, Pittsburgh, PA; Armghan H Ans, Garrett Oldland, Jessica Koshinski, Univ of Pennsylvania, Philadelphia, PA; Zeba Hashmath, Saint Vincent Hosp, Worcester, MA; Gurpreet Singh, Univ of Pennsylvania, Philadelphia, PA; Vaibhav Satija, St Vincent's Hosp, Worcester, MA; Scott Akers, Philadelphia VAMC, Philadelphia, PA; Julio A Chirinos, Univ of Pennsylvania, Philadelphia, PA

12:30 PM

Board # 2175

The Importance of Non-Cardiac Comorbidities in Hospitalized Heart Failure With Preserved Ejection Fraction - A Secondary Analysis of Heart Failure Network Trials

**Yogesh N. V. Reddy** , Masaru Obokata, Mayo Clinic, Rochester, MN; Aaron D Jones, Duke Clinical Res Inst, Durham, NC; Omar AbouEzzedine, Mayo Clinic, Rochester, MN; Marat Fudim, Duke, Durham, NC; Brooke Alhanti, Duke Univ, Durham, NC; Lynne Warner Stevenson, Vanderbilt Univ Medical Cente, Nashville, TN; Margaret M Redfield, Barry A Borlaug, MAYO CLINIC, Rochester, MN

# Abstract Poster Session

## IN.APS.08 - Hot Topics in TAVR and Structural Interventions

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4148

Transcatheter versus Surgical Aortic Valve Replacement on Outcomes in Patients With and Without Atrial Fibrillation

**Kranthi K Sitammagari** , Atrium Health, Monroe, NC; Paula Strassle, Univ of North Carolina at Cha, Carrboro, NC; Sameer Arora, Univ of North Carolina, Chapel Hill, NC; Arman Qamar, Brigham and Women's Hosp, Boston, MA; Cassandra J Ramm, Univ of North Carolina Sch of Med, Chapel Hill, NC; Madhu B Paladugu, Campbell Univ Sch of Osteopathic Med, Lillington, NC; Michael Yeung, Univ of North Carolina Sch of Med, Chapel Hill, NC; John Paul Vavalle, Univ of North Carolina, Chapel Hill, NC

12:30 PM

Board # 4149

Impact of Aortic Valve Calcification on Acute Elastic Recoil of a Balloon-Expandable Valve After Transcatheter Aortic Valve Replacement

**Nagataka Yoshihara** , Hirokuni Akahori, Takamasa Tanaka, Koji Yanaka, Toshio Kimura, Kojiro Miki, Takahiro Imanaka, Masaharu Ishihara, Hyogo Coll of Med, Nishinomiya, Japan

12:30 PM

Board # 4150

Cost-Effectiveness of Transcatheter versus Surgical Aortic Valve Replacement in Low-Risk Patients With Severe Aortic Stenosis

**Jennifer Y Zhou** , Alfred Hosp, Melbourne, Australia; Danny Liew, Monash Univ, Melbourne, Australia; Stephen J Duffy, Antony Walton, Nay Htun, Dion Stub, Alfred Hosp, Melbourne, Australia

12:30 PM

Board # 4151

Impact of Left Atrial Pressure on Long-Term Outcomes in Patients With Mitraclip Therapy

**Hiroki Niikura** , Mario Gössl, Richard Bae, Paul Sorajja, Minneapolis Heart Inst, Minneapolis, MN

12:30 PM

Board # 4152

Augmented Reality Guidance for Transcatheter Septal Puncture Procedure in Structural Heart Interventions

**Sun-Joo Jang** , Jun Liu, Gurpreet Singh, Subhi J. Al'Aref, Alexandre Caprio, Amir Ali Amiri Moghadam, Shing-Chiu Wong, James K Min, Simon Dunham, Bobak Mosadegh, NewYork-Presbyterian Hosp and Weill Cornell Med, New York, NY

12:30 PM

Board # 4153

Cost-effectiveness of Combined Atrial Fibrillation Ablation and Left Atrial Appendage Closure in Patients With High Stroke and Bleeding Risk

**Hiroshi Kawakami** , Mark T Nolan, Baker Heart and Diabetes Inst, Melbourne, Australia; Karen Phillips, Greenslopes Hosp, Brisbane, Australia; Thomas H Marwick, Baker Heart and Diabetes Inst, Melbourne, Australia

12:30 PM

Board # 4155

Inflammatory Phenotypes of Circulating Leukocyte Subsets Are Associated With Increased Mortality After Transfemoral Transcatheter Aortic Valve Implantation

**Jedrzej Hoffmann** , Univ Hosp Frankfurt, Frankfurt, Germany; Silvia Mas-Peiro, Universtity Hosp, Frankfurt am Main; Felicitas Boeckling, Univ Hosp Frankfurt, Frankfurt, Germany; Tina Rasper, Inst for Cardiovascular Regeneration, Frankfurt, Germany; Alexander Berkowitsch, Univ Hosp Frankfurt, Frankfurt, Germany; Konrad Pieszko, Nowa Sol Multidisciplinary Hosp, Nowa Sol, Poland; Stephan Fichtlscherer, Johann W. Goethe Univ, Frankfurt, Germany; Andreas M Zeiher, Klinikum d. J. W Goethe-Univ, Frankfurt Am Main; Stefanie Dimmeler, Inst of Cardiovasular Regeneration, Frankfurt Am Main, Germany; Mariuca Vasa-Nicotera, Univ Hosp Frankfurt, Frankfurt, Germany

12:30 PM

Board # 4156

Right Heart Dysfunction and Clinical Outcomes in Patients With Severe Mitral Regurgitation Undergoing Mitraclip

**Rashad Jabali Belin** , Travis Desa, Loyola Univ Medical Ctr, Maywood, IL; Igor Wroblewski, Ramon Durazo-Arvizu, Zion, IL; Lowell H Steen, John J Lopez, Loyola Univ Medical Ctr, Maywood, IL; Bruce Lewis, Loyola Univ Medical Ctr, AL; Fred Leya, Verghese Mathew, Loyola Univ Medical Ctr, Maywood, IL

12:30 PM

Poster Professor

Hani Jneid, Houston, TX

# Abstract Poster Session

## QU.APS.02 - Improving Outcomes in Atrial Fibrillation

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 3222

Predictors of Subclinical Atrial Fibrillation Detected by Insertable Cardiac Monitors as Identified by a Patient-level Meta-analysis of the Reveal AF, Assert II, and Predate AF Clinical Trials Datasets

**James A Reiffel** , Columbia Univ, Jupiter, FL; Jia Wang, McMaster Univ, Hamilton, ON, Canada; Jay Nasir, Stanford Univ, Stanford, CA; Paul D Ziegler, Medtronic, Inc, Mounds View, MN; Marco Alings, Amphia Ziekenhus, Breda, Netherlands; Erika Pouliot, Medtronic Inc., Mounds View, MN; Jeffrey Healey, McMaster Univ, Hamilton, ON, Canada; The REVEAL AF, ASSERT II, and PREDATE AF Investigators

12:30 PM

Board # 3223

Effectiveness and Safety of Rivaroxaban versus Warfarin in Patients With Non-Valvular Atrial Fibrillation (NVAF) and Stage IV-V Chronic Kidney Disease (CKD) as Determined by Cockcroft-Gault (CG) and Modification of Diet in Renal Disease (MDRD) Equations

Matthew R Weir, Univ of Maryland Sch of Med, Baltimore, MD; **Veronica Ashton** , Janssen Scientific Affairs LLC, Titusville, NJ; Eric M. Ammann, Janssen Scientific Affairs, LLC, Titusville, NJ; Kenneth T. Moore, Janssen Medical Affairs, Titusville, NJ; Shubham Shrivastava, Mu Sigma, Bangalore, India; Eric D Peterson, Duke Univ Sch of Med, Durham, NC

12:30 PM

Board # 3224

Stroke Prophylaxis After US Emergency Department Diagnosis and Discharge of Patients With Atrial Fibrillation and Flutter

**Bory Kea** , Oregon Health & Science Univ, Portland, OR; E. Margaret E Warton, Kaiser Permanente, Oakland, CA; Benjamin C Sun, Univ of Pennsylvania, Philadelphia, PA; Brian Olshansky, Univ of Iowa, Mason City, IA; Gregory Y H Lip, Univ of Liverpool, Liverpool, United Kingdom; Merritt Raitt, Portland VA Medical Ctr, Portland, OR; Mary E Reed, Kaiser Permanente, Oakland, CA; Dustin W Ballard, The Permanente Medical Group, Oakland, CA; David R Vinson, The Permanente Medical Group, Roseville, CA; on behalf of the KP CREST Network

12:30 PM

Board # 3225

Patient Characteristics, Care Patterns, and Outcomes of Atrial Fibrillation Associated Hospitalizations in Patients With Chronic Kidney Disease and End-stage Renal Disease

**Nilay Kumar** , Univ of Wisconsin Sch of Med and Public Health, Madison, WI; Haolin Xu, Roland Matsouaka, Duke Clinical Res Inst, Durham, NC; Neetika Garg, Univ of Wisconsin Sch of Med and Public Health, Madison, WI; Ambarish Pandey, UTSW Medical Ctr, Dallas, TX; Jonathan P Piccini, Duke Univ Medical Ctr, Durham, NC; William R Lewis, The MetroHealth System, Cleveland, OH; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA

12:30 PM

Board # 3226

Quality of Life Outcomes After Catheter Ablation Among Patients With Atrial Fibrillation in the Real World Practice

**Nobuhiro Ikemura** , Takehiro Kimura, Ikuko Ueda, Keio Univ Sch of Med, Tokyo, Japan; Hiroshi Miyama, Taishi Fujisawa, Yoshinori Katsumata, Keio Univ Hosp, Tokyo, Japan; Keiichi Fukuda, Keio Univ, Tokyo, Japan; Seiji Takatsuki, Keio Univ Sch of Med, Tokyo, Japan; Shun Kohsaka, Keio Univ, Tokyo, Japan

12:30 PM

Board # 3227

Mild Depression Worsens Disease-specific Quality of Life and Psychological Stress in Atrial Fibrillation

**Brittany Gisi** , Andrew D. Althouse, Abigail S Mathier, Alexandra M Pusateri, Jared W Magnani, Anna LaRosa, Bruce L Rollman, Univ of Pittsburgh, Pittsburgh, PA

12:30 PM

Board # 3228

Readability Assessment of Online Patient Education Materials on Atrial Fibrillation

**Emaad Siddiqui** , Aakash Shah, Alfonso H Waller, Justin Sambol, Rutgers New Jersey Medical Sch, Newark, NJ

12:30 PM

Board # 3230

Postoperative Opioid Prescription Patterns and New Opioid Refills Following Cardiac Implantable Electronic Device Procedures

**Justin Z Lee** , Mayo Clinic, Rochester, MN; Ahmed K Pasha, Mayo Clinic Health System, North Mankato, MN; Amy E Glasgow, Elzabeth B Habermann, Mayo Clinic, Rochester, MN; Fred Kusumoto, Mayo Clinic, Jacksonville, FL; Christopher J McLeod, Mayo Clinic, Rochester, MN; Vasudha Goel, Univ of Arizona, Tucson, AZ; Dan Sorajja, Komandoor Srinivasan Srivathsan, Win K Shen, Mayo Clinic, Phoenix, AZ; Malini Madhavan, Abhishek Deshmukh, Yong-mei Cha, Paul Friedman, Mayo Clinic, Rochester, MN; Samuel Asirvatham, Mayo Fndn, Rochester, MN; Siva K Mulpuru, Mayo Clinic, Rochester, MN

# Abstract Poster Session

## HF.APS.18 - Insights into Cardiomyopathy

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2251

Diagnostic Value of a Subjective Functional Score (i.e. Perceived Functional Capacity) Among Patients With Hypertrophic Cardiomyopathy

**Kristyn N McLeod** , Jeffrey B Geske, Mayo Clinic, Rochester, MN; Rick A Nishimura, Mayo Clinic Rochester, Rochester, MN; Thomas G Allison, Darrell Brian Newman, Mayo Clinic, Rochester, MN

12:30 PM

Board # 2252

Wrap Around Left Anterior Descending Coronary Artery in Stress Induced Cardiomyopathy: Fiction, or Reality ?

**Byung-il William Choi** , Jee Min, Katheryn Umhoefer, Medical Coll Wisconsin, Milwaukee, WI

12:30 PM

Board # 2253

Transmethylamine-N-oxide (TMAO) is Associated With Diffuse Cardiac Fibrosis in Persons Living With HIV

**Nalini A Colaco** , Yifei Ma, UCSF, San Francisco, CA; Rebecca Scherzer, SFVA, San Francisco, CA; Olga Ilkayeva, Patrice Desvigne-Nickens, Duke, Durham, NC; Eugene Braunwald, Brigham and Women's Hosp, Boston, MA; Javed Butler, Emory, Atlanta, GA; Svati H Shah, Duke Univ Medical Ctr, Hillsborough, NC; Sanjiv J Shah, Northwestern Univ, Chicago, IL; Priscilla Hsue, Univ of California, San Francisco, CA

12:30 PM

Board # 2254

Sirt6 Protects the Heart From Aging-induced Cardiac Hypertrophy by Enhancing Mitochondrial Fitness

Vinodkumar Pillai, Univ Chicago, Chicago, IL; Sadhana A Samant, The Univ of Chicago, Chicago, IL; Madhu Gupta, **Mahesh P Gupta** , Univ Chicago, Chicago, IL

12:30 PM

Board # 2255

Prevalence and Prognosis of Right Ventricular Mechanical Dysfunction in Patients With Hypertrophic Cardiomyopathy

**Jiwon Seo** , Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Shinjeong Song, Yonsei Univ Coll of Med, Seoul; Purevjargal Lkhagvasuren, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Chi Young Shim, Yonsei Univ Coll of Med, Seoul; Geu-Ru Hong, Yonsei Univ, Seoul; Jong-Won Ha, Yonsei Univ Coll of Med, Seoul

12:30 PM

Board # 2256

Pluripotent Stem Cell-derived Cardiomyocytes From a Patient With Arg723gly β-myosin Heavy Chain Mutation Show Alterations in Twitch Contractions, Calcium Transients and Highly Variable Allele Specific Expression of Mutant/wildtype β-myosin Heavy Chain Mrna

**Natalie Weber** , Tim Holler, Joachim Meissner, Judith Montag, Neele Peschel, Anne Kathrin Mayer, Kristin Schwanke, Birgit Piep, Ulrich Martin, Robert Zweigerdt, Theresia Kraft, Hannover Medical Sch, Hannover, Germany

12:30 PM

Board # 2257

Correlation of Technetium Pyrophosphate Uptake With Cardiac Amyloid Load, Native T1, and Extracellular Volume in Patients With Transthyretin Cardiac Amyloidosis

**Mami Morioka** , Seiji Takashio, Masato Nishi, Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

12:30 PM

Board # 2258

Age-Related Cardiomyopathy in a Transgenic Knock-In Mouse Model of Sickle Cell Disease

**Maureen Mburu** , Samit Ghosh, Xucai Chen, Solomon F Ofori-Acquah, Univ of Pittsburgh, Pittsburgh, PA; Flordeliza S Villanueva, UPMC, Pittsburgh, PA

12:30 PM

Board # 2259

An Automated Natural Language Processing Algorithm to Classify Magnetic Resonance Imaging Reports Containing Positive Diagnoses of Hypertrophic Cardiomyopathy

Sungrim Moon, Elham Sagheb, Sijia Liu, David Chen, Martijn Bos, Jeffrey B Geske, Peter A. Noseworthy, Michael J Ackerman, Jane L. Shellum, Rajeev Chaudhry, Steve R Ommen, Philip A Araoz, Rick A. Nishimura, Hongfang Liu, **Adelaide Arruda-Olson** , Mayo Clinic, Rochester, MN

12:30 PM

Board # 2260

Protection of Acacetin Against Diabetic Cardiomyopathy

**Fei Song** , Xiamen Cardiovascular Hosp, Xiamen Univ, Xiamen, China; Gui-Rong Li, Xiamen Cardiovascular Hosp, Xiamen, China; Yan Wang, Xiamen Cardiovascular Hosp, Xiamen Univ, Xiamen, China

12:30 PM

Poster Professor

April Stempien-otero, Seattle, WA

# Abstract Poster Session

## HF.APS.15 - Insights on HYpertrophic Cardiomyopathy

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2219

No Difference in Timing and Risk for Sudden Death in Women and Men With Hypertrophic Cardiomyopathy

**William Gionfriddo** , Tufts Medical Ctr, Boston, MA; Barry J Maron, Minneapolis Heart Inst Foundat, Swampscott, MA; Christopher Madias, Sophie Wells, Martin S Maron, Ethan J Rowin, Tufts Medical Ctr, Boston, MA

12:30 PM

Board # 2220

Renal Function Contribute to the Future Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy

**Hyemoon Chung** , Kyung Hee Univ Medical Ctr, Seoul, Korea, Republic of; Jong-Youn Kim, Pil-Ki Min, Gangnam Severance Hosp, Seoul, Korea, Republic of; Young Won Yoon, Gangnam Severance Hosp, Yonsei Univ Medical Sch, Seoul, Korea, Republic of; Byoung Kwon Lee, Gangnam Severance Hosp, Seoul; Bum-Kee Hong, Gangnam Severance Hosp, Yonsei Univ Medical Sch, Seoul, Korea, Republic of; Se-Joong Rim, Gangnam Severance Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Hyuck Moon Kwon, Gangnam Severance Hosp, Yonsei Univ Medical Sch, Seoul, Korea, Republic of; Eui-Young Choi, Gangnam Severance Hosp, Seoul, Korea, Republic of

12:30 PM

Board # 2221

Distinct Subgroups in Hypertrophic Cardiomyopathy: Baseline Results From HCMR

Stefan Neubauer, Div of Cardiovascular Med, Oxford; Paul Kolm, MedStar Heart & Vascular Inst, Washington, DC; Carolyn Ho, Brigham and Women's Hosp, Boston, MA; Milind Desai, Cleveland Clinic, Cleveland, OH; Sarahfaye Dolman, MedStar Heart & Vascular Inst, Washington, DC; Evan Appelbaum, Men's Health Ctr, Chestnut Hill, MA; Patrice M Desvigne-nickens, NHLBI, Bethesda, MD; John P Dimarco, Univ Virginia Hosp, Charlottesville, VA; Matthias G Friedrich, Royal Victoria Hosp, Montreal, QC, Canada; Nancy Geller PhD, NHLBI, Bethesda, MD; Michael Jerosch-Herold, Brigham and Women's Hosp, Boston, MA; Dong-Yun Kim, NHLBI, Bethesda, MD; Martin S Maron, Tufts Medical Ctr, Boston, MA; Jeanette Schulz-Menger, Charite Campus Buch, Berlin, Germany; Stefan Piechnik, Univ of Oxford, Oxford, United Kingdom; Cheng Zhang, MedStar Heart & Vascular Inst, Washington, DC; Hugh Watkins, Univ of Oxford, Oxford; William S Weintraub, Medstar Washington Hosp Ctr, Washington, DC; **Christopher M Kramer** , Univ of Virginia Health System, Charlottesville, VA

12:30 PM

Board # 2222

Prognostic Value of Left Ventricular Trabeculae via Fractal Analysis in Patients With Hypertrophic Cardiomyopathy

**Jie Wang** , Yuanwei Xu, Yucheng Chen, West China Hosp, Sichuan Univ, Chengdu, China

12:30 PM

Board # 2223

Sex-based Similarities in Left Ventricular Hypertrophy Regression and Progression

**Arash Nayeri** , UCLA, Los Angeles, CA; Eric Farber-Eger, Vanderbilt Univ Medical Ctr, Nashville, TN; Marcia Blair, Vanderbilt Univ, Nashville, TN; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; Kamran Shamsa, UCLA, Los Angeles, CA; John A McPherson, Quinn WELLS, Vanderbilt Univ, Nashville, TN

12:30 PM

Board # 2224

Elevated Troponin T is an Independent Predictor of Adverse Outcome in Hypertrophic Cardiomyopathy

**Frank Gommans** , Radboud Univ Medical Ctr, Nijmegen, Netherlands; Etienne Cramer, Radboud Univ Medical Ctr,, Nijmegen, Netherlands; Michael Fouraux, Albert Schweitzer Hosp, Nijmegen, Netherlands; Sanne Heijmans, Radboud Univ Medical Ctr, Nijmegen, Netherlands; Michelle Michels, Erasmusmc, Rotterdam, Netherlands; Janneke Timmermans, Radboudumc, Nijmegen, Netherlands; Freek W Verheugt, OLVG, Amsterdam; Rudolf A De Boer, Univ Medical Ctr Groningen, Groningen, Netherlands; Marcel Kofflard, Albert Schweitzer Hosp, Dordrecht, Netherlands; Marc Brouwer, Radboudumc Nijmegen The Netherlands, Nijmegen

12:30 PM

Board # 2225

Sarcomere Gene Mutations Independently Contribute to Left Atrial Myopathy in Patients With Hypertrophic Cardiomyopathy

**Hyemoon Chung** , Kyung Hee Univ Medical Ctr, Seoul, Korea, Republic of; Yoonjung Kim, Chul-Hwan Park, Gangnam Severance Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Jong-Youn Kim, Pil-ki Min, Gangnam Severance Hosp, Seoul, Korea, Republic of; Young Won Yoon, Gangnam Severance Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Byoung Kwon Lee, Gangnam Severance Hosp, Seoul; Bum-Kee Hong, Se-Joong Rim, Hyuck Moon Kwon, Kyung-A Lee, Gangnam Severance Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Eui-young Choi, Gangnam Severance Hosp, Seoul, Korea, Republic of

12:30 PM

Board # 2226

Thick Hearts Can't Keep Up: Patients With Hypertrophic Cardiomyopathy Are Centrally Limited During Submaximal and Maximal Exercise

**Katrin A Dias** , Christopher M Hearon Jr., Michinari Hieda, James P MacNamara, Inst for Exercise and Environmental Med, Texas Health Presbyterian Dallas and Univ of Texas Southwestern Medical Ctr, Dallas, TX; Aslan Turer, Mark S Link, Univ of Texas Southwestern Medical Ctr, Dallas, TX; Satyam Sarma, Benjamin D Levine, Inst for Exercise and Environmental Med, Texas Health Presbyterian Dallas and Univ of Texas Southwestern Medical Ctr, Dallas, TX

12:30 PM

Board # 2227

Gender Differences in Hypertrophic Cardiomyopathy

**Catherina Tjahjadi** , Leiden Univ Medical Ctr, Leiden, Netherlands; Yasmine Lisanne Hiemstra, LUMC, Leiden; Marianne Bootsma, Leiden Univ Medical Ctr, Leiden, Netherlands; Jeroen J Bax, Leids Univ Medisch Centrum, Leiden, Netherlands; Victoria Delgado, Nina Ajmone Marsan, Leiden Univ Medical Ctr, Leiden, Netherlands

12:30 PM

Board # 2228

Primary Prevention of Sudden Cardiac Death in Hypertrophic Cardiomyopathy, Data From the French Society of Cardiology Hospital-Based Register

**Mariana Mirabel** , Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France; Erwan Donal, CHU Rennes, Rennes, France; Offredo Lucile, Inst Natl de la Santé et de la Recherche Médicale, Paris, France; Xavier Jeunemaitre, Hop europeen Georges Pompidou, Paris, France; Patricia Reant, Ctr Hospo-Univire de Bordeaux, Hôpital Haut Levêque, Pessac, France; Albert A. Hagege, Georges Pompidou European Hosp, Paris, France

12:30 PM

Poster Professor

Martin S Maron, Boston, MA

12:30 PM

Board # 2229

In-Hospital Outcomes Following Alcohol Septal Ablation versus Septal Myectomy in Hypertrophic Cardiomyopathy With versus Without Atrial Fibrillation

Rupak Desai, Atlanta VA Medical Ctr, Decatur, GA; Sandeep Singh, Academic Medical Ctr, Amsterdam, Netherlands; **Rushik Bhuva** , Geisinger Wyoming Valley Medical Ctr, Wilkes-Barre, PA; Bishoy Hanna, Morehouse Sch of Med, Atlanta, GA; Upenkumar Patel, Nassau Univ Medical Ctr, East Meadow, NY; Tarang Parekh, George Mason Univ, Fairfax, VA; Kishor Gangani, Texas Health Arlington Memorial, Arlington, TX; Gautam Kumar, Emory Univ & Atlanta VA Medical Ctr, Decatur, GA; Rajesh Sachdeva, Morehouse Sch of Med & Atlanta VA Medical Ctr, Atlanta, GA

12:30 PM

Board # 2230

High Burden Of Ischemic Stroke Is Independent Of Concomitant Atrial Fibrillation In Hypertrophic Cardiomyopathy

**Bharat Narasimhan** , Stuthi Perimbeti, Mount Sinai St.Lukes-Roosevelt, New York, NY; Lingling Wu, Mount Sinai St Luke's and West, New York, NY; Ameesh Isath, Mount Sinai St.Lukes-Roosevelt, Rochester, MN; Kirtipal Singh Bhatia, Mount Sinai St Luke's and West, New York, NY; Kam Ho, Mount Sinai St Luke's and West Hosp, New York, NY; Carlos A Gongora, Mount Sinai West snd St Lukes, New York, NY; Bette Kim, Mount Sinai West, New York, NY

# Abstract Poster Session

## IN.APS.09 - Interventional Controversies from all over the World

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4157

Severe Acute Stent Malapposition Follow-Up: 3-Month and 12-Month Serial Quantitative Analyses by Optical Coherence Tomography

**Sung-Jin Hong** , Chul-Min Ahn, Yonsei Univ Medical Coll, Seoul, Korea, Republic of; Jung-Sun Kim, Yonsei Univ Medical Cent, Seoul, Korea, Republic of; Byeong-Keuk Kim, Yonsei Univ Severance Hospita, Seoul; Young-Guk Ko, Yonsei Cardiovascular Ctr, Seoul; Donghoon Choi, Severance hospital, Seoul; Yangsoo Jang, Yonsei Univ Medical Coll, Seoul, Korea, Republic of; Myeong-Ki Hong, Severance Cardiovascular Hosp, Seoul

12:30 PM

Board # 4159

6-month Readmission and Mortality Differences in DES vs. BMS for STEMI in the Contemporary Era- A Nationwide Analysis

**Aaqib H Malik** , Westchester Medical Ctr, Valhalla, NY; Suchith Shetty, Univ of Iowa, Iowa City, IA; Srikanth Yandrapalli, Westchester Medical Ctr, White Plains, NY; Syed Zaid, Westchester Medical Ctr, Valhalla, NY; Wilbert S Aronow, New York Medical Coll, New Rochelle, NY; Undemir Cenap, Hasan Ahmad, Westchester Medical Ctr, Valhalla, NY

12:30 PM

Board # 4160

Mechanical Thrombectomy by Solotariedevice for Persistent Thrombus in Acute Coronary Syndrome

**Daoyuan Si** , Xingyu Fan, Yaliang Tong, Hongliang Yang, Yuquan He, China-Japan Union Hosp of Jilin, Changchun, China

12:30 PM

Board # 4162

Temporal Change in Coronary Evagination After Implantation of Bioresorbable Polymer Sirolimus-Eluting Stent: An Mechanism-Ultimaster Sub-Study

**Keiko Tsuji** , Masaru Ishida, Tomonori Itoh, Iwate Medical Univ, Morioka, Japan; Hiromasa Otake, Yoshiro Tsukiyama, Kobe Univ, Kobe, Japan; Takumi Kimura, Iwate Medical Univ, Morioka, Japan; Tatsuo Kikuchi, Edogawa Hosp, Higashikoiwa Edogawa-ku Tokyo, Japan; Munenori Okubo, Gihu Heart Ctr, Gihu, Japan; Takatoshi Hayashi, Hyogo Prefectural Awaji Medical Ctr, Sumoto, Japan; Hideto Oda, Iwate Prefectural Miyako Hosp, Miyako, Japan; Yohei Uchimura, Kaduno Kousei Hosp, Kaduno, Japan; Kyosuke Kaneko, Iwate Medical Univ, Morioka, Japan; Tsubasa Sakamoto, Iwate Prefectural Ofunato Hosp, Ofunato, Japan; Yuya Taguchi, Cardiovascular medicine Kurashiki Central Hosp, Kurashiki, Japan; Iwao Goto, Iwate Medical Univercity, Morioka, Japan; Toshiro Shinke, Showa Univ Sch of Med, Tokyo, Japan; Yoshihiro Morino, Iwate Medical Univ, Marioka, Japan

12:30 PM

Board # 4164

Clinical Outcomes in Chronic Total Occlusion Revascularization versus No Chronic Total Occlusion Revascularization: Variability by Target Vessel

**Shen Lin** , Sipeng Chen, Yan Zhao, Fuwai Hosp, Beijing, China; Zhe Zheng, Fuwai Hosp, Beijing; The Beijing Coronary Angiography Registry Collaborative Group

12:30 PM

Board # 4165

Impact of Percutaneous Intervention of Coronary Chronic Total Occlusions on Left Ventricular Ejection Fraction: A Systematic Review and Meta Analysis

**Qasim Malik** , David Prutzman, Peter Puleo, Chris Sarnoski, Raymond Durkin, Jamshid Shirani, St. Luke's Univ Health Network, Bethlehem, PA

12:30 PM

Board # 4166

Lymphocyte-to-monocyte Ratio is an Independent Predictor of In-stent Restenosis After Percutaneous Coronary Intervention

**Kohei Ukita** , Osaka Rosai Hosp, Sakai, Japan

12:30 PM

Poster Professor

Khaled M Ziada, Lexington, KY

# Abstract Poster Session

## CA.APS.02 - iPS Cells

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 1066

NFkB is Necessary for Ips-derived Cardiomyocyte Maturation

**Conrad Hodgkinson** , Conrad Hodgkinson, DUKE UNIVERSITY, Durham, NC; Richard E Pratt, Duke Univ, Durham, NC; Victor Joseph Dzau, Natl Acad of Med, Washington, DC

12:30 PM

Board # 1067

IPS Cell-Deriverd Cardiac Tissue From Dilated Cardiomyopathy Patients With Lamin Variant Showed Impaired Systolic Function

**Koichiro Miura** , Katsuhisa Matsuura, Yu Yamasaki, Daisuke Sasaki, Yoshiyuki Furutani, Emiko Hayama, Tokyo Women's Medical Univ, Tokyo, Japan; Masamichi Ito, Tokyo Univ, Tokyo, Japan; Hiroyuki Morita, The Univ of Tokyo, Tokyo, Japan; Masashi Toyoda, Akihiro Umezawa, Natl Res Inst for Child Health and Development, Tokyo, Japan; Toshio Nakanishi, Nobuhisa Hagiwara, Tokyo Women's Medical Univ, Tokyo, Japan; Issei Komuro, Univ Tokyo, Tokyo, Japan; Tatsuya Shimizu, Tokyo Women's Medical Univ, Tokyo, Japan

12:30 PM

Board # 1068

Induced Pluripotent Stem Cell to Study Human Congenital Dilated Cardiomyopathy

**Young Wook Chun** , Univ of Maryland Baltimore, Baltimore, MD; Charles C Hong, Univ of Maryland Sch of Med, Nolensville, TN

12:30 PM

Board # 1070

Patient Derived Induced Pluripotent Stem Cells Based Drug Discovery Model for Leigh Syndrome

Glen Lester Sequiera, Niketa Sareen, Ejlal Abu-El-Rub, St. Boniface Gen Hosp Res Cen, Winnipeg, MB, Canada; Cheryl Rockman-Greenberg, Univ of Manitoba, Winnipeg, MB, Canada; **Sanjiv Dhingra** , St. Boniface Gen Hosp Res Cen, Winnipeg, MB, Canada

12:30 PM

Board # 1071

Ipsc-Derived Cardiomyocytes From Myotonic Dystrophy Type 1 Patients Reveal Sodium and Calcium Channels Dysfunction

**Hugo Poulin** , CERVO Res Ctr, Québec, QC, Canada; Aurélie Mercier, Valérie Pouliot, Mohammed Djemai, Laval Univ, Québec, QC, Canada; Jack Puymirat, Laval Univ, Quebec City, QC, Canada; Mohamed Boutjdir, VA NY Harbor Health Care System, Brooklyn, NY; Mohamed Chahine, Laval Univ, Quebec, QC, Canada

12:30 PM

Board # 1072

Induced Pluripotent Stem Cell Derived Cardiomyocyte Exosomes Preserve Myocardial Viability and Reduce Negative Remodeling in a Porcine Model of Ischemia Reperfusion

**Connor G Obrien** , Stanford Hosp, Stanford, CA; Yuko Tada, Michelle Santoso, Stanford Univ, Stanford, CA; Jennifer Lyons, Stanford Hosp, Stanford, CA; Jihye Jung, Stanford Sch of Med, Menlo Park, CA; Albert Jang, Cardiovascular Inst Stanford, Palo Alto, CA; Evgeniya Vaskova, Phillip C Yang, Stanford Univ, Stanford, CA

12:30 PM

Poster Professor

Sean M Wu, Stanford, CA

12:30 PM

Board # 1073

Substrate Stiffness Alters Human Induced Pluripotent Stem Cell-derived Cardiomyocyte Differentiation And Maturation

Yutao Xi, Texas Heart Inst, Houston, TX; Sheng-an Su, Zhejiang Univ Sch of Med, Hangzhou, China; Fernanda Mesquita, Camila Hochman-Mendez, Po-Feng Lee, Texas Heart Inst, Houston, TX; Shuiping So, Zhejiang Univ Sch of Med, Hangzhou, China; Jianhua Gu, Houston Methodist, Houston, TX; Jie Cheng, Luiz Sampaio, Texas Heart Inst, Houston, TX; Meixiang Xiang, Zhejang Univ Sch of Med, Hangzhou, China; **Doris A Taylor** , Texas Heart Inst, Houston, TX

12:30 PM

Board # 1074

Improvement of Relaxation Function is a Novel Index of Maturation in Human Induced Pluripotent Stem Cell-Derived Engineered Cardiomyocyte Tissues

**Hiroshi Goto** , The Univ of Tokyo, Tokyo, Japan; Katsuhisa Matsuura, Hidekazu Sekine, Tokyo Women's Medical Univ, Tokyo, Japan; Hyoe Komae, The Univ of Tokyo, Tokyo, Japan; Yu Yamasaki, Daisuke Sasaki, Tokyo Women's Medical Univ, Tokyo, Japan; Minoru Ono, The Univ of Tokyo, Tokyo, Japan; Tatsuya Shimizu, Tokyo Women's Medical Univ, Tokyo, Japan

# Abstract Poster Session

## MP.APS.03 - Kidney and Endocrine Interactions in Cardiovascular Disease

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 1157

Latent Transforming Growth Factor-Beta-Binding Protein 4 Deficiency Attenuated Renal Fibrosis After Myocardial Infarction

**Chi-Ting Su** , Renal Div, Internal Med, Natl Taiwan Univ of Hosp, Yun-Lin & Taipei Branch, Dou-Liu & Taipei, Taiwan; I-Hsien Fang, Inst of Clinical Med, Natl Cheng Kung Univ, Tainan, Taiwan; Yen-wen Liu, Div of Cardiology, Natl Cheng Kung Univ Hosp, Tainan, Taiwan; Tzu-Ming Jao, Graduate institute of Toxicology, Natl Taiwan Univ, Taipei, Taiwan; Zsolt Urban, Dept of Human Genetics, Univ of Pittsburgh, Pittsburgh, PA

12:30 PM

Board # 1158

Physiologic Crosstalk Between Circulating Renin-angiotensin and Natriuretic Peptide Systems in Humans: Implication for Cardiorenal Diseases

**Xiao Ma** , Seethalakshmi R Iyer, Valentina Cannone, Jeson Sangaralingham, John C Burnett, Mayo Clinic, Rochester, MN

12:30 PM

Board # 1159

Calmodulin-Dependent Protein Kinase II Activation Promotes Cardiac Structural Remolding and Kidney Mesangial Expansion in Streptozotocin-Induced Diabetic Mice

**Alexei V Mikhailov** , Jen-Jar Lin, Yixi Liu, Heng-Jie Cheng, Wake Forest Sch of Med, Winston-Salem, NC; David Herrington, Wake Forest Sch of Med, Winston Salem, NC; David Zhao, Che Ping Cheng, Wake Forest Sch of Med, Winston-Salem, NC

12:30 PM

Poster Professor

adriana Maria Hung Sr., Nashville, TN

12:30 PM

Board # 1160

Renovascular Hypertension Induces Myocardial Mitochondrial Damage, Contributing to Cardiac Injury and Dysfunction in Pigs With Metabolic Syndrome

**Arash Aghajani Nargesi** , Xiang-Yang Zhu, Lei Zhang, Mohamed C Farah, Amir Lerman, Lilach O Lerman, Alfonso Eirin, Mayo Clinic, Rochester, MN

12:30 PM

Board # 1161

Activation of JNK Signaling in Polymicrobial Sepsis Increases the Expression of B-Type Natriuretic Peptide, Which Promotes Septic Hypotension

**Matthew Hoffman** , Ioannis D. Kyriazis, Alexandra Dimitriou, Lewis Katz Sch of Med at Temple Univ, Philadelphia, PA; Santosh K. Mishra, North Carolina State Univ, Raleigh, NC; Walter J. Koch, Konstantinos Drosatos, Lewis Katz Sch of Med at Temple Univ, Philadelphia, PA

12:30 PM

Board # 1162

Prolonged Exposure to Elevated FGF23 Does Not Cause Left Ventricular Hypertrophy in Aged Mice

Denisse Leza Rincon, Baylor Coll of Med, Houston, TX; **Raphael Asher Wilson** , Neije Mukherjee-Roy, Yipin Wu, Priyatharshini Alphonse, UT Southwestern Medical Ctr, Dallas, TX; Nikhil Thatte, Boston Children's Hosp, Boston, MA; Surendranath R Veeram Reddy, Jyothsna Gattineni, UT Southwestern Medical Ctr, Dallas, TX

12:30 PM

Board # 1163

Vitamin D May be Associated With the Renal Effects of Angiotensin II Receptor Blocker in African Americans

**Li Chen** , Haidong Zhu, Ying Huang, Gregory Harshfield, Yanbin Dong, Augusta Univ, Augusta, GA

12:30 PM

Board # 1164

Paraoxonase-1 Regulation of Cardiac Inflammation and Fibrosis in Dahl Salt-Sensitive Model of Chronic Kidney Disease

**Prabhatchandra Dube** , Fatimah Khalaf, Armelle DeRiso, Chrysan Mohammed, Dhanushya Battepati, Andrew L Kleinhenz, Steven T Haller, Eric E Morgan, David J Kennedy, Univ of Toledo Health Science Campus, Toledo, OH

12:30 PM

Board # 1165

Centhaquine Attenuates Acute Kidney Injury Following Hemorrhagic Shock

Amaresh Ranjan, Midwestern Univ, Downers Grove, IL; Vivek Cherian, MedStar Union Memorial Hosp, Vienna, VA; Seema Briyal, Zhong Zhang, Megan Kotsko, Midwestern Univ, Downers Grove, IL; **Anil Gulati** , Pharmazz, Inc. and Midwestern Univ, Downers Grove, IL

12:30 PM

Board # 1166

Brown Adipose Tissue, a Novel Therapeutic Modality for Impaired Exercise Capacity

**Marko Oydanich** , Jie Zhang, New Jersey Medical Sch, Newark, NJ; Dorothy E Vatner, Stephen F Vatner, Rutgers Univ NJMS, Newark, NJ

12:30 PM

Board # 1167

Mesenchymal Stem Cells Evoke Enhanced Expression of Contraction-related Protein and Cytosolic Atp in Cardiomyocytes of Dilated Cardiomyopathy-like Hamster

**Daisuke Mori** , Shigeru Miyagawa, Takuji Kawamura, Hiroki Hata, Takayoshi Ueno, Koichi Toda, Kotoe Kawai, Hayato Kurata, Hiroyuki Nishida, Yoshiki Sawa, Osaka Univ, Suita, Japan

# Abstract Poster Session

## HF.APS.16 - Less Common Types of Cardiomyopathy

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2231

Myocardial Tissue Characterization by CMR in Active and Remission Stages of Light Chain Cardiac Amyloidosis

**Sarah AM Cuddy** , Michael Jerosch-Herold, Yiu Ming Khor, Alexandra Taylor, Marie Kijewski, Mi-Ae Park, Marcelo F Di Carli, Brigham and Women's Hosp, Boston, MA; Heather Landau, Memorial Sloan Kettering Cancer Ctr, New York, NY; Andrew J Yee, Massachusetts General Hosp, Boston, MA; Vaishali Sanchorawala, Boston Medical Ctr, Boston, MA; Frederick Ruberg, Boston Universiy Sch of Med, Boston, MA; Rodney H Falk, Raymond Kwong, Brigham and Women's Hosp, Boston, MA; Sharmila Dorbala, BRIGHAM and Womens, Boston, MA

12:30 PM

Board # 2232

Prevalence of Cardiac Amyloidosis in Patients Referred for Atrial Fibrillation Ablation by Cardiac MRI

**Christian Ngo** , Univ of Washington, Seattle, WA; Matthew Cham, Mount Sinai Medical Ctr, Edison, NJ; Nazem W Akoum, Richard Cheng, Univ Washington, Seattle, WA; Sofia Carolina Carolina Masri, Univ of Washington, Seattle, WA

12:30 PM

Board # 2233

Clinical and Image Characteristics of Patients With Arrhythmogenic Right Ventricular Cardiomyopathy With Fat and Fibrotic Invasion to Left Ventricular Myocardium Using Four-dimensional Cardiac Computed Tomography

**Nobusada Funabashi** , Yoshio Kobayashi, Chiba Univ, Chiba, Japan

12:30 PM

Board # 2234

Targeting F-fluorodeoxyglucose Positive Lymph Nodes for Biopsy on Positron Emission Tomography Imaging in Patients With Suspected Cardiac Sarcoidosis Has High Diagnostic Yield

**April M Shewmake** , Brian Mitchell, VCU Hosp System, Richmond, VA; Christopher Radchenko, Univ of Cincinnati Medical Ctr, Cincinnati, OH; Aamer A Syed, Thomas Iden, Huzaefah Syed, VCU Hosp System, Richmond, VA; Kenneth A Ellenbogen, Virginia Commonwealth Univ Health System, Richmond, VA; Ray W Shepherd, VCU Hosp System, Richmond, VA; Jordana Kron, Virginia Commonwealth Univ, Richmond, VA

12:30 PM

Board # 2235

Nonischemic Left Ventricular Aneurysms With Undetermined Etiology Are Frequently Due to Cardiac Sarcoidosis

**Steve Guo** , Sandhya Murthy, Omar Saeed, Patricia Chavez, Snehal R Patel, Montefiore Medical Ctr, Bronx, NY; Sasha Vukelic, Montefiore Medical Centar AECOM, Bronx, NY; Jooyoung Shin, Montefiore, Bronx, NY; Ulrich P Jorde, Montefiore / Einstein, Bronx, NY; Daniel B Sims, Montefiore Medical Ctr, New York, NY

12:30 PM

Board # 2236

The Role of Hyperhf Score to Predict Heart Failure and Related Cerebrovascular Events

Hyun-Bin Park, Jae-Man Lee, Ji-Hun Song, Keimyung Univ Coll of Med, Daegu, Korea, Republic of; Jaewon Oh, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Jong-Chan Youn, Hallym Univ Coll of Med, Hwaseong, Korea, Republic of; Hyungseop Kim, Keimyung Univ Coll of Med, Daegu, Korea, Republic of; Geu-Ru Hong, Seok-min Kang, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; **In-Cheol Kim** , Keimyung Univ Coll of Med, Daegu, Korea, Republic of

12:30 PM

Board # 2237

Tetrahydrobiopterin is a Novel CamKK2 Activator Which Rescues Late-stage Diabetic Cardiomyopathy in Rodent Model

**Jung Eun Jang** , Inje Univ Coll of Med, Busan, Korea, Republic of; Hyoung Kyu Kim, Inje Univ, Busan, Korea, Republic of; Jin Han, Inje Univ Coll of Med, Busan, Korea, Republic of

12:30 PM

Board # 2238

Coronary Jeopardy Score Predicts Ischemic Etiology in Patients With Left Ventricular Systolic Dysfunction

**Matthew James Ryan** , Natalia Briceno, Adriana Villa, Haseeb Rahman, Bhavik Modi, Amedeo Chiribiri, Divaka Perera, King's Coll London, London, United Kingdom

12:30 PM

Board # 2239

Diverse Cardiac Phenotype of Becker Muscular Dystrophy: Underrecognized Preclinical Cardiomyopathy in Pediatrics

**Takeshi Tsuda** , Alfred I Dupont Hosp for Children, Wilmington, DE; Kristi Fitzgerald, Alfred I Dupont Hosp for Children, Wilmington, NJ

12:30 PM

Board # 2240

Echocardiographic Characteristics of Peripartum Cardiomyopathy Compared to Preeclampsia

**Bassman Tappuni** , Good Samaritan Hosp/Trihealth, Cincinnati, OH; Ali AlKhayru, Belal Kaseer, Freidoon Ghazi, John Wilson, William Thomas Schnettler, Kathleen L Smith, Jenni Steinbrunner, Kamal Shemisa, Good Samaritan Hosp, Cincinnati, OH

# Abstract Poster Session

## AT.APS.11 - Lipoprotein and Lipid Function in Atherogenesis

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Poster Professor

Rebecca Haeusler, New York, NY

12:30 PM

Board # 1014

Statin Inhibits Oxidized Phospholipid Povpc- Induced Endothelial to Mesenchymal Transition

**Zhijun Ou** , Yan Li, Jing Chen, Da-Sheng Ning, Zhi-Wei Mo, Yue-Ming Peng, Jingsong Ou, No1 Hosp of Sun Yat-sen Univ., Guangzhou, China

12:30 PM

Board # 1015

Reduced Lipoprotein(a) Associated With the Apolipoprotein E2 Genotype Confers Cardiovascular Protection in Familial Hypercholesterolemia

**Valentin Blanchard** , Gilles Lambert, Lab Inserm UMR DéTROI, Sainte Clotilde, Réunion

12:30 PM

Board # 1016

Differences in Lipoprotein Particle Number Evaluation Between Gel Permeation-High Performance Chromatography and Nuclear Magnetic Resonance: Analysis in Dyslipidemic Patients Treated With a Selective Peroxisome Prolifetator-Activated Receptor α Modulator, Pemafibrate

**Shizuya Yamashita** , Rinku General Medical Ctr, Izumisano City/Osaka Prefecture, Japan; Mitsuyo Okazaki, Tokyo Medical and Dental Univ, Bunkyo-ku, Tokyo, Japan; Takeshi Okada, Osaka Univ Graduate Sch of Med, Suita City/Osaka Prefecture, Japan; Daisaku Masuda, Rinku General Medical Ctr, Izumisano City/Osaka Prefecture, Japan; Hidenori Arai, Natl Ctr for Geriatrics and Gerontology, Obu City/Aichi Prefecture, Japan; Koutaro Yokote, Chiba Univ Graduate Sch of Med, Chiba City/Chiba Prefecture, Japan; Eiichi Araki, Faculty of Life Sciences, Kumamoto Univ, Kumamoto City/Kumamoto Prefecture, Japan; Shun Ishibashi, Jichi Medical Univ, Shimotsuke City/Tochigi Prefecture, Japan

12:30 PM

Board # 1017

Hyperuricemia is an Independent Risk Factor for Cardiovascular Disease; A Sub-Analysis for REAL-CAD Study

**Masanari Kuwabara** , Toranomon Hosp, Tokyo, Japan; Tetsuji Kaneko, Teikyo Univ, Tokyo, Japan; Ikki Komatsu, Sunnybrook Health Science Ctr, Toronto, ON, Canada; Nobuyuki Komiyama, St. Luke's Intl Hosp, Tokyo, Japan; Yasuo Ohashi, Chuo Univ, Tokyo, Japan; Ryozo Nagai, Jichi Medical Univ, Shimotuke Tochigi, Japan; Satoshi Iimuro, Intl Univ of Health and Welfare, Tokyo, Japan

12:30 PM

Board # 1018

Advanced Lipid Testing Uncovers Residual Coronary Heart Disease Risk

**Eveline Oestreicher Stock** , Univ California San Francisco, San Francisco, CA; Ernst J Schaefer, Boston Heart Diagnostics, Boston, MA; Creasy Townsend Kate, Univ California San Francisco, San Francisco, CA; Lihong He, Margaret R Diffenderfer, Boston Heart Diagnostics, Framingham, MA; Bela F Asztalos, Tufts Univ, Boston, MA; John P Kane, Univ California San Fran, San Francisco, CA

12:30 PM

Board # 1019

Impact of Haptoglobin Genotype and Diabetes Status on Anacetrapib-Mediated Increase in Cholesterol Efflux Capacity

**Jaskeerat Gulati** , Mark Metzinger, Suzanne Saldanha, Ayea El-Ghazali, Sneha Deodhar, Aseruchi Chindah, UT Southwestern, Dallas, TX; Colby R. Ayers, UT Southwestern Medical Ctr, Dallas, TX; Anand Rohatgi, UT Southwestern, Dallas, TX

12:30 PM

Board # 1020

Correlation of Measures of Cardiovascular Risk to Novel Proteomic Measure of HDL Function

**Marc S Penn** , Summa Health Heart and Vascular Inst, Akron, OH; Nicolas Chronos, Cardiology Care Clinic, Eatonton, GA; David DeSantis, Cleveland Heart Lab, Cleveland, OH; Timothy Collier, Cleveland Heart lab, Cleveland, OH; Michael J McPhaul, Quest Diagnostics, Inc., San Juan Capistrano, CA

12:30 PM

Board # 1021

Adiponectin and Apolipoprotein A-1 Modulate Efficiently Cellular Cholesterol Removal During High-Density Lipoprotein Biogenesis

**Anouar Hafiane** , Stella Styliani Daskalopoulou, McGill Univ, Montreal, QC, Canada

12:30 PM

Board # 1022

C-terminal Truncation of Apolipoprotein A1 Glutamate Residue 243 is Associated With Coronary Artery Disease and Chronic Kidney Disease

**Zachary T Wilson** , Univ of Arizona Coll of Med – Phoenix, Phoenix, AZ; Ghazwan Elias, Univ of Texas Health San Antonio, San Antonio, AZ; Dan Krause, Linda Pham, Maricopa Integrated Health System, Phoenix, AZ; Paul Kang, Univ of Arizona Coll of Med – Phoenix, Phoenix, AZ; Joshua Jeffs, Nilojan Jehanathan, Chad Borges, ASU Biodesign Inst, Tempe, AZ; Christian Breburda, Heart & Vascular Ctr of Arizona, Phoenix, AZ

# Abstract Poster Session

## NR.APS.02 - Living with CVD: Promoting Self-Management

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4226

Health Related Quality of Life Mediates the Relationship Between Medication Adherence and Cardiac Event-free Survival in Patients With Heart Failure

**Jia Rong Wu** , Unc-Chapel Hill, Chapel Hill, NC; Debra Moser, Univ of Kentucky, Lexington, KY

12:30 PM

Board # 4227

Influence of Depression on Self-Care Behaviors in Older Adults With Multiple Chronic Conditions: A Multivariate Analysis

**Paolo Lovino** , Univ of Tor Vergata, Rome, Italy; Ercole Vellone, Maddalena De Maria, Univ of Rome Tor Vergata, Rome, Italy; Silvia Lorini, Univ of Tor Vergata, Rome, Italy; Davide Ausili, Univ of Bicocca, Milano, Italy; Maria Matarese, Campus Biomedico, Rome, Italy; Barbara J Riegel, Univ Pennsylvania, Philadelphia, PA

12:30 PM

Board # 4228

Co-Morbid HF-DM Disease Sequence Effects on Self-Care and Symptoms Management

**Melinda Higgins** , Sandra B Dunbar, Carolyn M Reilly, Emory Univ, Atlanta, GA; Rebecca Gary, Emory Univ, Commerce, GA; Brittany Butts, Emory Univ, Atlanta, GA; Javed Butler, Univ of Mississippi, Jackson, MS

12:30 PM

Board # 4230

Psychosocial Factors Mediate the Association of Adverse Life Experiences and BMI in African American Women

**Billy A Caceres** , Columbia Univ, New York, NY; Veronica Barcelona De Mendoza, Yale Univ Sch of Nursing, Orange, CT; Cindy Crusto, Yale Univ, New Haven, CT; Jacquelyn Y Taylor, New York Univ, New York, NY

12:30 PM

Board # 4231

Postmenopausal Breast Cancer Survivors Are Susceptible To Sub-optimal Care For High Blood Pressure

**Na-Jin Park** , Alicia Bagiatis, Univ of Pittsburgh, Pittsburgh, PA

12:30 PM

Board # 4232

The Feasibility of a Combined Lifestyle Physical Activity and Cognitive Training Intervention to Prevent Memory Loss in Older Women With Cardiovascular Disease

**Shannon Halloway** , Joellen Wilbur, Michael E. Schoeny, Rush Univ, Chicago, IL; Lynne T Braun, Rush Univ Medical Ctr, Chicago, IL; Annabelle Santos Volgman, Rush Univ, Chicago, IL

12:30 PM

Board # 4233

Awareness of Cardiovascular Risk and Practice of Health Behaviors Among Cancer Survivors

**Kyungeh An** , Masey Ross, Virginia Commonwealth Univ, Richmond, VA; Tae shik Park, Virginia Commonwealth Univ HS, Richmond, VA; Cheongtag Kim, Seoul Natl Univ, Seoul, Korea, Republic of

12:30 PM

Board # 4234

Sexual Activity After Heart Transplant: The Truth in Intimacy

**Gina Jamero** , Angela Velleca, Kristine Norland, Michelle Curry, Michelle M Kittleson, SMIDT Heart Inst Cedars-Sinai, Los Angeles, CA; Jignesh K Patel, SMIDT Heart Inst Cedars-Sinai, Beverly Hills, CA; Ryan Levine, Elizabeth Passano, Jon A Kobashigawa, SMIDT Heart Inst Cedars-Sinai, Los Angeles, CA

12:30 PM

Board # 4235

Avoiding The D Words: Death And Advanced Directives In A Left Ventricular Assist Device Population

**Jessica L Harman Thompson** , Debra K Moser, Univ of Kentucky, Lexington, KY; Devan Elizabeth Costelle, Univ of Kentucky, Goshen, KY

12:30 PM

Poster Professor

Jo-ann Eastwood, Manhattan Bch, CA

12:30 PM

Board # 4236

Statin-Associated Immune-Mediated Necrotizing Myopathy: A Mayo Clinic Experience

**Absar Tahir** , James D. Triplett, Margherita Milone, Stephen Kopecky, Mayo Clinic, Rochester, MN

12:30 PM

Board # 4237

Diagnoses of Depression and Fatigue Are Mutually Associated in Patients With Heart Failure?

**Seongkum Heo** , Univ Arkansas for Med Sciences, Little Rock, AR; Jean C McSweeney, Univ of Ark. for Medical Sci. CON, Little Rock, AR; Pao-Feng Tsai, Songthip Ounpraseuth, Univ Arkansas for Med Sciences, Little Rock, AR; JinShil Kim, Gachon Univ, Incheon, Korea, Republic of

12:30 PM

Board # 4238

Do Changes in Modifiable Factors Actually Lead to Changes in Quality of Life at 3 Months in Patients With Heart Failure?

**Seongkum Heo** , Univ Arkansas for Med Services, Little Rock, AR; JinShil Kim, Gachon Univ, Incheon, Korea, Republic of; Mi-Seung Shin, Albert Youngwoo Jang, Gachon Univ Gil Medical Ctr, Incheon, Korea, Republic of

12:30 PM

Board # 4239

Nurse-Led Positive Psychology Intervention is Feasible in Patients With Heart Failure

**Martha J Biddle** , Erin Taylor 40536, Madeline Rukavina 40536, Denise Sparks 40536, Gretchen L Wells 40536, Univ of Kentucky, Lexington, KY

12:30 PM

Board # 4240

Reflections on Health Behaviors and Suggestions for Future Health Promotion Programs From African American Women

**Se Hee Min** , Robin Whittemore, Holly Kennedy, Soohyun Nam, Yale Univ, Orange, CT

# Abstract Poster Session

## HF.APS.13 - LVAD: Complications and Outcomes

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2196

Long-Term Outcomes With the Use of Mechanical Circulatory Support in Patients With Severe Peripartum Cardiopulmonary Failure

**Federico Sertic** , Hansie Mathelier, Jennifer Lewey, Univ of Pennsylvania, Philadelphia, PA; Zoltan Arany, Univ Pennsylvania, Philadelphia, PA; Samip Sheth, Univ of Pennsylvania, Philadelphia, PA; Dennis M McNamara, UPMC, Venetia, PA; Nimesh D Desai, Michael Andrew Acker, Lisa Levine, Christian Bermudez, Univ of Pennsylvania, Philadelphia, PA; Uri Elkayam, Lac Usc Medical Ctr, Los Angeles, CA; J Eduardo Rame, Univ of Pennsylvania, Philadelphia, PA

12:30 PM

Board # 2197

The Penn-Columbia Risks Score Outperforms Other Previously Validated Pre-Operative Risk Scores For Predicting Long-term Outcomes In Lvad Patients

**Ramsey Wehbe** , Northwestern Med, Chicago, IL; Jane Wilcox, Kambiz Ghafourian, Ike Okwuosa, Northwestern Univ, Chicago, IL; Faraz S Ahmad, Northwestern Univ Sch Med, Chicago, IL; Allen S. Anderson, Northwestern Med, Chicago, IL; Clyde W Yancy Jr., Northwestern Univ, Chicago, IL; Duc Pham, Northwestern Med, Chicago, IL; Jonathan Rich, Northwestern Univ, Skokie, IL; Esther Vorovich, Northwestern Univ, Skokie, IL, Wilmette, IL

12:30 PM

Board # 2198

Breaking the Barriers in Heart Failure Care: Understanding Patient Referral Practices to Advanced Heart Failure Centers

**Jared J Herr** , California Pacific Medical Ctr, San Francisco, CA; Ashwin Ravichandran, St. Vincent Heart Ctr, Indianapolis, IN; Christopher Chien, Univeristy of North Carolina, Raleigh, NC; Stephen J Forest, Montefiore Medical Ctr, Albert Einstein Coll of Med, Bronx, NY; Benjamin D'Souza, Penn Presbetryian Medical Ctr, Perelman Sch of Med at the Univ of Pennsylvania, Philadelphia, PA

12:30 PM

Board # 2199

Association of Relative Ambient Temperature and LVAD-Associated Infection Rate

**Dawn Pasquarello** , Johana Fajardo, Kevin Welch, Vijay Chand, Leslie Gilbert, Lonnie Ennis, Clifford A Beach, MUSC, Charleston, SC; Lucian Lozonschi, Univ Wisconsin, Madison, WI; Thomas Disalvo, MUSC, Charleston, SC; Ryan J Tedford, Medical Univ South Carolina, Charleston, SC; Brian A Houston, MUSC, Charleston, SC

12:30 PM

Board # 2200

Predictors of Severe Right Ventricular Failure After Left Ventricular Assist Device

**Yuko Soyama** , Washington Univ in St. Louis, Saint Louis, MO; Maria Karmpalioti, Washington Univeristy in St. Louis, st. louis, MO; Peter Huntjens, Washington Univ in St. Louis, St Louis, MO; David Raymer, Shane LaRue, Akinobu Itoh, Washington Univ in St. Louis, Saint Louis, MO; Justin M Vader, Washington Univ, Saint Louis, MO; John Gorcsan III, Washington Univ at St. Louis, Saint Louis, MO

12:30 PM

Board # 2201

Hyponatremia is Associated With Higher Readmission Rates in Patients With Left Ventricular Assist Devices

**Anthony J Kanelidis** , Teruhiko Imamura, Ben Yang, Tamari Miller, Murtaza Bharmal, Gene H Kim, Gabriel T Sayer, Nir Uriel, Univ of Chicago, Chicago, IL

12:30 PM

Board # 2202

Heart Transplantation and Not Left Ventricle Assist Device Therapy Restores Circadian Variability of Pulse Pressure Amplification in Heart Failure Patients

**Francesco Castagna** , Giulio M Mondellini, Alberto Pinsino, Columbia Univ Medical Ctr, New York, NY; Barry J McDonnell, Cardiff Metropolitan Univ, Cardiff, United Kingdom; Eric Stohr, Antonia Gaudig, Amrin Amlani, Joseph Nwokocha, Columbia Univ Medical Ctr, New York, NY; Carmel M McEniery, Univ of Cambridge, Cambridge, United Kingdom; Koji Takeda, Hiroo Takayama, Yoshifumi Naka, Melana Yuzefpolskaya, Columbia Univ Medical Ctr, New York, NY; Gianfranco Parati, Istituto Auxologico Italiano, IRCCS, Ospedale San Luca & Dept of Med and Surgery, Univ of Milano-Bicocca, Milan, Italy; John Cockcroft, Cardiff Metropolitan Univ, Cardiff, United Kingdom; Paolo C Colombo, Columbia Univ Medical Ctr, New York, NY

12:30 PM

Board # 2203

Impact of Time off Anticoagulation in Patients With Continuous Flow Left Ventricular Assist Devices

**Ashley Patel** , Christian Inchaustegui, Baylor Coll of Med, Houston, TX; Harveen Lamba, Texas Heart Inst, Houston, TX; Andrew Brown, Kevin Ting, Justin Arunthamakun, Baylor Coll of Med, Houston, TX; Joggy George, Andrew Civitello, Texas Heart Inst, Houston, TX

12:30 PM

Board # 2204

Measuring Strength and Physical Activity in Patients With Advanced Systolic Heart Failure With Left Ventricular Assist Devices

Alexandra Coston, Joronia Chery, Rachel Porth, Matthew Lawrence, **Amanda R Vest** , Tufts Medical Ctr, Boston, MA

12:30 PM

Board # 2205

Effect of Anesthesia on Cardiac Hemodynamics in Patients Undergoing Durable Left Ventricular Assist Device Implantation (EACH LVAD Study): Substudy of the Echocardiographic Parameters

**Bénédicte Lefebvre** , Univ of Pennsylvania, Philadelphia, PA; Thomas C Hanff, Univ of Pennsylvania, Haddonfield, NJ; Prakash A Patel, Kristy Kurcik, Pavan Atluri, christian bermudez, Michael Andrew Acker, J Eduardo Rame, Edo Birati, Joyce Wald, Univ of Pennsylvania, Philadelphia, PA

12:30 PM

Poster Professor

Amanda R Vest, Boston, MA

# Abstract Poster Session

## CH.APS.12 - Man vs. Machine: Tech in Kids

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4031

Can Machine Learning Predict Hospitalization From Sparse Interstage Home Monitoring Data of Single Ventricle Infants?

**Anirban Banerjee** , Fuchiang R. Tsui, Jorge J Guerra Marin, Victor Ruiz, Shobha Natarajan, Anita L Szwast, Alyson Stagg, Therese M Giglia, Children's Hosp of Philadelphia, Philadelphia, PA

12:30 PM

Board # 4032

Comparison and Regression Tree Analysis Predicts Pediatric Heart Transplant Patients With Prolonged Length of Stay

**Chesney D Castleberry** , Micheal Wallendorf, Jingxia Lu, Washington Univ in St. Louis, Saint Louis, MO; Janet N Scheel, St Louis Childrens, Saint Louis, MO; Pirooz Eghtesady, Washington Univ in St. Louis, St Louis, MO; Charles E Canter, Washington Univ Sch Med, Saint Louis, MO

12:30 PM

Board # 4033

Predicting Total Cardiac Volume for Donor-Recipient Size Matching: Case for an Image-Based Deep Learning Approach

**Nicholas Szugye** , Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; Nicholas Ollberding, CCHMC, Cincinnati, OH; Philip Khoury, David Morales, Farhan Zafar, Cincinnati Children's Hosp, Cincinnati, OH; Ryan Allen Moore, CCHMC, Cincinnati, OH

12:30 PM

Board # 4034

Screening for Intracranial Aneurysms in Coarctation of the Aorta: A Decision and Cost-effectiveness Analysis

**Sarah S. Pickard** , Ashwin Prakash, Jane W Newburger, Boston Children's Hosp, Boston, MA; Adel M. Malek, John B Wong, Tufts Univ Sch of Med, Boston, MA

12:30 PM

Board # 4035

A Machine Learning Approach to Identify Risk Factors for Post-Operative Complications After Tetralogy of Fallot Repair

Jennifer A Faerber, Jing Huang, Xuemei Zhang, Lihai Song, Christopher Mascio, Chitra Ravishankar, Francis X McGowan, Michael O'Byrne, Elizabeth Goldmuntz, Childrens Hosp of Philadelphia, Philadelphia, PA; **Laura M Mercer-Rosa** , Childrens Hosp Philadelphia, Philadelphia, PA

12:30 PM

Board # 4036

Simulated Transcatheter Device Closure of Atrial and Ventricular Septal Defects Using 3D Echocardiogram Derived Models in Virtual Reality

**Hannah Nam** , Christian Herz, Adriana Posada, Children's Hosp of Philadelphia, Philadelphia, PA; Andras Lasso, Queen's Univ, Kingston, ON, Canada; Simon Drouin, Brigham and Women's Hosp, Boston, MA; Brian Morray, Seattle Childrens Hosp, Seattle, WA; Michael O'Byrne, Children's Hosp of Philadelphia, Philadelphia, PA; Beatriz Paniagua, Kitware Inc, Carrboro, NC; Denise Joffe, Seatle Children's Hosp, Seattle, WA; G. Burkhard Mackensen, Univ of Washington, Seattle, WA; Lindsay S Rogers, Children's Hosp of Philadelphia, Philadelphia, PA; Gabor Fichtinger, Queen's Univ, Kingston, ON; Matthew Jolley, Children's Hosp of Philadelphia, Philadelphia, PA

12:30 PM

Board # 4037

Modeling Postoperative Intensive Care Length of Stay to Improve Resource Management at Congenital Heart Centers

**Peta MA Alexander** , Kimberlee Gauvreau, Boston Children's Hosp, Boston, MA; Michael G Gaies, Univ of Michigan, Ann Arbor, MI; Aaron Gabriel DeWitt, Children's Hosp of Philadelphia, Philadelphia, PA; Shirley Ge, Boston Children's Hosp, Boston, MA; Nancy Ghanayem, Childrens Hosp of Wisconsin, Houston, TX; Javier J Lasa, Texas Children's Hosp, Houston, TX; Alaina Kipps, Lucile Packard Children's Hosp, Palo Alto, CA; Kshitij Mistry, Boston Children's Hosp, Boston, MA; Steven M Schwartz, Hosp for Sick Children, Toronto, ON, Canada; Andrew Shin, Stanford Children's Health, Menlo Park, CA; Ravi R Thiagarajan, Childrens Hosp Boston, Boston, MA; Lisa Bergersen, Boston Children's Hosp, Boston, MA

12:30 PM

Board # 4038

Quantitative Analysis of Chest X-Ray Using Deep Learning to Predict Pulmonary to Systemic Flow Ratio in Patients With Congenital Heart Disease

**Shuhei Toba** , Mie Univ Graduate Sch of Med, Tsu, Mie, Japan; Yoshihide Mitani, Mie Univ Graduate Sch of Med, Tsu City, Japan; Hiroyuki Ohashi, Mie Univ Graduate Sch of Med, Tsu, Japan; Hirofumi Sawada, Mie Unviersity Graduate Sch of Med, Mie, Japan; Noriko Yodoya, Mie Univ Graduate Sch of Med, Tsu, Japan; Hidetoshi Hayakawa, Masahiro Hirayama, Ayano Futsuki, Naoki Yamamoto, Hisato Ito, Takeshi Konuma, Mie Univ Graduate Sch of Med, Tsu, Mie, Japan; Hideto Shimpo, Mie Univ Graduate Sch of Med, Tsu, Japan; Motoshi Takao, Mie Univ Graduate Sch of Med, Tsu, Mie, Japan

12:30 PM

Board # 4039

Hemodynamic Contributions of Computer Aided Designs and Surgeon's Unconstrained Modelling to the Fontan Operation: A Computational Fluid Dynamic Simulation Study

**Yue-hin Loke** , Children's Natl Health Systems, Washington DC, DC; Byeol Kim, Univ of Maryland, College Park, MD; Paige Mass, Childrens Natl Medical Ctr, Washington, DC; Justin Opfermann, Children's Natl Medical Ctr, Washington, DC; Axel Krieger, Univ of Maryland, College Park, MD; Narutoshi Hibino, Univ of Chicago Advocate Children's Hosp, Chicago, IL; Laura Olivieri, Natl Insts of Health, Bethesda, MD

12:30 PM

Board # 4040

Direct-to Consumer Cardiology Telemedicine: A Single Large Academic Pediatric Center Experience

**Aaron Phillips** , Children's Natl Medical Ctr, Washington, DC; Craig A Sable, Children's Natl Health System/ George Washington Univ, Washington, DC; Christina Waggaman, Children's Natl Medical Ctr, Washington, DC; Ashraf S Harahsheh, Children's Natl Health System/ George Washington Univ, Washington, DC

12:30 PM

Poster Professor

Animesh A Tandon, Dallas, TX

# Abstract Poster Session

## EA.APS.12 - Molecular Targets for Arrhythmias

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2046

Patient-derived Induced Pluripotent Stem Cell Model of Drug-induced QT Prolongation Implicates the PI3K Pathway

**Andrew M Glazer** , Andrew T Hale, Vanderbilt Medical Ctr, Nashville, TN; Yuko Wada, Vanderbilt Univ Medical Cente, Nashville, TN; Joe-Elie Salem, Sorbonne Univ, INSERM, Paris, France; Laura Short, VUMC, Nashville, TN; Marcia Blair, Vanderbilt Univ, Nashville, TN; Tao Yang, Vanderbilt Univ Medical Ctr, Nashville, TN; Lynn Hall, Vanderbilt Univ Medical Ctr., Nashvivlle, TN; Teresa L Strickland, Kevin R Bersell, Ayesha Muhammad, Vanderbilt Medical Ctr, Nashville, TN; Shan Parikh, Vanderbilt Univ Medical Ctr, Nashville, TN; Joshua Charles Denny, Vanderbilt Univ, Nashville, TN; Bjorn C Knollmann, Dan M Roden, Vanderbilt Medical Ctr, Nashville, TN

12:30 PM

Board # 2047

Pharmacological Modulation of Mitochondria Ca2+ Exerts Divergent Effects on Arrhythmogenic Calcium Waves in Ca2+-dependent and Metabolic Cardiac Disease

Brian Tow, Anna-Beth Loper, Collinsville, MS; Bjorn C Knollmann, Vanderbilt Univ, Nashville, TN; Sandor Gyorke, Ohio State Univ, Columbus, OH; **Bin Liu** , Mississippi State Univ, Starkville, MS

12:30 PM

Board # 2048

Functional Evidence Of Two Anatomically Distinct Right Atrial Pacemakers In The Rodent Heart

**Jaclyn Brennan** , Igor Efimov, The George Washington Univ, Washington, DC

12:30 PM

Board # 2049

The Difference of Calmodulin-Ryanodine Receptor Affinity Between N-terminal, Central and C-terminal RyR2-CPVT Knock-in Mice

**Hitoshi Uchinoumi** , Yamaguchi Univ, Ube, Japan; Xiaoqiong Dong, Ivanita Stefanon, Mena Said, Rogerio Faustino, Univ of California Davis, Davis, CA; Razvan L Cornea, Univ of Minnesota, Minneapolis, MN; Xander H.t. Wehrens, Baylor Coll of Med, Houston, TX; Takeshi Yamamoto, Masafumi Yano, Yamaguchi Univ, Ube, Japan; Donald M Bers, Univ of California Davis, Davis, CA

12:30 PM

Board # 2050

**Chronic Beta3-Adrenergic Receptor Blockade Restores Beta-Adrenergic Positive Modulation on Cardiomyocyte L-Type Ca** 2+ **Current in Rats With Advanced Heart Failure**

**Che Ping Cheng** , Peng Zhou, Atsushi Morimoto, Xiaowei Zhang, David Zhao, David Herrington, Dalane Kitzman, Heng-Jie Cheng, Wake Forest Sch of Med, Winston-Salem, NC

12:30 PM

Board # 2051

**Neuronal Na** + **Channel Inhibitor Riluzole Prevents Atrial Fibrillation in Humans**

Mark A Munger, Univ Utah, Salt Lake City, UT; Jessica Mandroli, St. Agostino Estense Hosp, Azienda Ospedaliero Univria di Modena, Modena, Italy; Kibum Kim, Univ of Utah, SLC, UT; Joseph Biskupiak, Univ of Utah, Salt Lake City, UT; Rengasayee Veeraraghavan, The Ohio State Univ, Roanoke, VA; Sandor Gyorke, **Przemyslaw Radwanski** , Ohio State Univ, Columbus, OH

12:30 PM

Board # 2052

Diastolic Dysfunction and High Susceptibility to Arrhythmias in a Mouse Model of Restrictive Cardiomyopathy

**Emmanuel M. Camors** , Alyson H Roth, UTHSC-Le Bonheur Hosp, Memphis, TN; Enkhsaikhan Purevjav, Univ of Tennessee Health Sci, Memphis, TN; Evangelia Litsa Kranias, Uni of Cincinnati Coll Med, Cincinnati, OH; Jeffrey A Towbin, Le Bonheur Childrens Hosp, Memphis, TN

12:30 PM

Board # 2053

The Crystal Structure of a Cardiac Calsequestrin Filament Reveals an Atomic Mechanism of Calsequestrin-associated Catecholaminergic Polymorphic Ventricular Tachycardia

**Erron W Titus** , Frederick H Deiter, Chenxu Shi, Julianne Wojciak, Univ of California, San Francisco, San Francisco, CA; Melvin Mayer Scheinman, Natalia Jura, UCSF, San Francisco, CA; Rahul C Deo, Brigham and Women's Hosp, San Francisco, CA

12:30 PM

Board # 2054

Mitochondrial Oxidative Stress From Increased NADPH Oxidase 4 Levels Induces Paroxysmal Atrial Fibrillation

**Roberto Ramos-Mondragon** , Aleksandr E Vendrov, Andrey Lozhkin, Justus Mb Anumonwo, Lori L Isom, Nageswara R Madamanchi, Marschall S Runge, Univ of Michigan, Ann Arbor, MI

12:30 PM

Poster Professor

Jidong Fu, Cleveland, OH

12:30 PM

Board # 2055

**Multiwell Microelectrode Array Technology for Multimodal Characterization of Cardiomyocyte Function** in vitro

**Daniel Millard** , Heather Hayes, Anthony Nicolini, Colin Arrowood, Mike Clements, James Ross, Axion BioSystems, Atlanta, GA

12:30 PM

Board # 2056

Assessment of Molecular Mechanisms of Sex Dependence of Drug-induced Arrhythmias

Kevin R. DeMarco, Pei-Chi Yang, Kazuharu Furutani, Brandon M. Brown, John R. D. Dawson, Univ of California, Davis, Davis, CA; Junko Kurokawa, Univ of Shizuoka, Shizuoka, Japan; Sergei Y. Noskov, Univ of Calgary, Calgary, AB, Canada; Jon T. Sack, Vladimir Yarov-Yarovoy, Heike Wulff, Colleen E. Clancy, **Igor Vorobyov** , Univ of California, Davis, Davis, CA

# Abstract Poster Session

## SA.APS.08 - Myocardial Protection, Intraoperative Management and Critical Care I

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Poster Professor

J Daniel D Muehlschlegel, Boston, MA

12:30 PM

Board # 4283

The Effect of Influenza Vaccination on the Systemic Inflammatory Response and Myocardial Protection in Patients Undergoing Cardiac Surgery: A Randomized Controlled Trial

**Fady Ebrahim** , John Mireau, Kevin Saroka, Janet McElhaney, Rony Atoui, Health Sciences North, Sudbury, ON, Canada

12:30 PM

Board # 4284

Role of LncRNA MALAT-1 and MicroRNA-199 in Rapamycin Induced Cardioprotection Against Reperfusion Injury in Diabetic Rabbits

Arun Samidurai, Ramzi A Ockaili, Chad Cain, Sean K Roh, Donatas Kraskauskas, Fadi N Salloum, Rakesh C Kukreja, **Anindita Das** , Virginia Commonwealth Univ, Richmond, VA

12:30 PM

Board # 4285

Role of Transient Receptor Potential Ankyrin-1 in Isoflurane-Induced Myocardial Depression in Mice

**Detlef Obal** , Stanford Univ, Palo Alto, CA; Kartik Katragadda, Ganapathy Jagatheesan, Sujith Dassanayaka, Kenneth Brittian, Daniel Riggs, Daniel J Conklin, Univ of Louisville, Louisville, KY

12:30 PM

Board # 4287

Survival Effect of Beta-Blockers in Patients With Asymptomatic Perioperative Troponin Elevation

**Sandra Shenouda** , Abhishek Dutta, Hanumanthu Jogu, Jonathan Brock, Imtiaz Ahmad, Parag Anilkumar Chevli, Padageshwar Sunkara, Tareq Islam, Chi-Cheng Huang, Wake Forest Baptist Health, Winston-Salem, NC

12:30 PM

Board # 4288

A Suggested Redosing Interval of Del Nido Cardioplegia Solution in Adult Cardiac Surgery: A Propensity-matched Study

**Takeyoshi Ota** , The Univ of Chicago, Chicago, IL; Hiroto Kitahara, MedStar Washington Hosp center, Washington, DC., WA; Hidefumi Nishida, The Univ of Chicago, Chicago, IL; Valluvan Jeevanandam, Univ Chicago Medical Ctr, Chicago, IL; Takeyoshi Ota, The Univ of Chicago, Chicago, IL

12:30 PM

Board # 4289

Circulating Mitochondrial DNA Released by Ischemic Myocaridium Exacerbate Reperfusion Injury by Activating Inflammatory Response via HMGB1-RAGE Pathway

**Mingbiao Li** , Shihi Chang, Degang Liang, Tianjin Medical Univ General Hosp, Tianjin, China; Zequang Yang, Univ of Virginia, Charlottesville, VA; Yikui Tian, Tianjin Medical Univ General Hosp, Tianjin, China

12:30 PM

Board # 4290

Identification of SERCA2 as a Novel Effector and Therapeutic Target in Acute Post-Operative Right Ventricular Dysfunction

**Arturo J Cardounel** , UPMC, Pittsburgh, PA; Edgar Aranda-Michel, Rishab Humar, Walter Navid, Arman Kilic, Univ of Pittsburgh, Pittsburgh, PA; Joon Lee, UPMC, Pittsburgh, PA; Thomas G Gleason, UPMC Shadyside, Pittsburgh, PA; Ibrahim Sultan, Univ of Pittsburgh, Pittsburgh, PA

12:30 PM

Board # 4291

Domain 1 of Thrombomodulin Reduces Acute Lung Injury Without Anticoagulant Effects in a Rat Cardiopulmonary Bypass Model

**Tatsuya Itoanga** , Hidetoshi Masumoto, Graduate Sch of Med, Kyoto Univ, Kyoto, Japan; Kazuhiro Yamazaki, Tadashi Ikeda, Kenji Minatoya, Kyoto Univ, Kyoto, Japan

12:30 PM

Board # 4292

Transesophageal Echocardiography, Mortality and Length of Hospitalization After Cardiac Valve Surgery

**Emily J MacKay** , Nimesh D Desai, Mark D Neuman, Jacob T Gutsche, Prakash A Patel, John G Augoustides, Peter W Groeneveld, Univ of Pennsylvania, Philadelphia, PA

# Abstract Poster Session

## EP.APS.11 - Novel Approches to Cardiovascular Risk Prediction & Prevention: Looking Beyond the Traditional Risk Factors

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 3030

Metabolomic Profiles of Coronary Artery Calcium and Incident Coronary Heart Disease in African Americans: The Jackson Heart Study

**Daniel E Cruz** , Bennet Peterson, BIDMC, Boston, MA; Debby Ngo, Beth Israel Deaconess, Boston, MA; Mark Benson, Beth Israel Deaconess Medical Cente, Boston, MA; Zsu Zsu Chen, Usman Tahir, BIDMC, Boston, MA; Yan Gao, Jackson, MS; Thomas J Wang, Vanderbilt Univ Medical Cente, Nashville, TN; Adolfo Correa, U of Mississippi Medical Ctr, Jackson, MS; Clary Clish, Broad Inst of MIT and Harvard, Cambridge, MA; James Wilson, Univ of Mississippi Medical C, Jackson, MS; Robert E Gerszten, Beth Israel Deaconess Medical Cente, Boston, MA

12:30 PM

Board # 3031

Microvesicle Levels in the Blood Are Associated With Risk of Ischemic Stroke in the Framingham Study

**Hugo J Aparicio** , Jayandra J Himali, Boston Univ, Boston, MA; Nicolas Amabile, Inst Mutualiste Montsouris, Paris, France; Matthew P Pase, The Florey Inst for Neuroscience and Mental Health, Parkville, Australia; Jose Rafael Romero, Boston Univ Sch of Med, Boston, MA; Claudia L Satizabal, Univ of Texas Health San Antonio, San Antonio, TX; Susan Cheng, Cedars-Sinai Medical Ctr, Los Angeles, CA; Charles DeCarli, UC-Davis, Sacramento, CA; Thomas J Wang, Vanderbilt Univ Medical Ctr, Nashville, TN; Vasan S Ramachandran, Boston Univ Sch of Med, Boston, MA; Alexa Beiser, Boston Univ Sch of Public Health, Boston, MA; Chantal M Boulanger, Paris Cardiovascular Res Ctr, Paris Cedex 15, France; Sudha Seshadri, UT Health San Antonio, San Antonio, TX

12:30 PM

Board # 3032

Uridine is Associated With Decreased Risk of Incident Coronary Heart Disease in an African American Cohort: Metabolomic Findings From the Jackson Heart Study

**Daniel E Cruz** , BIDMC, Boston, MA; Bing Yu, Univ of TX Health Sci Ctr Houston, Houston, TX; Bennet Peterson, BIDMC, Boston, MA; Debby Ngo, Beth Israel Deaconess, Boston, MA; Mark Benson, Beth Israel Deaconess Medical Cente, Boston, MA; Zsu Zsu Chen, Usman Tahir, BIDMC, Boston, MA; Yan Gao, Jackson, MS; Thomas J Wang, Clary Clish, Vanderbilt Univ Medical Cente, Nashville, TN; Adolfo Correa, U of Mississippi Medical Ctr, Jackson, MS; James Wilson, Univ of Mississippi Medical C, Jackson, MS; Robert E Gerszten, Beth Israel Deaconess Medical Cente, Boston, MA

12:30 PM

Board # 3033

Association of Exhaled Carbon Monoxide With Ideal Cardiovascular Health, Biomarkers and Incidence of Heart Failure in the Framingham Offspring Study

**Bradley Tun** , Boston Univ Sch of Med and Boston Medical Ctr, Boston, MA; Rachel Ehrbar, Boston Univ Sch of Public Health, Boston, MA; Vasan S Ramachandran, Vanessa Xanthakis, Section of Preventive Med and Epidemiology, Boston, MA

12:30 PM

Board # 3034

Renal Tubulointerstitial Damage is Associated With the Occurrence of Cardiac Events

**Tsuyoshi Kobayashi** , Takamitsu Nakamura, Serina Ono, Takeo Horikoshi, Aki Kobayashi, Mika Futamata, Toru Yoshizaki, Yosuke Watanabe, Manabu Uematsu, Jyuntaro Deyama, Daisuke Fujioka, Yukio Saito, Kazuto Nakamura, Kenichi Kawabata, Jyunei Obata, Kiyotaka Kugiyama, Univ of Yamanashi, Yamanashi, Japan

12:30 PM

Board # 3035

Characterization of Salivary Microbiota in Patients With Atherosclerosis and Its Potential as a Biomarker

**Masaaki Hoshiga** , Nahoko Kato-Kogoe, Shoichi Sakaguchi, Kuniyasu Kamiya, Michi Omori, Akemi Nitta, Yanhong Gu, Keisuke Fukui, Yuri Ito, Takashi Nakano, Junko Tamaki, Takaaki Ueno, Osaka Medical Coll, Osaka, Japan

12:30 PM

Board # 3036

Double Product Privilege in Predicting All-cause and Cardiovascular Disease Mortality Compare to Heart Rate and Blood Pressure Separately, the Nippon-data 80 Study

**Yiwei Liu** , Daisuke Sugiyama, Aya Hirata, Keio Univ, Tokyo, Japan; Katsuyuki Miura, Shiga Univ of Medical Science, Otsushi, Japan; Hirotsugu Ueshima, Shiga Univ of Med Sch, Otsu, Japan; Aya Kadota, Shiga Univ of Medical Science, Otsu, Japan; Takayoshi Ohkubo, Tohoku Univ Hosp, Tokyo, Japan; Akita Okayama, Osaka Univ, Osaka, Japan; Keiko Kondo, Shiga Univ of Medical Science, Ostu, Japan; Tomonori Okamura, Keio Univ, Tokyo, Japan

12:30 PM

Board # 3037

Intrinsic Frequencies of Carotid Pressure Waveforms Predict Cardiovascular Disease Events: The Framingham Heart Study

**Leroy L Cooper** , Vassar Coll, Poughkeepsie, NY; Jian Rong, Boston Univ and NHLBI's Framingham Heart Study, Framingham, MA; Niema M Pahlevan, Univ of Southern California, Los Angeles, CA; Derek G Rinderknecht, California Inst of Technology, Pasadena, CA; Emelia J Benjamin, Boston Univ and NHLBI's Framingham Heart Study, Boston, MA; Naomi M Hamburg, Boston Univ Sch of Med, Boston, MA; Vasan S Ramachandran, Boston Univ and NHLBI's Framingham Heart Study, Framingham, MA; Martin G Larson, Boston Univ Sch of Public Health, Boston, MA; Morteza Gharib, California Inst of Technology, Pasadena, CA; Gary F Mitchell, Cardiovascular Engineering, Inc., Norwood, MA

12:30 PM

Board # 3038

The Associations Between Endogenous Sex Hormone Levels and FGF-23 Among Women and Men in the Multi-Ethnic Study of Atherosclerosis

**Oluseye Ogunmoroti** , Johns Hopkins Univ, Baltimore, MD; Olatokunbo Osibogun, Florida Intl Univ, Miami, FL; Di Zhao, Johns Hopkins Univ, Baltimore, MD; Rupal C Mehta, Northwestern Univ, Chicago, IL; Pamela Ouyang, Johns Hopkins Univ, Baltimore, MD; Pamela L Lutsey, Univ of Minnesota, Minneapolis, MN; Cassianne Robinson-Cohen, Vanderbilt Univ, Nashville, TN; Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD

12:30 PM

Board # 3039

Low Plasma Homoarginine is Associated With Total Mortality in the General Population: The Framingham Offspring Study

**Rainer H Boeger** , Juliane Hannemann, Univ Medical Ctr Hamburg, Hamburg, Germany; Rebecca J. Song, Boston Univ Sch of Public Health, Boston, MA; Vanessa Xanthakis, BU Sch of Med, Boston, MA; Edzard Schwedhelm, Univ Medical Ctr Hamburg, Hamburg, Germany; Vasan S Ramachandran, Framingham Heart Study, Framingham, MA

12:30 PM

Board # 3040

What's in a Dotphrase? Evaluation of a Note-Based Ascvd Risk Calculation Tool

**Cody Dashiell-Earp** , Lauren Drake, Susan Osman, Megan Branda, Hilary Chrastil, Richard Altman, Carmen Lewis, Univ of Colorado Denver, Aurora, CO

# Abstract Poster Session

## VA.APS.03 - Pathways to Improved Outcomes in Venous Thromboembolism: The Year in Discovery Part I

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4333

Extended Thromboprophylaxis in Hospitalized Patients With Heart Failure: A Retrospective Analysis of the Magellan Study

**Alex C Spyropoulos** , Northwell Health at Lenox Hill Hosp, New York, NY; Gary Raskob, Univ of Oklahoma, Oklahoma City, OK; Theodore Spiro, Bayer US LLC, Whippany, NJ; Jianfeng Xu, Janssen Res & Development, LLC, Raritan, NJ; Yoriko De Sanctis, Bayer US LLC, Whippany, NJ; John Albanese, Janssen Res & Development, LLC, Raritan, NJ; Alexandre Mebazaa, Univ de Paris, Paris, France; Elliot S Barnathan, Janssen Res & Development, LLC, Raritan, NJ

12:30 PM

Board # 4334

Rivaroxaban for Extended Thromboprophylaxis After Hospitalization for Medical Illness: Pooled Analysis of Mortality and Major Thromboembolic Events in 16,496 Patients From the MAGELLAN and MARINER Trials

**Gary E Raskob** , Univ of Oklahoma, Oklahoma City, OK; Alex Spyropoulos, Northwell Health at Lenox Hill Hosp, NY, NY; Alexander T Cohen, King's Coll Hosp, London SE1 7EH, United Kingdom; Theodore Spiro, Bayer US LLC, Whippany, NJ; Wentao Lu, Janssen Res & Development, LLC, Raritan, NJ; Bennett Levitan, Janssen Res & Development, LLC, Titusville, NJ; Eun Young Suh, Elliot S Barnathan, Janssen Res & Development, LLC, Raritan, NJ; for the MAGELLAN and MARINER Investigators

12:30 PM

Board # 4335

Effectiveness and Safety of Standard and Reduced Dose Non-Vitamin K Oral Anticoagulants versus Warfarin in Non-Valvular Atrial Fibrillation - An International Comparative Cohort Study in the Scandinavian Countries

**Søren P Johnsen** , Aalborg Univ, Aalborg, Denmark; Morten Madsen, Aarhus Univ Hosp, Aarhus N; Marie Linder, Karolinska Instt, Stockholm, Sweden; Gerhard Sulo, Norwegian Inst of Public Health, Bergen, Norway; Waleed Ghanima, Østfold Hosp Trust, Fredrikstad, Norway; Gunnar H Gislason, Gentofte Univ Hosp, Hellerup, Denmark; Sigrun Halvorsen, Oslo Univ Hosp, Oslo, Norway; Stefan Hans Hohnloser, Goethe Univ Theodor Stern Kai, Frankfurt, Germany; Aaron Jenkins, Pfizer Ltd, Tadworth, United Kingdom; Faris Al-Khalili, Sophiahemmets Hosp, Stockholm, Sweden; Grethe S Tell, Univ of Bergen, Bergen, Norway; Vera Ehrenstein, Aarhus Univ Hosp, Aarhus N, Denmark

12:30 PM

Board # 4336

Safety and Effectiveness of Exercise Therapy After Acute Pulmonary Embolism

**Rafael S Cires-Drouet** , Steven Prior, Minerva Mayorga-Carlin, Univ of Maryland, Baltimore, MD; Kathleen Dondero, Towson Univ, Baltimore, MD; Emily Redding, Rachel White, Shahab Toursavadkohi, Shahab Toursavadkohi, John Sorkin, Brajesh Lal, Univ of Maryland, Baltimore, MD

12:30 PM

Board # 4337

Use of the International Medical Prevention Registry on Venous Thromboembolism (IMPROVE) Venous Thromboembolism Risk Model and Elevated D-Dimer to Identify a High Venous Thromboembolism Risk in an Acutely Ill Medical Population for Extended Thromboprophylaxis

**Alex C Spyropoulos** , Northwell Health at Lenox Hill Hosp, New York, NY; Gary Raskob, Univ of Oklahoma, Oklahoma City, OK; Theodore Spiro, Yoriko De Sanctis, Bayer US LLC, Whippany, NJ; Jianfeng Xu, Colleen Peluso, Elliot S Barnathan, Janssen Res & Development, LLC, Raritan, NJ

12:30 PM

Board # 4338

Treatment Patterns of Discontinuation in New Users of Oral Anticoagulants (OACs) in Patients With Non-Valvular Atrial Fibrillation (NVAF): Real-Word Evidence From NAXOS French Study

**Nicolas Danchin** , Hosp Europeen Georges Pompidou, Paris, France; Isabelle Mahe, Hop Louis Mourier, Colombes, France; Olivier Hanon, Broca Hosp, Paris, France; Philippe Gabrie Steg, Hop Bichat, Paris Cedex 18, France; Bruno Falissard, Inserm U669, Paris, France; Manon Belhassen, Flore Jacoud, Maeva Nolin, Marine Ginoux, Faustine Dalon, PELyon, Lyon, France; Cinira Lefevre, Bristol Myers-Squibb, Rueil-Malmaison, France; François-Emery Cotte, Sabrina Gollety, Bristol-Myers Squibb, Rueil Malmaison, France; Eric Van Ganse, PELyon, Lyon, France

12:30 PM

Board # 4339

Effectiveness and Safety of Non-Vitamin K Oral Anticoagulants versus Warfarin According to Patient Risk Profile in Non-Valvular Atrial Fibrillation - An International Comparative Cohort Study in the Scandinavian Countries

**Søren Paaske Johnsen** , Aalborg Univ, Aalborg, Denmark; Morten Madsen, Aarhus Univ Hosp, Aarhus N; Marie Linder, Karolinska Instt, Stockholm, Sweden; Gerhard Sulo, Norwegian Inst of Public Health, Bergen, Norway; Waleed Ghanima, Østfold Hosp Trust, Fredrikstad, Norway; Gunnar H Gislason, Gentofte Univ Hosp, Hellerup, Denmark; Sigrun Halvorsen, Oslo Univ Hosp, Oslo, Norway; Stefan Hans Hohnloser, Goethe Univ Theodor Stern Kai, Frankfurt, Germany; Aaron Jenkins, Pfizer Ltd, Tadworth, United Kingdom; Faris Al-Khalili, Sophiahemmets Hosp, Stockholm, Sweden; Grethe S Tell, Univ of Bergen, Bergen, Norway; Vera Ehrenstein, Aarhus Univ Hosp, Aarhus N, Denmark

12:30 PM

Board # 4340

Anti-factor Xa Activity Value At Peak And Trough Times In High Risk Patients With Venous Thromboembolism On Apixaban Therapy

**Ryohei Ono** , Matsudo City General Hosp, Chiba, Japan; Kenichi Fukushima, Matsudo City General Hosp, matsudo city, Japan; Tatsuro Yamazaki, Hidehisa Takahashi, Yasuhiko Hori, Matsudo City General Hosp, Chiba, Japan

12:30 PM

Board # 4341

Antiplatelet Therapy Prior to Presentation is Associated With Higher Severity Pulmonary Embolism

**Kevin Soriano** , Isabel Balachandran, Andrew Dicks, Anuradha Godishala, Jaya Kanduri, Andrew Locke, Beth Israel Deaconess Medical Ctr, Boston, MA; Mason Marcus, BIDMC, Boston, MA; Tyler Mehegan, Abby Pribish, Kelsey Sack, Cara Wiest, Brett Carroll, Beth Israel Deaconess Medical Ctr, Boston, MA

12:30 PM

Board # 4342

Chronic Beta Blocker Use in Acute Pulmonary Embolism

**Jaya Kanduri** , Inbar Raber, BIDMC, Boston, MA; Sebastian Beyer, Beth Israel Deaconess Medical Cente, Boston, MA; Isabel Balachandran, Cara Wiest, Tyler Mehegan, Andrew Locke, Anuradha Godishala, Kevin Soriano, Andrew Dicks, Kelsey Sack, Abby Pribish, Mason Marcus, Brett Carroll, BIDMC, Boston, MA

12:30 PM

Poster Professor

Gregory Piazza, Boston, MA

12:30 PM

Board # 4343

Evaluation of Centhaquine, a Novel Resuscitative Agent, in Hemorrhagic Shock Patients

**Anil Gulati** , Pharmazz, Inc and Midwestern Univ, Downers Grove, IL; Dinesh Jain, Dayanand Medical Coll, Ludhiana, India; Nilesh Agrawal, New Era Hosp, Nagpur, India; Prashant Rahate, Seven Star Hosp, Nagpur, India; Soumen Das, Rajat Chowdhuri, Inst of Post Graduate Medical Education and Res, Kolkata, India; Madhav Prabhu, Sameer Haveri, KLE's Dr. Prabhakar Kore Hosp, Belgaum, India; Deba Dhibar, Post Graduate Inst of Medical Education and Res, Chandigarh, India; Rohit Agarwal, Oriana Hosp, Varanasi, India; Manish S Lavhale, Pharmazz, Inc., Willowbrook, IL

12:30 PM

Board # 4344

Thirty-Day Readmissions After Hospitalizations for Acute Aortic Dissection

**Nilay Kumar** , Univ of Wisconsin Sch of Med and Public Health, Madison, WI

# Abstract Poster Session

## EA.APS.13 - Pharmacologic Therapy of Arrhythmias

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2057

**Acacetin, a Potent Transient Outward Current Blocker, May Serve as a Novel Therapeutic for** KCND3 **-encoded Kv4.3 Gain-of-function-associated Brugada Syndrome**

**Dan Ye** , Wei Zhou, David J Tester, Mayo Clinic, Rochester, MN; Hector Barajas-Martinez, Lankenau Inst for Medical Res, Wynnewood, PA; Dan Hu, Renmin Hosp of Wuhan Univ, Wuhan, China; Charles N Antzelevitch, Lankenau Inst for Medical Res, Wynnewood, PA; Michael J Ackerman, Mayo Clinic, Rochester, MN

12:30 PM

Board # 2058

HBI-3000: A Novel Drug for Conversion of Atrial Fibrillation - Phase 1 Study Results

**Jay W Mason** , Univ of Utah, Salt Lake City, UT; Gary T Elliott, Galenic Strategies, San Diego, CA; Suzanne J. Romano, Boaz Mendzelevski, Robin Allgren, Mireille Gillings, HUYA Bioscience Intl, San Diego, CA; Denis Roy, Univ of Montreal, Montreal, QC

12:30 PM

Board # 2059

Direct Oral Anticoagulant Adherence of Atrial Fibrillation Patients Transitioned From Warfarin: Insights From the Veterans Health Administration

**Krishna Pundi** , Stanford Cardiovascular Inst, Stanford, CA; Alexander C Perino, Stanford Univ, Stanford, CA; Jun Fan, Susan Schmitt, Mariam Askari, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA; Karolina Szummer, Stanford Univ, Stanford, CA; Paul A Heidenreich, Palo Alto VA HCS, Palo Alto, CA; Mintu Turakhia, Stanford Univ, Palo Alto, CA

12:30 PM

Board # 2060

Minute but Continuous Systemic Inflammation Contributes to Major Bleeding Risk: The Modified ORBIT-i Score to Assess Major Bleeding Risk in Non-Valvular Atrial Fibrillation Treated With Direct Oral Anticoagulants

**Tomoaki Kobayashi** , Yohei Sotomi, Osaka Police Hosp, Osaka, Japan; Akio Hirata, Osaka Police Hosp, OSAKA, Japan; Atsushi Hirayama, Yoshiharu Higuchi, Osaka Police Hosp, Osaka, Japan

12:30 PM

Board # 2061

Multimodal Mechanisms for Rapid Conversion of Atrial Fibrillation by Pulmonary Delivery of a Novel Flecainide Formulation

**Fernanda Tessarolo Silva** , Giovanna C. Pedreira, Beth Israel Deaconess Medical Ctr, Boston, MA; Sofia A. Medeiros, Beth Israel Deaconess Medical Cente, Boston, MA; Alexandre Bortolotto, Beth Israel Deaconess Medical Ctr, Boston, MA; Bruna Araujo Silva, Beth Israel Deaconess Medical Ctr, Sao Paulo, Brazil; Alexandre Marum, Beth Israel Deaconess, Boston, MA; Bruce Nearing, Beth Israel Deaconess Medical Centr, Boston, MA; Michael Hurrey, InCarda Therapeutics, Newark, CA; Prashanti Madhavapeddi, InCarda Therapeutics Inc, Newark, CA; Carlos Schuler, InCarda Therapeutics, Inc, Newark, CA; Luiz Belardinelli, InCarda Therapeutics Inc., Newark, CA; Richard L Verrier, Beth Israel Deaconess Med Ctr, Boston, MA

12:30 PM

Board # 2062

Prevalence and Risk Factors of Silent Brain Infarction in Patients With Persistent Nonvalvular Atrial Fibrillation

**Soichiro Tamura** , Shinichi Iwata, Sera Ishikawa, Kim Andrew T, Masanori Matsuo, Tomotaka Yoshiyama, Shinichi Nonin, Asahiro Ito, Yasuhiro Izumiya, Minoru Yoshiyama, Osaka City Univ, Osaka, Japan

12:30 PM

Board # 2063

In-vitro Sorbent-Mediated Removal of Edoxaban From Human Plasma and Albumin Solution

**Alexandra A Angheloiu** , Temple Univ, Philadelphia, PA; Yanglan Tan, Univ of Massachusetts Medical Sch, Shrewsbury, MA; Cristian I. Ruse, New England Biolabs, Ipswich, MA; Scott Shaffer, Univ of Massachusetts Medical Sch, Shrewsbury, MA; George O Angheloiu, Univ of Pittsburgh Medical Ctr, Williamsport, PA

12:30 PM

Board # 2064

**The Association Study of Autoantibodies Against β** 1 **-Adrenoreceptor & M**2 **-Acetycholine Receptor and Persistent Atrial Fibrillation**

Ren-Long Wei, BenQ Medical Ctr of Suzhou, Suzhou, China; Guobin Miao, Beijing Tsinghua Changgung Hosp, Beijing, China; Ying shih Lo, Cheng Shi, Xi-Yan Liu, Fei Song, Long Chen, Wei Shi, Tuan-Ye Li, Zhi-Qiang Ma, BenQ Medical Ctr of Suzhou, Suzhou, China; **Lin Zhang** , Beijing Chao-Yang Hosp,BenQ Medical Ctr of Suzhou, Beijing, China

12:30 PM

Board # 2065

Evaluation of Anticoagulation and Amiodarone Use for New Post-operative Atrial Fibrillation After Coronary Artery Bypass Grafting

**Jason D Matos** , Susan McIlvaine, Beth Israel Deaconess Medical Ctr and Harvard Medical Sch, Boston, MA; Maria Grau-Sepulveda, Oliver Jawitz, J. Matthew Brennan, Duke Clinical Res Inst, Durham, NC; Kamal Khabbaz, Beth Israel Deaconess Medical Ctr and Harvard Medical Sch, Boston, MA; Frank W Sellke, Brown Medical Sch and Lifespan Hosp, Providence, RI; Robert Yeh, Peter Zimetbaum, Beth Israel Deaconess Medical Ctr and Harvard Medical Sch, Boston, MA

12:30 PM

Board # 2066

Combined Ranolazine and Dofetilide or Ranolazine and Sotalol in the Management of Atrial Fibrillation

**Sarfaraz Memon** , Univ of Connecticut/ Hartford Hosp, West Hartford, CT; Sonal Pruthi, Univ of Connecticut/ Hartford Hosp, Hartford, CT; Jeffrey Kluger, Hartford Hosp, Hartford, CT

12:30 PM

Board # 2067

Lower Out-of-pocket Costs Are Associated With Higher Noac Persistence in Atrial Fibrillation

**Joan Alberto Maradey** , Wake Forest Baptist Medical Ctr, Winston Salem, NC; Diego Malaver, Wake Forest Baptist Medical Ctr, Winston-Salem, NC; Daniel Nielsen, Inmar Inc., Winston Salem, NC; David M Herrington, Wake Forest Univ Sch Medical, Winston Salem, NC; Prashant Bhave, Wake Forest Sch of Med, Winston Salem, NC

12:30 PM

Poster Professor

Michael E Cain, Buffalo, NY

# Abstract Poster Session

## QU.APS.03 - Pharmacoquality and Pharmacoeconomics

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 3231

How Drug Use is Calculated Impacts Quality Assessment, Particularly in the Elderly

**Lauren Gray Gilstrap** , Dartmouth Hitchcock Medical Ctr, Lebanon, NH; Andrea M Austin, Geisel Sch of Med at Dartmouth, Lebanon, NH; Barbara M Gladders, Dartmouth Hitchcock Medical Ctr, Lebanon, NH; James O'Malley, Geisel Sch of Med at Dartmouth, Lebanon, NH; Amber M Barnato, Anna N.A. Tosteson, Jonathan S. Skinner, The Dartmouth Inst, Lebanon, NH

12:30 PM

Board # 3232

"Exposure Window Duration" and "Drug Fills Prior to Admission" Both Impact Quality Performance

**Lauren Gray Gilstrap** , Dartmouth Hitchcock Medical Ctr, Lebanon, NH; Andrea M Austin, The Dartmouth Inst, Lebanon, NH; Barbara M Gladders, Dartmouth Hitchcock Medical Ctr, Lebanon, NH; James M O'Malley, Amber M Barnato, Anna N.A. Tosteson, Jonathan S. Skinner, The Dartmouth Inst, Lebanon, NH

12:30 PM

Board # 3233

Effectiveness and Safety of Non-vitamin K Antagonist Oral Anticoagulants Among Nonvalvular Atrial Fibrillation Patients With Multimorbidity

**Steve Deitelzweig** , Ochsner Clinic Fndn, New Orleans, LA; Allison Keshishian, STATinMED Res and New York City Coll of Technology, Ann Arbor, MI; Amiee Kang, Amol Dhamane, Bristol-Myers Squibb Company, Lawrenceville, NJ; Xuemei Luo, Pfizer, Inc., Groton, CT; Christian Klem, Bristol-Myers Squibb Company, Princeton, NJ; Lisa Rosenblatt, Bristol-Myers Squibb Company, Lawrenceville, NJ; Jack Mardekian, Pfizer, Inc., New York City, NY; Jenny Jiang, Bristol-Myers Squibb Company, Lawrenceville, NJ; Huseyin Yuce, New York City Coll of Technology, New York, NY; Gregory Y.H. Lip, Liverpool Ctr for Cardiovascular Science, Univ of Liverpool and Liverpool Heart & Chest Hosp, Liverpool, United Kingdom

12:30 PM

Board # 3234

Impact of CV Mortality Risk Perception on Patient Preferences for Type 2 Diabetes Mellitus Pharmacotherapy

**Amanda Lam** , Singapore General Hosp, Singapore, Singapore; Semra Ozdemir, Naina Verghese, Drishti Baid, Duke-NUS, Singapore, Singapore; Sonali Ganguly, Phong Ching Lee, Adoree YY Lim, Ling Zhu, Singapore General Hosp, Singapore, Singapore; Eric Finkelstein, Duke Univ, Singapore, Singapore; Su-Yen Goh, Singapore General Hosp, Singapore, Singapore

12:30 PM

Board # 3235

Premature Discontinuation of Statin Therapy Among Patients Exposed to Statin Drug-Drug Interactions

**Macarius Donneyong** , Lang Li, Yuxi Zhu, Teng-Jen Chang, McKenna Guilds, Yiting Li, Wendy Xu, Shelodon Retchin, The Ohio State Univ, Columbus, OH

12:30 PM

Board # 3236

Statin Use and Atherosclerotic Cardiovascular Events in Patients With Established Atherosclerotic Heart Disease and End-stage Renal Disease on Dialysis

**Jay S Shavadia** , Univ of Saskatchewan, Saskatoon, SK, Canada; Jonathan A Wilson, Duke Clinical Res Inst, Durham, NC; Daniel Edmonston, Duke Univ, Durham, NC; Alyssa Platt, Duke Univ Sch of Med, Durham, NC; Patti Ephraim, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Rasheeda Hall, Benjamin Goldstein, Duke Univ Sch of Med, Durham, NC; Ebony Boulware, Eric D Peterson, Duke Clinical Res Inst, Chapel Hill, NC; Jane Pendergast, Duke Univ Sch of Med, Durham, NC; Julia Scialla, Duke Clinical Res Inst, Durham, NC

12:30 PM

Board # 3237

Improving Appropriate Use of Omega-3 Fatty Acids in Primary Care: Success of Online CME

**Jelena Spyropoulos** , Medscape Education, New York, NY; George Boutsalis, Medscape, New York, NY; David Anderson, Medscape Education, New York, NY

12:30 PM

Board # 3238

Statin Under Prescribing in African Americans With High ASCVD Risk in a Large Healthcare System

**Michael P Dorsch** , Univ of Michigan, Coll of Pharmacy, Ann Arbor, MI; Corey Lester, Yuting Ding, Univ of Michigan, Coll of Pharmacy, Dexter, MI; Megan Joseph, Univ of Michigan, Frankel Cardiovascular Ctr, Ann Arbor, MI; Robert Brook, Univ of Michigan, Medical Sch, Ann Arbor, MI

12:30 PM

Board # 3240

Cost-Effectiveness of Folic Acid Therapy for Primary Prevention of Stroke in Patients With Hypertension

Zhuoru Liang, Tiantian Zhang, Jinan Univ, Guangzhou, China; Tengfei Lin, China Agricultural Univ, Beijing, China; Jie Jiang, Jinan Univ, Guangzhou, China; **Zugui Zhang** , Christiana Care Health System, Newark, DE

12:30 PM

Poster Professor

Cynthia Jackevicius, Los Angeles, CA

# Abstract Poster Session

## HF.APS.21 - Prognosis and Outcome in Heart Failure

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2278

Comparison of Machine Learning Methods With Statistical Regression Models for Prediction of Readmission and Mortality in Heart Failure Patients: A Systematic Review

**Sheojung Shin** , Cassandra Freitas, Univ Health Network, Toronto, ON, Canada; Husam M Abdel-Qadir, Women's Coll Hosp, Toronto, ON, Canada; Meera Mahendiran, George A Tomlinson, Univ of Toronto, Toronto, ON, Canada; Slava Epelman, Univ Health Network, Toronto, ON, Canada; Patrick R Lawler, Peter Munk Cardiac Ctr, Toronto, ON, Canada; Filio Billia, Univ Health Network, Toronto, ON, Canada; Anthony Gramolini, Univ Toronto-TBEP, Toronto, ON, Canada; Peter C Austin, ICES, Toronto, ON, Canada; Heather J Ross, Univ Health Network, Toronto, ON, Canada; Douglas S Lee, ICES, Toronto, ON, Canada

12:30 PM

Board # 2279

Baseline Characteristics and Clinical Outcomes for Patients With Chagas Disease: Insight From the National Inpatient Sample

**Dorys Chavez** , George Washington Univ, Washington, DC; Talal Alzahrani, George Washington Univ, Arlington, VA; Arnaldo Rodriguez, St. Vincent Medical Ctr, Bridgeport, CT; Syed Quadri, George Washington Univ, Washington, DC; Joseph Krepp, The George Washington Univ, Washington, DC; Marco Mercader, George Washington Univ, Washington, DC

12:30 PM

Board # 2280

Sacubitril/Valsartan Reduces All-Cause Mortality and Hospitalizations in HFrEF Patients in a Belgian Real-Life Clinical Setting

Tahnee Sente, Ruth Van Landuyt, Marie-Anne Van Lierde, Stefaan Vancayzeele, **Michael Maris** , Novartis Pharma, Vilvoorde, Belgium

12:30 PM

Board # 2281

A Method to Meaningfully Reflect on Programmatic Transplant Performance

**Adam Custer** , Emma Cruz, Daniel Cruz, Univ of California Los Angeles, Los Angeles, CA

12:30 PM

Board # 2282

Role of 123-iodine Metaiodobenzylguanitidine Imaging and Cmr in Icd Implantation Decision Making in Heart Failure Patients

**Lucia Ilaria Birtolo** , Sapienza Univ of Rome, Rome, Italy; Paola Scarparo, Hosp, Rome, Italy; Nicolò Salvi, Hosp, Rome, Italy, Rome, Italy; Viviana Maestrini, Sara Cimino, Viviana Frantellizzi, Paolo Severino, Massimo Mancone, Giuseppe De Vincentis, Francesco Fedele, Sapienza Univ of Rome, Rome, Italy

12:30 PM

Board # 2283

Prevalence and Treatment of Iron Deficiency in Heart Failure Patients at a Large Safety-net Hospital

Nikhil Singh, Stephanie Wu, **Edward Chau** , David Shavelle, Univ of Southern California, Los Angeles, CA

12:30 PM

Board # 2284

Physicians' Appropriate Use of Echocardiography, and Subsequent Health Care Utilization and Outcomes in Heart Failure Patients

**Tharmegan Tharmaratnam** , Zachary Bouck, Women's Coll Hosp, Toronto, ON, Canada; Harindra Wijeysundera, Sunnybrook Health Sciences Ctr, Toronto, ON, Canada; Cindy X Yin, Women's Coll Hosp, Toronto, ON, Canada; Gillian C Nesbitt, Mount Sinai Hosp, Toronto, ON, Canada; Jeremy Edwards, St. Michael's Hosp, Toronto, ON, Canada; Kibar Yared, The Scarborough Hosp, Scarborough, ON, Canada; Brian Wong, Adina Weinerman, Sunnybrook Health Sciences Ctr, Toronto, ON, Canada; Paaladinesh Thavendiranathan, Univ of Toronto, Toronto, ON, Canada; Harry Rakowski, Toronto General Hosp, Toronto, ON, Canada; Paul Dorian, St Michaels Hosp, Toronto, ON, Canada; Geoff Anderson, Univ of Toronto, Toronto, ON, Canada; Peter C Austin, Sunnybrook Health Sciences Ctr, Toronto, ON, Canada; David Dudzinski, Massachusetts General Hosp, Belmont, MA; Dennis Ko, ICES, Toronto, ON, Canada; Rory Weiner, Massachusetts General Hosp, Boston, MA; Sacha Bhatia, Univ of Toronto, Toronto, ON, Canada

12:30 PM

Board # 2285

Assessment of Caregiver Burden Prior to Implantation of a Left Ventricular Assist Device: A National Survey

**Colleen K McIlvennan** , Univ of Colorado, Denver, CO; Larry A Allen, Univ Colorado Denver, Aurora, CO; Jocelyn S Thompson, Univ of Colorado Anschutz, Sacramento, CA; Monica Edwards, Russell E Glasgow, Megan A Morris, Matthew K. Wynia, Bridget S Mosley, Univ of Colorado, Aurora, CO; Dan D Matlock, Univ Colorado, Aurora, CO

12:30 PM

Board # 2286

Prognostic Impact of Echocardiographically Evaluated Congestion in Patients With Heart Failure With Preserved Ejection Fraction

**Haruhiko Abe** , Shumpei Kosugi, Kazuya Shinouchi, Tsuyoshi Mishima, Motoo Date, Yasunori Ueda, Yukihiro Koretsune, NHO Osaka Natl Hosp, Osaka, Japan; Yoshio Yasumura, Amagasaki Chuo Hosp, Amagasaki, Japan; Takahisa Yamada, Osaka General Medical Ctr, Osaka, Japan; Masaaki Uematsu, NHO Osaka Natl Hosp, Osaka, Japan; Shunsuke Tamaki, Osaka General Medical Ctr, Osaka, Japan; Yoshiharu Higuchi, Osaka Police Hosp, Osaka, Japan; Yusuke Nakagawa, Kawanishi City Hosp, Kawanishi, Japan; Hisakazu Fuji, Kobe Ekisaikai Hosp, Kobe, Japan; Masami Nishino, Osaka Rosai Hosp, Sakai, Japan; Shungo Hikoso, Daisaku Nakatani, Yasushi Sakata, Osaka Univ Grad Sch of Med, Suita, Japan

# Abstract Poster Session

## AC.APS.04 - Prognosis and Therapies for Acute Coronary Syndromes I

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Poster Professor

Dan J Fintel, Chicago, IL

12:30 PM

Board # 4000

Adjunctive Vorapaxar Therapy in Patients With Prior Myocardial Infarction Treated With Newer Generation P2y12 Receptor Inhibitors Prasugrel and Ticagrelor (VORA-PRATIC): A Prospective, Randomized, Pharmacodynamic Study

**Francesco Franchi** , Univ of Florida Jacksonville, Jacksonville, FL; Fabiana Rollini, Univ of Florida Jacksonville, Jacksonville, FL; Gabriel Faz, Univ of Florida, San Antonio, TX; Jose Rivas, Andrea Rivas, Malhar Agarwal, Maryuri Briceno, Mustafa Wali, Ahmed Nawaz, Gabriel Silva, Zubair Shaikh, Naji Maaliki, Kerolos Fahmi, Univ of Florida, Jacksonville, FL; Latonya Been, Univ of florida, jacksonville, FL; Andres Pineda, Siva Suryadevara, Daniel Soffer, Martin Zenni, Univ of Florida, Jacksonville, FL; Lisa K Jennings, CirQuest Labs, Memphis, TN; Theodore Bass, Shands Jacksonville, Jacksonville, FL; Dominick Joseph Angiolillo, Univ of Florida, Jacksonville, FL

12:30 PM

Board # 4001

Impact of Proteinuria and Acute Kidney Injury on Adverse Cardiovascular Events in Chronic Kidney Disease Patients With Acute Myocardial Infarction-results From J-MINUET Substudy-

**Ryota Sato** , Kenji Sakamoto, Kumamoto Univ Hosp, Kumamoto, Japan; Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan; Koichi Nakao, Saiseikai Kumamoto Hosp, Kumamoto, Japan; Yukio Ozaki, Fujita Health Univ Hosp, Toyoake, Japan; Kazuo Kimura, Yokohama City Univ Medical Ctr, Yokohama, Japan; Junya Ako, Kitasato Univ, Kanagawa, Japan; Teruo Noguchi, Natl Cerebral & Cardiovascular Ctr, Suita, Japan; Satoshi Yasuda, Natl Cereb Cardiovascular Ctr, Osaka, Japan; Satoru Suwa, Juntendo Univ Shizuoka Hosp, Sizuoka city, Japan; Kazuteru Fujimoto, Natl Hosp Organization Kumamoto Medical Ctr, Kumamoto city, Japan; Yasuharu Nakama, Hiroshima City Hosp, Hiroshima city, Japan; Takashi Morita, Osaka General Medical Ctr, Osaka, Japan; Wataru Shimizu, Nippon Medical Sch, Tokyo, Japan; Yoshihiko Saito, Nara Medical Univ, Kashihara, Japan; Atsushi Hirohata, Sakakibara Heart Inst, Okayama, Japan; Yasuhiro Morita, Ogaki Municipal Hosp, Gifu, Japan; Teruo Inoue, Koshigaya Hosp, Koshigaya, Japan; Atsunori Okamura, Sakurabashi Watanabe Hosp, Osaka, Japan; Toshiaki Mano, Kansai Rosai Hosp, Hyogo, Japan; Kunihiro Nishimura, NCVC, Suita, Japan; Yoshihiro Miyamoto, Natl Cerebral and Cardiovascular, Suita, Japan; Hisao Ogawa, Natl Cerebral and Cardiovascular, Suita Osaka, Japan; Masaharu Ishihara, Hyogo Coll of Med, Nishinomiya, Japan

12:30 PM

Board # 4002

The Real World Clopidogrel and Prasugrel Effects in Japanese Acute Coronary Syndrome Patients

**Kenshi Yamanaga** , Kenji Sakamoto, Ryota Sato, Suguru Nagamatsu, Takayoshi Yamashita, Kota Motozato, Koichiro Fujisue, Daisuke Sueta, Seiji Takashio, Satoshi Araki, Kumamoto Univ, Kumamoto, Japan; Eiichiro Yamamoto, Kumamoto Univ Hosp, Kumamoto, Japan; Koichi Kaikita, Seiji Hokimoto, Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

12:30 PM

Board # 4003

Incidence and Costs Associated With 30-Day Unplanned Readmission in Relation to MI Presentation With NSTEMI versus STEMI in the United States: A Population-Based Cohort Study

Karthik Seetharam, Mount Sinai Medical Ctr, New York, NY; Annapoorna Kini, Mount Sinai, New York, NY; Roxana Mehran, Icahn Sch of Med Mt Sinai, New York, NY; Jacqueline E Tamis-Holland, Mount Sinai Saint Luke s Hosp, New York, NY; Matthew Tomey, The Mount Sinai Hosp, New York, NY; Nitin Barman, Jeffrey Bander, Joseph Sweeny, Mount Sinai Medical Ctr, New York, NY; George Dangas, Samin K. Sharma, Mount Sinai Hosp, New York, NY; **Usman Baber** , Mount Sinai Medical Ctr, New York, NY

12:30 PM

Board # 4004

Clinical and Angiographic Features of Out-of-hospital Cardiac Arrest in Patients With Acute Myocardial Infarction

**Shumpei Kosugi** , Kazuya Shinouchi, Haruhiko Abe, Tsuyoshi Mishima, Tatsuhisa Ozaki, Kotaro Takayasu, Yoshinori Iida, Takuya Ohashi, Chieko Toriyama, Masayuki Nakamura, Motoo Date, Yasunori Ueda, Masaaki Uematsu, Yukihiro Koretsune, Natl Hosp Organization Osaka Natl Hosp, Osaka, Japan

12:30 PM

Board # 4005

Impact of Geriatric Nutrition Risk Index on Long-term Prognosis in Patients With Acute Myocardial Infarction

**Takuya Ando** , Kazuhiko Nakazato, Takatoyo Kiko, Takeshi Shimizu, Akiomi Yoshihisa, Takayoshi Yamaki, Hiroyuki Kunii, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

12:30 PM

Board # 4006

Investigation of Pre-procedural Determinants Associated With Resultant No-reflow Phenomenon Following Primary Angioplasty for Acute Myocardial Infraction

**Masanobu Niiyama** , Yorihiko Koeda, Tomonori Itoh, Yoshihiro Morino, Iwate Medical Univ, Morioka, Japan

12:30 PM

Board # 4007

Impact of PRECISE-DAPT Score on Long-term Prognosis in Patients With Acute Myocardial Infarction

**Takuya Ando** , Kazuhiko Nakazato, Takatoyo Kiko, Takeshi Shimizu, Akiomi Yoshihisa, Takayoshi Yamaki, Hiroyuki Kunii, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

12:30 PM

Board # 4008

Validation of Complete Blood Count Datum as a Key Factor in Early Risk Stratification of Patients With ST-Elevation Myocardial Infarction

Kyung Hoon Cho, Myung Ho Jeong, Chonnam Natl Univ Hosp, Gwangju, Korea, Republic of; **Min Chul Kim** , Chonnam Natl Univ. Hosp., Gwangju, Korea, Republic of; Doo Sun Sim, Chonnam Natl Univ Hosp, Gwangju, Korea, Democratic People's Republic of; Young Joon Hong, Chonnam Natl Univ Hosp., Gwangju; Ju Han Kim, Chonnam Natl Univ Hospita, Gwangju, Korea, Republic of; Youngkeun Ahn, Chonnam Natl Univ Hosp, Gwangju, Korea, Republic of; KAMIR-NIH Investigators

12:30 PM

Board # 4009

Impact of Triple Antiplatelet Therapy on Multivessel Coronary Artery Intervention in Acute Myocardial Infarction Patients

**Seung Woon Rha** , Kareem Abdelshafi, Byoung Geol Choi, Se Yeon Choi, Jae Kyeong Byun, Jinah Cha, Yoonjee Park, Dong Oh Kang, Won-Young Jang, Woohyeun Kim, Jah Yeon Choi, Jin Oh Na, Cheol Ung Choi, Chang Gyu Park, Hong Seog Seo, Korea Univ Guro Hosp, Seoul, Korea, Republic of

12:30 PM

Board # 4010

**Thresholds of Acute Kidney Injury in Patients With ST-elevation-myocardial-infarctions: Results From a German** STEMI **-registry**

**Johannes Schmucker** , Andreas Fach, Rico Osteresch, Tina Retzlaff, Stephan Michel, Daniela Garstka, Tineke Wettwer, Rainer Hambrecht, Harm Wienbergen, Bremer Inst für Herz- und Kreislaufforschung am Klinikum Links der Weser, Bremen, Germany

12:30 PM

Board # 4011

Racial/Ethnic Disparities in Statin Adherence After Myocardial Infarction and Association With Mortality

Rikin Tank, Cheng Chen, Derek Phan, David Wee, Lewei Duan, Bryan Lam, **Ming Sum Lee** , Kaiser Permanente, Los Angeles, CA

# Abstract Poster Session

## HF.APS.23 - Risk Factors for Development and Outcome of Heart Failure

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2297

Possible Role of Increased Urine Albumin Excretion on Admission Due to Acute Decompensated Heart Failure as a Predictive Marker of Re-Hospitalization

**Yuki Matsumoto** , Hyogo Coll of Med, Nishinomiya-shi, Japan; Masanori Asakura, Hyogo Coll of Med, Hyogo, Japan; Yoshiyuki Orihara, Hyogo Coll of Med, Nishinomiya-shi, Japan; Yoshitaka Okuhara, Hyogo Coll of Med, Nishinomiya City, Japan; Kazunori Kashiwase, Masaharu Ishihara, Hyogo Coll of Med, Nishinomiya, Japan

12:30 PM

Board # 2298

Incremental Prognostic Value of Serum Cholinesterase Level Over Maggic Risk Score in Patients With Acute Decompensated Heart Failure: Insights From Osaka Prefectural Acute Heart Failure Registry (OPAR)

**Masahiro Seo** , Osaka General Medical Ctr, Osaka City, Japan; Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masatake Fukunami, Osaka General Medical Ctr, Osaka City, Japan

12:30 PM

Board # 2299

Diet, Nutrients, and Symptoms in Persons With Heart Failure

**Erica Davis** , Sandra B Dunbar, Melinda Higgins, Carolyn M. Reilly, Emory Univ, Atlanta, GA

12:30 PM

Board # 2300

Impacts of Urinary Angiotensinogen as a Biomarker for Monitoring the Clinical Status in Patients With Congestive Heart Failure

**Shota Yokoyama** , Ryo Kawakami, Yuichi Miyake, Makoto Ishizawa, Teppei Tsuji, Kaori Ishikawa, Kazushi Murakami, Takahisa Noma, Tetsuo Minamino, Kagawa Univ Hosp, Takamatsu, Japan

12:30 PM

Board # 2301

Outcomes of Clostridium Difficile Infection in Patients With Heart Failure: A Nationwide Analysis

**Devesh Rai** , Muhammad Waqas Tahir, Amit Bansal, Qiu Tong, Mohammad Abu Sheikha, Raseen Tariq, Rochester General Hosp, Rochester, NY

12:30 PM

Board # 2302

Personalized Treatment for Heart Failure With Preserved Ejection Fraction Using Deep Reinforcement Learning

**Hui Ren** , Sijia Yu, Xiang Li, Massachusetts General Hosp, Boston, MA; Wei Qiu, Peking Univ, Beijing, China; Aoxiao Zhong, Harvard Univ, Cambridge, MA; Ning Guo, Quanzheng Li, Massachusetts General Hosp, Boston, MA

12:30 PM

Board # 2303

Residual Gensini Score is Associated With Long Term Cardiac Mortality in Patients With Ischemic Heart Failure

**Tetsuro Yokokawa** , Akiomi Yoshihisa, Takuya Ando, Fukushima Medical Univ, Fukushima, Japan; Takatoyo Kiko, Fukushima Medical Univ, Fukushima city, Japan; Takeshi Shimizu, Fukushima Medical Univ, Fukushima, Japan; Takayoshi Yamaki, Fukushima Medical Univ, Fukushina, Japan; Hiroyuki Kunii, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

12:30 PM

Board # 2304

Vitamin Deficiency is Associated With a Higher Risk for Hospitalizations in Veterans With Heart Failure

Raquel Aparicio-Ugarriza, **Douglas Salguero** , Yaqub Nadeem Mohammed, Univ of Miami, miami, FL; Juliana Ferri-Guerra, Univ of Miami, Miami, FL; Dhanya Baskaran, VA Health Care System, Miami, FL; Seyed Abbas Mirabbasi, Alexis Rodriguez, Jorge G. Ruiz, Univ of Miami, Miami, FL

12:30 PM

Board # 2305

Self-Reported Engagement in Exercise is Associated With Longer Event Free-Survival in Heart Failure Patients With Poor Functional Capacity

**Ifeanyi Madujibeya** , Misook Chung, Univ of Kentucky, Lexington, KY

12:30 PM

Board # 2306

Cumulative Blood Pressure From Mid-to-late Life and Late Life Risk of Hfpef And Hfref: The Atherosclerosis Risk in Communities (ARIC) Study

**Kanako Teramoto** , St. Marianna Univ Sch of Med, Kawasaki, Japan; Wilson Nadruz Jr., Univ of Campinas, Sao Paulo, Brazil; Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD; Brian Claggett, Jenine E John, Hicham Skali, Scott D Solomon, Brigham and Women's Hosp, Boston, MA; Susan Cheng, Cedars-Sinai Medical Ctr, Los Angeles, CA; Amil M Shah, Brigham and Women's Hosp, Boston, MA

12:30 PM

Poster Professor

Flora Sam, Boston, MA

# Abstract Poster Session

## HF.APS.11 - Risk Stratification and Outcome in Heart Failure

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2176

Additional Prognostic Significance of Cognitive Function to Ahead Risk Score in Patients With Acute Decompensated Heart Failure: Insights From Osaka Prefectural Acute Heart Failure Registry (OPAR)

**Masahiro Seo** , Osaka General Medical Ctr, Osaka City, Japan; Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masatake Fukunami, Osaka General Medical Ctr, Osaka City, Japan

12:30 PM

Board # 2177

Which Factors Are Correlated With One-Year Preserved Renal Function in Acute Heart Failure Patients With Preserved Ejection Fraction? - Insights From PURSUIT-HFpEF Registry

**Kyosuke Yanagawa** , Ryu Shutta, Hitoshi Nakamura, Yutaka Matsuhiro, Koji Yasumoto, Akihiro Tanaka, Naotaka Okamoto, Daisuke Nakamura, Yasuharu Matsunagawa, Masamichi Yano, Masaki Yamato, Yasuyuki Egami, Masami Nishino, Jun Tanouchi, Osaka Rosai Hosp, Sakai, Japan; Yoshio Yasumura, Amagasaki Chuo Hosp, Amagasaki, Japan; Takahisa Yamada, Osaka General Medical Ctr, Osaka, Japan; Masaaki Uematsu, Natl Hosp Organization Osaka Natl Hosp, Osaka, Japan; Shunsuke Tamaki, Osaka General Medical Ctr, Osaka, Japan; Yoshiharu Higuchi, Osaka Police Hosp, Osaka, Japan; Yusuke Nakagawa, Kawanishi City Hosp, Kawanishi, Japan; Hisakazu Fuji, Kobe Ekisaikai Hosp, Kobe, Japan; Shungo Hikoso, Daisaku Nakatani, Yasushi Sakata, Osaka Univ Graduate Sch of Med, Suita, Japan

12:30 PM

Board # 2178

Association Between Malnutrition and Exercise Intolerance in Patients With Idiopathic Dilated Cardiomyopathy

**Masahiro Seo** , Osaka General Medical Ctr, Osaka City, Japan; Takahisa Yamada, Shunsuke Tamaki, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masatake Fukunami, Tomohito Otani, Osaka General Medical Ctr, Osaka City, Japan; kei nakamoto, Osaka Univ, Suita, Japan; Shozo Konishi, Osaka Univ Graduate Sch of Med, Suits City, Osaka, Japan; Yasushi Sakata, Osaka General Medical Ctr, Suita, Japan

12:30 PM

Board # 2179

Heart Failure Patients Undergoing Transcatheter Valve Intervention: Prognostic Role of HLM Classification

Paolo Severino, Sapienza Univ, Rome, Italy; **Mariateresa Pucci** , Policlinico Umberto I, Rome, Italy; Fabio Infusino, Umberto I Hosp, Sapienza, Rome, Italy; Marco Valerio Mariani, Policlinico Umberto I, Rome, Italy; Andrea d'Amato, Sapienza Univ of Rome, Rome, Italy; Rossana Scarpati, Lucrezia Netti, Danilo Alunni Fegatelli, Viviana Maestrini, Policlinico Umberto I, Rome, Italy; Massimo Mancone, Francesco Fedele, Sapienza Univ of Rome, Rome, Italy

12:30 PM

Board # 2180

Fluid Resuscitation in CHF Patients Presenting With Sepsis

**Mulham Shikh Hamdon** , Wayne State Univ, Rochester Hills, MI; Toribiong Uchel, Wayne State Univ IM Residency, Rochester Hills, MI; Manishkumar Patel, Victoria Gonzalez, Lina Masso, Anubhav Jain, Wayne State Univ, Rochester Hills, MI

12:30 PM

Board # 2181

Long-term Prognostic Value of the Combination of Fibrosis-4 Index and Plasma Volume Status in Patients With Admitted for Acute Decompensated Heart Failure

**Takahisa Yamada** , Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masahiro Seo, Osaka General Medical Ctr, Osaka City, Japan; Jun Nakamura, Makoto Abe, Kyoko Yamamoto, Kiyomi Kayama, Osaka General Medical Ctr, Osaka, Japan; Masatsugu Kawahira, Osaka General Medical Ctr, Oosaka, Japan; Kazuya Tanabe, Yuto Tamura, Takeshi Fujita, Masatake Fukunami, Osaka General Medical Ctr, Osaka, Japan

12:30 PM

Board # 2182

Integrated Cross-Sectional Modeling for the Prediction of 30-Day Unplanned Readmissions or All-Cause Mortality in Primary Heart Failure

**Subhi J. Al'Aref** , Zhuoran Xu, Weill Cornell Med, New York, NY; Manasa Gummalla, Weill Cornell Med, NYC, NY; Evan Sholle, Yiye Zhang, Ruth Masterson Creber, Yongkang Zhang, Kelly Michalak, Kristina Dolan, Weill Cornell Med, New York, NY; Ashley Beecy, Weill Cornell Med, New York; Benjamin C. Lee, Weill Cornell Med, NYC, NY; Gabriel Maliakal, Dalio ICI, New York, NY; Mohit Pandey, Weill Cornell Med, NYC, NY; Gurpreet Singh, Thomas R. Campion Jr., Leslee J. Shaw, Lohendran Baskaran, Weill Cornell Med, New York, NY; James K Min, Cedars Sinai Medical Ctr, Santa Monica, CA

12:30 PM

Board # 2183

High Brain Natriuretic Peptide Level is an Independent Predictor of Long-Term Mortality and Hospitalization Due to Heart Failure in Patients With Pacemaker Implantation

**Yasuhiro Matsuda** , Masaharu Masuda, Mitsutoshi Asai, Osamu Iida, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takashi Kanda, Takuya Tsujimura, Shota Okuno, Hiroyuki Uematsu, Yuki Sato, Shodai Kawanami, Hiroki Sugae, Sho Nakao, Toshiaki Mano, Kansai Rosai Hosp, Amagasaki, Japan

12:30 PM

Board # 2184

Cardiogenic Shock Management: International Survey of Contemporary Practices

**Angie S Lobo** , Abbott Northwestern Hosp, Minneapolis, MN; Yader Sandoval, Mayo Clinic, La Crosse, WI; Jose P Henriques, Academic Medical Ctr, Amsterdam; Stavros G Drakos, U of U Sch of Med, Salt Lake Cty, UT; Iosif Taleb, Univ of Utah Sch of Med, Salt Lake City, UT; Jayant Bagai, Vanderbilt Univ Medical Ctr, Nashville, TN; Mauricio Gabriel Cohen, Univ of Miami, Miami, FL; Yiannis S Chatzizisis, Univ of Nebraska, Omaha, NE; Benjamin Sun, Minneapolis Heart Ins, Minneapolis, MN; Katarzyna Hryniewicz, Peter M Eckman, Minneapolis Heart Inst, Minneapolis, MN; Holger Thiele, Univ Leipzig - Heart Ctr, Leipzig; Emmanouil S Brilakis, Minneapolis Heart Inst, Minneapolis, MN

12:30 PM

Board # 2185

Prognostic Value of the Combination of Pulmonary-systemic Pressure Ratio and Model Of End-stage Liver Disease Excluding Inr (meld-xi) Score in Patients Admitted for Acute Decompensated Heart Failure

**Takahisa Yamada** , Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masahiro Seo, Osaka General Medical Ctr, Osaka City, Japan; Jun Nakamura, Kyoko Yamamoto, Makoto Abe, Kiyomi Kayama, Osaka General Medical Ctr, Osaka, Japan; Masatsugu Kawahira, Osaka General Medical Ctr, Oosaka, Japan; Kazuya Tanabe, Osaka General Medical Ctr, Osaka, NY; Tamura Yuto, Takeshi Fujita, Masatake Fukunami, Osaka General Medical Ctr, Osaka, Japan

# Abstract Poster Session

## NR.APS.01 - Self-Care Conundrums

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4212

Delay in Seeking Medical Care for Worsening Heart Failure Symptoms: Predictors and Association With Cardiac Events

**Chin-Yen Lin** , Univ of Kentucky, Lexington, KY; Muna Hammash, Univ of Louisville, Louisville, KY; Jennifer L. Miller, Univ of Kentucky, Lexington, KY; Melanie Schrader, Univ of Louisville, Louisville, KY; Debra K. Moser, Univ of Kentucky, Lexington, KY

12:30 PM

Board # 4213

Higher Levels of Body Awareness Are Not Sufficient to Improve Self-care Management in Patients With Heart Failure

**Kyoung Suk Lee** , Seoul Natl Univ, Seoul, Korea, Republic of; Eun-Seok Jeon, Sunkyunkwan Univ, Seoul, Korea, Republic of; Jae-Hyeong Park, Chungnam Natl Univ, Daejeon, Korea, Democratic People's Republic of; Mi Sook Jung, Hyeri Yun, Chungnam Natl Univ, Deajeon, Korea, Republic of; Zian Lee, Seoul Natl Univ, Seoul, Korea, Republic of; Jin Oh Choi, Sunkyunkwan Univ, Seoul, Korea, Republic of

12:30 PM

Board # 4214

How Does Cognition Influence Symptom Perception in Patients With Heart Failure?

**Solim Lee** , Amy Ketcham, Brittany Koons, Julie Guerin, Univ of Pennsylvania, Philadelphia, PA; Victoria Vaughan Dickson, New York Univ, New York, NY; Corrine Y Jurgens, Boston Coll, Chestnut Hill, MA; Lea Ann Matura, Barbara J Riegel, Univ of Pennsylvania, Philadelphia, PA

12:30 PM

Board # 4215

Younger Patients Are at Risk For Low Adherence to Angiotensin-converting Enzyme Inhibitor Medications: A Multi-clinic Cross-sectional Study

**Christopher Kabir** , Advocate Aurora Health Care, Chicago, IL; Nishat Fatima, Advocate Illinois Masonic Medical Ctr, Chicago, IL; Katherine Carlson, Advocate Aurora Health Care, Chicago, IL; Mohammed Samee, Advocate Illinois Masonic Medical Ctr, Chicago, IL

12:30 PM

Board # 4216

Perceptions of Patients With Heart Failure on Symptom Self-Monitoring

**Dawon Baik** , Columbia Univ, New York, NY; Meghan Reading Turchioe, Annie Myers, Weill Cornell Med, New York, NY; Lisa V. Grossman, Columbia Univ, New York, NY; Ruth Masterson Creber, Weill Cornell Med, New York, NY

12:30 PM

Board # 4217

Family Encouragement for a Healthy Diet Predicts Diet Quality in Hispanic Adults at Risk for Cardiovascular Disease

**Salman Alreshidi** , Kaitlin Voigts, Terry A Lennie, Gia Mudd-martin, Univ of Kentucky, Lexington, KY

12:30 PM

Board # 4218

Do Heart Failure Patients With Comorbid Diabetes Have Better Diet Quality and Lower Sodium Consumption Than Those Without Diabetes?

**Misook L Chung** , Jennifer L Miller, Terry A Lennie, Debra K Moser, Univ of Kentucky, Lexington, KY

12:30 PM

Board # 4219

Diet Monotony is Associated With Higher Dietary Micronutrient Deficiencies in Patients With Heart Failure

**Reem Basaqr** , D.Travis Thomas, Martha J Biddle, Debra K Moser, Terry A Lennie, Univ of Kentucky, Lexington, KY

12:30 PM

Board # 4220

Inflammatory Properties of Diet Mediate the Relationship Between Depressive Symptoms and Cardiovascular Disease Risk in Men and Women

**Junghee Kang** , Debra K Moser, Univ of Kentucky, Lexington, KY; Martha Biddle, Lexington, KY; Terry A Lennie, Univ of Kentucky, Lexington, KY; Susan Smyth, Univ of Kentucky, Lexington; Olga Vsevolozhskaya, Univ of Kentucky, Lexington, KY

12:30 PM

Board # 4221

Plasma Vitamin C And D Concentration, Oxidative Stress, Anti-inflammation, And Cardiac Event-free Survival In Patients With Heart Failure

**Eun Kyeung Song** , Univ of Ulsan, Ulsan, Korea, Republic of; Debra K Moser, Terry A Lennie, Univ of Kentucky, Lexington, KY

12:30 PM

Poster Professor

Lucinda J Graven, Tallahassee, FL

12:30 PM

Board # 4222

The Level of Function Mobility Scale for Nurse-driven Early Mobilization in Patients With Acute Cardiovascular Disease

Diana Dima, Jewish General Hosp, Montreal, QC, Canada; Joelle Berube-Dufour, Univ de Montreal, Montreal, QC, Canada; **Michael Goldfarb** , Jewish General Hosp, Montreal, QC, Canada

12:30 PM

Board # 4223

Validation of a Self-care Questionnaire for Adolescents / Young Adults With Congenital Heart Disease

**Nancy A Pike** , Paola Moreno, UCLA, Los Angeles, CA; Jennifer K Peterson, Univ of California Irvine, Irvine, CA; Nancy J Halnon, UCLA Medical Ctr, Los Angeles, CA; Alan B Lewis, Childrens Hosp LA, Los Angeles, CA; Mary A Woo, UCLA, Los Angeles, CA

12:30 PM

Board # 4224

Depression and Heart Rate Variability in Adults With Cyanotic Congenital Heart Disease

**Ju Ryoung Moon** , June Huh, Jinyoung Song, I-Seok Kang, Ji-Hyuk Yang, Tae-Gook Jun, Sung-A Chang, Seung Woo Park, Samsung Medical Ctr, Seoul, Korea, Republic of

12:30 PM

Board # 4225

Parental Satisfaction With Communication in the Pediatric Cardiac Intensive Care Unit is Associated With Parental Anxiety and Education

**Jennifer Walter** , Theodore Schall, Rui Xiao, Aaron Gabriel DeWitt, Chris Feudtner, Children's Hosp of Philadelphia, Philadelphia, PA

# Abstract Poster Session

## WS.APS.05 - Sex Differences and CHF in Women

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 3166

Gender Difference of Beta-Blocker Effect in Patients With Heart Failure Preserved Ejection Fraction

**Eisaku Harada** , Kumamoto Aging Res Inst/Kinoh Hosp, Kumamoto, Japan; Yuji Mizuno, Kumamoto Aging Res Inst, Kumamoto, Japan; Fumihito Kugimiya, Makoto Shono, Hirofumi Yasue, Kumamoto Aging Res Inst/Kinoh Hosp, Kumamoto, Japan

12:30 PM

Board # 3167

Comparisons of Clinical Features and Prognosis of Heart Failure Patients With Reduced Ejection Fraction Between Japanese Women and Men

**Yuki Kanno** , Yoshihisa Akiomi, Yasuhiro Ichijyo, Takatoyo Kiko, Yusuke Kimishima, Yu Sato, Tetsuro Yokokawa, Satoshi Abe, Tomofumi Misaka, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

12:30 PM

Board # 3168

Gender Specific Outcomes in Patients With Heart Failure and Sepsis. Real World Experience

**Jesus E Pino** , Univ of Miami/JFK Medical Ctr, West Palm Beach, FL; Fergie Ramos-Tuarez, Julio Grajeda Chavez, Jorge Saona, Endri Ceka, Kai Chen, Pedro Torres, Jorge Saona, Andres Chacon Martinez, Gretchen De Diego, Univ of Miami/JFK Medical Ctr, Atlantis, FL; Robert D Chait, Univ of Miami/JFK Medical Ctr, West Palm Bch, FL

12:30 PM

Board # 3169

Women Have a Higher Acute Mortality Rate After Intra-Aortic Balloon Pump (IABP) Use During Cardiogenic Shock

**Po-Yuan Chang** , Natl Taiwan Univ Hosp, Taipei City, Taiwan; Jung-Chi Hsu, Saint Mary's Hosp, Luodong, Taiwan; Chuhuang Chen, Texas Heart Inst, Houston, TX

12:30 PM

Board # 3170

National Trends in Readmission Rates After Acute Myocardial Infarction Hospitalizations in Heart Failure Patients

**Mohamed M Gad** , Cleveland Clinic, Cleveland, OH; Anas Saad, Cleveland Clinic Fndn, Cleveland, OH; Ahmed N Mahmoud, Univ of Washington, Seattle, WA; Islam Y Elgendy, Massachusetts General Hosp, Boston, MA; Samir R Kapadia, Cleveland Clinic, Cleveland, OH

12:30 PM

Board # 3171

Real World Analysis of Efficacy of Remote Pulmonary Artery Hemodynamic Monitoring in Female and Male Population

**Smitha Narayana Gowda** , Univ of South Dakota Sanford Sch of Med, Sioux Falls, SD; Udit Bhaskar Bhatnagar, Univ of South Dakota, Sioux Falls, SD; Adam Stys, Univ of South Dakota Sanford Sch of Med, Sioux Falls, SD; Tom Stys, Sanford Health, Sioux Falls, SD; Marian S Petrasko, Univ of South Dakota Sanford Sch of Med, Sioux Falls, SD; Naveen Rajpurohit, Sanford USD Medical Ctr, Sioux Falls, SD; Valerie Bares, Univ of South Dakota Sanford Sch of Med, Sioux Falls, SD; Orvar Jonsson, Sanford Cardiovascular Inst, Sioux Falls, SD

12:30 PM

Board # 3172

Breast Arterial Calcification and Risk of Heart Failure

**Quan Minh Bui** , UC San Diego, La Jolla, CA; Avinash Toomu, Univ of California, San Diego, San Diego, CA; Paula Anzenberg, Taelor Getz, Mohammad Eghtedari, UC San Diego, La Jolla, CA; Lori Daniels, UCSD Medical Ctr, Del Mar, CA

12:30 PM

Board # 3173

Factors Associated With Under-Enrollment of Women in Clinical Trials of Heart Failure: A Systematic Review and Meta-Analysis

**Sera Whitelaw** , Kristen Sullivan, Mohammad Alruwayeh, Yousif Eliya, Harriette GC Van Spall, McMaster Univ, Hamilton, ON, Canada

12:30 PM

Board # 3174

Representation of Women Authors in Contemporary Heart Failure Clinical Trials

**Annie H Ho** , Ayman Samman Tahhan, Emory Univ SOM, Atlanta, GA; Muthiah Vaduganathan, Brigham and Women's Hosp, Boston, MA; Stephen J Greene, Duke Univ Medical Ctr, Durham, NC; Alaaeddin Alrohaibani, Atlanta VA Medical Ctr, Decatur, GA; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; Javed Butler, Univ Mississippi Med Ctr, Jackson, MS; Christopher O'Connor, Inova Heart and Vascular Inst, Falls Church, VA; Mona Fiuzat, Inova Heart and Vascular Inst, Arlington, VA; Ileana L Pina, Detroit Medical Ctr Heart Hosp, Cleaveland Hghts, OH; JoAnn Lindenfeld, Vanderbilt Univ SOM, Nashville, TN; Mariell Jessup, American Heart Association, Dallas, TX

12:30 PM

Poster Professor

Modele O Ogunniyi, GA

# Abstract Poster Session

## WS.APS.04 - Sex Differences in CHD and Valvular Disease

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 3157

The Efficacy and Safety of Dapagliflozin in Women and Men With Type 2 Diabetes Mellitus: Insights From The DECLARE-TIMI 58 Trial

**Michelle L O'Donoghue** , Brigham and Womens Hosp, Boston, MA; Eri T Kato, Kyoto Univ Hosp, Kyoto, Japan; Ofri Mosenzon, Hadassah Hebrew Univ Hosp, Jerusalem, Israel; Sabina A Murphy, TIMI Study Group, Boston, MA; Avivit Cahn, Hadassah Hebrew Univercity Hosp, Jerusalem, Israel; Marisol Herrera Marmolejo, Torre Medica Providencia, Guadalajara, Mexico; Tsvetalina Tankova, Medical Univ - Sofia, Sofia, Bulgaria; Alena Smahelova, Faculty Hosp Hradec Kralove, Hradec Kralove, Czech Republic; Piera Angelica Merlini, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy; Ingrid Ami Gause-nilsson, Anna Maria Langkilde, Astrazeneca, Mölndal, Sweden; Darren K. K McGuire, Univ Texas Southwestern Med Ctr, Dallas, TX; John Wilding, Univ of Liverpool, Liverpool, United Kingdom; Lawrence A Leiter, St Michael's Hosp, Toronto, ON, Canada; Deepak L Bhatt, Brigham and Womens Hosp, Boston, MA; Itamar Raz, Diabetes Medical Ctr, Tel Aviv, Israel; Marc S Sabatine, TIMI Study Group, Boston, MA; Stephen D Wiviott, Brigham and Womens Hosp, Wellesley, MA

12:30 PM

Board # 3158

Clinical Implications of Dual Antiplatelet Therapy Cessation Within 12 Months of Coronary Stenting in Men and Women: A Pooled Analysis From the Platinum Diversity and Promus Element Plus Post-Approval Studies

**Rishi Chandiramani** , Davide Cao, Roxana Mehran, Moritz Blum, Anastasios Roumeliotis, Ridhima Goel, Samantha Sartori, Icahn Sch of Med at Mount Sinai, New York, NY; Scott Davis, Baptist Hosp, Little Rock, AR; Luis Tami, Res Physicians Network Alliance, Hollywood, FL; John Wang, MedStar Union Memorial Hosp, Baltimore, MD; Islam Othman, Duke Univ Health System, Durham, NC; Osvaldo Gigliotti, Seton Heart Inst, Austin, TX; Kevin Boran, Cardiovascular Consultants Heart Ctr, Fresno, CA; Henry Liberman, Emory Univ Sch of Med, Atlanta, GA; Paul Underwood, Dominic Allocco, Boston Scientific Corp, Marlborough, MA; Wayne Batchelor, Inova Heart and Vascular Inst, Falls Church, VA

12:30 PM

Board # 3159

Effects of Therapeutic Lowering of Non-High Density Lipoprotein Cholesterol on Cardiovascular Outcomes Among Women versus Men: A Meta- Regression Analysis

**Safi Ullah Khan** , West Virginia Univ, Morgantown, WV; Adeel Arshad, Rochester Regional Health/Unity Hosp, Rochester, NY; Muhammad Z Khan, West Virginia Univ, Morgantown, WV; Mohammad Shahzeb Khan, John H Stroger Jr Hosp of Cook, Chicago, IL; Victor Okunrintemi, East Carolina Univ, Greenville, NC; Eve-Marie Benson, Johns Hopkins Univ, Baltimore, MD; Roger S Blumenthal, Johns Hopkins Hosp, Baltimore, MD; Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD

12:30 PM

Board # 3161

Gender Disparities in 30-Day Readmissions and Revascularization After ST-Segment-Elevation Myocardial Infarction in the United States

**Diala Steitieh** , Daniel Lu, New York Presbyterian Hosp- Weill Cornell, NY, NY; Ilhwan Yeo, Mount Sinai, NY, NY; Luke Kwon Kim, NYP Hosp/Weill Cornell Campus, New York, NY; Nivee Amin, New York Presbyterian Hosp- Weill Cornell, NY, NY

12:30 PM

Board # 3162

Sex Differences in Acute Heart Failure and Cardiovascular Outcomes After Myocardial Infarction

**Edina Cenko** , Univ of Bologna, Bologna, Italy; Mihaela van der Schaar, Univ of Cambridge, Cambridge, United Kingdom; Jinsung Yoon, Univ of California, Los Angeles, Los Angeles, CA; Olivia Manfrini, Univ of Bologna, Bologna, Italy; Zorana Vasiljevic, Univ of Belgrade, Belgrade, Serbia; Marija Vavlukis, Univ Clinic of Cardiology, Skopje, Macedonia, The Former Yugoslav Republic of; Sasko Kedev, Univ "Ss. Cyril and Methodius", Skopje, Skopje, Macedonia, The Former Yugoslav Republic of; Davor Milicic, Universiy Cardiovascular Clinic, Zagreb; Lina Badimon, Cardiovascular Program ICCC-IRHSCSP, Barcelona, Spain; Raffaele Bugiardini, Univ of Bologna, Bologna, Italy

12:30 PM

Board # 3163

Prognostic Differences Between Men and Women With Significant Secondary Mitral Regurgitation

**Farnaz Namazi** , Pieter van der Bijl, N. Mai Vo, Suzanne E. van Wijngaarden, Nina Ajmone Marsan, Victoria Delgado, Jeroen J Bax, Leiden Univ Medical Ctr, Leiden, Netherlands

12:30 PM

Board # 3164

Sex Differences in Functional Mitral Regurgitation

**Rachna Kataria** , Montefiore Medical Ctr/Albert Einstein Coll of Med, Bronx, NY; Ari Friedman, Jacobi Medical Ctr, Bronx, NY; Elliot Wiesenfeld, Mohamed Azeem Latib, Ulrich P Jorde, Montefiore Medical Ctr/Albert Einstein Coll of Med, Bronx, NY

12:30 PM

Board # 3165

Sex-differential in Clinical Profiles, Echocardiographic Characteristics and Association With Outcomes in Centenarians

**Zhenzhen Wang** , Hon-Chi Lee, Bernard J Gersh, Eddie L Greene, Patricia A Pellikka, Jae K Oh, Vuyisile T Nkomo, Rowlens M Melduni, Mayo Clinic, Rochester, MN

12:30 PM

Poster Professor

Sharonne N Hayes, Rochester, MN

# Abstract Poster Session

## CE.APS.03 - Signaling 1

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 1100

STK25 Regulates the p38 Mapk Pathway in Human Cardiomyocytes

**Xiaokan Zhang** , Michael Kim, Columbia Univ Medical Ctr, New York, NY; Bryan Wang, Bohao Liu, Roberta Imogen Lock, Columbia Univ, New York, NY; Eric Li, Columbia Univ Medical Ctr, New York, NY; Gordana Vunjak-Novakovic, Columbia Univ, New York, NY; Barry Fine, Columbia Univ Medical Ctr, New York, NY

12:30 PM

Board # 1101

Dimerization of Gata4 Plays a Key Role in Hypertrophic Responses in Cultured Cardiomyocytes

**Satoshi Shimizu** , Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki, Masafumi Funamoto, Nurmila Sari, Kana Shimizu, Univ of Shizuoka, Shizuoka, Japan; Hiromichi Wada, Koji Hasegawa, Kyoto Medical Ctr NHO, Kyoto, Japan; Tatsuya Morimoto, Univ of Shizuoka, Shizuoka, Japan

12:30 PM

Board # 1102

Global Over-Activation of G-Protein Coupled Receptor Kinase 2 Causes Aging Related Cardiovascular Dysfunction

**Melissa Lieu** , Temple Univ, Philadelphia, PA; Christopher J Traynham, Fujirebio Diagnostics Inc, Philadelphia, PA; Claudio De Lucia, Michela Piedepalumbo, Temple Univ, Philadelphia, PA; Rajika Roy, Temple Univeristy, Philadelphia, PA; Gavin Landesberg, Temple Univ, Philadelphia, PA; Steven J Forrester, Emory Univ, Decatur, GA; Laurel Grisanti, Univ of Missouri, Columbia, MO; Erhe Gao, Satoru Eguchi, Rosario G Scalia, Walter J Koch, Temple Univ, Philadelphia, PA

12:30 PM

Board # 1103

Phospholamban Levels Build Up in the Nuclear Envelope Until Newly-Made SERCA2a Directs It to Sarcoplasmic Reticulum

**Dayang Huang** , Wenbo He, Jin Guo, Indiana Univ, Indianapolis, IN; Peng-Sheng Chen, Krannert Inst of Cardiolo, Indianapolis, IN; Steven Cala, Wayne State Univ, Detroit, MI; Zhenhui Chen, Indiana Univ, Indianapolis, IN

12:30 PM

Board # 1104

Stabilization of CaMKII-phosphorylated RyR2 By Dantrolene Prevents the Development of Age-related Cardiomyopathy in CaMKIIδc Transgenic Mice

**Yoko Sufu-Shimizu** , Shinichi Okuda, Yoko Okamoto, Takayoshi Kato, Hitoshi Uchinoumi, Tetsuro Oda, Shigeki Kobayashi, Takeshi Yamamoto, Masafumi Yano, Yamaguchi Univ, Ube, Japan

12:30 PM

Board # 1105

Heart Enriched IRF2BP2 Protects Cardiomyocytes Against Hypoxia in vitro

**Zheng Kuai** , Zhongshan Hosp, Fudan Univ, Shanghai, China; Meiting Chen, Fan Yang, Chunxiang Zhang, Univ of Alabama at Birmingham, Birmingham, AL

12:30 PM

Board # 1106

**Prostaglandin E** 2 **Receptor Ep4 Regulates Fibrotic Changes via Intracellular Calcium in Cardiac Fibroblast Cells**

**Masanari Umemura** , Kohei Osawa, Ryo Tanaka, Mayu Hikichi, Rina Nakakaji, Islam Rafikul, Yokohama City Univ Graduate Sch of Med, Yokohama, Japan; Yoshihiro Ishikawa, Yokohama City Univ, Yokohama, Japan

12:30 PM

Board # 1107

Distinct Cardiovascular Defects in Small GTPase Rap1A-Deficient C57BL/6 Mice

Shafaq Javaid, Hina Hazrat, Intl Cntr for Chem Bio Sci, Karachi, Pakistan; John A. Bauer, Mandar S. Joshi, Univ of Kentucky Coll of Med, Lexington, KY; Lawrence A. Quilliam, Indiana Univ Sch of Med, Indianapolis, IN; Yingbi Zhou, Shantou Univ Medical Coll, Guangdong, China; **Maqsood A. Chotani** , Intl Cntr for Chem Bio Sci, Karachi, Pakistan

12:30 PM

Board # 1108

Natriuretic Peptides Signaling and Forkhead O Transcription Factors Act in a Cooperative Manner to Promote Cardiomyocyte Cell Cycle Re-entry in the Early Postnatal Mouse Heart

**Mir Shawkat Ali** , Daniela Liccardo, Tongtong Cao, Ying Tian, Temple Univ Lewis Katz Sch of Med, Philadelphia, PA

12:30 PM

Poster Professor

John W Calvert, Suwanee, GA

12:30 PM

Board # 1110

Label-Free Tomographic Imaging is Applicable to Therapeutic Evaluation of Targeted Nanodrugs in Lipid-Laden Foam Cells

**Jae Won Ahn** , Chung-Ang Univ, Gyeonggi-do, Korea, Republic of; Hyun Jung Kim, Jin Won Kim, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Kyeongsoon Park, Chung-Ang Univ, Gyeonggi-do

12:30 PM

Board # 1111

Fibrocystin and Polycystin Are Determinants of Endothelial Cells Phenotype and Function

Federico Franchi, Karen Peterson, Ezequiel Tolosa, Maria Valentina Irazabal, Vicente Torres, Peter C Harris, Martin E Fernandez-Zapico, **Martin G Rodriguez-Porcel** , Mayo Clinic, Rochester, MN

12:30 PM

Board # 1112

Prokineticin Receptor-2 Orchestrates Cardiomyocyte-endothelial Cell Communications via Cardiomyocyte Secretoms

**Canan G Nebigil** , CNRS, Illkirch, France; Kyoji Urayama, Advanced Telecommunications Res Inst Intl, Kyoto, Japan; Ferda Demir, Anais Audebrand, CNRS, Illkirch, France; Marja Steenman, L'institut du thorax INSERM UMR 1087 / CNRS UMR 6291, NANTES CEDEX 1, France

# Abstract Poster Session

## CA.APS.03 - Stem Cells

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 1076

Cardiac Mesenchymal Cells May Not Repair Hearts Subjected To Non-reperfused Infarction

**Sujith Dassanayaka** , Andrea Jurkovic, Kenneth Brittian, Marjan Nasr, Yi Wei Zheng, Timothy Ndagi Audam, Marcin Wysoczynski, Steven P Jones, Univ of Louisville, Louisville, KY

12:30 PM

Board # 1078

Transient Natural Cardiac Regeneration in a Novel Neonatal Rat Myocardial Infarction Model

**Hanjay Wang** , Michael J Paulsen, Camille E Hironaka, Justin M Farry, Akshara D Thakore, Haley J Lucian, Anahita Eskandari, Shreya Anilkumar, Hye Sook Shin, Frederick Grady, Frank J Buncom, Matthew A Wu, Annabel M Imbrie-Moore, Lyndsay M Stapleton, Amanda N Steele, Y. Joseph Woo, Stanford Univ, Stanford, CA

12:30 PM

Board # 1079

Cardiac Atrial Appendage Stem Cells Transplantation Prevents Cellular Remodeling After MI in Rats

**Lize Evens** , Hanne Beliën, Dorien Deluyker, UHasselt - Biomed, Hasselt, Belgium; Maxim Verboven, UHasselt, Hasselt, Belgium; Jean-Luc Rummens, UHasselt/Jessa Hosp, Hasselt, Belgium; Marc JH Hendrikx, Heart Ctr Isala Klinieken Zwolle, Zwolle, Netherlands; Virginie Bito, Hasselt Univ, hasselt, Belgium

12:30 PM

Board # 1080

High Mobility Group Box 1 Induced Endogenous Bone Marrow Mesenchymal Stem Cells Have Potential to Improve Cardiac Function by Inhibition of Ventricular Remodeling After Myocardial Infarction

**Takasumi Goto** , Osaka Univ Graduate Sch of Med, Suita City, Osaka, Japan; Shigeru Miyagawa, Osaka Univ Graduate Sch of Med, Suita city, Osaka, Japan; Katsuto Tamai, Osaka Univ Graduate Sch of Med, Suita City, Osaka, Japan; Takuji Kawamura, Ryohei Matsuura, Akima Harada, Yoshiki Sawa, Osaka Univ Graduate Sch of Med, Suita city, Osaka, Japan

12:30 PM

Board # 1081

Crispr-based Activation of Endogenous Loci Enables Conversion of Mouse Fibroblasts Into Cardiac Progenitor Cells for Myocardial Infarction Treatment

**Jialiang Liang** , Lin Jiang, Wei Huang, Univ of Cincinnati, Cincinnati, OH; Yigang Wang, Univ of Cincinnati, cincinnati, OH

12:30 PM

Board # 1082

Histological Analysis of Cytokine/Extra Cellular Matrix-related Angiogenic Process Induced by Cell Sheet Therapy in a Rat Chronic Myocardial Infarction Model

**Akima HARADA** , Shigeru Miyagawa, Satoshi Kainuma, Yoshiki Sawa, Osaka Univ, Osaka, Japan

12:30 PM

Board # 1083

Characterization of Cardiac Mesenchymal Cells From Non-Failing and Failing Hearts

**Timothy Ndagi Audam** , Andra Jurkovic, Bethany W Long, Yi Wei Zheng, Lauren Higgins, Univ of Louisville, Louisville, KY; Tyler Weirick, Cardiovascular Innovation Inst, Louisville, KY; Shizuka Uchida, Marcin Wysoczynski, Steven P Jones, Univ of Louisville, Louisville, KY

12:30 PM

Board # 1084

Molecular Transferring of Anti-Angiogenic and Pro-Apoptotic Signaling From Diabetic CD34+ Cells to the Vascular Endothelium via Activation of the microRNA-21/PDCD4 Pathway

**Gaia Spinetti** , Elena Sangalli, Davide Maselli, Rosa Vono, Ornella Colpani, Elena Tagliabue, IRCCS MultiMedica, Milan, Italy; David Ferland-McCollough, Univ of Bristol, Bristol, United Kingdom; Franco Carnelli, Patrizia Orlando, IRCCS MultiMedica, Milan, Italy; Luisa Sambado, Ospedale Santa Maria di Ca' Foncello, Treviso, Italy; Maria Sambataro, Santa Maria di Ca'Foncello Hosp, Treviso, Italy; Paolo R Madeddu, Univ Bristol, Bristol, United Kingdom

# Abstract Poster Session

## IN.APS.06 - Structural Interventions in 2019

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4127

Geriatric Nutritional Risk Index in Patients Undergoing Transcatheter Aortic Valve Replacement

Hatim Seoudy, Johanne Frank, Univ Hosp Schleswig-Holstein, Kiel, Germany; Baravan Al-Kassou, Jasmin Shamekhi, Atsushi Sugiura, Eberhard Grube, Univ Hosp Bonn, Bonn, Germany; Georg Lutter, Christian Kuhn, Univ Hosp Schleswig-Holstein, Kiel, Germany; Hendrik Treede, Georg Nickenig, Univ Hosp Bonn, Bonn, Germany; Norbert Frey, Univ Hosp Schleswig-Holstein, Kiel, Germany; Jan-Malte Sinning, Univ Hosp Bonn, Bonn, Germany; **Derk Frank** , Univ Hosp Schleswig-Holstein, Kiel, Germany

12:30 PM

Board # 4128

Impact of Extent of Coronary Revascularization on Mortality After Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis

**Muhammad Junaid Ahsan** , Noman Lateef, Creighton Univ, Omaha, NE; Saad Ullah Malik, Univ of Arizona, Tucson, AZ; Muhammad Fazeel Anwar, Creighton Univ, omaha, NE; Hafiz Muhammad Z Zubair, Sisters of Charity Hosp, Buffalo, NY; Azka Latif, Mohsin Mansoor Mirza, Mark J Holmberg, Creighton Univ, Omaha, NE

12:30 PM

Board # 4129

Comparison of Clinical Outcome Between Noncontrast Transcatheter Aortic Valve Replacement With Conventional Transcatheter Aortic Valve Replacement in Patients With Renal Insufficiency

**Jah Yeon Choi** , Korea Univ Guro Hosp, Seoul, Korea, Republic of; Chi Young Shim, Yonsei Univ Coll of Med, Seoul; Young-Guk Ko, Yonsei Cardiovascular Ctr, Seoul, Korea, Republic of; Geu-Ru Hong, Yonsei Univ, Seoul; Myeong-Ki Hong, Severance Cardiovascular Hosp, Seoul

12:30 PM

Board # 4130

Change in Hospitalization Rates Following Transcatheter Mitral Valve Repair: A Nationwide Cohort Sample

**Ahmed Elkaryoni** , Univ of Missouri-Kansas City, Kansas City, MO; Adnan K Chhatriwalla, Kevin F Kennedy, John T Saxon, David J Cohen, Suzanne V Arnold, Saint Luke's Hosp / Mid America Heart Inst, Kansas City, MO

12:30 PM

Board # 4131

Safety and Clinical Effectiveness of Left Atrial Appendage Occlusion in Patients With Chronic Kidney Disease

**Domenico Giovanni Della Rocca** , St. David's Medical Ctr, Austin, TX; Rodney Paul Horton, TCAI, Austin, TX; Gaetano Fassini, Monzino Hosp, Milan, Italy; Luigi Di Biase Sr., Albert Einstein Coll of Med, New York, NY; Sanghamitra Mohanty, St. Davids Medical Ctr, Austin, TX; Chintan Gautambhai Trivedi, TCAI, Austin, TX; Alessio Gasperetti, Monzino Hosp, Milan, Italy; Veronica Natale, TCAI, Austin, TX; Mohamed Ahmed Bassiouny, Cleveland Clinic Fndn, Cleveland, OH; Joe Gallinghouse, TCAI, Austin, TX; Jorge Romero, Montefiore Albert Einstein, Bronx, NY; Amin Al-ahmad, Texas Cardiac Arrhythmia Inst, Austin, TX; David Burkhardt, TCAI, Austin, TX; Claudio Tondo, St.Ambrogio's Clinical Inst,Un, Milan, Italy; Andrea Natale, Texas Cardiac Arrhythmia, Austin, TX

12:30 PM

Board # 4132

Incidence Of Atrial Fibrillation In Patients Treated With Transcatherter Versus Surgical Aortic Valve Replacement In Low Risk Patients: A Meta-analysis

**Jay Shah** , Mercy St. Vincent Medical Ctr, Toledo, OH; Ashish Kumar, Saint John's Medical Coll Hosp, Bangalore, India; Samarthkumar Jayeshkumar Thakkar, Rochester General Hosp, Rochester, NY; Muhammad Khan, Mercy St. Vincent Medical Ctr, Toledo, OH; Nageshwara Gullapalli, Univ of Nevada Reno Sch of Med, Reno, NV; Perwaiz M Meraj, North Shore Univ Hosp, Manhasset, NY; Rajkumar Prakashbhai Doshi, Univ of Nevada Reno SOM, Reno, NV

12:30 PM

Board # 4133

TAVR in Patients With Dialysis- The Next Frontier? Readmission Rates and Mortality Differences in Comparison to SAVR- A Nationwide Analysis

**Aaqib H Malik** , Westchester Medical Ctr, Valhalla, NY; Srikanth Yandrapalli, Westchester Medical Ctr, White Plains, NY; Syed Zaid, Westchester Medical Ctr, Valhalla, NY; Suchith Shetty, Univ of Iowa, Iowa City, IA; Senada Malik, Univ of New England, Portland, ME; Wilbert S Aronow, New York Medical Coll, New Rochelle, NY; Cenap Undemir, Hasan Ahmad, Westchester Medical Ctr, Valhalla, NY

12:30 PM

Board # 4134

Outcomes of Patients With Bicuspid Aortic Valves Undergoing Transcatheter Aortic Valve Implantation Stratified by Valve Type Used

**Raymundo Alain Quintana Quezada** , Emory Univ, Atlanta, GA; Dominique Monlezun, Univ of Texas at Houston, Houston, TX; Giovanni Davogustto, Vanderbilt Univ, Nashville, TN; Humberto R Saenz, Univ of California San Diego, San Diego, CA; Diego Lugo Baruqui, Mount Sinai Medical Ctr, Miami, FL; Ali Denktas, Baylor Coll of Med, Houston, TX; Hani Jneid, David Paniagua, Baylor Coll of Med and Michael E. DeBakey VA Medical Ctr, Houston, TX

12:30 PM

Board # 4135

Vascular Access and Closure Management in Patients With Severe and Morbid Obesity Undergoing Transcatheter Aortic Valve Replacement

**Jose Tafur Soto** , Ochsner Clinic Fndn, New Orleans, LA; Natalia Giraldo, Univ ICESI / Fundacion Clinica Valle del Lili, Cali, Colombia; Michael Bates, Patrick E Parrino, Stephen R Ramee, Ochsner Clinic Fndn, New Orleans, LA

12:30 PM

Poster Professor

Tarek Helmy, St. Louis, MO

# Abstract Poster Session

## SA.APS.06 - Surgical Revascularization for Ischemic Heart Disease

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4263

Obstructive Sleep Apnea and Diabetes Independently Increase Risk of Cardiovascular Events After Coronary Artery Bypass Grafting

**Aye Thandar Aung** , Chieh Yang Koo, Zhengfeng Chen, Natl Univ Heart Ctr, Singapore, Singapore; William Kristanto, Ng Teng Fong General Hosp, Singapore, Singapore; Hui Wen Sim, Natl Univ Heart Ctr, Singapore, Singapore; Wilson W. Tam, Natl Univ of Singapore, Singapore, Singapore; Carlo Francisco Gochuico, Kent Tan, Giap-Swee Kang, Sorokin Vitaly, Natl Univ Heart Ctr, Singapore, Singapore; Paul Ong, Tan Tock Seng Hosp, Singapore, Singapore; Pipin Kojodjojo, A Mark Richards, Huay-Cheem Tan, Theodoros Kofidis, Chi-Hang Lee, Natl Univ Heart Ctr, Singapore, Singapore

12:30 PM

Board # 4264

Impact of In-Situ Right Internal Thoracic Artery Grafting via the Transverse Sinus on Long-Term Outcomes After Coronary Artery Bypass Grafting

**Keisuke Hakamada** , Kokura Memorial Hosp, Kitakyushu City Fukuoka, Japan

12:30 PM

Board # 4265

Long-term Mortality and Readmissions Following Isolated Reoperative Coronary Artery Bypass Grafting: A Propensity Matched Analysis

**Valentino Bianco** , Arman Kilic, Univ of Pittsburgh, Pittsburgh, PA; Thomas G Gleason, UPMC Shadyside, Pittsburgh, PA; Forozan Navid, Ibrahim Sultan, Univ of Pittsburgh, Pittsburgh, PA

12:30 PM

Board # 4266

Preoperative Aspirin in Coronary Artery Bypass Grafting: A Retrospective Analysis of 45666 Cases From Nationwide Japanese Surgical Database

**Hiraku Kumamaru** , Univ of Tokyo, Tokyo, Japan; Shun Kohsaka, Keio Univ, Tokyo, Japan; Hiroaki Miyata, Univ of Tokyo, Tokyo, Japan; Aya Saito, Noboru Motomura, Toho Univ, Chiba, Japan

12:30 PM

Board # 4267

Three Months of Dual Antiplatelet Therapy is Optimal Time for Mortality and Morbidity Benefit Post Coronary Artery Bypass Grafting - Results of an In-depth, Retrospective Review of a Large Series of Patients From a Single Center

**Iftikhar Ali Ch** , Ahmad Usmani, Pei-Tzu Wu, Raja Ullah, Abdul Qadar, Mashal Tahirkheli, Hunter Weitzel, Alexander Harvey, Rahat Jamal, South Oklahoma Heart Res, Oklahoma City, OK; Zeshan Malik, South Oklahoma Heart Res, Edmond, OK; Muhammad Ahzam, South Oklahoma Heart Res, Oklahoma City, OK; Faisal Latif, Oklahoma Univ Health Science Ctr, Oklahoma City, OK; Jeffrey Garret, Micheal Cannon, Steven Miller, South Oklahoma Heart Res, Oklahoma City, OK; Naeem K Tahirkheli, Oklahoma Heart Hosp, Oklahoma City, OK

12:30 PM

Board # 4269

Dual Antiplatelet Therapy is Not Associated With Better Early-Term Outcomes After Coronary Artery Bypass Grafting

**Jianyu Qu** , Heng Zhang, Chenfei Rao, Hanping Ma, Zhe Zheng, Fuwai Hosp, Chinese Acad of Medical Sciences and Peking Union Medical Coll, Beijing, China

12:30 PM

Board # 4270

Impact of Revascularization Strategy on Left Ventricular Ejection Fraction (LVEF) Recovery in Patients With Coronary Artery Disease (CAD) and Severely Reduced Ejection Fraction

**Nadia Clarizia** , Marc Ruel, Alex Nantsios, Dylan Demarco, Univ of Ottawa Heart Inst, Ottawa, ON, Canada; Benjamin M Hibbert, Univ of Ottawa Heart Inst, Manotick, ON, Canada; Louise Sun, Univ of Ottawa Heart Inst, Ottawa, ON, Canada

12:30 PM

Board # 4271

Does Extended Multiarterial Grafting Incrementally Improve Long Term Survival After Coronary Surgery?

**Alistair Royse** , Staurt Boggett, Rinaldo Bellomo, Sandy Clarke-Errey, The Univ of Melbourne, Melbourne, Australia; Zulfayandi Pawanis, Univs Airlangga, Mataram, Indonesia; Christopher Reid, Curtin Univ, Perth, Australia; Colin Royse, The Univ of Melbourne, Melbourne, Australia

12:30 PM

Board # 4272

Feasibility And Safety Of Total Arterial Revascularization In Consecutive, Unselected Coronary Artery Bypass Grafting Patients Aged 70 Years And Under

**Pierre Voisine** , IUCPQ, Quebec, QC, Canada; Juan Grau, Univ of Ottawa Heart Inst, Ottawa, ON, Canada; David Glineur, Ottawa Heart Inst, Ottawa, ON, Canada

# Abstract Poster Session

## HF.APS.19 - The Kidney in Heart Failure

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2261

Diuretic Efficiency is Higher for Black Subjects Enrolled in Acute Decompensated Heart Failure Trials

**Alanna A Morris** , Emory Univ Sch Med, Atlanta, GA; Aditi Nayak, Emory Univ, Atlanta, GA; Yi-An Ko, Emory Univ Sch Med, Atlanta, GA; Michael Felker, Duke Clinical Res Inst, Durham, NC; Margaret M Redfield, Mayo Clinic, Rochester, MN; Jeffrey M Testani, Yale, Guilford, CT; Javed Butler, Emory, Atlanta, GA

12:30 PM

Board # 2262

The Impact of Worsening Renal Function on Long-Term Clinical Outcome in Patients With Acute Decompensated Heart Failure Treated With Tolvaptan

**Takayuki Nagai** , Daisuke Kinoshita, Hiromasa Hasegawa, Shintaro Sasaki, Hyuma Daidoji, Katsuaki Takahashi, Yoshiaki Tamada, Akio Fukui, Tomoyasu Yahagi, Motoyuki Matsui, Yamagata Prefectural Central Hosp, Yamagata, Japan

12:30 PM

Board # 2263

Heart Failure and Chronic Kidney Disease in Patients Undergoing Non-Cardiac Surgery

**Boyangzi Li** , NYU Langone Health, New York, NY; Tanya Wilcox, NYU Langone Health,, New York, NY; Nathaniel Smilowitz, NYU Sch of Med, New York, NY; Jonathan D Newman, New York Univ Medical Ctr, New York, NY; Jeffrey S Berger, New York Univ Sch Med, New York, NY

12:30 PM

Board # 2265

Incidence of Hyperkalemia in a Referral Center for Latin-American Cardiology: It is Time for New Therapies

**Sebastian Gallo-Bernal** , Isabel Hernandez-Linares, Maria Juliana Rodriguez, Fundacion Cardioinfantil, Bogota, Colombia

12:30 PM

Board # 2266

The Prognostic Value of Serum Bicarbonate Levels in Critically Ill Patients With Acute Pulmonary Edema

**Junichi Imanishi** , Naoya Kuwahara, Sachiyo Yoneda, Kazuhiko Nakayama, Shinko Hosp, Kobe-city, Japan; Tomoyuki Honjo, Shinko Hosp, Kobe, Japan; Kohei Kamemura, Kenji Kaihotsu, Masanori Iwahashi, Shinko Hosp, Kobe-city, Japan

12:30 PM

Board # 2267

Rethink That Tap - Paracentesis in Patients With Ascites and Systolic Heart Failure is Not Associated With Improve Renal Function or Reduction in All-Cause Mortality

**Yuxiang Wang** , Wayne L Miller, Mayo Clinic, Rochester, MN

# Abstract Poster Session

## SA.APS.05 - Thoracic Aortic Surgery/Disease I

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4253

Wall Stress of Ascending Thoracic Aortic Aneurysm versus Normal Aorta: Towards Defining Wall-stress Based Thresholds for Aneurysm Intervention

**Andrew D Wisneski** , Univ of CA, San Francisco, CA; Zhongjie Wang, UCSF, San Francisco, CA; Yue Xuan, Univ of California San Francisco, San Francisco, CA; Matthew Lum, Kaushik Kondubhatla, Univ of CA, San Francisco, CA; Michael D Hope, SFVAHCS, UCSF, San Francisco, CA; David Saloner, Univ of California San Francisco, San Francisco, CA; Julius Guccione, UCSF, San Francisco, CA; Liang Ge, Univ of CA, San Francisco, CA; Elaine E Tseng, UCSF, San Francisco, CA

12:30 PM

Board # 4254

Perioperative and Late Outcomes After Thoracic Aortic Replacement for Giant Cell Aortitis: A Canadian Thoracic Aorta Collaborative Experience

**Charles Laurin** , Laval Univ, Quebec, QC, Canada; Peter Thin Vo, Ottawa Univ, Ottawa, ON, Canada; Vincent Chauvette, Univ of Montreal, Montreal, QC, Canada; Ismail El-Hamamsy, Montreal Heart Instiute, Montreal, QC, Canada; Munir Boodhwani, Univ Ottowa Heart Inst, Ottawa, ON, Canada; Francois Dagenais, Laval Hosp, Quebec, QC, Canada

12:30 PM

Board # 4255

Biomechanical and Histological Analysis Supports Increased Stiffness and Fibrosis in Chronic versus Acute Aortic Dissection Flaps

**Xiaoying Lou** , Emory Univ Sch of Med, Atlanta, GA; Wei Sun, Minliang Liu, Fatiesa Sulejmani, Qing Zou, Muhammed Subhi AL Jabi, Georgia Inst of Technology, Atlanta, GA; Edward P Chen, Bradley G Leshnower, Emory Univ Sch of Med, Atlanta, GA

12:30 PM

Board # 4256

Establishment of Specific Risk Models for Thoracoabdominal Aortic Aneurysm Repair : A Nationwide Analysis Based on the Japan Cardiovascular Surgery Database

**Yoshikatsu Saiki** , Tohoku university Graduate Sch of Med, Sendai, Japan; Hiroyuki Yamamoto, Graduate Sch of Med,The Univ of Tokyo, Tokyo, Japan; Hiroaki Miyata, Keio Univ Sch of Med, Tokyo, Japan; Noboru Motomura, Toho Univ Medical Ctr, Sakura, Japan; Yukihiro Hayatsu, Konosuke Sasaki, Tohoku university Graduate Sch of Med, Sendai, Japan; Shinichi Takamoto, Keio Univ Sch of Med, Tokyo, Japan

12:30 PM

Board # 4257

Wall Stress Comparison in Genetic Aortopathies

**Abraham J Rizkalla** , Royal Prince Alfred Hosp, Sydney, Australia; Rajesh Puranik, Royal Prince Alfred Hosp, Camperdown, Australia; Richmond W Jeremy, Univ of Sydney, Sydney, Australia

12:30 PM

Board # 4258

Long-term Outcome of Immediate Aortic Repair for Acute Type a Aortic Dissection Complicated by Coma

**Chikashi Nakai** , So Izumi, Japanese Red Cross Kobe Hosp, Kobe, Japan; Shinichi Nakayama, Hyogo Emergency Meical Ctr, Kobe, Japan; Takuro Tsukube, Japanese Red Cross Kobe Hosp, Kobe, Japan

12:30 PM

Board # 4259

Deletion of Vascular P53 Promotes Pathologies in Aortic Dissection

**Ayako Nagasawa** , Ippei Shimizu, Yohko Yoshida, Masanori Tsuchida, Tohru Minamino, Nigata Univ, Niigata, Japan

12:30 PM

Board # 4260

Receptor for Advanced Glycation End-Products Antagonist Peptide Restores Angiotensin 2-Mediated Ascending Aortic Wall Remodeling In Enos -/- Mice

**Chiara Camillo** , Yingfei Xue, Columbia Univ, New York, NY; Ian Roberts, Univ of Pennsylvania, Philadelphia, PA; Kiera Robinson, Columbia Univ, New York, NY; Richard Kenneth Assoian, Univ of Pennsylvania, Philadelphia, PA; Hiroo Takayama, Giovanni Ferrari, Columbia Univ, New York, NY

12:30 PM

Board # 4261

Differential DNA Methylation in Marfan Syndrome is Associated With Inflammation and Cardiac Contraction

**Cassandra Malecki** , Elizabeth N Robertson, Kiersten A Liddy, Alex Sahagian, Callum Gover, Yaxin Lu, Murat Kekic, Donna Lai, Brett D Hambly, Richmond W Jeremy, Univ Sydney, Sydney, Australia

12:30 PM

Board # 4262

Outcomes of Surgical Intervention for Acute Type A Aortic Dissection in Octogenarians - Insights From the International Registry of Acute Aortic Dissection (IRAD)

**Stevan S Pupovac** , Jonathan Hemli, Northwell Health, New York, NY; Thomas G Gleason, UPMC Shadyside, Pittsburgh, PA; Thoralf M Sundt II, Mass General Hosp, Boston, MA; Nimesh D Desai, Univ Pennsylvania, Philadelphia, PA; Davide Pacini, Univ Hosp S. Orsola, via Massarenti 9, Italy; Maral Ouzounian, Toronto General Hosp, Toronto, ON, Canada; Jehangir J Appoo, Univ of Calgary Medical Ctr, Calgary, AB, Canada; Daniel G Montgomery, Kim Eagle, Univ of Michigan, Ann Arbor, MI; Takeyoshi Ota, The Univ of Chicago, Chicago, IL; Marco Di Eusanio, Univ di Bologna, Ancona, Italy; Anthony L Estrera, UT Medical Sch Houston, Houston, TX; Joseph S Coselli, Baylor Coll of Med, Houston, TX; Himanshu J Patel, Univ Michigan Health System, Ann Arbor, MI; Santi Trimarchi, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy; Derek Ralph Brinster, Northwell Health System, New York, NY

12:30 PM

Poster Professor

Bo Yang, Ann Arbor, MI

# Abstract Poster Session

## NR.APS.03 - Transitions of Care Across Settings

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4241

Group-based Trajectories of Blood Pressure During Admission Can Predict the Risk of In-hospital Death in Patients With Acute Heart Failure

**Tsuey-Yuan Huang** , Ming-Fen Tsai, Chang Gung Univ of Science and Technology, Taoyuan, Taiwan

12:30 PM

Board # 4242

Change in Caregiver Burden From Before to Early After Surgery: Findings From the Sustaining Quality of Life of the Aged: Transplant or Mechanical Support (SUSTAIN-IT) Study

**Kathleen L Grady** , Adin-Cristian Andrei, Yao Xu, Northwestern Univ, Chicago, IL; Michael G Petty, Univ of Minn Med Ctr, Richfield, MN; Andrew Kao, St. Luke's Mid America Heart Inst, Kansas City, MO; Eileen M Hsich, Cleveland Clinic Fndn, Cleveland, OH; Mary Amanda Dew, Univ of Pittsburgh, Pittsburgh, PA; Robert L Kormos, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Duc Thinh Pham, Northwestern Memorial Hosp, Chicago, IL; Shane LaRue, Washington Univ, St. Louis, MO; William Cotts, Advocate Christ Medical Ctr, Oak Lawn, IL; Salpy V Pamboukian, Univ of Alabama at Birmingham, Birmingham, AL; Francis D Pagani, Univ Michigan Cardiovasc Ctr, Ann Arbor, MI; Brent Lampert, Ohio State Univ, Columbus, OH; Maryl R Johnson, Univ Wisconsin Madison, Madison, WI; Margaret A Murray, Univ of Wisconsin Hosp, Madison, WI; Takeda Koji, Columbia Univ, New York, NY; Melana Yuzefpolskaya, Columbia Univ Medical Ctr, New York, NY; Scott C Silvestry, Florida Hosp, Orlando, FL; John A. Spertus, Mid America Heart Inst, Kansas City, MO; James K. Kirklin, Univ of Alabama at Birmingham, Birmingham, AL; S. Craig Collum, Univ of Alabama, Birmingham, AL; Clyde W Yancy, Northwestern Univ, Chicago, IL

12:30 PM

Board # 4243

Patients' Perceptions of Generic Drugs After Percutaneous Coronary Intervention: A Multicentre Cohort Study

**Trond Røed Pettersen** , Jan Schjott, Haukeland Univ Hosp, Bergen, Norway; Heather Allore, Yale Sch of Med, New Haven, CT; Bjørn Bendz, Oslo Univ Hosp, Rikshospitalet, Oslo, Norway; Bengt Fridlund, Linnaeus Univ, Växjö, Sweden; Alf Inge Larsen, Jan Erik Nordrehaug, Stavanger Univ Hosp, Stavanger, Norway; Svein Rotevatn, Tore Wentzel-Larsen, Tone M Norekvål, Haukeland Univ Hosp, Bergen, Norway; On behalf of the CONCARD Investigators

12:30 PM

Board # 4244

Depressive Symptom Subgroups and Their Association With Incident Cardiovascular Risk Factors in the Coronary Artery Risk Development in Young Adults (CARDIA) Study

**Diana Chirinos** , Kiarri N Kershaw, Norrina B Allen, Northwestern Univ, Chicago, IL; Allison J Carroll, Northwestern Univ Feinberg Sc, Chicago, IL; Tene T Lewis, Emory Univ, Atlanta, GA; Pamela Schreiner, Univ of Minnesota, Minneapolis, MN; Cora E Lewis, Univ of Alabama Birmingham, Birmingham, AL; Catarina I. Kiefe, Univ of Massachusetts Medical Sch, Sterling, MA; Mercedes R Carnethon, Northwestern Univ, Chicago, IL

12:30 PM

Board # 4245

Underuse of Evidence-Based Guidelines for Incident Type 2 Diabetes in a Countywide Cohort: Outcomes Across Socioeconomic Strata at One Year

**Bradi B Granger** , Duke Univ Sch of Nursing, Durham, NC; Susan E Spratt, Matthew Phelan, Ursula Rogers, Benjamin A Goldstein, Duke Univ, Durham, NC

12:30 PM

Board # 4246

Evaluation of a Comprehensive Nutrition Pathway for Infants Requiring Neonatal Cardiac Surgery

**Amy Jo Lisanti** , Melanie Savoca, Children's Hosp of Philadelphia, Philadelphia, PA; Sharon Irving, Univ of Pennsylvania, Philadelphia; Jodi Chen, Childrens Hosp Philadelphia, Philadelphia, PA; Chitra Ravishankar, Childrens Hosp of Philadelphia, Philadelphia, PA; Maria Mascarenhas, Erin Sullivan, Children's Hosp of Philadelphia, Philadelphia, PA; Andrew Costarino, Children's Hosp of Philadelphia, Philadelphia; Barbara Medoff-Cooper, Univ of Pennsylvania, Philadelphia, PA; Jungwon Min, CHOP, Huntingdon Vy, PA; Antara Mondal, Jing Huang, James W Gaynor, Children's Hosp of Philadelphia, Philadelphia, PA

12:30 PM

Board # 4247

Evaluation of a Tummy Time Intervention to Improve Motor Skill Development in Infants After Cardiac Surgery

**Karen Uzark** , Cynthia Smith, Sunkyung Yu, Ray Lowery, Chris Tapley, Jennifer Romano, Univ of MI Mott Children's Hosp, Ann Arbor, MI; Jennifer Butcher, Univ of Michigan CS Mott Children's Hosp, Ann Arbor, MI

12:30 PM

Board # 4248

Effects of an Intervention on Physical Activity, Body Mass Index, Percent Body Fat, and Cardiorespiratory Fitness Among 5th- 8thgrade Girls With Body Mass Index Z-Score Greater Than or Equal to 0

**Lorraine B Robbins** , Fujun Wen, Jiying Ling, Michigan State Univ, East Lansing, MI

12:30 PM

Poster Professor

Mariann R Piano, Nashville, TN

12:30 PM

Board # 4249

Nightmares and Cardiovascular Disease Risk Behaviors Among Young Adults

**William E Kelly** , California State Univ, Bakersfield, Bakersfield, CA; Qiujun Yu, Univ of Iowa Hosp, Iowa City, IA

12:30 PM

Board # 4250

Supplemental Oxygen is Associated With Larger Infarct Size but Not Excess Risk of Adverse Cardiac Events in Non-st Elevation Myocardial Infarction

**Omar Abu-Jaradeh** , Brown Univ / Kent Hosp, Warwick, RI; Abdullah Ahmad, Stephanie O Frisch, Univ of Pittsburgh, Pittsburgh, PA; Ziad Faramand, Univ of Pittsburgh Medical Ce, Pittsburgh, PA; Parker Landis, Ahmad Mahmoud, Clifton W Callaway, Christian Martin-Gill, Salah S Al-Zaiti, Univ of Pittsburgh, Pittsburgh, PA

12:30 PM

Board # 4251

Ecg Characteristics Associated With Complications After Intervention Among UA/NSTEMI Patients With Transient Myocardial Ischemia

**Dillon J. Dzikowicz** , Mary Carey, Univ of Rochester, Rochester, NY; Michele M Pelter, UCSF, San Francisco, CA

12:30 PM

Board # 4252

Shortness of Breath, Chest Pain, and Level of Consciousness Predict Multiple EMS Transports Across 8 Years Among Community Dwelling Adults With Self-Reported Heart Failure

**Susan J Pressler** , Miyeon Jung, Indiana Univ Sch of Nursing, Indianapolis, IN; Christopher S Lee, Boston Coll, Chestnut Hill, MA; Thomas P Arkins, Indianapolis Emergency Medical Services, Indianapolis, IN; Daniel O'Donnell, Giorgos Bakoyannis, Indiana Univ Sch of Med, Indianapolis, IN; Robin Newhouse, Indiana Univ Sch of Nursing, Indianapolis, IN; Irmina Gradus-Pizlo, Univ of California Irvine Sch of Med, Orange, CA; Peter Pang, Indiana Univ Sch of Med, Indianapolis, IN

# Abstract Poster Session

## CH.APS.11 - Treatments and Outcomes in Congenital Heart Disease

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 4022

Cardiac Asynchrony and the Efficacy of Radiofrequency Ablation in Children With Type B Pre-Excitation Syndrome Induced Left Ventricular Dysfunction

**Sun Yan** , Beijing Children's Hosp, Beijing, China

12:30 PM

Board # 4023

Invasive Hemodynamic Assessment is Less Reflective of the Awake State Under Inhaled Volatile Versus Intravenous Anesthesia in Pediatric Patients

**Steven J Healan** , Genevieve E Staudt, George T Nicholson, Dana R Janssen, Vanderbilt Univ Medical Ctr, Nashville, TN; Thomas P Doyle, Vanderbilt Univ Medical Ctr, Nashvile, TN; Heidi A Smith, Nathan E Hill, Fred S Lamb, Vanderbilt Univ Medical Ctr, Nashville, TN

12:30 PM

Board # 4024

Safety and Efficacy of Amlodipine in Children Less Than One Year of Age in the Cardiovascular Intensive Care Unit

**Alex J Foy** , Samantha K Byrum, Children's Health Dallas, Dallas, TX; Catherine M Ikemba, Jessica E Pruszynski, Timothy Pirolli, Susan R Hupp, Joshua S Wolovits, UT Southwestern, Dallas, TX

12:30 PM

Board # 4025

Burden of Respiratory Syncytial Virus in Children With Congenital Heart Disease

**Murad Almasri** , Univ of Texas Medical Branch, Galveson, TX; Hasan F. Othman, Cleveland Clinic Children's, Cleveland, OH; Mohammed Hamzah, Cleveland clinic, Cleveland, OH

12:30 PM

Board # 4026

Outcomes of Neonates With Hypoplastic Left Heart Syndrome: A Comparative Analysis Between Two Chronological Groups (1998-2006 Versus 2007-2014) Using the National Inpatient Sample Database

**Hasan F. Othman** , Cleveland Clinic Children's, Cleveland, OH; Mohammed Hamzah, Cleveland Clinic, Cleveland, OH; Hany Aly, Cleveland Clinic Children's, Cleveland, OH

12:30 PM

Board # 4027

Predictive Modeling for ADHD in Adolescents With Critical Congenital Heart Disease

**Amara Majeed** , David Wypij, Valerie Rofeberg, David Bellinger, Boston Children's Hosp, Boston, MA; Jane Newburger, Boston Children's Hosp, Boston, MA

12:30 PM

Board # 4028

Comparison of Serum Biomarkers of Myocardial Fibrosis With Cardiac Magnetic Resonance in Patients Operated for Tetralogy of Fallot

Michael Dilorenzo, Columbia Univ Medical Ctr, New York, NY; **Grace DeCost** , Children's Hosp of Philadelphia, Philadelphia, PA; Francis X McGowan, Mark Alan Fogel, Elizabeth Goldmuntz, Laura Mercer-Rosa, Childrens Hosp of Philadelphia, Philadelphia, PA

12:30 PM

Board # 4030

Association Between Intravenous Acetaminophen and Opioid Use in Postoperative Management of Patients Following Congenital Heart Defect Repair

Olga Rodriguez, Lauren Jenkins, Cook Children's Medical Ctr, Fort Worth, TX; Fadeke Ogunyankin, Cook Children's Medical Ctr, Burleson, TX; Jay Duncan, **Lane Lanier** , Cook Children's Medical Ctr, Fort Worth, TX

# Abstract Poster Session

## EA.APS.08 - What's New in Pacing?

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 2000

The Strength Duration Curve in His Bundle Pacing: Implications for Device Longevity

**Amrish Deshmukh** , Univ of Michigan, Ann Arbor, MI; Timothy Betchol, Abbot, Williamsport, PA; Kelly Brown, Pramod Deshmukh, Guthrie Clinic, Sayre, PA

12:30 PM

Board # 2001

Is There a Difference Between Selective and Non-Selective His Bundle Pacing? An Epicardial Mapping Study

**Annie M Hirahara** , Matthias Lange, Univ of Utah, Salt Lake City, UT; Kennosuke Yamashita, Univ of Utah, Salt Lake Cty, UT; Ravi Ranjan, Univ Utah Hosp, Salt Lake Cty, UT; Muhammad Shuja Khan, The Univ of Utah, Salt Lake City, UT; Ankur Shah, Derek J Dosdall, Univ of Utah, Salt Lake City, UT

12:30 PM

Board # 2002

Both Selective and Nonselective His Bundle, but Not Myocardial Pacing, Preserve Ventricular Electrical Synchrony

**Karol Curila** , Radka Prochazkova, Petr Stros, Jana Vesela, Cardiocenter of 3-rd Faculty of Med, Prague, Czech Republic; Pavel P Osmancik, Cardiocenter, 3rd Medical Sch, Charles Univ and Univ Hosp Kralovske Vinohrady Pra, Prague, Czech Republic; Marek Jastrzebski, Pawel Moskal, Jagiellonian Univ Medical Coll, Krakow, Poland; Josef Halamek, Pavel Jurak, Czech Acad of Sciences, Brno, Czech Republic; Petr Widimsky, Cardiocentre, Praha 10, Czech Republic

12:30 PM

Board # 2003

His-Bundle Pacing Improves Tricuspid Regurgitation in Patients With Bradyarrhythmia

**Hannah E Wey** , Univ of Chicago Med, Chicago, IL; Parth V Desai, Cook County Hosp, Chicago, IL; Jonathan Lattell, Andrew Beaser, Zaid A Aziz, Hemal Nayak, Univ of Chicago Med, Chicago, IL; Roderick Tung, Univ of Chicago, Chicago, IL; Gaurav A Upadhyay, The Univ of Chicago Med, Chicago, IL

12:30 PM

Board # 2004

Cerclage Para-Hisian Septal Pacing Through the Septal Perforator Branch of the Great Cardiac Vein: Bedside-To-Bench Development of a Novel Technique and Lead

**Nam Gi-Byoung** , Min Soo Cho, Asan Medical Ctr, Seoul, Korea, Republic of; Min Ku Chon, Pusan Natl Univ Yangsan Hosp, Yangsan, Korea, Republic of; Jin Hee Choi, PNUYH, Yangsan-si Gyeongsangnam, Korea, Republic of; Ki Won Hwang, Busan Natl Univ Yangsan Hosp, Yangsan, Korea, Republic of; Robert Lederman, NHLBI, Bethesda, MD; June-hong Kim, Pusan Natl Univ Yangsan Hosp, Yangsan, Korea, Republic of

12:30 PM

Board # 2005

High and Low Pacing Burden Associations for Pacemakers Implanted Post Tavr

Ethan Fry, Baylor Scott and White, Temple, TX; Jerry Fan, Baylor Scott and White - Temple, Temple, TX; **Arthur Davis** , Clinton Thurber, Baylor Scott and White, Temple, TX; Roxanne Bautista, Bryce Rhodehouse, Jordan Potter, Lily Shirazi, Baylor Scott and White, Temple, TX; Javier E Banchs, Baylor Scott & White Health - Texas A & M, Temple, TX

12:30 PM

Board # 2006

Pacemaker Therapy for the Treatment of Recurrent Neurocardiogenic Syncope: A Systematic Review and Meta-Analysis

**Marcelo Fernandes** , Emory Univ, Atlanta, GA; Neal Olarte, Univ of Miami-Jackson Memorial Hosp, Miami, FL; Gilson Fernandes, Alexander Toirac, Jennifer Maning, Raul Montanez-Valverde, Univ of Miami, Miami, FL; Kunal Bhatt, Faisal Merchant, Emory Univ, Atlanta, GA; Abhinav Goyal, Emory Sch of Med, Atlanta, GA

12:30 PM

Board # 2008

Transmission Rate of Remote Monitoring and Mortality in Patients With a Pacemaker

**Kento Mori** , Nagoya City Univ, Nagoya, Japan; Toshihiko Goto, Nagoya City Univ Graduate Sch, Nagoya, Japan; Kousuke Nakasuka, Marina Kato, Nagoya City Univ, Nagoya, Japan; Takafumi Nakayama, Dept of Cardio-Renal Med, Nagoya, Japan; Hiroshi Fujita, Nagoya City Univ, Nagoya, Japan; Kazuaki Wakami, Nagoya City Univ Graduate Sch, Nagoya, Japan; Hidekatsu Fukuta, Nagoya City Univ Grad Sch Med, Nagoya, Japan; Yoshihiro Seo, Nagoya City Univ, Nagoya, Japan; Nobuyuki Ohte, Nagoya City Univ Med Sch, Nagoya, Japan

12:30 PM

Board # 2009

Adapting a Neural Electrode Array for Selective His Bundle Sensing and Pacing

**Ankur Shah** , Univ of Utah, Salt Lake CIty, UT; Muhammad Shuja Khan, The Univ of Utah, Salt Lake City, UT; Derek J Dosdall, Univ of Utah, Salt Lake City, UT

# Best of AHA Specialty Conferences

## BASC.01 - Best of AHA Specialty Conferences: ATVB/PVD 2019

#### Best of Specialty Conferences, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 100

Activation of Oxidized Soluble Guanylate Cyclase Slows Progression of Aortic Valve Calcification

**Bin Zhang** , Carolyn Roos, Michael Hagler, Grace Verzosa, Heyu Zhang, Hartzell Schaff, Maurice Sarano, Jordan Miller, Mayo Clinic, Rochester, MN

12:30 PM

Board # 101

Single-cell Profiling of Atherosclerotic Tissue Identifies T Cell Subsets Associated with Cerebrovascular Events

**Dawn Fernandez** , Adeeb Rahman, Nicolas Fernandez, Aleksey Chudnovskiy, El-ad David Amir, Letizia Amadori, Nayaab Kahn, Roza Shamailova, Christopher Faries, Seunghee Kim-Schulze, J Mocco, Peter Faries, Miriam Merad, Chiara Giannarelli, Mount Sinai Sch of Med, New York, NY

12:30 PM

Board # 102

Neuropilin1 and PlGF/VEGF-B: a Novel Neuroimmune Pathway Involved in Angiotensin II-Induced Hypertension and Target Organ Damage

**Daniela Carnevale** , Sapienza Univ and IRCCS Neuromed, Pozzilli, Italy; Daniele Iodice, IRCCS Neuromed, Pozzilli, Italy; Sara Perrotta, Sapienza Univ, Pozzilli, Italy; Fabio Pallante, Roberta Iacobucci, Giuseppe Cifelli, IRCCS Neuromed, Pozzilli, Italy; Giuseppe Lembo, Sapienza Univ and IRCCS Neuromed, Pozzilli, Italy

12:30 PM

Board # 103

Acute Liver-Specific Deletion of HMG-CoA Reductase Results in Depletion of Essential Isoprenoids and ER Stress

**Marco De Giorgi** , Kelsey E Jarrett, Jason C Burton, Alexandria M Doerfler, Ayrea Hurley, Baylor Coll of Med, Houston, TX; Ang Li, Rice Univ, Houston, TX; Rachel H Hsu, Mia Furgurson, Baylor Coll of Med, Houston, TX; Jun Han, Christoph H Borchers, Univ of Victoria, Victoria, BC, Canada; William R Lagor, Baylor Coll of Med, Houston, TX

12:30 PM

Board # 104

Apolipoprotein(a) Secretion is Modulated by Sortilin, Proprotein Convertase Subtilisin/Kexin Type 9, and Microsomal Triglyceride Transfer Protein

Justin Clark, **Michael B Boffa** , Univ of Western Ontario, London, ON, Canada; Marlys L Koschinsky, Robarts Res Inst, London, ON, Canada

12:30 PM

Board # 105

**Vascular Smooth Muscle Cell PGC1alpha Deletion is Atheroprotective** in vivo

**Raymundo A Quintana Quezada** , Hassan Sellak, Derick Okwan-Duodu, Giji Joseph, Holly C Williams, Felipe Paredes, Alejandra San Martin, Bernard Lassegue, Div of Cardiology, Dept of Med, Emory Univ Sch of Med, Atlanta, GA; W Robert Taylor, Div of Cardiology, Dept of Med, Emory Univ Sch of Med; Atlanta Veterans Affairs Medical Ctr and Dept of Biomedical Engineering, Georgia Inst of Technology, Atlanta, GA

12:30 PM

Board # 106

The Non-Conserved Long Noncoding RNA, RP11-184M15.1, Regulates Macrophage Phenotype and Associates with Human Coronary Atherosclerosis

**Esther Cynn** , Ying Wang, Hanrui Zhang, Chenyi Xue, Jianting Shi, Daniel Y. Li, Muredach Reilly, Columbia Univ Medical Ctr, New York, NY

12:30 PM

Board # 107

Microvascular Pathology Influences Walking Performance in Patients with Peripheral Artery Disease

**Constance J Mietus** , Univ of Nebraska Medical Ctr, Omaha, NE; Matthew A Fuglestad, Timothy J Lackner, Gregory T Willcockson, Peter Karvelis, Hernan Hernandez, Yue Gao, Katyarina Brunette, Holly Despiegelaere, Feng Xie, Thomas Porter, Iraklis Pipinos, George Casale, UNMC, Omaha, NE

12:30 PM

Board # 108

**Heterozygous Missense Mutations in** PLEKHO2 **Predispose to Thoracic Aortic Aneurysms and Dissections**

**Amélie Pinard** , Xue-Yan Duan, Dongchuan Guo, Ellen S Regalado, Alana C Cecchi, Limin Gong, Tracy A Bensend, Ellen M Hostetler, The Univ of Texas Health Science Ctr at Houston, Houston, TX; University of Washington Center for Mendelian Genomics; Michael J Bamshad, Div of Genetic Med, Dept of Pediatrics, Univ of Washington, Seattle, WA; Deborah A Nickerson, Dept of Genome Sciences Univ of Washington, Seattle, WA; Dianna M Milewicz, The Univ of Texas Health Science Ctr at Houston, Houston, TX

12:30 PM

Board # 109

Chronic Obstructive Pulmonary Disease Promotes Aortic Aneurysm by Modulating Mitochondrial Fission in Transmural Macrophages

Tarik Hadi, George Miller, Lior Zangi, **Bhama Ramkhelawon** , NYU Medical Ctr, New York, NY

12:30 PM

Board # 110

Coronary Atheroma Regression from Serial Infusions of Autologous Selectively Delipidated Preβ-HDL-enriched Plasma on Coronary Atheroma in Patients With Homozygous Familial Hypercholesterolemia in the HALO-FH Trial

**Brian Ghoshhajra** , Borek Foldyna, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Daniel Gaudet, Etienne Khoury, Univ de Montréal and ECOGENE-21 Clinical and Translational Res Ctr, Chicoutimi, QC, Canada; Steven R Sloan, Boston Children's Hosp, Harvard Medical Sch, Boston, MA; Prediman K Shah, Cedars–Sinai Smidt Heart Inst, Los Angeles, CA; Steven R Jones, Johns Hopkins Univ, Baltimore, MD; Ron Waksman, Rebecca Torguson, Medstar Washington Hosp Ctr, Washington, DC; Ernst Schaefer, Tufts Univ, Boston, MA; H. Bryan Brewer, HDL Therapeutics, Inc., Vero Beach, FL

12:30 PM

Board # 111

Statin Use is Independently Associated with Premature Mortality, Cardiovascular-specific Mortality and Cardiovascular Events in Renal Transplant Recipients

Josephine L Anderson, Stephan J Bakker, Univ Medical Ctr Groningen, Groningen, Netherlands; **Uwe J Tietge** , Karolinska Instt, Stockholm, Sweden

12:30 PM

Board # 112

A Single Cell Survey of Smooth Muscle Cell Fate in Atherosclerosis

**Huize Pan** , Chenyi Xue, Jian Cui, Erin C. Bush, Hanrui Zhang, Robert C. Bauer, Wen Liu, Peter A. Sims, Muredach P. Reilly, Columbia Univ Medical Ctr, New York, NY

12:30 PM

Board # 113

Macspectrum Yields Unprecedented Resolution of Full Spectrum Macrophage Activation States in Atherosclerosis

**Chuan Li** , Antoine Menoret, Uconn Health, Farmington, CT; Cullen Farragher, Univ of Connecticut, Storrs, CT; Zhengqing Ouyang, The Jackson Lab for Genomic Med, Farmington, CT; Anthony T. Vella, Beiyan Zhou, Uconn Health, Farmington, CT

12:30 PM

Board # 114

Microbial Colonization Restores Neointimal Hyperplasia Development After Arterial Injury in Germ-Free Mice

**Edmund B Chen** , Northwestern Univ Feinberg Sch of Med, Chicago, IL; Katherine E Shapiro, Northwestern Univ, Feinberg Sch of Med, Chicago, IL; Thomas Kuntz, Betty Theriault, Univ of Chicago, Chicago, IL; Michael J. Nooromid, Kelly H Wun, Northwestern Univ, Feinberg Sch of Med, Chicago, IL; Vanessa Leone, Katharine Harris, Univ of Chicago, Chicago, IL; Qun Jiang, Northwestern Univ, Feinberg Sch of Med, Chicago, IL; Melanie Spedale, Univ of Chicago, Chicago, IL; Liqun Xiong, Owen M Eskandari, Northwestern Univ, Feinberg Sch of Med, Chicago, IL; Eugene B. Chang, Univ of Chicago, Chicago, IL; Karen J. Ho, Northwestern Univ, Feinberg Sch of Med, Chicago, IL

12:30 PM

Board # 115

Trib1 Hepatic Deficiency Impairs Low Density Lipoprotein Cholesterol Clearance, and Raises Plasma Lipids Through Both Low Density Lipoprotein Receptor Dependent and Independent Mechanisms

**Katherine Quiroz-Figueroa** , Andrea M Berrido, Mikhaila Smith, Cecilia Vitali, John S Millar, Univ of Pennsylvania, Philadelphia, PA; Robert C Bauer, Columbia Univ, New York, NY; Daniel J Rader, Univ of Pennsylvania, Philadelphia, PA

12:30 PM

Board # 116

DNA Base Editing in Hutchinson-Gilford Progeria Syndrome

Luke W. Koblan, Merkin Inst; Broad Inst of Harvard Univ and MIT; Howard Hughes Medical Inst, Cambridge, MA; Sean P. Doherty, Vanderbilt Univ Medical Ctr, Nashville, TN; Jon M. Levy, Merkin Inst; Broad Inst of Harvard Univ and MIT; Howard Hughes Medical Inst, Cambridge, MA; Michael R. Erdos, Francis S. Collins, NHGRI; NIH, Bethesda, MD; Charles Y. Lin, Baylor Coll of Med, Houston, TX; David R. Liu, Merkin Inst; Broad Inst of Harvard Univ and MIT; Howard Hughes Medical Inst, Cambridge, MA; **Jonathan D. Brown** , Vanderbilt Univ Medical Ctr, Nashville, TN

12:30 PM

Board # 117

Smooth Muscle Cell-derived Vascular Progenitor Cells Promote Arterial Remodeling and Fibrosis Through Loss of Hedgehog/Wnt/Β-catenin/Klf4 Activity

**Sizhao Lu** , Austin J Jolly, Keith A Strand, Karen S Moulton, Marie F Mutryn, Rebecca M Tucker, Raphael A Nemenoff, Mary C Weiser-Evans, Univ of Colorado Anschutz Medical Campus, Aurora, CO

12:30 PM

Board # 118

Cd4+ T Cell Deficiency of KLF10 Impairs Blood Flow and Neovascularization in Response to Tissue Hypoxia

**Akm Wara** , Brigham and Women's Hosp, Harvard Medical Sch, Boston, MA

12:30 PM

Board # 119

A Dual apoC-II mimetic-apoC-III Antagonist Peptide for Lowering Plasma Triglycerides

**Anna Wolska** , Natl Insts of Health, Bethesda, MD; Larry Lo, Corvidia Therapeutics, Inc., Waltham, MA; Denis O. Sviridov, Mohsen Pourmousa, Milton Pryor, Natl Insts of Health, Bethesda, MD; Soumitra S. Ghosh, Rahul Kakkar, Michael Davidson, Corvidia Therapeutics, Inc., Waltham, MA; Sierra Wilson, Richard W. Pastor, Jingrong Tang, Marcelo Amar, Natl Insts of Health, Bethesda, MD; Matt Devalaraja, Corvidia Therapeutics, Inc., Waltham, MA; Alan T. Remaley, Natl Insts of Health, Bethesda, MD

12:30 PM

Board # 120

Host Genotype-shaped Gut Microbiome Modulate Atherosclerosis Development in Mice

**Kazuyuki Kasahara** , Qijun Zhang, Eugenio I Vivas, Univ Wisconsin Madison, Madison, WI; Aldons J Lusis, Univ California Los Angeles, Los Angeles, CA; Federico E Rey, Univ Wisconsin Madison, Madison, WI

12:30 PM

Board # 121

Transgelin: A New Gene Involved in LDL Endocytosis in Liver Cells Identified by a Whole-genome Crispr-cas9 Screen

**Diego Lucero** , NHLBI-NIH, Bethesda, MD; Michael Mendelson, Boston Children's Hosp, Dept of Cardiology., Boston, MA; Promotto Islam, Lita A Freeman, Edward B Neufeld, Jingrong Tang, Christian Combs, Yuesheng Li, Alan T Remaley, NHLBI-NIH, Bethesda, MD

12:30 PM

Board # 122

Nck1 but not Nck2 Regulates Atherogenic Endothelial Activation via its first SH3 Domain's Specific Interactions

**Mabruka Alfaidi** , Jessica Lindquist, Anthony W Orr, LSU Health Sciences Ctr-Shrevepo, Shreveport, LA

# Best of AHA Specialty Conferences

## BASC.03 - Best of AHA Specialty Conferences: Hypertension 2019

#### Best of Specialty Conferences, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 161

Megalin: A Novel Endocytic Receptor for Prorenin and Renin?

Yuan Sun, Ingrid M. Garrelds, Erasmus Medical Ctr, Rotterdam, Netherlands; Xifeng Lu, Shenzhen Univ, Shenzhen, China; **A.H. Jan Danser** , Erasmus Medical Ctr, Rotterdam, Netherlands

12:30 PM

Board # 162

Racial Differences in Length of Stay and Hospital Expenses in Hypertension and Pregnancy

**Michael Z Grzeskowiak** , Navid Berenji, Son Pham, Rene Oliveros, Univ of Texas Health Science Ctr at San Antonio, San Antonio, TX

12:30 PM

Board # 163

Copeptin and Mid-Regional Pro-ANP in Women With Suspected or Confirmed Preeclampsia: Comparison With the sFlt-1/PlGF Ratio

Rugina Neuman, Maaike Alblas van der Meer, Langeza Saleh, Sjoerd van den Berg, Ton van den Meiracker, Willy Visser, **Jan Danser** , Erasmus Medical Ctr, Rotterdam, Netherlands

12:30 PM

Board # 164

Intensity of Hypertensive Exposure in Young Adulthood and Subclinical Atherosclerosis in Middle Age

**Zhenyu Xiong** , Sun Yat-Sen Univ, guangzhou, China; Jiaying Li, Nanfang Hosp of Southern Medical Univ, Guangzhou, China; Xiaodong Zhuang, Xinxue Liao, Sun Yat-Sen Univ, Guangzhou, China

12:30 PM

Board # 165

Antihypertensive Treatment Stops Cognition Decline in Elderly Chinese With Hypertension

**Shumin Rui** , IQVIA Biotech, FORT LEE, NJ; Chihua Li, L H Lumey, Columbia Univ, New York, NY

12:30 PM

Board # 166

Role of GRK4, a Risk Factor for Hypertension, in Breast Cancer

**Wei Yue** , Jiping Wang, Katherine Schiermeyer, Peng Xu, John Gil, Robin Felder, Univ of Virginia, Charlottesville, VA

12:30 PM

Board # 167

Sex-Differences in Fetal Programming of Cardiomyopathy Induced by Hypertensive Disorders of Pregnancy in Mice

Nissim Benizri, McGill Univ, Montréal, QC, Canada; Nozha Raguema, Casandra Marc, CIUSSS Nord-de-l'Île-de-Montréal, Montréal, QC, Canada; Émilie Pépin, Julie Lavoie, Univ de Montréal, Montréal, QC, Canada; **Mariane Bertagnolli** , CIUSSS Nord-de-l'Île-de-Montréal, Montréal, QC, Canada

12:30 PM

Board # 168

Role of Nox5 in Systemic Vascular Dysfunction in Ischemic Heart Disease

**Augusto C Montezano** , Raquel D Sarafian, Karla B Neves, Francisco J Rios, Patricia Passaglia, Livia L Camargo, Laura Haddow, Thomas J Ford, Michael Dunne, Rheure Alves-Lopes, Niall MacQuaide, Colin Berry, Godfrey Smith, Rhian M Touyz, ICAMS - Univ of Glasgow, Glasgow, United Kingdom

12:30 PM

Board # 169

Endothelin-1 Contributes to Vascular Dysfunction in Peri-Menopausal Women

**Megan M Wenner** , Univ of Delaware, Newark, DE; Kerrie L Moreau, Univ of Colorado Anschutz Medical Campus, Denver, CO

12:30 PM

Board # 170

Transplantation of Bone Marrow Cells from miR-150-KO Mice Improves Immune Function and Attenuates Arterial Stiffness and Hypertension in Senescence-Accelerated Mice

Jun Fan, Shirley Wang, **Zhongjie Sun** , Univ of Tennessee HSC, Memphis, TN

12:30 PM

Board # 171

Prevalence and Coincidence of Arterial Hypertension and Orthostatic Hypotension in Pre and Centenarians: Preliminary Results of Moscow Centenarian Study

**Kseniia Eruslanova** , Nadejda Runichina, Julia Kotovskay, Olga Tkacheva, Rg NKC, Moscow, Russian Federation

12:30 PM

Board # 172

Mode of Orthostatic Hypotension Assessment and Dizziness in Older Adults

**Stephen P Juraschek** , BIDMC-Harvard Medical Sch, Boston, MA; Edgar R Miller III, Erin D Michos, Lawrence J Appel, Johns Hopkins Univ, Baltimore, MD

12:30 PM

Board # 173

Proximal Tubule-Specific Deletion of the NHE3 (na+/h+ Exchanger 3) in the Kidney Attenuates Angiotensin II-Induced Hypertension in Mice

**Xiao C Li** , Dongmin Zhu, Xu Chen, Xiaowen Zheng, Chunling Zhao, Xinzhou Zhou, Univ Mississippi Medical Ctr, Jackson, MS; Manoocher Soleimani, UNIV Cincinnati Coll of Med, Cincinnati, OH; Isabelle Rubera, Michel Tauc, Univ Côte d'Azur, Nice, France; Jia L Zhuo, Univ Mississippi Medical Ctr, Jackson, MS

12:30 PM

Board # 174

Association of Central Arterial Stiffness With Hippocampal Blood Flow, N-Acetyl Aspartate and Anxiety in Hypertensive Dahl Salt Sensitive Rats

**Samuel Ajamu** , Rachel Fenner, Yulia Grigorova, Mustapha Bouhrara, Edward Lakatta, Richard Spencer, Kenneth Fishbein, Olga Fedorova, Natl Inst on Aging, Baltimore, MD

12:30 PM

Board # 175

Comparative Genomic Analysis and Functional Insights for Blood Pressure-Associated Single Nucleotide Polymorphisms

**Yong Liu** , Manoj Mishra, Eugene Liang, Aron Geurts, Medical Coll of Wisconsin, Milwaukee, WI; Paul W. Auer, Univ of Wisconsin-Milwaukee, Milwaukee, WI; Pengyuan Liu, Medical Coll of Wisconsin, Milwaukee, WI; Sridhar Rao, Blood Res Inst, Milwaukee, WI; Andrew Greene, Mingyu Liang, Medical Coll of Wisconsin, Milwaukee, WI

12:30 PM

Board # 176

Hypoxic Peripheral Chemoreceptor Activation Engages Sympathetic Brainstem and Hypothalamic Nuclei in Human Subjects

**Darius Andreas Gerlach** , German Aerospace Ctr, Cologne, Germany; Jorge Manuel, Hannover Medical Sch, Hannover, Germany; Alex Hoff, Hendrik Kronsbein, Fabian Hoffmann, Karsten Heusser, German Aerospace Ctr, Cologne, Germany; André Diedrich, Vanderbilt Univ, Nashville, TN; Heimo Ehmke, Univ Medical Ctr Eppendorf, Hamburg, Germany; Jens Jordan, Jens Tank, German Aerospace Ctr, Cologne, Germany; Florian Beissner, Hannover Medical Sch, Hannover, Germany

12:30 PM

Board # 177

Early and Late Post-Kidney Transplant Hypertension and Late Renal Allograft Outcome

**Ekamol Tantisattamo** , Div of Nephrology, Hypertension and Kidney Transplantation, Dept of Med, Univ of California Irvine Sch of Med, Orange, CA; Possawat Vutthikraivit, Phramongkutklao Coll of Med, Mahidol Univ, Bangkok, Thailand; Natnicha Leelaviwat, Faculty of Med, Ramathibodi Hosp, Mahidol Univ, Bangkok, Thailand; Siroj Dejhansathit, Phramongkutklao Coll of Med, Mahidol Univ, Babgkok, Thailand

12:30 PM

Board # 178

Differential Regulation of Renal Injury in _Npr1_ Gene-Targeted Male and Female Mice: Role of Class I-Specific HDAC Inhibitor

**Prerna Kumar** , Dept of Physiology,, New Orleans, LA; Kailash N. Pandey, Dept of Physiology, Tulane Univ Health Sciences Ctr and Sch of Med, New Orleans, LA

12:30 PM

Board # 179

The Effects of a Lower Blood Pressure Treatment Goal on Orthostatic Hypotension in Adults With Recent Stroke

Stephen P Juraschek, **Jennifer L Beach** , Anthony Ishak, Kenneth J Mukamal, BIDMC-Harvard Medical Sch, Boston, MA

12:30 PM

Board # 180

Interplay Between Nox5 and Endoplasmic Reticulum Stress Regulates Vascular Signalling in Human Hypertension

**Livia L Camargo** , Augusto C Montezano, Yu Wang, Univ of Glasgow, Glasgow, United Kingdom; Misbah Hussain, Fazli R Awan, Natl Inst for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan; Francisco J Rios, Rhian M Touyz, Univ of Glasgow, Glasgow, United Kingdom

12:30 PM

Board # 181

Blood Pressure Variation and Renal Functional Changes in Chronic Renal Insufficiency Patients With or Without Diabetes in a Large Cohort Study

**Ling Wang** , Kevin Pezeshkian, Donna Wang, Michigan State Univ, East Lansing, MI

12:30 PM

Board # 182

Genetic Deletion of Sirtuin 3 (SIRT3) in the Mitochondria of the Proximal Tubules Aggravates Angiotensin II-Induced Hypertension by Impairing the Pressure-Natriuresis Response in Proximal Tubule-Specific SIRT3 Knockout Mice

**Xiao C Li** , Xu Chen, Xiaowen Zheng, Chunling Zhao, Jian Xiong Chen, Jia L Zhuo, Univ Mississippi Medical Ctr, Jackson, MS

12:30 PM

Board # 183

Sex Differences in the Development of Age-Dependent Hypertension and the Salt Sensitivity of Blood Pressure

**Franco J Puleo** , Alissa A Frame, Parul Chaudhary, Richard D Wainford, Boston Univ Sch Med, Boston, MA

12:30 PM

Board # 184

Vitamin D Supplementation Improves Vascular Function in Adolescents Suffering from Orthostatic Intolerance

**Hossam A Shaltout** , Wake Forest Univ, Winston Salem, NC

12:30 PM

Board # 185

PLGF VEGFB Neuropilin1 a Neuroimmune Mechanism Necessary for the Initiation of the Adaptive Immune Response Recruited by Angiotensin II to Induce Hypertension and Target Organ Damage

**Daniela Carnevale** , Sapienza Univ and IRCCS Neuromed, Pozzilli, Italy; Daniele Iodice, IRCCS Neuromed, Pozzilli, Italy; Sara Perrotta, Sapienza Univ, Pozzilli, Italy; Lorenzo Carnevale, Roberta Iacobucci, IRCCS Neuromed, Pozzilli, Italy; Marialuisa Perrotta, Sapienza Univ, Pozzilli, Italy; Fabio Pallante, Giuseppe Cifelli, IRCCS Neuromed, Pozzilli, Italy; Giuseppe Lembo, Sapienza Univ and IRCCS Neuromed, Pozzilli, Italy

12:30 PM

Board # 186

Amplification of Systolic Blood Pressure and Pulse Pressure is Higher in Resistant Hypertensive Patients Irrespective of Blood Pressure Control

**Badhma Valaiyapathi** , Tanja Dudenbostel, Mohammed Siddiqui, Bin Zhang, Maria El Hachem, Suzanne Oparil, David A Calhoun, Univ of Alabama at Birmingham, Birmingham, AL

12:30 PM

Board # 187

Proximal Tubule-Specific Knockout of Angiotensin II Type 1a Receptors in the Kidney Augments the Natriuretic Response to Angiotensin III in Mice

Chunling Zhao, Xiao Chun Li, Xu Chen, Xiaowen Zheng, **Jia Long Zhuo** , Univ Mississippi Medical Ctr, Jackson, MS

12:30 PM

Board # 188

Genetic Polymorphisms Associated With Apparent Treatment-Resistant Hypertension in Patients With Chronic Kidney Disease

**Ling Wang** , Kevin Pezeshkian, Donna Wang, Michigan State Univ, East Lasing, MI

# Best of AHA Specialty Conferences

## BASC.05 - Best of AHA Specialty Conferences: ISC 2019

#### Best of Specialty Conferences, Science and Technology Hall

### Sunday, November 17, 2019, 12:30 PM - 1:00 PM

12:30 PM

Board # 221

Influenza-like Illness and Risk of Stroke in New York State

Trevor Alvord, Erin Kulick, Michelle Cannine, Mitchell Elkind, **Amelia K Boehme** , Columbia Univ, New York, NY

12:30 PM

Board # 222

Association Between Uric Acid and Stroke in the REgards Case-cohort Study

**Ninad S Chaudhary** , Univ of Alabama at Birmingham, Birmingham, AL; Angelo L Gaffo, Univ of Alabama Sch of Med, Birmingham, AL; Mary Cushman, The Univ of Vermont Medical Ctr, Burlington, VT; Lisandro D Colantonio, Emily B Levitan, Suzanne E Judd, Univ of Alabama at Birmingham, Birmingham, AL; Jasvinder Singh, Nita A Limdi, S Louis Bridges Jr, Univ of Alabama Sch of Med, Birmingham, AL; George Howard, Univ of Alabama at Birmingham, Birmingham, AL; Richard J Reynolds IV, Univ of Alabama Sch of Med, Birmingham, AL; Marguerite R Irvin, Univ of Alabama at Birmingham, Birmingham, AL

12:30 PM

Board # 224

Viscerotoxic Brain Infarcts: The Results of Heart-Brain Interactions Study

Ken Chang, James Brown, Andrew Beers, Jayashree Kalpathy-Cramer, **Hakan Ay** , Mass General Hosp, Boston, MA

12:30 PM

Board # 225

Thrombectomy is Safe for Dawn- and Defuse-3-Ineligible Patients Who Present Within the Extended Window: A Subgroup Analysis From the BEST Prospective Cohort Study

**James E Siegler** , Steven R. Messé, Hosp of the Univ of Pennsylvania, Philadelphia, PA; Heidi Sucharew, Hosp of the Univ of Pennsylvania, Cincinnati, OH; Tapan Mehta, Univ of Minnesota Medical Ctr, Minneapolis, MN; Niraj Arora, Jackson Memorial Hosp, Miami, FL; Amy K. Starosciak, Felipe De Los Rios La Rosa, Baptist Health Neuroscience Ctr, Miami, FL; Natasha R. Barnhill, Oregon Health and Science Univ, Portland, OR; Akshitkumar M. Mistry, Vanderbilt Univ Medical Ctr, Nashville, TN; Kishan Patel, Houston Methodist Neurological Hosp, Houston, TX; Salman Assad, Amjad Tarboosh, Henry Ford Health System, Detroit, MI; Katarina Dakay, Brown Univ, Providence, RI; Jeff Wagner, Alicia Bennett, Blue Sky Neurology, Englewood, CO; Bharathi Jagadeesan, Christopher Streib, Univ of Minnesota Medical Ctr, Minneapolis, MN; Stewart A. Weber, Oregon Health and Science Univ, Portland, OR; Rohan Chitale, Vanderbilt Univ Medical Ctr, Nashville, TN; John J. Volpi, Houston Methodist Neurological Hosp, Houston, TX; Stephan A. Mayer, Henry Ford Health System, Detroit, MI; Shadi Yaghi, Mahesh Jayaraman, Brown Univ, Providence, RI; Pooja Khatri, Univ of Cincinnati, Cincinnati, OH; Eva Mistry, Vanderbilt Univ Medical Ctr, Nashville, TN

12:30 PM

Board # 226

Leisure-time Physical Activity Reduces the Risk for Stroke in Adults: A Meta-Analysis of Prospective Cohort Studies

**George A Kelley** , Kristi S Kelley, West Virginia Univ, Morgantown, WV

12:30 PM

Board # 227

Establishing Sensitivity and Specificity of the Maxwell Swallow Screen

**Elizabeth A Peters** , Rebekah Maxwell, Lucy Leclerc, WellStar Cobb Hosp, Austell, GA; Nancy Ballard, Lewis VanBrackle, Kennesaw State Univ, Kennesaw, GA

12:30 PM

Board # 228

Mesenchymal Stem Cell Derived Exosomes as a Modulator of Neuroinflammation Following Cortical Injury

**Veronica Go** , Boston Univ Sch of Med, Boston, MA; Bethany Bowley, Douglas Rosene, Maria Medalla, Boston Univ, Boston, MA; Benjamin Buller, Henry Ford Health System, Detroit, MI; Tara Moore, Boston Univ, Boston, MA

12:30 PM

Board # 229

Long-Term Impact of Mechanical Thrombectomy Randomized Trials in a Comprehensive Stroke Center: Individual Ethical Dilemmas versus Societal Benefits

**Raul G Nogueira** , Gabriel M Rodrigues, Michael Frankel, Diogo C Haussen, Emory Univ, Atlanta, GA

12:30 PM

Board # 230

Endothelium-Specific Sox17 Deletion Ameliorates ALK1-mediated Arteriovenous Malformation (AVM)

**Moinay Kim** , Wonhyoung Park, Jae Sung Ahn, Seungjoo Lee, ASAN Medical Ctr, Seoul, Korea, Republic of

12:30 PM

Board # 231

Frequency of Blood Brain Barrier Disruption in Acute Stroke Patients Post Endovascular Therapy and Its Association With Multiple Thrombectomy Passes and Clinical Outcome

**Marie Luby** , NINDS, Stroke Branch, Bethesda, MD; Zurab Nadareishvili, Johns Hopkins Community Physicians, Bethesda, MD; Kaylie Cullison, Noorie Pednekar, NINDS, Stroke Branch, Bethesda, MD; Amie W Hsia, Medstar Washington Hosp Ctr, Washington, DC; Lawrence L Latour, NINDS, Stroke Branch, Bethesda, MD

12:30 PM

Board # 232

Ischemic Conditioning Improves Brachial Artery Flow Mediated Dilation in Chronic Stroke Survivors

**Matthew J Durand** , Jennifer Nguyen, Michael T. Wright, David D. Gutterman, Medical Coll of Wisconsin, Milwaukee, WI; Brian D. Schmit, Allison S. Hyngstrom, Marquette Univ, Milwaukee, WI

12:30 PM

Board # 233

Effect of Single Pass Recanalization in Acute Ischemic Stroke With Large Vessel Occlusion: Sub-Analysis of Rescue-Japan Registry 2

**Soichiro Numa** , Shinichi Yoshimura, Hyogo Coll of Med, Nishinomiya, Japan; Nobuyuki Sakai, Kobe City Medical Ctr General Hosp, Kobe, Japan; Hiroshi Yamagami, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Takeshi Morimoto, Hyogo Coll of Med, Nishinomiya, Japan; Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism Japan Registry 2 Investigators

12:30 PM

Board # 234

Direct Oral Anticoagulant Underdosing Increases Rates of Mortality, Stroke and Myocardial Infarction with No Reduction in Bleeding Rate

**Ronen Arbel** , Sapir Coll, Sderot, Israel; Ariel Hammerman, Clalit Health Services, Tel Aviv, Israel; Ruslan Sergeinko, Ben-Gurion Univ of the Negev, Beer Sheva, Israel; Erez Batat, Sari Greenberg-Dotan, Clalit Health Services, Tel Aviv, Israel; Orly Avnery, Martin H Ellis, Meir Medical Ctr, Kfar Saba, Israel

12:30 PM

Board # 235

Delayed Egress of CD8 T Cells Contributes to Long-Term Pathology After Ischemic Stroke in Mice

Uma Maheswari Selvaraj, Vanessa O Torres, Xiangmei Kong, Erik J. Plautz, UT Southwestern Medical Ctr, Dallas, TX; **Ann M Stowe** , Univ of Kentucky, Lexington, KY

12:30 PM

Board # 236

Physiologic Predictors of Collateral Circulation and Infarct Growth in Setting of Anesthesia During Thrombectomy: Detailed Analysis of the GOLIATH Trial

**Radoslav I Raychev** , David S Liebeskind, UCLA, Los Angeles, CA; Scott Brown, NAMSA, Minneapolis, MN; Dimiter Arnaudov, USC, Los Angeles, CA; Albert Yoo, Texas Stroke Inst, Dallas, TX; Saver Jeffrey, UCLA, Los Angeles, CA; Claus Z Simonsen, Aarhus Univ Hosp, Arhus, Denmark

12:30 PM

Board # 237

Low Socioeconomic Status and Longer Home-to-Hospital Distances Are Associated With Less Timely Treatment of Ischemic Stroke

**Jeremy Ader** , Columbia Univ Medical Ctr, New York, NY; Jingjing Wu, Duke Univ, Durham, NC; Gregg C. Fonarow, Ronald Reagan-UCLA Medical Ctr, Los Angeles, CA; Eric E. Smith, Univ of Calgary, Calgary, AB, Canada; Shreyansh Shah, Ying Xian, Duke Univ, Durham, NC; Deepak L. Bhatt, Lee H. Schwamm, Harvard Medical Sch, Boston, MA; Mathew J. Reeves, Michigan State Univ, East Lansing, MI; Roland A. Matsouaka, Duke Univ, Durham, NC; Kevin N. Sheth, Yale Univ, New Haven, CT

12:30 PM

Board # 238

Reduction in Perihematomal Edema Leads to Improved Clinical Outcomes: Results from the MISTIE III Trial

**W. Andrew Mould** , Johns Hopkins Univ, Baltimore, MD; John Muschelli, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Radhika Avadhani, Nichol McBee, Karen Lane, Johns Hopkins Univ, Baltimore, MD; Richard Thompson, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Wendy Ziai, Johns Hopkins Univ, Baltimore, MD; Mario Zuccarello, Univ of Cincinnati, Cincinnati, OH; Issam Awad, Univ of Chicago, Chicago, IL; Daniel F Hanley, Johns Hopkins Univ, Baltimore, MD

12:30 PM

Board # 239

Cortical tau Pathology in Cerebral Amyloid Angiopathy

**Edip M Gurol** , J. Alex Becker, Elif Gokcal, Panagiotis Fotiadis, Kristin M. Schwab, Joshua N. Goldstein, Jonathan Rosand, Anand Viswanathan, Keith A. Johnson, Steve M. Greenberg, Massachusetts General Hosp, Boston, MA

12:30 PM

Board # 240

DAWN versus Modified Clinical-ASPECTS Mismatch Selection for Stroke Endovascular Therapyin the Early and Late Time Windows

**Mehdi Bouslama** , Diogo Haussen, Jonathan Grossberg, Gabriel Rodrigues, Clara Barreira, Michael Frankel, Raul Nogueira, Emory Univ SOM/Grady Memorial Hosp, Atlanta, GA

12:30 PM

Board # 241

Tenecteplase is Non-Inferior to Alteplase for Acute Ischemic Stroke: Formal Meta-Analysis of 5 Completed Randomized Trials

**Adrian M Burgos** , Jeffrey L Saver, Geffen Sch of Med at UCLA, Los Angeles, CA

12:30 PM

Board # 242

Effects of the Endpoint Adjudication Process on the Results of the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial

**Mary Farrant** , John D. Easton, UC San Francisco, San Francisco, CA; Eric E. Adelman, Univ of Wisconsin, Madison, WI; William G. Barsan, Univ of Michigan, Ann Arbor, MI; Brett L. Cucchiara, Univ of Pennsylvania, Philadelphia, PA; Jordan L. Elm, Holly Tillman, Medical Univ of South Carolina, Charleston, SC; Anthony S. Kim, UC San Francisco, San Francisco, CA; Anne S. Lindblad, The Emmes Corp, Rockville, MD; Yuko Y. Palesch, Medical Univ of South Carolina, Charleston, SC; S. C. Johnston, Univ of Texas at Austin, Austin, TX; POINT Investigators

12:30 PM

Board # 243

Inpatient Nursing Stroke Champions Improve Stroke Education Retention at 7 Days and 90 Days Post Discharge

**Lorina Punsalang** , Christina McDaniels, Denise Gaffney, Ariane Sta Maria, Claudine Perez, Alvina Mkrtumyan, Zahra Ajani, Duy Le, Navdeep Sangha, Kaiser Permanente Los Angeles Medical Ctr, Los Angeles, CA

12:30 PM

Board # 244

Idarucizumab in Patients Treated With Dabigatran Suffering Cerebral Ischemia or Intracranial Hemorrhage: A Retrospective Case Series From Germany

**Pawel Kermer** , Nordwest-Krankenhaus Sanderbusch, Sande, Germany; Christoph C Eschenfelder, Boehringer Ingelheimn, Ingelheim, Germany; Hans-Christoph Diener, Univ Duisburg-Essen, Essen, Germany; Martin Grond, Kreisklinikum Siegen, Siegen, Germany

12:30 PM

Board # 245

North Dakota Mission: Lifeline Stroke Survey of Symptom Awareness Indicates Need for Public Education

**Mindy Cook** , American Heart Association, Eagan, MN; Shiraz Hyder, CHI St. Alexius Medical Ctr, Bismarck, ND; Jeffrey Sather, Trinity Health, Minot, ND; Chrissy Meyer, American Heart Association, Sioux Falls, SD; Janna Pietrzak, American Heart Association, Jamestown, ND

12:30 PM

Board # 246

Is Low Heart Rate Variability, a Marker of Autonomic Dysfunction, the Missing Link Between Migraine With Visual Aura and Cardioembolic Stroke?

**Tushar Trivedi** , Michelle Androulakis, Kolby T Redd, USC Sch of Med, Columbia, SC; Alvaro Alonso, Emory Univ, Atlanta, SC; Elsayed Soliman, Wake Forest Sch of Med, Winston Salem, NC; Jared Magnani, Univ of Pittsburgh Medical Ctr, Pitssburgh, PA; Rebecca Gottesman, Johns Hopkins Univ Sch of Med, Baltimore, SC; Wayne Rosamond, Univ of North Carolina - Chapel Hill, Chapel Hill, NC; Souvik Sen, USC Sch of Med, Columbia, SC

12:30 PM

Board # 247

Gender and Racial Disparities in Secondary Prevention of Stroke

**Paul M Ndunda** , Tabitha M Muutu, Univ of Kansas Sch of Med-Wichita, Wichita, KS

12:30 PM

Board # 248

NIH Stroke Scale Items Associated With Poor Outcomes in Patients 'Too Good To Treat' With IV Alteplase

**Syed F Ali** , Thomas Hemmen, Univ California, San Diego, La Jolla, CA; Natalia Rost, Christopher Anderson, Mark Etherton, Lee H. Schwamm, Massachusetts General Hosp, Boston, MA

12:30 PM

Board # 249

Predictors of Post-Stroke Depression in Ischemic Stroke Patients using the Patient Health Questionnaire-9

**Lauren E Fournier** , Xu Zhang, Esther Bonojo, Mary Love, Jennifer Sanner, Gabretta Cooksey, Evelyn Hinojosa, Munachi N Okpala, Sean I Savitz, Anjail Z Sharrief, The Univ of Texas Health Science Ctr at Houston, Houston, TX

12:30 PM

Board # 250

Higher Soluble CD14 Level is a Risk Factor for Ischemic Stroke in Black but Not White Participants of the Reasons for Geographical and Racial Differences in Stroke (REGARDS) Study

**Nels C. Olson** , Insu Koh, Univ of Vermont, Colchester, VT; Alex P. Reiner, Univ of Washington, Seattle, WA; Suzanne E. Judd, Marguerite R. Irvin, George Howard, Univ of Alabama at Birmingham, Birmingham, AL; Neil A. Zakai, Mary Cushman, Univ of Vermont, Colchester, VT

12:30 PM

Board # 251

CAS versus CEA Treatment Differences in Long-Term Outcomes and Post-Procedural Durability: the Carotid Stenosis Trialist Collaboration (CSTC)

**Thomas Gordon Brott** , Mayo Clinic Florida, Jacksonville, FL; David Calvet, Ctr Hospier Sainte Anne, Paris, France; George Howard, Univ of Alabama at Birmingham, Birmingham, AL; John Gregson, London Sch of Hygeine and Tropical Med, London, United Kingdom; Ale Algra, Univir Medisch Centrum Utrecht, Heidelberglaan, Netherlands; Jean-Pierre Becquemin, Vascular Inst of Paul D' Egine Hosp, Champigny-sur-Marne, France; Martin M Brown, Natl Hosp for Neurology and Neurosurgery, London, United Kingdom; Richard Bulbulia, Cheltenham General Hosp, Cheltenham, United Kingdom; Hans-Henning Eckstein, Technical Univ of Munich, Munich, Germany; Gustav Fraedrich, Medische Univ Innsbruck, Innsbrock, Austria; Alison Halliday, Univ of Oxford, Oxford, United Kingdom; Joroen Hendrikse, Univ Medical Ctr Utrecht, Utrecht, Netherlands; Olav Jansen, Christian-Albrechts-Univ zu Kiel, Kiel, Germany; Gary S Roubin, Brookwood Baptist Health, Birmingham, AL; Peter A Ringleb, Univ Hosp Heidelberg, Heidelberg, Germany; Jean-Louis Mas, Sainte-Anne Hosp, Paris, France; Leo H Bonati, Univ Hosp Basel, Basel, Switzerland

12:30 PM

Board # 252

Factors Affecting Readmission Rates for Patients With Ischemic Stroke Hospitalized in an Integrated Health System of Stroke Care

**Scott M Le** , Duke Health, Durham, NC; Julie Fussner, Cathy Sila, Univ Hosp, Cleveland, OH

12:30 PM

Board # 253

Intravenous Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke Patients With Recent Myocardial Infarction

**Taku Inohara** , Li Liang, Andrzej Kosinski, Duke Clinical Res Inst, Durham, NC; Eric E Smith, Hotchkiss Brian Inst, Calgary, AB, Canada; Lee H Schwamm, Massachusetts General Hosp, Boston, MA; Adrian F Hernandez, Duke Clinical Res Inst, Durham, NC; Deepak L Bhatt, Brigham and Women's Hosp Heart and Vascular Ctr, Boston, MA; Gregg C Fonarow, Ronald Reagan Univ of California, Los Angeles, CA; Eric D Peterson, Ying Xian, Duke Clinical Res Inst, Durham, NC

12:30 PM

Board # 254

Treatment Trends and Clinical Outcomes for Unruptured Cerebral Aneurysms in High vs Low Volume Centers

**Mehmet E Inam** , Aditya A Sanzgiri, Peng Roc R Chen, Spiros Blackburn, Arvind B Bambhroliya, Farhaan S Vahidy, Sean I Savitz, Sunil A Sheth, UTHealth McGovern Medical Sch, Houston, TX

12:30 PM

Board # 255

FAST-ED Based Pre-Hospital Stroke Triage System Improves Endovascular Treatment Times, Especially off Hours

**Helen E. Rynor** , Florida Intl Univ, Miami, FL; Amy K Starosciak, Jayme Strauss, Felipe De Los Rios La Rosa, Baptist Health South Florida, Miami, FL

12:30 PM

Board # 256

**Secondary Stroke Prevention With Aspirin and Clopidogrel in** CYP2C19 ***17 Carriers Increases Risk of Major Non-CNS Bleeding**

**Alexis Netis Simpkins** , Caitrin W McDonough, Univ of Florida, Gainesville, FL; Leslie A McClure, Drexel Univ, Philadelphia, PA; Braxton D Mitchell, Univ of Maryland; Veterans Admin Medical Ctr, Baltimore, MD; Alan R Shuldiner, Univ of Maryland, Baltimore, MD; Oscar R Benavente, Univ of British Columbia, Vancouver, BC, Canada; Julie A Johnson, Univ of Florida, Gainesville, FL

12:30 PM

Board # 257

**Large Aortic Arch Plaques are Associated With CHADS** 2 **and CHA** 2 **DS** 2 **-VASc Scores: A Multicenter Registry Analysis**

**Yuji Ueno** , Juntendo Univ Sch of Med, Tokyo, Japan; Yohei Tateishi, Nagasaki Univ Hosp, Nagasaki, Japan; Ryosuke Doijiri, Iwate Prefectural Central Hosp, Morioka, Japan; Ayako Kuriki, Showa Univ Koto Toyosu Hosp, Tokyo, Japan; Takahiro Shimizu, St. Marianna Univ Sch of Med, Kawasaki, Japan; Muneaki Kikuno, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Yoshiaki Shimada, Juntendo Univ Urayasu Hosp, Urayasu, Japan; Hidehiro Takekawa, Dokkyo Medical Univ, Tochigi, Japan; Eriko Yamaguchi, Iwate Prefectural Central Hosp, Morioka, Japan; Masatoshi Koga, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Yuki Kamiya, Showa Univ Koto Toyosu Hosp, Tokyo, Japan; Masafumi Ihara, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Akira Tsujino, Nagasaki Univ Hosp, Nagasaki, Japan; Koichi Hirata, Dokkyo Medical Univ, Tochigi, Japan; Kazunori Toyoda, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Yasuhiro Hasegawa, St. Marianna Univ Sch of Med, Kawasaki, Japan; Nobutaka Hattori, Juntendo Univ Sch of Med, Tokyo, Japan; Takao Urabe, Juntendo Univ Urayasu Hosp, Urayasu, Japan

# Meet the Trialists

## CS.MT.04 - Meet the Trialists DAPA-HF

#### EP Central

### Sunday, November 17, 2019, 12:30 PM - 1:15 PM

12:30 PM

DAPA-HF

Felipe Martinez, Cordoba, Argentina

# Presidential Session

## PS.01 - Presidential Session

#### Main Event I

### Sunday, November 17, 2019, 12:45 PM - 2:37 PM

12:45 PM

**Performance of Select Songs from the Stars of the Broadway Musical,** Hamilton

1:01 PM

Welcome and Introduction, Nancy Brown, CEO

1:03 PM

Conner Presidential Address

Robert A Harrington, Stanford, CA

1:28 PM

In Memoriam

1:30 PM

Presidential Session Awards

1:50 PM

Keynote Address by Murat Sönmez, World Economic Forum

2:10 PM

Remarks by AHA CEO Nancy Brown

2:20 PM

Final Remarks

Robert A Harrington, Stanford, CA

2:22 PM

**Performance of Select Songs from the Stars of the Broadway Musical,** Hamilton

# Expert Theater

## ET.16 - Amarin Pharma, Inc.

#### Game Central, Booth # 6

### Sunday, November 17, 2019, 1:15 PM - 2:00 PM

This is not a CME/CE certified session

# Expert Theater

## ET.17 - Amgen, Inc.

#### Heart Theater, Booth # 17

### Sunday, November 17, 2019, 1:15 PM - 2:00 PM

This is not a CME/CE certified session

# Expert Theater

## ET.18 - Bristol-Myers Squibb and Pfizer

#### Learning Studio 2, Booth # 7

### Sunday, November 17, 2019, 1:15 PM - 2:00 PM

This is not a CME/CE certified session

# Expert Theater

## ET.19 - Novartis Pharmaceuticals Corp.

#### Learning Studio 1, Booth # 5

### Sunday, November 17, 2019, 1:15 PM - 2:00 PM

This is not a CME/CE certified session

# Abstract Oral Session

## SA.AOS.534 - Cardiothoracic Surgery Translational Experimental Trials and Therapies

#### 103C

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

J Michael Dimaio, Dallas, TX

2:00 PM

Preclinical Efficacy Studies of Human Ips Cell-derived Cardiac Tissue Transplantation Onto Animal Heart Disease Models

**Hidetoshi Masumoto** , Riken Ctr for Biosystems Dynamics Res, Kobe, Japan; Shingo Hirao, Shinya Takimoto, Masahide Kawatou, Tadashi Ikeda, Graduate Sch of Med, Kyoto Univ, Kyoto, Japan; Yasuhiko Tabata, Inst for Frontier Life and Medical Sciences, Kyoto Univ, Kyoto, Japan; Jun Yamashita, Ctr for iPS Cell Res and Application, Kyoto Univ, Kyoto, Japan; Kenji Minatoya, Graduate Sch of Med, Kyoto Univ, Kyoto, Japan

2:10 PM

Q & A

2:15 PM

Progression of Tricuspid Regurgitation After Surgery for Ischemic Mitral Regurgitation: From the Cardiothoracic Surgical Trials Network

**Philippe Bertrand** , Xin Zeng, Massachusetts General Hosp, Boston, MA; Jessica R Overbey, Icahn Sch of Med at Mount Sinai, New York, NY; Gorav Ailawadi, Univ of Virginia, Charlottesville, VA; Michael Andrew Acker, Univ of Pennsylvania, Philadelphia, PA; Peter K Smith, Duke Univ Medical Ctr, Durham, NC; Vinod H Thourani, Medstar Washington Hosp Ctr, Washington, DC; Emilia Bagiella, Icahn Sch of Med at Mount Sinai, New York, NY; Marissa Miller, Natl Heart Lung and Blood Inst, Bethesda, MD; Lopa Gupta, Icahn Sch of Med at Mount Sinai, New York, NY; Michael Joseph Mack, Baylor Scott & White Health, Plano, TX; A. Marc Gillinov, Cleveland Clinic, Cleveland, OH; Gennaro Giustino, Mount Sinai Sch of Med, New York, NY; Alan J Moskowitz, Icahn Sch of Med at Mount Sinai, New York, NY; Annetine C Gelijns, Icahn Sch of Med-Mt Sinai, New York, NY; Michael Bowdish, Univ of Southern California, Los Angeles, CA; Patrick T O'Gara, Brigham and Women's Hosp, Boston, MA; James S Gammie, Univ Maryland Medical Ctr, Baltimore, MD; Judy Hung, Massachusetts General Hosp, Boston, MA

2:25 PM

Q & A

2:30 PM

Association of Ischemic Mitral Regurgitation Proportionality With Outcomes After Mitral Valve Surgery: A Cardiothoracic Surgical Trials Network Analysis

**Gennaro Giustino** , Jessica Overbey, Icahn Sch of Med at Mount Sinai, New York, NY; Patrick T O'Gara, Brigham and Women's Hosp, Boston, MA; Annetine C Gelijns, Icahn Sch of Med at Mount Sinai, New York, NY; Lynne Warner Stevenson, Vanderbilt Univ Medical Ctr, Nashville, TN; Alan J Moskowitz, Icahn Sch of Med at Mount Sinai, New York, NY; Pierre Voisine, IUCPQ, Quebec, QC, Canada; Michael Joseph Mack, Baylor Scott & White Health, Plano, TX; Michael Andrew Acker, Univ of Pennsylvania, Philadelphia, PA; A. Marc Gillinov, Cleveland Clinic, Cleveland, OH; Donna Marie Mancini, Mount Sinai Hosp, New York, NY; Emilia Bagiella, Icahn Sch of Med at Mount Sinai, New York, NY; Anuradha Lala, Mount Sinai Hosp, New York, NY; Y. Joseph Woo, Stanford Univ Sch Med, Stanford, CA; Judy Hung, Massachusetts General Hosp, Boston, MA; Paul A Grayburn, Baylor Scott and White Heart Hosp, Dallas, TX

2:40 PM

Q & A

2:45 PM

Should We Wait for the Gradient to Reach 40 mmHg in Paradoxical Low-flow Aortic Stenosis?

**Ezequiel Guzzetti** , IUCPQ, Quebec, QC, Canada; Mohamed-Salah Annabi, Québec Heart and Lung Inst, Québec-City, QC, Canada; Anthony Poulin, IUCPQ, Qu?bec, QC, Canada; Bin Zhang, IUCPQ, Quebec, QC, Canada; Dimitri Kalavrouziotis, Quebec Heart and Lung Inst, Quebec City, QC, Canada; Christian Couture, IUCPQ, Quebec, QC, Canada; francois dagenais, Laval Hosp, Quebec, QC, Canada; Philippe Pibarot, IUCPQ-UL, Quebec, QC, Canada; Marie Annick Clavel, IUCPQ, Quebec, QC, Canada

2:55 PM

Q & A

3:00 PM

Long-term Follow Up of Patients With Uncomplicated versus Complicated Acute Type B Aortic Dissection Managed With Early TEVAR

Ibrahim Sultan, **VAlentino Bianco** , Edgar Aranda-Michel, Arman Kilic, Adrian Zalewski, Forozan Navid, Univ of Pittsburgh, Pittsburgh, PA; Thomas G Gleason, UPMC Shadyside, Pittsburgh, PA

3:10 PM

Q & A

# Abstract Oral Session

## PH.AOS.479 - Dickinson W. Richards Memorial Lecture

#### 102AB

### Sunday, November 17, 2019, 2:00 PM - 3:00 PM

2:00 PM

Moderator

Fumito Ichinose, Boston, MA

2:00 PM

Moderator

Sarah M Perman, Aurora, CO

2:00 PM

Moderator

Paul B Yu, Boston, MA

2:25 PM

Q & A

2:30 PM

Identification of Emetine as a Therapeutic Agent for Pulmonary Arterial Hypertension-Novel Effects of an Old Drug

**Mohammad Abdul Hai Siddique** , Kimio Satoh, Ryo Kurosawa, Nobuhiro Kikuchi, Md. Elias- Al-Mamun, Tohoku Univ, Sendai, Japan; Junichi Omura, Laval Univ, Quebec City, QC, Canada; Taijyu Satoh, Masamichi Nogi, Shinichiro Sunamura, Satoshi Miyata, Hirofumi Ueda, Hidetoshi Tokuyama, Tohoku Univ, Sendai, Japan; Hiroaki Shimokawa, Tohoku Univ Grad Sch Med, Sendai City, Japan

2:40 PM

Q&A

2:45 PM

Sex Hormones Directly Regulate Microtubules: New Insights Into Sex-Differences in Right Ventricular Function in Pulmonary Arterial Hypertension

Ping Yu Xiong, Stephen L Archer, Queen's Univ, Kingston, ON, Canada; **Kurt W Prins** , Univ of Minnesota, Minneapolis, MN

2:55 PM

Q&A

# Abstract Oral Session

## NR.AOS.361 - High Tech Self-Care: Innovations in Practice

#### 118C

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Erica Schorr, Minneapolis, MN

2:00 PM

Moderator

Ruth M Masterson Creber, New York, NY

2:00 PM

Effectiveness of Mobile Health Technology Interventions on Patients With Heart Failure: Systematic Review and Meta-Analysis

**Spyros Kitsiou** , Haleh Vatani, Univ of Illinois at Chicago, Chicago, IL; Guy Paré, HEC Montreal, Montreal, QC, Canada; Ben Gerber, Univ of Illinois at Chicago, Chicago, IL; Susan Weber Buchholz, Rush Univ Coll of Nursing, Chicago, IL; Mayank Mohan Kansal, Univ of Illinois at Chicago, Chicago, IL; Ruth M Masterson Creber, Weill Cornell Med, New York, NY

2:10 PM

Q & A

2:15 PM

Results of the Diabetes LIVE Trial: An Immersive Virtual Environment for Diabetes Self-Management Training and Support

**Allison Vorderstrasse** , Gail D Melkus, New York Univ, New York, NY; Wei Pan, Mark Feinglos, Sathya Amarasekara, Katherine Pereira, Duke Univ, Durham, NC; Louise Reagan, Univ of Connecticut, Storrs, CT; Kathryn Kreider, Sarah Nowlin, Andrew Burd, Nancy Hassell, Duke Univ, Durham, NC; Constance Johnson, The Univ of Texas, Houston, TX

2:25 PM

Q & A

2:30 PM

Feasibility of Using Mobile Health Technology to Deliver Life's Simple 7 Messages for Atrial Fibrillation Management

**Meghan Reading Turchioe** , Weill Cornell Med, New York, NY; Suzanne Bakken, Columbia Univ, New York, NY; Ruth M Masterson Creber, Weill Cornell Med, New York, NY

2:40 PM

Q & A

2:45 PM

Understanding the Mechanism of App-Based Intervention Effects in Physically Inactive Women in the mPED Trial

**Yoshimi Fukuoka** , UCSF, San Francisco, CA; William L Haskell, Stanford Medical Sch, Palo Alto, CA; Feng Lin, Eric Vittinghoff, UCSF, San Francisco, CA

2:55 PM

Q & A

3:00 PM

Technologies for Innovative Monitoring to Reduce Blood Pressure Using Mobile Phones in Adult and Elderly Populations (Tim Study): A Randomized Controlled Trial

**Sandra C Fuchs** , Erno Harzheim, Cirano Iochpe, Caroline N David, Marcelo R Gonçalves, Guilhermo P Sesin, Leila B Moreira, Federal Univ Rio Grande Sul, Porto Alegre, Brazil; Flavio D Fuchs, Hosp Clinicas Porto Alegre, Porto Alegre Rs, Brazil

3:10 PM

Q & A

# Abstract Oral Session

## CH.AOS.484 - Pediatric/Congenital Oral Abstracts - Top Basic/Translational Science

#### 111AB

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Nikki G Posnack, Washington, DC

2:00 PM

Use of Glycoprotein IIb/IIIa Inhibition in Prevention of Blalock- Taussig Shunt Thrombosis in Pediatric Cardiac Surgery

**Breanna L Piekarski** , Jenna Rogers, David Zurakowski, Sitaram M Emani, Boston Children's Hosp, Boston, MA

2:10 PM

Q & A

2:15 PM

Placental Villous Infarcts Are a Marker of Impaired Fetal Growth and Poor Post-surgical Outcome in Infants With Critical Congenital Heart Defects

**Rebecca L Linn** , James W Gaynor, Children's Hosp of Philadelphia, Philadelphia, PA; Julie Moldenhauer, Children's Hosp of Philadelphia, PHiladelphia, PA; Jack Rychik, Children's Hosp of Philadelphia, Philadelphia, PA; Sunkyung Yu, Univ of Michigan, Ann Arbor, MI; Samuel I Parry, Univ of Pennsylvania, Philadelphia, PA; Susan C Nicolson, Children's Hosp of Philadelphia, Philadelphia, PA; Michal Elovitz, Univ of Pennsylvania, Philadelphia, PA; Rebecca Simmons, Nancy Burnham, Mark Johnson, Children's Hosp of Philadelphia, Philadelphia, PA; Matthew Sampson, ChilCS Mott Children's Hosp, Ann Arbor, MI; Hakon Hakonarson, Children's Hosp of Philadelphia, Philadelphia, PA; Mark W Russell, Univ of Michigan, Ann Arbor, MI

2:25 PM

Q & A

2:30 PM

MicroRNA-145-5p and MicroRNA-320a Encapsulated in Endothelial Microparticles Contribute to the Progression of Vasculitis in Acute Kawasaki Disease

**Hideyuki Nakaoka** , Keiichi Hirono, Seiji Yamamoto, Ichiro Takasaki, Med Univ of Toyama, Toyama, Japan; Kei Takahashi, Toho Univ Ohashi Medical Ctr, Tokyo, Japan; Mako Okabe, Toyama Univ, Toyama, Japan; Nariaki Miyao, Med Univ of Toyama, Toyama, Japan; Keijiro Ibuki, Pediatrics, Toyama, Japan; Sayaka Ozawa, Fukiko Ichida, Med Univ of Toyama, Toyama, Japan

2:40 PM

Q & A

2:45 PM

ST2 Is A Biomarker Of Pediatric Pulmonary Arterial Hypertension Severity And Clinical Worsening

**Megan Griffiths** , Johns Hopkins Univ, Baltimore, MD; Jun Yang, JOHNS HOPKINS HOSPITAL, Baltimore, MD; Melanie Nies, Johns Hopkins Univ, Baltimore, MD; Rachel L Damico, JOHNS HOPKINS, Baltimore, MD; Dunbar D IVY, Univ of Colorado, Aurora, CO; Wade Martin, Vanderbilt Univ, Nashville, TN; Bill Nichols, Michael Pauciulo, Cincinnati Children's Hosp, Cincinnati, OH; Allen D Everett, Johns Hopkins, Glenwood, MD

2:55 PM

Q & A

3:00 PM

De novo a **nd Recessive Forms of Congenital Heart Disease Have Distinct Genetic, Functional, and Phenotypic Landscapes**

**Martin Tristani-Firouzi** , Primary Children's Univ of Utah, Salt Lake City, UT; W. Scott Watkins, E. Javier Hernandez, Sergiusz Wesolowski, Brent W Bisgrove, Edwin Lin, Gordon Lemmon, Bradley L Demarest, Univ of Utah, Salt Lake City, UT; Daniel Bernstein, Stanford Univ, Palo Alto, CA; Wendy Chung, Columbia Univ, New York, NY; Bruce D Gelb, Icahn Sch of Med, New York, NY; Elizabeth Goldmuntz, Children's Hosp Philadelphia, Philadelphia, PA; Jane W Newburger, Children's Hosp Boston, Boston, MA; Christine E Seidman, Harvard Medical Sch, Boston, MA; Yufeng Shen, Columbia Univ, New York City, NY; H Joseph Yost, Univ of Utah, Salt Lake Cty, UT; Mark Yandell, Univ of Utah, Salt Lake City, UT

3:10 PM

Q & A

# Abstract Oral Session

## AT.AOS.462 - Russell Ross Memorial Lectureship in Vascular Biology

#### 126A

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Kerry-anne Rye, Sydney, Australia

2:00 PM

Moderator

Cynthia St Hilaire, Pittsburgh, PA

2:00 PM

Russell Ross Memorial Lectureship in Vascular Biology

Coleen A McNamara, Charlottesville, VA

2:25 PM

Q&A

2:30 PM

A Genome-wide CRISPR Interference Screen Reveals Novel Modulators of Hepatic LDL Receptor Expression

Geoffrey A Smith, Kevan M Shokat, **John S Chorba** , UCSF, San Francisco, CA

2:40 PM

Q & A

2:45 PM

ILRUN **, A Novel Plasma Lipid and CAD Locus in Humans, Regulates Lipoprotein Metabolism and Atherogenesis in Mice**

**Xin Bi** , Takashi Kuwano, Paul Lee, John S Millar, Raymond Soccio, Nicholas J Hand, Daniel J Rader, Univ of Pennsylvania, Philadelphia, PA

2:55 PM

Q & A

3:00 PM

Changes in Fatty Acid Composition by Elovl6 Ameliorates Pressure Overload-induced Cardiac Remodeling Through Maintenance of Mitochondrial Integrity in Cardiac Myocyte

**Sayaka Tadaki** , Hiroki Matsui, Hiroaki Sunaga, Nozomi Furukawa, Gunma Univ, Maebashi, Japan; Tatsuya Iso, Gunma Univ Graduate Sch Med, Maebashi Gunma, Japan; Norimichi Koitabashi, Gunma Univ Sch Med, Maebashi Gunma, Japan; Masahiko Kurabayashi, Gunma Univ Grad Sch of Med, Gunma, Japan; Tomoyuki Yokoyama, Gunma Univ, Maebashi, Japan

3:10 PM

Q & A

# Abstract Oral Session

## CE.AOS.541 - Wait, So Not All Inflammation Is Bad?

#### 120A

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Pilar Alcaide, Boston, MA

2:00 PM

Moderator

Marcin Wysoczynski, Louisville, KY

2:00 PM

Disruption Of Interleukin-18 Signaling Reduces Marker Of Myocardial T Cell Infiltration In A Mouse Model Of Hfpef

**Adolfo G Mauro** , Virginia Commonwealth Univ, Richmond, VA; Eleonora Mezzaroma, Virginia Commonwealth Univ, Henrico, VA; Pratyush Narayan, Salvatore Carbone, Virginia Commonwealth Univ, Richmond, VA; Antonio Abbate, Virginia Commonwealth Univ, Glen Allen, VA; Pilar Alcaide, Tufts Univ Sch Med, Boston, MA; Stefano Toldo, Virginia Commonwealth Univ, Glen Allen, VA

2:10 PM

Q & A

2:15 PM

Discovery of a Macrophage-Specific lncRNA That Regulates Macrophage Apoptosis and Atherosclerosis by Tethering the RNA-Binding Protein HuR

**Viorel Simion** , Brigham and Women's Hosp/Harvard Medical Sch, Boston, MA; Haoyang Zhou, Brigham and Women's Hosp /The Third Xiangya Hosp, Central South Univ, Changsha, Hunan, China, Boston, MA; Stefan Haemmig, Yevgenia Tesmenitsky, Mark W Feinberg, Brigham and Women's Hosp/Harvard Medical Sch, Boston, MA

2:25 PM

Q & A

2:30 PM

Cytokine Messenger RNA Degradation in Cardiomyocytes is Critical for Restraining Sterile Inflammation and Development of Heart Failure

**Shigemiki Omiya** , King's Coll London, London, United Kingdom; Kinya Otsu, Kings Coll London, London, United Kingdom

2:40 PM

Q & A

2:45 PM

Neutrophils and Eosinophils Are Endogenous Sources of IL-4 for Essential IL-4ralpha Activation That Promotes Angiogenesis and Infarct Repair Following Myocardial Infarction

Iqbal S Toor, Univ of Edinburgh, Edinburgh, United Kingdom; Jesuthas Ajendra, Dominik Ruckerl, Judith E Allen, Univ of Manchester, Manchester, United Kingdom; **Gillian A Gray** , Univ of Edinburgh, Edinburgh, United Kingdom

2:55 PM

Q & A

3:00 PM

Noncanonical Wnt Receptors Ror1/2 Are Induced by Fibroblast Activation and Protect the Injured Heart by Inhibiting Myofibroblast Recruitment of Proinflammatory Leukocytes

**Nicholas W Chavkin** , Soichi Sano, Ying Wang, Univ of Virginia, Charlottesville, VA; Karen Hirschi, Yale Sch Med, New Haven, CT; Kenneth Walsh, Univ of Virginia, Charlottesville, VA

3:10 PM

Q & A

# Cardiovascular Seminar

## WS.CVS.555 - Advancing Equity in Healthy Cardiovascular Aging

#### 117

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Barbara J Lutz, Hampstead, NC

2:00 PM

Moderator

Willie Mae M Abel, Salisbury, NC

2:00 PM

Impact of Social Determinants on Healthy Aging: Why Population Health Matters

George A Mensah, Bethesda, MD

2:18 PM

Impact of Neighborhood on Healthy Aging

Michele K Evans, Baltimore, MD

2:54 PM

Prevention Strategies for Healthy Aging

Michelle C. Odden, Palo Alto, CA

# Cardiovascular Seminar

## MP.CVS.164 - Cardiac Remodeling Is All About Metabolism

#### 120C

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Bradford G. Hill, Louisville, KY

2:00 PM

Moderator

Wang Wang, Seattle, WA

2:00 PM

Substrate Metabolism in Heart Hypertrophy

Rong Tian, Seattle, WA

2:10 PM

Q&A

2:15 PM

Metabolite Signaling in Cardiovascular Tissues

Mathias Mericskay, Chatenay-Malabry, France

2:25 PM

Q&A

2:30 PM

Oncometabolic Phenotype of the Failing Heart

Anja Karlstaedt, Houston, TX

2:40 PM

Q&A

2:45 PM

GPCR Regulation of Metabolism in the Heart

Iain Scott

2:55 PM

Q&A

3:00 PM

Metabolic Regulation in Cardiomyopathy

Konstantinos Drosatos, Philadelphia, PA

3:10 PM

Q&A

# Cardiovascular Seminar

## ST.CVS.87 - Cardiovascular Disease and Intracranial Aneurysms?

#### 105AB

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Sameer A Ansari, CHICAGO, IL

2:00 PM

Moderator

Philip M MEYERS, New York, NY

2:00 PM

Cardiovascular Pathogenesis, Genetics, and Risk Factors in Intracranial Aneurysm Development

Muhammad Shazam Hussain, Cleveland, OH

2:15 PM

Aneurysmal Subarachnoid Hemorrhage and Takotsubo Cardiomyopathy

Andrew Naidech, Chicago, IL

2:30 PM

Management of Cardioembolic Mycotic and Myxomatous Intracranial Aneurysms

Kristine A Blackham, Cleveland, OH

2:45 PM

Technological Evolution in the Endovascular Management of Intracranial Aneurysms

Justin Fraser, Lexington, KY

3:00 PM

Discussion

# Cardiovascular Seminar

## GE.CVS.364 - Clinical Dilemmas in Cardiovascular Genetics

#### 120B

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Neal Lakdawala, Boston, MA

2:00 PM

Moderator

Steven Lubitz, Boston, MA

2:10 PM

Moderated Discussion

2:15 PM

It's 2019: Clinical Genetic Testing is Appropriate for DCM

Kristina Haugaa, Oslo, Norway

2:25 PM

Moderated Discussion

2:30 PM

Genetic Testing is Clinical Standard of Care for LQTS

Lee L Eckhardt, Madison, WI

2:40 PM

Moderated Discussion

2:45 PM

Clinician Responsibilities to Communicate Genetic Test Results; Before and After Proband Death

Jodie Ingles, Sydney, Australia

2:55 PM

Moderated Discussion

3:00 PM

Panel Discussion

# Cardiovascular Seminar

## IN.CVS.395 - Complex and High Risk Intervention

#### 107AB

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Peter James Mason, Milwaukee, WI

2:00 PM

Moderator

Binita Shah, New York, NY

2:00 PM

Optimal Approach to Chronic Total Occlusions

Emmanouil S BRILAKIS, Minneapolis, MN

2:12 PM

Case of a Patient With a Chronic Total Occlusion

Marwan Saad, Little Rock, AR

2:16 PM

Severe Calcification: Preparing for Success!

Ali E Denktas, Houston, TX

2:28 PM

Case of a Patient With a Severely Calcified Artery

Celina Mei Yong, San Carlos, CA

2:32 PM

Left Main Disease: The Ultimate Bifurcation!

Gregory DUCROCQ, Paris, France

2:44 PM

Case of a Patient With Severe Left Main Disease

Waleed T Kayani, Houston, TX

2:48 PM

Panel Discussion

# Cardiovascular Seminar

## AC.CVS.452 - Conundrums in the Use of Anti-platelet and Anti-thrombotic Therapy

#### 103A

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

KELLY EPPS, Washington, DC

2:00 PM

Moderator

Dominick J Angiolillo, Jacksonville, FL

2:00 PM

DAPT, DAT or TAT: What is the Ideal Management?

Matthew W Sherwood, Arlington, VA

2:12 PM

Case of a Patient With ACS Who is s/p PCI, and Requires Oral Anticoagulation

Yashasvi Chugh, New York, NY

2:17 PM

Panel Discussion

2:26 PM

Duration of DAPT: Short, Long or Indefinite?

Roxana Mehran, New York, NY

2:42 PM

Panel Discussion

2:51 PM

Cangrelor: What is it Good for?

Usman Baber, New York, NY

3:03 PM

Case of a Patient Treated With Cangrelor During a PCI

Barbara L Lawson, Richmond, VA

3:07 PM

Panel Discussion

# Cardiovascular Seminar

## SA.CVS.475 - Endovascular Strategies in Thoracic Aortic Surgery

#### 109AB

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Thomas Gleason, Pittsburgh, PA

2:00 PM

Moderator

Jean Marie Ruddy

2:00 PM

Endovascular Type A Repair: Will This change Our Surgical Strategy for the Arch/Descending Aorta During the Primary Operation?

Wilson Szeto, PA

2:15 PM

Second Stage Procedure After FET in Patients With Connective Tissue Disorders: TEVAR vs. Open Surgery

Joseph E Bavaria, Philadelphia, PA

2:30 PM

Strategies to Treat Endoleaks With the Expanding Descending Aorta in Chronic Type B Dissections

A Claire P Watkins, Stanford, CA

2:45 PM

Open TAAA Surgery After Previous Endovascular Repair: Technique and Who Will Be Able to Do in the Future?

Chad Hughes

3:00 PM

Risk Stratifying Uncomplicated Type B Dissections: Who Should Have a TEVAR Prophylactically?

Dominik Fleischmann, Stanford, CA

# Cardiovascular Seminar

## AT.CVS.239 - Extracellular Vesicles in Cardiovascular Disease: The Good and the Bad

#### 126B

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Elena Aikawa, Boston, MA

2:00 PM

Moderator

Susmita SAHOO, New York, NY

2:00 PM

The Role of Extracellular Vesicles in Cardiovascular Calcification

Elena Aikawa, Boston, MA

2:10 PM

Q&A

2:15 PM

Exosomes in Diagnostic and Therapeutics in Cardiovascular Medicne

Susmita SAHOO, New York, NY

2:25 PM

Q&A

2:30 PM

Therapeutic Potential of Extracellular Vesicles

Stella Kourembanas, Boston, MA

2:40 PM

Q&A

2:45 PM

Requirement for Studies of Extracellular Vesicles

Kenneth W Witwer, Baltimore, MD

2:55 PM

Q&A

3:00 PM

Panel Discussion

# Cardiovascular Seminar

## IM.CVS.379 - Imaging Acute Chest Pain

#### 108B

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Garth Beache

2:00 PM

Moderator

Jill Jacobs, New York, NY

2:00 PM

Imaging Role in Integrated Chest Pain Unit

Michael Salerno, Charlottesville, VA

2:15 PM

Lessons From Multi-center Trials

Pamela Woodard, St Louis, MO

2:30 PM

CCTA Functional Assesment of Ischemia

Carlo N, DeCecco, Atlanta, GA

2:45 PM

NeWer Cardiac CTA Perspectives

Udo Hoffmann, Boston, MA

3:00 PM

Discussion

# Cardiovascular Seminar

## HY.CVS.435 - It's Not Just in your Head: The Role of Hypertension Control in Preserving Cognitive Function.

#### 108A

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Rebecca F Gottesman, Bethesda, MD

2:00 PM

Moderator

Ilya Nasrallah, Philadelphia, PA

2:00 PM

Epidemiology of Hypertension and Cognitive Impairment

Kristine Yaffe, San Francisco, CA

2:25 PM

Can We Prevent Declines in Cognitive Impairment:The SPRINT-MIND Study

Jeff Williamson, Winston-Salem, NC

2:50 PM

Panel Participant

Kristine Yaffe, San Francisco, CA

2:50 PM

Panel Participant

Jeff Williamson, Winston-Salem, NC

2:50 PM

Panel Participant

Rebecca F Gottesman, Bethesda, MD

2:50 PM

Panel Participant

Ilya Nasrallah, Philadelphia, PA

# Cardiovascular Seminar

## CA.CVS.101 - Leveraging Social Media for Learning/Networking/Advocating in Cardiovascular Science

#### 121C

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Facilitator

Sean M Wu, Stanford, CA

2:00 PM

Facilitator

Taben M Hale, Phoenix, AZ

2:00 PM

Facilitator

Alex Perrow Carll, Louisville, KY

2:00 PM

Facilitator

Cynthia St Hilaire, Pittsburgh, PA

2:00 PM

Facilitator

Milka Koupenova, Worcester, MA

# Cardiovascular Seminar

## HF.CVS.406 - LVADs and the Clinical Dilemmas that Flow our Way!

#### Terrace Ballroom IV

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Ravi Dhingra, Madison, WI

2:00 PM

Moderator

Evgenij Potapov, Berlin, Germany

2:00 PM

Predict Before or Treat Later: RV Failure

Michael Kiernan, Boston, MA

2:15 PM

Optimal BP and INR Targets to Prevent Stroke in LVAD Patients

Salpy Pamboukian, Birmingham, AL

2:30 PM

Lateral Thoracotomy for LVAD Implant: When and Why

Christopher Salerno, Stanford, CA

2:45 PM

Roundtable Discussion: Intentional Networking

Michael Kiernan, Boston, MA

2:45 PM

Roundtable Discussion: Intentional Networking

Salpy Pamboukian, Birmingham, AL

2:45 PM

Roundtable Discussion: Intentional Networking

Christopher Salerno, Stanford, CA

# Cardiovascular Seminar

## CM.CVS.415 - Managing Cardiovascular Risk in Diabetes: Ask the Experts and Challenging Cases

#### 204AB

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Muthiah Vaduganathan, Boston, MA

2:05 PM

Moderator

Ravi Patel, Chicago, IL

2:10 PM

Panel Participant

Erin D Michos, Baltimore, MD

2:18 PM

Panel Participant

Prakash Deedwania, Fresno, CA

2:22 PM

Panel Participant

Anand Rohatgi, Dallas, TX

2:26 PM

Panel Participant

Andrew Patrick Ambrosy, San Francisco, CA

2:30 PM

Q & A

# Cardiovascular Seminar

## PR.CVS.217 - Optimizing Adherence to CVD Treatment Regimens: Best Practices from Behavioral Medicine and Impact of Health Literacy

#### 204C

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Ian M Kronish, New York, NY

2:00 PM

Moderator

Susan A Everson-Rose, Minneapolis, MN

2:00 PM

Case Presentation: Adherence to CVD Medications in Patient With Low Health Literacy

Lena Mathews, Baltimore, MD

2:03 PM

Developing and Implementing Multi-Level Behavior Change Interventions to Improve Adherence and Cardiovascular Outcomes

Hayden Bosworth, Durham, NC

2:18 PM

Addressing Health Literacy Can Improve Adherence and Cardiovascular Care

Crystal N CENE, Durham, NC

2:33 PM

Improving Adherence in CVD Patients: A Role for Cardiac Rehabilitation

Todd M Brown, Birmingham, AL

2:48 PM

Use of Digital Health Technologies to Foster Adherence and Health Literacy

Angela Pfammatter, Chicago, IL

3:03 PM

Q&A/Discussion

# Cardiovascular Seminar

## EP.CVS.527 - Precision Lifestyle Medicine in Cardiovascular and Multimorbidity Prevention and Control

#### 202AB

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Jun Ma, Chicago, IL

2:00 PM

Moderator

Elizabeth A Jackson, Birmingham, AL

2:00 PM

Just-in-time Adaptive Interventions (JitAIs) - May the Force Be With You forWeight Loss Management

Angela Pfammatter, Chicago, IL

2:30 PM

What is So Smart About Smart Trials? Implications for Physical Activity Interventions

Tavis Campbell, AB, Canada

2:45 PM

An Experimental Medicine Approach to Studying Neural Mechanisms Underlying Integrated Behavior Therapy for Comorbid Obesity and Depression

Jun Ma, Chicago, IL

3:00 PM

Panel Discussion

# Cardiovascular Seminar

## EA.CVS.182 - Should I Refer My Patient for the Newest Technologies in Arrhythmia Management? What's Ready for Prime Time and What's Still Too Risky?

#### 113BC

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Andrea M Russo, Camden, NJ

2:00 PM

Moderator

Phillip S Cuculich, Saint Louis, MO

2:00 PM

Who's a Candidate for Leadless Pacing and Defibrillation? Short and Long Term Risks and Benefits

Niek Beurskens, Amsterdam, Netherlands

2:08 PM

Noninvasive Radioablation - Is it Ready for Prime Time?

Amin Al-Ahmad, Austin, TX

2:16 PM

Imaging in the EP Lab: Does Real-time MRI, CT, Echo, Virtual Imaging Integration Add Anything?

Henry R. Halperin, Baltimore, MD

2:24 PM

What's Newest and Hottest in Ventricular Ablation

Francis Marchlinski, Philadelphia, PA

2:32 PM

What's Newest and Hottest (Coldest) in Atrial Ablation Technologies.

Vivek Reddy, New York, NY

2:40 PM

What's New in Wearable Cardioverter Defibrillators? Can Newer Devices Improve Compliance and Safety?

Yong-mei Cha, Rochester, MN

2:48 PM

Should Everyone Attempt His Bundle Pacing? Short- and Long-Term Outcomes

Gopi Dandamudi, Zionsville, IN

2:56 PM

CRT Nonresponse: Do I Tell My Patients to Accept This or Seek New Technologies?

Niraj Varma, Cleveland, OH

3:04 PM

Device Follow-up: Can We Do Away With Clinic Visits With Advances in Remote Monitoring?

Suneet Mittal, New York, NY

3:12 PM

Q & A

# Cardiovascular Seminar

## CH.CVS.446 - State-of-the-Art Approaches to Evaluation and Treatment of Coarctation of the Aorta

#### 112AB

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Annette ANSONG, Fairfax, VA

2:00 PM

Moderator

Sarah Pickard, Boston, MA

2:00 PM

Prenatal Assessment of Coarctation of the Aorta

Bhawna Arya, Seattle, WA

2:15 PM

Diagnosis and Treatment of Recoarctation in Hypoplastic Left Heart Syndrome

Tacy E Downing, Washington, DC

2:30 PM

Vascular Evaluation After Coarctation of the Aorta Treatment

Ashwin Prakash, Boston, MA

2:45 PM

Imaging of abnormal Flow Dynamics in Coarctation

Uyen Truong, Aurora, CO

3:00 PM

Recognition and Management of Hypertension Across Stages of Coarctation

Joseph Mahgerefteh, Bronx, NY

# Cardiovascular Seminar

## MP.CVS.252 - The Exposome and Cardiometabolic Health

#### 119AB

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Daniel J Conklin, Louisville, KY

2:00 PM

Moderator

Kristin I Stanford, Columbus, OH

2:00 PM

Linking Environmental Exposures With Cardiometabolic Disease

Arden Pope, Provo, UT

2:10 PM

Q&A

2:15 PM

Environmental Exposures and CV Health

Loren E Wold, Columbus, OH

2:25 PM

Q&A

2:30 PM

Mechanisms of Vascular Inflammation and Cardiometabolic Health in Indigenous Peoples

Matthew J. Campen, Albuquerque, NM

2:40 PM

Q&A

2:45 PM

Insulin Resistance in Humans With Environmental Exposures

Aruni Bhatnagar, Louisville, KY

2:55 PM

Q&A

3:00 PM

Insulin Resistance in Animal Studies With Air Pollution Exposures

Petra Haberzettl, Louisville, KY

3:10 PM

Q&A

# Cardiovascular Seminar

## VA.CVS.374 - The Latest and Best in PVD Interventions: Co-Sponsored by Circulation: Cardiovascular Interventions

#### 103B

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Sunil V Rao, Durham, NC

2:00 PM

Fake News or Real? Safety Concerns With Paclitaxel-coated Balloons and Stents

Robert Kevin Rogers, Aurora, CO

2:10 PM

Discussion

2:15 PM

The Last Frontier? Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension

Hiromi Matsubara, Okayama, Japan

2:25 PM

Discussion

2:30 PM

Venous Interventions for DVT and PE: What Are We Waiting for?

Riyaz Bashir, Philadelphia, PA

2:40 PM

Discussion

2:45 PM

Down Below the Knee: What's Coming Up?

William S Jones, Durham, NC

2:55 PM

Discussion

3:00 PM

Stragglers No More: Emerging Evidence for Aortic EnDografts

Shirling Tsai, Dallas, TX

3:10 PM

Discussion

2:00 PM

Panel Participant

Robert ROGERS, Aurora, CO

2:00 PM

Panel Participant

Jinnette Dawn Abbott, Providence, RI

2:00 PM

Panel Participant

Dharam J Kumbhani, Dallas, TX

2:00 PM

Panel Participant

Scott Kinlay, West Roxbury, MA

2:00 PM

Panel Participant

Sanjay Misra, Rochester, MN

# Cardiovascular Seminar

## LF.CVS.413 - Understanding the Link Between Adiposity and Heart Failure

#### 201AB

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Jarett D Berry, Dallas, TX

2:00 PM

Moderator

Marie-Eve Piche, Quebec, QC, Canada

2:00 PM

Case Presentation: A Middle-aged Adult With Morbid Obesity and Minimal Other Risk Factors Who Develops HFpEF

Carine Hamo, Baltimore, MD

2:02 PM

Metabolic and Hormonal Alterations in Obesity: Implications for Heart Failure Risk

Milton Packer, Dallas, TX

2:14 PM

Q&A

2:16 PM

Adipose Tissue Distribution vs BMI for Informing Heart Failure Risk in Obesity

Ian J Neeland, Dallas, TX

2:28 PM

Q&A

2:30 PM

Myocardial Injury, Fibrosis and Heart Failure in Obesity

Chiadi Ericson Ndumele, Baltimore, MD

2:42 PM

Q&A

2:44 PM

Metabolic Imaging to Assess Heart Failure Risk in Obesity

Linda R Peterson, St Louis, MO

2:56 PM

Q&A

2:58 PM

Sarcopenic Obesity and Heart Failure

Stefan D Anker, Berlin, Germany

3:10 PM

Q&A

# Cardiovascular Seminar

## EA.CVS.73 - What Does the 2019 Focused Update of AF Guidelines Teach Us About Anti-Coagulation Challenges?

#### Heart Theater

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Cynthia Tracy, Washington, DC

2:00 PM

Moderator

Joshua N Goldstein, Boston, MA

2:00 PM

What Anti-Coagulation Agents Are Safe in Patients With End-Stage Kidney Disease?

Michael D Ezekowitz, Villanova, PA

2:12 PM

Management of Anti-Coagulation During Elective Surgery

Jennifer M Wright, Madison, WI

2:24 PM

Oral Anti-Coagulation versus Left Atrial Appendage Occlusion for Stroke Prevention

D.J. Lakkireddy, Kansas City, KS

2:36 PM

My AF Patient Just Underwent PCI: Triple versus Double Therapy

Christopher P Cannon, Boston, MA

2:48 PM

Anti-Coagulation Management Before and After Cardioversion

Sana M Al-Khatib, Durham, NC

3:00 PM

Panel Discussion

# Early Career

## QU.EC.313 - AHA's Got Talent: Perfecting Your 3-Minute Elevator Speech

#### 201C

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Colleen K McIlvennan, Aurora, CO

2:00 PM

Moderator

Kori S Zachrison, Boston, MA

2:00 PM

Talk Nerdy To Me

Tony Tsai, UT

2:00 PM

judge/facilitator

John Spertus, Kansas City, MO

2:00 PM

judge/facilitator

Lee H Schwamm, Boston, MA

2:00 PM

judge/facilitator

Rashmee Shah, Salt Lake City, UT

2:00 PM

judge/facilitator

Brahmajee Nallamothu, Ann Arbor, MI

# Hall

## HT.07 - Beyond Wearables: Life, Health, Sensor Fusion & Deeper Medicine

#### Health Innovation Pavilion, Heart Hub, Science and Technology Hall, Level 2

### Sunday, November 17, 2019, 2:00 PM - 2:50 PM

2:00 PM

Invited Presenter

Mathieu LeTombe, MA

2:00 PM

Invited Presenter

David Rhew, CA

# Hall

## EA.HT.67 - Separating the Wheat from the Chaff - the EP Approach to Nonspecific Symptoms

#### 113A

### Sunday, November 17, 2019, 2:00 PM - 3:00 PM

2:00 PM

Moderator

Brian Olshansky, Iowa City, IA

2:00 PM

Moderator

Marye J Gleva, Saint Louis, MO

2:00 PM

I Have POTS. Now What?

Satish R Raj, Calgary, AB, Canada

2:08 PM

Palpitations

Rakesh Gopinathannair, Louisville, KY

2:16 PM

Dizziness Lightheadedness

Suzanne Feigofsky, Gainesville, FL

2:24 PM

Transient Loss of Consciousness

Zachary Goldberger, Seattle, WA

2:32 PM

Inappropriate Sinus Tachycardia

Riccardo Cappato, San Donato Milanese, Italy

2:40 PM

Placebo Effects in Cardiology

John Mandrola, Louisville, KY

2:48 PM

Q & A

# Hall

## EP.HT.04 - Why and How to Implement Lifestyle and Risk Factor Modification for AF in Your Practice – An Expert Panel Discussion

#### EP Central

### Sunday, November 17, 2019, 2:00 PM - 2:45 PM

2:00 PM

Moderator

Mina K Chung, Cleveland, OH

2:00 PM

Panel Participant

Jose A Joglar Sr., Dallas, TX

2:00 PM

Panel Participant

Prashanthan Sanders, Adelaide, Australia

2:00 PM

Panel Participant

Lin Yee Y Chen, Minneapolis, MN

2:00 PM

Panel Participant

Quinn R Pack, Ellington, CT

2:40 PM

Panel Discussion

# Joint Sessions

## IN.JS.1616 - Global Roundtable: Interventional Treatments from Around the Globe (French Society of Cardiology, Heart and Health Foundation of Turkey, Israel Heart Society and Japanese Society of Pediatric Cardiology and Cardiac Surgery)

#### 121A

### Sunday, November 17, 2019, 2:00 PM - 3:15 PM

2:18 PM

Percutaneous Therapies for the Mitral Valve : Where Do We Stand?

Ali Oto, Ankara, Turkey

2:36 PM

Risk Analysis of Percutaneous Atrial Septal Closure, Especially Cardiac Erosion from JPIC Registry

Hisashi Sugiyama, Tokyo, Japan

2:54 PM

Panel Discussion

# Moderated Digital Posters

## GE.MDP39 - Cardiovascular Genomic Medicine

#### Moderated Posters 5, Science and Technology Hall

### Sunday, November 17, 2019, 2:10 PM - 3:00 PM

2:10 PM

Moderator

Allison Cirino, Boston, MA

2:10 PM

Whole Exome Sequencing in a Cardiovascular Cohort Identifies Previously Undiagnosed Monogenic Cardiovascular Diseases

**Jawan W Abdulrahim** , Lydia C Kwee, Duke Univ, Durham, NC; Fawaz Alenezi, Duke Univ Medical Ctr, Durham, NC; Aris Baras, Regeneron Pharmaceuticals, Tarrytown, NY; Teminioluwa Ajayi, Vanderbilt Univ Medical Ctr, Nashville, TN; Christopher L Holley, Duke Univ Sch of Med, Durham, NC; Robert Walker McGarrah III, James Patrick Daubert, Lauren K Truby, Sreekanth Vemulapalli, Duke Univ Medical Ctr, Durham, NC; Andrew Wang, Duke Univ Medical Ctr, Chapel Hill, NC; Svati H Shah, Duke Univ Medical Ctr, Hillsborough, NC

2:15 PM

Q & A

2:20 PM

High Clinical False-Negative Rate of Direct-to-Consumer Genetic Screening for Familial Hypercholesterolemia

**Tom E Callis** , Edward D Esplin, Eden Haverfield, Rebecca Truty, Matteo Vatta, Robert L Nussbaum, Invitae, San Francisco, CA

2:25 PM

Q & A

2:30 PM

Predicted Loss of Function Variants in Long QT Genes are Not Phenotypically Deterministic

**Jonathan Z Luo** , Dustin Hartzel, Cassandra Hartle, Geisinger, Danville, PA; Tooraj Mirshahi, Geisinger, Danville

2:35 PM

Q & A

2:40 PM

**Comparative 5-year Outcomes in Non-ischemic Dilated Cardiomyopathy (NIDC) Patients With TITIN (** TTN **) Gene Truncating Variant (tv) Mutations**

**Jeffrey Lance Anderson** , Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT; Victoria Jacobs, Intermountain Medical Ctr, Salt Lake Cty, UT; G Bryce Christensen, Helaman Escobar, Intermountain Healthcare, Salt Lake City, UT; Benjamin D Horne, Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT; Kia Afshar, Virginia B Hebl, Kirk Ute Knowlton, Intermountain Medical Ctr, Salt Lake City, UT; Joseph B Muhlestein, Intermountain Medical Ctr; Univ of Utah, Salt Lake City, UT; John F Carlquist, Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT; Lincoln Nadauld, Intermountain Healthcare, Salt Lake City, UT

2:45 PM

Q & A

2:50 PM

Genome-Wide Association Analysis of Cardiac Magnetic Resonance Imaging in >24,000 Participants Reveals 24 Novel Loci and Shared Genetic Basis With Cardiomyopathies

**James P Pirruccello** , Massachusetts General Hosp, Boston, MA; Minxian Wang, Broad Inst of MIT and Harvard, Cambridge, MA; Mark Chaffin, Broad Inst, Cambridge, MA; Sekar Kathiresan, Verve Therapeutics, Cambridge, MA; Krishna Aragam, Broad Inst, Cambridge, MA

2:55 PM

Q & A

# Moderated Digital Posters

## CA.MDP42 - Myocardial Ischemia/Reperfusion Injury

#### Moderated Posters 6, Science and Technology Hall

### Sunday, November 17, 2019, 2:10 PM - 3:00 PM

2:10 PM

Moderator

Lorrie A Kirshenbaum, Winnipeg, MB, Canada

2:10 PM

Cardiac Warburg Effect is Controlled by Single Serine on TSC2 and Protects Against Ischemia-Reperfusion Injury

**Christian Ulrich Oeing** , Seungho Jun, Brittany Dunkerly-Eyring, Sumita Mishra, Johns Hopkins Medical Insts, Baltimore, MD; Usman Tahir, Beth Israel Deaconess Medical Ctr, Boston, MA; Guangshuo Zhu, Gizem Keceli, Johns Hopkins Medical Insts, Baltimore, MD; Robert Gerszten, Beth Israel Deaconess Medical Ctr, Boston, MA; Mark Ranek, Nazareno Paolocci, David Kass, Johns Hopkins Medical Insts, Baltimore, MD

2:15 PM

Q & A

2:20 PM

Rapamycin Protects Against Myocardial Ischemia/Reperfusion Injury in Diabetic Mice Through Stat3-mir17/92 Signaling and Suppression of Prolyl Hydroxylase

Arun Samidurai, Sean Roh, Fadi N Salloum, Rakesh C Kukreja, **Anindita Das** , Virginia Commonwealth Univ, Richmond, VA

2:25 PM

Q & A

2:30 PM

Myocardial Ischemia Increases the Expression of Cardiomyocyte Krüppel-Like Factor 5 That Accounts for Ceramide Biosynthesis, Suppression of miR-30 Expression and Systolic Dysfunction

**Matthew Hoffman** , Ioannis D Kyriazis, Walker Lyons, Sudarsan Rajan, Erhe Gao, Mohsin Khan, Lewis Katz Sch of Med at Temple Univ, Philadelphia, PA; Craig Selzman, Univ of Utah Sch of Med, Salt Lake City, UT; Stavros G Drakos, Univ of Utah Sch of Med, Salt Lake Cty, UT; Konstantinos Drosatos, Lewis Katz Sch of Med at Temple Univ, Philadelphia, PA

2:35 PM

Q & A

2:40 PM

Ccn5 Gene Therapy Reduces Myocardial Infarction Size and Improves Contractility in Ischemic Cardiomyopathy

Dongtak Jeong, Jimeen Yoo, Min Ho Song, Sarah M Gubara, Michael G Katz, Icahn Sch of Med at Mount S, New York, NY; Woo Jin Park, Gwangju Inst Sci Tech, Gwangju, Korea, Republic of; **Anthony Fargnoli** , Icahn Sch of Med at Mount S, New York, NY

2:45 PM

Q & A

2:50 PM

Sestrin2-mTORC1 Signaling Mediates Myocardial Endoplasmic Reticulum Stress During Ischemia/reperfusion

**Xuan Li** , Univ of Mississippi Medical Ctr, Jackson, MS; Di Ren, Jingwen Zhang, Jia Liu, Ji Li, Univ of South Florida, Tampa, FL

2:55 PM

Q & A

# Moderated Digital Posters

## HF.MDP30 - New Ways to Risk Stratify Patients with HF and Cardiomyopathy

#### Moderated Posters 2, Science and Technology Hall

### Sunday, November 17, 2019, 2:10 PM - 3:00 PM

2:10 PM

Moderator

Lauren Cooper, Falls Church, VA

2:10 PM

Prognostic Value of Serum N-terminal Pro-brain Natriuretic Peptide for Sudden Cardiac Death Prediction in Patients With Hypertrophic Cardiomyopathy

**Guixin Wu** , State Key Lab of Cardiovascular Disease, Fuwai Hosp, Natl Ctr for Cardiovascular Diseases, Chinese Acad of Medical Sciences and Peking Union Medical Coll, Beijing, China; Yubao Zou, Natl Clinical Res Ctr for Cardiovascular Disease , Fuwai Hosp, Natl Ctr for Cardiovascular Diseases, Chinese Acad of Medical Sciences and Peking Union Medical Coll, Beijing, China; Jie Liu, State Key Lab of Cardiovascular Disease, Fuwai Hosp, Natl Ctr for Cardiovascular Diseases, Chinese Acad of Medical Sciences and Peking Union Medical Coll, beijing, China; Limei Wang, Xiaolu Sun, Lianming Kang, Natl Clinical Res Ctr for Cardiovascular Diseases, Fuwai Hosp, Natl Ctr for Cardiovascular Disease, Chinese Acad of Medical Science and Peking Union Medical Coll, Beijing, China; Lei Song, Jizheng Wang, State Key Lab of Cardiovascular Disease, Fuwai Hosp, Natl Ctr for Cardiovascular Diseases, Chinese Acad of Medical Sciences and Peking Union Medical Coll, Beijing, China

2:15 PM

Q & A

2:25 PM

Q & A

2:30 PM

Novel Protein Biomarkers Associated With Dyssynchrony in Heart Failure

**Christian Vestman** , Karolinska Univ Hosp, Stockholm, Sweden; Iziah Sama, Univ Medical Ctr Groningen, Groningen, Netherlands; Adriaan Voors, Univ Medical Ctr Groningen, Groningen, Germany; Lina Benson, Gianluigi Savarese, Karolinska Instt, Stockholm, Sweden; Lars Lund, Marcus Stahlberg, Karolinska Univ Hosp, Stockholm, Sweden

2:35 PM

Q & A

2:40 PM

Patient Reported HF Health Status and Gender: Data From the AdaptResponse Trial

**Bruce L Wilkoff** , Cleveland Clinic, Chagrin Falls, OH; David H Birnie, Univ of Ottawa Heart Inst, Ottawa, ON, Canada; Mikhael F El-Chami, Emory Univ, Atlanta, GA; Vidal Essebag, McGill Univ Health Ctr, Montreal, QC, Canada; Michael R Gold, Medical Univ of South Carolina, Charleston, SC; Ahmad S Hersi, King Saud Univ, Riyadh, Saudi Arabia; Charan Kantipudi, Piedmont Heart Inst, Atlanta, GA; Kengo F Kusano, Natl Cerebral and Cardiovascular Ctr, Osaka, Japan; Christophe Leclercq Sr., CHU Pontchaillou, Rennes, France; Bela Merkely, Semmelweis Univ, Budapest, Hungary; Wilfried Mullens, Ziekenhuis Oost Limburg, Genk, Belgium; Balbir Singh Sr., Medanta, The Medicity Hosp, Gurgaon, India; Bart EW Gerritse, Sandra Jacobs, Medtronic Bakken Res Ctr, Maastricht, Netherlands; Gerasimos Filippatos, Athens Univ Hosp Attikon, Athens, Greece

2:45 PM

Q & A

2:50 PM

Derivation and Validation of the Bridge to Transplantation With Left Ventricular Assist Device Score for One Year Mortality After Heart Transplantation. The Btt-lvad-score

**Alexis K Okoh** , RWJ Barnabas Health NBIMC, Newark, NJ; Setri Fugar, Rush Univ Medical Ctr, Chicago, IL; Ebru Ozturk, Molly Schultheis, RWJ Barnabas Health NBIMC, Newark, NJ; Mark Russo, Columbia Univ, New York, NY; Mark Zucker, Newark Beth Israel Medical Ctr, Newark, NJ; Margarita Camacho, RWJ Barnabas Health NBIMC, Newark, NJ

2:55 PM

Q & A

# Moderated Digital Posters

## AT.MDP36 - Novel Roles of Lipoprotein Modifying Pathways

#### Moderated Posters 4, Science and Technology Hall

### Sunday, November 17, 2019, 2:10 PM - 3:00 PM

2:10 PM

Moderator

Thomas A Vallim, Los Angeles, CA

2:10 PM

Lipoprotein (a) Cellular Uptake ex-vivo and Hepatic Capture in-vivo is Insensitive to Pcsk9 Inhibition With Alirocumab

**KEVIN CHEMELLO** , Gilles Lambert, Inserm UMR DéTROI, Sainte Clotilde, Réunion

2:15 PM

Q & A

2:20 PM

Expression and Function of Pcsk9 in Human Pancreatic Beta Cells

**Stephane Ramin-Mangata** , Gilles Lambert, Lab Inserm UMR DéTROI, Sainte Clotilde, Réunion

2:25 PM

Q & A

2:30 PM

Sterol Carrier Protein-2 (SCP2) Deficiency Attenuates Western Diet (WD)-Induced Hyperlipidemia, Hepatic Steatosis and Bile Acid Composition in LDLR-/- Mice

Jing Wang, Virginia Commonwealth Universi, Richmond, VA; Paul Yannie, Genta Kakiyama, Hunter McGuire VA Medical Ctr, Richmond, VA; Matthew Halquist, William Korzun, **Shobha Ghosh** , Virginia Commonwealth Universi, Richmond, VA

2:35 PM

Q & A

2:40 PM

Reduced HDL Due to Hypertriglyceridemia Does Not Affect Atherosclerosis Regression

**Tatjana Josefs** , Debapriya Basu, NYU Sch of Med, New York, NY; Tomas Vaisar, Univ Washington, Seattle, WA; Jenny E Kanter, Univ of Washington, Seattle, WA; Jay Heinecke, UW Med, Seattle, WA; Karin Bornfeldt, Univ of Washington, Seattle, United States Minor Outlying Islands; Ira J Goldberg, New York Univ, New York, NY; Edward A Fisher, NYU Langone Medical Ctr, New York, NY

2:45 PM

Q & A

2:55 PM

Q & A

# Moderated Digital Posters

## NR.MDP33 - Power to the Patients: Improving Quality of Life with Monitoring Tools

#### Moderated Posters 3, Science and Technology Hall

### Sunday, November 17, 2019, 2:10 PM - 3:00 PM

2:10 PM

Exercise Effects Quality of Life, Depression, and Anxiety After an ICD

**Cynthia M Dougherty** , Robert L Burr, Univ Washington Sch Nursing, Seattle, WA; Peter J. Kudenchuk, Univ of Washington, Seattle, WA; Robb Glenny, Univ Washington Sch Med, Seattle, WA

2:15 PM

Q & A

2:20 PM

Mobile ECG Self-Monitoring and Health-Related Quality of Life in Patients With Atrial Fibrillation

**Billy A Caceres** , Suzanne Bakken, Columbia Univ, New York, NY; Kathleen T Hickey, Columbia Univ, Trumbull, CT; Haomiao Jia, Columbia Univ, New York, NY

2:25 PM

Q & A

2:30 PM

Improved Quality of Life During Therapy Guided by Ambulatory Hemodynamic Monitoring

**Lisa D. Rathman** , Lancaster General Health/PENN Med, Lancaster, PA; Robert C. Bourge, The Univ of Alabama at Birmingham, Birmingham, AL; Akshay S Desai, Brigham Womens Hosp, Boston, MA; J. Thomas Heywood, Scripps Health, La Jolla, CA; Philip Adamson, Abbott, Austin, TX; Marie-Elena Brett, Abbott, Burlington, MA; Lynne W. Stevenson, Vanderbilt Univ Medical Ctr, Nashville, TN

2:35 PM

Q & A

2:40 PM

**Recurrent Atrial Fibrillation/flutter Detection After Ablation or Cardioversion Using the Alivecor** ® **Kardiamobile Device: Iheart Results**

**Isaac L Goldenthal** , Columbia Univ Irving Medical Ctr, New York, NY; Robert R Sciacca, Columbia Univ Sch of Nursing, New York, NY; Teresa Riga, Columbia Univ Irving Medical Ctr, New York, NY; Suzanne Bakken, Columbia Univ Sch of Nursing, New York, NY; Maurita Baumeister, Columbia Univ Irving Medical Ctr, New York, NY; Angelo B Biviano, Columbia Univ Medical Ctr, New York, NY; Jose M. Dizon, Columbia Univ Irving Medical Ctr, New York, NY; Daniel Wang, White Plains Hosp, White Plains, NY; Ketty C Wang, Columbia Univ Medical Ctr, New York, NY; William Whang, Icahn Sch of Med, New York, NY; Kathleen T Hickey, Columbia Univ, Trumbull, CT; Hasan Garan, New York Presbyterian Medical Ctr, New York, NY

2:45 PM

Q & A

2:50 PM

Measuring Medication Adherence in Acute Coronary Syndrome Patients Using Electronic Monitoring versus a Smartphone Application

**Nicholas A Giordano** , Kathryn A Riman, Rachel French, Marguerite Daus, Alisa Stephens, Stephen Kimmel, Barbara Riegel, Univ of Pennsylvania, Philadelphia, PA

2:55 PM

Q & A

# Moderated Digital Posters

## EP.MDP48 - The Air Around The Heart: Epidemiology of Pulmonary Diseases with Cardiovascular Implications

#### Moderated Posters 8, Science and Technology Hall

### Sunday, November 17, 2019, 2:10 PM - 3:00 PM

2:10 PM

Gender Differences in Circulating Biomarkers After Lung Transplantation

Lourdes Chacon, Texas Heart Inst, Houston, TX; Gabriel Loor, Daoud Daoud, Baylor Coll of Med, Houston, TX; Helen Andersson, Hassan Virk, Texas Heart Inst, Houston, TX; Natalie Debolske, Hyewon Choi, Peter Jindra, Matthew Cusick, Baylor Coll of Med, Houston, TX; Luiz Sampaio, **Doris A Taylor** , Texas Heart Inst, Houston, TX

2:15 PM

Q & A

2:20 PM

The Association of Inflammatory Response After Out of Hospital Cardiac Arrest With Lung Injury and the Impact of Respiratory Failure on Mortality

**Katarzyna Czerwinska-Jelonkiewicz** , American Heart of Poland Inc., Katowice, Poland; Johannes Grand, Rigshospitalet - Copenhagen Univ Hosp, Copenhagen, Denmark; Guido Tavazzi, Univ of Pavia, Pavia, Italy; Jordi Sans Rosello, Hosp de la Santa Creu i Sant Pau, Barcelona, Spain; Alice Wood, Glenfield Hosp,, Leicester, United Kingdom; Anna Oleksiak, Inst of Cardiology, Warsaw, Poland; Piotr Buszman, Mateusz Krysiński, American Heart of Poland Inc., Katowice, Poland; Alessandro Sionis, Hosp de la Santa Creu i Sant Pau, Barcelona, Spain; Christian Hassager, Rigshospitalet - Copenhagen Univ Hosp, Copenhagen, Denmark; Janina Stępinska, Inst of Cardiology, Warsaw, Poland

2:25 PM

Q & A

2:30 PM

Symptoms of Daytime Sleepiness Predict Inflammation and Ambulatory Blood Pressure in Sleep Apnea

Victoria Pak, **Brittany Butts** , Vicki Hertzberg, Nancy Collop, Arshed A Quyyumi, Ann Rogers, Sandra B Dunbar, Emory Univ, Atlanta, GA

2:35 PM

Q & A

2:40 PM

Improved Risk Stratification of Pulmonary Embolism With Combining the Simplified Pulmonary Embolism Severity Index With Echocardiography-Derived Tricuspid Annular Planar Systolic Excursion

Mehrdad Ghahramani, lisa domaradzki, Penn State Health, Hershey, PA; **Mohammed Ruzieh** , Penn State Heart and Vascular Insti, Hershey, PA; Ryan Wilson, Penn State Health, Hershey, PA; Brandon Peterson, Penn State Hershey Medical Ctr, Hershey, PA

2:45 PM

Q & A

2:50 PM

Persistent Asthma is Associated With Increased Risk for Incident Atrial Fibrillation in The Multi-Ethnic Study of Atherosclerosis (MESA)

**Matthew C Tattersall** , Univ of Wisconsin Hosp, Madison, WI; Alison S Dasiewicz, Robyn McClelland, Univ of Washington, Seattle, WA; Adam D Gepner, Univ of Wisconsin Hosp, Madison, WI; Matthew Kalscheur, Univ of Wisconsin, Madison, WI; Michael E Field, MUSC, Charleston, SC; Susan R Heckbert, Univ of Washington, Seattle, WA; Mohamed H Hamdan, Univ Wisconsin Sch of Med, Madison, WI; James H Stein, Univ of Wisconsin Med Sch, Madison, WI

2:55 PM

Q & A

# Moderated Digital Posters

## AT.MDP45 - Understanding Atherosclerotic Mechanisms: From Lipid Metabolism to the Endothelium

#### Moderated Posters 7, Science and Technology Hall

### Sunday, November 17, 2019, 2:10 PM - 3:00 PM

2:10 PM

Endothelial Dysfunction Protective Effects of Sulfated Non-Anticoagulant Low Molecular Weight Heparin in the Management of Sickle Cell Disease and Its Complications

**Shaker A Mousa** , Albany Coll of Pharmacy and Health Sciences, Rensselaer, NY; Kavitha Godugu, Noureldien H Darwish, Albany Coll of Pharmacy and Health Sciences, Renssealaer, NY; Shaymaa A Mousa, Albany Coll of Pharmacy and Health Sciences, Rensselaer, NY

2:15 PM

Q & A

2:20 PM

Marked Impairment of Endothelium-dependent Digital Vasodilatations in Patients With Microvascular Angina -possible Manifestation of Systemic Small Artery Disease

**Shoko Kajitani** , Takashi Shiroto, Shigeo Godo, Akiyo Ito, Yosuke Ikumi, Koichi Sato, Jun Sugisawa, Satoshi Tsuchiya, Akira Suda, Tomohiko Shindo, Shohei Ikeda, Kiyotaka Hao, Yoku Kikuchi, Kotaro Nochioka, Yasuharu Matsumoto, Jun Takahashi, Hiroaki Shimokawa, Tohoku Univ Graduate Sch of Med, Sendai, Japan

2:25 PM

Q & A

2:30 PM

Impairment of Endothelial Function by Aerosol From Marijuana Leaf Vaporizers

Jiangtao Liu, UCSF, San Francisco, CA; **Pooneh Nabavizadeh** , Univ of California, San Francisco, San Francisco, CA; Poonam Rao, UCSF, San Francisco, CA; Ronak Derakhshandeh, Univ of California, San Francisco, San Francisco, CA; Matthew L Springer, UCSF, San Francisco, CA

2:35 PM

Q & A

2:40 PM

**Outcomes and Determinants of Discrepant Coronary and Carotid Atherosclerosis**

**Hyoeun Kim** , Severance Hosp, Seoul, Korea, Republic of; Jong-Youn Kim, Pil-Ki Min, Young Won Yoon, Byoung Kwon Lee, Bum-Kee Hong, Se-Joong Rim, Hyuck Moon Kwon, Eui-young Choi, Gangnam Severance Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of

2:45 PM

Q & A

2:50 PM

Inositol Hexa Nicotinate is a Safe and Effective Alternative of Niacin for Treatment of Dyslipidemia

Danish H. Kazmi, Afroz Abidi, Era Medical Coll and Hosp, Lucknow, India; **Abdullah Zoheb Azhar** , Metropolitan Hosp Ctr, New York, NY; Ankit Sahu, Aditya Kapoor, Sanjay Gandhi Postgraduate Inst of Medical Science, Lucknow, India

2:55 PM

Q & A

# Moderated Digital Posters

## EA.MDP27 - Ventricular Arrhythmias/ SCD- Device and Patient Concerns

#### Moderated Posters 1, Science and Technology Hall

### Sunday, November 17, 2019, 2:10 PM - 3:00 PM

2:10 PM

Examining the Issues of Pacemaker/ICD Lead Parameters as a Function of an MRI Exam; Impact of the Peri-MRI Effect

**Adam Wetzel** , Loretta Gevenosky, Mark Doyle, Garima Dahiya, Andreas Kyvernitakis, Ronald Williams, Richard Lombardi, Moneal Shah, Robert W Biederman, Allegheny General Hosp, Pittsburgh, PA

2:15 PM

Q & A

2:25 PM

Q & A

2:30 PM

Sex-Differences in Arrhythmic Burden During the Use of the Wearable Cardioverter Defibrillator - Results From the WEARIT-II Registry

**Ido Goldenberg** , Univ of Rochester Medical Ctr, Rochester, NY; Julia Erath, J.W. Goethe Univ, Frankfurt am Main, Germany, Frankfurt, Germany; Andrea M Russo, Cooper Univ Hosp, Moorestown, NJ; Ashley Burch, Dept of Cardiovascular Sciences, East Carolina Univ, Greenville, North Carolina, USA, Rochester, NY; Birgit Assmus, Medical Univ of Vienna, Vienna, Austria, Vienna, Austria; Scott McNitt, Univ of Rochester Medical Ctr, Rochester, NY; Ilan Goldenberg, Valentina Kutyifa, Univ of Rochester, Rochester, NY

2:35 PM

Q & A

2:40 PM

Clinical Course in Carriers of the Ryanodine Receptor Type 2 P2328S Mutation Underlying Catecholaminergic Polymorphic Ventricular Tachycardia

**Mikael Koponen** , Annukka Marjamaa, Kimmo Kontula, Univ Central Hosp and Univ of Helsinki, Helsinki, Finland; Heikki Swan, Univ of Helsinki, Helsinki, Finland

2:45 PM

Q & A

2:50 PM

A Competing Risk Analysis of Ventricular Arrhythmia Events in Heart Failure Patients With Moderately-Severely Compromised Renal Function

**Ido Goldenberg** , Scott McNitt, Wojciech Zareba, Univ of Rochester Medical Ctr, Rochester, NY; Ilan Goldenberg, Valentina Kutyifa, Univ of Rochester, Rochester, NY

2:55 PM

Q & A

# Abstract Poster Session

## HF.APS.29 - A Heart Failure/Cardiomyopathy Potpourri

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2357

Real-world Characteristics of Patients With Heart Failure in China: Baseline Results From The Retrospective Non-interventional Nationwide Study (REPRESENT-HF)

**Jingmin Zhou** , Zhongshan Hosp, Fudan Univ, Shanghai, China; Xinli Li, First Afflitated Hosp, Nanjing Medical Univ, Nanjing, China; Yugang Dong, First Afflitated Hosp, Sun Yat-Sen Univ, Guangzhou, China; Jiefu Yang, Beijing Hosp, Beijing, China; Yong Huo, Peking Univ First Hosp, Beijing, China; Junbo Ge, Zhongshan Hosp, Fudan Univ, Shanghai, China

3:00 PM

Board # 2358

The Cardiotoxic Effect of Modern Anthracycline Dosing on Left Ventricular Ejection Fraction: A Systematic Review and Meta-Analysis of Randomised Controlled Trials

**Prajith Jeyaprakash** , Sukhman Sangha, Shanthosh Sivapathan, Katherine Ellenberger, Faraz Pathan, Kazuaki Negishi, Nepean Hosp, Kingswood, Australia

3:00 PM

Board # 2359

Patient Perceptions and Familiarity With Medical Therapy for Heart Failure

**Marc D Samsky** , Li Lin, Duke Univ, Durham, NC; Stephen J Greene, Duke Univ Medical Ctr, Durham, NC; Steven Lippmann, Duke Univ, Durham, NC; Pamela Peterson, Denver Health Medical Ctr, Denver, CO; Paul A Heidenreich, Palo Alto VA HCS, Palo Alto, CA; Warren K Laskey, Univ of New Mexico, Albuquerque, NM; Clyde W Yancy Jr., Northwestern Univ, Chicago, IL; Melissa Greiner, Chantelle Hardy, Duke Clinical Res Inst, Durham, NC; Abhishek Kavati, Natalie Park, Novartis Pharmaceuticals, East Hanover, NJ; Robert John Mentz, Duke Clinical Res Inst, Hillsborough, NC; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; Emily C Obrien, Duke Clinical Res Inst, Durham, NC

3:00 PM

Board # 2360

Work Smarter, Not Harder: Using Technology to Go From Worst to Best

**Diana C Otero Mostacero** , Persio David Lopez Loyo, Mount Sinai Hosp, New York, NY; Tanveer Hussain, James J Peters VAMC, Bronx, NY; Eder Cativo Calderon, James J Peters Bronx VA, New York, NY; Noor Fattouh, James J Peters VAMC, New York, NY; Robert Patrick, Louis Stokes Cleveland VAMC, Cleveland, OH; Ignat Glushko, Mahjabeen Rashid, James J Peters VAMC, Bronx, NY

3:00 PM

Board # 2361

Recurrent Heart Failure Hospitalizations Increase Risk of Cardiovascular and All-Cause Mortality in Heart Failure Patients With Comorbid Atrial Fibrillation, Type 2 Diabetes Mellitus, or Renal Impairment: An Analysis From Pygargus Database in Sweden

Krister Lindmark, Umeå Univ, Umea, Sweden; Kurt Boman, Skelefteå lasarett, Skelefteå, Sweden; Jan Stalhammar, Uppsala university, Uppsala, Sweden; Mona Olofsson, Skellefteå County Hosp, Skellefteå, Sweden; Raquel Lahoz, Rachel Studer, Novartis Pharma AG, Basel, Switzerland; Aaron Levine, Eleni Kopsida, Anna Castelo-Branco, IQVIA Solutions, Solna, Sweden; Clare Proudfoot, Novartis Pharma AG, Basel, Switzerland; **Stefano Corda** , Novartis, Basel, Switzerland; Anna Lundberg, Novartis Sverige AB, 16428 kista, Sweden; Ana Filipa Fonseca, Novartis Pharma AG, Basel, Switzerland; Charlotte Pettersson, IQVIA Solutions, Solna, Sweden; Gerhard Wikstrom, Akademisha, Uppskla, Sweden

3:00 PM

Board # 2362

Lipophilic, but Not Hydrophilic, Beta-blockers and Angiotensin Receptor Blockers Are Effective Treatments for Type 2 Pulmonary Hypertension

**Mathew J Platt** , Jason S Huber, Andrew J Foster, Jade P Marrow, Univ of Guelph, Guelph, ON, Canada; Renee Kinden, New Brunswick Heart Ctr, Saint John, NB, Canada; Shara Birnbaum, Jonathan D Mofford, Connor J Bochek, Univ of Guelph, Guelph, ON, Canada; James W.E Rush, Univ of Waterloo, Waterloo, ON, Canada; Sohrab Lutchmedial, New Brunswick Heart Ctr, Saint John, NB, Canada; Keith R Brunt, Dalhousie Med New Brunswick, Saint John, NB, Canada; Jeremy A Simpson, Univ of Guelph, Guelph, ON, Canada

3:00 PM

Board # 2363

Depression is Associated With an Increased Risk of Rehospitalization in Patients With Heart Failure: A Systematic Review and Meta-analysis

Jakrin Kewcharoen, Chol Techorueangwiwat, Univ of Hawaii, Honolulu, HI; Nattapat Nitinai, Chulalongkorn Univ, Bangkok, Thailand; Sakditad Saowapa, Ramatibadi Hosp, Bangkok, Thailand; Wasawat Vutthikraivit, Texas Tech Univ, Lubbock, TX; **Chanavuth Kanitsoraphan** , Pattara Rattanawong, Univ of Hawaii, Honolulu, HI

3:00 PM

Board # 2364

Prognostic Value of a New Systemic Nutrition-inflammation Index in Acute Decompensated Heart Failure Patients With Reduced, Mid-range and Preserved Left Ventricular Ejection Fraction

**Takahisa Yamada** , Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masahiro Seo, Osaka General Medical Ctr, Osaka City, Japan; Jun Nakamura, Makoto Abe, Kyoko Yamamoto, Kiyomi Kayama, Osaka General Medical Ctr, Osaka, Japan; Masatsugu Kawahira, Osaka General Medical Ctr, Oosaka, Japan; Kazuya Tanabe, Osaka General Medical Ctr, Osaka, NY; Yuto Tamura, Takeshi Fujita, Masatake Fukunami, Osaka General Medical Ctr, Osaka, Japan

3:00 PM

Board # 2365

Heart Failure Prescription Drug Spending and Medical Costs in Medicare Part D

**Blake T McGee** , Rishika Parikh, Georgia State Univ, Atlanta, GA; Victoria Phillips, Emory Univ, Atlanta, GA

3:00 PM

Board # 2366

Change in Qrs Duration Asa Predictor for Response to Sacubitril/valsartan in Heart Failure With Reduced Ejection Fraction

**Bong Joon Kim** , Han Su Park, Kosin Univ Gospel Hosp, Busan, Korea, Republic of

3:00 PM

Poster Professor

Michael M Givertz, Boston, MA

# Abstract Poster Session

## HF.APS.25 - Advances in Advanced Therapies

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2318

Heart Transplantation Outcomes in Cardiac Sarcoidosis

**Kamari C Jackson** , Quentin R Youmans, Amy Zhou, Allen S Anderson, Alexandru B Chicos, Ashley Ezema, Edwin Mandieka, Ramael Ohiomoba, Duc Pham, Susan R Russell, Peter H s Sporn, Clyde W Yancy Jr., Ike S Okwuosa, Northwestern Univ, Chicago, IL

3:00 PM

Board # 2319

Gender-Based Trends in Cardiac Transplant Complications and Related Outcomes in Heart Failure Patients in the United States - A 10 Year Analysis From a National Inpatient Database

**Abhishek Chaturvedi** , Craig Alpert, Matthew Lander, Manreet Kanwar, Allegheny General Hosp, Pittsburgh, PA; Raymond Benza, Allegheny Health Network, Pittsburgh, PA; Amresh Raina, Allegheny General Hosp, Pittsburgh, PA

3:00 PM

Board # 2320

Beta Blocker and Renin-angiotensin System Inhibitors Are Associated With Decreased Mortality in Patients With Left Ventricular Assist Devices

**Zeina Jedeon** , Rebecca Cogswell, Jessica Schultz, Ranjit John, Henri Roukoz, Univ of Minnesota, Minneapolis, MN

3:00 PM

Board # 2322

Efficacy and Safety of Four-Factor Prothrombin Complex Concentrate in the Patients With Mechanical Circulatory Support for Life-Threatening Bleeding or Emergent Surgery

**Keitaro Domae** , Osaka Police Hosp, Osaka, Japan; Yukitoshi Shirakawa, Osaka Police Hospial, Osaka, Japan; Ryo Kawasumi, Fumio Yamana, Kana Shibata, Osaka Police Hosp, Osaka, Japan; Koichi Toda, Shigeru Miyagawa, Daisuke Yoshioka, Osaka Univ, Osaka, Japan; Toshiki Takahashi, Osaka Police Hosp, Osaka, Japan; Yoshiki Sawa, Osaka Univ, Osaka, Japan

3:00 PM

Board # 2323

Achievement of Donor Management Goals Appears Protective Against Primary Graft Dysfunction After Heart Transplant

**Lillian Benck** , Evan Kransdorf, Jignesh Patel, Gabriela Rodriguez, SMIDT Heart Inst Cedars-Sinai, Los Angeles, CA; Darren Malinoski, Oregon Health & Science Univ, Portland, OR; Ryan Levine, SMIDT Heart Inst Cedars-Sinai, Los Angeles, CA; Claus Niemann, Univ of California San Francisco, San Francisco, CA; Jon A Kobashigawa, SMIDT Heart Inst Cedars-Sinai, Los Angeles, CA

3:00 PM

Board # 2324

Early Aspirin Use, Rejection, and the Development of Cardiac Allograft Vasculopathy Following Orthotopic Heart Transplantation

**Brian A Bergmark** , TIMI Study Group, Brigham and Women's Hosp and Harvard Medical Sch, Boston, MA; Thomas Alexander Zelniker, Brigham and Women's Hosp, Boston, MA; Miae Kim, Ctr for Advanced Heart Disease, Brigham and Women's Hosp, Boston, MA; Mandeep R Mehra, BRIGHAM AND WOMENS HOSPITAL, Boston, MA; Garrick C Stewart, BRIGHAM and WOMANS HOSPITAL, Boston, MA; Deborah Page, Erica Woodcome, Michael Givertz, Ctr for Advanced Heart Disease, Brigham and Women's Hosp, Boston, MA

3:00 PM

Board # 2325

Black Race and Male Gender Are Protective for Stroke Risk After LVAD: Time for Novel Mechanisms in the Era of Personalized Therapeutics

**Sriram Rao** , Univ of Pennsylvania, Philadelphia, PA; Vien Truong, Tan Tao Sch of Med, Long An; Eugene Chung, The Christ Hosp, Cincinatti, OH; Wojciech Mazur, The Christ Hosp, Cincinnati, OH; Daniel J Goldstein, Montefiore Medical Ctr, Bronx, NY; Ulrich P Jorde, Montefiore / Einstein, Bronx, NY; Jeff Teuteberg, Univ Pittsburgh, Pittsburgh, PA; Steven R Messe, Univ of Pennsylvania, Philadelphia, PA; Christopher S Hayward, St Vincent's Hosp, Darlinghurst, Australia; Thao P Ho-Le, Swinburne Univ of Technology, Hawthorn, Australia; Gregory Egnaczyk, Satya S Shreenivas, The Christ Hosp, Cincinnati, OH; J Eduardo Rame, Univ of Pennsylvania, Philadelphia, PA

3:00 PM

Board # 2326

Predicting Long-term Survival After Heart Transplant Using Post-transplant Cardiopulmonary Stress Tests

**Thomas C Hanff** , Robert S Zhang, Univ of Pennsylvania, Philadelphia, PA; Yuhui Zhang, Fuwai Hosp, Beijing, China; Maria Molina, Rhondalyn C McLean, Jeremy A Mazurek, Monique Tanna, J Eduardo Rame, Univ of Pennsylvania, Philadelphia, PA; Joyce W Wald, Univ of Pennsylvannia, Philadelphia, PA; Pavan Atluri, Michael A Acker, Univ of Pennsylvania, Philadelphia, PA; Mariell Jessup, American Heart Association, Dallas, TX; Lee R Goldberg, Edo Y Birati, Univ of Pennsylvania, Philadelphia, PA

# Abstract Poster Session

## AT.APS.12 - Aging and Vascular Disease

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 1023

Role of Low-Density Lipoprotein in Early Vascular Aging Associated With Systemic Lupus Erythematosus

**Hua-Chen Chan** , Kaohsiung Medical Univ Hospit, Kaohsiung, Taiwan; Hsiu-Chuan Chan, Chan-Jung Liang, Kaohsiung Medical Univ, Kaohsiung, Taiwan; Hsiang-chun Lee, Kaohsiung Medical Univ H, Kaohsiung City, Taiwan; Hung Su, Natl Sun Yat-Sen Univ, Kaohsiung, Taiwan; An-sheng Lee, Mackay Medical Coll, New Taipei City; Jentaie Shiea, Natl Sun Yat-Sen Univ, Kaohsiung, Taiwan; Wen-Chan Tsai, Tsan-Teng Ou, Cheng-Chin Wu, Kaohsiung Medical Univ Hospit, Kaohsiung, Taiwan; Chih-Sheng Chu, Kaohsiung Medical Univ, Kaohsiung, Taiwan; Richard A. Dixon, Texas Heart Inst, Houston, TX; Liang-Yin Ke, Jeng-Hsien Yen, Kaohsiung Medical Univ, Kaohsiung, Taiwan; Chu-Huang Chen, Texas Heart Inst, Houston, TX

3:00 PM

Board # 1024

Complement Mediated Macrophage Activation Inhibits Angiogenesis in Aged Femoral Artery-Ligated Mice

Yu Ma, ChengChao Ruan, **PingJin Gao** , Shanghai Jiao Tong Univ Sch of Med, Shanghai, China

3:00 PM

Board # 1025

Effects of Lung Matrices From Healthy Subjects or Patients With Chronic Lung Disease on the Growth and Fate of Human IPSC-derived Vascular Cells and Lung Progenitors

**Miriel Ho** , Mirabelle S.H. Ho, Ottawa Hosp Res Inst, Ottawa, ON, Canada; Robert Pouliot, Daniel J Weiss, Univ of Vermont, Burlington, VT; Duncan J Stewart, Ottawa Hosp Res Inst, Ottawa, ON, Canada

3:00 PM

Board # 1026

The Age of Bone Marrow Cells Determines Coronary the Age of Bone Marrow Cells Determines Coronary Collateral Growth

**Emily Sullivan** , Parisa Shabani, Molly Enrick, Lindsay Shockling, Vahagn A Ohanyan, Christopher Kolz, Taylor Elder, Thomas Pucci, William M Chilian, Liya Yin, Northeast Ohio Medical Univ, Rootstown, OH

3:00 PM

Board # 1027

Progressively Increased Arterial Stiffness Down the Aortic Tree in Aging Female Monkeys

**Denis Babici** , Rutgers New Jersey Medical Sch, Newark, NJ; Ray K Kudej, UMDNJ - NJMS, Newark, NJ; Tara McNulty, Rutgers New Jersey Medical Sch, Newark, NJ; Jie Zhang, Rutgers Univ- New Jersey, Newark, NJ; Marko Oydanich, New Jersey Medical Sch, Newark, NJ; Dorothy E Vatner, Stephen F Vatner, Rutgers Univ, Newark, NJ

3:00 PM

Board # 1028

Deletion of G Protein-Couple Receptor 39 Protects Mitochondrial Function in Endothelial Cells

**Sai Pranathi Meda Venkata** , Hainan Li, Megan M O'Meara, Jie-mei Wang, Wayne State Univ, Detroit, MI

3:00 PM

Board # 1029

Post Prandial Blood Glucose and Triglyceride Metabolism Govern Hematopoietic Stem Cell Transcriptional Regulation, Premature Aging and Rejuvenation

Keita Horitani, **Masayoshi Iwasaki** , Hiroshi Kishimoto, Kensaku Wada, Ichiro Shiojima, Kansai Medical Univ, Hirakata, Japan

3:00 PM

Board # 1030

Micrornaome Profiling on Senescent Human Vascular Smooth Muscle Cells

Diem Ngoc Duong Nguyen, Univ of Nottingham, Semenyih Selangor, Malaysia; William M Chilian, Northeast Ohio Medical Univ, Rootstown, OH; **Yuh Fen Pung** , Univ of Nottingham, Semenyih Selangor, Malaysia

3:00 PM

Board # 1031

Age-related SIRT1 Regulates Mitochondrial SIRT3 in Ischemic Heart

**Jingwen Zhang** , Xuan Li, Di Ren, Ying Han, Univ of South Florida, Tampa, FL; Jian Xiong X Chen, Univ Mississippi Medical Ctr, Jackson, MS; Ji Li, Univ of South Florida, Tampa, FL

3:00 PM

Board # 1032

Enhanced Senescence Expression in the Aortic Valve of Experimental Metabolic Syndrome Porcine

**Jason Go** , Mayo Clinic Fndn, Rochester, MN; Federico Franchi, Mayo Clinic, Rochester, MN; Seorin Kim, David Morse, Lisa Nesbitt, Mayo Clinic Fndn, Rochester, MN; Lilach O Lerman, Amir Lerman, Mayo Clinic, Rochester, MN

# Abstract Poster Session

## EA.APS.17 - Arrhythmia Analysis

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2100

Spectral Analysis of the Left Bundle Branch Block Qrs Differentiates Patients With Cardiomyopathy From Those With Normal Cardiac Function

**Mark J Niebauer** , Cleveland Clinic Fndn, Cleveland, OH; Niraj Varma, Cleveland Clinic, Cleveland, OH; John W Rickard, Mina K Chung, Patrick Tchou, Cleveland Clinic Fndn, Cleveland, OH

3:00 PM

Board # 2101

Characteristics of Purkinje Fiber Triggered Ventricular Fibrillation Storm

**James Coromilas** , Rutgers Robert Wood Johnson, Ridgewood, NJ; Amardeep Saluja, Columbia Univ Medical Ctr, New York, NY; Theodore Maglione, John Kassotis, William J. Kostis, Rutgers Robert Wood Johnson Medical Sch, New Brunswick, NJ

3:00 PM

Board # 2102

Increased Age, Left Atrial Size, and Body Mass Index in Patients With Atrial Fibrillation Alters Intracardiac Electrogram Morphology

**Isaac L Goldenthal** , Columbia Univ Irving Medical Ctr, New York, NY; Angelo B Biviano, Columbia Univ Medical Ctr, New York, NY; Edward John Ciaccio, Columbia Univ, New York, NY; Elaine Y. Wan, Central Park Place, New York, NY; Amardeep Singh Saluja, Columbia Univ Medical Ctr, New York, NY; Hasan Garan, New York Presbyterian Medical Ctr, New York, NY

3:00 PM

Board # 2103

Indexed Left Atrial Volume Predicts the Presence of Low Voltage Areas. The ZAQ Score

**Gabriele D'Ambrosio** , Silvio Romano, Univ of L'Aquila, L'Aquila, Italy; Obaida Alothman, Markus Frommhold, Georgi Borisov, Zentralklinik Bad Berka, Bad Berka, Germany; Giuseppe Patti, Univ of L'Aquila, L'Aquila, Italy; Karam Issa, Zentralklinik Bad Berka, Bad Berka, Germany; Maria Penco, Univ of L'Aquila, L'Aquila, Italy; Johann Christoph Geller, Otto-von-Guericke Univ Magdeburg, Magdeburg, Germany; Santi Raffa, Zentralklinik Bad Berka, Bad Berka, Germany

3:00 PM

Board # 2105

Incidence and Impact of Atrial Fibrillation in Critically Ill Septic Patients

**Abdullah Sarkar** , Univ of Miami, Miami, FL; Morvarid Zandiyeh, Cleveland Clinic Florida, Weston, FL; Mikhael F El-Chami, Emory Univ, Atlanta, GA; Elie Donath, Univ of Miami, Miami, FL; Talal Alzahrani, George Washington Univ, Arlington, VA; Mohammed Al-Hijji, Mayo Clinic, Rochester, MN; Rishi Anand, Jim Moran Heart and Vascular Ctr in Holy Cross Hosp, Fort Lauderdale, FL; Mohamad Adnan Alkhouli, Mayo Clinic, Rochester, MN

3:00 PM

Board # 2106

Antimuscarinic M2 Acetylcholinoreceptor Autoantibodies in Paroxysmal Atrial Fibrillation

**Ekaterina Mironova** , Natl Medical Res Ctr in Cardiology, Moscow, Russian Federation; Lada Layovich, Natalia Mironova, Tatiana Sharf, Nikolay Mironov, Kirill Zykov, Sergey Golitsyn, Natl Medical Res Ctr in, Moscow, Russian Federation

3:00 PM

Board # 2108

Atrial Conduction Delay Following Premature Stimulation Implies High Risk for Developing Postoperative Atrial Fibrillation in Cardiac Surgery Patients

**Muhammad Shuja Khan** , The Univ of Utah, Salt Lake City, UT; Kennosuke Yamashita, Showa Univ Northern Yokohama, Yokohama, Japan; Vikas Sharma, The Univ of Utah, Salt Lake City, UT; Ravi Ranjan, Univ Utah Hosp, Salt Lake Cty, UT; Craig Selzman, Utah Univ, Salt Lake City, UT; Derek J Dosdall, Univ of Utah, Salt Lake City, UT

3:00 PM

Board # 2109

Patient-Specific Computational Modeling Identifies Cryptogenic Stroke Patients With the Fibrotic Substrate for Atrial Fibrillation Perpetuation

**Savannah F Bifulco** , Sakher Sarairah, Zeinab Birjandian, Univ of Washington, Seattle, WA; Caroline H Roney, Steven A Niederer, King's Coll London, London, United Kingdom; Christian Mahnkopf, Peter Kühnlein, Marcel Mitlacher, Klinikum Coburg, Coburg, Germany; David Tirschwell, Univ of Washington, Seattle, WA; Nazem W Akoum, Univ Washington, Seattle, WA; Patrick M Boyle, Univ of Washington, Seattle, WA

# Abstract Poster Session

## EA.APS.16 - Arrhythmia in Genetic and Hereditary Cardiac Conditions

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2090

Brugada Syndrome Unmasked by Fever: A Comprehensive Review of Literature

**Sohaib S Roomi** , Waqas Ullah, Hassan Abbas, Abington Hosp-Jefferson Health, Abington, PA; Mahnoor Shirazi, Fndn Univ Medical Coll, Rawalpindi, Pakistan; Asrar Ahmad, Abington Hosp-Jefferson Health, Abington, PA

3:00 PM

Board # 2091

Inconsistency Between Epinephrine Provocation Test and Genetic Test in Type 2 Long QT Syndrome

**Yukiko Nakano** , Yuko Onohara, Takehito Tokuyama, Naoya Hironobe, Yousaku Okubo, Syo Okamura, Syunsuke Miyauchi, Yoshihiro Ikeuchi, Takahisa Yamada, Hidenori Ochi, Kazuaki Chayama, Yasuki Kihara, Hiroshima Univ, Hiroshima, Japan

3:00 PM

Board # 2092

Clinical Features and Long-Term Prognosis of Patients With Phenotype-Positive but Genotype-Negative Long-QT Syndrome

**Keiko Shimamoto** , Takeshi Aiba, Natl Cardiovascular Ctr, Suita, Japan; Tsukasa Kamakura, Natl Cerebral and Cardiovascular Ctr, Kyoto, Japan; Mitsuru Wada, Kenichiro Yamagata, Koji Miyamoto, Kohei Ishibashi, Natl Cardiovascular Ctr, Suita, Japan; Yuko Inoue, Osaka, Japan; Koji Miyamoto, Satoshi Nagase, Natl Cardiovascular Ctr, Suita, Japan; Takashi Noda, NCVC, Suita, Japan; Atsushi Takahashi, Natl Cardiovascular Ctr, Suita, Japan; Yoshihiro Miyamoto, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Toshihiro Tanaka, Tokyo Medical and Dental Univ, Tokyo, Japan; Seiko Ohno, Shiga Univ of Medical Sc, Otsu Shiga, Japan; Naomasa Makita, Nagasaki Univ, Nagasaki, Japan; Satoshi Yasuda, Natl Cerebral and Cardiovascular Ctr, Osaka, Japan; Wataru Shimizu, Nippon Medical Sch, Tokyo, Japan; Kengo F Kusano, Natl Cerebral and Cardiovascular Ctr, Osaka, Japan; Japanese-Multicenter registry Study for The Inherited Arrhythmias

3:00 PM

Board # 2093

Modern Treatments Can Abolish Mortality in Pediatric Patients With Hypertrophic Cardiomyopathy

**Aadhavi Sridharan** , Barry J Maron, Christopher Madias, Hassan Rastegar, Martin S Maron, Ethan J Rowin, Tufts Medical Ctr, Boston, MA

3:00 PM

Board # 2094

Personalized Virtual-Heart Technology Measures Ventricular Arrhythmia Inducibility in Patients With Hypertrophic Cardiomyopathy

**Ryan P O'Hara** , Johns Hopkins Univ, Baltimore, MD; Edem Binka, Johns Hopkins Hosp, Baltimore, MD; Mark J Cartoski, Nemours/Alfred I. DuPont Hosp for Children, Wilmington, DE; Adityo Prakosa, Arjun Somayazulu, Johns Hopkins Univ, Baltimore, MD; Stefan L Zimmerman, Johns Hopkins Hosp, Baltimore, MD; Natalia A Trayanova, Johns Hopkins Univ, Baltimore, MD

3:00 PM

Board # 2095

Arrhythmogenic Presentation of Two Rare Cases of Adipositas Cordis

Lisa Von Wald, Prabhjot Nijjar, **Henri Roukoz** , Univ of Minnesota, Minneapolis, MN

3:00 PM

Board # 2096

Asymptomatic Ventricular Arrhythmias Common in Family Members of Dilated Cardiomyopathy Patients Without Morphologic Dilated Cardiomyopathy

**David Hsu** , Brianna M Tucker, Stanford Med, Stanford, CA; Masataka Kawana, Matthew T Wheeler, Stanford Univ, Stanford, CA

3:00 PM

Board # 2097

Sustained And Non Sustained Ventricular Tachycardia Are Important Predictors To Differentiate Arrhythmogenic Right Ventricular Cardiomyopathy With Fat And Fibrotic Invasion To Left Ventricular Myocardium Using Four-dimensional Cardiac Computed Tomography

**Nobusada Funabashi** , Yoshio Kobayashi, Chiba Univ, Chiba, Japan

3:00 PM

Board # 2098

Utility of Drug Challenge Testing in Brugada Syndrome: A Systematic Review and Meta-Analysis

**Pattara Rattanawong** , Mayo Clinic, Phoenix, AZ; Wasawat Vutthikraivit, Texas Tech Health Sciences Ctr, Lubbock, TX; Jakrin Kewcharoen, Chol Techorueangwiwat, Univ of Hawaii, Honolulu, HI; Prapaipan Putthapiban, Einstein Medical Ctr, Philadelphia, PA; Narut Prasitlumkum, Univ of Hawaii, Honolulu, HI; Chanavuth Kanitsoraphan, Univ of Hawaii, honolulu, HI; Eugene Ho-Joon Chung, Univ of Michigan, Ann Arbor, MI

3:00 PM

Board # 2099

Impact Of T-peak To T-end Interval And Qrs Duration On The Risk Of Ventricular Arrhythmia Or Sudden Cardiac Death In Brugada Syndrome Patients: A Systematic Review And Meta-analysis

**Barbara Mantilla** , Pablo Paz, Texas Tech Univ, Lubbock, TX; Wasawat Vutthikraivit, Texas Tech Health Sciences Ctr, Lubbock, TX; Mohamed Elmassry, Texas Tech Univ Health S C, Lubbock, TX; Saif El Nawaa, Texas Tech Univ HSC, Lubbock, TX; M Rubayat Rahman, Texas Tech Univ, Lubbock, TX; Pattara Rattanawong, Univ of Hawaii, Honolulu, HI; Prapaipan Putthapiban, Einstein Medical Ctr, Philadelphia, PA; Scott W Shurmur, Texas Tech Univ, Lubbock, TX

# Abstract Poster Session

## EA.APS.14 - Arrhythmia Risk Stratification

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2069

Coarse Decision Trees Have a High Sensitivity in Predicting Post-Operative Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Grafting: Insights From Machine Learning From the Society of Thoracic Surgeons Database at a Single Institution

**Wasiq Sheikh** , Anshul Parulkar, Rhode Island Hosp, Providence, RI; Malik Bilal Ahmed, Brown Univ, Providence, RI; Brian Osler, Brown Univ, Lifespan, Providence, RI; Sanchita Parulkar, Rhode Island Hosp, Providence, RI; Esseim Sharma, Brian Daniel McCauley, Brown Univ, Providence, RI; Lauren Rousseau, Cardiovascular Inst, Providence, RI; Antony F Chu, Brown Univ, Providence, RI

3:00 PM

Board # 2070

Beyond the QT: Electrocardiographic Characteristics Preceding Dofetilide and Sotalol Induced Torsades De Pointes

**Joseph A Gottwald** , Anwar A Chahal, Grace Lin, Mayo Clinic, Rochester, MN; Anthony Holmes, Brian Young, Joel Xue, General Electric, Wauwatosa, WI; Virend K Somers, Mayo Clinic, Rochester, MN; Peter Brady, Iowa Heart Ctr - Iowa City, Iowa City, IA

3:00 PM

Board # 2071

Real-World Use of Implantable Loop Recorder Following Cryptogenic Stroke: Who Actually Benefits From Long Term Monitoring and How Long Should They Remain Implanted?

**Emily Howe** , Daniel Pugliese, Margaret Zhou, Joshua Z Willey, Hasan Garan, Jose M Dizon, Elaine Y. Wan, Columbia Univ Medical Ctr - New York Presbyterian, New York, NY

3:00 PM

Board # 2072

Visit-to-visit Blood Pressure Variability Predicts Recurrence of Atrial Fibrillation in Patients With Hypertension

**Naoko Hijioka** , Fukushima Medical Univ, Fukushima, Japan; Masashi Kamioka, Fukushima Medical Univ, Fukushima-City, Japan; Amami Kazuaki, Shinya Yamada, Takashi Kaneshiro, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

3:00 PM

Board # 2073

Are Electrocardiographic Markers Of Left Atrial Abnormality Associated With Acute Ischemic Stroke?

**Stephen McHugh** , Evan Harmon, Patrick Stafford, Kayvon Ghoreshi, Genevieve R Lyons, Sula Mazimba, Kenneth C Bilchick, Nina J Solenski, Bradford B Worrall, Younghoon Kwon, Univ of Virginia Health System, Charlottesville, VA

3:00 PM

Board # 2074

Coronary Microvascular Dysfunction and Atrial Fibrillation

**Anthony de la Pena** , Univ of Chicago Hosp, Chicago, IL; Tess Allan, Univ of Chicago Pritzker Sch of Med, Chicago, IL; John Blair, Univ of Chicago Hosp, Chicago, IL; Kathryn Dryer, Univ of Chicago Pritzker Sch of Med, Chicago, IL; Sanjiv J Shah, Northwestern Univ Feinberg Sch of Med, Chicago, IL; Stephanie A Besser, Cevher Ozcan, Univ of Chicago Hosp, Chicago, IL

3:00 PM

Board # 2075

Temporal Changes of Noninvasive Electrocardiographic Risk Factors for Sudden Cardiac Death in Post-Myocardial Infarction Patients With Preserved Ejection Fraction: Insights From The Preserve EF Study

**Iosif Xenogiannis** , Minneapolis Heart Inst and Minneapolis Heart Inst Fndn, Minneapolis, MN; Konstantinos Gatzoulis, First Dept of Cardiology, Natl and Kapodistrian Univ of Athens, Hippokrateion Hosp, Athens, Greece; Panayota Flevari, Ignatios Ikonomidis, Eustathios Iliodromitis, Second Cardiology Dept, Natl and Kapodistrian Univ of Athens, Attikon Hosp, Chaidari, Greece; Konstantinos Trachanas, State Dept of Cardiology, Hippokrateion Hosp, Athens, Greece; Konstantinos Vlachos, Second State Cardiology Dept, Evangelismos Hosp, Athens, Greece; Petros Arsenos, Univ of Athens, Medical Sch, Athens, Greece; Dimitris Tsiachris, Hippocrateion Hosp, Athens, Greece; Dimitrios Tousoulis, Hippokrateion Hosp, Athens, Greece; Emmanouil Brilakis, Minneapolis Heart Inst, Minneapolis, MN; Dimitrios Alexopoulos, Second Cardiology Dept, Natl and Kapodistrian Univ of Athens, Attikon Hosp, Chaidari, Greece

3:00 PM

Board # 2076

Association of Life's Simple 7 With Nonsustained Ventricular Tachycardia: The Atherosclerosis Risk in Communities Study

**Darshan Krishnappa** , Wendy Wang, Faye L Norby, Michael J Zhang, Jonathan Kim, Univ of Minnesota, Minneapolis, MN; Niki C Oldenburg, Univ of MN Cardiovascular Div, Minneapolis, MN; Elsayed Z Soliman, Wake Forest Sch of Med, Winston Salem, NC; Henri Roukoz, Wayne O Adkisson, Univ of Minnesota, Minneapolis, MN; Alvaro Alonso, Emory Univ, Atlanta, GA; Pamela L Lutsey, Lin Yee Chen, Univ of Minnesota, Minneapolis, MN

3:00 PM

Board # 2077

Atrial Fibrillation And Sleep Apnea: A Central Problem

**Evan Harmon** , Patrick Stafford, McCall Walker, Paras Patel, Jacob Blackwell, Sula Mazimba, Nishaki M Mehta, Kenneth C Bilchick, Younghoon Kwon, Univ of Virginia Health System, Charlottesville, VA

# Abstract Poster Session

## EA.APS.18 - Atrial Fibrillation Ablation II

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2110

Machine Learning Derived Features of Left Atrium, Pulmonary Veins, and Myocardium on CT Scans is Associated With Risk of Recurrence of Atrial Fibrillation Post-Ablation

Marjan Firouznia, Case Western Reserve Univ, Cleveland, OH; Michael LaBarbera, **Albert K Feeny** , Cleveland Clinic Fndn, Cleveland, OH; Zelin Zhang, Nanjing Univ of Information Science and Technology, Nanjing, China; Natalie Kalfas, Meghan McHale, Catherine Cantlay, Walid I Saliba, Patrick Tchou, Mina K Chung, Cleveland Clinic, Cleveland, OH; Anant Madabhushi, Case Western Reserve Univ, Cleveland, OH

3:00 PM

Board # 2111

Catheter Ablation of Atrial Fibrillation Reduces Muscle Sympathetic Nerve Activity and Improves Renal Function

**Yusuke Mukai** , Toyama Prefectural Central Hosp, Toyama City, Japan; Hideki Tokuhisa, Hiroyuki Sugimoto, Kanazawa Univ Hosp, Kanazawa City, Japan; Takuto Hamaoka, Kanazawa Univ Hosp, Kanazawa, Japan; Yoshitaka Okabe, Kanazawa Univ Hosp, Kanazawa City, Japan; Hisayoshi Murai, Kanazawa Univ, Kanazawa, Japan; Masayuki Takamura, Kanazawa Univ Hosp, Kanazawa, Japan

3:00 PM

Board # 2112

Thirty-day Readmissions After Catheter Ablation for Atrial Fibrillation in Patients With Heart Failure: Insights From the National Readmissions Database

**Fabio V Lima** , Brown Univ, Providence, RI; Kevin Kennedy, Statistical Consultant to Brown Univ - Rhode Island Hosp Cardiovascular Inst, Providence, RI; Lauren Rousseau, Brown Univ / Rhode Island Hosp, Providence, RI; Antony F Chu, Brown Univ, Providence, RI

3:00 PM

Board # 2113

Optimal Inter-Lesion Distance in Ablation Index-Guided Pulmonary Vein Isolation for Atrial Fibrillation

**Shuhei Kobayashi** , Hidehira Fukaya, Kitasato Univ, Sagamihara City, Japan; Shinichi Niwano, Kitasato Univ, Sagamihara, Japan; Tetsuro Sato, Gen Matsuura, Yuki Arakawa, Kitasato Univ, Sagamihara City, Japan; Yuki Shirakawa, Kitasato Univ, Sagamihara, Japan; Ai Horiguchi, Kitasato university, Sagamihara, Japan; Naruya Ishizue, Kitasato Univ, Sagamihara, Japan; Ryo Nishinarita, Kitasato Univ, Sagamihara City, Japan; Jun Oikawa, Jun Kishihara, Kitasato Univ, Sagamihara, Japan; Junya Ako, Kitasato Univ, Sagamihara City, Japan

3:00 PM

Poster Professor

Omer Berenfeld, Ann Arbor, MI

3:00 PM

Board # 2114

Volume-Pressure Loop Assessment of Changes in Left Atrial Function by Radiofrequency Catheter or Cryoballoon Ablation of Paroxysmal Atrial Fibrillation

**Antonios Karanasos** , Hippokration Hosp, Athens, Greece; Konstantinos Toutouzas, Hippokration Hosp, First Depart, Athens; Kostas Tyrovolas, Eyaggelismos General Hosp, Athens, Greece; Dimitris Tsiachris, Athens Medical Ctr, Athens, Greece; Michael Efremidis, Eyaggelismos General Hosp, Athens, Greece; Athanasios Kordalis, Hippokration Hosp, Athens, Greece; Maria Karmpalioti, Washington Univeristy in St. Louis, st. louis, MO; Constantina Aggeli, Hippokration Hosp, Athens, Greece; Christodoulos Stefanadis, Athens Medical Ctr, Athens, Greece; Dimitrios Tousoulis, Ippokrateio Hosp, Athens, Greece

3:00 PM

Board # 2115

Significance of Early Post Ablation Recurrence of Atrial Fibrillation in the Current Era; A Comparative Analysis Between Second Generation Cryoballoon and Contact Force Catheter

**Aditi Vaishnav** , Evan Levine, Kabir Bhasin, Neil E Bernstein, Nicholas T Skipitaris, Stavros E Mountantonakis, Northwell Health- Lenox Hill Hosp, New York, NY

3:00 PM

Board # 2116

Efficacy and Safety of the Cryoballoon-based Atrial Fibrillation Ablation in Patients Aged ≥ 80 Years

**Takashi Kanda** , Kansai Rosai Hosp, Amagasaki Hyogo, Japan; Masaharu Masuda, Kansai Rosai Hosp, Amagasaki, Japan; Mitsutoshi Asai, Osaka Police Hosp, Osaka, Japan; Osamu Lida, Shin Okamoto, Kansai Rosai Hosp, Amagasaki, Japan; Takayuki Ishihara, Kansai Rosai Hosp, Amagasaki, Japan; Kiyonori Nanto, Takuya Tsujimura, Shota Okuno, Kansai Rosai Hosp, Amagasaki, Japan; Yasuhiro Matsuda, Kansai Rosai Hosp Cardiovascular Ctr, Amagasaki, Japan; Toshiaki Mano, Kansai Rosai Hosp, Suita, Japan

3:00 PM

Board # 2117

Long-term Outcome in Patients With Electrical Isolation of the Left Atrial Appendage Performed at the 1st Procedure vs Redo in Patients With Long-standing Persistent Atrial Fibrillation

**Sanghamitra Mohanty** , Chintan G Trivedi, Domenico Giovanni Della Rocca, Carola Gianni, Bryan MacDonald, John Burkhardt, Javier Sanchez, Texas Cardiac Arrhythmia Inst, Austin, TX; Patrick M Hranitzky, Texas Cardiac Arrhythmia Inst, Hillsborough, NC; Joe Gallinghouse, Ugur Canpolat, Amin Al-ahmad, Rodney Paul Horton, Mohammed Bassiouny, Texas Cardiac Arrhythmia Inst, Austin, TX; Luigi Di Biase, 400 Central Park West Apt 9G, New York, NY; Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

3:00 PM

Board # 2118

Elongation of the High Right Atrium to Coronary Sinus Conduction Time Predicts the Recurrence of Atrial Fibrillation After Radiofrequency Catheter Ablation

**Yusuke Kanemaru** , Kumamoto Univ Hosp, Kumamoto, Japan; Yuichiro Arima, Kumamoto Univ, Kumamoto, Japan; Yusei Kawahara, Kumamoto Univ Hosp, Kumamoto, Japan; Takuya Kiyama, Dept of Cardiovascular Med, Graduate Sch of Medical Sciences, Kumamoto, Japan; Miwa Ito, Hisanori Kanazawa, Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

3:00 PM

Board # 2119

Prognostic Value of Periatrial Adipose Tissue and Thyroid Stimulating Hormone in Paroxysmal Atrial Fibrillation With Catheter Ablation

**Masato Kawasaki** , Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Atsush Kikuchi, Tsutomu Kawai, Masahiro Seo, Makoto Abe, Jun Nakamura, Kyoko Yamamoto, Kiyomi Kayama, Kazuya Tanabe, Masatsugu Kawahira, Osaka General Medical Ctr, Osaka, Japan

3:00 PM

Board # 2120

Decrement Evoked Potential Mapping Can Unmask Substrate of Atrial Fibrillation

**John L Fitzgerald** , John Hunter Hosp, Newcastle, Australia; Oscar Salvador-Montañes, Hosp Univrio Quironsalud Madrid and Univ Europea de Madrid, Madrid, Spain; Nicholas Jackson, John Hunter Hosp, Newcastle, Australia; Andreu Porta-Sanchez, Hosp Univrio Quirónsalud Madrid and Univ Europea de Madrid, Pozuelo de Alarcón (Madrid), Spain; Shouvik Haldar, Royal Brompton & Harefield NHS Fndn Trust, London, United Kingdom; Josh Cotton, Royal Brompton Hosp, London, United Kingdom; Sigfus Gizurarson, Natl Univ Hosp of Iceland, Reykjavik, Iceland; Kumaraswamy Nanthakumar, Toronto General Hosp, Toronto, ON, Canada

3:00 PM

Board # 2121

Interatrial Conduction Changes Following Radiofrequency Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation (paf)

**Alex B Torrelli-Diljohn** , Donald Quimby, Merl Wagoner, Zachary A Metka, Adam Zoble, Fabio Leonelli, James A. Haley Veterans Hosp, Tampa, FL

# Abstract Poster Session

## EA.APS.15 - Atrial Fibrillation Ablation III

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2078

Reduced Atrial Fibrillation Recurrence With Posterior Wall Isolation of the Left Atrium in Paroxysmal and Early Persistent Atrial Fibrillation

**Pankaj Malhotra** , Xin J Zhang, Eric Nordsieck, UC Davis Medical Ctr, Sacramento, CA; Neil Beri, Univ of California, Davis, Sacramento, CA; Dali Fan, Nayareh Pezeshkian, UC Davis Medical Ctr, Sacramento, CA; Uma Srivatsa, UC Davis, Sacramento, CA

3:00 PM

Board # 2079

Staying Power: Longer Ablation Durations Can Achieve Greater Lesion Volumes but Have Less Impact on Lesion Depths

**Duy Nguyen** , Lijun Zheng, Univ Colorado, Aurora, CO; Meg Babakhanian, Paul J Wang, Stanford Univ, Stanford, CA

3:00 PM

Board # 2080

Dressler's Syndrome Following Catheter Ablation of Atrial Fibrillation: A Case Series

**Domenico Giovanni Della Rocca** , St. David's Medical Ctr, Austin, TX; Luigi Di Biase Sr., Albert Einstein Coll of Med, New York, NY; Sanghamitra Mohanty, St.Davids Medical Ctr, Austin, TX; Chintan G Trivedi, Texas Cardiac Arrhythmia Inst, Austin, TX; Nicola Tarantino, Jorge Romero, Albert Einstein Univ, New York, NY; Bryan MacDonald, TCAI, Austin, TX; Carola Gianni, Texas Cardiac Arrhythmia Inst, Austin, TX; Amin Al-Ahmad, Mohammed Bassiouny, St. David's Medical Ctr, Austin, TX; Veronica Natale, Johns Hopkins Bloomberg, Baltimore, MD; J David Burkhardt, G Joseph Gallinghouse, St. David's Medical Ctr, Austin, TX; Rodney Paul Horton, Javier Sanchez, TCAI, Austin, TX; Andrea Natale, St. David's Medical Ctr, Austin, TX

3:00 PM

Board # 2081

Association Between Balloon Temperature Profile and Outcome of Pulmonary Vein Isolation With 2nd-generation Cryoballoon

**Naoko Hijioka** , Takashi Kaneshiro, Yoshiyuki Matsumoto, Minoru Nodera, Shinya Yamada, Fukushima Medical Univ, Fukushima, Japan; Masashi Kamioka, Fukushima Medical Univ, Fukushima-city, Japan; Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

3:00 PM

Board # 2082

Prophylactic Anti-Arrhythmic Drug During Blanking Period Suppress Long-Term Recurrence of Atrial Fibrillation After Catheter Ablation

**Ai Horiguchi** , Jun Oikawa, Hidehira Fukaya, Jun Kishihara, Satoh Akira, Daiki Saito, Tetsuro Sato, Gen Matsuura, Yuki Arakawa, Shuhei Kobayashi, Yuki Shirakawa, Ryo Nishinarita, Hironori Nakamura, Naruya Ishizue, Shinichi Niwano, Junya Ako, Kitasato Univ Sch of Med, Sagamihara, Japan

3:00 PM

Board # 2083

Lesion Size and Adjacent Tissue Damage Assessment With High Power and Short Duration Atrial Ablation: Comparison to Usual Radiofrequency Ablation Power Setting

**Yoshinari Enomoto** , Keijiro Nakamura, Rina Ishii, Toho Univ Ohashi Medical Ctr, Tokyo, Japan; Mahito Noro, Toho Univ. Ohashi Hosp, Tokyo, Japan; Kaoru Sugi, Toho Univ Ohashi Hosp, Tokyo, Japan; Raisuke Iijima, Toho university, Ohashi hospital, Tokyo, Japan; Hidehiko Hara, Toho Univ Med Ctr., Tokyo, Japan; Masao Moroi, Masato Nakamura, Toho Univ Ohashi Medical Ctr, Tokyo, Japan

3:00 PM

Board # 2084

Distinct Clinical Course by Type of Reverse Remodeling After Atrial Fibrillation Ablation in Patients With Left Ventricular Systolic Dysfunction

**Masato Okada** , Koichi Inoue, Koji Tanaka, Ohnishi Toshinari, Yuko Hirao, Takafumi Oka, Nobuaki Tanaka, Issei Yoshimoto, Ryo Kitagaki, Atsunori Okamura, Yasushi Koyama, Katsuomi Iwakura, Fujii Kenshi, Sakurabashi Watanabe Hosp, Osaka, Japan

3:00 PM

Board # 2085

Architecture of Fibrosis and Atrial Arrhythmia Recurrence After Catheter Ablation

**Mobin Kheirkhahan** , Matin Goldooz, Univ of Utah,, Salt Lake City, UT; Alex A Baher, Univ of Utah, Salt Lake City, UT; Alan K Morris, Univ of Utah,, Salt Lake City, UT; Brent Wilson, Univ Utah Sch Med, Salt Lake City, UT; Nassir F Marrouche, Univ of Utah, Salt Lake Cty, UT; Mihail G Chelu, Univ of Utah,, Salt Lake City, UT

3:00 PM

Board # 2086

Anatomical Relationship Between the Right Coronary Artery and Cavo-tricuspid Isthmus: An Intracardiac Echocardiography Study

**Carola Gianni** , Gökoğlan Yalçın, Sanghamitra Mohanty, Chintan Trivedi, Amin Al-Ahmad, J David Burkhardt, G Joseph Gallinghouse, Rodney P Horton, Patrick M Hranitzky, Javier E Sanchez, Luigi Di Biase, Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

3:00 PM

Board # 2087

Focal Impulse Rotor Modulation Guided Ablation versus Isolated Repeat Pulmonary Vein Isolation of Non-Paroxysmal Atrial Fibrillation After Failed Pulmonary Vein Isolation: A Case Control Study

**Graham Peigh** , Jeremiah Wasserlauf, Rachel M Kaplan, Amar Trivedi, Ansel P Amaral, Alexandru B Chicos, Rishi Arora, Susan Kim, Albert Lin, Nishant Verma, Bradley P Knight, Rod S Passman, Northwestern Univ, Feinberg Sch of Med, Chicago, IL

3:00 PM

Board # 2088

In the Presence of Low Voltage Areas, Substrate Modification Using Contact Force Sensing Adds Efficacy in Patients With Persistent Atrial Fibrillation

**Gabriele D'Ambrosio** , Univ of L'Aquila, L'Aquila, Italy; Santi Raffa, Zentralklinik Bad Berka, Bad Berka, Germany; Silvio Romano, Univ of L'Aquila, L'Aquila, Italy; Markus Frommhold, Zentralklini Bad Berka, Bad Berka, Germany; Obaida Alothman, Georgi Borisov, Karam Issa, Zentralklinik Bad Berka, Bad Berka, Germany; Giuseppe Patti, Maria Penco, Univ of L'Aquila, L'Aquila, Italy; Johann Christoph Geller, Otto-von-Guericke Univ Magdeburg, Magdeburg, Germany

3:00 PM

Board # 2089

Can the LAAOS Score Predict Recurrence IiPatients Undergoing Persistent Atrial Fibrillation Ablation? A Pilot Study

**Jose Henao** , Sokol Kalaveshi, HCA West Florida/USF Consortium - Brandon Regional Hosp, Brandon, FL; Stephen Mester, Bay Area Cardiology & Vascular - HCA West Florida/USF Consortium - Brandon Regional Hosp, Brandon, FL; Christian Perzanowski, Bay Area Cardiology & Vascular - Tampa General Hosp, Tampa, FL

# Abstract Poster Session

## HF.APS.30 - Brain-Heart Axis

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2367

Excess Neurohormonal Activation-Induced Heart Failure Results in Significant but Non-Critical Cardiomyocyte Telomere Shortening, Which is Associated With Impaired Myocardial Fatty Acid Utilization and Downregulation of MiR-133a and Fatty Acid Translocase (CD36)

**Moritz Brandt** , Hendrik Dörschmann, Venkata Garlapati, Philip Wenzel, Univ Medical Ctr Mainz, Mainz, Germany

3:00 PM

Board # 2368

Aging is Associated With Impaired Cardiac Autonomic Nervous System and Brain-derived Neurothrophic Factor (bdnf) Production

**Andrea Elia** , Univ of Naples Federico II, Naples, Italy; Alessandro Cannavo, Federico II Univ, naples, Italy; Maria Nolano, Nicola Ferrara, Univ of Naples Federico II, Naples, Italy; Nazareno Paolocci, Johns Hopkins Medical Insts, Baltimore, MD; Giuseppe Rengo, Univ of Naples Federico II, Naples, Italy

3:00 PM

Board # 2369

Obese Mice Exposed to Psychosocial Stress Display Cardiac and Hippocampal Impairment Associated With Local Brain-Derived Neurotrophic Factor Depletion

**Jacopo Agrimi** , Johns Hopkins Sch of Med, Baltimore, MD; Cristina Spalletti, CNR, Pisa, Italy; Carlotta Baroni, Scuola Superiore Sant'Anna, Pisa, Italy; Gizem Keceli, Stephen P Chelko, Djahida Bedja, Jun Seungho, Johns Hopkins Sch of Med, Baltimore, MD; Antonio Paolo P Beltrami, Univ` di Udine, Udine, Italy; Nazareno Paolocci, Johns Hopkins Univ, Baltimore, MD; Matteo Caleo, CNR, Pisa, Italy; Vincenzo Lionetti, Scuola Superiore Sant'Anna, Pisa, Italy

3:00 PM

Board # 2370

Humoral Factors - Released by Remote Ischemic Conditioning in Pigs - Exert Their Cardioprotection in Isolated Rat Hearts by Activation of the Intrinsic Cardiac Nervous System

Helmut Raphael Lieder, Amelie Irmert, Andreas Skyschally, Gerd Heusch, **Petra Kleinbongard** , Univ Hosp Essen, Essen, Germany

3:00 PM

Board # 2371

A Case of Cardiac Myeloid Sarcoma as an Uncertain Etiology of Heart Failure With Preserved Ejection Fraction

**Yogamaya Mantha** , Andrew Assaf, Rakushumimarika Harada, Benjamin Jones, Jasmeet Gill, Rahul Gill, Brian Le, Texas Health Presbyterian Hosp, Dallas, TX; Michinari Hieda, UT Southwestern Medical Ctr, Dallas, TX; Mark Feldman, Texas Health Presbyterian Hosp, Dallas, TX

# Abstract Poster Session

## EP.APS.20 - Cardiovascular Disease Prevention in Individuals with HIV Infection

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 3123

Exploratory Analysis of Human Immunodeficiency Virus Infection Among Sudden Death Victims

**Justin L Vandermolen** , UNC Hosp, Chapel Hill, NC; Mojtaba Mirzaei, Univ of North Carolina at Chapel Hill, Chapel Hill, NC; Venkata Narla, UNC, Chapel Hill, NC; Ross J Simpson Jr., Univ NC Heart, Chapel Hill, NC

3:00 PM

Board # 3124

Increased Prevalence of Diastolic Dysfunction in an HIV Clinical Cohort in Miami, FL: A Retrospective Analysis

**Louis T Vincent** , Univ of Miami, Miami, FL; Fahim Pyarali, Jackson Memorial Hosp, Miami, FL; Jelani Grant, Alexander Toirac, Univ of Miami, Miami, FL; Roumen Iordanov, Jackson Memorial Hosp, Miami, FL; Gerardo Zablah, Kunal Kapoor, Univ of Miami, Miami, FL; Michael Kaplan, Fahad Al Halban, Jackson Memorial Hosp, Miami, FL; Michael Kolber, Barry E Hurwitz, Claudia Martinez, Univ of Miami, Miami, FL

3:00 PM

Board # 3125

Real-World Status of Cardiovascular Health in Chinese Adults With HIV

Yi Huang, Chongqing Medical Univ, Chongqing, China; Xiaoqing He, Yaokai Chen, Chongqing Public Health Medical Ctr, Chongqing, China; **Wei Huang** , Chongqing Medical Univ, Chongqing, China

3:00 PM

Board # 3126

Association of HIV and HCV Status With New Onset Diastolic or Systolic Dysfunction in Women: The Women's Interagency HIV Study (WIHS)

**Sanyog Shitole** , Univ of California San Francisco, San Francisco, CA; Jason M Lazar, HSCB Fndn Inc, Brooklyn, NY; David B Hanna, Ryung Kim, Kathryn Anastos, Albert Einstein Coll of Med, Bronx, NY; Mario J Garcia, Montefiore Med Ctr, Bronx, NY; Joao A Lima, Johns Hopkins Univ, Baltimore, MD; Robert Kaplan, Albert Einstein Coll of Med, Bronx, NY; Jorge R Kizer, San Francisco VA Health Care System, San Francisco, CA

3:00 PM

Board # 3127

Pronostic Value of Non-Invasive Ischemic Testing in People Living With Human Immunodeficiency Virus

**Franck Boccara** , Sylvie Lang, Saint Antoine Univ Hosp, Paris, France; Stephane Ederhy, Saint Antoine Univ Hosp, Paris CEDEX 12, France; Laurie Soulat-Dufour, Hôpital Saint Antoine, Paris, France; Saroumadi Adavane-Scheuble, Yann Ancedy, Marion Chauvet-Droit, Pascal Nhan, Jean Luc Meynard, Saint Antoine Univ Hosp, Paris CEDEX 12, France; Marc Antoine Valentin, Pitié Salpêtrière Univ Hosp, Paris, France; Laurence Slama, Hotel Dieu Univ Hosp, Paris, France; Gilles Pialoux, Tenon Univ Hosp, Paris, France; Christine Katlama, Pitié Salpêtrière Univ Hosp, Paris, France; Pierre Marie Girard, Saint Antoine Univ Hosp, Paris, France; Ariel Cohen, Saint Antoine Univ Hosp, Paris CEDEX 12, France

3:00 PM

Board # 3128

Prevalence and Impact of Cardiovascular Disease in Patients With HIV: A Nationwide Prospective

**Mohit Pahuja** , DMC-Wayne State Univ, Detroit, MI; Omar Chehab, Ahmed Yassin, Detroit Medical Ctr/Wayne State Univ, Detroit, MI; Venkat Ramesh, Apollo Hosp, Hyderabad, India; Hossam Abubakar, Wayne State Univ, Detroit, MI; Sagar Ranka, John H Stroger Hosp of Cook Cou, Chicago, IL; Aman Handa, Kasturba Medical Coll, Manipal, India; Tanvir Khosla, St George Univ, Grenada, Grenada; Luis Afonso, Harper Univ Hosp, Detroit, MI; Ileana L Pina, Detroit Medical Ctr Heart Hosp, Cleaveland Hghts, OH

3:00 PM

Board # 3129

Persons Living With Human Immunodeficiency Virus With Intermediate Cardiovascular Disease Risk: Are Statin Prescription Rates for These At-Risk Patients Changing?

**Keva Garg** , Duke Univ, Durham, NC; Robert John Mentz, Duke Clinical Res Inst, Hillsborough, NC; Gerald S Bloomfield, Duke Univ Medical Ctr, Durham, NC; Nwora Lance Okeke, 62 Lake Village Drive, Durham, NC

3:00 PM

Board # 3130

Inpatient Outcomes of Infective Endocarditis in Patients With HIV: Analysis From the National Inpatient Sample

**Mohamed Khayata** , Cleveland Clinic, Cleveland, OH; Nour Tashtish, Univ Hosp Cleveland Ctr, Cleveland, OH; Sadeer Al-Kindi, Univ Hosp Cleveland Medical Ctr, Cleveland, OH; Antoine Addoumieh, Univ of North Dakota, Grand Forks, ND; Saqer Alkharabsheh, Beni R Verma, Cleveland Clinic, Cleveland, OH; Muhammad Mohsin Furqan, Cleveland Clinic Fndn, Cleveland, OH; Nishant P Shah, Cleveland Clinic, Cleveland Heights, OH; Guilherme H Oliveira, Univ Hosp Cleveland Medical Ctr, Cleveland, OH; Allan L Klein, Cleveland Clinic, Cleveland, OH

3:00 PM

Board # 3131

Utilization of Absolute Monocyte Counts to Predict Cardiovascular Events in Persons Living With Human Immunodeficiency Virus

**Milana Bogorodskaya** , Beth Israel Deaconess Medical Ctr, Boston, MA; Asya Lyass, Taylor F Mahoney, Boston Univ, Boston, MA; Pritha Sen, Massachusetts General Hosp, Boston, MA; Chris Longenecker, Case Western Reserve Univ, Cleveland, OH; Joseph Massaro, Ralph B D'Agostino Sr., Boston Univ, Boston, MA; Virginia A Triant, Massachusetts General Hosp, Boston, MA

3:00 PM

Board # 3132

Atrial Fibrillation in Persons Living With HIV: A Single-Center Retrospective Analysis

**Jelani K Grant** , Fahim Pyarali, Louis Vincent, Roumen Iordanov, Alexander Toirac, Univ of Miami/Jackson Memorial Hosp, Miami, FL; Kunal Kapoor, Univ of Miami/Jackson Memoril Hosp, Miami, FL; Gerardo Zablah, Bertrand F Ebner, Michael Kaplan, Fahad Al Haban, Univ of Miami/Jackson Memorial Hosp, Miami, FL; Michael Kolber, Barry E Hurwitz, Claudia Martinez, Univ of Miami, Miami, FL

3:00 PM

Poster Professor

Matthew J. Feinstein, Chicago, IL

# Abstract Poster Session

## LF.APS.07 - Cardiovascular Risk Factors and Biomarkers

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 3187

Association of Metabolic Syndrome With Sudden Death

**Murrium I. Sadaf** , Mojtaba Mirzaei, Yale-Waterbury Internal Med Program, Waterbury, CT; Brittany Bogle, IBM Data Science and AI Elite Team, Raleigh-Durham, NC; Nisha Hosadurg, Tufts Medical Ctr, Boston, MA; Golsa Joodi, Yale Sch of Med, New Haven, CT; Ross J Simpson, Univ NC Heart, Chapel Hill, NC

3:00 PM

Board # 3188

Effects of Chronic Electronic Cigarette Vapor Exposure on Cardiac Function in a Rat Experimental Myocardial Infarction-reperfusion Model

**Wangde Dai** , Jianru Shi, Juan Carreno, Huntington Medical Res Institu, Pasadena, CA; Michael T Kleinman, David A. Herman, Rebecca M. Johnson, Samantha Renush, Irene Hasen, Air Pollution Health Effects Lab, Irvine, CA; Robert A. Kloner, Huntington Medical Res Institu, Pasadena, CA

3:00 PM

Board # 3189

Preoperative Disturbances of Glucose Metabolism and Mortality After Coronary Artery Bypass Grafting

**Catarina Djupsjo** , Karolinska Instt,, Stockholm, Sweden; Ulrik Sartipy, Karolinska Univ Hosp, Stockholm, Sweden; Torbjorn Ivert, Karolinska Instt,, Stockholm, Sweden; Stelios Karayiannides, Karolinska Instt, Danderyd´s Hosp, Stockholm, Sweden; Pia Lundman, Karolinska Instt Danderyds Sjukhus, Stockholm, Sweden; Thomas Nystrom, Karolinska Instt,, Stockholm, Sweden; Martin J Holzmann, Karolinska Instt, Stockholm, Sweden; Jeanette Kuhl, Karolinska Instt,, Stockholm, Sweden

3:00 PM

Board # 3190

Associations Between Urinary Isoprostane Levels and Cardiovascular Risk Factors in the Coronary Artery Risk Development in Young Adults (CARDIA) Study

**Amir S Heravi** , Dhananjay Vaidya, Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD; Di Zhao, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Bharath Ambale-Venkatesh, Henrique Doria De Vasconcellos, Johns Hopkins Sch of Med, Baltimore, MD; Donald M Lloyd-jones, Northwestern Univ, Chicago, IL; Pamela Schreiner, Univ of Minnesota, Minneapolis, MN; Jared P Reis, Natl Inst of Health, Bethesda, MD; Cora E Lewis, Univ of Alabama at Birmingham, Birmingham, AL; Stephen Sidney, Kaiser Permanente Medical Care, Oakland, CA; Colin Wu, Natl Insts of Health, Bethesda, MD; Chiadi E Ndumele, Johns Hopkins Sch of Med, Baltimore, MD; Eliseo Guallar, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Pamela Ouyang, Johns Hopkins Sch of Med, Baltimore, MD; Ron C Hoogeveen, Baylor Coll of Med, Houston, TX; Joao A Lima, Wendy S Post, Johns Hopkins Sch of Med, Baltimore, MD

3:00 PM

Board # 3191

Cardiovascular Risk Factors in American Adults Aged 18-44: From the National Health and Nutrition Examination Survey

**Rajat Kalra** , Univ of Minnesota, Minneapolis, MN; Nirav Patel, Anirudh Bhargava, Vibhu Parcha, Univ of Alabama at Birmingham, Birmingham, AL; Katherine S Booker, Abbott Northwestern and Children's Minnesota, Minneapolis, MN; Garima Arora, Pankaj Arora, Univ of Alabama at Birmingham, Birmingham, AL

3:00 PM

Board # 3192

Proteinuria Decreased the Estimated Glomerular Filtration Rate in Diabetic Patients: 12 Year Follow-Up Study

**Hirofumi Soejima** , Kumamoto Univ, Kumamoto City, Japan; Takeshi Morimoto, Hyogo Coll of Med, Nishinomiya City, Japan; Sadanori Okada, Nara Medical Univ, Kashihara City, Japan; Chisa Matsumoto, Tokyo Medical Univ, Shinjuku-Ku, Japan; Masafumi Nakayama, Nakayama Cardiovascular Clinic, Amakusa City, Japan; Hideaki Jinnouchi, Jinnouchi Clinic, Kumamoto City, Japan; Masako Waki, Shizuoka City Shizuoka Hosp, Shizuoka City, Japan; Izuru Masuda, Takeda Hosp, Kyoto City, Japan; Yoshihiko Saito, Nara Medical Univ, Kashihara, Japan; Hisao Ogawa, Natl Cerebral Cardiovascular Ctr, Suita Osaka, Japan

3:00 PM

Board # 3193

Does Severity of Sleep Apnea Affect Compliance With CPAP Therapy?

David Golombeck, **Jacqueline Pimienta** , Nicolle Sara Milstein, The Valley Hosp, Ridgewood, NJ; Advay G Bhatt, The Valley Health System, Paramus, NJ; Tina Claudia Sichrovsky, Valley Hosp, Ridgewood, NJ; Mark Preminger, Valley Hosp, Paramus, NJ; David Rosen, Jeannean Hernandez, Carissa Pistilli, The Valley Hosp, Ridgewood, NJ; Suneet Mittal, The Valley Hosp, New York, NY; Dan L Musat, Valley Health System, New York, NY

3:00 PM

Board # 3194

Not Day-By-Day Variability but Average Level in Morning Systolic Blood Pressure: A Strong Indicator of Left Ventricular Mass Index in The High-Risk Japanese of Cardiovascular Disease

**Michiaki Nagai** , Hiroshima City ASA Hosp, Hiroshima, Japan; Satoshi Hoshide, JICHI Medical Univ, Shimotsuke, Japan; Kazuomi Kario, JICHI Medical Univ, Tochigi-ken, Japan

3:00 PM

Board # 3195

Prevalence of E-Cigarette Use Among US Adolescents: Youth Behavioral Risk Factor Survey (YBRFS) 2017

**Hassan Mirbolouk** , Johns Hopkins Univ, Baltimore, MD; Sina Kianoush, Yale Univ, Waterbury, CT; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; SM Iftekhar Uddin, Omar Dzaye, Olusola Orimoloye, Johns Hopkins Univ, Baltimore, MD; Mahmoud S Al Rifai, Univ of Kansas, Wichita, KS; Zeina Dardari, Omar El-Shahaway, Johns Hopkins Univ, Baltimore, MD; Khurram Nasir, Baptist Health South Florida, New Haven, CT; Albert Danso Osei, Johns Hopkins Sch of Med, Baltimore, MD

3:00 PM

Board # 3196

Sun Protective Behavior is Associated With a Higher Chance of Having Hypertension but Varies by Race

**Zachary J Wanken** , J. Aaron Barnes, Philip P Goodney, Dartmouth-Hitchcock Medical Ctr, Lebanon, NH

3:00 PM

Board # 3197

Association of Ldl-c Level With Outcomes in Patients With Chronic Kidney Disease and no History of Atherosclerotic Cardiovascular Disease

**Roy O Mathew** , Columbia VA Health Care System, Blythewood, SC; Mandeep S Sidhu, Albany Stratton VA Med Ctr, Albany, NY; Janani Rangaswami, Einstein Medical Ctr, Philadelphia, PA; Sripal Bangalore, New York Univ Sch of Med, New York, NY

3:00 PM

Board # 3198

Determinants of Cardiovascular Health Among Middle-Age and Older Adults Ethnic Groups

**Kyungeh An** , Virginia Commonwealth Univ, Richmond, VA; Tae Shik Park, Virginia Commonwealth Univ HS, Richmond, VA; Cheongtag Kim, Seoul Natl Univ, Seoul

3:00 PM

Board # 3199

Risk Factors and Outcomes of Young Adults With First Myocardial Infarction: Insight From Gulf Coast Registry

**Abdulhamied Alfaddagh** , The Johns Hopkins Hosp, Baltimore, MD; Mohammad Zubaid, Kuwait Univ, Safat; Wafa Rashed, Ministry of Health, Kuwait, Kuwait

# Abstract Poster Session

## LF.APS.08 - Clinical Lipidology

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 3200

Gender Difference in the Prognostic Effect of High Density Lipoprotein Cholesterol in Patients With Atherosclerotic Cardiovascular Disease Under Statin Treatment

**Li Yi-heng** , Natl Cheng Kung Univ Hosp, Tainan, Taiwan; Wei-Kung Tseng, E-Da Hosp, Kaohsiung, Taiwan; Wei-Hsian Yin, Cheng-Hsin General Hosp, Taipei, Taiwan; Fang-Ju Lin, Natl Taiwan Univ, Taipei, Taiwan; Yen-Wen Wu, Far Eastern Memorial Hosp, New Taipei City, Taiwan; I-Chang Hsieh, Chang Gung Memorial Hosp, Taipei, Taiwan; Tsung-Hsien Lin, Kaohsiung Medical Univ Hosp, Kaohsiung, Taiwan; Wayne Huey-Herng Sheu, Taichung Veterans General Hosp, Taichung, Taiwan; Hung-I Yeh, Mackay Memorial Hosp, Taipei, Taiwan; Jaw-Wen Chen, Natl Yang Ming Univ, Taipei, Taiwan; Chau-Chung Wu, Natl Taiwan Univ Hosp, Taipei, Taiwan

3:00 PM

Board # 3201

Cholesterol Efflux Capacity & Collateral Circulation in Patients With Chronic Total Coronary Occlusion

**Seonhwa Lee** , Eun Jeong Cheon, Severance Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Chan Joo Lee, Jaewon Oh, Yonsei Univ, Seoul, Korea, Republic of; Sungha Park, Yonsei Univ Medical Coll, Seoul; SeokMin kang, Severance Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Sang-Hak Lee, Yonsei Univ Coll of Med, Seoul

3:00 PM

Board # 3202

Efficacy And Safety Of Bempedoic Acid In Statin Treated Or Intolerant Patients- Current Evidence From The Randomized Controlled Trials

**Senada Malik** , Univ of New England, Biddeford, ME

3:00 PM

Board # 3203

Is Palmar Striated Xanthomas Really Pathognomonic of Type III Dysbetalipoproteinemia?

**Nathalie Roy** , Univ de Montreal, Chicoutimi, QC, Canada; Etienne Khoury, Ecogene-21, Chicoutimi, QC, Canada; Daniel Gaudet, Diane Brisson, Univ de Montreal, Chicoutimi, QC, Canada

3:00 PM

Board # 3204

Fasting Compared With Nonfasting Triglycerides and Risk of Cardiovascular Events in Diabetic Patients Under Statin Therapy

**Hayato Tada** , Kanazawa Univ, Kanazawa, Japan; Akihiro Nomura, Kanazawa Univ Graduate Sch of Med, Kanazawa, Japan; Masayuki Takamura, Kanazawa Univ Hosp, Kanazawa, Japan; Masa-aki Kawashiri, Kanazawa Univ, Kanazawa, Japan

3:00 PM

Board # 3205

Improvement of Endothelial Dysfunction is Mediated Through Reduction of Remnant Lipoprotein After Statin Therapy in Patients With Coronary Artery Disease

**Takamitsu Nakamura** , Univ of Yamanashi, Chuo, Japan; Manabu Uematsu, Yamanashi Univ, Chuo, Japan; Toru Yoshizaki, Univ of Yamanashi, Chuo, Japan; Tsuyoshi Kobayashi, Dept of Internal medicine II, Yamanashi, Japan; Takeo Horikoshi, Univ of Yamanashi, chuo, Japan; Yosuke Watanabe, Kiyotaka Kugiyama, Univ of Yamanashi, Chuo, Japan

3:00 PM

Board # 3206

Contributions of Electronegative Low-Density Lipoprotein to Arterial Stiffness and Cognitive Decline in Patients With Alzheimer's Disease

Mei-Chuan Chou, Kaohsiung Municipal Ta-Tung Hosp, Kaohsiung Medical Univ, Kaohsiung, Taiwan; Shiou-Lan Chen, Liang-Yin Ke, Kaohsiung Medical Univ, Kaohsiung, Taiwan; Ming-Hsien Tasi, Univ of Science and Technology, Pingtung, Taiwan; Sharon Chia-Ju Chen, Kaohsiung Medical Univ, Kaohsiung, Taiwan; Chih-Sheng Chu, Kaohsiung Municipal Ta-Tung Hosp, Kaohsiung Medical Univ, Kaohsiung, Taiwan; Chiou-Lian Lai, Kaohsiung Medical Univ, Kaohsiung, Taiwan; Chu-Huang Chen, Texas Heart Inst, Houston, TX; **Ching-Kuan Liu** , Kaohsiung Medical Univ, Kaohsiung, Taiwan

3:00 PM

Board # 3207

Small Dense Low-density Lipoprotein Cholesterol as a Predictor for Rapid Progression of Non-culprit Lesion in Patients With Acute Coronary Syndrome

**Teruo Sekimoto** , Showa Univ Sch of Med, Tokyo, Japan; Shinji Koba, 1-5-8 HATANODAI, Tokyo, Japan; Toshiro Shinke, Ken Arai, Yousuke Oishi, Kunihiro Ogura, Hiroaki Tsujita, Seita Kondo, Hideaki Tanaka, Makoto Shoji, Showa Univ Sch of Med, Tokyo, Japan

3:00 PM

Board # 3208

Comparison Of A Novel Method Vs The Friedewald Equation For Low Density Lipoprotein Cholesterol Estimation In Patients With Hypertriglyceridemia

**Aparna Sajja** , The Johns Hopkins Hosp, Baltimore, MD; Vasanth Sathiyakumar, Johns Hopkins Hosp, Baltimore, MD; Jihwan Park, The Johns Hopkins Hosp, Baltimore, MD; Vincent Pallazola, Johns Hopkins Hosp, Baltimore, MD; Eliseo Guallar, JHH, Baltimore; Mariano Lazo, The Johns Hopkins Hosp, Baltimore, MD; Steven R Jones, The Johns Hopkins Univ, Baltimore, MD; Seth S Martin, Johns Hopkins Univ, Baltimore, MD

3:00 PM

Board # 3209

Relationship Between Baseline TRS2P Score and LDL-C Alone or in Combination in Predicting the Absolute Benefits of More Versus Less Intensive Statin Therapy in an ASCVD: Analysis From the TNT Trial

**Toshiyuki Nishikido** , Saga Univ, Saga, Japan; Rana Fayyad, Pfizer Inc., New York, NY; Shari A Melamed, Pfizer inc., Chappaqua, NY; Kausik K Ray, Imperial Coll London, London, United Kingdom

3:00 PM

Board # 3210

The Association of Serum Cholesterol and ASCVD and Non-ASCVD Hospitalization Rate Across CKD Stages in 2 Million US Veterans

Jui-Ting Hsiung, UC Irvine, Orange, CA; Melissa Soohoo, VA Long Beach, Long Beach, CA; Christina Park, UC Irvine, Orange, CA; Maria Marroquin, VA Long Beach, Long Beach, CA; Hamid Moradi, Long Beach VA Health Care System, Long Beach, CA; Csaba Kovesdy, Univ of Tennessee Health Science Ctr, Memphis, TN; Kamyar Kalantar-Zadeh, Univ of California Irvine, Orange, CA; **Elani Streja** , Univ of California, Irvine, Orange, CA

# Abstract Poster Session

## EP.APS.22 - Clinical Outcomes Studies

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 3143

Dabigatran-Associated Bleedings May Result From Pharmacokinetic Interactions With Mild P-gp Inhibitors in Very Elderly Patients

Marjorie Bernier, Nadege Parassol, Thibaud Lavrut, **Milou-Daniel Drici** , Univ of Nice Cote d'Azur Medical Ctr, Nice Cedex 1, France

3:00 PM

Board # 3144

Health and Economic Consequences of Major Gastrointestinal Bleeding Among Nonvalvular Atrial Fibrillation Patients Who Initiated Treatment With Oral Anticoagulants

Steve Deitelzweig, Ochsner Clinic Fndn, New Orleans, LA; Allison Keshishian, STATinMED Res and New York City Coll of Technology, Ann Arbor, MI; Amiee Kang, Amol Dhamane, Bristol-Myers Squibb Company, Lawrenceville, NJ; Xuemei Luo, Pfizer, Inc., Groton, CT; **Neeraja Balachander** , Lisa Rosenblatt, Bristol-Myers Squibb Company, Lawrenceville, NJ; Jack Mardekian, Pfizer, Inc., New York, NY; Jenny Jiang, Bristol-Myers Squibb Company, Lawrenceville, NJ; Huseyin Yuce, New York City Coll of Technology, New York, NY; Gregory Y.H. Lip, Liverpool Ctr for Cardiovascular Science, Univ of Liverpool and Liverpool Heart & Chest Hosp, Liverpool, United Kingdom

3:00 PM

Board # 3145

Outcomes After Switching Anticoagulation From Warfarin to DOACs in Patients With Non-valvular Atrial Fibrillation

**Shinichiro Ueda** , Univ of the Ryukyus, Nishihara-cho, Japan; Takeshi Morimoto, Hyogo Medical Colleage, Nishinomiya, Japan; DOAC3 Cohort study group

3:00 PM

Board # 3146

Oral Anticoagulation Therapy in Patients Hospitalized With Non-Valvular Atrial Fibrillation: A Nationwide Cohort Study

**Kuan Ken Lee** , Rong Bing, Federica Astengo, Univ of Edinburgh, Edinburgh, United Kingdom; Jesus Perez, Univ of Glasgow, Glasgow, United Kingdom; Atul Anand, Univ of Edinburgh, Edinburgh, United Kingdom; Nathan Hill, Bristol-Myers Squibb Pharmaceuticals Ltd, London, United Kingdom; Nicholas Bloor, Pfizer Pharmaeuticals Ltd, Surrey, United Kingdom; Steven Lister, Bristol-Myers Squibb UK Ltd., Uxbridge; David McAllister, Univ of Glasgow, Glasgow, United Kingdom; Nicholas L Mills, Univ Edinburgh, Edinburgh, United Kingdom; Anoop SV Shah, Univ of Edinburgh, Edinburgh, United Kingdom

3:00 PM

Board # 3147

Is Lipid Lowering Therapy Being Intensified in the United States?: Primary, One-year Results of the Getting to an Improved Understanding of Low-density Lipoprotein Cholesterol and Dyslipidemia Management (GOULD) Registry of Patients With Atherosclerotic Cardiovascular Disease (ASCVD)

**Christopher Paul Cannon** , Brigham and Women's Hosp, Boston, MA; James A De Lemos, UT Southwestern Medical Ctr, Dallas, TX; Christie M Ballantyne, Baylor Coll of Med, Houston, TX; Robert S Rosenson, Mt Sinai Sch of Med, New York, NY; Shushama Alam, Mary Elliott-Davey, Katie Mues, Amgen, Thousand Oaks, CA; Yuyin Liu, Baim Inst for Clinical Res, Boston, MA; Deepak L Bhatt, Brigham and Women's Hosp, Boston, MA; Mikhail N Kosiborod, Saint Luke's Mid America Heart Inst and Univ of Missouri-Kansas City, Kansas City, MO

3:00 PM

Board # 3149

Clinical Characteristics and Outcomes of Atrial Fibrillation Patients With Thrombocytopenia: The Fushimi AF Registry

**Kenjiro Ishigami** , Yuya Aono, Syuhei Ikeda, Kyoto Medical Ctr, Kyoto, Japan; Kosuke Doi, Kyoto Medical Ctr, Fushimi-ku, Kyoto, Japan; Yoshimori An, Mitsuru Ishii, Moritake Iguchi, Nobutoyo Masunaga, Hisashi Ogawa, Kyoto Medical Ctr, Kyoto, Japan; Hiromichi Wada, Natl Hosp Org Kyoto Medical Ctr, Kyoto, Japan; Koji Hasegawa, Kyoto Medical Ctr NHO, Kyoto, Japan; Mitsuru Abe, Kyoto Medical Ctr NHO, Kyoto, Japan, Kyoto, Japan; Masaharu Akao, Kyoto Medical Ctr, Kyoto, Japan

3:00 PM

Board # 3150

Low Volume Catheterization Labs Have a Higher Rate of Transradial Access Adoption During Cardiac Procedures at Veterans Affairs Hospitals

**Kristine Beaver** , VA Puget Sound Health Care System, Seattle, WA; Adhir Shroff, Univ Illinois at Chicago, Chicago, IL; Javier Valle, VA Eastern Colorado Health Care System, Denver, CO; Rajesh Swaminathan, Durham VA Medical Ctr, Durham, NC; Mladen Vidovich, Univ Illinois at Chicago, Chicago, IL; Diana Naranjo, Univ of Washington, Seattle, WA; Arnold Seto, VAMC Long Beach, Long Beach, CA; Samir Pancholy, Wilkes-Barre VAMC, Wilkes-Barre, PA; Christian Helfrich, VA, Seattle, WA; Sunil Rao, Duke Univ Medical Ctr, Durham, NC

3:00 PM

Board # 3151

Applications of a Specialty Bicuspid Aortic Valve Program: Clinical Continuity and Translational Collaboration

**Erin Crawford** , Patrick M McCarthy, Jyothy Puthumana, Northwestern Univ Feinberg Sch of Med and Northwestern Memorial Hosp, Chicago, IL; Paul Fedak, Cumming Sch of Med, Univ of Calgary, Libin Cardiovascular Inst of Alberta, Calgary, AB, Canada; Michael Markl, Northwestern Univ Feinberg Sch of Med & McCormick Sch of Engineering, Chicago, IL; Menghan Liu, Adin-Cristian Andrei, Northwestern Univ Feinberg Sch of Med, Chicago, IL; Jane Kruse, Charles Davidson, S Chris Malaisrie, Northwestern Univ Feinberg Sch of Med and Northwestern Memorial Hosp, Chicago, IL

3:00 PM

Board # 3152

Association Between the Presence and Extent of Coronary Artery Disease and Atrial Fibrillation: Insights From the Life-heart Study

**Jelena Kornej** , Sylvia Henger, Ralph Burkhardt, Univ of Leipzig, Leipzig, Germany; Holger Thiele, Univ Leipzig - Heart Ctr, Leipzig; Joachim Thiery, Univ Hosp Leipzig, Leipzig; Markus Scholz, Univ of Leipzig, Leipzig, Germany

3:00 PM

Board # 3153

Clinical Significance of Elevated Preprocedural Hemoglobin Level as a Marker of Outcomes After Percutaneous Coronary Intervention

**Byung Gyu Kim** , Sanggye Paik Hosp, Inje Univ Coll of Med, Seoul, Korea, Republic of; Byeong-Keuk Kim, Sung-Jin Hong, Chul-Min Ahn, Dong-Ho Shin, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang, Severance Cardiovascular Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Byoung Kwon Lee, Gangnam Severance Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of

3:00 PM

Board # 3155

Physician Preferences for Oral Anti-coagulation for Obese & Non-obese Patients With Non-valvular Atrial Fibrillation

**Jigar Rajpura** , Amol Dhamane, Bristol-Myers Squibb, Lawrenceville, NJ; Deborah Goldschmidt, Analysis Group, New York, NY; Elyse Swallow, Analysis Group, Boston, MA; Cristina Russ, Pfizer, New York, NY; Mauricio Ferri, Bristol-Myers Squibb, Lawrenceville, NJ

3:00 PM

Board # 3156

Predictors of In-hospital Mortality in Elderly Patients With Heart Failure

**Jigar J Patel** , The George Washington Univ Sch of Med and Health Sciences, Washington, DC; Talal Alzahrani, The George Washington Univ, Arlington, VA; Angela Ryan, Joseph Krepp, The George Washington Univ Sch of Med and Health Sciences, Washington, DC

# Abstract Poster Session

## LF.APS.06 - Clinical Risk Scores and Biomarkers

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 3175

Does Ones Socioeconomic Status Predispose to the Development of Stress Induced Cardiomyopathy?

**Kareem Niazi** , Stavros Zinonos, Rutgers RWJ Medical Sch, New Brunswick, NJ; John B Kostis, William J. Kostis, Rutgers Robert Wood Johnson Medical Sch, New Brunswick, NJ; John Kassotis, Rutgers RWJ Medical Sch, New Brunswick, NJ

3:00 PM

Board # 3176

A Novel Protein Sampling Method Using Styrene Maleic Acid is Non-destructive to Cardiovascular Cells and Tissues

**Andrew John Smith** , Kathleen E Wright, Stephen P Muench, Sophie Schumann, Adrian Whitehouse, Karen E Porter, John Colyer, Univ of Leeds, Leeds, United Kingdom

3:00 PM

Board # 3177

No Association Between Plasma Kinin B1 Receptor Levels and Coronary Artery Disease

Yoshimi Kishimoto, Ochanomizu Univ, Tokyo, Japan; Masayuki Aoyama, Tokyo Medical Ctr, Tokyo, Japan; Emi Saita, Ochanomizu Univ, Tokyo, Japan; Yukinori Ikegami, Tokyo Medical Ctr, Tokyo, Japan; Kazuo Kondo, Ochanomizu Univ, Tokyo, Japan; **Yukihiko Momiyama** , Tokyo Medical Ctr, Tokyo, Japan

3:00 PM

Board # 3178

Predicting New-Onset Post-Operative Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Grafting Using a Multiple Logistic Regression Analysis

**Anshul B Parulkar** , Brown Univ, Rhode Island Hosp, Providence, RI; Wasiq Sheikh, Rhode Island Hosp, Providence, RI; Malik Ahmed, Brown Univ, Dedham, MA; Esseim Sharma, Brian Daniel McCauley, Sanchita Parulkar, Brown Univ, Providence, RI; Lauren Rousseau, Cardiovascular Inst, Providence, RI; Antony F Chu, Brown Univ, Providence, RI

3:00 PM

Board # 3179

Skewness but Not Kurtosis of Red Cell Corpuscular Volume Nullifies the Predictive Ability of Red Cell Distribution Width for Predicting All-Cause Mortality

**Benjamin D Horne** , Intermountain Medical Ctr and Univ of Utah, Salt Lake City, UT; Joseph B Muhlestein, Intermountain Medical Ctr; Univ of Utah, Murray, UT; Sterling T Bennett, Joseph B Muhlestein, Kurt R Jensen, Diane Marshall, Raymond McCubrey, T. Jared Bunch, Intermountain Medical Ctr, Salt Lake City, UT; Tami L Bair, Intermountain Medical Ctr, Salt Lake Cty, UT; Viet T LE, Donald L Lappé, Intermountain Medical Ctr, Salt Lake City, UT; Jeffrey L Anderson, Intermountain Medical Ctr and Univ of Utah, Murray, UT; Kirk Ute Knowlton, Intermountain Medical Ctr and Univ of California at San Diego, Salt Lake City, UT

3:00 PM

Board # 3180

Total Thrombus-formation Analysis System Predicts High Bleeding Risk in Patients With Coronary Artery Disease and Hemodialysis

**Nobuhiro Nakanishi** , Koichi Kaikita, Kumamoto Univ, Kumamoto, Japan; Masanobu Ishii, Kumamoto Univ, Kumamoto, Japan, AL; Yu Oimatsu, Tatsuro Mitsuse, Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

3:00 PM

Board # 3181

Prognostic Impact of Comorbidity in Heart Failure With Reduced, Mid-range and Preserved Left Ventricular Ejection Fraction Admitted for Acute Decompensated Heart Failure; A Prospective Study of OPAR (Osaka Prefectual Acute Heart Failure Registry)

**Kiyomi Kayama** , Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masahiro Seo, Osaka General Medical Ctr, Osaka City, Japan; Makoto Abe, Jun Nakamura, Kyoko Yamamoto, Osaka General Medical Ctr, Osaka, Japan; Masatsugu Kawahira, Osaka General Medical Ctr, Oosaka, Japan; Kazuya Tanabe, Masatake Fukunami, Osaka General Medical Ctr, Osaka, Japan

3:00 PM

Board # 3182

The Branched-chain Amino Acids Valine and Leucine Predict All-cause Mortality in Cardiovascular Disease Patients Independently From the Presence of Type 2 Diabetes Mellitus

Axel Muendlein, Andreas Leiherer, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; **Christoph H Saely** , Private Univ of the Principality of Liechtenstein, Triesen, Liechtenstein; Alexander Vonbank, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Marc Schindewolf, Joern F Dopheide, Iris Baumgartner, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland; Arthur Mader, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Peter Fraunberger, Medical Central Labs, Feldkirch, Austria; Heinz Drexel, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland

3:00 PM

Board # 3183

Plasma Xanthine Oxydoreductase (XOR) Activity in Patients Who Require Cardiovascular Intensive Care

**Yusaku Shibata** , Akihiro Shirakabe, Nippon Medical Sch Chiba Hokusoh Hosp, Chiba, Japan; Hirotake Okazaki, Nippon Medical Sch, Chiba, Japan; Masato Matsushita, Nippon Medical Sch Chiba Hokusoh Hosp, Inzai, Japan; Hiroki Goda, Syouta Shigihara, Kazuhiro Asano, Nippon Medical Sch Chiba Hokusoh Hosp, Chiba, Japan; Takayo Murase, Takashi Nakamura, Sanwa Kagaku Kenkyusho Co., Ltd, Mie, Japan; Nobuaki Kobayashi, Nippon Medical Sch Chiba Hokusoh Hosp, Chiba, Japan; Noritake Hata, Nippon Medical Sch, Chiba, Japan; Kuniya Asai, Nippon Medical Sch Chiba Hokusoh Hosp, Tokyo, Japan; Wataru Shimizu, Nippon Medical Sch, Tokyo, Japan

3:00 PM

Board # 3184

High Plasma Levels of Legumain in Patients With Complex Coronary Lesions

Tomohiko Umei, Tokyo Medical Ctr, Tokyo, Japan; Yoshimi Kishimoto, Ochanomizu Univ, Tokyo, Japan; Masayuki Aoyama, Tokyo Medical Ctr, Tokyo, Japan; Emi Saita, Ochanomizu Univ, Tokyo, Japan; Yukinori Ikegami, Tokyo Medical Ctr, Tokyo, Japan; Kazuo Kondo, Ochanomizu Univ, Tokyo, Japan; **Yukihiko Momiyama** , Tokyo Medical Ctr, Tokyo, Japan

3:00 PM

Board # 3185

Biomarkers of Inflammation and Fibrosis in the Young Adults With History of Kawasaki Disease

**Shinsuke Hoshino** , Chisato Shimizu, Samantha C Roberts, Lori B Daniels, Adriana H Tremoulet, John B Gordon, Jane C Burns, Univ of California San Diego, San Diego, CA

3:00 PM

Board # 3186

The Correlation Between Clinical Syntax Score II and Carotid Intima-media Thickness in Patients With Stable Coronary Artery Disease

Mahmoud Abdelnabi, Abdallah Almaghraby, Alexandria Univ, Alexandria, Egypt; **Yehia Saleh** , Michigan State Univ, East Lansing, MI; Ahmed Morsi, Fayoum Univ, Fayoum, Egypt; Tuğba Öz, Medipol Üniversitesi Çamlıca Hastanesi, East Lansing, Turkey; Ola Abdelkarim, Alexandria Univ, Alexandria, Egypt; Khader Herzallah, Layan El-khatib, Michigan State Univ, East Lansing, MI; Haitham Badran, Ain Shams Univ, Cairo, Egypt

# Abstract Poster Session

## EP.APS.14 - Cohort Studies II

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 3062

Coronary Revascularization Trends in the United States, 2000-2014

**Hua Hao** , Univ of Southern California, Los Angeles, CA; Varun Pattisapu, Cedars-Sinai Medical Ctr, Los Angeles, CA; Yong Cen, David Shavelle, Univ of Southern California, Los Angeles, CA

3:00 PM

Board # 3063

Predictive Ability of Positive Risk Enhancing Factors and Coronary Artery Calcium Scoring in the Multi-Ethnic Study of Atherosclerosis

**Vincent A Pallazola** , Johns Hopkins Univ, Baltimore, MD; Vasanth Sathiyakumar, Johns Hopkins Hosp, Baltimore, MD; Oluseye Ogunmoroti, Nazir Savji, Johns Hopkins Univ, Baltimore, MD; Michael Y Tsai, Univ Minnesota, Minneapolis, MN; Kiang Liu, Northwestern Univ, Chicago, IL; Mary Cushman, Univ Vermont, Colchester, VT; Joseph Yeboah, Wake Forest Univ, Winston-Salem, NC; Michael J Blaha, Roger S Blumenthal, Seth S Martin, Johns Hopkins Hosp, Baltimore, MD

3:00 PM

Board # 3064

Serum Uric Acid Level in Younger Age and Physical Disability in Older Age - The Chicago Heart Association Detection Project in Industry (CHA) 40 Year Follow-Up Health Survey

Tzuo-Yun Lan, Kiang Liu, Northwestern Univ, Chicago, IL; Martha L Daviglus, Univ Illinois Chicago, Chicago, IL; Daniel Garside, Univ of Illinois at Chicago, Chicago, IL; Donald M Lloyd-Jones, **Thanh-Huyen T Vu** , Northwestern Univ, Chicago, IL

3:00 PM

Board # 3065

Greater Than the Sum of Its Parts: The Risk of Future Cardiovascular Disease (CVD) in Patients With Type 2 Diabetes (T2D), Prior Cardiovascular Disease or Both

**Vincent J Willey** , Chi Nguyen, HealthCore, Wilmington, DE; Effie Kuti, Rakesh Luthra, Boehringer Ingelheim, Ridgefield, CT

3:00 PM

Board # 3066

Frequency and Predictors of Discontinuation With Non-vitamin K Antagonist Oral Anticoagulants in Patients With Non-valvular Atrial Fibrillation: A Population-based Study

**Luis Alberto Garcia Rodriguez** , CEIFE, Madrid, Spain; Yanina Balabanova, Pareen Vora, Bayer AG, Berlin, Germany; Gunnar Brobert, Bayer AB, Stockholm, Sweden; Ana Ruigomez, CEIFE, Madrid, Spain

3:00 PM

Board # 3067

Proximity to an Advanced Heart Failure Center and County Heart Failure Mortality

**Khansa Ahmad** , Edward Chen, Umair Nazir, Brown Univ, Providence, RI; Sebhat Erqou, Univ of Pittsbrugh, Pittsburgh, PA; Wen-Chih Hank Wu, Providence VA Hosp, Providence, RI

3:00 PM

Board # 3068

Low-Density Lipoprotein-Cholesterol Lowering in Real-World Patients Treated With Evolocumab

**Nihar R Desai** , Yale Sch of Med, New Haven, CT; Rolin L Wade, IQVIA, Plymouth Meeting, PA; Pin Xiang, Amgen Inc, Thousand Oaks, CA; Sasikiran Nunna, Xin Wang, IQVIA, Plymouth Meeting, PA; Jason Exter, Mohdhar Habib, Stefan DiMario, Amgen Inc, Thousand Oaks, CA; Chi-Chang Chen, IQVIA, Plymouth Meeting, PA

3:00 PM

Board # 3069

Cardiovascular Anthropometry Best Suited for Large Scale Population Screening in Sub Saharan Africa

**Basil N Okeahialam** , Hadiza A Agbo, Ayuba I Zoakah, Jos Univ Teaching Hospit, Jos Plateau, Nigeria

3:00 PM

Board # 3070

Increase of the Burden of Hospitalized Aortic Stenosis and Decrease of Its Intervention-associated Mortality Since the Implementation of Transcatheter Aortic Valve Implantation in the Province of Quebec, Canada

**Philipp Frieden** , Quebec Heart Inst, Québec, QC, Canada; Claudia Blais, Institu Natl De Sante, Quebec, QC, Canada; Denis Hamel, Philippe Gamache, Inst national de santé publique du Québec, Quebec, QC, Canada; Philippe Pibarot, IUCPQ-UL, Quebec, QC, Canada; Marie Annick Clavel, Quebec Heart Inst, Quebec, QC, Canada

3:00 PM

Board # 3071

Subclinical Myocardial Injury and Cardiovascular Mortality: Racial Differences in Prevalence and Risk (From the Third National Health and Nutrition Examination Survey)

**Stephen T Broughton** , UPMC Heart and Vascular Inst, Pittsburgh, PA; Jared W Magnani, Univ of Pittsburgh, Pittsburgh, PA; Elsayed Z Soliman, Muhammad Ahmad, Wake Forest Sch of Med, Winston Salem, NC

# Abstract Poster Session

## HF.APS.26 - Concepts on Pericarditis and Myocarditis

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2327

Use of Cardiac MRI to Assess Response to Therapy of Pericarditis

**Mitra M. Patel** , Ann Morgenstern, Brandon M Mikolich, Sharon Regional Medical Ctr, Sharon, PA; J Ronald Mikolich, Northeast Ohio Medical Univ, Youngstown, OH

3:00 PM

Board # 2328

New Onset Heart Failure Due to Effusive Constrictive Pericarditis

**Yousif Al-Saiegh** , Pennsylvania Hosp, Philadelphia, PA; Philip Williams, Univ of Pennsylvania, Philadelphia, PA; Timothy Barry, Pennsylvania Hosp, Phila, PA; Elias Impens, Jenna Spears, Sina Manthey, Pennsylvania Hosp, Philadelphia, PA

3:00 PM

Board # 2329

Nationwide Inpatient Outcomes of Pericardial Tamponade in Patients With Autoimmune Diseases

**Muhammad Mohsin Furqan** , Yasser Al-Khadra, Cleveland Clinic Fndn, Cleveland, OH; Johnny Chahine, Cleveland Clinic Fairview Hosp, Cleveland, OH; Mohamed Khayata, Cleveland Clinic, Strongsville, OH; Beni R Verma, Cleveland Clinic, Cleveland, OH; Chandra Kanth Ala, Cleveland Clinic, Troy, MI; Paul Cremer, Cleveland Clinic, Cleveland, OH; M Chadi Alraies, Wayne State Univ, Detroit Medical Ctr, Detroit, MI; Allan L Klein, Cleveland Clinic, Cleveland, OH

3:00 PM

Board # 2330

A Mood Stabilizer Inflames the Pericardium

**Wajdi Bader** , Muhammad Siddiqui, Mohammad Alaoua, Marshfield Clinic, Marshfield, WI; Jasmine Botello, Indiana Univ, South Bend, IN

3:00 PM

Board # 2331

Tuberculous Pericarditis in the United States- Trends and Associations From the Healthcare Utilization Project Nationwide Inpatient Sample Database

**Neiberg Lima** , Duncan Vos, Christopher Stancic, Mireya Diaz, Rheanne Maravelas, Ricardo de Castro, Thomas Melgar, Western Michigan Univ Homer Stryker MD Sch of Med, Kalamazoo, MI

3:00 PM

Board # 2332

Intensification of the Inflammasome Formation in the Pericardium of Patients With Chronic Severe Pericarditis

**Aldo Bonaventura** , Virginia Commonwealth Univ, Richmond, VA; Antonio Cannata, Azienda Sanitaria Univria Integrata (ASUITS) and Univ of Trieste, Trieste, Italy; Eleonora Mezzaroma, Virginia Commonwealth Univ, Henrico, VA; Gianfranco Sinagra, Rossana Bussani, Azienda Sanitaria Univria Integrata (ASUITS) and Univ of Trieste, Trieste, Italy, Trieste, Italy; Stefano Toldo, Virginia Commonwealth Univ, Glen Allen, VA; Rohan Gandhi, Myoungjoo Kim, Kiniksa Pharmaceuticals Corp, Lexington, MA; John Paolini, Kiniksa Pharmaceuticals Corp., Lexington, MA; Fabrizio Montecucco, Univ of Genoa, Genoa, Italy; Antonio Abbate, VCU Pauley Heart Ctr, Virginia Commonwealth Univ, Richmond, VA; Adolfo Gabriele Mauro, Virginia Commonwealth Univ, Richmond, Virginia, VA

3:00 PM

Board # 2333

Clinical Predictors of the Need for Pericardial Window or Recurrent Effusion Following Therapeutic Pericardiocentesis

**Daniel O Johnsrud** , Akshar Jaglan, Aurora Sinai/St. Luke's Medical Ctrs, Univ of Wisconsin Sch of Med and Public Health, Milwaukee, WI; Ana Perez Moreno, Advocate Aurora Health, Milwaukee, WI; Suhail Q. Allaqaband, M. Fuad Jan, Aurora Sinai/St. Luke's Medical Ctrs, Univ of Wisconsin Sch of Med and Public Health, Milwaukee, WI

3:00 PM

Board # 2334

Outcomes and Etiologies for 30-day Readmissions in Patients With Myocarditis

**Bing Yue** , Claire Huang Lucas, Chayakrit Krittanawong, Lingling Wu, Eyal Herzog, Mount Sinai St. Luke's-West Hosp, New York, NY

3:00 PM

Board # 2335

Prediction of Fat and Fibrotic Invasion in the Left Ventricular Myocardium Using Four-dimensional Cardiac Computed Tomography in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy

**Nobusada Funabashi** , Yoshio Kobayashi, Chiba Univ, Chiba, Japan

3:00 PM

Board # 2336

Cardiovascular Complications Related to Zika Virus

**Victor G Becerra Gonzales** , Univ of Miami/Jackson Memorial Hosp, Miami, FL; Paola Lichtenberger, Joel Fishman, Yoel Siegel, Eduard Ghersin, Barry E Hurwitz, Claudia Martinez, Univ of Miami, Miami, FL

# Abstract Poster Session

## CH.APS.15 - Congenital Heart Disease

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 4061

Long Term Antihypertensive Medication After Effective Stent Implantation For Aortic Coarctation

**Rui Anjos** , Mariana Lemos, Odete Mingas, Susana Cordeiro, Hosp de Santa Cruz, Lisboa, Portugal

3:00 PM

Board # 4062

Accuracy of Transthoracic Echocardiography in the Anatomic Description of Double Outlet Right Ventricle in Patients Undergoing Biventricular Repair

**Jessica Tang** , The Children's Hosp of Philadelphia, Philadelphia, PA; Jamie K Harrington, Boston Children's Hosp, Boston, MA; Heather Griffis, Children's Hosp of Philadelphia, Roberts' Building, Philadelphia, PA; Antara Mondal, Christopher Mascio, Paul M Weinberg, Children's Hosp of Philadelphia, Philadelphia, PA; Andrew J Powell, Boston Children's hospital, Boston, MA; Meryl S Cohen, CHOP, Philadelphia, PA

3:00 PM

Board # 4063

Principle Component Analysis of Flow Propagation Through Fontan Circulation Identifies Characteristics Associated With Single Ventricle Functional Performance

**Michal Schafer** , Benjamin Frank, UC Denver - Anschutz Medical C, Aurora, CO; Max B Mitchell, Univ of Colorado, Aurora, CO; James Jaggers III, Childrens Hosp Colorado, Aurora, CO; Lorna Browne, Children's Hosp Colorado, Aurora, CO; Alex Barker, UC Denver - Anschutz Medical C, Aurora, CO; Gareth Morgan, Univ of Colorado - Children's, Aurora, CO; Kendall S Hunter, The Childrens Hosp, Aurora, CO; Dunbar D Ivy, Univ of Colorado, Aurora, CO; Adel K Younoszai, Childrens Hosp Colorado, Aurora, CO; Michael Di Maria, UC Denver - Anschutz Medical C, Aurora, CO

3:00 PM

Board # 4064

Ductus Diameter and Left Pulmonary Artery End-Diastolic Velocity at 3 Days of Age May Predict Future Needs of Surgical Closure for Patent Ductus Arteriosus in Preterm Infants : A Post Hoc Analysis of Prospective Multicenter Cohort Study

**Satoshi Masutani** , Saitama Medical Univ, Saitama-ken, Japan; Tetsuya Isayama, Tohru Kobayashi, Masashi Mikami, Kyongsun Pak, Natl Ctr for Child Health and Development, Tokyo, Japan; Katsuaki Toyoshima, Kanagawa Children's Medical Ctr, Yokohama, Japan; Patent Ductus Arteriosus and Left Atrial Size Evaluation in Preterm Infants (PLASE) Study Group

3:00 PM

Board # 4065

A Fetal Risk Stratification Protocol for Postnatal Development of Coarctation of the Aorta: A Quality Improvement Initiative

**Shiraz Arif Maskatia** , Stanford Univ Medical Sch, Palo Alto, CA; David M Kwiatkowski, Lucile Packard Stanford, Palo Alto, CA; Shazia Bhombal, Alexis Davis, Stanford Univ Medical Sch, Palo Alto, CA; Doff B McElhinney, Stanford Univ Medical Ctr, Palo Alto, CA; Theresa Tacy, Stanford Univ, Palo Alto, CA; Amy Quirin, Stanford Univ Medical Ctr, Palo Alto, CA; Rajesh Punn, Stanford Univ Medical Sch, Palo Alto, CA

3:00 PM

Board # 4066

Comparative Analysis of Measured vs. Estimated VO2 in Sedated, Spontaneously Breathing Congenital Cardiac Catheterization Patients

**Stephan Juergensen** , UCSF, Benioff Children's Hosp, San Francisco, CA; Shalin Parekh, UCSF, San Francisco, CA; Amy Iams, UCSF Benioff Children's Hosp, San Francisco, CA; Phillip Moore, UCSF, San Francisco, CA

3:00 PM

Board # 4067

Time of Exposure to Shunt, Surgical Timing and Prematurity Are Risk Factors for Pulmonary Vein Stenosis in Trisomy 21 Patients With Atrioventricular Canal or Septal Defects

**Connie Choi** , Abbas Zaidi, Kimberlee Gauvreau, Boston Children's Hosp, Boston, MA; Kathy Jennifer Jenkins, Boston Childrens Hosp, Boston, MA; Ming Hui Chen, Boston Children's Hosp, Boston, MA

3:00 PM

Board # 4068

Pulmonary Vein Atresia: Transcatheter Interventions and Long-Term Outcomes

**Varun Aggarwal** , Univ of Minnesota Masonic Children's Hosp, Minneapolis, MN; Gary E Stapleton, Baylor Coll Med, Houston, TX; Henri Justino, Texas Children's Hosp, Houston, TX

3:00 PM

Board # 4069

Where the Fontan Flows: Longitudinal Trends in Flow Through the Palliated Single Ventricle Circulation

**Reena Maria Ghosh** , Kevin K Whitehead, Matthew A Harris, Sara Partington, Children's Hosp of Philadelpia, Philadelphia, PA; David M Biko, Children's Hosp of Phladelphia, Philadelphia, PA; Mark Alan Fogel, Children's Hosp of Philadelpia, Philadelphia, PA

3:00 PM

Board # 4070

Comparison of Drug Coated Balloon and Plain Balloon Angioplasty for the Treatment of Pulmonary Vein Stenosis After Total Anomalous Pulmonary Venous Connection Repair

**Toshikatsu Tanaka** , Michio Matsuoka, Yasunobu Miki, Kobe Children's Hosp, Kobe, Japan

3:00 PM

Poster Professor

Mark Alan Fogel, Philadelphia, PA

# Abstract Poster Session

## IN.APS.12 - Controversies in TAVR and Circulatory Assist Devices

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 4192

**In-Hospital and 30-Day Outcomes Following Acute Mechanical Circulatory Support With Impella 5.0** ® **/LD** ® **Device: An Updated Systematic Review and Meta-Analysis**

Rupak Desai, Atlanta VA Medical Ctr, Decatur, GA; **Upenkumar Patel** , Nassau Univ Medical Ctr, East Meadow, NY; Sandeep Singh, Amsterdam Univ Medical Ctr, Amsterdam; Tarang Parekh, George Mason Univ, Fairfax, VA; Muhammad Uzair Lodhi, Eastern Idaho Regional Med Ctr, Idaho Falls, ID; Kishorbhai Gangani, Texas Health Arlington Memorial, Arlington, TX; Rajesh Sachdeva, Morehouse Sch of Med & Emory Sch of Med, Atlanta VA Medical Ctr, Atlanta, GA; Gautam Kumar, Emory Univ Sch of Med, Atlanta VA Medical Ctr, Decatur, GA

3:00 PM

Board # 4193

Outcomes of TAVR in Patients With Cirrhosis: Report From National Inpatient Sample

**Omid Behnamfar** , John H. Stroger, Jr. Hosp of Cook County, Chicago, IL; Moinuddin Syed, Cook County Health, Chicago, IL

3:00 PM

Board # 4194

Higher Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios Are Associated With Postoperative Atrial Fibrillation Following Transcatheter Aortic Valve Insertion

**David Jin** , St Vincent's Hosp Melbourne, Melbourne, Australia; Arul Baradi, St Vincent's Hosp, Melbourne, Australia; Rohan Navani, St Vincent's Health, Melbourne, Melbourne, Australia; Sarah Brazel, Robert Whitbourn, St Vincent's Hosp Melbourne, Melbourne, Australia; Arthur Nasis, Monash Health, Melbourne, Australia; Andrew M Wilson, St Vincent's Hosp, Fitzroy, Australia; Sonny Palmer, St Vincent's Hosp Melbourne, Melbourne, Australia

3:00 PM

Board # 4195

Transcatheter Aortic Valve Replacement Reduces Inpatient Costs and Length of Stay for Cancer Patients With Severe Aortic Stenosis

**Logan Hostetter** , Dominique Monlezun, Tariq Thannoun, Krishna Pabba, Sean M Lawless, Ritesh Patel, Cullen Grable, Danyi Zheng, Natalie Chen, McGovern Medical Sch at The Univ of Texas Health Science Ctr at Houston, Houston, TX; Nicolas Palaskas, Juan Lopez-Mattei, Peter Kim, The Univ of Texas MD Anderson Cancer Ctr, Houston, TX; Mehmet Cilingiroglu, Arkansas Heart Hosp, Little Rock, AR; Konstantinos Marmagkiolis, Pepin Heart Inst, Florida Hosp Tampa, Tampa, FL; Cezar Iliescu, The Univ of Texas MD Anderson Cancer Ctr, Houston, TX

3:00 PM

Board # 4196

Minimalistic Approach in Tavr Protects Against Postoperative Delirium, Mechanical Ventilation and Prolonged ICU Stay

**Alexander Maier** , Peter Stachon, Benedikt Hammerich, Heart Ctr Freiburg Univ, Freiburg, Germany; Frank Humburger, Brieschal Thomas, Univ Hosp Freiburg, Freiburg, Germany; Timo Heidt, Univ Heart Ctr Freiburg, Freiburg; Wolfgang Bothe, Holger Schröfel, M Zehender, Heart Ctr Freiburg Univ, Freiburg, Germany; Jochen Reinöhl, Univ Hosp Freiburg, Freiburg i. Br.; Christoph Bode, Heart Ctr Freiburg Univ, Freiburg, Germany; Klaus Kaier, Faculty of Med and Medical Ctr-Univ of Freiburg, Freiburg, Germany; Constantin Von Zur Muehlen, Heart Ctr Freiburg Univ, Freiburg, Germany

3:00 PM

Board # 4197

Reduction in Stroke Rates With Embolic Protection Device During Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis

**Samarthkumar Jayeshkumar Thakkar** , Rochester General Hosp, Rochester, NY; Ashish Kumar, Saint Johns Medical Coll Hospita, Bangalore, India; Jay Shah, Mercy Saint Vincent Medical Ctr, Toledo, OH; Nageshwara Gullapalli, Univ of Nevada Reno SOM, Reno, NV; Perwaiz M Meraj, North Shore Univ Hosp, Manhasset, NY; Rajkumar Prakashbhai Doshi, Univ of Nevada Reno SOM, Reno, NV

3:00 PM

Board # 4198

Variability in Pacemaker Implantation in the 3M TAVR Study: Indications, Outcomes and Implications

Janarthanan Sathananthan, St. Paul's Hosp, Vancouver, BC, Canada; John Webb, St Paul's Hosp, Vancouver, BC, Canada; Dale J Murdoch, Sandra B Lauck, John A Cairns, St. Paul's Hosp, Vancouver, BC, Canada; Karin H Humphries, Providence Healthcare Res Inst, Vancouver, BC, Canada; Richard C Cook, Univ of British Columbia, Vancouver, BC, Canada; Robert C Welsh, Mazankowski Alberta Heart Inst, Edmonton, AB, Canada; Jonathon Leipsic, UBC, Vancouver, BC, Canada; Philipp Blanke, St. Paul's Hosp, Vancouver, BC, Canada; Anson Cheung, Univ of British Columbia, Vancouver, BC, Canada; Jian Ye, St. Paul Hosp, Vancouver, BC, Canada; Philippe Genereux, Mark Hensey, **Madeleine Barker** , St. Paul's Hosp, Vancouver, BC, Canada; Benjamin Tyrrell, Mazankowski Heart Inst, Edmonton, AB, Canada; Faisal Al-Qoofi, Libin Cardiovascular Inst of Alberta, Calgary, AB, Canada; James Velianou, Hamilton General Hosp, Hamilton, ON, Canada; Madhu K Natarajan, Hamilton Health Sciences - General, Hamilton, ON, Canada; Harindra C Wijeysundera, Sunnybrook Health Sciences Ctr, Toronto, ON, Canada; Sam Radhakrishnan, Univ of Toronto, Toronto, ON, Canada; Eric Horlick, Toronto General Hosp, Toronto, ON, Canada; Mark Osten, Peter Munk Cardiac Ctr, Toronto, ON, Canada; Christopher E Buller, St Michaels Hosp, Toronto, ON, Canada; Mark D Peterson, Univ of Toronto, Toronto, ON, Canada; Anita W Asgar, Inst de Cardiologie de Montreal, Montreal, QC, Canada; Donald Palisaitis, Hôpital du Sacré-Coeur de Montréal, Montreal, QC, Canada; Jean-Bernard Masson, St. Pauls Hosp, Vancouver, BC, Canada; Susheel K Kodali, Columbia Univ Medical Ctr, New York; Tamim Nazif, Columbia Univ Medical Ctr, New York, NY; Vinod H Thourani, Medstar Washington Hosp Ctr, Washington, DC; Vasilis Babaliaros, Emory Univ, Atlanta, GA; David J Cohen, Univ of Missouri-Kansas City, Kansas City, MO; Martin B Leon, Columbia Univ Medical Ctr, New York, NY; David Alexander Wood, Ctr for Heart Valve Innovation, Vancouver, BC, Canada

3:00 PM

Board # 4199

Hospital Variation in Use of Impella for Acute Myocardial Infarction Not Explained by Patient Factors

**Michael P Thompson** , Donald S Likosky, John D Syrjamaki, Thomas Cascino, Keith D Aaronson, Univ of Michigan, Ann Arbor, MI; Jonathan Haft, Univ Michigan, Ann Arbor, MI; Francis D Pagani, Univ of Michigan, Ann Arbor, MN

3:00 PM

Board # 4200

Feasibility of Transcatheter Aortic Valve Replacement in Patients With Bicuspid Aortic Valve

**Yuta Tsujisaka** , Toshiaki Toyota, Natsuhiko Ehara, Kitae Kim, Takeshi Kitai, Misun Pak, Yasuhiro Sasaki, Atsushi Kobori, Makoto Kinoshita, Shuichiro Kaji, Yutaka Furukawa, Kobe City Medical Ctr General Hosp, Kobe, Japan

3:00 PM

Board # 4201

Paradoxical Increase of Stroke in Patients With Primary Hemostasis Disorders Following Transcatheter Aortic Valve Replacement

**Kensuke Matsushita** , Benjamin Marchandot, Marion Kibler, Joe Heger, Marilou Peillex, Antonin Trimaille, Sebastien Hess, Lelia Grunebaum, Mickael Ohana, Antje Reydel, Laurence Jesel, Nouvel Hôpital Civil, Strasbourg, France; Sophie Susen, Eric Van Belle, CHU Lille, Univ de Lille, Lille, France; Patrick Ohlmann, Olivier Morel, Nouvel Hôpital Civil, Strasbourg, France

# Abstract Poster Session

## IN.APS.11 - Controversies in Vascular Intervention: From Drug-Coated Devices to Total Occlusions

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 4178

Statins Bring the Prognostic Impact Only in Peripheral Artery Disease Patients With Elevated C-reactive Proteins

**Eiji Shibahashi** , Tokyo Women's Medical Univ Medical Ctr East, Tokyo, Japan; Kentaro Jujo, Tokyo Women's Medical Univ, Tokyo, Japan; Keiko Mizobuchi, Tokyo Women's Medical Univ, Tokyo, Japan; Masashi Nakao, Tokyo Women's Medical Univ, Tokyo, Japan; Shinichi Nunoda, Tokyo Women's Medical Univ Medical Ctr East, Tokyo, Japan; Nobuhisa Hagiwara, Tokyo Women's Medical Univ, Tokyo, Japan

3:00 PM

Board # 4179

Easily Penetrated Aorto-iliac Chronic Total Occlusion is Associated With Poor Clinical Outcome After Endovascular Treatment: Subanalysis of a Multicenter Prospective Registry in Japan

**Yoshito Kadoya** , Kan Zen, Graduate Sch of Medical Science Kyoto Prefectur, Kyoto, Japan; Osamu Iida, Kansai Rosai Hosp, Amagasaki, Japan; Yoshito Yamamoto, Tokorozawa Heart Clinic, Saitama, Japan; Daizou Kawasaki, Morinomiya Hosp, Osaka, Japan; Yasutaka Yamauchi, Takatsu General Hosp, Kanagawa, Japan; Yoshiaki Shintani, Takatsu General Hosp, Kanagawa, Japan, Kurume, Japan; Teruyasu Sugano, Yokohama City Univ, Yokohama, Japan; Hiroyoshi Yokoi, Kokura Memorial Hosp, Kitakyusyu, Japan; Satoaki Matoba, Kyoto Prefectural Univ of Med, Kyoto, Japan; Masato Nakamura, Toho university, Ohashi medical Cen, Tokyo, Japan; on behalf of the OMOTENASHI Investigators

3:00 PM

Board # 4180

The Impact of Multidisciplinary Care Including Nurse Practitioner on Wound Healing in Patients With Chronic Limb-threatening Ischemia With Tissue Loss

**Yosuke Hata** , Osamu Iida, Mitsutoshi Asai, Masaharu Masuda, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Kansai Rosai Hosp, Amagasaki, Japan; Takashi Kanda, Kansai Rosai Hosp, Amagasaki Hyogo, Japan; Takuya Tsujimura, Shota Okuno, Kansai Rosai Hosp, Amagasaki, Japan; Yasuhiro Matsuda, Kansai Rosai Hosp Cardiovascular Ctr, Amagasaki, Japan; Toshiaki Mano, Kansai Rosai Hosp, Suita, Japan

3:00 PM

Board # 4181

Endovascular Reconstruction From Aortic Valve to Aortic Arch Using One-piece Valved-fenestrated-bifurcated Endografting in Animal Experiments

**Jiaxuan Feng** , Xianhao Bao, Tao Li, Yuxi Zhao, Yiming Li, Mingwei Wu, Aikebaierjiang Ainiwaer, Jian Zhou, Zaiping Jing, Changhai Hosp, Shanghai, China

3:00 PM

Board # 4182

The Prognostic Impact of Congestive Heart Failure on Peripheral Artery Disease Intervention Outcomes: Nationwide Insight

**Abdalla Hassan** , UMass Medical Sch, Worcester, MA; Ashraf Abugroun, Hussein Daoud, AIMMC, Chicago, IL; Shafaq Mahmoud, Alvaro Alonso, UMass Medical Sch, Worcester, MA

3:00 PM

Board # 4183

Sex Differences and Impact on Peripheral Artery Disease Intervention Outcomes From a Nationwide Data: More Significant Than We Think

**Abdalla Hassan** , UMass Medical Sch, Worcester, MA; Ashraf Abugroun, Hussein Daoud, AIMMC, Chicago, IL; Shafaq Mahmoud, Alvaro Alonso, UMass Medical Sch, Worcester, MA

3:00 PM

Board # 4184

Distal Particulate Embolization May Occur in Critical Limb Ischemia Patients After Femoral Artery Treatment With Drug-coated Balloons: A Histopathological Assessment

**Katsumi Inoue** , Kokura Memorial Hosp, Kitakyushu, Japan; Yosuke Hata, Kansai Rosai Hosp, Amagasaki, Japan; Nobuhiro Ito, Tomoi Yusuke, Yoshimitsu Soga, Kokura Memorial Hosp, Kitakyushu, Japan; Osamu Iida, Kansai Rosai Hosp, Amagasaki, Japan; Kenji Ando, Kokura Memorial Hosp, Kitakyushu, Japan; Takeshi Kimura, Kyoto Univ Graduate Sch of Med, Kyoto, Japan

3:00 PM

Board # 4185

Clinical Outcomes of Stent-graft Versus Polymer-free, Paclitaxel-coated Stent Implantation for Patients With Peripheral Artery Diseases Presenting Femoropopliteal Artery Lesions

**Takuya Tsujimura** , Osamu Iida, Mitsutoshi Asai, Masaharu Masuda, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takashi Kanda, Shota Okuno, Yasuhiro Matsuda, Yosuke Hata, Jaya Kanduri, Kansai Rosai Hosp, Amagasaki, Japan

3:00 PM

Board # 4187

Bayes Factor Meta-analysis of the Mortality Claims for Peripheral Paclitaxel-eluting Devices

**John A Bittl** , AdventHealth Ocala, Ocala, FL; Yulei He, Univ of Maryland Univ Coll, Largo, MD; Usman Baber, Mount Sinai Medical Ctr, New York, NY; Robert L Feldman, AdventHealth Ocala, Ocala, FL; Gregory O Von Mering, UAB Univ Hosp, Birmingham, AL; Sanjay Kaul, Cedars-Sinai Medical Ctr, Los Angeles, CA

3:00 PM

Board # 4188

Complications and Mortality With Use of Intra-Aortic Balloon Pump vs Impella in Patients Presenting With ST - Elevation Myocardial Infarction

**Saad M Amin** , WVU Berkeley Medical Ctr, Martinsburg, WV; Harsh Mehta, Saint Barnabas Medical Ctr, Livingston, NJ; Akhtar Amin, Univ of Texas Health Science Ctr San Antonio, San Antonio, TX

3:00 PM

Board # 4189

Effectiveness of Catheter Directed Thrombolysis for Massive and Submassive Pulmonary Embolism Compared to Systemic Thrombolysis or No Thrombolysis

**Abhinav C Krishnan** , Dhruvil A Patel, Christina Reji, Mahir Elder, Vijaya Arun Kumar, Wayne State Univ, Detroit, MI

3:00 PM

Board # 4190

Impact of Chronic Kidney Disease on the Outcomes of Patients Undergoing Semi- Urgent and Elective Percutaneous Coronary Intervention

**Mayank Dalakoti** , Ching-Hui Sia, Natl Univ Heart Ctr, Singapore, Singapore; Rui-Huai Lau, Pei-Ying Ho, Yong Loo Lin Sch of Med, Singapore, Singapore; Tiong-Cheng Yeo, Huay-Cheem Tan, Mark YY Chan, Joshua PY Loh, Natl Univ Heart Ctr, Singapore, Singapore

3:00 PM

Board # 4191

Clinical Characteristics and Outcomes of Patients With Differing Haemoglobin Levels Undergoing Semi-Urgent and Elective Percutaneous Coronary Intervention

**Mayank Dalakoti** , Ching-Hui Sia, Natl Univ Heart Ctr, Singapore, Singapore; Pei-Ying Ho, Rui-Huai Lau, Yong Loo Lin Sch of Med, Singapore, Singapore; Tiong-Cheng Yeo, Huay-Cheem Tan, Mark YY Chan, Joshua PY Loh, Natl Univ Heart Ctr, Singapore, Singapore

# Abstract Poster Session

## IN.APS.10 - Coronary Imaging, Physiology and Beyond

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 4169

A Novel Ticagrelor Coated Stent to Eliminate the Need for Dual Anti Platelet Therapy Post PCI

**Jared D Romeo** , Univ of Pittsburgh, Pittsburgh, PA; John Pacella, Univ Pittsburgh, Pittsburgh, PA; Ellen S Gawalt, Duquesne Univ, Pittsburgh, PA

3:00 PM

Board # 4170

Systematic Review and Meta-Analysis of Noninvasive Angiographically-Derived Virtual Fractional Flow Reserve (vFFR)

**Saarik Gupta** , Gayatri Suresh Kumar, Univ of Louisville, Louisville, KY; Abdur R Khan, Univ Of Louisville, Louisville, KY; Shahab Ghafghazi, Shahab Ghafghazi, Louisville, KY

3:00 PM

Board # 4171

Thin-Strut Bioresorbable Scaffold Promotes Rapid Arterial Healing Through Endothelial Shear Stress-Mediated Immune Modulation: A Serial Multi-Modal Optical Coherence Tomography-Near Infrared Fluorescence (OCT-NIRF) Molecular Imaging Study

**Sunwon Kim** , Korea Univ Ansan Hosp, Ansan, Korea, Republic of; Hyun-Sang Park, KAIST, Daejeon, Korea, Republic of; Hyeong Soo Nam, Hanyang Univ, Seoul, Korea, Republic of; Joon Woo Song, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Jeongmoo Han, Hanyang Univ, Seoul, Korea, Republic of; Jae Won Ahn, Chung-Ang Univ, Anseong, Korea, Republic of; Gyounghwan Kim, KAIST, Daejeon, Korea, Republic of; Yeon Hoon Kim, Hanyang Univ, Seoul, Korea, Republic of; Hongki Yoo, KAIST, Daejeon, Korea, Republic of; Kyeongsoon Park, Chung-Ang Univ, Anseong, Korea, Republic of; Wang-Yuhl Oh, KAIST, Daejeon, Korea, Republic of; Jin Won Kim, Korea Univ Guro Hosp, Seoul, Korea, Republic of

3:00 PM

Board # 4172

A Novel Percutaneous Approach for Deployment of 3D Printed Coronary Implants in Swine Models of Ischemic Heart Disease

**John Hollowed** , Caroline Colbert, UCLA, Los Angeles, CA; Jesse Currier, VA Medical Ctr West Los Angeles, Los Angeles, CA; Kim-lien Nguyen, UCLA, Los Angeles, CA

3:00 PM

Board # 4173

A Novel Calcium Parameter, Calcium Ratio, Can Predict Minimum Lumen Area in Calcified Lesions: Optical Coherence Tomographic Study

**Yutaka Matsuhiro** , Masami Nishino, Kyosuke Yanagawa, Hitoshi Nakamura, Koji Yasumoto, Akihiro Tanaka, Yasuharu Matsunaga, Naotaka Okamoto, Masamichi Yano, Masaki Yamato, Yasuyuki Egami, Ryu Shutta, Jun Tanouti, Osaka Rousai Hosp, Sakai, Japan

3:00 PM

Board # 4174

Effectiveness of Hybrid Nano-Coating for the Next-Generation Drug-Eluting Stents Technology

**Terumitsu Hasebe** , Tokai Univ Hachioji Hosp, Hachioji, Tokyo, Japan; Shunto Maegawa, Tomohiro Matsumoto, Tokai Univ Hachioji Hosp, Hachioji Tokyo, Japan; Nami Nishimura, Nishimura Heart Clinic, Ageo, Saitama, Japan; Masao Nishimura, Nishimura Heart Clinic, Ageo Saitama, Japan

3:00 PM

Board # 4175

Clinical Outcomes After Treatment of Coronary Bifurcation Lesions Guided by Fractional Flow Reserve

**Dobrin Iotkov Vassilev** , Kiril Karamfiloff, Niya Mileva, Pavel Nikolov, Alexandrovska Univ Hosp, Sofia, Bulgaria

3:00 PM

Board # 4176

Safety of First in Human Triple-Gene Therapy Candidate for Heart Failure Patients

Ewa Jaruga-Killeen, Intrexon, West Palm Beach, FL; David A. Bull, Banner Univ Medical Ctr, Tuscon, AZ; Kapildeo Lotun, Banner Univ Medical Ctr, Tucson, AZ; Timothy D. Henry, Gregory Egnaczyk, The Christ Hosp, Cincinnati, OH; Thomas D Reed, Intrexon, West Palm Beach, FL; **Amit N. Patel** , Univ of Utah-Bioengineering, SLC, UT

3:00 PM

Poster Professor

Habib Samady, Atlanta, GA

3:00 PM

Board # 4177

**Dynamic Vessel Bioreactor Recapitulates** in vivo **Cell Viability and Phenotype in Response to Absorbable Magnesium-Based Stent**

**Juan Wang** , Mehmet H Kural, Jonathan Wu, Yale Univ, New Haven, CT; Guangxin Li, New Haven, CT; Katherine Leiby, New Haven, CT, New Haven, CT; Nan Huang, Southwest Jiaotong Univ, Chengdu; Laura Elizabeth Niklason, Yale Univ, New Haven, CT

# Abstract Poster Session

## DD.APS.01 - Drug Discovery and Targets in LV Dysfunction

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 1150

In vitro **Drug Screening Model for Cardiac Fibrosis Using Human Induced Pluripotent Stem Cell Derived Cardiac Tissue Provides Drug Repositioning of Anti-fibrotic Drugs for Cardiac Fibrosis**

**Hiroko Iseoka** , Osaka Univ, Osaka, Japan; Shigeru Miyagawa, Osaka Univ, Suita, Japan; Yoshiki Sakai, Akima Harada, Yoshiki Sawa, Osaka Univ, Osaka, Japan

3:00 PM

Board # 1151

3D Light Sheet Imaging of Left Anterior Descending Artery Ligation-Induced Myocardial Infarction in Mice

**Urmas Roostalu** , Nora Elisabeth Zois, Philip G. j. Pedersen, Tanja Xenia Pedersen, Niels Vrang, Jacob Hecksher Sorensen, Gubra ApS, Hørsholm, Denmark

3:00 PM

Board # 1152

C53: An Innovative GC-B Activating Drug Targeting Cardiorenal Fibrosis and the Progression to CKD-induced Heart Failure

**Yang Chen** , Seethalakshmi R Iyer, Gerald E Harders, Jacob J Schaefer, Tomoko Ichiki, John C Burnett, Jeson Sangaralingham, Mayo Clinic, Rochester, MN

3:00 PM

Board # 1153

Identification of Small Molecules That Ameliorate Morphological Abnormalities of Hypertrophic Cardiomyopathy in Human IPS Cell-Derived Cardiomyocytes

**Kohei Deguchi** , Shigeru Kondo, Ayaka Sakoda, Kenichi Imahashi, Takeda Pharmaceutical Company, Fujisawa, Japan; Kenji Miki, CiRA Kyoto Univ, Kyoto, Japan; Tomoyuki Nishimoto, Takeda Pharmaceutical Company, Fujisawa, Japan; Tsukasa Sugo, GenAhead Bio.Inc, Fujisawa, Japan; Yoshinori Yoshida, Kyoto Univ, Kyoto, Japan

3:00 PM

Board # 1154

Pro-Compliant Effects of Mavacamten Are Preserved in the Setting of β-adrenergic Receptor Blockade: In vivo and ex vivo Evidence

Sunny Sun, Brian S Ferguson, **Carlos L del Rio** , MyoKardia, San Francisco, CA

3:00 PM

Board # 1155

New Inhibitor of p38-alpha MAPK Ameliorates Pulmonary Hypertension Induced by Sugen/Hypoxia in Rats

**Gisele Zapata-Sudo** , Grazielle F Silva, Allan K Alencar, Marina M de Moraes Carvalho da Sil, Jaqueline S Da Silva, Rosana C Freitas, Tadeu L Montagnoli, Carlos A Fraga, Univ Federal Rio de Janeiro, Rio de Janeiro, Brazil; Roberto T Sudo, Univ Federal do Rio de Janeiro, Rio de Janeiro, Brazil

3:00 PM

Board # 1156

Right and Left Global Longitudinal Strain in Heart Failure With Preserved Ejection Fraction Predicts Outcome for Patients Treated by Sodium-Glucose Cotransporter 2 Inhibitors

**Takaaki Sakai** , Ichijyukai NISHIO Hosp, Nogata, Japan; Shinichiro Miura, Fukuoka Univ Sch of Med, Fukuoka, Japan

# Abstract Poster Session

## IM.APS.10 - Echocardiography: Systolic and Diastolic Function

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 4107

Direct Estimation of Ejection Fraction and Longitudinal Strain From 2-Dimensional Echocardiography Videos Using Convolutional Neural Networks

**Shinichi Goto** , Calum A Macrae, Rahul C Deo, One Brave Idea/Brigham and Women's Hosp, Boston, MA

3:00 PM

Board # 4108

Assessment of Relative Pressure Gradient as a Novel Parameter Derived From Vector Flow Mapping in Heart Failure Patients

**Yuko Soyama** , Maria Karmpalioti, Peter Huntjens, Nobuyuki Kagiyama, Washington Univ in St. Louis, Saint Louis, MO; Masataka Sugahara, Pittsburgh, PA; Justin M Vader, Washington Univ, Saint Louis, MO; John Gorcsan III, Washington Univ at St. Louis, Saint Louis, MO

3:00 PM

Board # 4109

Machine Learning Prediction of Human Interpretable Local Features on Echocardiogram

**David Ouyang** , Stanford, Menlo Park, CA; Amirata Ghorbani, Stanford, Palo Alto, CA; Jonathan H Chen, Robert A Harrington, Euan A Ashley, David Liang, Stanford Univ, Stanford, CA; James Zou, Stanford, Palo Alto, CA

3:00 PM

Board # 4110

Is Diastolic Dysfunction Grading Useful In AL-Amyloidosis? Insights From A Cohort Of 1,405 Patients

**Yehia Ali** , Vidhu Anand, Rosalyn Adigun, Sorin Pislaru, Angela Dispenzieri, Martha Grogan, Mayo Clinic, Rochester, MN; Garvan Kane, Mayo Fndn, Rochester, MN; Patricia A Pellikka, Mayo Clinic Coll Med, Rochester, MN; Cristina Pislaru, Mayo Clinic Coll of Med, Rochester, MN

3:00 PM

Board # 4111

Preoperative Right Atrial Structure and Function are Predictive of Severe Right Ventricular Failure After Left Ventricular Assist Device

**Maria Karmpalioti** , Washington Univeristy in St. Louis, st. louis, MO; Yuko Soyama, Washington Univ in St. Louis, Saint Louis, MO; Peter Huntjens, Washington Univ in St. Louis, St Louis, MO; David Raymer, Barnes Jewish Hosp, St. Louis, MO; Shane LaRue, Washington Univ Sch Of Med, St. Louis, MO; Akinobu Itoh, Washington Univ Sch of Med, Saint Louis, MO; Justin M Vader, Washington Univ, Saint Louis, MO; John Gorcsan III, Washington Univ at St. Louis, Saint Louis, MO

3:00 PM

Board # 4112

The Inclusion of Pulmonary Arterial Pressure Confounds the Detection of Diastolic Dysfunction Using the Current American Society of Echocardiography Guidelines in Pre-Capillary Pulmonary Hypertension

**Amr Telmesani** , Jean Deschamps, Ahmed AlTurki, Jewish General Hosp, Montreal, QC, Canada; Fox Benjamin, Shamir (Assaf Harofeh), Tel Aviv, Israel; Igal Sebag, Robert Schlesinger, Jonathan Afilalo, Mark Eisenberg, Ali Abualsaud, David Langleben, Lawrence Rudski, Jewish General Hosp, Montreal, QC, Canada

3:00 PM

Board # 4113

Machine Learning Prediction of Left Ventricular Chamber Size and Ejection Fraction

**David Ouyang** , Stanford, Menlo Park, CA; Amirata Ghorbani, Stanford, Palo Alto, CA; Jonathan H Chen, Robert A Harrington, Stanford Univ, Stanford, CA; James Zou, Stanford, Palo Alto, CA; Euan A Ashley, David Liang, Stanford Univ, Stanford, CA

3:00 PM

Board # 4114

Sex and Race Differences in Cardiac Structure and Function in Late Life: The Atherosclerosis Risk in Communities (ARIC) Study

Alvin Chandra, Hicham Skali, Brian Claggett, Brigham and Women's Hosp, Boston, MA; Joseph Rossi, Univ of North Carolina, Sanford, NC; Stuart D Russell, Duke Univ Medical Ctr, Raleigh, NC; Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD; Dalane Kitzman, Wake Forest Baptist Health, Winston-Salem, NC; Suma H Konety, Univ Minnesota, Minneapolis, MN; Thomas Mosley, Univ MS Medical Ctr, Jackson, MS; Scott D Solomon, **Amil M Shah** , Brigham and Women's Hosp, Boston, MA

3:00 PM

Board # 4115

Cumulative Blood Pressure From Mid-to-late Life and Late Life Cardiac Structure and Function: The Atherosclerosis Risk in Communities (ARIC) Study

**Kanako Teramoto** , St. Marianna Univ Sch of Med, Kawasaki, Japan; Wilson Nadruz Jr., Univ of Campinas, Sao Paulo, Brazil; Kunihiro Matsushita, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Brian Claggett, Jenine E John, Hicham Skali, Scott D Solomon, Brigham and Women's Hosp, Boston, MA; Susan Cheng, Cedars Sinai Hosp, Los Angeles, CA; Amil M Shah, Brigham and Women's Hosp, Boston, MA

3:00 PM

Board # 4116

Ablation of Atrial Fibrillation Improves Left Ventricular Diastolic Function and Prevents HFpEF-Related Hospitalization in Super-Elderly Patients

**Naoko Ikeda** , Showa Univ Koto-Toyosu Hosp, tokyo, Japan; Tomoko S Kato, Hiroto Fukuoka, Showa Univ Koto Toyosu Hosp, Tokyo, Japan; Kohei Wakabayashi, Showa Univ Koto-Toyosu, Tokyo, Japan; Kaoru Tanno, Showa Univ Koto Toyosu Hosp, Tokyo, Japan

3:00 PM

Poster Professor

Wendy Tsang, Toronto, ON, Canada

# Abstract Poster Session

## IM.APS.11 - Echocardiography: Techniques and Technology

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 4117

Real-Time Noninvasive Intra-Cardiac Pressure Estimation Using Subharmonic Signals From Ultrasound Contrast Agents

**Cara Esposito** , Priscilla Machado, Maureen McDonald, Praveen Mehrotra, Michael P Savage, David L Fischman, Ira Cohen, Nicholas J Ruggiero, Paul Walinsky, Oleg Vishnevsky, Andrew Boyle, Marguerite Davis, Flemming Forsberg, Thomas Jefferson Univ, Philadelphia, PA; Kristopher Dickie, Clarius Mobile Health, Burnaby, BC, Canada; Jaydev K. Dave, Thomas Jefferson Univ, Philadelphia, PA

3:00 PM

Board # 4118

**Ultrasound Contrast Agents Enhance** in vivo **Delivery of Mir-302b Mimics and Antimir-34a to Mouse Hearts**

Meghan R Otto, Mariah C Priddy, Lauren A Higgins, Joseph B Moore IV, Marcin Wysoczynski, Roberto Bolli, **Jonathan A Kopechek** , Univ of Louisville, Louisville, KY

3:00 PM

Board # 4119

Reversible Endothelial Membrane Perforation for Targeted Drug/Gene Delivery Using Ultrasound and Microbubbles

**Brandon Helfield** , Concordia Univ, Montreal, QC, Canada; Xucai Chen, Simon Watkins, Univ of Pittsburgh, Pittsburgh, PA; Flordeliza S Villanueva, UPMC, Pittsburgh, PA

3:00 PM

Board # 4120

Antitumor Efficacy and Reduced Cardiotoxicity Using Ultrasound Mediated Delivery of Liposomal Doxorubicin Conjugated-Microbubbles

**Mingyu He** , Francois Yu, Xucai Chen, Linda Lavery, Univ of Pittsburgh, Pittsburgh, PA; Flordeliza S Villanueva, UPMC, Pittsburgh, PA

3:00 PM

Board # 4121

Can the Rope Score be Used as a Triaging Tool in Assessing the Need for Saline Contrast Study in Stroke Workup to Identify Patent Foramen Ovale ?

**Aditya Singh** , Fortune Ojeanor, Guneet Ahluwalia, Karthikeyan Ananthasubramaniam, Henry Ford Hosp, Detroit, MI

3:00 PM

Board # 4122

Noninvasive Estimation of Left Ventricular End-diastolic Pressure Using Left Atrial Area Strain Obtained by Transthoracic 3D Speckle Tracking Echocardiography in Patients With Coronary Artery Disease

**Tomoyuki Banno** , Nagoya City Univ, Nagoya, Aichi, Japan; Kazuaki Wakami, Shohei Kikuchi, Nagoya City Univ, Nagoya, Japan; Hiroshi Fujita, Nagoya City Univ, Nagoya, Aichi, Japan; Toshihiko Goto, Nagoya City Univ, Nagoya, Japan; Hidekatsu Fukuta, Nagoya City Univ Medical Sch, Nagoya, Japan; Yoshihiro Seo, Nobuyuki Ohte, Nagoya City Univ, Nagoya, Japan

3:00 PM

Board # 4123

Stress Myocardial Elastography for Improved Ischemia and Infarction Detection

**Jad El Harake** , Vincent Sayseng, Columbia Univ, New York, NY; Julien Grondin, Columbia Univ Medical Ctr, New York, NY; Rachel Weber, Columbia Univ, New York, NY; Kathleen R Flaherty, Sabahat Bokhari, Columbia Univ Medical Ctr, New York, NY; Elisa Konofagou, Columbia Univ, New York, NY

3:00 PM

Board # 4124

Assessment of Left Ventricular Ejection Fraction From Echocardiographic Images Using Deep Learning Algorithm

**Kenya Kusunose** , Akihiro Haga, Takashi Abe, Daiju Fukuda, Tokushima Univ Hosp, Tokushima, Japan; Hirotsugu Yamada, Tokushima Univ Hosp, Naruto, Japan; Masataka Sata, Tokushima Univ Grad Sch, Tokushima, Japan

3:00 PM

Board # 4125

Automated Guidance and Image Capture of Echocardiographic Views Using a Deep Learning-Derived Technology

**Baljash Cheema** , Northwestern Univ Feinberg Sch of Med, Chicago, IL; Ching Hsieh, David Adams, Bay Labs, Inc., San Francisco, CA; Akhil Narang, Northwestern Univ Feinberg Sch of Med, Chicago, IL; James D Thomas, Northwestern, Chicago, IL

3:00 PM

Board # 4126

Screening Echocardiography With Remote Reading by Telemedicine as a Risk Stratification Tool in Primary Care: Data From the PROVAR+ Study

**Bruno R Nascimento** , Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Adriana C Diamantino, Rua Herculano De Freitas 151, Belo Horizonte Mg, Brazil; Maria Do Carmo Pereira Nunes, UFMG, Belo Horizonte, Brazil; Craig A Sable, Children's Natl Medical Ctr, Potomac, MD; Kaciane Oliveira, Hosp das Clínicas da UFMG, Belo Horizonte, Brazil; Lara Rabelo, Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Marcia Barbosa, Hosp Socor, Belo Horizonte, Brazil; Alison T Reese, Children's Natl Health System, Washington, DC; Clara Fraga, Waydder Costa, Breno Rezende, Joao Pedro Rios, Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Susana Reis, Hosp das Clínicas, Belo Horizonte, Brazil; Andrea Z Beaton, Cincinnati Children's Hosp Medical Ctr, Cincinatti, OH; Antonio L Ribeiro, UFMG, Belo Horizonte, Brazil

3:00 PM

Poster Professor

Mani A Vannan, Atlanta, GA

# Abstract Poster Session

## EA.APS.21 - Electrophysiology and Arrhythmias III

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2143

**SUMOylation of the Cardiac Sodium Channel Na** V **1.5 Modifies Inward Current and Cardiac Excitability**

**Jin-Young Yoon** , Alex Greiner, Julia Jacobs, William J. Kutschke, Young-Rae Kim, Daniel S Matasic, Gina M Morgan, Haider Mehdi, Kaikobad Irani, Barry London, Univ of Iowa Carver Coll of Med, Iowa City, IA

3:00 PM

Board # 2144

Atrial Cardiomyocyte-Specific Pitx2c Overexpression Impaired Sinus Node Function

**Shunsuke Baba** , Toru Akaike, Susumu Minamisawa, Satoko Shinjo, The Jikei Univ Sch of Med, Tokyo, Japan

3:00 PM

Board # 2145

Machine Learning of Remodeled Ventricular Action Potentials and Long-Term Follow-Up of Ventricular Arrhythmias

**Albert J Rogers** , Mahmood Alhusseini, Stanford Univ, Palo Alto, CA; Anojan Selvalingam, Stanford Univ Medical Ctr, Stanford, CA; David Edward Krummen, UC San Diego, San Diego, CA; Firas Abuzaid, Stanford Univ, Stanford, CA; Junaid A Zaman, Stanford Univ, London, CA; Tina Baykaner, Stanford Univ, Palo Alto, CA; Paul Clopton, Peter Bailis, Matei Zaharia, Stanford Univ, Stanford, CA; Sanjiv M Narayan, Stanford Med, Stanford, CA

3:00 PM

Board # 2146

Mechanical Esophageal Displacement for Esophageal Safety of Mechanical Esophageal Displacement for Esophageal Thermal Injury Prevention During Atrial Fibrillation Ablation in Swine

**Renner Pereira** , Insto do Coração - Univ de São Paulo, São Paulo, Brazil; Cristiano Faria Pisani, Heart Inst- Incor, Sao Paulo, Brazil; Vera Aiello, Insto do Coração - HCFMUSP, São Paulo, Brazil; Idagene A Cestari, Heart Inst Univ of Sao Paulo, Sao Paulo, Brazil; Daniel Moura, Muhieddine Chokr, Carina Hardy, Melo Sissy, Insto do Coração - Univ de São Paulo, São Paulo, Brazil; Mauricio Scanavacca, Univ of Sao Paulo, São Paulo, Brazil; Denise Hachul, Heart Inst - SP Univ, Sao Paulo, Brazil

3:00 PM

Board # 2147

Enhanced Efficiency of Atrial Fibrillation Conversion to Sinus Rhythm by Inhaled Flecainide HPbCD Formulation Revealed by Concentration-time Area Analysis

**Giovanna C. Pedreira** , Beth Israel Deaconess Medical Ctr, Boston, MA; Sofia A. Medeiros, Beth Israel Deaconess Medical Cente, Boston, MA; Fernanda Tessarolo Silva, Alexandre Bortolotto, Bruna Araujo Silva, Beth Israel Deaconess Medical Ctr, Boston, MA; Alexandre Marum, Beth Israel Deaconess, Boston, MA; Bruce Nearing, Beth Israel Deaconess Medical Centr, Boston, MA; Prashanti Madhavapeddi, InCarda Therapeutics Inc, Newark, CA; Michael Hurrey, InCarda Therapeutics, Newark, CA; Carlos Schuler, InCarda Therapeutics, Inc, Newark, CA; Luiz Belardinelli, InCarda Therapeutics Inc., Newark, CA; Richard Verrier, Beth Israel Deaconess Medical Ctr, Boston, MA

3:00 PM

Board # 2148

Acacetin is a Promising New Pharmacologic Agent for Suppression of Life-threatening Arrhythmias Associated With the Brugada and Early Repolarization Syndromes

**Hector Barajas** , Lankenau Inst for Medical Res, Wynnewood, PA; Jose Di Diego, Lankenau Inst for Medical Rese, Wynnewood, PA; Bence Patocskai, Univ of Heidelberg, Heidelberg, Germany; Virág Borbáth, Univ of Heidelberg, Mannheim, Germany; Gui-Rong Li, Medical Coll of Xiamen Univ, Fujian, China; Dan Hu, Renmin Hosp of Wuhan Univ, Wuhan; Alexander Burashnikov, Lankenau Inst Medical Res, Wynnewood, PA; Charles N Antzelevitch, Lankenau Inst for Medical Res, Penn Valley, PA

3:00 PM

Board # 2149

Structural and Electrophysiological Maturation of Human Induced Pluripotent Stem Cell Derived Atrial Cardiomyocytes to Serve as a Platform to Model Atrial Fibrillation

**Olivia T Ly** , Univ of Illinois COM, Chicago, Chicago, IL; Seock Won Youn, Grace Brown, Univ of Illinois, Chicago, Chicago, IL; Liang Hong, Univ of Illinois at Chicago, Chicago, IL; Arvind Sridhar, Univ of Illinois, Chicago, Chicago, IL; Meihong Zhang, Univ of Illinois at Chicago, Chicago, IL; Zain Alzahrani, Univ of Illinois in Chicago, Chicago, IL; Salman Khetani, Univ of Illinois, Chicago, Chicago, IL; Dawood Darbar, Univ of Illinois, Chicago, IL

3:00 PM

Board # 2150

Microrna-1 Biophysically Modulates Cardiac Electrophysiology via Direct Binding to Kir2.1

**Dandan Yang** , Ohio State Univ, Columbus, OH

3:00 PM

Board # 2151

Blunting of Electrophysiological Effects of Isoproterenol in a Tissue Model of Arrhythmogenic Cardiomyopathy

**Robert N Hawthorne** , Adriana Blazeski, Justin Lowenthal, Deborah DiSilvstre, Kenneth R Boheler, Johns Hopkins Univ, Baltimore, MD; Gordon F Tomaselli, Albert Einstein Coll of Med, Bronx, NY; Leslie Tung, Johns Hopkins Univ, Baltimore, MD

3:00 PM

Board # 2152

**Caveolin-3 Remodeling in Heart Failure and Implications for β2-adrenergic Regulation of** IK1

**Louise Reilly** , Kunal Sondhi, Hannah C Waldman, Sara Abozeid, Lee L Eckhardt, Univ of Wisconsin-Madison, Madison, WI

3:00 PM

Board # 2153

**Elucidating the Mechanisms for Arrhythmogenicity in Ventricular Myocytes From Alpha MHC** 403/+ **Hypertrophic Hearts**

Henrietta Cserne Szappanos, The Univ of Western Australia, Crawley, Australia; Danica W Ito, Rose E Dixon, Univ of California Davis, Davis, CA; **Livia C Hool** , The Univ of Western Australia, Crawley Perth, Australia

3:00 PM

Board # 2154

Impact of Functional Studies on Exome Sequence Variant Interpretation in Early-onset Cardiac Conduction System Diseases

**Kenshi Hayashi** , Akihiro Nomura, Kanazawa Univ, Kanazawa, Japan; Ryota Teramoto, Kanazawa Univ Hosp, Kanazawa, Japan; Yoshihiro Asano, Osaka Univ, Suita Osaka, Japan; Manu Beerens, BWH - Harvard Medical Sch, Boston, MA; Yasutaka Kurata, Kanazawa Medical Univ, Uchinada, Japan; Noboru Fujino, Kanazawa Univ Hosp, Kanazawa, Japan; Hiroshi Furusho, Kenji Sakata, Kanazawa Univ, Kanazawa, Japan; Eva P Buys, Massachusetts General Hosp, Charlestown, MA; Patrick Y Sips, Ghent Univ, Ghent, Belgium; Micah L Burch, Kelly E. Amy, Brigham and Women's Hosp and Harvard Medical Sch, Boston, MA; Takeshi Kato, Kanazawa Univ, Kanazawa, Japan; Akira Funada, Kanazawa Univ Hosp, Kanazawa, Japan; Hayato Tada, Chiaki Nakanishi, Toyonobu Tsuda, Hirofumi Okada, Kanazawa Univ, Kanazawa, Japan; Calum A Macrae, Brigham and Women's Hosp, Boston, MA; Seiji Takashima, Osaka Univ, Suita, Japan; Masakazu Yamagishi, Osaka Univ of Human Sciences, Settsu, Japan; Masa-aki Kawashiri, Masayuki Takamura, Kanazawa Univ, Kanazawa, Japan

3:00 PM

Board # 2155

**Oxidative Injury Contributes to Electrical Remodeling in Atrial Fibrillation by Leading to the Emergence of a Constitutively Active Form of** IKACh

**Shin Yoo** , Northwestern Univ, Chicago, IL; Anna Pfenniger, Northwestern Memorial Hosp, Chicago, IL; Wenwei Zhang, Trent Waugh, Suzanne Bull, Northwestern Univ, Chicago, IL; Georg Gussak, Feinberg Cardiovascular Res Inst, Chicago, IL; Bradley P Knight, Nortwestern Medical Ctr, Chicago, IL; Rod Passman, Andrew Wasserstrom, Gary L Aistrup, Rishi Arora, Northwestern Univ, Chicago, IL

# Abstract Poster Session

## EP.APS.16 - Epidemiology of Inflammatory, Infiltrative & Latrogenic Cardiovascular Conditions

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 3084

Acute Perforation Rate With the Micra Transcatheter Pacemaker in a Real-World Medicare Population: A Comparison to the Clinical Trial Experience

Kael Wherry, Medtronic, Mounds View, MN; **Kurt Stromberg** , Medtronic, Moundsview, MN; Lindsay Bockstedt, Medtronic, Minneapolis, MN; Jennifer Hinnenthal, Medtronic, Mounds View, MN; Mikhael F El-Chami, Emory Univ, Atlanta, GA

3:00 PM

Board # 3085

Pacing Threshold Predicts Survival in Patients With Pacemaker and Chemotherapy: A Retrospective Trial

**Martin Riesenhuber** , Andreas Spannbauer, Medical Univ of Vienna, Vienna, Austria; Friedrich Rauscha, AKH Wien, Vienna; Herwig Schmidinger, Univ.-Klinik for Innere Med. II, Vienna, Austria; Adelinde Boszotta, Thomas Pezawas, Medical Univ of Vienna, Vienna, Austria; Christoph Schukro, Medical Univ of Vienna, Vienna; Marianne Gwechenberger, Univ. of Vienna, Vienna, Austria; Günter Stix, Anahit Anvari, Thomas Wrba, Medical Univ of Vienna, Vienna, Austria; Cesar Saul Khazen, Vienna Medical Univ, Vienna; Martin Andreas, Medical Univ of Vienna, Vienna; Günther Laufer, Christian Hengstenberg, Medical Univ of Vienna, Vienna, Austria; Mariann Gyongyosi, Medical Univ of Vienna, Vienna

3:00 PM

Board # 3086

Trends in Infection Burden for Cardiac Implantable Electric Devices and the Impact of Socioeconomic Status (1999 to 2014)

**Ameesh Isath** , Stuthi Perimbeti, Ashish Correa, Bharat Narasimhan, Karan Sud, Mount Sinai St. Luke's West, New York, NY; Deepak Padmanabhan, Mayo Clinic, Rochester, MN; Davendra Mehta, Mount Sinai St. Luke's, New York, NY

3:00 PM

Board # 3087

Role of Patent Foramen Ovale Closure in Migraines : A Review of the National Inpatient Database (1999-2014)

**Ameesh Isath** , Stuthi Perimbeti, Bharat Narasimhan, Ashish Correa, Karan Sud, Nikhil Bachoo, Mount Sinai St. Luke's West, New York, NY; Deepak Padmanabhan, Mayo Clinic, Rochester, MN; Eyal Herzog, Mount Sinai St. Luke's, New York, NY

3:00 PM

Board # 3088

Impact of Cied Infection: A Clinical and Economic Analysis of the Wrap-It Study

**Bruce L. Wilkoff** , Cleveland Clinic, Chagrin Falls, OH; Giuseppe Boriani, Univ of Modena and Reggio Emilia, Modena, Emilia-Romagna, Italy; Suneet Mittal, Valley Health System, Ridgewood, NJ; Jeanne E. Poole, Univ of Washington, Seattle, WA; Charles Kennergren, Sahlgrenska Univ Hosp, Göteborg, Sweden; G. Ralph Corey, Duke Clinical Res Insitute, Durham, NC; John C. Love, Maine Medical Ctr, Portland, ME; Ralph Augostini, Ohio State Univ, Columbus, OH; Svein Faerestrand, Univ of Bergen and Haukeland Univ Hosp, Bergen, Norway; Sherman Scott Wiggins, ARK-LA-TEX Cardiology, Shreveport, LA; Jeff S. Healey, McMaster Univ, Hamilton, ON, Canada; Reece Holbrook, Jeff D. Lande, Sarah A. Willey, Medtronic, Mounds View, MN; Khaldoun G. Tarakji, Cleveland Clinic, Cleveland, OH

3:00 PM

Board # 3089

High Rates of Cerebral Infarction & Mortality in Patients With Infective Endocarditis Involving Mitral Annular Calcification

Aaron A. H. Smith, **Alexander J. Baxa** , Joseph D. Steffens, Jorge Reyes-Castro, Holly Rodin, Richard W. Asinger, Hennepin Healthcare, Minneapolis, MN

3:00 PM

Board # 3090

Real-World Clinical Characteristics and Recurrence Burden of Patients Diagnosed With Recurrent Pericarditis in the United States

**David Lin** , Abbott Northwestern Hosp, Minneapolis, MN; Christine Majeski, Abbott Northweatern Hosp, Minneapolis, MN; Maral DerSarkissian, Analysis Group, Inc., Boston, MA; Matt Magestro, Kiniksa Pharmaceuticals Corp., Lexington, MA; Cristi Cavanaugh, Analysis Group, Inc., Boston, MA; François Laliberté, Dominique Lejeune, Malena Mahendran, Groupe d'analyse, Ltée, Montreal, QC, Canada; Mei Sheng Duh, Analysis Group, Inc., Boston, MA

3:00 PM

Board # 3091

Demographic Characteristics of Medicare Beneficiaries With Diagnosis of Wild-Type Amyloidosis Cardiomyopathy

Jose Nativi-Nicolau, Univ of Utah, Salt Lake City, UT; **Maria Cecilia Vieira** , Marianna Bruno, Pfizer, New York City, NY; Yong Chen, Pfizer, Collegeville, PA; Rebecca Levin, Jose Alvir, Pfizer, New York City, NY; Daniel P Judge, Medical Univ of South Carolina (MUSC), Charleston, SC

3:00 PM

Board # 3092

Burden of Arrhythmia in Patients With Takotsubo Cardiomyopathy (tcm) From the Nationwide Inpatient Sample:2010-2015

**Harshil Shah** , Guthrie Robert Packer Hosp, Sayre, PA; Shantanu Solanki, Guthrie Robert Packer Hosp, SAYRE, PA; Achint Patel, Univ of Arkansas for Medical Sciences, Little Rock, AR; Hee Kong Fong, Univ of Missouri - Columbia, Columbia, MO; Edo None Kaluski, Robert Packer Hosp, Sayre, PA

3:00 PM

Board # 3093

Regional Variation in Procedural and Clinical Outcomes Among Patients With ST Elevation Myocardial Infarction With Cardiogenic Shock

**Alejandro Lemor** , Mir Babar Basir, Tarun Jain, Pedro A Villablanca, Michele Voeltz, Khaldoon Alaswad, William O'Neill, Henry Ford Hosp, Detroit, MI

# Abstract Poster Session

## CE.APS.05 - Exosomes

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 1124

Femalecompared to Male MSC-Derived Exosomes: Females'Are Superior for Promotingipsc Differentiation and Proliferation

**Amarylis Bonito Wanschel** , Alessandro Salerno, Konstantinos Hatzistergos, Wendou Yu, Ivonne Hernandez Schulman, Wayne Balkan, Joshua M Hare, Univ of Miami, Miami, FL

3:00 PM

Board # 1125

Exosomal MicroRNAs Regulate Myofibroblast Activation in Myocardial Infarction

Xujun Wang, Einstein Coll of Med, New York, NY; Christopher Chavez, AECOM, Bronx, NY; Celestino Sardu, Vanvitelli Univ, Naples, Italy; **Gaetano Santulli** , Einstein Coll - Montefiore Univ Hosp, New York, NY

3:00 PM

Board # 1126

AAVs Meet Exosomes: Exosomal AAVs for Shielding Neutralizing Antibodies and Improved Cardiac Gene Delivery in vivo

**Marta Adamiak** , Morad Asadi, Yaxuan Liang, Divya Jha, Lauren Wills, Prabhu Mathiyalagan, Neha Agarwal, Erik Kohlbrenner, Icahn Sch of Med at Mount Sinai, New York, NY; Dongtak Jeong, Mount Sinai Medical Ctr, New York, NY; Delaine K Ceholski, Mount Sinai Sch of Med, New York, NY; Nicole Dubois, Icahn Sch of Med at Mount Sinai, New York, NY; Roger Joseph Hajjar, Mount Sinai Cardiovascular Res, New York, NY; Susmita Sahoo, Mount Sinai Sch of Med, New York, NY

3:00 PM

Board # 1127

Exosomes Secreted by Cardiosphere-Derived Cells Induce an Arginase 1-Dependent Phenotype in Diverse Macrophage Polarization States That Promotes Angiogenesis

**Kyle I Mentkowski** , Asma Mursleen, Jonathan D Snitzer, Jennifer K Lang, Univ at Buffalo, Buffalo, NY

3:00 PM

Board # 1128

Surface Modification Of Stem Cell Exosomes Myocardial Infarction Specific Peptides For Non Invasive Delivery To Ischemic Myocardium

**Vandana Mallaredy** , Zhongjian Cheng, Venkata Garikipati, Maria Cimini, Grace Huang, Chunlin Wang, Temple Univ, Philadelphia, PA; May Trungcao, Temple Univ, Paoli, PA; Cindy Benedict, Temple Univ, Philadelphia, PA; Raj Kishore, Temple Univ Sch of Med, Philadelphia, PA

3:00 PM

Board # 1129

Exosomes Derived From Podoplanin Positive Cells Lead Fibrosis and Inflammation in Healthy Mouse Heart

**Maria Cimini** , Venkata Garikipati, Chunlin Wang, May Truongcao, Grace Huang, Vandana Mallaredy, Temple Univ,Lewis Katz Sch, Philadelphia, PA; Cindy Benedict, Temple Univ, Philadelphia, PA; Raj Kishore, Temple Univ Sch of Med, Philadelphia, PA

3:00 PM

Poster Professor

Jennifer L Strande, Milwaukee, WI

# Abstract Poster Session

## HF.APS.28 - Factors Influencing Outcome in Heart Failure

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2347

Differences in Self-Care and Symptoms Do Not Explain the Higher Frequency of Hospitalization in Heart Failure Patients Who Lives in a Food Desert

**Tracy Shirey** , Emory Univ Sch Med, Atlanta, GA; Ruowen Qi, Emory Univ Sch of Public Health, Atlanta, GA; Aditi Nayak, Eisha Udeshi, Emory Univ Sch Med, Atlanta, GA; Shivani Patel, Emory Univ Sch of Public Health, Atlanta, GA; Javed Butler, Emory, Atlanta, GA; Arshed A Quyyumi, Emory Univ, Atlanta, GA; Alanna A Morris, Emory Univ Sch Med, Atlanta, GA

3:00 PM

Board # 2348

Factors Associated With Ejection Fraction Improvement Among Hospitalized Heart Failure Patients With Reduced Ejection Fraction

Atushi Suzuki, **Erina Tomari** , Tsuyoshi Shiga, Msayuki Sakai, Akihiro Osada, Noriko Kikuchi, Nobuhisa Hagiwara, Tokyo Women's Medical Univ, Tokyo, Japan

3:00 PM

Board # 2349

Exploring the Implications of Pain Symptoms in Patients With Heart Failure

**Kent Y Feng** , Duke Univ Medical Ctr, Durham, NC; Christopher M Oconnor, Inova Heart & Vascular Inst, Arlington, VA; Robert Clare, Duke Clinical Res Inst, Durham, NC; Brooke Alhanti, Duke Univ, Durham, NC; Ileana L Pina, Detroit Medical Ctr Heart Hosp, Detroit, MI; William E Kraus, Duke Univ Medical Ctr, Durham, NC; David J Whellan, Jefferson Heart Inst, Philadelphia, PA; Robert J Mentz, Duke Clinical Res Inst, Durham, NC

3:00 PM

Board # 2350

Etiologies and Predictors of 30-Day Readmission in Hospitalized Patients With Heart Failure Complicated by Cardiogenic Shock in the United States

**Zekun Feng** , UCLA Medical Ctr, Los Angeles, CA; Boback Ziaeian, UCLA, Los Angeles, CA

3:00 PM

Board # 2351

Contemporary Quality of Life and Outcomes in Patients With Heart Failure With Reduced Ejection Fraction and Comorbid Diabetes Mellitus in the CHAMP-HF Registry

**Muthiah Vaduganathan** , Brigham and Women's Hosp, Boston, MA; Javed Butler, Univ of Mississippi, Jackson, MS; Adam David Devore Sr., Duke Clinical Res Inst, Durham, NC; Puza P. Sharma, Novartis Pharmaceutical Corp, East Hanover, NJ; Stephen J Greene, Duke Univ Medical Ctr, Durham, NC; Nancy M Albert, Cleveland Clinic, Chesterland, OH; Carol I Duffy, Novartis Pharmaceuticals Corp, East Hanover, NJ; Larry HILL, Duke Clinical Res Inst, Durham, NC; J Herbert H Patterson, Univ of North Carolina, Chapel Hill, NC; John Spertus, Mid America Heart Inst, Kansas City, MO; Laine E Thomas, Duke Univ, Durham, NC; Fredonia B Williams, Mended Hearts, Huntsville, AL; Adrian F Hernandez, Duke Univ Sch of Med, Durham, NC; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA

3:00 PM

Board # 2352

Predictors of Perceived Dyspnea Burden in Heart Failure

**Kenneth M Faulkner** , Boston Coll Stony Brook Univ, Rocky Point, NY; Corrine Y Jurgens, Boston Coll, Centerville, MA; Karen Lyons, Boston Coll, Chestnut Hill, MA; Christopher S Lee, Boston Coll William F. Connell Sch of Nursing, Chestnut Hill, MA

3:00 PM

Board # 2353

Levosimendan Restores Microcirculatory Impairment Following Cardiac Arrest

**Linda Bingener** , Priyanka Böttger, Roland Wimmer, Henning Lemm, Michael Buerke, St Marien Hosp, Siegen, Germany

3:00 PM

Board # 2354

Real-World Outcomes Among Patients Hospitalized for De Novo versus Worsening Chronic Heart Failure With Reduced Ejection Fraction in the United States

**Taylor S Triana** , Duke Univ Sch of Med, Durham, NC; Raluca Lonescu-Ittu, Analysis Group, Inc., Montréal, QC, Canada; Rebecca Burne, Annie Guerin, Analysis Group, Inc., Montreal, QC, Canada; Maria Borentain, Paul Kessler, Aylin Tugcu, Mary DeSouza, Bristol Myers Squibb, Lawrenceville, NJ; Stephen J Greene, Duke Univ Sch of Med, Durham, NC; G. Michael Felker, Duke Univ Sch of Med, Please Select, NC; Lei Chen, Bristol Myers Squibb, Lawrenceville, NJ

3:00 PM

Board # 2355

Prognostic Significance of Peripheral Artery Disease in Heart Failure With Preserved Left Ventricular Ejection Fraction

**Koichiro Fujisue** , Takanori Tokitsu, Kumamoto Univ, Kumamoto, Japan; Eiichiro Yamamoto, Kumamoto Univ Hosp, Kumamoto, Japan; Daisuke Sueta, Kumamoto Univ Grad Schl Med Sci, Kumamoto, Japan; Masafumi Takae, Taiki Nishihara, Kumamoto Univ Hosp, Kumamoto, Japan; Fumi Oike, Kumamoto Univ Hosp, Kumamoto city, Japan; Takashi Komorita, Kumamoto Univ, Kumamoto, Japan; Hiroki Usuku, Kumamoto Univ Hosp, Kumamoto city, Japan; Yuichiro Arima, Seiji Takashio, Kenji Sakamoto, Koichi Kaikita, Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

3:00 PM

Board # 2356

Readmission-Free Period and In-Hospital Mortality at the Time of First Readmission in Acute Heart Failure Patients

**Ahmed M Altibi** , Harvard T.H. Chan Sch of Public Health, Harvard Univ, Boston, MA; George Prousi, Lehigh Valley Health Network, Allentown, PA; Mahek Shah, Montefiore Medical Ctr, The Bronx, NY; Manyoo Agarwal, UTHSC-Memphis, Memphis, TN; Pradhum Ram, Albert Einstein Medical Ctr, Philadelphia, PA; Byomesh K Tripathi, Mount Sinai St. Luke's-Mount Sinai West Hosp, New York, NY; Shantanu Patil, SSM Health, St Mary's Hosp, Saint Luke, MO; Brijesh D Patel, Henry Ford Allegiance Health, Jackson, MI

3:00 PM

Poster Professor

Larry A Allen, Aurora, CO

# Abstract Poster Session

## CE.APS.06 - Fibrosis

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 1131

Cardioselective Galectin-3 Overexpression in Mice Activates MAPK/ERK1/2 Signaling and Induces Myocardial Fibrosis

**Swati D Sonkawade** , Gen Suzuki, Shirley Xu, Univ at Buffalo, Buffalo, NY; Kristi Kc, Roswell Park Comprehensive Cancer Ctr, Buffalo, NY; Saraswati Pokharel, Roswell Park Cancer Inst, Buffalo, NY; Umesh C Sharma, Univ at Buffalo, Buffalo, NY

3:00 PM

Board # 1133

Vascular Endothelial Growth Factor Enhances Profibrotic Activities Through Modulation of Calcium Homeostasis in Human Atrial Fibroblasts

**Cheng Chih Chung** , Yung-Kuo Lin, Taipei Medical Univ, Taipei City, Taiwan; Yao-Chang Chen, Natl Defense Medical Ctr, Taipei City, Taiwan; Yu Kao, TingI Lee, Yi-Jen Chen, Taipei Medical Univ, Taipei City, Taiwan

3:00 PM

Board # 1134

EZH2 as a Novel Therapeutic Target for Atrial Fibrosis and Atrial Fibrillation

**Shuai Song** , Qunshan Wang, Xinhua Hosp Affiliated to Shanghai Jiaotong Univ Sch of Med, Shanghai, China

3:00 PM

Board # 1135

Myofibroblast-Derived Exosomes Induce Endothelial Dysfunction

Prabhat Ranjan, Rajesh Kumari, Jing Li, Univ of Alabama at Birmingham, Birmingham, AL; Raj Kishore, Temple Univ Sch of Med, Philadelphia, PA; **Suresh K Verma** , Univ of Alabama at Birmingham, Birmingham, AL

3:00 PM

Board # 1136

**Downregulation of Gene** p63 **Enhances Reprogramming of Human Cardiac Fibroblasts Towards a Cardiac Fate**

**Jaya Pratap Pinnamaneni** , Vivek P Singh, Mary Kim, Ayman Almousa, Deepthi Sanagasetti, Aarthi Pugazenthi, Megumi Mathison, Kai Wang, Davis So, Abdussalam Elsenousi, Alexis Edward Shafii, Jianchang Yang, Todd K Rosengart, Baylor Coll of Med, Houston, TX

3:00 PM

Board # 1137

Effects of Protease Activated Receptor-1 Signaling Inhibition on Cardiac Hypertrophy and Fibrosis in Renin Overexpressing Hypertensive Mice

**Yoshikazu Yokono** , Masato Narita, Yousuke Kawamura, Tomo Kato, Natsumi Kudo, Michiko Tsushima, Yuichi Toyama, Kenji Hanada, Michiko Shimada, Tomohiro Osanai, Hirofumi Tomita, Hirosaki Univ Graduate Sch of Med, Hirosaki, Japan

3:00 PM

Board # 1138

Endothelial Foxp1 Regulates Cardiac Fibrosis via Endothelial-To-Mesenchymal Transition

**Jie Liu** , Shanghai East Hosp, Shanghai, China; Tao Zhuang, Shanghai East Hosp, Shanghai; Xiaoli Chen, Yashu Kuang, Yanfang Wang, Lin Zhang, Yuzhen Zhang, Shanghai East Hosp, Shanghai, China

# Abstract Poster Session

## CH.APS.14 - Fontan 2020

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 4051

Microvascular Dysfunction in Patients With Fontan Physiology

**Francis X McGowan Jr.** , Joshua J Blinder, Ariel Vincent, Ping Hu, Kathryn M Dodds, Childrens Hosp of Philadelphia, Philadelphia, PA; Matthew Jolley, Children's Hosp of Philadelphia, Philadelphia, PA; Jack Rychik, David J Goldberg, Childrens Hosp of Philadelphia, Philadelphia, PA; Andrew C Glatz, Children's Hosp of Philadelphia, Swarthmore, PA; Hans Vink, Maastricht Univ, Maastricht, Netherlands; Yoav Dori, Childrens Hosp of Philadelphia, Philadelphia, PA

3:00 PM

Board # 4052

Global Shifts in the Matabolome of Infants With Single Ventricle Heart Disease Before and After Superior Cavo-Pulmonary Anastomosis

**Benjamin S Frank** , Karlise Lewis, Children's Hosp Colorado, Aurora, CO; Ludmila Khailova, Univ of Colorado, Aurora, CO; Lori Silveira, UC Denver Anschutz Campus, Aurora, CA; Max B Mitchell, Univ of Colorado, Aurora, CO; Gareth Morgan, Univ of Colorado - Children's, Aurora, CO; Mark Twite, Children's Hosp Cardiology, Aurora, CO; Michael V Di Maria, Children's Hosp Colorado, Aurora, CO; Jelena Klawitter, Univ of Colorado AMC, Aurora, CO; Jesse Davidson, Univ of Colorado Denver, Denver, CO

3:00 PM

Board # 4053

Arginase Concentration in the Fontan Circulation is Associated With Pulmonary Artery Size and Effusion History, and Arginase Activity Predicts Lower Pulmonary Bloodflow

**Jon A Detterich** , Scott Leopold, Childrens Hosp Los Angeles, Los Angeles, CA; Payal Shah, Children's Hosp Los Angeles, Los Angeles, CA; Silvie Suriany, Children's Hosp Los Angeles, Los Angeles, CA; Honglei Liu, Childrens Hosp Los Angeles, Los Angeles, CA; Frank Harris, Roshan George, Emory Univ, Atlanta, GA; Neil Patel, Sarah Badran, Children's Hosp of Los Angeles, Los Angeles, CA; Loretta Z Reyes, Emory Univ, Atlanta, GA; John C Wood, Childrens Hosp Los Angeles, Los Angeles, CA; Lou Ann Scism Brown, Claudia R Morris, Emory Univ, Atlanta, GA

3:00 PM

Board # 4054

Serum Biochemical Biomarkers Predict Lower Cardiac Index in Adolescents and Young Adults With Fontan Circulation

**Bradley S Marino** , Ann & Robert H. Lurie Children's Hosp of Chicago, Chicago, IL; Amy Cassedy, Cincinnati Children's Hosp, Cincinnati, OH; Adam L Dorfman, Univ of Michigan, Ann Arbor, MI; Michael D Taylor, Cincinnati Children's Hosp, Cincinnati, OH; Mark Alan Fogel, Children's Hosp of Philadelphia, Philadelphia, PA; Alvin Chin, Univ of Pennsylvania, Philadelphia, PA; Caren Goldberg, Mott Children's Hosp, Ann Arbor, MI; David Goldberg, Children's Hosp of Philadelphia, Philadelphia, PA; Bryan Goldstein, Cincinnati Children's Hosp, Cincinnati, OH; David B Gremmels, Children's Heart Ctr, Minneapolis, MN; Marshall L. Jacobs, Johns Hopkins Sch of Med, Baltimore, MD; Anitha John, Children's Natl Medical Ctr, Washington, DC; Heidi Kalkwarf, Eileen King, Cincinnati Children's Hosp, Cincinnati, OH; David M Overman, Children's Heart Clinic PA, Minneapolis, MN; Christina Phelps, Nationwide Children's Hosp, Columbus, OH; Robert D Stewart, Cleveland Clinic, Cleveland, OH; Babette Zemel, Amanda Shillingford, Children's Hosp of Philadelphia, Philadelphia, PA; Lazaros Kochilas, Children's Healthcare of Atlanta, Atlanta, GA

3:00 PM

Board # 4055

Changes in Cerebral Clood Flow in Relation to Systemic to Pulmonary Collateral Flow as Fontan Patients Age: A Modifiable Risk Factor for Adverse Neurodevelopment?

**Nazire Ozcelik** , Quynh T Tran, Children's Hosp of Philadelphia, Philadelphia, PA; Alicia J Lozano, Alexandra L Hanlon, Virginia Tech, Roanoke, VA; Kazuhiro Shiraga, Children's Hosp of Philadelphia, Philadelphia, PA; Sara Partington, Children's Hosp of Philadelpia, Philadelphia, PA; Matthew A Harris, Children's Hosp of Philadelphia, Philadelphia, PA; David M Biko, Children's Hosp of Phladelphia, Philadelphia, PA; Kevin K Whitehead, Mark Alan Fogel, Children's Hosp of Philadelphia, Philadelphia, PA

3:00 PM

Board # 4056

Single Ventricles, Ventricular Morphology and Imposition of Fontan Physiology: Effects on Strain and Global Measures of Function Using Cardiac Magnetic Resonance Imaging

**Kazuhiro Shiraga** , Quynh Tran, Nazire Ozcelik, Matthew A Harris, Kevin K Whitehead, David M Biko, Sara Partington, Mark Alan Fogel, The Children's Hosp of Philadelphia, Philadelphia, PA

3:00 PM

Board # 4057

Comparison of Fontan Outcomes After Superior Cavopulmonary Connection With and Without Elimination of Antegrade Pulmonary Blood Flow

**Thomas W Dietzman** , Children's Hosp of Philadelphia, Philadelphia, PA; Stefania Soria, Albert Einstein Medical Ctr, Philadelphia, PA; John Depaolo, Univ of Pennsylvania, Philaelphia, PA; Matthew J Gillespie, Christopher Mascio, Yoav Dori, Michael L O'Byrne, Jonathan J Rome, Andrew C Glatz, Children's Hosp of Philadelphia, Philadelphia, PA

3:00 PM

Board # 4058

Impact of Protein Losing Enteropathy in Children Who Underwent the Fontan Operation: A Single Large Institution Experience

**Baneen Alkofair** , Children's Natl Health System, Washington, DC; Abdulmajeed Alruwaili, Nicklaus Children's Hosp, Miami, FL; Jiaxiang Gai, Ashraf S Harahsheh, Children's Natl Health System, Washington, DC

3:00 PM

Board # 4059

Maternal Race/Ethnicity Predicts Timing of Transfer to Destination Hospital in Neonates With Hypoplastic Left Heart Syndrome in California

**Neha J Purkey** , Lucile Packard Children's Hosp at Stanford, Palo Alto, CA; Henry Lee, Stanford Univ, Stanford, CA; Chen Ma, Susan Hintz, Lucile Packard Children's Hosp at Stanford, Palo Alto, CA; Doff B McElhinney, Stanford Univ Medical Ctr, Palo Alto, CA; Suzan Carmichael, Lucile Packard Children's Hosp at Stanford, Palo Alto, CA

3:00 PM

Board # 4060

A Meta-Analysis of Health-Related Quality of Life in Children, Adolescents and Adults With a Fontan Circulation

**Kate H Marshall** , The Sydney Children's Hosp Network, Sydney, Australia; Yves d'Udekem, Royal Childrens Hosp, Melbourne, Australia; Gary F Sholler, The Sydney Children's Hosp Network, Sydney, Australia; Alexander R Opotowsky, Brigham and Women's Hosp and Children's Hosp, Boston, MA; Daniel S J Costa, Louise Sharpe, The Univ of Sydney, Sydney, Australia; David S Celermajer, Royal Prince Alfred Hosp, Sydney, Australia; David S Winlaw, The Sydney Children's Hosp Network, Sydney, Australia; Nadine A Kasparian, Boston Children's Hosp, Boston, MA

# Abstract Poster Session

## HF.APS.24 - Heart Failure I

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2307

Left Ventricular Unloading Preserves Energy Substrate Utilization and Protects the Functional Integrity of Mitochondrial Complex I in Preclinical Models of Ischemia With and Without Reperfusion

**Lija Swain** , Xiaoying Qiao, Lara Alexis Reyelt, Aditya Chennojwala, Shreyas Bhave, Michael T Chin, Corinne Thomas, Shiva Annamalai, Paige Crowley, Tufts Medical Ctr, Boston, MA; Navin K Kapur, Tufts Medical Ctr, Hanover, MA

3:00 PM

Board # 2308

Single-beat Estimation of Preload Recruitable Stroke Work and Its Coupling to Arterial Load in the Human Left Ventricle

**Ryo Inuzuka** , Hikoro Matsui, Univ of Tokyo, Tokyo, Japan; Hideaki Senzaki, Kitasato Univ, Sagamihara, Japan

3:00 PM

Board # 2309

Microvesicles Rescue Cardiomyocytes From Doxorubicin Injury via Mitochondrial Transfer in a Patient Specific Model of Anthracycline Induced Cardiomyopathy

**Connor G Obrien** , Stanford Hosp, Stanford, CA; Mehmet O Ozen, Stanford Univ, Palo Alto, CA; Evgenia Vaskova, Stanford Hosp, Stanford, CA; Michelle Santoso, Stanford Univ, Stanford, CA; Christine Wahlquist, Stanford Univ, Palo Alto, CA; Ji Hye Jung, Stanford Sch of Med, Stanford, CA; Gentaro Ikeda, Liye Shi, Utkan Demirci, Stanford Univ, Palo Alto, CA; Mark Mercola, Phillip C Yang, Stanford Univ, Stanford, CA

3:00 PM

Board # 2310

Endothelial Hspa12b and Yap Cooperatively Promote Angiogenesis Following Myocardial Infarction

**Min Fan** , Kun Yang 37614, Yana Wang 37601, Fei Tu 37601, Tuanzhu Ha, East Tennessee State Univ, Johnson City, TN; Li Liu, First Affiliated Hosp of Nanjing Medical Univ, Nanjing; John Kalbfleisch, David L Williams 37601, Chuanfu Li, East Tennessee State Univ, Johnson City, TN

3:00 PM

Board # 2311

Induction of Cardiomyocyte Proliferation via Transient Expression of Cell Cycle Factors as a Promising Therapy for Heart Failure

**Riham Abouleisa** , Univ of Louisville, louisville, KY; Qinghui Ou, Univ of Louisville, Louisville, KY; Xian-liang Tang, Yan Li, Wenjian Wu, Heather Stowers, Nashwah Alhariry, Ahmed Elshaer, Rama Nassri, Asma Hagsharfi, Univ of Louisville, louisville, KY; Roberto Bolli, Tamer m Mohamed, Univ of Louisville, Louisville, KY

3:00 PM

Board # 2312

Pgrn Suppresses Pressure Overload-induced Cardiac Hypertrophy and Heart Failure in Mice via Inhibiting the Activation of β-catenin

**Yinghong Zhu** , Osaka Unversity, Osaka, Japan

3:00 PM

Board # 2313

Binucleation Increase in Response to Infarction Injury of Murine Ventricular Cardiomyocytes

**Kathleen M Broughton** , David Ebeid, Carolina Esquer, Bingyan Jessica Wang, Maryam Moshref, Mark Alan Sussman, San Diego State Univ, San Diego, CA

3:00 PM

Board # 2314

An Orally Available Novel Antagonist Against Corticotropin Releasing Hormone Receptor 2 Prevents Cardiac Dysfunction in Mouse Heart Failure Model

**Mikito Takefuji** , Nagoya Univ Sch of Med, Nagoya, Japan; Hyi-Man Park, Ayako Tsuchihira, Masashi Ohmi, Akiyoshi Fujiuchi, Yumi Isogai, RaQualia Pharma Inc., Nagoya, Japan; Toyoaki Murohara, Cardiology, Nagoya Univ, Nagoya, Japan

3:00 PM

Board # 2315

Cardiac Metabolism Was Improved by Regulation of Nitric Oxide Synthases Through the Beta-3 Adrenergic Receptor in Endotoxin-induced Failing Heart

Motoi Okada, **Satoshi Kawaguchi** , Asahikawa Medical Univ, Asahikawa, Japan; Satoshi Fujita, Asahikawa Medeical Univ, Asahikawa, Japan; Naoyuki Hasebe, Asahikawa Medical Univ, Asahikawa, Japan

3:00 PM

Poster Professor

Joshua M Hare, Miami, FL

3:00 PM

Board # 2316

The Role of Glycolysis-Dependent Accessory Pathways in Myocardial Recovery Upon Mechanical Unloading in Heart Failure Patients

**Rachit Badolia** , Dinesh Ramadurai, Peter Ferrin, Iosif Taleb, Thirupura S. Shankar, Aspasia Thodou, Michael Yin, Univ of Utah, Salt Lake City, UT; Stephen H McKellar, Univ of Utah, Salt Lake Cty, UT; Craig Selzman, Utah Univ, Salt Lake City, UT; Virginia B Hebl, Intermountain Medical Ctr, Murray, UT; Sutip Navankasattusas, Omar E Wever-Pinzon, Jared Rutter, Univ of Utah, Salt Lake City, UT; Stavros G Drakos, Univ of Utah, Salt Lake Cty, UT

3:00 PM

Board # 2317

Acetoacetate is Associated With Poor Prognosis in Heart Failure Patients

**Tetsuro Yokokawa** , Akiomi Yoshihisa, Yasuhiro Ichijo, Koichiro Watanabe, Yuki Kanno, Fukushima Medical Univ, Fukushima, Japan; Satoshi Abe, Hikarigaoka 1, Fukushima, Japan; Tomofumi Misaka, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

# Abstract Poster Session

## HF.APS.31 - Heart Failure Pathophysiology II

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2372

**Enhanced TNFR1 Expression Delivers Anti-Apoptotic and Proliferative Signals in CD4** + **T-Lymphocytes During Chronic Heart Failure**

Rachel Rosenzweig, Roman Covarrubias, The Ohio State Univ, Columbus, OH; Ameen Ismahil, Univ of Alabama at Birmingham, Birmingham, AL; Jessica A Robinson, Richard J Gumina, The Ohio State Univ, Columbus, OH; Sumanth D Prabhu, Univ of Alabama at Birmingham, Birmingham, AL; **Shyam S Bansal** , The Ohio State Univ, Columbus, OH

3:00 PM

Board # 2373

Downregulation of Mitophagy-regulating Proteins in Left Ventricular Myocardium of Dogs With Chronic Heart Failure

**Hani N Sabbah** , Ramesh C Gupta, Vinita Singh-Gupta, David E. Lanfear, Henry Ford Hosp, Detroit, MI

3:00 PM

Board # 2374

Abnormalities of Mitophagy in the Failing Heart Worsen in the Presence of Cardiorenal Syndrome

**Ramesh C Gupta** , Vinita Singh-Gupta, Hani N Sabbah, Henry Ford Hosp, Detroit, MI

3:00 PM

Board # 2375

Serum-induced Expression of Brain Natriuretic Peptide Contributes to Its Increase in Patients With Heart Failure

**Ryuji Okamoto** , Ryotaro Hashizume, Mie Univ Graduate Sch of Med, Tsu, Japan; Noboru Suzuki, Mie Univ Life Science Res Ctr, Tsu, Japan; Hiroshi Kiyonari, RIKEN Ctr for Life Science Technologies, Kobe, Japan; Masaaki Ito, Mie Univ Graduate Sch of Med, Tsu, Japan

3:00 PM

Board # 2376

Whole Exome Sequencing Identifies Multigenic Heterozygosity in a Multigeneration Family With History of Arrhythmogenic Dilated Cardiomyopathy, Heart Failure, Wpw Syndrome and Mitral Valve Prolapse

**Enkhsaikhan Purevjav** , Univ of Tennessee Health Science, Memphis, TN; Wenying Zhang, Uzmee Mendsaikhan, Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; Fuyi Xu, Lu Lu, Univ of Tennessee Health Science, Memphis, TN; Jeffrey A Towbin, Le Bonheur Childresn Hosp, Memphis, TN

3:00 PM

Board # 2377

Are Patients With Type 2 Diabetes Mellitus Protected From Takotsubo Cardiomyopathy?

**Nazli Kubra Okumus** , Meera Kondapaneni, MetroHealth Medical Ctr, Cleveland, OH

3:00 PM

Board # 2378

Role of Thyroid in Takotsubo Cardiomyopathy: A Multicenter Retrospective Observational Study

**Anandbir Singh Bath** , Western Michigan Univ Homer Stryker MD Sch of Med, Kalamazoo, MI; Chetaj Mahabir, Univ of Nebraska Medical Ctr, Omaha, NE; Sourabh Aggarwal, Ascension Borgess Medical Ctr, Kalamazoo, MI; Lalit Wadhwani, Univ of Nebraska Medical Ctr, Omaha, NE; Jacob Morton, Alysa Hernandez, Western Michigan Univ Homer Stryker MD Sch of Med, Kalamazoo, MI; Gregory S Pavlides, Univ of Nebraska Medical Ctr, Omaha, NE; Vishal Gupta, Jagadeesh K. Kalavakunta, Ascension Borgess Medical Ctr, Kalamazoo, MI

3:00 PM

Board # 2379

Dilated Cardiomyopathy Includes Arrhythmogenic Cardiomyopathy as a Type With Severe Myocardial Degeneration

Kosuke Mozawa, **Tsunenori Saito** , Eiichiro Oka, Nippon Medical Sch, Tokyo, Japan; Naoko Saito-Sato, Japanese Red Cross Medical Ctr, Tokyo, Japan; Eitaro Kodani, Nippon Medical Sch Tama-Nagayama Hosp, Tokyo, Japan; Yu-ki Iwasaki, Nippon Medical Sch, Tokyo, Japan; Kuniya Asai, Nippon Medical Sch Chiba Hokusoh Hosp, Chiba, Japan; Wataru Shimizu, Nippon Medical Sch, Tokyo, Japan

3:00 PM

Board # 2380

Sex Differences in Adiposity and Future Heart Failure With Preserved Ejection Fraction Risk

**Satyam Sarma** , Univ Texas Southwestern Medical Ctr, Dallas, TX; Erin Howden, Baker Heart and Diabetes Inst, Melbourne, Australia; William K Cornwell II, Univ of Colorado Anschutz Med, Aurora, CO; Justin S Lawley, Univ of Innsbruck, Innsbruck, Austria; Sheryl A Livingston, Inst for Exercise and Environmental Med, Dallas, TX; Mitchel Samels, IEEM, Dallas, TX; Braden Everding, Texas Health Dallas, Dallas, TX; Dean Palmer, Univ Texas Southwestern Medical Ctr, Dallas, TX; Benjamin D Levine, UT Southwestern Medical Ctr, Dallas, TX

3:00 PM

Board # 2381

Increase in Myocardial Glucose Uptake in the Dilated Cardiomyopathy Associated With Reduction of Left Ventricular Ejection Fraction

**Atsushi Tobiume** , Kagawa Univ, Kagawa, Japan; Takahisa Noma, Kagawa Univ, Kita, Kagawa, Japan; Ishikawa Shouhei, Kagawa Univ, Kagawa, Japan; Keiji Matsunaga, Kagawa Univ, Japan, Kagawa, Japan; Ryo Kawakami, Kagawa Univ, Kita-gun Miki-cho, Japan; Yuichi Miyake, Kagawa Univ, Kagawa, Japan; Makoto Ishizawa, Kagawa Univ, Kagawa Prefecture, Japan; Ishikawa Kaori, Genki Kurashita, Takuma Sakamoto, Teppei tsuji, Murakami Kazushi, Kagawa Univ, Kagawa, Japan; Tetsuo Minamino, Dept of Cardiorenal and Cerebrovascular Med, Faculty of Med, Kagawa Univ, Kita-gun, Japan

3:00 PM

Poster Professor

Prateeti Khazanie, Denver, CO

# Abstract Poster Session

## EA.APS.22 - ICD Management Issues

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2156

A Survey of Antibiotic Use During Insertion of Cardiovascular Implantable Devices Amongst US Implanters

Hung Vo, RWJ Rutgers Medical Sch, New Brunswick, NJ; Dayna Scott, Medtronic Corp, Moundsview, MN; James Coromilas, **John Kassotis** , RWJ Rutgers Medical Sch, New Brunswick, NJ

3:00 PM

Board # 2157

A Multicenter, Real-time, in-vitro Observation of Transient Malfunctions in Contemporary Wireless-enabled Pacemakers and Implantable Cardioverter-defibrillators During Radiotherapy Courses up to 10 Gy

**Enrico Di Girolamo** , Arrhythmology Unit, SS. Annunziata Hosp, Chieti, Italy; Nanda Furia, Arrhythmology Unit, "SS. Annunziata" Hosp, Chieti, Italy; Marianna Appignani, Intensive Cardiac Care Unit, "SS. Annunziata" Hosp, Chieti, Italy; Massimiliano Marini, Cardiology Unit, "S. Chiara" Hosp, Trento, Italy; Paolo De Filippo, Cristina Leidi, Electrophysiology Unit, ASST Papa Giovanni XXIII, Bergamo, Italy; Anna Delana, Medical Physics Unit, "S. Chiara" Hosp, Trento, Italy; Agnese Barbareschi, Medical Physics Unit, Tor Vergata Univ, Rome, Italy; Stefano Andreoli, Medical Physics Unit, ASST Papa Giovanni XXIII, Bergamo, Italy; Domenico Genovesi, Maria Daniela Falco, Radiotherapy Unit, "SS. Annunziata" Hosp, Chieti, Italy

3:00 PM

Board # 2158

Outcomes of Prospective ICD Reprogramming to Reduce Risk of Unnecessary ICD Therapy

**Matthew Martini** , Univ of Wisconsin Hosp, Madison, WI; Matthew Kalscheur, Miguel Angelo Leal, Univ of Wisconsin, Madison, WI; Erin Dehn, Teri McSherry, William S Middleton Memorial VA Hosp, Madison, WI; Timothy Hess, Univ of Wisconsin Hosp and Clinics, Madison, WI; Ryan T Kipp, Univ of Wisconsin Hosp, Madison, WI

3:00 PM

Board # 2159

Novel ICD Programming on Inappropriate ICD Therapy in Patients With Very Low Ejection Fraction: A MADIT-RIT Sub-Study

**Anas Jawaid** , Univ of Rochester Medical Ctr, Rochester, NY; Moulin Chokshi, Massachusetts General Hosp, Boston, MA; Wojciech Zareba, Univ of Rochester Medical Ctr, Rochester, NY; Claudio D Schuger, Henry Ford Hosp, Detroit, MI; James Patrick Daubert, Duke Univ Med Ctr, Durham, NC; Scott McNitt, Univ of Rochester Medical Ctr, Rochester, NY; Jagmeet P Singh, Massachusetts General Hosp, Boston, MA; Ilan Goldenberg, Valentina Kutyifa, Univ of Rochester Medical Ctr, Rochester, NY

3:00 PM

Board # 2160

Safety of Recent Cardiac Implantable Devices During Oncologic Radiotherapy: A Prospective, Multicenter, Randomized, in-vitro Study

**Enrico Di Girolamo** , Arrhythmology Unit, SS. Annunziata Hosp, Chieti, Italy; Massimiliano Marini, Cardiology Unit, "S. Chiara" Hosp, Trento, Italy; Paolo De Filippo, Electrophysiology Unit, ASST Papa Giovanni XXIII, Bergamo, Italy; Massimiliano Faustino, Arrhythmology Unit, "SS. Annunziata" Hosp, Chieti, Italy; Marianna Appignani, Intensive Cardiac Care Unit, "SS. Annunziata" Hosp, Chieti, Italy; Cristina Leidi, Electrophysiology Unit, ASST Papa Giovanni XXIII, Bergamo, Italy; Domenico Genovesi, Radiotherapy Unit, "SS. Annunziata" Hosp, Chieti, Italy; Stefano Andreolia, Medical Physics Unit, ASST Papa Giovanni XXIII, Bergamo, Italy; Anna Delana, Medical Physics Unit, "S. Chiara" Hosp, Trento, Italy; Agnese Barbareschi, Medical Physics Unit, Tor Vergata Univ, Rome, Italy; Maria Daniela Falco, Radiotherapy Unit, "SS. Annunziata" Hosp, Chieti, Italy

3:00 PM

Board # 2161

Treatment Modalities for the Prevention of Implantable Cardioverter Defibrillator Shocks: Systematic Review and Network Meta-Analysis

**Leonardo M Knijnik** , Michael W Kaplan, Jackson Memorial Hosp - Univ of Miami, Miami, FL; Manuel Rivera, Gilson Fernandes, Univ of Miami, Miami, FL; Rhanderson Cardoso, Johns Hopkins Univ, Baltimore, MD; Amanda Fernandes, Litsa K Lambrakos, Raul Mitrani, Jeffrey J Goldberger, Univ of Miami, Miami, FL

3:00 PM

Board # 2162

Timing is Everything: Time to Entrainment Using Antitachycardia Pacing Predicts Successful Termination of Ventricular Tachycardia in Patients With Implantable Defibrillator Cardioverters

**Ryan G Aleong** , Univ Colorado, Aurora, CO; Michael Rosenberg, Blake Fleeman, Univ of Colorado, Aurora, CO

3:00 PM

Board # 2163

Short- And Long-Term Change in Lead Impedance in the Subcutaneous Implantable Cardioverter-Defibrillator

**Willeke van der Stuijt** , Anne-Floor B.E. Quast, Sarah W.E. Baalman, Koen C. de Wilde, Arthur M Wilde, Reinoud Knops, Amsterdam UMC, location AMC, Amsterdam, Netherlands

3:00 PM

Board # 2164

Characteristics and Outcomes of Patients With Spontaneous Coronary Artery Dissection Who Suffered Sudden Cardiac Arrest

**Derek Phan** , Kaiser Permanente Los Angeles Medical Ctr, Los Angeles, CA; Ryan Clare, Kaiser Permanente, Los Angeles, CA; Cheng Chen, Rikin Tank, Ming-Sum Lee, Kaiser Permanente Los Angeles Medical Ctr, Los Angeles, CA

# Abstract Poster Session

## CE.APS.04 - Immune Cells

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Poster Professor

Sujith Dassanayaka, Louisville, KY

3:00 PM

Board # 1113

Increased Right Ventricular Macrophages and NLRP3 in Monocrotaline Pulmonary Hypertension

**Ruaa Al-Qazazi** , Patricia D.A. Lima, Francois Potus, Lian Tian, Monica Neuber-Hess, Jeffrey Mewburn, Stephen L Archer, Queen's Univ, Kingston, ON, Canada

3:00 PM

Board # 1114

Beneficial Bacteria Enhance Cardiovascular Health by Modulating Inflammation and Nrf2 Pathway Signaling

**Crystal Naudin** , Joshua Owens, Liping Luo, Rheinallt Jones, Emory Univ, Atlanta, GA

3:00 PM

Board # 1115

Macrophage β2-Adrenergic Receptor Influences Angiogenesis Through Paracrine-Dependent Mechanisms

Toby Thomas, Miles Tanner, **Laurel Grisanti** , Univ of Missouri, Columbia, MO

3:00 PM

Board # 1116

Clec4e-Signalling Influences the Recruitment of Leukocytes Towards the Infarct Area Following Myocardial Ischemia-Reperfusion Injury

**Denise Veltman** , Hilde Gillijns, Ellen Caluwé, Ming Wu, Maarten Vanhaverbeke, Katholieke Univ Leuven, Leuven, Belgium; Peter R Sinnaeve, UZ Leuven, Leuven, Belgium; Stefan Pierre Janssens, Univ Hosp Gasthuisberg, Leuven, Belgium

3:00 PM

Board # 1117

Prediminance of Th1 and Th17 During Myocardial Infarction in Sr-bi Ko/apoer61h/h Mice

**Hiroyasu Inui** , Makoto Nishida, Jo Kyuyou, Zhu Yinghong, Kanno Kotaro, Takeshi Okada, Ohama Toru, Masahiro Koseki, Sakata Yasushi, Osaka Univ Graduate Sch of Med, Suita Osaka, Japan; Shizuya Yamashita, Rinku General Medical Ctr, Izumisano Osaka, Japan

3:00 PM

Board # 1118

Mononucleated and Binucleated Ventricular Myocytes Have Distinct Transcriptomes and Stress Responses

Jining Yang, Xuewei Xia, The Third Military Medical Univ, Chongqing, China; Guo Yu, Xiaoyan Wu, The Third MIlitary Medical Univ, Chongqing, China; Ao Shen, Xiaoying Zhang, Bin Xu, Bin Xu, Univ of California at Davis, Davis, CA; Miyuraj Harishchandra Hikkaduwa Withanage, Universtiy of Iowa, Iowa City, IA; Min Zhou, The Third Military Medical Univ, Chongqing, China; Jie Liu, Shenzhen Univ Sch of Med, Shenzhen, China; Wei Wang, The Third Military Medical Univ, Chongqing, China; Erliang Zeng, Univ of Iowa, Iowa City, IA; Ying Tian, Temple Univ, Philadelphia, PA; Weizhong Zhu, Nantong Univ, Nantong City, China; Steven R Houser, Immediate Past President- AHA, Philadelphia, PA; Yang K Xiang, Univ California, Davis, CA; Chunyu Zeng, Mantian Mi, The Third Military Medical Univ, Chongqing, China; **Xiongwen Chen** , Temple Univ, Philadelphia, PA

3:00 PM

Board # 1120

Myeloid Cell-Specific Epidermal Growth Factor Receptor Regulates the Immune Response in the Infarcted Heart

**Ama Dedo Okyere** , Sara Sar, Joshua Strong, Erin McEachern, Rhonda Carter, Erhe Gao, Douglas Tilley, Temple Univ, Philadelphia, PA

3:00 PM

Board # 1121

Reparative Macrophages Contribute to Development of Solid Replacement Fibrosis Through Protecting Cardiac Fibroblasts

**Manabu Shiraishi** , Atsushi Yamaguchi, Jichi Medical Univ, Saitama Medical Ctr, Saitama-city, Japan; Ken Suzuki, Queen Mary Univ of London, London

3:00 PM

Board # 1122

VEGFR1 Regulates Fatty Acid Metabolism to Modulate Ischemic Macrophage Polarization in Peripheral Artery Disease

**Vijay C Ganta** , Vascular Biology Ctr, Augusta, GA

3:00 PM

Board # 1123

MiR-200c-5p Regulates Epithelial-to-Mesenchymal Transition in Epicardial Mesothelial Cells by Targeting Epicardial Follistatin-Related Protein 1

Elena Pontemezzo, Eleonora Foglio, Enza Vernucci, Sapienza Univ of Rome, Rome, Italy; Marco D'agostino, Istituto Dermopatico dell'Immacolate, IDI-IRCCS, Rome, Rome, Italy; Alessandra Magenta, Istituto Dermopatico Immacolata, Rome, Italy; Astanina Elena, Univ of Turin, Candiolo and Candiolo Cancer Inst-FPO-IRCCS, Turin, Italy; Federico Bussolino, Univ of Turin, Candiolo and Candiolo Cancer Inst-FPO-IRCCS, Torino, Italy; Matteo Russo, IRCCS San Raffaele Pisana and MEBIC Consortium, San Raffaele Open Univ, Rome, Rome, Italy; **Federica Limana** , San Raffaele Open Univ, Rome and IRCCS San Raffaele Pisana, Rome, Rome, Italy

# Abstract Poster Session

## SA.APS.10 - Late Breaking Science in Valve and Thoracic Aortic Surgery

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 4303

Immediate Impact of Aortic Valve Replacement on Descending Aortic Circumferential Strain in Aortic Stenosis and Aortic Insufficiency

**Lisa Rong** , Weill Cornell Med, New York, NY; Maria Chiara Palumbo, Weill Cornell Medical Coll, New York, NY; Samantha Huynh, Richard B Devereux, Mario Gaudino, Weill Cornell Med, New York, NY; Jonathan W Weinsaft, Weill Cornell Medical Coll, Scarsdale, NY

3:00 PM

Board # 4304

Prognostic Impact of Sarcopenia Measured by Preoperative Computerized Tomography Scan in Older Patients Undergoing Surgical Aortic Valve Replacement

**Seung-Ah Lee** , Il-Young Jang, Sahmin Lee, Kyung Won Kim, Ho Jin Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Eunju Lee, Jong-Min Song, Cheol-Hyun Chung, Duk-Hyun Kang, Jae-Kawn Song, Jae-Won Lee, Dae-Hee Kim, Asan Medical Ctr, Seoul, Korea, Republic of

3:00 PM

Board # 4305

Residual Mitral Regurgitation After Aortic Valve Replacement in Patients With Severe Aortic Stenosis: Echocardiographic Predictors and Impact on Long-Term Survival

**Emile Voisine** , IUCPQ, Québec, QC, Canada; Pierre Voisine, IUCPQ, Quebec, QC, Canada; Frédéric Beaupré, Mohamed Marzouk, Mario Sénéchal, IUCPQ, Québec, QC, Canada

3:00 PM

Board # 4306

Neo-Chord Construction on Fusion Cusp for Bicupid Aortic Valve Repair in Combination With Aortic Root Repair

**Kikuko Obase** , Takashi Miura, Junichiro Eishi, Hiroko Taguchi, Taku Inoue, Akihiko Tanigawa, Tessho Kitamura, Shun Nakaji, Ichiro Matsumaru, Kiyoyuki Eishi, Nagasaki Univ Hosp, Nagasaki, Japan

3:00 PM

Board # 4309

Proximal Aortic Disease in Women - A Matter of Estrogen Receptors?

**Josephina Haunschild** , Heart Ctr Leipzig, Leipzig, Germany; Sarah Barnard, Saxonian Incubator for Clinical Translation, Leipzig, Germany; Piroze M Davierwala, Heart Ctr Univ Leipzig, Leipzig; Michael Andrew Borger, Leipzig Heart Ctr, Leipzig, Germany; Christian D Etz, Heart Ctr Leipzig, Leipzig

3:00 PM

Board # 4310

Discordant Associations Between Atherosclerotic Risk Factors and the Risk of Ascending Thoracic Aortic Aneurysm

**Makoto Mori** , Sameh Yousef, Haoran Zhuo, Syed Usman Bin Mahmood, Hamid Mojibian, Yale Sch of Med, New Haven, CT; Yawei Zhang, Yale Sch of Public Health, New Haven, CT; Arnar Geirsson, Yale Univ, New Haven, CT

3:00 PM

Board # 4311

**mIR-376c is Decreased in Marfan Syndrome and Results in Increased Smad4/TGF-beta Signaling** in vitro

**Elizabeth N Robertson** , Stefanie Suzanne Portelli, Renjing Liu, Brett D Hambly, Richmond W Jeremy, Univ of Sydney, Sydney, Australia

# Abstract Poster Session

## EP.APS.17 - LDL, Statins and Cardiovascular Disease Prevention

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 3094

Automated Electronic Health Record Screening for Familial Hypercholesterolemia

**Kristen Bede** , Peter Bazeley, Erin McMullen, Kelsey Girbino, Cleveland Clinic, Cleveland, OH; Nishant P Shah, Cleveland Clinic, Cleveland Heights, OH; Leslie Cho, Cleveland Clinic Fndn, Cleveland, OH; Wai Hong Wilson Tang, Cleveland Clinic, Cleveland, OH

3:00 PM

Board # 3095

Prevalence and Control of Primary Severe Hypercholesterolemia in Olmsted County, Minnesota: A Community-Based Study

**Medhat Farwati** , Mayo Clinic, Rochester, MN; Magdi Zordok, Carney Hosp, Boston, MA; Ashwini Bhat, Mayo Clinic, Rochester, MN; Maya Safarova, Saint Barnabas Medical Ctr, Livingston, NJ; Kent Bailey, Tina Wood-Wentz, Carin Smith, Iftikhar J Kullo, Mayo Clinic, Rochester, MN

3:00 PM

Board # 3096

Use of Guideline-Recommended Risk-Reduction Strategies Among Patients With Prior MI: Insights From Getting to an Improved Understanding of Low-Density Lipoprotein Cholesterol and Dyslipidemia Management (GOULD)

**Suzanne V Arnold** , Saint Luke's Mid America Heart Inst and Univ of Missouri-Kansas City, Kansas City, MO; James A De Lemos, UT Southwestern Medical Ctr, Dallas, TX; Robert S Rosenson, Mt Sinai Sch of Med, New York, NY; Christie M Ballantyne, Baylor Coll of Med, Houston, TX; Yuyin Liu, Baim Inst for Clinical Res, Boston, MA; Katie Mues, Shushama Alam, Mary Elliott-Davey, Amgen, Thousand Oaks, CA; Deepak L Bhatt, Christopher Paul Cannon, Brigham and Women's Hosp, Boston, MA; Mikhail N Kosiborod, Saint Luke's Mid America Heart Inst and Univ of Missouri-Kansas City, Kansas City, MO

3:00 PM

Board # 3097

Safety of High Intensity Statin in Asian Patients With Acute Myocardial Infarction

**Po-Sheng Chen** , Yi-Heng Li, Hui-Wen Lin, Sheng-Hsiang Lin, Natl Cheng Kung Univ Hosp, Tainan City, Taiwan

3:00 PM

Board # 3098

Prevalence of Statin Non-adherence Determined by Therapeutic Drug Monitoring (TDM) in Patients With Uncontrolled Hypertension

**Bryan Wu** , Shishir Sharma, Hamza Lodhi, Kevin Schesing, Sandeep R Das, Univ of Texas Southwestern, Dallas, TX; Nancy Brown, Vanderbilt Univ Medical Ctr, Nashville, TN; Elizabeth Moss, Ethan A Halm, Wanpen Vongpatanasin, Univ of Texas Southwestern, Dallas, TX

3:00 PM

Board # 3099

Does the Intensity of Lipid Lowering Therapy Vary by Sex in the United States? Insights From Getting to an Improved Understanding of Low-Density Lipoprotein Cholesterol and Dyslipidemia Management (GOULD): A Registry of High Cardiovascular Risk Patients in the United States

**Daniel Yazdi** , Brigham and Women's Hosp, Boston, MA; Christopher Paul Cannon, Brigham and Women's Hosp, Boston, MA; James A De Lemos, UT Southwestern Medical Ctr, Dallas, TX; Christie M Ballantyne, Baylor Coll of Med, Houston, TX; Robert S Rosenson, MT Sinai Sch of Med, New York, NY; Katie Mues, Shushama Alam, Mary Elliott-Davey, Amgen, Thousand Oaks, CA; Yuyin Liu, Baim Inst for Clinical Res, Boston, MA; Deepak L Bhatt, Brigham and Women's Hosp, Boston, MA; Mikhail N Kosiborod, Saint Luke's Mid America Heart Inst and Univ of Missouri-Kansas City, Kansas City, MO

3:00 PM

Board # 3100

Efficacy of Bempedoic Acid: A Pooled Analysis of 4 Pivotal Phase 3 Clinical Trials

**Maciej Banach** , Medical Univ of Łódź and Polish Mother's Memorial Hosp Res Inst, Łódź, Poland; P. Barton Duell, Oregon Health Sciences Univ, Portland, OR; Antonio Gotto, Weill Cornell Medical Coll, New York, NY; Ulrich Laufs, Leipzig Univ, Leipzig, Germany; Lawrence A Leiter, St. Michael's Hosp, Univ of Toronto, Toronto, ON, Canada; G. B. John Mancini, Univ of British Columbia, Vancouver, BC, Canada; Kausik K Ray, Imperial Coll London, London, United Kingdom; JoAnn Flaim, Zhan Ye, Esperion Therapeutics, Inc., Ann Arbor, MI; Alberico L Catapano, Univ of Milan and IRCCS Multimedica, Milan, Italy

3:00 PM

Board # 3101

Assessing Low-Density Lipoprotein Cholesterol Risk in Secondary Prevention Patients Within The PINNACLE National Outpatient Registry

Joseph Mark Allen, American Coll of Cardiology, Washington, DC; Suzanne V Arnold, Saint Luke's Cardiovascular Consultants, Kansas City, MO; Nicole L Lohr, Medical Coll of Wisconsin, Wauwatosa, WI; Lonny Reisman, HealthReveal, New York, NY; Ameen F Ghannam, Sanofi, Bridgewater, NJ; Santosh K Sanganalmath, Regeneron Pharmaceuticals, Inc., Tarrytown, NY; Irfan Khan, Sanofi, Bridgewater, NJ; Serban Iorga, Regeneron Pharmaceuticals, Inc., Tarrytown, NY; **Dharam Kumbhani** , Southwestern Medical Ctr, Dallas, TX

3:00 PM

Board # 3103

Utility of Pre-Treatment Non-Cholesterol Sterols in the Prediction of LDL-C Lowering Response to Statins and Ezetimibe

Paul T Williams, Michael L Dansinger, Boston Heart Diagnostics, Framingham, MA; H. Robert Superko, Heart Disease Inst, Carmel, CA; **Ernst J Schaefer** , Boston Heart Diagnostics, Framingham, MA

# Abstract Poster Session

## HF.APS.27 - Management Strategies in CHF

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2337

The Impact of Management in a Heart Failure Center Within a Primary Care Clinic on Clinical Outcome in Patients With Chronic Heart Failure

**Elisha J Ouzan** , Hadassah Hebrew Medical Ctr, Jerusalem, Israel

3:00 PM

Board # 2338

Beta Blockers After HFrEF Hospitalization Decrease Short Term Mortality Across the Age Spectrum

**Lauren Gray Gilstrap** , Dartmouth Hitchcock Medical Ctr, Lebanon, NH; Andrea M Austin, The Dartmouth Inst, Lebanon, NH; Barbara Gladders, Dartmouth Hitchcock Medical Ctr, Lebanon, NH; James O'Malley, Amber Barnato, Anna Tosteson, Jonathan Skinner, The Dartmouth Inst, Lebanon, NH

3:00 PM

Board # 2339

Impact of Thoracentesis on the Outcome of Acute Congestive Heart Failure for In-hospitalized Patients in the United States

**Suchith Shetty** , Univ of Iowa, Iowa City, IA; Aaqib Malik, Westchester Medical Ctr, Valhall, NY; Wilbert S Aronow, New York Medical Coll, New Rochelle, NY; Alexandros Briasoulis, Paulino Alvarez, Univ of Iowa, Iowa City, IA

3:00 PM

Board # 2340

Effect of a Quality Improvement Intervention for Acute Heart Failure in India: An Interrupted Time Series Study

**Anubha Agarwal** , Northwestern Univ, Chicago, IL; Padinhare P Mohanan, Westfort Hi-Tech Hosp, Thrissur, India; Dimple Kondal, Ctr for Chronic Disease Control, New Delhi, India; Divin Davies, Westfort Hi-Tech Hosp, Thrissur, India; Raji Devarajan, Ctr for Chronic Disease Control, New Delhi, India; Govindan Unni, Jubilee Mission Medical Coll and Hosp, Thrissur, India; Jabir Abdullakutty, Lisie Hosp, Ernakulum, India; Syam Natesan, Kollam District Hosp, Kollam, India; Johny Joseph, Caritas Hosp, Thellakom, India; Pathiyil B. Jayagopal, Lakshmi Hosp, Palakkad, India; Stigi Joseph, Little Flower Hosp and Res Ctr, Angamaly, India; Rajesh Gopinath, Amala Inst of Medical Sciences, Thrissur, India; Mark D Huffman, Northwestern Univ, Chicago, IL; Dorairaj Prabhakaran, Ctr for Chronic Disease Control, New Delhi, India

3:00 PM

Board # 2341

Inpatient Heart Failure Initiative With Home Health Outpatient Collaboration Reduces Heart Failure Readmissions

**Tarun Sharma** , Aaron Gopal, Medical Coll of Georgia, Augusta, GA; Deborah Crew, Augusta Univ Medical Ctr, North Augusta, SC; Stephanie Dunlap, Medical Coll of Georgia, Augusta, GA

3:00 PM

Board # 2342

Clinical Usage and Outcomes of Wearable Cardioverter-Defibrillators: Experience of a Large Integrated Academic Health System

**Jadry Gruen** , Alexander Thomas, Peter A Kahn, Nihar R. Desai, Yale Sch of Med, New Haven, CT

3:00 PM

Board # 2343

Impact of Intensive Guideline-Directed Medical Therapy for Ischemic Heart Failure Outcomes

**Rebecca Crosier** , Cassandra Freitas, Heather J Ross, Univ Health Network, Toronto, ON, Canada; Patrick R Lawler, Peter Munk Cardiac Ctr, Toronto, ON, Canada; Peter C Austin, Dennis T Ko, Therese A Stukel, ICES, Toronto, ON, Canada; Michael E Farkouh, Peter Munk Cardiac Ctr, Toronto, ON, Canada; Xuesong Wang, ICES, Toronto, ON, Canada; John A Spertus, Mid America Heart Inst, Kansas City, MO; Douglas S Lee, ICES, Toronto, ON, Canada

3:00 PM

Board # 2344

IMPACT OF EVIDENCE-BASED EMR POINT-OF-CARE ALERTS IN GUIDING MEDICAL THERAPY IN PATIENTS WITH CONGESTIVE HEART FAILURE

Zahra Azizi, Southlake Regional Helath Ctr, Aurora, ON, Canada; Hadi Tohidi, Southlake Regional Helath Ctr, Newmarket, ON, Canada; Pouria Alipour, Southlake Regional Health Ctr, Newmarket, ON, Canada; Amirhossein Sharifzad, Southlake Regional Health Ctr, Richmond hill, ON, Canada; **Yaariv Khaykin** , Southlake Regional Health Ctr, Newmarket, ON, Canada

3:00 PM

Board # 2345

Point of Care Lung Ultrasound Predicts Heart Failure Readmissions

**David Fridman** , Allison Cohen, Glenford Robinson, Mathew Nelson, Timmy Li, Simon Maybaum, Gerin R Stevens, Northwell Health, Manhasset, NY

3:00 PM

Board # 2346

Hybrid Telerehabilitation and Telecare is More Efffective Than Usual Care in Improving Peak Vo2 and 6-Minute Walk Distance but is Not Associated With Reduction of 24-Months Mortality Except in the Most Experienced Center - Result of the First Randomized, Prospective, Open-Label, Parallel Group, Controlled, Multi-Center - Telereh-Hf Study

Ewa Piotrowicz, Ryszard Piotrowicz, Inst of Cardiology, Warsaw, Poland; Grzegorz Opolski, Medical Univ of Warsaw, Warsaw, Poland; Piotr Orzechowski, Inst of Cardiology, Warsaw, Poland; Slawomir Pluta, Silesian Ctr for Heart Diseases, Zabrze, Poland; Renata Glowczynska, Medical Univ of Warsaw, Warsaw, Poland; Dominika Szalewska, Medical Univ of Gdansk, Gdansk, Poland; Robert Irzmanski, Medical Univ of Lodz, Lodz, Poland; Michael Pencina, Duke Univ's Sch of Med, Durham, SC; Ilona Kowalik, Inst of Cardiology, Warsaw, Poland; Tomasz Krauze, Poznan Univ of Medical Sciences, Poznan, Poland; Anna Mierzynska, Inst of Cardiology,, Warsaw, Poland; Maciej Banach, Medical Univ of Lodz, Lodz, Poland; **Wojciech Zareba** , Univ of Rochester Medical Ctr, Rochester, NY

3:00 PM

Poster Professor

Eldrin F Lewis, Boston, MA

# Abstract Poster Session

## EA.APS.20 - Mechanisms and Therapeutic Approaches to Ventricular Arrhythmias

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2133

Short PVC Coupling Interval Predicts LV Dysfunction in a Swine Model of Ectopy Mediated Cardiomyopathy

**Adam Chee-Hey Lee** , UCSF, San Francisco, CA; Tomos E Walters, Univ of California San Francisco, San Francisco, CA; Christina Alhede, UCSF Medical Ctr, San Francisco, CA; Emily Wilson, Rich Sievers, UCSF, San Francisco, CA; Edward Gerstenfeld, UCSF, SanFrancisco, CA

3:00 PM

Board # 2134

Pairing Improved Maturation With Metabolic Stress Reveals Disease-Like Features in Tissue Models of Arrhythmogenic Cardiomyopathy

**Justin Lowenthal** , Adriana Blazeski, Robert Hawthorne, Roald Teuben, Deborah DiSilvestre, Johns Hopkins Univ Sch of Med, Baltimore, MD; Gordon F Tomaselli, Albert Einstein Coll of Med, Bronx, NY; Kenneth Boheler, Johns Hopkins Univ Sch of Med, Baltimore, MD; Sharon Gerecht, Johns Hopkins Univ, Baltimore, MD; Leslie Tung, Johns Hopkins Univ Sch of Med, Baltimore, MD

3:00 PM

Board # 2135

Inhibition of Tgfβ Signaling Rescues Wavering Ventricular Pacing Induced by TBX18 Gene Transfer in the Ambulatory Rat Model of Complete Atrioventricular Block

**Nam Kyun Kim** , Natasha Fernandez, Emory Univ, Atlanta, GA; David Wolfson, Hee Cheol Cho, Emory Univ and Georgia Inst of Technology, Atlanta, GA

3:00 PM

Board # 2136

A High-Throughput Phenotype-Based Subtype Classification of Long-QT Syndrome Using Induced Pluripotent Stem Cell Model

**Daisuke Yoshinaga** , Shiro Baba, Takeru Makiyama, Hirofumi Shibata, Takuya Hirata, Hirohiko Kohjitani, Yimin Wuriyanghai, Yuta Yamamoto, Kyoto Univ, Kyoto, Japan; Bruce Conklin, Gladstone, San Franscisco, CA; Minoru Horie, Shiga Univ of Medical Science, Otsu, Japan; Junko Takita, Toshio Heike, Kyoto Univ, Kyoto, Japan

3:00 PM

Board # 2137

A Common Genetic Variant of the Cardiac Sodium Channel Predisposes to Drug-induced QT Prolongation

**Yuko Wada** , Laura L Daniel, Cristian M Shaffer, Andrew M Glazer, Kevin R Bersell, Marcia A Blair, Lynn Hall, Laura L Short, Tao Yang, Dan M Roden, Vanderbilt Univ Medical Ctr, Nashville, TN

3:00 PM

Board # 2138

Acetylcholine Activates Small-conductance Calcium-activated Potassium Current to Induce J-wave Elevation in Rabbit Hearts

**Yudong Fei** , Krannert Inst of Cardiology, Indiana Univ Sch of Med, Indianapolis, IN; Mu Chen, Indiana Univ, Indianapolis, IN; Shuai Guo, Krannert Inst of Cardiology, Indiana Univ Sch of Med, Indianapolis, IN; Zhenhui Chen, Michael Rubart, Indiana Univ, Indianapolis, IN; Thomas Everett, Krannert Inst of Cardiology, Indianapolis, IN; Zhilin Qu, UCLA, Los Angeles, CA; James N Weiss, David Geffen Sch of Med UCLA, Los Angeles, CA; Peng-Sheng Chen, Krannert Inst of Cardiology, Indianapolis, IN

3:00 PM

Board # 2139

**Sex-specific** IKas **Activation in Rabbit Ventricles With Drug-induced Qt Prolongation**

**Adonis Z Wu** , Mu Chen, Shuai Guo, Dechun Yin, Zhenhui Chen, Indiana Univ Sch of Med, Indianapolis, IN; James N Weiss, Zhilin Qu, UCLA, Los Angeles, CA; Thomas Everett IV, Peng-Sheng Chen, Indiana Univ Sch of Med, Indianapolis, IN

3:00 PM

Board # 2140

Electronic Cigarette Aerosols Induce Arrhythmogenic Changes in Cardiac Conduction in Mice Partly via Autonomic Pathways

**Alex Perrow Carll** , Renata Salatini, Claudia Arab, Aruni Bhatnagar, Daniel J Conklin, Univ of Louisville, Louisville, KY

3:00 PM

Board # 2141

Recapitulating the Long QT Syndrome Phenotype in IPSC-Derived Cardiomyocytes

**Ning Ge** , Regenerative Med Inst, Galway, Ireland; Min Liu, Hebei Normal Univ, Shijiazhuang, China; Janusz Krawczyk, Galway Univ Hosp, Galway, Ireland; Veronica McInerney, Natl Univ of Ireland, Galway, Ireland; Joseph Galvin, Mater Misericordiae Univ Hosp, Dublin, Ireland; Sanbing Shen, Timothy O'Brien, Regenerative Med Inst, Galway, Ireland; Terence William Prendiville, Children's Health Ireland, Dublin, Ireland

3:00 PM

Board # 2142

**Mitochondrial Ca** 2+ **Flux Contributes to Arrhythmia During Acute Ischemia**

**An Xie** , Hong Liu, Feng Feng, Gyeoung-Jin Kang, Univ of Minnesota, Minneapolis, MN; Bum-Rak Choi, Tae Yun Kim, CVRC RIH and Brown Medical Sch, Providence, RI; Samuel C Dudley, Univ of Minnesota, Minneapolis, MN

# Abstract Poster Session

## EP.APS.18 - Methodologic Advancements in CV Research

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 3104

Dynamic Prediction of Cardiovascular Disease Risk Accounting for Future Statin Treatment Effect

**Zhe Xu** , Matthew Arnold, David Stevens, Angela M Wood, Univ of Cambridge, Cambridge, United Kingdom

3:00 PM

Board # 3105

Electrocardiographic Criteria for Silent Myocardial Infarction: Impact of Different Definitions on Detection Rates and Prognostic Significance in the Atherosclerosis Risk in Communities Study

**Richard Brandon Stacey** , Wake Forest Univ Sch of Med, Winston Salem, NC; Ronald J Prineas, Ronald J Prineas, New York, NY; Zhu-ming Zhang, Wake Forest Sch of Med, Winston Salem, NC; Bruce Psaty, Univ of Washington, Seattle, WA; Wayne D Rosamond, Univ NC Sch Public Hlth, Chapel Hill, NC; Lynne Wagenknecht, Wake Forest Univ Sch of Med, Winston Salem, NC; Elsayed Z Soliman, Wake Forest Sch of Med, Winston Salem, NC

3:00 PM

Board # 3107

Increasing Engagement in the Electronic Framingham Heart Study (eFHS): A Factorial Randomized Trial

**Ludovic Trinquart** , Boston Univ Sch of Public Health, Boston, MA; David D McManus, Univ of Massachusetts Medical Sch, Worcester, MA; Christopher Nowak, Care Evolution, Ann Arbor, MI; Vik Kheterpal, CareEvolution, Ann Arbor, MI; Emily S Manders, Kelsey Fusco, Framingham Heart Study, Framingham, MA; Honghuang Lin, Nicole L Spartano, Boston Univ, Boston, MA; Chunyu Liu, Boston Univ Sch of Public Health, Boston, MA; Belinda Borrelli, Boston Univ Henry M. Goldman Sch of Dental Med, Boston, MA; Emelia J Benjamin, Boston Univ Sch Med, Brookline, MA; Joanne Murabito, Boston Univ Sch of Med, Framingham, MA

3:00 PM

Board # 3108

Laboratory-based Intermountain Risk Score Compared to The Charlson and Elixhauser Comorbidity Indices for Mortality Prediction

**Benjamin D Horne** , Intermountain Medical Ctr and Univ of Utah, Salt Lake City, UT; Gregory L Snow, Allison Butler, Emily L Wilson, Intermountain Healthcare, Salt Lake City, UT; Susan Rea, Sarah Majercik, Intermountain Medical Ctr, Salt Lake City, UT; Jeffrey L Anderson, Intermountain Medical Ctr and Univ of Utah, Salt Lake City, UT; Joseph Bledsoe, Intermountain Medical Ctr and Stanford Univ, Salt Lake City, UT

3:00 PM

Board # 3110

Data Loss in Registered Cardiovascular and Cerebrovascular Clinical Trials

**Alexander Zheutlin** , Eric Stulberg, Univ of Utah, Salt Lake City, UT; Joshua Niforatos, Johns Hopkins Univ, Baltimore, MD; Jeremy B Sussman, Univ of Michigan, Ann Arbor, MI

3:00 PM

Board # 3111

Artificial Intelligence Based Clinical Risk Assessment in Predicting Cardiac Related Chest Pain in Patients Presenting to Emergency Room

Keattiyoat Wattanakit, **Harshavardhan Ghadiam** , Sudhir Mungee, OSF Medical Ctr, Peoria, IL; Mohammad Imtiaz, Bradley Univ, Peoria, IL

3:00 PM

Board # 3112

Expecting the Unexpected Beyond Borders:Apple Watch as a Global Screening Tool for Dysrhythmia in the Developing World

**Swaiman Singh** , Alexis K Okoh, Newark Beth Israel Medical Ctr, Newark, NJ; Vijay Pratap Singh, The Wright Ctr for Graduate Medical Education, Scranton, PA; Rohit Chowdhury, Walsall Coll, Walsall England, Walshall, United Kingdom; Affan Farooq, Newark Beth Israel Medical Ctr, Newark, NJ; Rajmeet Mann, Norton Community Hosp, Norton, VA; Adarshjit Singh, Univ of South Carolina Sch of Med, SC; Amandeep Bains Singh, Baba Jaswant Singh Dental Coll Hosp & Res Inst, Newark, NJ; Amandeep Singh, RWJ Barnabas Health NBIMC, Newark, NJ; Pawan Prasher, Sri Guru Ram Das Inst of Medical Sciences & Res, Newark, NJ; Prabhpal Hundal Singh, MBBS-Sri Guru Ram Das Inst of Medical Sciences & Res, Amritsar, India; Jatinder Singh, MBBS-Government Medical Coll, Amritsar, India; Sartaj Singh, Government Medical Coll, Amritsar, Punjab, India; Manpreet Kaur, Sri Guru Ram Das Inst of Medical Sciences & Res, Punjab, India; Ravneet Kaur, Mai Bhago Coll of Nursing, India; Sarvjit Singh, MBBS, D.Ortho - Gill Hosp, Kapurthala, India; Nicole Maguire, FACEP Emergency Med- Newark Beth Israel Medical Ctr, Newark, NJ; Najam Wasty, Newark Beth Israel Medical Ctr, India

3:00 PM

Poster Professor

Randi E Foraker, St Louis, MO

# Abstract Poster Session

## CE.APS.07 - Mitochondria

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 1139

Regulation of Mitochondrial Calcium Uniporter by MICU1

**Vivek Garg** , Ishan Paranjpe, Tiffany Unsulangi, Junji Suzuki, Univ of California, San Francisco, CA; Lorin S. Milescu, Univ of Maryland, College Park, MD; Yuriy Kirichok, Univ of California, San Francisco, CA

3:00 PM

Board # 1140

Genetically Engineered SR-Mitochondria Linker in the Mouse Heart

**Zuzana Nichtova** , Yuexing Yuan, Thomas Jefferson Univ, Philadelphia, PA; Sergio De La Fuente, Philadelphia, PA; Stephen Hurst, Celia Fernandez-Sanz, Sebastian Lanvermann, Thomas Jefferson Univ, Philadelphia, PA; Gerald W Dorn, Washington Univ, St Louis, MO; Shey-shing Sheu, Sidney Kimmel Medical Coll, Philadelhia, PA; Gyorgy Csordas, Thomas Jefferson Univ, Philadelphia, PA

3:00 PM

Board # 1142

Calsequestrin 2 and Phospholamban Gene Expression Are Associated With Increased Mitochondrial Gene Expression

**Julie H Rennison** , Sojin Y Wass, Erik Offerman, Jeff Hsu, Han Sun, Marc Gillinov, Cleveland Clinic, Cleveland, OH; Christine S Moravec, Cleveland Clinic Fndn, Cleveland, OH; Jonathan Smith, John Barnard, Mina K Chung, David R Van Wagoner, Cleveland Clinic, Cleveland, OH

3:00 PM

Board # 1143

Acute and Transient Overstretch Destructed Inner Mitochondrial Membrane Without Subsequent Cardiac Dysfunction in Rat Hearts

**Naritomo Nishioka** , Hiroki Bochimoto, The Jikei Univ Sch of Med, Tokyo, Japan; Ping Yu Xiong, Queen's Univ, Kingston, ON, Canada; Shunsuke Baba, Jun Tanihata, Susumu Minamisawa, Yoichiro Kusakari, The Jikei Univ Sch of Med, Tokyo, Japan

3:00 PM

Board # 1144

Mitochondrial Membrane Potential Oscillations Persist During Reperfusion After Ischemia in MCU-KO Myocytes

**Deepthi Ashok** , Kyriakos Papanicolaou, Ting Liu, Brian O'Rourke, Johns Hopkins Univ, Baltimore, MD

3:00 PM

Board # 1145

Linoleic Acid Improves Assembly of the Complex II Subunit and Complex III/IV Complex of the Mitochondrial Oxidative Phosphorylation System in Heart Failure

**Satoshi Maekawa** , Otaru-kyokai hospital, Otaru, Japan; Shingo Takada, Hokusho Univ, Ebetsu, Japan; Hideo Nambu, Hokkaido Social Work Association Obihiro Hosp, Obihiro, Japan; Takaaki Furihata, Stanford Sch of Med, Stanford, CA; Hisataka Sabe, Shintaro Kinugawa, Hokkaido Univ, Sapporo, Japan

3:00 PM

Board # 1146

Identification of Novel Micu1 Functions Independent of the Mitochondrial Calcium Uniporter

**Dhanendra Tomar** , Joanne Garbincius, Devin Kolmetzky, Manfred Thomas, Pooja Jadiya, John W Elrod, Temple Univ, Philadelphia, PA

3:00 PM

Board # 1147

The Impact of The Mitochondria Transfers From Mesenchymal Stem Cell to Cardiomyocytes on Functional Recovery in the Distressed Myocardium

**Daisuke Mori** , Shigeru Miyagawa, Takuji Kawamura, Hiroki Hata, Takayoshi Ueno, Koichi Toda, Kotoe Kawai, Hayato Kurata, Hiroyuki Nishida, Yoshiki Sawa, Osaka Univ, Suita, Japan

3:00 PM

Board # 1148

Deficiency of Bone Morphogenetic Protein-3b Increases the Activity of the C/ebpα Promoter and Adipogenesis

**Ingrid Marti-Pamies** , Univ of Pennsylvania, Philadelphia, PA; Robrecht Thoonen, Massachusetts General Hosp, Boston, MA; Alexia Vite, Alex Caplan, Jesus Tamez, Wei Han, Univ of Pennsylvania, Philadelphia, PA; Emmanuel S Buys, Ironwood Pharmaceuticals, Cambridge, MA; Donald Bloch, Massachusetts General Hosp Res Inst, Boston, MA; Marielle Scherrer-Crosbie, Univ of Pennsylvania, Philadelphia, PA

# Abstract Poster Session

## SA.APS.11 - Myocardial Protection, Intraoperative Management and Critical Care II

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 4313

Pivotal Role of Chitinase-3-like Protein 1, a Novel Myokine in Exercise Training-Induced Protection Against Cardiomyocyte Apoptosis and Promotion of Angiogenesis After Myocardial Infarction in Rats

Zhenjun Tian, Zhuo Li, Shaanxi Normal Univ, Xi'an, China; **Lei XI** , Virginia Commonwealth Univ, Richmond, VA

3:00 PM

Board # 4314

Interleukin-18 in Contributes to the Reperfusion Injury in Donation After Circulatory Death Heart

**Stefano Toldo** , Virginia Commonwealth Univ, Glen Allen, VA; Kristine Kenning, Virginia Commonwealth Univ, Richmond, VA; Eleonora Mezzaroma, Virginia Commonwealth Univ, Henrico, VA; Mohammed Quader, VCU, Richmond, VA

3:00 PM

Board # 4315

Rage Mediates On-Pump-Cabg Induced Lv Stunning

**Markus Velten** , Univ Bonn Medical Ctr, Bonn, Germany; Lynette K Rogers, Ohio State Univ, Columbus, OH; Oliver Dewald, Univ Clinical Ctr Bonn, Bonn, Germany; Rainer Meyer, Dept of Physiology, Bonn, Germany; Andreas Hoeft, Dept of Anesthesiology, Bonn; Daniel Duerr, Klinik und Poliklinik fr Herzchirurgie, Universit, Bonn

3:00 PM

Board # 4316

An Enhanced Recovery Protocol (ERP) For All Cardiac Surgeries Reduces Postoperative Length Of Stay (postopLOS) And Perhaps The Incidence Of New Onset Postoperative Atrial Fibrillation

**Jonathan Parmet** , Satoshi Furukowa, Pietro Colonna-Romano, Pennsylvania Hosp, Philadelphia, PA

3:00 PM

Board # 4317

Impact of Preoperative Risk on the Association Between Hypotension and Mortality After Cardiac Surgery

**Sophie De Roock** , Univ of Ottawa Heart Inst, Ottawa, ON, Canada; Thierry G Mesana, Ottawa Heart Inst, Ottawa, ON, Canada; Louise Sun, Univ of Ottawa Heart Inst, Ottawa, ON, Canada

3:00 PM

Board # 4318

Clinical Outcomes of Transcatheter Aortic Valve Replacement Under Conscious Sedation for Patients Concomitant With Pulmonary Hypertension

Satoru Osaki, Giorgio Gimelli, Amish N Raval, Kurt M Jacobson, Matthew R Wolff, **Kosuke Ujihira** , Univ of Wisconsin, Madison, WI

3:00 PM

Board # 4319

Implication of Potassium Inward Rectifying (Kir1.1) Channel Component in Cardioprotective Mechanism of Adenosine Triphosphate-Sensitive Potassium Channel Opener Diazoxide

**Jie Wang** , Alejandro Suarez - Pierre, Johns Hopkins Univ, Baltimore, MD; Jie Dong, Univ, Beijing; Jennifer S Lawton, Johns Hopkins Univ, Baltimore, MD

3:00 PM

Board # 4320

Acute Normovolemic Hemodilution Enhances Platelet Function Recovery Following Cardiopulmonary Bypass

Eric Sarin, Kevin Bliden, Scott D Barnett, Patricia Saulino, Inova Heart and Vascular Inst, Falls Church, VA; Udaya Tantry, Sinai Hosp of Baltimore, Baltimore, MD; Ankit vyas, Inova Heart and Vascular Inst, Falls Church, VA; Alan McBain Speir, Inova Health System/CVTSA, Falls Church, VA; **Paul A Gurbel** , Inova Heart and Vascular Inst, Falls Church, VA

3:00 PM

Board # 4321

Gender Difference in Short and Long Term Outcomes in Acute Type a Aortic Dissection Repair

Elizabeth Norton, Karen Kim, Shinichi Fukuhara, Xiaoting Wu, Univ of Michigan, Ann Arbor, MI; Himanshu J Patel, Univ Michigan Health System, Ann Arbor, MI; G. Michael Deeb, **Bo Yang** , Univ of Michigan, Ann Arbor, MI

3:00 PM

Board # 4322

Frailty Evaluation Using Machine Learning Modeling for Preoperative Walking Ability in Cardiac Patients

**Hirotada Masuda** , Hidetsugu Asanoi, Osaka Univ, Suita Osaka, Japan; Shigeru Miyagawa, Osaka Univ, Suita, Japan; Kenta Masada, Osaka Univ Graduate Sch of Med, Suita Osaka, Japan; Ai Kawamura, Osaka Univ, Suita-city, Osaka, Japan; Takuji Kawamura, Osaka Univ, Osaka, Japan; Koichi Maeda, Osaka Univ Graduate Sch of Med, Osaka, Japan; Satoshi Kainuma, Osaka Univ, Suita, Japan; Daisuke Yoshioka, Osaka Univ, Suita,Osaka, Japan; Keiwa Kin, Osaka Univ Graduate Sch of Med, Kobe, Japan; Kazuo Shimamura, Osaka Univ, Osaka, Japan; Hiroki Hata, Osaka Univ Graduate Sch of, Osaka, Japan; Yasushi Yoshikawa, Osaka Univ, Suita Osaka, Japan; Takayoshi Ueno, Osaka Univ Graduate Sch of Med, Suita, Japan; Koichi Toda, Natl Cardiovascular Ctr, Kobe, Japan; Toru Kuratani, Osaka Univ / CV Surgery, Osaka, Japan; Yoshiki Sawa, Osaka Univ Graduate Sch of Med, suita, Japan

3:00 PM

Poster Professor

Amanda A. Fox, Dallas, TX

# Abstract Poster Session

## IN.APS.13 - New Frontiers in Catheter-Based Therapies

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 4203

A Combination of Malnutrition and Muscle Weakness Deteriorates Clinical Outcomes After Transcatheter Aortic Valve Replacement

**Yasuhiro Uchida** , Yokkaichi Municipal Hosp, Yokkaichi, Japan; Hideki Ishii, Nagoya Univ, Nagoya, Japan; Jun Yonekawa, Akinori Satake, Yuichiro Makino, Wataru Suzuki, Yokkaichi Municipal Hosp, Yokkaichi, Japan; Masanari Kurobe, Yokkaichi Municipal Hosp, yokkaichi, Japan; Koji Mizutani, Yoshiaki Mizutani, Hitoshi Ichimiya, Akinori Tamenishi, Junji Watanabe, Yokkaichi Municipal Hosp, Yokkaichi, Japan; Masaaki Kanashiro, Yokkaichi municipal hospital, Yokkaichi, Japan; Tetsuya Amano, Aichi Medical Univ, Nagakute, Japan; Matusbara Tatsuaki, Sch of Dentistry Aichi Gakuin Univ, Nagoya, Japan; Satoshi Ichimiya, Yokkaichi Municipal Hosp, Yokkaichi, Japan; Toyoaki Murohara, Cardiology, Nagoya Univ, Nagoya, Japan

3:00 PM

Board # 4204

Outcomes of Ultrasound-accelerated Catheter-directed Thrombolytic Therapy Versus Intravenous Thrombolysis in Pulmonary Embolism Patients---Insights From Nationwide Inpatient Sample

**Tiantian Shi** , Yale New Haven Health, Bridgeport, CT; John-Ross Clarke, Bridgeport Hosp, Bridgeport, CT; Roy Tony, Yale New Haven Health, Bridgeport Hosp, Bridgeport, CT; Amarnath Annapureddy, Yale Univ, Derby, CT; Stuart W Zarich, Bridgeport Hosp, Bridgeport, CT

3:00 PM

Board # 4205

Temporal Trends and Outcomes of Transcatheter Mitral Valve Repair and Surgical Mitral Valve Interventions

**Ayman Elbadawi** , Univ of Texas Medical Branch, Galveston, TX; Islam Y Elgendy, Ahmed Mohamed, Massachusetts General Hosp, Boston, MA; Mohamed Faher Almahmoud, Univ of Texas Medical Branch, Galveston, TX; Mohamed A Omer, 4401 Wornall Rd, Kansas City, MO; Ahmed Sami Abuzaid Jr., Jefferson/ Christiana Health Care system, Newark, DE; Ali E Denktas, Baylor Coll of Med, Houston, TX; David Paniagua, VA Medical Ctr, Houston, TX; Subhash Banerjee, VA Medical Ctr, Houston, TX, Dallas, TX; Hani Jneid, Baylor Coll Med, Houston, TX

3:00 PM

Board # 4206

High Preoperative Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios Are Associated With Higher Mortality Following Transcatheter Aortic Valve Insertion

**David Jin** , St Vincent's Hosp Melbourne, Melbourne, Australia; Arul Baradi, St Vincent's Hosp, Melbourne, Australia; Rohan Navani, St Vincent's Health, Melbourne, Melbourne, Australia; Sarah Brazel, Robert Whitbourn, St Vincent's Hosp Melbourne, Melbourne, Australia; Arthur Nasis, Monash Health, Melbourne, Australia; Andrew M Wilson, St Vincent's Hosp, Fitzroy, Australia; Sonny Palmer, St Vincent's Hosp Melbourne, Melbourne, Australia

3:00 PM

Board # 4207

Racial Disparities in Patients Undergoing Transcatheter Aortic Valve Replacement

Motaz M Baibars, Johs Hopkins Med - HCGH, Columbia, MD; **Yasser Al-Khadra** , Cleveland Clinic Fndn, Cleveland, OH; Fahed Darmoch, Beth Israel Deaconess Medical, Somerville, MA; Homam Moussa Pacha, Univ of Texas Health Science Ctr, McGovern Medical Sch, Memorial Hermann Heart & Vascular Inst, Arlington, VA; Mohamad Soud, MedStar Washington Hosp Ctr, Washington, DC; M Chadi M Alraies, Wayne State Univ - DMC, Detroit, MI

3:00 PM

Board # 4208

Long Telomere Length in Circulating Leukocytes is Associated With Monocytosis and Poorer Survival in Patients With Transcatheter Aortic Valve Replacement

**Jedrzej Hoffmann** , Univ Hosp Frankfurt, Frankfurt, Germany; Noriaki Tabata, Univ Hosp Bonn, Bonn, Germany; Silvia Mas-Peiro, Univ Hosp Frankfurt, Frankfurt, Germany; Ioakim Spyridopoulos, Newcastle Univ, Newcastle Upon Tyne, United Kingdom; Graziella Pergola, Marie-Isabel Murray, Univ Hosp Frankfurt, Frankfurt, Germany; Jan-malte Sinning, Univ Hosp Bonn, Bonn, Germany; Stefanie Dimmeler, Inst of Cardiovasular Regeneration, Frankfurt Am Main, Germany; Andreas M Zeiher, Klinikum d. J. W Goethe-Univ, Frankfurt Am Main; Mariuca Vasa-Nicotera, Univ Hosp Frankfurt, Frankfurt, Germany

3:00 PM

Board # 4209

Impact of Atrial Fibrillation on 1-year Mortality in Transcatheter Repair of Severe Functional Mitral Regurgitation

**Rakushumimarika Harada** , Texas Health Presbyterian Hosp, Dallas, TX; Michinari Hieda, UT Southwestern Medical Ctr, Dallas, TX; Yogamaya Mantha, Texas Health Presbyterian Hosp, Dallas, TX; Mayumi Fukuda-Doi, Natl Cerebral and Cardiovascular Ctr, Osaka, Japan; Jorge Cheirif, Mark Feldman, Texas Health Presbyterian Hosp, Dallas, TX

3:00 PM

Board # 4210

Anticoagulation in Patients With Atrial Fibrillation After a Transcatheter Aortic Valve Replacement: A Systematic Review

**Jason Galo** , Fahad Al Halban, Univ of Miami/Jackson Memorial Hosp, Miami, FL; Sharde Chambers, Univ of Miami/Jackson Memorial Hosp, Hollywood, FL; Eduardo de Marchena, Univ of Miami/Jackson Memorial Hosp, Miami, FL; Garly Rushler Saint Croix, Jackson Memorial Hosp, Miami, FL; Brett Milford, Univ of Miami/Jackson Memorial Hosp, Miami, FL; Odunayo Olorunfemi, Rochester General Hosp, Rochester, NY

3:00 PM

Board # 4211

Aortic Valve Replacement in Patients With End Stage Renal Disease

**Konstantinos V. Voudris** , Clifford J Kavinsky, Rush Univ Medical Ctr, Chicago, IL

# Abstract Poster Session

## AC.APS.05 - New Twists in Diagnosis & Risk Assessment in ACS

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Poster Professor

Allan S Jaffe, Rochester, MN

3:00 PM

Board # 4012

Augmenting the Efficiency of ECG Interpretation With Artificial Intelligence

**Sameer Mehta** , Edgardo Escobar, Francisco Fernandez, Sebastian Niklitschek, Carlos Villagran, Felipe Vera, Roberto Rocuant, Jorge Avila, German Cardenas, Alejandra Frauenfelder, Daniel Vieira, Gladys Pinto, Lorena Pisana, Jorge Mazzini, Rodrigo Safie, Anibal Munguia, Estefania Cecilio, Isabella Vallenilla, Carlos Peña, Jose S Aguilar, Genesis Del Nogal, Daniela Bou Daher, Pedro Cruz, Jorge Cardenas, Benjamin Wood, Akhil Vaid, Lumen Fndn, Miami, FL

3:00 PM

Board # 4013

Addressing ST Elevation Myocardial Infarction (STEMI) False Positives in Racial Subpopulations Due to Current ECG Criteria

**Muhammad Soofi** , Wright State Univ, Dayton, OH; Victor F Froelicher, Stanford Univ, Stanford, CA

3:00 PM

Board # 4014

Comparing Emergency Department Risk Stratification Tools for Chest Pain in African Americans

**Olusayo Fadiran** , Howard Univ Hosp, Washington, DC; Vishnu Priya Mallipeddi, Howard Univ Hosp, WASHINGTON, DC; Emmanuel Mbey, Henry Janna, Howard Univ Hosp, Washington, DC; Adebayo Atanda, George Washington Univ, Washington, DC; Sumon Mahbubur, Howard Univ Hosp, Washington, DC; Julius Ngwa, Howard Univ, Washington, DC; Daniel A Larbi, Howard Univ Hosp, Washington, DC

3:00 PM

Board # 4015

Limitations of ECG Criteria as Predictors of Culprit Coronary Artery in Acute Inferior Wall ST Elevation Myocardial Infarctions

**Lefan He** , Rutgers Robert Wood Johnson, New Brunswick, NJ; Miles Shen, Rutgers New Jersey Medical Sch, Newark, NJ; Bobby D Ghosh, New York Presbyterian Hosp, New York, NY; Ashok Chaudhary, Rutgers Robert Wood Johnson, New Brunswick, NJ; Brian Anyanwu, Rutgers Robert Wood Johnson, Piscataway, NJ; Kelly Gao, John Kassotis, Rutgers Robert Wood Johnson, New Brunswick, NJ; James Coromilas, Rutgers Robert Wood Johnson, Ridgewood, NJ

3:00 PM

Board # 4016

Prospective Validation of the 2015 Esc 0-Hour/1-Hour Algorithm Using High-Sensitivity Cardiac Troponin T in Asian Countries

**Masayuki Shiozaki** , Kenji Inoue, Juntendo Univ Nerima Hosp, Tokyo, Japan; Satoru Suwa, Juntendo Univ Shizuoka Hosp, Izunokuni, Japan; Lee Chien-Chang, Natl Taiwan Univ Hosp, Taipei, Taiwan; Chiang Shuo-Ju, Taipei City Hosp, Taipei, Taiwan; Hiroshi Tamura, Yasumasa Fujiwara, Masataka Sumiyoshi, Juntendo Univ Nerima Hosp, Tokyo, Japan

3:00 PM

Board # 4017

Kinetics of High-Sensitivity Cardiac Troponin I and T Following Symptom Onset in Non-ST-Segment Elevation Myocardial Infarction: It is Time to Revise the Textbooks

Yader Sandoval, Mayo Clinic, La Crosse, WI; Amy Saenger, Hennepin County Medical Ctr, Minneapolis, MN; Andrew Chapman, Ctr for Cardiovascular Science, Edinburgh, United Kingdom; Nicholas L Mills, Univ Edinburgh, Edinburgh, United Kingdom; Martin Than, Christchurch Hosp, Christchurch, New Zealand; John Pickering, Univ of Otago, Christchurch, New Zealand; Andrew Worster, McMaster Univ, Hamiltion, ON, Canada; Peter Kavsak, McMaster Univeristy, Hamilton, ON, Canada; Anne Sexter, CDRG / HHRI, Minneapolis, MN; Karen Schulz, HHRI/Hennepin County Medical Ctr, Minneapolis, MN; William Frank Peacock, Baylor Coll of Med, Houston, TX; **Fred S Apple** , Hennepin County Medical Ctr, Minneapolis, MN

3:00 PM

Board # 4018

Classification, Investigation and Management of Patients With Myocardial Injury and Infarction: A Cross-Sectional Survey of Clinical Practice

**Andrew R Chapman** , Simran Piya, John Hung, Stacey Stewart, Marwa Daghem, Justin Chiong, Lucy Marshall, Amy Ferry, Fiona E Strachan, Marc Dweck, Univ of Edinburgh, Edinburgh, United Kingdom; David Ernest Newby, Univ of Edinburgh, Edinbugh, United Kingdom; Nicholas L Mills, Univ of Edinburgh, Edinburgh, United Kingdom

3:00 PM

Board # 4019

Prognostic Value of Skeletal Muscle Loss With Abnormal Abdominal Fat Distribution in Patients With St-segment Elevation Myocardial Infarction

**Ryosuke Satou** , Yokohama City Univ, Yokohama City, Japan; Kozo Okada, Yokohama City Univ, Yokohama, Japan; Eiichi Akiyama, Yokohama City Univ Medical Ctr, Yokohama, Japan; Yasushi Matsuzawa, Yokohama City Univ, Yokohama, Japan; Masaaki Konishi, Yokohama City Univ, Yokohama, Japan; Nobuhiko Maejima, Yokohama City Univ Medical Ctr, Yokohama, Japan; Noriaki Iwahashi, Kiyoshi Hibi, Masami Kosuge, Yokohama City Univ, Yokohama, Japan; Kouichi Tamura, Yokohama City Univ Graduate Sch of Med, Yokohama City, Japan; Toshiaki Ebina, Yokohama City Univ, Yokohama City, Japan; Kazuo Kimura, Yokohama City Univ, Yokohama, Japan

3:00 PM

Board # 4020

Impact of New Onset Atrial Fibrillation on Long-term Mortality According to Renal Function in Acute Myocardial Infarction

**Nicola Cosentino** , Jeness Campodonico, Marco Ballarotto, Valentina Milazzo, Marco Moltrasio, Ctr Cardiologico Monzino, Milan, Italy; alice Bonomi, Ctr Cardiologico Monzino, Milano, Italy; Katia Celentano, Monica De Metrio, Mara Rubino, Ctr Cardiologico Monzino, Milan, Italy; Simonetta Genovesi, Nephrology Unit, Milan, Italy; Giancarlo Marenzi, Ctr Cardiologico Monzino, IRCCS, Milan, Italy

3:00 PM

Board # 4021

Admission Cortisol Levels Are Associated to Risk Factors and Mortality in Acute Coronary Syndrome

Jose M Aladio, Diego Costa, **Maia Matsudo** , Sandra Patricia Swieszkowski, Alejandra Scazziota, Diego Gonzalez, Alejandra Brignoli, Ricardo Perez de la Hoz, Hosp de Clinicas Jose de San Martin, Buenos Aires, Argentina

# Abstract Poster Session

## EP.APS.19 - Nutrition and Nutritional Biomarkers

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 3113

Higher Plasma EPA, EPA/AA and DHA Levels Are Associated With Lower Incident MACE Both in Those With and Without Angiographic CAD

**Viet T Le** , Intermountain Medical Ctr, Rocky Mountain Univ of Health Professions, Salt Lake City, UT; Kirk Ute Knowlton, Raymond O McCubrey, Intermountain Medical Ctr, Salt Lake City, UT; Stacey Knight, Intermountain Medical Ctr, Murray, UT; Mohit Jain, Jeramie D Watrous, Khoi Dao, Mahan Najhawan, Univ of California San Diego, La Jolla, CA; Tami L Bair, Intermountain Medical Ctr, Salt Lake Cty, UT; Benjamin D Horne, Intermountain Heart Inst, Univ of Utah, Salt Lake City, UT; Joseph Brent Muhlestein, Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT; Donald L Lappe, Madisyn Taylor, Intermountain Medical Ctr, Salt Lake City, UT; Jeffrey Lance Anderson, Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT

3:00 PM

Board # 3114

Effects of Marine Omega-3 Supplementation on Fatty Acids and Bioactive Lipids and Associations With Risk of Cardiovascular Disease: Secondary Analysis From the Randomized Vitamin D and Omega-3 Trial (VITAL)

**Olga Demler** , Yanyan Liu, Brigham and Women's Hosp, Brookline, MA; Jeramie Watrous, Univ of California at San Diego, La Jolla, CA; Heike Gibson, Harvrrd Sch of Public Health, Boston, MA; Kim Lagerborg, Harvard Medical Sch, Boston, MA; Hesam Dashti, Mallory Heath, Brigham and Women's Hosp, Boston, MA; Carlos A. Camargo Jr., Massachusetts Gen Hosp, Boston, MA; William S Harris, OmeagaQuant Analytics, Sioux Falls, SD; Jay G Wohlgemuth, Quest Diagnostics, San Juan Capistrano, CA; Mahan Najhawan, Khoi Dao, UCSD, La Jolla, CA; James Prentice, Quest Diagnostics, San Juan Capistrano, CA; Julia A Larsen, Quest Diagnostics, Inc., Alameda, CA; Olivia Okereke, Mass General Hosp, Boston, MA; Karen Costenbader, Brigham and Women's Hosp, Belmont, MA, MA; Julie E Buring, Brigham and Women's Hosp, Brookline, MA; Vasan S Ramachandran, Framingham Heart Study, Framingham, MA; Joann E Manson, Brigham and Women's Hosp, Brookline, MA; Susan Cheng, Cedars-Sinai Medical Ctr, Los Angeles, CA; Mohit Jain, Univ. of California - San Diego, La Jolla, CA; Samia Mora, Brigham and Women's Hosp, Brookline, MA

3:00 PM

Board # 3115

Impact of a Plant-Based Nutrition Intervention on the 10-Year Ascvd Risk in African Americans

**Setri Fugar** , Ibtihaj A m Fughhi, Rush Univ Medical Ctr, Chicago, IL; Ronald McDaniel, Boston Heart Diagnostics, Chicago, MA; Sharon Gates, Stephen Sawyer, Rush Univ Medical Ctr, Chicago, IL; Terry Mason, Cook County Dept of Public Health, Chicago, IL; Kim Allan Williams Sr., Rush Univ Medical Ctr, Chicago, IL

3:00 PM

Board # 3116

Does Supplementation to Higher Plasma Omega-3 Levels Predispose to Prostate Cancer? Results From the Intermountain INSPIRE Biobank Registry

Viet T Le, Intermountain Medical Ctr, Rocky Mountain Univ of Health Professions, Salt Lake City, UT; Kirk Ute Knowlton, Intermountain Medical Ctr, Salt Lake City, UT; Mohit Jain, Univ. of California - San Diego, La Jolla, CA; Raymond O McCubrey, Stacey Knight, Intermountain Medical Ctr, Salt Lake City, UT; Mahan Najhawan, Khoi Dao, Jeramie Watrous, Univ of California San Diego, La Jolla, CA; Tami L Bair, Intermountain Medical Ctr, Salt Lake Cty, UT; Benjamin D Horne, Joseph Brent Muhlestein, Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT; Donald L Lappe, IMC Hosp, Murray, UT; John F Carlquist, Intermountain Medical Ctr, Univ of Utah, Murray, UT; **Jeffrey Lance Anderson** , Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT

3:00 PM

Board # 3117

Effect of Omega-3 Fatty Acids on Progression of Coronary Artery Calcium Score in Subjects With Stable Coronary Artery Disease on Statin Therapy

**Maral Amangurbanova** , Bhavya Vemuri, Abdul Aziz Asbeutah, Beth Israel Deaconess Medical Ctr/ Harvard Medical Sch, Boston, MA; Essa H Hariri, UMass Medical Sch, Worcester, MA; Francine K Welty, Harvard Medical Sch, Brookline, MA

3:00 PM

Board # 3118

Associations of Circulating Trimethylamine-n-Oxide (TMAO) With Dietary Intakes and Cardiometabolic Biomarkers: Results From the TMAO Pooling Project

Jae Jeong Yang, Xiao-Ou Shu, Vanderbilt Univ Medical Ctr, Nashville, TN; David M Herrington, Wake Forest Sch of Med, Winston Salem, NC; Steven C Moore, Natl Cancer Inst, Bethesda, MD; Katie A Meyer, Univ of North Carolina at Chapel Hill, Chapel Hill, NC; Jennifer Ose, Univ of Utah, Salt Lake City, UT; Cristina Menni, King's Coll London, London, United Kingdom; Nicholette D Palmer, Wake Forest Sch of Med, Winston-Salem, NC; Wei Zheng, Vanderbilt Univ Medical Ctr, Nashville, TN; Sei Harada, Keio Univ Sch of Med, Tokyo, Japan; Huilian Zhu, Sun Yat-sen Univ, Guangzhou, China; Demetrius Albanes, Natl Cancer Inst, Bethesda, MD; Thomas J Wang, Vanderbilt Univ Medical Ctr, Nashville, TN; Cornelia M Ulrich, Univ of Utah, Salt Lake City, UT; Myriam Fornage, Univ of Texas Health Science Ctr, Houston, TX; Qiuyin Cai, Vanderbilt Univ Medical Ctr, Nashville, TN; Charles E Matthews, Natl Cancer Inst, Bethesda, MD; Fang-Chi Hsu, Wake Forest Sch of Med, Winston-Salem, NC; Yong-Bing Xiang, Shanghai Jiaotong Univ Sch of Med, Shanghai, China; Robert E Gerszten, Beth Israel Deaconess Medical Ctr, Boston, MA; Hui Cai, **Danxia Yu** , Vanderbilt Univ Medical Ctr, Nashville, TN

3:00 PM

Board # 3119

The Relationship Between Atrial Fibrillation and Coffee

**Nandini Mehra** , Christopher DeSimone, David Hodge, Abhishek Deshmukh, Alexander C Egbe, Malini Madhavan, Mayo Clinic, Rochester, MN

3:00 PM

Board # 3120

High Sodium Intake is Associated With Heart Failure Hospitalization in Patients With Older Age, Low Body Weight, and Female: Subanalysis of the Esprit, Evaluation of Sodium Intake for the Prediction of Cardiovascular Events in Japanese High-risk Patients, Cohort Study

**Tsuneaki Sadanaga** , Seigato Hosp, Kumamoto, Japan; Shinichi Hirota, Ueki Hosp, Kumamoto, Japan; Hideo Mitamura, Tachikawa Hosp, Tokyo, Japan

3:00 PM

Board # 3121

Associations of Ideal Diet Behaviours With Heart Age and 10 Year Risk of Cardiovascular Events

**Long Zhou** , Yan Yu, Xi'an Jiaotong Univ, Xi'an, China

# Abstract Poster Session

## EP.APS.15 - Oncocardiology: Therapeutic Effects, Adverse Effects and Outcomes

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 3073

Early Captopril Treatment Mitigates Doxorubicin Cardiomyopathy in Mice: A Cardiac MRI Pilot Study

**George M. Cater** , UPMC, Pittsburgh, PA; Samuel K. Wyman, Nathan Salamacha, Ryan Marsden, Shanim Manzoor, Brendan Sestokas, Univ of Pittsburgh, Pittsburgh, PA; Erik B. Schelbert, Timothy C. Wong, UPMC, Pittsburgh, PA; Yijen L. Wu, Univ of Pittsburgh, Pittsburgh, PA

3:00 PM

Board # 3074

Soluble Urokinase Plasminogen Activator Receptor Levels Rise in Response to Cardiotoxic Chemotherapy Independent of Global Longitudinal Strain

**Maria Devanesan** , Rush Univ Medial Ctr, Chicago, IL; Issam Atallah, St. Luke's Hosp, Chesterfield, MO; Hannah Gaddam, Univ of Illinois at Urbana-Champaign, Urbana, IL; Kelli Jones, Beata Samelko, Todd Beck, Yanyu Zhang, Changli Wei, Rush Univ Medial Ctr, Chicago, IL; Lothar A Blatter, Rush Univ, Chicago, IL; Steven B Feinstein, Rush Univ Medical Ctr, Highland Park, IL; Jochen Reiser, Rush Univ Medical Ctr, Chicago, IL; Kathrin Banach, Rush Univ Medial Ctr, Chicago, IL; Salim Hayek, Univ of Michigan, Ann Arbor, MI; Tochi M Okwuosa, Rush Univ, Chicago, IL

3:00 PM

Board # 3075

Coronary Microvascular Dysfunction is Associated With Worse Outcomes in Patients With Thoracic Malignancy

**Sanjay Divakaran** , Jesse P. Caron, Wunan Zhou, Jon Hainer, Josh Klein, Courtney F. Bibbo, Hicham Skali, Brigham and Women's Hosp, Boston, MA; Viviany R Taqueti, Brigham Women's Hosp, Boston, MA; Ron Blankstein, Brigham and Women's Hosp, Boston, MA; Sharmila Dorbala, Brigham and Women's, Boston, MA; Mandeep R Mehra, Anju Nohria, John D Groarke, Brigham and Women's Hosp, Boston, MA; Marcelo F Di Carli, Brigham and Womens Hosp, Boston, MA

3:00 PM

Board # 3076

The Impact of Anthracycline-Based Chemotherapy on Left Ventricular Function: All Doses Matter

**Hua Zhong** , Peking Union Medical Coll Hosp, Beijing, China; Bhoomi Mehrotra, Sherly Jacob-Perez, Kristine Bond, Nathaniel Reichek, Haoyi Zheng, St. Francis Hosp, Roslyn, NY

3:00 PM

Board # 3078

High Flow Oxygen to Improve Cardiac Autonomic Dysfunction During Exercise in Advanced Cancer: A Pilot Study

**Tushar Ramesh** , Conrad J Fernandes, Michelle Seymour, Baylor Coll of Med, Houston, TX; Kara Thompson, UT MD Anderon Cancer Ctr, Houston, TX; Juan Lopez-Mattei, UT MD Anderson Cancer Ctr, Houston, TX; David Hui, UT MD Anderon Cancer Ctr, Houston, TX

3:00 PM

Board # 3079

Atrial Fibrillation, Heart Failure and Bleeding Risk in Patients on Bruton Tyrosine Kinase Inhibitor Therapy- Results From a Tertiary Care Center

**Manik Veer** , Abhishek Chaturvedi, Mitha Naik, Allegheny General Hosp, Pittsburgh, PA; Amit Thosani, Allegheny, Pittsburgh, PA; Indu G Poornima, Allegheny General Hosp, Pittsburgh, PA

3:00 PM

Board # 3080

The Impact Of Sepckle Tracting Echocardiography In Patient With Lymphoma Receiving Chemotherapy

Hsien-Yuan Chang, Chun-Hui Lee, **Yen-Wen Liu** , Natl Cheng Kung Univ Hosp, Tainan, Taiwan

3:00 PM

Board # 3081

A Risk Prediction Model for Hemorrhagic Events in Elderly Patients With Coronary Artery Disease and Malignant Gastrointestinal Tumors

**Nandi Bao** , Yabin Wang, Ran Zhang, Hebin Che, Huitao Wu, Wenwen Meng, Jiaxin Miao, Danyang Li, Wanguo Xue, Li Fan, Feng Cao, Chinese PLA General Hosp, Beijing, China

3:00 PM

Board # 3082

A Tumor Suppressive Circular RNA CircITCH Ameliorates Doxorubicin-Induced Cardiotoxicity by Reducing Oxidative Injury and DNA Damage Through Regulation of Mir-330-5p/sirt6 Axis

**Dong Han** , Chinese PLA general hospital, Beijing, China; Yongjun Wang, Union Hosp of Tongji Medical Coll, Huazhong Univ of Science and Technology, Wuhan, China; Feng Cao, Dept of Cardiology, Chinese PLA General Hosp, Beijing, China

3:00 PM

Board # 3083

Cardiac Effects of Mitogen-activated Protein Kinase Inhibitors in Children

**Jennifer A. Su** , Nathan J. Robison, Jemily Malvar, Jondavid Menteer, Children's Hosp Los Angeles, Los Angeles, CA

# Abstract Poster Session

## VA.APS.05 - Pathways to Improved Outcomes in Venous Thromboembolism: The Year in Discovery Part II

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Poster Professor

Geoffrey Barnes, Ann Arbor, MI

3:00 PM

Board # 4357

Effect of a Multidisciplinary Pulmonary Embolism Response Team on Outcomes in Elevated-Risk Acute Pulmonary Embolism

Brett Carroll, **Tyler Mehegan** , Jeffrey J Weinstein, Beth Israel Deaconess Medical Ctr, Boston, MA; Kenneth Bauer, Margaret Hayes, Beth Israel Deaconess Medical Ctr, Boston, MA; Louis M Chu, Beth Israel Deaconess Med Ctr, Brighton, MA; Andrew Locke, Beth Israel Deaconess Med Ctr, Brighton, MA, Boston, MA; Anuradha Godishala, Beth Israel Deaconess Med Ctr, Brighton, MA, Boston, MA, Boston, MA; Andrew Dicks, Beth Israel Deaconess Med Ctr, Brighton, MA, Boston, MA, Boston, MA, Boston, MA; Kevin Soriano, Beth Israel Deaconess Med Ctr, Brighton, MA, Boston, MA, Boston, MA, Boston, MA, Boston, MA; Jaya Kanduri, BIDMC, Boston, MA; Kelsey Sack, BIDMC, Boston, MA, Arlington, MA; Mason Marcus, BIDMC, Boston, MA; Cara Wiest, BIDMC, Boston, MA, Boston, MA; Abby Pribish, BIDMC, Boston, MA, Boston, MA, Brookline, MA; Eric A Secemsky, BIDMC, Newton, MA; Duane S Pinto, Beth Israel Deaconess Medical Ctr, Boston, MA

3:00 PM

Board # 4358

Early Restoration of Blood Flow Improves Venous Thrombosis Resolution and Vein Wall Fibrosis: Implications for Reducing the Post-Thrombotic Syndrome

**Wenzhu Li** , Chase W Kessinger, Cardiovascular Res Ctr, Boston, MA; Makoto Orii, Jie Cui, Cardiovascular Res Ctr, MGH, Boston, MA; Stephan Kellnberger, Massachusetts General Hosp, Boston, MA; Adam Mauskapf, Cardiovascular Res Ctr, Boston, MA; Lang Wang, Massachusetts General Hosp, Malden, MA; Xiaoxin Zheng, Ahmed A Tawakol, Massachusetts General Hosp, Boston, MA; Michael R Jaff, Newton-Wellesley Hosp, Newton, MA; Peter Libby, Brigham and Women's Hosp, Boston, MA; Peter Henke, Univ of Michigan, Ann Arbor, MI; Farouc A Jaffer, Massachusetts General Hosp, Boston, MA

3:00 PM

Board # 4360

Meta-Analysis of the Efficacy, Safety and Cost-Benefit of Direct Oral Anticoagulation for Extended Venous Thromboembolism Prophylaxis in Medically Ill Patients Post-Hospitalization

**Olivia Lamping** , Ahmed Abdel-Latif, Meenakshi Bhalla, Univ of Kentucky, Lexington, KY; Susan S Smyth, Univ of Kentucky, Lexington; Vikas Bhalla, Univ of Kentucky, Lexington, KY

3:00 PM

Board # 4361

Can Pulmonary Embolism Severity Index (PESI) Score Predict Readmission Rates in Patients With Pulmonary Embolism?

**Reshma Reddy Golamari** , Mercy Catholic Medical Ctr, Philadelphia, PA; Shambo Guha Roy, Shengnan Zheng, Melissa Alvarez, Karthik Ramireddy, Christian Pedersen, Mercy Catholic Medical Ctr, Darby, PA

3:00 PM

Board # 4362

Time Course and Outcomes of Major Bleeding Events According to Bleeding Site in Patients Receiving Anticoagulant Therapy for Venous Thromboembolism

**Behnood Bikdeli** , Columbia Univ Medical Ctr, New York, NY; Fares Moustafa, Clermont-Ferrand Univ Hosp, Clermont-Ferrand, France; José Antonio Nieto, Hosp Virgen de la Luz, Cuenca, Spain; Alfred Ian Lee, Yale Cancer Ctr and Yale Univ Sch of Med, New Haven; Nuria Ruíz-Giménez, Hosp Univrio de La Princesa, Madrid, Spain; Alicia Lorenzo, Hosp Univrio La Paz, Madrid, Spain; Sebastian M Schellong, Municipal Hosp Friedrichstadt, Friedrichstadt; Silvia Soler, Hosp Olot i Comarcal de la Garrotxa, Gerona, Spain; Maria Del Valle Morales, Hosp del Tajo, Madrid, Spain; Marijan Bosevski, Columbia Univ Medical Ctr, Skopje, Macedonia, The Former Yugoslav Republic of; Olga Gavín, Hosp Clínico Univrio Lozano Blesa, Zaragoza, Spain; Gregory Lip, Ctr for Cardiovascular Sciences, Birmingham, United Kingdom; Manuel Monreal, Hosp Germans Trias i Pujol, Badalona, Spain

3:00 PM

Board # 4363

Impact of Bariatric Surgery on Long-Term Venous Thromboembolic Risk: A Matched Cohort Study

**Maddalena Ardissino** , Osama Moussa, Alice Tang, Laura Lazzari, Ophelia Millar, Paul Ziprin, Ara Darzi, Imperial Coll London, London, United Kingdom; Omar Khan, St George's Univ Hosp, London, United Kingdom; Peter Collins, Royal Brompton, London; Sanjay Purkayastha, Imperial Coll London, London, United Kingdom

3:00 PM

Board # 4365

Changing Treatment Patterns in Asians With Venous Thromboembolism

**Li Yi-heng** , Cheng-Han Lee, Hui-Wen Lin, Sheng-Hsiang Lin, Natl Cheng Kung Univ Hosp, Tainan, Taiwan

3:00 PM

Board # 4366

Prevalence and Outcomes of Heparin-Induced Thrombocytopenia in Patients With Venous Thromboembolic Disease - Insight From National Inpatient Sample

**Neal B. Shah** , Temple Univ Hosp, Philadelphia, PA; Parija Sharedalal, Drexel Univ Hosp, Philadelphia, PA; Alice Tang, Huaqing Zhao, Vladimir Lakhter, Temple Univ Hosp, Philadelphia, PA; Raghu Kolluri, Ohio Health, Dublin, OH; Riyaz Bashir, Temple Univ, Philadelphia, PA

3:00 PM

Board # 4367

Progression of Asymptomatic Carotid Artery Stenosis and the Incidence of Stroke

**Hussain Basrawala** , Patrick Baghdasaryan, Hartaj S Girn, Jonathan Nattiv, Han Tun, Leonardo Clavijo, David Shavelle, Parveen Garg, USC, Los Angeles, CA

3:00 PM

Board # 4368

Assessment of Generalizability in Phase 3 Clinical Trials of Direct Oral Anticoagulants by Eligibility to Trials and Outcomes of Real World Patients With Non-Valvular Atrial Fibrillation

**Mayumi HIga** , Kaori Une, Shinichiro Ueda, Univ of the Ryukyus, Nishihara-cho, Japan; Ryukyu Anticoagulation Registry Study Group

3:00 PM

Board # 4369

Prospective Study of Adiponectin and Von Willebrand Factor for Clinical Outcomes After 3 Years in Non-Valvular Atrial Fibrillation

**Danielle Vlazny** , Mayo Clinic, Rochester, MN; Robert D. McBane II, Mayo Clinic and Fndn, Rochester, MN; Rowlens M Melduni, Mayo Clinic, Rochester, MN; Naser Mahmud Ammash, Mayo Med Ctr, Rochester, MN; Ewa Agnieszka Konik, Ana I Casanegra, Mayo Clinic, Rochester, MN; Matylda Mazur, Wake Forest Univ, Winston Salem, NC; Damon Houghton, Josh Slusser, Diane Grill, Mayo Clinic, Rochester, MN; Waldemar E Wysokinski, Mayo Clinic Rochester, Rochester, MN

3:00 PM

Board # 4370

Twelve-Month Direct Oral Anticoagulant Treatment Ameliorates Cerebral Blood Flow but Not Brain Natriuretic Peptide, as Evaluated by Brain Perfusion Single-Photon Emission Computed Tomography

**Hidekazu Takeuchi** , Takeuchi Naika Clinic, Ogachi, Japan

# Abstract Poster Session

## EA.APS.19 - Pharmacologic Treatment of Arrhythmias

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 2122

Proton Pump Inhibitor Decrease the Risk of Upper Gastrointestinal Bleeding in Anticoagulation Treatment: A Systematic Review and Meta-Analysis

**Wasawat Vutthikraivit** , Sakolwan Suchartlikitwong, Texas Tech Health Sciences Ctr, Lubbock, TX; Pattara Rattanawong, Univ of Hawaii, Honolulu, HI; Mohamed Elmassry, Texas Tech Univ Health S C, Lubbock, TX; Pablo Paz, Texas Tech Univ Health Sciences Ctr, Lubbock, TX; Barbara Mantilla, TBD, Lubbock, TX; M Rubayat Rahman, Texas Tech Univ, Lubbock, TX; Saif El Nawaa, Texas Tech Univ HSC, Lubbock, TX; Genanew Bedanie, Texas Tech Univ Health Sciences Ctr, Lubbock, TX; Mohammad M Ansari, Texas Tech Univ, Lubbock, TX

3:00 PM

Board # 2123

Long-Term Outcomes in Patients Treated With Flecainide for Premature Ventricular Contractions or Ventricular Tachycardia With Stable Coronary Artery Disease

**Thomas Jared Bunch** , Intermountain Medical Ctr, Salt Lake City, UT; Heidi T May, Intermountain Medical Ctr, Murray, UT; Jalisa Cruz, Intermountain Medical Ctr, Salt Lake City, UT; Tami L Bair, Intermountain Medical Ctr, Salt Lake Cty, UT; J. Peter Weiss, John D Day, Brian Crandall, Michael J Cutler, Jeffrey S Osborn, Charles Mallender, Intermountain Medical Ctr, Salt Lake City, UT; Jeffrey Lance Anderson, Intermountain Medical Ctr, Murray, UT; Joseph Brent Muhlestein, Kirk Ute Knowlton, Intermountain Medical Ctr, Salt Lake City, UT

3:00 PM

Board # 2124

Long-Term Outcomes in Patients Treated With Flecainide for Atrial Fibrillation With Severe Coronary Artery Disease Treated With Revascularization

**Thomas Jared Bunch** , Intermountain Medical Ctr, Salt Lake City, UT; Heidi T May, Intermountain Medical Ctr, Murray, UT; Jalisa Cruz, J. Peter Weiss, John D Day, Brian G Crandall, Michael J Cutler, Jeffrey S Osborn, Charles Mallender, Jeffrey L Anderson, Joseph Brent Muhlestein, Kirk U Knowlton, Intermountain Medical Ctr, Salt Lake City, UT

3:00 PM

Board # 2125

Sodium Channel Blockers Normalize Cardiac Repolarization in Rett Syndrome

**Hoang H Nguyen** , Rush Univ Medical Coll, Chicago, IL; John Somberg, Rush Univ, Lake Bluff, IL; Mary Wilkie, Rush Univ Medical Coll, Chicago, IL; Jessica Jacobson, Rush Univ Medical Ctr, Chicago, IL; Colleen Buhrfiend, Peter Heydemann, Rush Univ Medical Coll, Chicago, IL

3:00 PM

Board # 2126

Removal of Dabigatran Using Sorbent Hemadsorption- Influence on Aptt Values

Alexandra A Angheloiu, Temple Univ, Philadelphia, PA; **George O Angheloiu** , Univ of Pittsburgh Medical Ctr, Williamsport, PA

3:00 PM

Board # 2129

Does 3 Weeks of Anticoagulation With a Novel Oral Anticoagulant Obviate the Need for Transesophageal Echocardiography Before Cardioversion?

**Carine Basmadjian** , Cooper Univ Hosp, Camden, NJ; Mihir Jani, Cooper Medical Sch of Rowan Univ, Camden, NJ; Zubair Khan, Cardiovascular Services at North Alabama Medical Ctr, Florence, AL; John Andriulli, Cooper Univ Hosp, Camden, NJ; Andrea M Russo, Cooper Univ Hosp, Moorestown, NJ; Matthew Ortman, Cooper Univ Hosp, Camden, NJ

3:00 PM

Board # 2130

EVALUATION OF NOVEL ORAL ANTICOAGULANT PRESCRIPTION PATTERNS IN A TERTIARY CARE CLINIC

**Yana Shamiss** , Pouria Alipour, Zahra Azizi, Southlake Regional Health Ctr, Newmarket, ON, Canada; Hadi Tohidi, Southlake Regional Helath Ctr, Newmarket, ON, Canada; Alexander Shusterman, Hodaya Lightstone, Southlake Regional Health Ctr, Newmarket, ON, Canada; Stacey Morris, Southlake Regional Health Ctr, Thornhill, ON, Canada; Sereena Nath, Southlake Regional Health Ctr, Newmarket, ON, Canada; Nina Varah, Southlake Regional Health Ctr, Hamilton, ON, Canada; Sarah Donegan, Southlake Regional Health Ctr, Newmarket, ON, Canada; Alona Avoulov, Southlake Regional Health Ctr, Toronto, ON, Canada; Claire Jansen, Southlake Regional Health Ctr, Bradford, ON, Canada; Sara Tamjidi, Southlake Regional Health Ctr, Newmarket, ON, Canada; Yaariv Khaykin, Southlake Regional Health Ctr, Richmond Hill, ON, Canada

3:00 PM

Board # 2131

Low Ionized Calcium in Ventricular Fibrillation and Torsades De Pointes

**Antonio R Delgado-Almeida** , Univ de Carabobo Medical Sch, Valencia, Venezuela, Bolivarian Republic of; Maria Carolina Delgado-Lelievre, Univ of Miami Medical Sch, Doral, FL; Carlos Luis Delgado, Univ de Carabobo, Valencia, Venezuela, Bolivarian Republic of

3:00 PM

Board # 2132

Vernakalant Compared to Anti-arrhythmic Drugs for Rapid Cardioversion of Early Onset Atrial Fibrillation: A Meta-analysis

**Chintan G Trivedi** , Sanghamitra Mohanty, Domenico Giovanni Della Rocca, Carola Gianni, Texas Cardiac Arrhythmia Inst, Austin, TX; Luigi Di Biase, Albert Einstein Coll of Med, New York, NY; Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

# Abstract Poster Session

## EP.APS.21 - Sex Differences in Epidemiology of Cardiovascular Diseases

#### Zone 3, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 3133

Development and Validation of a Risk Prediction Model for Cardiovascular Disease in Women of Reproductive Age

**Sonia M Grandi** , Kristian B Filion, McGill Univ, Montreal, QC, Canada; Jennifer A Hutcheon, Univ of British Columbia, Vancouver, BC, Canada; Graeme N Smith, Queen's Univ, Kingston, ON, Canada; Robert W Platt, McGill Univ, Montreal, QC, Canada

3:00 PM

Board # 3134

Relationship of Right and Left Atrial Volumes by Sex and Age Group in Healthy Adults

**Saadia Qazi** , Univ of Massachusetts Medical Sch, Worcester, MA; Philimon N Gona, Univ of Massachusetts Boston, Boston, MA; Garima Arora, Univ of Alabama, Birmingham, AL; Carol Salton, Beth Israel Deaconess Medical Ctr, Boston, MA; Christopher J O'Donnell, Boston VAMC, Boston, MA; Warren J Manning, Michael L Chuang, Beth Israel Deaconess Medical Ctr, Boston, MA

3:00 PM

Board # 3135

Gender Differences in the Association of Metabolic Syndrome and LDL Cholesterol With Incident Cerebro-Cardiovascular Disease Among Koreans Without Diabetes Mellitus: A National Population-Based Study

**Sung Gyun Ahn** , So-Young Kim, Tae-Hwa Go, Dae-Ryong Kang, Jang Young Kim, Yonsei Univ Wonju Coll of Med, Wonju, Korea, Republic of

3:00 PM

Board # 3136

Trends in Heart Disease Mortality by Subtype in Black and White Men and Women in The United States, 1999-2017

**Nilay S Shah** , Rebecca Molsberry, Donald M Lloyd-Jones, Mercedes R Carnethon, Northwestern Univ, Chicago, IL; Sadiya S. Khan, Northwestern Univ, Oak Park, IL

3:00 PM

Board # 3137

Sex and Racial Differences in Acute Myocardial Infarction Treatment and Outcomes

**Erica N. Schorr** , Bradly Watarai, Stephanie Jarosek, Univ of Minnesota, Minneapolis, MN

3:00 PM

Board # 3138

Confounding and Mediation of the Association Between Psychological Attitudes and Type 2 Diabetes Risk Among Postmenopausal Women

**Meredith S Duncan** , Vanderbilt Univ Medical Cntr, Nashville, TN; Matthew S Freiberg, Vanderbilt Univ, Nashville, TN; Simin Liu, Brown Univ, Providence, RI; Lewis H Kuller, Univ of Pittsburgh, Pittsburgh, PA; Jie Li, Brown Univ, Providence, RI; Aladdin Shadyab, Univ of California San Diego, La Jolla, CA; Jaimie Hunter, Wake Forest Sch of Med, Winston-Salem, NC; Milagros C Rosal, UMASS Medical Sch, Worcester, MA; Juhua Luo, Indiana Univ, Bloomington, IN; Hilary A. Tindle, Vanderbilt Univ, Nashville, TN

3:00 PM

Board # 3139

While Acute Myocardial Infarction-related Hospitalizations and Mortality in Most Californians Declined From 2005-2014, Young Women Had Increased Hospitalizations

Buddhika M Ratnasiri, Univ of California Berkeley, Berkeley, CA; Ezra A Amsterdam, Univ of California Davis, Sch of Med, Sacramento, CA; Radhika Bukkapatnam, UC Davis, Folsom, CA; **Anura W.G. Ratnasiri** , Steven S Parry, Ralph J DiLibero, California Dept of Health Care Services, Sacramento, CA; Javier E Lopez, UC Davis, Davis, CA

3:00 PM

Board # 3140

Sex-, Age-, and Metabolic Disorder-Dependent Distributions of Selected Inflammatory Biomarkers Among Community-Dwelling Adults: The Cardiovascular and Metabolic Diseases Etiology Research Center Cohort

**So Mi Jemma Cho** , Hokyou Lee, Jee-Seon Shim, Hyeon Chang Kim, Yonsei Univ Coll of Med, Seoul, Korea, Republic of

3:00 PM

Board # 3141

Trends in Incidence and Mortality From Atrial Fibrillation/Flutter Across the United States: 1990 to 2017

**Augustin DeLago** , Justin D Salciccioli, Mount Auburn Hosp, Cambridge, MA; Dominic C Marshall, Univ of Oxford, Oxford, United Kingdom; Binu Philips, Mount Auburn Hosp, Cambridge, MA

3:00 PM

Board # 3142

Sex and Race Differences in Heart Failure Risk in Late Life: The Atherosclerosis Risk in Communities (ARIC) Study

Alvin Chandra, Hicham Skali, Brian Claggett, Brigham and Women's Hosp, Boston, MA; Joseph Rossi, Univ of North Carolina, Sanford, NC; Patricia Chang, Univ of North Carolina, Chapel Hill, NC; Stuart D Russell, Duke Univ Medical Ctr, Raleigh, NC; Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD; Dalane W Kitzman, Wake Forest Baptist Health, Winston Salem, NC; Suma H Konety, Univ Minnesota, Minneapolis, MN; Thomas Mosley, Univ MS Medical Ctr, Jackson, MS; Scott D Solomon, **Amil M Shah** , Brigham and Women's Hosp, Boston, MA

# Abstract Poster Session

## CH.APS.13 - Technical Issues in Congenital Heart Surgery

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 4041

Outcomes Forextracorporeal Membrane Oxygenation Support for Failure to Wean From Cardiopulmonary Bypass After Pediatric Cardiac Surgery

**Francesca Sperotto** , Ravi R Thiagarajan, Childrens Hosp Boston, Boston, MA; Paola Cogo, Bambino Gesu Children's Hosp, Rome, Italy; Angelo Polito, Univ Hosp of Geneva, Geneva, Switzerland

3:00 PM

Board # 4042

Hyperoxia During Cardiopulmonary Bypass is Associated With Mortality in Infants Undergoing Cardiac Surgery

**Asaad Beshish** , Children's Healthcare of Atlanta, Atlanta, GA; Andrew Shin, Stanford Children's Health, Menlo Park, CA; Ozzie Jahadi, Ashley Mello, Lucile Packard Children's Hosp, Palo Alto, CA; Vamsi Yarlagadda, David M Kwiatkowski, Stanford Univ Sch of Med, Palo Alto, CA

3:00 PM

Board # 4044

Coil Embolization in Aortopulmonary Collateral Arteries Before Fontan Surgery Ameliorates the Postoperative Course

**Hirofumi Saiki** , Kitasato Univ, Sagamihara Kanagawa, Japan; Manabu Takanashi, Kitasato Univ Hosp, Sagamihara, Japan; Seiko Kuwata, Kitasato Univ, Kanagawa, Japan; Satoshi Masutani, Saitama Medical Univ, Saitama-ken, Japan; Hideaki Senzaki, Kitasato Univ, Kanagawa, Japan

3:00 PM

Board # 4045

Biventricular Repair of Double-Outlet Right Ventricle With Non-Committed Ventricular Septal Defect Using Intraventricular Conduit

Ting Lu, Central South Univ, Changsha, China; Jia Li, Guangzhou Women and Children's Medical Ctr, Guangzhou, China; Jianguo Hu, Can Huang, Ling Tan, Qin Wu, **Zhongshi Wu** , Central South Univ, Changsha, China

3:00 PM

Board # 4046

Outcomes Following Single Stage Repair of Truncus Arteriosus and Interrupted Aortic Arch

**Hussain Rao** , Noor Alshami, Mohammed Hasan, Amber Leila Sarvestani, Univ of Missouri-Kansas City Sch of Med, Kansas City, MO; Elizabeth Turk, Children's Mercy Hosp, Kansas City, MO; Amanda S Thomas, Lazaros Kochilas, Emory Univ Sch of Med, Atlanta, GA; Geetha Raghuveer, Children's Mercy Hosp, Kansas City, MO

3:00 PM

Board # 4047

Airway Clearance Deficit in Infants Undergoing Congenital Cardiac Surgery

**Phillip S Adams** , Timothy Corcoran, Michael Czachowski, Univ of Pittsburgh, Pittsburgh, PA; Alvin Lee Saville, Children's Hosp of Pittsburgh of UPMC, Glenshaw, PA; Jiuann-Huey Ivy Lin, Children's Hosp of Pittsburgh, Pittsburgh, PA; Yuliya Domnina, Tracy Baust, Omar Khalifa, Maliha Zahid, Univ of Pittsburgh, Pittsburgh, PA; Joan Sanchez-de-Toledo, Children's Hosp of Pittsburgh, Pittsburgh, PA; Cecilia W Lo, Univ of Pittsburgh, Pittsburgh, PA

3:00 PM

Board # 4048

Tricuspid Valve Regurgitation and Shunt Type in Association With Transplant-free Survival After Norwood: An Analysis of the Single Ventricle Reconstruction Trial Database

**Paul Joseph Devlin** , Northwestern Univ, Chicago, IL; Brian W McCrindle, HOSPITAL SICK CHILDREN, Toronto, ON, Canada; Kamal Pourmoghadam, Arnold Palmer Hosp For Children, Orlando, FL

3:00 PM

Board # 4049

Predictors for Seizures in Neonates Following Surgery With Cardiopulmonary Bypass

**Maryam Y Naim** , Shavonne L Massey, Andrew T Costarino, Stephanie Fuller, Childrens Hosp of Philadelphia, Philadelphia, PA; J. William Gaynor, J. William Gaynor, Philadelphia, PA; Stephen E Kimmel, Univ of Pennsylvania, Philadelphia, PA; Daniel J Licht, Childrens Hosp Philadelphia, Philadelphia, PA; Christopher E Mascio, Children's Hosp of Philadelphia, Philadelphia, PA; Susan C Nicolson, Children's Hosp of Philadelphia, Philadlephia, PA; Mary Putt, Univ of Pennsylvania, Philadelphia, PA; Nicholas S Abend, Childrens Hosp of Philadelphia, Philadelphia, PA

3:00 PM

Board # 4050

Cryopreserved Saphenous Vein Graft With External Stent as BT Shunt Conduit Allows Catheter Shunt Dilation as Prolonged Bridge to Second Surgery

**David M Hoganson** , Ryan Callahan, Breanna L Piekarski, Boston Children's Hosp, Boston, MA; Aditya K Kaza, BOSTON CHILDRENS HOSPITAL, Boston, MA; Sitaram Emani, Boston Children's Hosp, Boston, MA

3:00 PM

Poster Professor

Kristine J Guleserian, Miami, FL

# Abstract Poster Session

## SA.APS.12 - The "BASICS" of Heart Failure and Transplant

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 4323

Transcriptomic Analysis of the Human Heart Reveals Differential Response of Left and Right Ventricle During Cold Preservation With HTK Solution

Paul C Tang, **Ienglam Lei** , Univ of Michigan-Ann Arbor, Ann Arbor, MI

3:00 PM

Board # 4324

Mitochondrial and Cardiac Function Derangement in Donation After Circulatory Death Heart: Identifying Potential Targets to Modulate Reperfusion Injury

**Mohammed Quader** , VCU and McGuire Veterans Medical Ctr, Richmond, VA; Qun Chen, McGuire Veterans Hosp, Richmond, VA; Oluwatoyin Akande, VCU and McGuire Veterans Medial Ctr, Richmond, VA; Stefano Toldo, Virginia Commonwealth Univ, Glen Allen, VA; Edward J Lesnefsky, VCU and McGuire Veterans Medical Ctr, Richmond, VA

3:00 PM

Board # 4325

Long-Term Results of Autologous Skeletal Myoblast Cell-Sheet Transplantation for End-Stage Ischemic Cardiomyopathy

**Satoshi Kainuma** , Shigeru Miyagawa, Osaka Univ, Suita, Japan; Koichi Toda, Natl Cardiovascular Ctr, Kobe, Japan; Yasushi Yoshikawa, Osaka Univ, Suita Osaka, Japan; Hiroki Hata, Osaka Univ Graduate Sch of, Suita, Osaka, Japan; Daisuke Yoshioka, Osaka Univ, Suita, Japan; Takuji Kawamura, Osaka Univ, Osaka, Japan; Ai Kawamura, Osaka Univ, Suita-City, Osaka, Japan; Yoshiki Sawa, Osaka Univ, Osaka, Japan

3:00 PM

Board # 4327

Spatio-temporal Pattern Of Rv And Lv T-tubule Dysregulation In A Model Of Ischemic Heart Failure

**Michael Ibrahim** , Elizabeth Li, Univ of Pennsylvania, Philadelphia, PA; Ann Gaffey, Penn, Philadelphia; Samuel T Kim, Univ of Pennsylvania, Philadelphia, PA; Jennifer Chung, Hosp of the Univ of Penn, Philadelphia, PA; Pavan Atluri, Univ of Pennsylvania, Philadelphia, PA

3:00 PM

Board # 4328

Basal Left Ventricle Longitudinal Strain Predicts Survival After Surgical Ventricular Repair

**Olena Nemchyna** , Natalia Solowjowa, Michael Dandel, Yuriy Hrytsyna, Julia Stein, Sajjad Soltani, Jan Knierim, Felix Schönrath, Volkmar Falk, Christoph Knosalla, German Heart Ctr Berlin, Berlin, Germany

3:00 PM

Board # 4329

Quantifying Mitochondrial Injury With Varying Duration of Ischemia: Implications for Donation After Circulatory Death Organ Transplantation

**Qun Chen** , VCU, Richmond, VA; Oluwatoyin Akande, Virginia Commonwealth Univ, Richmond, VA; Stefano Toldo, VCU, Richmond, VA; Edward Joseph Lesnefsky, McGuire VA Medical Ctr, Richmond, VA; Mohammed Quader, VCU, Richmond, VA

3:00 PM

Board # 4330

Mesenchymal Stem Cells at the Time of Bypass Surgery Enhances Mitochondrial Biogenesis in Chronically Ischemic Heart Tissue

**Laura Hocum-Stone** , Christin Wright, Edward O Mcfalls, VA Medical Ctr Univ MN, Minneapolis, MN; Rosemary Frances Kelly, Univ of Minnesota, Minneapolis, MN

3:00 PM

Board # 4331

3d Net Mold System Derived Myocardial Block: Initial Feasibility and Effect of in situ Regeneration

**Takeyoshi Ota** , The Univ of Chicago, Chicago, IL; Keigo Kawaji, Austeja Staneviciute, Marcella Kae Vaicik, Illinois Inst of Technology, Chicago, IL; Andrew Beaser, Roderick Tung, The Univ of Chicago, Chicago, IL; Hiroshi Matsushita, Narutoshi Hibino, Johns Hopkins Hosp, Baltimore, MD; Takeyoshi Ota, The Univ of Chicago, Chicago, IL

3:00 PM

Board # 4332

Reducing Wall Stress With a Trans-Ventricular Restraint Improves Systolic Function and Cardiac Energy Metabolism in a Rodent Ischemic Cardiomyopathy Model

**Daisuke Onohara** , Daniella Corporan, Takanori Kono, Roberto Hernandez-Merlo, Muralidhar Padala, Emory Univ, Atlanta, GA

3:00 PM

Poster Professor

Pey-Jen Yu, Manhassaet, NY

# Abstract Poster Session

## SA.APS.09 - Thoracic Aortic Surgery/Disease II

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 4293

Time Of Day Does Not Influence Mortality In Patients Undergoing Surgical Repair Of Acute Type A Aortic Dissection

**George Arnaoutakis** , The Univ of Florida, Gainesville, FL; Christoph A Nienaber, The Royal Brompton & Harefield NHS Trust, London, United Kingdom; Anthony L Estrera, McGovern Medical Sch UT Health, Houston, TX; Derek Ralph Brinster, Northwell Health System, New York, NY; Marek P Ehrlich, Dept. Cardiothoracic Surgery, Vienna; Mark D Peterson, Univ of Toronto, Toronto, ON, Canada; Eduardo Bossone, Cava de' Tirreni and Amalfi Coast Hosp, Lauro, Italy; Truls Myrmel, Cava de' Tirreni and Amalfi Coast Hosp, Lauro, Italy, Norway; Davide Pacini, Cava de' Tirreni and Amalfi Coast Hosp, Lauro, Italy, Norway, Bologna, Italy; Daniel G Montgomery, Univ of Michigan, Ann Arbor, MI; Kim A Eagle, Univ Michigan, Ann Arbor, MI; Raffi Bekeredijan, Robert-Bosch Krankenhaus, Stuttgart, Germany; Sherene Shalhub, Univ of Washington, Seattle, WA; Carlo De Vincentiis, IRCCS Policlinico San Donato, San Donato, Italy; G Chad Hughes, Duke Univ Medical Ctr, Durham, NC; Edward P Chen, Hans-Henning Eckstein, EMORY UNIVERSITY, Atlanta, GA; Ibrahim Sultan, Univ of Pittsburgh, Pittsburgh, PA

3:00 PM

Board # 4294

Safety and Efficacy of Percutaneous Groin Access Closure vs. Surgical Cutdown for Thoracic Endovascular Aortic Repair and Transcatheter Aortic Valve Replacement: A Single-Center Retrospective Analysis

**Adam M. Carroll** , T. Brett Reece, Univ of Colorado, Aurora, CO; Christian V. Ghincea, Univ of Colorado, Denver, CO; Yuki Ikeno, Kaitlin Roth, Dominik M. Wiktor, Univ of Colorado, Aurora, CO; John C. Messenger, Univ of Colorado SOM, Aurora, CO; John D. Carroll, Joseph C. Cleveland, David A Fullerton, Muhammad Aftab, Univ of Colorado, Aurora, CO

3:00 PM

Board # 4295

Female Gender is Associated With Increased Risk of Stroke After Hemiarch Surgery

**Christian V. Ghincea** , Muhammad Aftab, Yuki Ikeno, Mohamed Eldeiry, Devon A. Anderson, Gavriel F. Roda, Jessica Rove, Jay D. Pal, Joseph C. Cleveland, David A Fullerton, T. Brett Reece, Univ of Colorado, Aurora, CO

3:00 PM

Board # 4296

The Decline of Beta Blocker Usage in Patients Admitted With Acute Type A Aortic Dissection

Carmel Ashur, Ann Arbor, MI; Madison Breeden, Univ of Michigan, Ann Arbor, MI; Linda Farhat, Univ of Michigan, Ann Arbor, MI, Ann Arbor, MI; Elizabeth Norton, Creighton Univ, Omaha, NE; James B Froehlich, Karen Kim, Shinichi Fukuhara, Michael G Deeb, Univ of Michigan, Ann Arbor, MI; Himanshu J Patel, Univ Michigan Health System, Ann Arbor, MI; Kim Eagle, Univ of Michigan; Bo Yang, **Marion A Hofmann Bowman** , Univ of Michigan, Ann Arbor, MI

3:00 PM

Board # 4297

Prognostic Prediction With Coagulative and Fibrinolytic Markers in Stanford Type a Acute Aortic Dissection

**Arima Daisuke** , Suematsu Yoshihhiro, Kurahashi Kanan, Shimizu Takaharu, Nishi Satoshi, Yoshimoto Akihiro, Morizumi Sei, Tsukuba Memorial Hosp, Tsukuba-shi, Japan

3:00 PM

Board # 4298

Zero Cerebral Circulatory Arrest Method of Selective Cerebral Perfusion for Type A Aortic Dissection Surgery Preventing Postoperative Cerebral Infarction

**Hiroaki Sakamoto** , Univ of Tsukuba, Tsukuba-shi, Japan; Hideyuki Kato, Muneaki Matsubara, Univ of Tsukuba, Tsukuba, Japan; Gomi Seigo, Yuichirou Kaminishi, Motoo Osaka, Univ of Tsukuba, Tsukuba-shi, Japan; Yuji Hiramatsu, Univ Tsukuba, Tsukuba, Japan

3:00 PM

Board # 4299

Clinical and Financial Implications of Refractory Hypertension in Acute Type B Aortic Dissection

**Xiaoying Lou** , Jake Rosen, Taylor A Melanson, William D Jordan Jr., Yazan Duwayri, Edward P Chen, Bradley G Leshnower, Emory Univ Sch of Med, Atlanta, GA

3:00 PM

Board # 4300

A Novel Risk Score on Admission for Predicting Death or Surgery in Patients With Acute Type a Intramural Hematoma Receiving Medical Therapy

**Shigetaka Kageyama** , Shizuoka City Shizuoka Hosp, Shizuoka, Japan

3:00 PM

Board # 4301

Risk Predictors of Moderate and Severe Aortic Stenosis in Patients With Bicuspid Aortic Valves

Thy Nguyen, Beth Israel Deaconess Medical Ctr, Boston, MA; **Chin Siang Ong** , Massachusetts General Hosp, Boston, MA; Xinling Xu, Beth Israel Deaconess Medical Ctr, Boston, MA; Jasmine Shahram, James L Gosnell, Salina Shrestha, J Daniel Muehlschlegel, Brigham and Women's Hosp, Boston, MA; BAV Consortium; Thoralf M Sundt, Massachusetts General Hosp, Boston, MA; Simon Christopher Body, Beth Israel Deaconess Medical Ctr, Boston, MA

3:00 PM

Board # 4302

Treatment of Aortic Valve Endocarditis With Stented or Stentless Valve: Short Term and Long Term Outcomes

**Bo Yang** , Jeffrey Clemence Jr, Linda Farhat, Bailey Brown, Emma St. Pierre, Tan D Le, Evelyn Gonzalez, Juan Caceres, Tom Ren, Alexander Makkinejad, Xiaoting Wu, Francis D Pagani, Jonathan Haft, Paul C TANG, Matthew A Romano, Richard L Prager, Steven F Bolling, Karen Kim, Himanshu J Patel, G. Michael Deeb, Univ of Michigan, Ann Arbor, MI

# Abstract Poster Session

## AT.APS.13 - Vascular and Valvular Calcification

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 1033

Impact of Serum 1,5-anhydro-d-glucitol Level on The Prediction of Severe Coronary Artery Calcification: An Intravascular Ultrasound Study

**Hideki Wada** , Juntendo Univ Shizuoka Hosp, Izunokuni Shizuoka, Japan; Tomotaka Dohi, Katsumi Miyauchi, Juntendo Univ, Tokyo, Japan; Norihito Takahashi, Juntendo Univ, Bunkyo-ku, Tokyo, Japan; Hirohisa Endo, Yoshiteru Kato, Juntendo Univ, Tokyo, Japan; Manabu Ogita, Juntendo Univ, Izunokuni, Japan; Iwao Okai, Juntendo Univ, Tokyo, Japan; Hiroshi Iwata, Juntendo Univ, Tokyo, MA, Japan; Shinya Okazaki, Kikuo Isoda, Kazunori Shimada, Juntendo Univ, Tokyo, Japan; Satoru Suwa, Juntendo Univ Shizuoka Hosp, Izunokuni, Japan; Hiroyuki Daida, Juntendo Univ, Tokyo, Japan

3:00 PM

Board # 1034

Effects of Surface Roughness on the Blood Flow in Calcified Arteries: A Fluid-Structure Interaction Model

**Gorg Abdelmassih** , Nina Kosciuszek, Gregory D. Oliva, NYIT Coll of Osteopathic Med, Old Westbury, NY; Dorinamaria Carka, NYIT Coll of Engineering and Computing Sciences, Old Westbury, NY; Olga V Savinova, NYIT Coll of Osteopathic Med, Old Westbury, NY

3:00 PM

Board # 1035

Aortic Valve Calcification and Subclinical Coronary Atherosclerosis in Japanese Heterozygous Familial Hypercholesterolemia Patients With High Lp(a) Levels

**Akiko Sakai** , Kayoko Sato, Haruki Sekiguchi, Michinobu Nagao, Shuji Sakai, Nobuhisa Hagiwara, Tokyo Women's Medical Univ, Tokyo, Japan

3:00 PM

Board # 1036

Hdl Mean Size is Associated With Coronary Artery Calcification, While Hdl-p and Its Subfractions Are Not

**Giuliano Generoso** , Heart Inst - USP, Sao Paulo, Brazil; Isabela M Bensenor, Hosp Univrio, Sao Paulo, Brazil; Raul Santos, Univ of Sao Paulo Medical Sch Hosp, S?o Paulo, Brazil; Itamar Souza Santos, Univ of Sao Paulo, Sao Paulo, Brazil; Steven R Jones, The Johns Hopkins Univ, Baltimore, MD; Michael J Blaha, Johns Hopkins Univ, Baltimore, MD; Peter P. Toth, CGH Medical Ctr, Sterling, IL; Paulo A Lotufo, Univ of Sao Paulo, Sao Paulo, Brazil; Marcio S Bittencourt, FICSAE, Sao Paulo, Brazil

3:00 PM

Board # 1037

Sirtuin 1 Prevents Age-associated Aortic Valve Calcification in vivo

**Zhejun Cai** , Jianfang Wang, Zhejiang Univ, Hangzhou, China; Ming Liu, Huazhong Univ Sch of Med, Wuhan, China; Tan Yuan, Zhejiang Univ, Hangzhou, China; Fei Li, Huazhong Univ Sch of Med, Wuhan, China

3:00 PM

Board # 1038

Activated Monocytes Elevate the Activity of Fibrocalcification in Human Aortic Valve Interstitial Cells via Paracrine Interaction

**Peijian Zhang** , Univ of Colorado Denver, Aurora, CO; Lihua Ao, Univ of Colorado, Aurora, CO; Dingli Xu, Nanfang Hosp, Guangzhou, China; David A Fullerton, Univ of Colorado, Aurora, CO; Xianzhong Meng, Univ Colorado Denver, Aurora, CO

3:00 PM

Board # 1039

Adoptive Transfer Studies Demonstrate T Cells Reactive to the Cationic Peptide Domain of the Cathelin-related Anti-Microbial Peptide Modulate Aortic Atherosclerosis and Plaque Calcification in ApoE-/- Mice

**Fernando Chernomordik** , Wai Man Lio, Juliana Yano, Xiaoning Zhao, Jianchang Zhou, Jonathan Ghermezi, Kuang-Yuh Chyu, Prediman K Shah, Bojan Cercek, Paul C Dimayuga, Cedars-Sinai Medical Ctr, Los Angeles, CA

3:00 PM

Board # 1040

Effects of Long-Term Endurance Exercise on Calcific Atherosclerotic Plaque Microarchitecture

**Jeffrey J Hsu** , Felicia Fong, UCLA, Los Angeles, CA; Radha Nilesh Patel, Univ of California Los Angele, Los Angeles, CA; Rong Qiao, Karen Lo, Akrivoula Soundia, Chih-Chiang Chang, Victoria Le, UCLA, Los Angeles, CA; Tzung K Hsiai, UCLA Sch of Med Cardiology Div, Los Angeles, CA; Linda L Demer, UCLA Sch Med Cardiology, Los Angeles, CA; Yin Tintut, UCLA Sch of Med, Los Angeles, CA

3:00 PM

Board # 1041

Cellular Contraction is Required for Hyperglycemia-Induced Vascular Calcification

**Hooi Hooi Ng** , Daniela Medina, Amirala Bakhshian Nik, Joshua D Hutcheson, Florida Intl Univ, Miami, FL

3:00 PM

Board # 1042

Repression of Age-Determined Vascular Calcification by Ectonucleotidase CD73

**Nadia R Sutton** , Judy Kim, Rachel Kroll, Jun Chen, Univ Michigan, Ann Arbor, MI; David J Pinsky, Univ Michigan Internal Med, Ann Arbor, MI

3:00 PM

Poster Professor

Yucheng Yao, Los Angeles, CA

# Abstract Poster Session

## AT.APS.15 - Vascular Differentiation and Regeneration I

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 1055

Insulin-Like Growth Factor Binding Protein 2 Overexpression Leads to Aortic Hypocontractility Through Vascular Smooth Muscle Phenotypic Switching

**Thomas Slater** , Alexander-Francisco Bruns, Natalie Haywood, Mohammed Abdul Waduud, Karen Hemmings, Katherine Bridge, Asjad Visnagri, Andrew Walker, Michael Drozd, Marc Bailey, Nadira Y Yuldasheva, Karen E Porter, Richard Cubbon, Mark Kearney, Stephen B Wheatcroft, Univ of Leeds, Leeds, United Kingdom

3:00 PM

Board # 1056

**Generation of Quiescent Cardiac Fibroblasts From Human Induced Pluripotent Stem Cells for i** n vitro **Modeling of Cardiac Fibrosis**

**Hao Zhang** , Lei Tian, Mengcheng Shen, Chengyi Tu, Haodi Wu, Mingxia Gu, Stanford Univ, Stanford, CA; David T Paik, Stanford Univ, Palo Alto, CA; Joseph C Wu, Stanford Univ, Stanford, CA

3:00 PM

Board # 1057

Cathepsin K Controls Injury-related Neointimal Formation in Mice Under Chronic Stress via the Modulation of Inflammation and Immune Action

**Xiangkun Meng** , Limei Piao, Nagoya Univ Graduate Sch of Med, Nagoya, Japan; Hailong Wang, Yanbian Univ Hosp, Yanji, China; Aiko Inoue, Nagoya Univ Graduate Sch of Med, Nagoya, Japan; Toyoaki Murohara, Cardiology, Nagoya Univ, Nagoya, Japan; Guo-Ping Shi, Brigham Womens Hosp, Boston, MA; Masafumi Kuzuya, Nagoya Univ Sch of Medicin, Nagoya, Japan; Xian Wu Cheng, Yanbian Univ Hosp, Yanji, China

3:00 PM

Board # 1058

**Increased Oxidative Stress and Decreased Mitochondrial Energy Metabolism and Skeletal Muscle Myogenesis Genes in an** in vitro **Model of Peripheral Artery Disease Myopathy**

Ahmed Ismaeel, Evlampia Papoutsi, Florida State Univ, Tallahassee, FL; Ian Sawicki, William T Bohannon, Robert S Smith, Baylor Scott and White Hosp, Temple, TX; **Panagiotis Koutakis** , Florida State Univ, Tallahassee, FL

3:00 PM

Board # 1059

Adiponectin and the Regulation of Vascular Smooth Muscle Cell Phenotype

**Abigail Cullen** , Ahmed Ismaeel, Panagiotis Koutakis, Gloria Salazar, Florida State Univ, Tallahassee, FL

3:00 PM

Board # 1060

Involvement of FoxO1 in Vascular Remodeling of Diabetic Rats

**Jingjin Liu** , Univ of Hong Kong, Hong Kong, Hong Kong; Zhengyuan Xia, The Univ of Hong Kong, Hong Kong, Hong Kong

3:00 PM

Board # 1061

Monocyte Derived Cleaved Dll4 Inhibits Notch1 Activation in Endothelial Cell and Promotes Pulmonary Arterial Hypertension Progression

**Shumin Wang** , Univ of Rochester Medical Ctr, Rochester, NY

3:00 PM

Board # 1063

Estrogen-Related Receptor Alpha Promotes Therapeutic Angiogenesis in Murine Model of Peripheral Artery Disease

**Danesh H Sopariwala** , Neah Likhite, Ctr for Metabolic and Degenerative Diseases, Brown Fndn Inst of Molecular Med, McGovern Medical Sch, Univ of Texas Health Science Ctr at Houston, Houston, TX; Vihang A Narkar, Ctr for Metabolic and Degenerative Diseases, Brown Fndn Inst of Molecular Med, McGovern Medical Sch, Univ of Texas Health Science Ctr in Houston, and Univ of Texas Graduate Sch of Biomedical Sciences, Houston, TX

3:00 PM

Poster Professor

Isabella M Grumbach, Iowa City, IA

3:00 PM

Board # 1064

Phosphorylation Regulates the Functions of Kindlin-3 in Hematopoietic and Non-hematopoietic Cells

**Katarzyna Bialkowska** , Cleveland Clinic, Cleveland, OH; Khalid Sossey-Alaoui, Case Western Reserve Univ Sch of Med, Cleveland, OH; Elzbieta Pluskota, Lahoucine Izem, Dorota Szpak, Jun Qin, Edward F Plow, Cleveland Clinic, Cleveland, OH

3:00 PM

Board # 1065

Vegf-b Promotes Endocardial Reprogramming For Coronary Revascularization

**Markus Otto Hjalmar Rasanen** , Paech Jennifer, Karthik Amudhala Hemanthakumar, Ibrahim Sultan, Wihuri Res Inst, Helsinki, Finland; Wei Yu, The State Key Lab of Cell Biology, Shanghai, China; Liqun He, Dept of Immunology, Uppsala, Sweden; Juan Tang, The State Key Lab of Cell Biology, Helsinki, Finland; Ying Sun, Dept of Immunology, Uppsala, Sweden; Ruslan Hlushchuk, Oleksiy-Zakhar Khoma, Inst of Anatomy, Bern, Switzerland; Eero Ma Mervaala, Univ of Helsinki, Helsinki, Finland; Valentin Djonov, Inst of Anatomy, Bern, Switzerland; Christer Betsholtz, ICMC (Integrated Cardio Metabolic Ctr), Stockholm, Sweden; Riikka Kivelä, Wihuri Res Inst, Helsinki, Finland; Bin Zhou, Shanghai Insts for Biological, Shanghai; Kari Kustaa Alitalo, Univ Helsinki, Helsinki, Finland

# Abstract Poster Session

## AT.APS.14 - Vascular Inflammation and Aortic Aneurysm

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 1043

Maternal High-fat Diet Promotes the Expansion of Abdominal Aortic Aneurysm in Adult Offspring by Skewing of Macrophage Differentiation Toward Osteoclast-like Macrophages

**Makoto Saburi** , Hiroyuki Yamada, Kyoto Prefectural Univ of Med, Kyoto City, Japan; Sugimoto Takeshi, Kyoto Prefectural Univ of Med, Kyoto, Japan; Hiroshi Kubota, Daisuke Miyawaki, Kyoto Prefectural Univ of Med, Kyoto City, Japan; Noriyuki Wakana, Satoaki Matoba, Kyoto Prefectural Univ of Med, Kyoto, Japan

3:00 PM

Poster Professor

Bo Liu, Madison, WI

3:00 PM

Board # 1044

Macrophages and T Cells Differentially Regulate Abdominal Aortic Aneurysm in Interleukin-12p40 Deficient Apolipoprotein E-knockout Mice

**Neekun Sharma** , Chetan P Hans, Univ of Missouri, Columbia, MO

3:00 PM

Board # 1045

SDPR/Cavin-2 in Endothelial Cells Contributes to Inflammatory Cell Adhesion in Abdominal Aortic Aneurysm

**Akira Sakamoto** , Takehiro Ogata, Naohiko Nakanishi, Yusuke Higuchi, Yumika Tsuji, Shinya Tomita, Satoaki Matoba, Kyoto Prefectural Univ of Med, Kyoto, Japan

3:00 PM

Board # 1046

Moderate Aerobic Exercise Reduces Aortic Wall Remodeling, Aneurysm Formation, and Mortality in a Mouse Model of Beta-Aminopropionitrile-Induced Aortic Disease

Brittany O Aicher, Selen C Muratoglu, Rebeca Galisteo, Allison Arai, Univ of Maryland Sch of Med, Baltimore, MD; Vicki L Gray, Univ of Maryland Baltimore, Baltimore, MD; Brajesh Lal, Univ of Maryland Sch of Med, Baltimore, MD; Dudley Strickland, Univ of Maryland Baltimore, Baltimore, MD; **Areck A Ucuzian** , Univ of Maryland Sch of Med, Baltimore, MD

3:00 PM

Board # 1047

Soluble Epoxide Hydrolase Inhibition Attenuates Abdominal Aortic Aneurysm Formation: Potential Mechanisms Linking Liver to Aneurysm Pathogenesis

**Tetsuo Horimatsu** , Tyler W Benson, Mary Moses, Medical Coll of Georgia at Augusta Univ, Augusta, GA; Neal L Weintraub, Augusta Univ, Augusta, GA; Ha Won Kim, Medical Coll of Georgia, Augusta, GA; David Kim, Medical Coll of Georgia at Augusta Univ, Augusta, GA

3:00 PM

Board # 1048

Osteoprotegerin is Co-Localized With Versican, and Plays a Role in Maintaining the Structural Integrity in Aorta

**Toshihiro Tsuruda** , Univ Miyazak, Miyazaki, Japan; Atsushi Yamashita, Miyazaki Univ, Miyazaki, Japan; Kinta Hatakeyama, Nara Medical Univ, Kashihara, Japan; Yujiro Asada, Univ Miyazak, Miyazaki, Japan; Kazuo Kitamura, Univ Miyazak, Miyazaki City, Japan

3:00 PM

Board # 1049

Deletion of the Duffy Antigen Receptor for Chemokines Confers Protection Against Abdominal Aortic Aneurysm Formation

**Tyler W Benson** , Medical Coll of Georgia at Augusta Univ, Augusta, GA; Tetsuo Horimatsu, Medical Coll of Gerogia, Augusta, GA; Ha Won Kim, Medical Coll of Georgia, Augusta, GA; Neal L Weintraub, Augusta Univ, Augusta, GA

3:00 PM

Board # 1050

A Theranostic Role for C-C Chemokine Receptor 2 in the Management of Rodent Abdominal Aortic Aneurysm Development and Rupture

**Sergio E Sastriques** , Lisa M Detering, Deborah H Sultan, Hannah P Luehmann, Batool Arif, Robert J Gropler, Chieh-Yu Lin, Jie Zheng, Yongjian Liu, Sean J English, Washington Univ Sch of Med, Saint Louis, MO

3:00 PM

Board # 1051

Biomimetic Scaffolds Composed of Human Induced Pluripotent Smooth Muscle Progenitor Cells for Treatment of Murine Abdominal Aortic Aneurysm

**Ngan F Huang** , Stanford Univ, Stanford, CA; Joscha Udo Nikolaus Mulorz, Stanford Univ, Cardiovasc Med, Stanford, CA; Cynthia Alcazar, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA; Caroline Hu, Veterans Affairs Palo Alto Heatlh Care System, Palo Alto, CA; Mahdis Shayan, Yan Wen, Stanford Univ, Stanford, CA; Joshua Spin, Stanford Univ, Palo Alto, CA; Bertha Chen, Philip S Tsao, Stanford Univ, Stanford, CA

3:00 PM

Board # 1052

**Repeated Social Defeat Exaggerates CaCl** 2 **-Induced Abdominal Aortic Aneurysm Expansion by Eliminating Periaortic Fibrosis in Tissue Repair Phase**

**Hiroshi Kubota** , Kyoto Prefectural Univ of Med, Kyoto, Japan; Hiroyuki Yamada, Kyoto Prefectural Univ. of Med, Kyoto, Japan; Takeshi Sugimoto, Daisuke Miyawaki, Kyoto Prefectural Univ of Med, Kyoto, Japan; Makoto Saburi, Kyoto Prefectural Univ of Med, Kyoto City, Japan; Noriyuki Wakana, Satoaki Matoba, Kyoto Prefectural Univ of Med, Kyoto, Japan

3:00 PM

Board # 1053

Prolonged T Cell Dysfunction After Elective Cardiac Surgery

**Da Liu** , Univ of Pennsylvania, Philadelphia, PA; Maria Mukhanova, Drexel Univ, Philadelphia, PA; Jihane Hajj, Widener Univ, Chester, PA; Matthew DiMeglio, Philadelphia Coll of Osteopathic Med, Philadelphia, PA; Krzysztof Laudanski, Hosp of the Univ of Pennsylvania, Philadelphia, PA; Karima Rai, Drexel Univ, Philadelphia, PA

3:00 PM

Board # 1054

PCSK9 Knockdown Decreases Inflammatory Markers and U937 Monocyte Accumulation in a Tissue-Engineered Blood Vessel Model

**Jason J Breithaupt** , Duke Univ, Durham, NC; Jennifer Kwon, Duke Univ, Durhm, NC; Adarsh Ettyreddy, Xu Zhang, Charles Gersbach, Duke Univ, Durham, NC; George A Truskey, Duke Univ Biomed Engineering, Durham, NC

# Best of AHA Specialty Conferences

## BASC.02 - Best of AHA Specialty Conferences: BCVS 2019

#### Best of Specialty Conferences, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 123

Osteopontin Regulates Adult Cardiomyocyte Division in a Mouse Model of Pressure Overload Induced Heart Failure

**Camila Iansen Irion** , Krista John-Williams, Ahmed Chahdi, Keyvan Yousefi, Yanelys R. Fernandez, Konstantinos E. Hatzistergos, Joshua M. Hare, Keith Webster, Lina A. Shehadeh, Univ of Miami, Miami, FL

3:00 PM

Board # 124

Identification of Novel MICU1 Interactors Independent of the mtCU Complex

**Dhanendra Tomar** , Joanne F Garbincius, Devin Kolmetzky, Manfred Thomas, Pooja Jadiya, John W Elrod, Temple Univ, Philadelphia, PA

3:00 PM

Board # 125

Synergistic Activation of the Cardiac Enhancer Landscape During Cardiac Reprogramming

**Glynnis A Garry** , Hisayuki Hashimoto, Zhaoning Wang, Huanyu Zhou, Ning Liu, Rhonda Bassel-Duby, Eric N Olson, UT Southwestern Medical Ctr, Dallas, TX

3:00 PM

Board # 126

Primary Cilia of the Cardiac Neural Crest Orchestrate Critical Aspects of Ventricular Maturation and Postnatal Cardiac Function: A Role for Hedgehog Signaling

**Lindsey A Fitzsimons** , Univ of New England, Coll of Osteopathic Med, Biddeford, ME; Adrian M Moran, Dept of Pediatric Cardiology, Maine Medical Ctr, Portland, ME; Kerry L Tucker, Coll of Osteopathic Med, Univ of New England, Biddeford, ME

3:00 PM

Board # 127

**Selective i** n vivo **Modulation of Vagal-Muscarinic Signaling Prevents Sudden Cardiac Death in a Pressure Overload Model of Heart Failure**

**Jeffrey S Crocker** , Daiana C. O. Vieira, Kenneth G. Parks, Div of Cardiology and of Pharmacology and Systems Physiology, Univ of Cincinnati Coll of Med, Cincinnati, OH; Brian O'Rourke, Swati Dey, Div of Cardiology, Johns Hopkins Univ Sch of Med, Baltimore, MD; Deeptankar DeMazumder, Div of Cardiology and of Pharmacology and Systems Physiology and of The Artificial Intelligence Ctr of Excellence, Univ of Cincinnati Coll of Med, Cincinnati, OH

3:00 PM

Board # 128

Molecular, Cellular and Systemic Mechanism of Nonlinear Dynamic Patterns of Ventricular Repolarization and Spontaneous Arrhythmic Sudden Death in Non-ischemic Heart Failure

**Daiana C. O. Vieira** , Jeffrey S Crocker, Krina Desai, Neha Reddy Sanagala, Daniel R Wendelken, Kenneth G Parks, Div of Cardiology, Univ of Cincinnati Coll of Med, Cincinnati, OH; Ting Liu, Brian O'Rourke, Swati Dey, Div of Cardiology, Johns Hopkins Univ Sch of Med, Baltimore, MD; Deeptankar DeMazumder, Div of Cardiology, Univ of Cincinnati Coll of Med, Cincinnati, OH

3:00 PM

Board # 129

Profiling Differential Response to Myocardial Infarction by Single Cell Analysis of the Cardiac Interstitium

**Elvira Forte** , The Jackson Lab, Bar Harbor, ME

3:00 PM

Board # 130

Downregulation of the Cardiac Sodium Channel Nav1.5 Mediates Obesity-Induced Atrial Fibrillation

**Arvind Sridhar** , Mark McCauley, Liang Hong, Ambili Menon, Meihong Zhang, Univ of Illinois, Chicago, Chicago, IL; JiaJie Yan, Rush Univ, Chicago, IL; Seock-Won Youn, Ivson Bezerra da Silva, Marcelo Bonini, Jalees Rehman, Dawood Darbar, Univ of Illinois, Chicago, Chicago, IL

3:00 PM

Board # 131

Trpv4 Deletion in Endothelium Protects Heart Against Pressure Overload Induced Hypertrophy

Ravi K Adapala, Anantha K Kanugula, Vahagn Ohanyan, Nina Lenkey, North East Ohio Medical Univ, Rootstown, OH; Sailaja Paruchuri, Univ of Akron, Akron, OH; William M Chilian, **Charles K Thodeti** , North East Ohio Medical Univ, Rootstown, OH

3:00 PM

Board # 133

Aberrant Activation of Nitric Oxide Synthase 1 in the Heart Accelerates Diastolic Dysfunction Though Protein S-nitrosylation

**Somy Yoon** , Mira Kim, Chonnam Natl Univ, Jeollanam-do, Korea, Republic of; Yongsook Kim, Youngkeun Ahn, Chonnam Natl Univ Hosp, Gwangju, Korea, Republic of; Hyun Kook, Gwang Hyeon Eom, Chonnam Natl Univ, Jeollanam-do, Korea, Republic of

3:00 PM

Board # 134

**Experimental Verification of Value of T** peak **-T** end **Interval in Ventricular Arrhythmia Inducibility in Early Repolarization Syndrome Model**

**Namsik Yoon** , Seo Na Hong, Hyung Ki Jeong, Ki Hong Lee, Hyung Wook Park, Jeong Gwan Cho, Chonnam Natl Univ Hosp, Gwangju, Korea, Republic of

3:00 PM

Board # 135

**Celltype-Specific Functions in Dilated Cardiomyopathy Caused by the** LMNA **Gene Mutation**

Kunal Sikder, Elizabeth Phillips, Zhijiu Zhong, Nadan Wang, Thomas Jefferson Univ, Philadelphia, PA; Kenneth B Margulies, Univ at Pennsylvania, Philadelphia, PA; **Jason C Choi** , Thomas Jefferson Univ, Philadelphia, PA

3:00 PM

Board # 136

Human Neonatal Cardiac Progenitor Cells Derived Exosomes Induce Cardiomyocytes Proliferation

**Sudhish Sharma** , Lina Wang, Chetan Ambastha, Rachana Mishra, Sunjay Kaushal, Univ of Maryland, Baltimore, MD

3:00 PM

Board # 137

Mutual Potentiation Between Myofibril Assembly and Serum Response Factor in Cardiomyocyte Maturation

**Yuxuan Guo** , Blake Jardin, Isha Sethi, Behzad Moghadaszadeh, Alan Beggs, William Pu, Boston Children's Hosp, Boston, MA

3:00 PM

Board # 138

Understanding Cardiomyocyte Mechanosensing Utilizing CRISPR-Cas9 Based Screening Methods

**Feria Ladha** , Anthony Pettinato, Univ of Connecticut Sch of Med, Farmington, CT; Ketan Thakar, The Jackson Lab for Genomic Med, Farmington, CT; J. T. Hinson, Univ of Connecticut Sch of Med, Farmington, CT

3:00 PM

Board # 139

Dual Activation of PKA and PKG by PDE1 Inhibition Facilitates Proteasomal Degradation of Misfolded Proteins and Protects Against Proteinopathy-Based HFpEF

Hanming Zhang, Bo Pan, Penglong Wu, Univ South Dakota, Vermillion, SD; Mark D Rekhter, Lilly Res Labs, Indianapolis, IN; Alfred L Goldberg, Harvard Medical Sch, Boston, MA; **Xuejun Wang** , Univ South Dakota, Vermillion, SD

3:00 PM

Board # 140

Pharmacologic Characterization of the Cardiac Myosin Inhibitor, CK-3773274: A Potential Therapeutic Approach for Hypertrophic Cardiomyopathy

**Darren T Hwee** , James J. Hartman, Jingying Wang, Yangsong Wu, Julia Schaletzky, Preeti Paliwal, Ken Lee, Khanha D Taheri, Eddie Wehri, Chihyuan Chuang, Bradley P Morgan, Fady I Malik, Eva R. Chin, Cytokinetics, Inc., South San Francisco, CA

3:00 PM

Board # 141

**Modeling Congenital Heart Disease-Associated Variants in** GATA6 **Using CRISPR/Cas9 and Human Induced Pluripotent Stem Cells**

**Arun Sharma** , Lauren Wasson, Jon Willcox, Sarah U Morton, Joshua M Gorham, Daniel M DeLaughter, Meraj Neyazi, Manuel Schmid, Radhika Agarwal, Megan Jang, Christopher N Toepfer, Tarsha Ward, Yuri Kim, Alexandre C Pereira, Steven R DePalma, Angela Tai, Seongwon Kim, David Conner, Harvard Medical Sch, Cambridge, MA; Benoit Bruneau, Gladstone Insts, San Francisco, CA; Jon G Seidman, Christine E Seidman, Harvard Medical Sch, Cambridge, MA

3:00 PM

Board # 142

Cardiomyocyte Maturation and Multinucleation in Postnatal Swine

**Nivedhitha Velayutham** , Christina M Alfieri, Emma J Agnew, Kyle W Riggs, Richard S Baker, Farhan Zafar, Katherine E Yutzey, Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH

3:00 PM

Board # 143

Pharmacological Evaluation of Novel Anti-thrombospondin-1 Decoy Strategy for Prophylaxis of Atrial Fibrillation-associated Ischemic Stroke

Tamer Elbayoumi, Midwestern Univ, Glendale, AZ; Jalicia Sturdivant, Midwestern Univ-AZCOM, Glendale, AZ; Samayita Ganguly, Midwestern Univ-CPG, Glendale, AZ; **Mingyi Yao** , Midwestern Univ, Glendale, AZ

3:00 PM

Board # 144

Comprehensive Arteriovenous Metabolomics in the Human Heart

**Danielle S Murashige** , Univ of Pennsylvania, Philadelphia, PA; Cholsoon Jang, Princeton Univ, Princeton, NJ; Michael D Neinast, Univ of Pennsylvania, Philadelphia, PA; John W Elrod, Temple Univ, Philadelphia, PA; Daniel P Kelly, Univ of Pennsylvania, Philadelphia, PA; Joshua D Rabinowitz, Princeton Univ, Princeton, NJ; David S Frankel, Zoltan P Arany, Univ of Pennsylvania, Philadelphia, PA

3:00 PM

Board # 145

Nicotinamide Riboside Modulates Late Sodium Current and Cardiac Repolarization

**Daniel S Matasic** , Pravda Quinones, Charles Brenner, Barry London, The Univ of Iowa, Iowa City, IA

3:00 PM

Board # 146

Spatiotemporal Dynamics of Macrophages in vitro and in vivo

**Nika Taghdiri** , Kenneth Mark Huang, Univ of California, San Diego, La Jolla, CA; Rainer H. Kohler, Ralph Weissleder, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Kevin R King, Univ of California, San Diego, La Jolla, CA

3:00 PM

Board # 147

Isolation & Characterization of Heart-field Specific Cardiomyocytes

**Arash Pezhouman** , James L Engel, Ngoc B Nguyen, Rhys JP Skelton, Peng Zhao, Blake W Gilmore, Nicholas Hornstein, Reza Ardehali, ucla, Los Angeles, CA

3:00 PM

Board # 148

**Wnt Signaling Inhibition Rescues Voltage-Gated Na** + **Current in Brugada Syndrome Patient Cardiomyocytes**

**Wenbin Liang** , Aizhu Lu, Cencen Chu, Jerry Wang, Univ. of Ottawa Heart Inst, Ottawa, ON, Canada

3:00 PM

Board # 149

**Reduced Cardiac Transmembrane Protein 65 Resulted in Dilated Cardiomyopathy and Progressive Cardiac Fibrosis** in vivo

**Allen C.T. Teng** , Ted Rogers Ctr for Heart Res, Toronto, ON, Canada; Liyang Gu, Translational Biology and Engineering Program, TRCHR, Toronto, ON, Canada; Michelle Di Paola, Univ of Toronto, Toronto, ON, Canada; Meena Fatah, Diptendu Chatterjee, The Hosp for Sick Children & Res Inst, Toronto, ON, Canada; Thomas Kislinger, Princess Margaret Cancer Ctr, Toronto, ON, Canada; Robert Hamilton, The Hosp for Sick Children & Res Inst, Toronto, ON, Canada; Anthony O. Gramolini, Univ of Toronto, Toronto, ON, Canada

3:00 PM

Board # 150

Surgical Bilateral Stellate Ganglionectomy Reduces Mitochondrial Reactive Oxygen Species (mROS) and Prevents Sudden Cardiac Death (SCD) in Non-ischemic Heart Failure (HF)

**Swati Dey** , Vanderbilt Univ Medical Ctr, Nashville, TN; Brian O'Rourke, Johns Hopkins Univ, Baltimore, MD; Deeptankar DeMazumder, Div of Cardiology and of Pharmacology and Systems Physiology, Univ of Cincinnati Coll of Med, Cincinnati, OH

3:00 PM

Board # 151

Activation of Transient Receptor Potential Canonical Channel Currents in Iron-Overloaded Cardiac Myocytes

Natthaphat Siri-Angkul, Richard Gordan, Rutgers-New Jersey Medical Sch, Newark, NJ; Suwakon Wongjaikam, Chiang Mai Univ, Chiang Mai, Thailand; Nadezhda Fefelova, Judith Gwathmey, Rutgers-New Jersey Medical Sch, Newark, NJ; Siriporn Chattipakorn, Nipon Chattipakorn, Chiang Mai Univ, Chiang Mai, Thailand; **Lai-Hua Xie** , Rutgers-New Jersey Medical Sch, Newark, NJ

3:00 PM

Board # 152

Inhibition of Long Noncoding RNA lncExACT1 Induces Physiological Cardiac Hypertrophy and Protects Against Pathological Hypertrophy

**Haobo LI** , Xiaojun Liu, Chunyang Xiao, Guoping Li, Ashish Yeri, Anthony Rosenzweig, Corrigan-Minehan Heart Ctr and Cardiology Div, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA

3:00 PM

Board # 153

Length Dependent Activation in Porcine Cardiac Myofilaments is Modulated by Mavacamten

Marcus Henze, Myokardia Inc, South San Francisco, CA; Weikang Ma, Illinois Inst of Technology, Chicago, IL; Fiona Wong, Myokardia Inc, South San Francisco, CA; Henry Gong, Illinois Inst of Technology, Chicago, IL; Robert Anderson, Carlos del Rio, Myokardia Inc, South San Francisco, CA; **Thomas Charles Irving** , Illinois Inst of Technology, Chicago, IL

3:00 PM

Board # 154

Single-nucleus Transcriptome Analysis of Patients' Heart Tissue Reveals Disease-specific Transcriptional Signatures in Heart Failure

**Kanna Fujita** , Seitaro Nomura, The Univ of Tokyo, Bunkyo, Tokyo, Japan; Takanori Fujita, Res Ctr for Advanced Science and Technology, the Univ of Tokyo, Meguro, Tokyo, Japan; Masahiro Satoh, Res Ctr for Advanced Science and Technology, the Univ of Tokyo, Megurp, Tokyo, Japan; Toshiyuki Ko, Shintaro Yamada, Masamichi Ito, The Univ of Tokyo, Bunkyo, Tokyo, Japan; Manami Katoh, Res Ctr for Advanced Science and Technology, the Univ of Tokyo, Megurp, Tokyo, Japan; Masaru Hatano, The Univ of Tokyo, Bunkyo, Tokyo, Japan; Hiroyuki Aburatani, Res Ctr for Advanced Science and Technology, the Univ of Tokyo, Meguro, Tokyo, Japan; Issei Komuro, The Univ of Tokyo, Bunkyo, Tokyo, Japan

3:00 PM

Board # 155

Reversible Cardiac Action Potential Recordings to Track Cellular Electrophysiology Over Days

Viviana Zlochiver, Stacie Edwards, Jonathan A. Cook, Aurora Res Inst, Milwaukee, WI; **Rosy Joshi-Mukherjee** , Johns Hopkins Univ, Baltimore, MD

3:00 PM

Board # 156

Multi-Omics Investigation of Cardiomyocyte-to-Fibroblast Crosstalk in Human iPSC Models

**Edward Lau** , Mark J Chandy, Damon R Williams, Rajani Shrestha, June-Wha Rhee, Joseph C Wu, Stanford Univ, Palo Alto, CA

3:00 PM

Board # 157

Cardioprotective Effects of Brain-derived Neurotrophic Factor rs6265 Polymorphism in Duchenne Cardiomyopathy

**Frank J Raucci Jr.** , Anand P. Singh, Jonathan H. Soslow, Lin Zhong, Wejdan Aljafar, Natasja Lessiohadi, Cassandra P. Awgulewitsch, Prachi Umbarkar, Qinkun Zhang, Holly M. Smith, Presley L. Cannon, Erica J. Carrier, Antonis K. Hatzopoulos, Hind Lal, Cristi L. Galindo, Vanderbilt Univ Medical Ctr, Nashville, TN

3:00 PM

Board # 158

Inhibition of Autosis Attenuates Ischemia/reperfusion Injury in the Heart

**Gihoon NAH** , Rutgers Univ NJMS, Newark, NJ; Alvaro Fernandez, Univ of Texas Southwestern Medical Ctr, Dallas, TX; Peiyong Zhai, Rutgers Univ NJMS, Newark, NJ; Beth Levine, Univ of Texas Southwestern Medical Ctr, Dallas, TX; Junichi Sadoshima, Rutgers Univ NJMS, Newark, NJ

3:00 PM

Board # 159

Reduced Expression of the Cardiac Sodium Channel Nav1.5 Triggers Enhanced Fatty Acid Metabolism and Oxidative Stress

**Ryan L Boudreau** , Xiaoming Zhang, Jared M McLendon, William Kutschke, Ethan J Anderson, Barry London, Univ of Iowa, Iowa City, IA

3:00 PM

Board # 160

Biphasic Reprogramming of Ventricular Cardiomyocytes to Pacemaker Cells by Tbx18

**Jinqi Fan** , Natasha Fernandez, Hee Cheol Cho, Emory Univ, Atlanta, GA

# Best of AHA Specialty Conferences

## BASC.04 - Best of AHA Specialty Conferences: EPI/Lifestyle 2019

#### Best of Specialty Conferences, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 189

The Role of Aspirin in the Relationship Between Hypertensive Disorders of Pregnancy and Incident Maternal Cardiovascular Disease

**Jennifer J Stuart** , Lauren J Tanz, Janet W Rich-Edwards, Brigham and Women's Hosp, Boston, MA; Eric B Rimm, Harvard T.H. Chan Sch of Public Health, Boston, MA; Kenneth J Mukamal, Beth Israel Deaconess Medical Ctr, Boston, MA; Gary C. Curhan, Kathryn M Rexrode, Brigham and Women's Hosp, Boston, MA

3:00 PM

Board # 190

Women Experience Higher Rates of Surgical Repair and Mortality for Abdominal Aortic Aneurysm

**Niveditta Ramkumar** , The Dartmouth Inst, Lebanon, NH; Bjoern D Suckow, Dartmouth Hitchcock Medical Ctr, Lebanon, NH; Art Sedrakyan, Weill Cornell Medical Coll, New York, NY; Philip P Goodney, Dartmouth Hitchcock Medical Ctr, Lebanon, NH; Jeremiah R Brown, The Dartmouth Inst, Lebanon, NH

3:00 PM

Board # 191

Changes in Gut Microbial Metabolites and Risk of Coronary Heart Disease in US Women: the Nurses' Health Study

**Yoriko Heianza** , Tulane Univ, New Orleans, LA; Wenjie Ma, Harvard T.H. Chan Sch of Public Health, Boston, MA; Joseph A. DiDonato, Cleveland Clinic, Cleveland, OH; Qi Sun, Eric B. Rimm, Frank B. Hu, Harvard T.H. Chan Sch of Public Health, Boston, MA; Kathryn M. Rexrode, Brigham and Women's Hosp and Harvard Medical Sch, Boston, MA; JoAnn E. Manson, Harvard T.H. Chan Sch of Public Health; Brigham and Women's Hosp and Harvard Medical Sch, Boston, MA; Lu Qi, Harvard T.H. Chan Sch of Public Health; Tulane Univ, New Orleans, LA

3:00 PM

Board # 192

Association of Physical Inactivity and Lifetime Risk of Heart Failure Among White and Black US Adults

**Sadiya S Khan** , Amanda E. Paluch, Hongyan Ning, Northwestern Univ, Chicago, IL; Jarett D. Berry, UT Southwestern, Dallas, TX; Mercedes Carnethon, John T. Wilkins, Donald M. Lloyd-Jones, Northwestern Univ, Chicago, IL

3:00 PM

Board # 193

The Dose-Response Effect of a Mediterranean Style Diet With Lean Beef on Lipids and Lipoproteins

**Jennifer Fleming** , Penny Kris-Etherton, Kristina Petersen, Penn State Univ, University Park, PA; David Baer, USDA, Beltsville, MD

3:00 PM

Board # 194

Higher Fitness Level and Favorable Hemodynamic Responses to Submaximal Exercise Test in Young Adults are Associated With Lower Risk of Chronic Kidney Disease in Later Life: The Framingham Heart Study

**Joowon Lee** , Vanessa Xanthikis, Boston Univ Sch of Med, Boston, MA; Rebecca Song, Boston Univ Sch of Public Health, Boston, MA; Ramachandran S Vasan, Boston Univ Sch of Med, Boston, MA

3:00 PM

Board # 195

Lower Levels of County Housing Affordability Are Linked to Worse Cardiometabolic Risk Profiles in Middle-Aged and Older Adults

**Justin Rodgers** , Northeastern Univ Bouvé Coll of Health Sciences, Boston, MA; Robert B. Wallace, Univ of Iowa Coll of Public Health, Iowa City, IA; Becky A. Briesacher, Northeastern Univ Bouvé Coll of Health Sciences, Boston, MA; Christopher F. Baum, Boston Coll, Boston, MA; Ichiro Kawachi, Harvard Sch of Public Health, Boston, MA; Daniel Kim, Northeastern Univ Bouvé Coll of Health Sciences, Boston, MA

3:00 PM

Board # 196

Trajectories of Oral Anticoagulation Adherence After First Atrial Fibrillation Diagnosis

**Inmaculada Hernandez** , Meiqi He, Nemin Chen, Univ Pittsburgh, Pittsburgh, PA; Samir Saba, Univ Pittsburgh Medical Ctr, Pittsburgh, PA; Walid Gellad, Univ Pittsburgh, Pittsburgh, PA

3:00 PM

Board # 197

Omega-3 Fatty Acid Biomarkers and Incident Type 2 Diabetes: An Individual Participant-level Pooling Project of 20 Prospective Cohort Studies

**Frank Qian** , Andres V Ardisson Korat, Dept of Nutrition, Harvard T.H. Chan Sch of Public Health, Boston, MA; Fumiaki Imamura, Medical Res Council Epidemiology Unit, Univ of Cambridge, Cambridge, United Kingdom; Matti Marklund, Dept of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala Univ, Uppsala, Sweden; Nathan Tintle, Dept of Mathematics and Statistics, Dordt Coll, Sioux Center, IA; Jyrki K Virtanen, Inst of Public Health and Clinical Nutrition, Univ of Eastern Finland, Kuopio, Finland; Xia Zhou, Div of Epidemiology and Community Health, Univ of Minnesota Sch of Public Health, Minneapolis, MN; Julie K Bassett, Cancer Epidemiology and Intelligence Div, Cancer Council Victoria, Melbourne, Australia; Heidi Lai, Friedman Sch of Nutrition Science and Policy, Tufts Univ, Boston, MA; Yoichiro Hirakawa, Dept of Epidemiology and Public Health, Graduate Sch of Medical Sciences, Kyushu Univ, Fukuoka, Japan; Kuo-Liong Chien, Inst of Epidemiology and Preventive Med, Coll of Public Health, Natl Taiwan Univ, Taipei, Taiwan; Alexis C Frazier-Wood, US Dept of Agriculture/Agricultural Res Service, Children's Nutrition Res Ctr, Houston, TX; Maria Lankinen, Inst of Public Health and Clinical Nutrition, Univ of Eastern Finland, Kuopio, Finland; Rachel A Murphy, Univ of British Columbia, Vancouver, BC, Canada; Cecilia Samieri, Univ of Bordeaux, INSERM, Bordeaux Population Health Res Ctr, UMR 1219, Bordeaux, France; Johanna M Geleijnse, Div of Human Nutrition, Wageningen Univ, Wageningen, Netherlands; Vanessa de Mello, Inst of Public Health and Clinical Nutrition, Univ of Eastern Finland, Kuopio, Finland; Nita G Forouhi, Medical Res Council Epidemiology Unit, Univ of Cambridge, Cambridge, United Kingdom; InterAct Consortium; Jason H Wu, The George Inst for Global Health, Faculty of Med, Univ of New South Wales, Sydney, Australia; Rozenn N Lemaitre, Cardiovascular Health Res Unit, Dept of Med, Univ of Washington, Seattle, WA; Renata Micha, Dariush Mozaffarian, Friedman Sch of Nutrition Science and Policy, Tufts Univ, Boston, MA; Qi Sun, Dept of Nutrition, Harvard T.H. Chan Sch of Public Health, Boston, MA

3:00 PM

Board # 198

Association of MIND Diet Adherence With Brain Volume, Silent Brain Infarcts and Brain Atrophy in the Framingham Heart Study

**Debora Melo van Lent** , Glenn Biggs Inst for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX; Adrienne O'Donnell, Dept of Biostatistics- Boston Univ Sch of Public Health, Boston, MA; Paul Jacques, Jean Mayer USDA Human Nutrition Res Ctr on Aging - Tufts Univ, Boston, MA; Charles DeCarli, Dept of Neurology - Univ of California-Davis, Sacramento, CA; Michael Wagner, German Ctr for Neurodegenerative Diseases (DZNE), Bonn, Germany; Alexa S. Beisler, Dept of Biostatistics- Boston Univ Sch of Public Health, Boston, MA; Vasan Ramachandran, Dept of Neurology- Boston Univ Sch of Med, Boston, MA; Sudha Seshadri, Glenn Biggs Inst for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX; Jayandra J. Himali, Dept of Biostatistics- Boston Univ Sch of Public Health, Boston, MA; Matthew Pase, Ctr for Human Psychopharmacology- Swinburne Univ of Technology, Hawthorn, Australia

3:00 PM

Board # 199

Directly Measured Triglyceride-Rich Lipoprotein Cholesterol and Small Dense LDL-Cholesterol Concentrations Associate With Incident Cardiovascular Disease: Prospective Data From the Women's Health Study

**Edward K Duran** , Brigham and Women's Hosp, Boston, MA; Aaron W Aday, Vanderbilt Univ Medical Ctr, Nashville, TN; Nancy Cook, Julie E Buring, Paul M Ridker, Aruna D Pradhan, Brigham and Women's Hosp, Boston, MA

3:00 PM

Board # 200

Proteomic Signatures of Cardiovascular Risk Factors: A Cross-sectional Analysis of the Plasma Proteome in the Framingham Heart Study

**Laura Corlin** , Tufts Univ Sch of Med, Boston, MA; Chunyu Liu, Martin G Larson, Boston Univ, Sch of Public Health, Boston, MA; Ramachandran S Vasan, Boston Univ, Dept of Med, Boston, MA

3:00 PM

Board # 201

County Poverty Disproportionately Effects Mortality in Heart Failure Compared to Coronary Heart Disease

**Khansa Ahmad** , Edward Chen, Umair Nazir, Amal Trivedi, Sebhat Erqou, Wen-chih Wu, Brown Univ, Providence, RI

3:00 PM

Board # 202

Metabolome-Wide Association Study With Habitual Physical Activity Among 4119 U.S. Participants

**Ming Ding** , Jessica Lasky-Su, Harvard Sch of Public Health, Boston, MA; Kathryn Rexrode, Harvard Medical Sch, Boston, MA; I-min Lee, Harvard Sch of Public Health, Boston, MA; Clary Clish, Broad Inst, Cambridge, MA; A Heather Eliassen, Walter Willett, Frank Hu, Peter Kraft, Harvard Sch of Public Health, Boston, MA

3:00 PM

Board # 203

Genetic Predisposition to Obesity and Healthful Plant-Based Diet in Risks of Hypertension and Cardiovascular Disease: Gene-Diet Interaction Analyses in the UK Biobank

**Yoriko Heianza** , Tao Zhou, Dianjianyi Sun, Tulane Univ, New Orleans, LA; Lu Qi, Harvard T.H. Chan Sch of Public Health; Tulane Univ, New Orleans, LA

3:00 PM

Board # 204

Dietary Inflammatory Potential is Associated with Cardiovascular Disease Risk in Two Large Prospective Cohort Studies of US Men and Women

**Jun Li** , Donghoon Lee, Yanping Li, Fred Tabung, Shilpa Bhupathiraju, Edward L. Giovannucci, Harvard T.H. Chan Sch of Public Health, Boston, MA; JoAnn E. Manson, Brigham and Women's Hosp, Boston, MA; Eric B. Rimm, Walter C. Willett, Harvard T.H. Chan Sch of Public Health, Boston, MA; Kathryn M. Rexrode, Brigham and Women's Hosp, Boston, MA; Frank Hu, Harvard T.H. Chan Sch of Public Health, Boston, MA

3:00 PM

Board # 205

Socioeconomic Status and Incident Heart Failure Among Individuals with Diabetes, Obesity and Metabolic Syndrome: The Atherosclerosis Risk in Communities (ARIC) Study

**Amira O Collison** , Lena M Mathews, Johns Hopkins Sch of Med, Baltimore, MD; Lucia Kwak, Johns Hopkins Sch of Public Health, Baltimore, MD; Priya Palta, Univ of North Carolina Gillings Sch of Global Public Health, Chapel Hill, NC; Kunihiro Matsushita, Johns Hopkins Sch of Med, Baltimore, MD; April P Carson, Univ of Alabama at Birmingham Sch of Public Health, Birmingham, AL; Deidra C Crews, Sherita H Golden, Johns Hopkins Sch of Med, Baltimore, MD; Priya Vart, Johns Hopkins Sch of Public Health, Baltimore, MD; Lisa A Cooper, Josef Coresh, Johns Hopkins Sch of Med, Baltimore, MD; Gerardo Heiss, Univ of North Carolina Gillings Sch of Global Public Health, Chapel Hill, NC; Chiadi E Ndumele, Johns Hopkins Sch of Med, Baltimore, MD

3:00 PM

Board # 206

Body Fat and Cardiovascular Disease Risk in Postmenopausal Women With Normal Body Mass Index: the Women's Health Initiative

**Guo-Chong Chen** , Rhonda Arthur, Albert Einstein Coll of Med, Bronx, NY; Neil M. Iyengar, Memorial Sloan Kettering Cancer Ctr, New York, NY; Victor Kamensky, Xiaonan Xue, Albert Einstein Coll of Med, Bronx, NY; Sylvia Wassertheil-Smoller, Weill Cornell Medical Coll,, New York, NY; Matthew A. Allison, Univ of California, San Diego, CA; Aladdin H. Shadyab, Univ of California San Diego Sch of Med, La Jolla, CA; Robert A. Wild, Oklahoma Univ Health Sciences Ctr, Oklahoma, OK; Yangbo Sun, Univ of Iowa, Iowa, IA; Hailey R. Banack, Jean Wactawski-Wende, State Univ of New York at Buffalo, Buffalo, NY; JoAnn E. Manson, Brigham and Women's Hosp, Harvard Medical Sch, Boston, NY; Marcia L. Stefanick, Stanford Univ Sch of Med, Stanford, CA; Andrew J. Dannenberg, Weill Cornell Medical Coll, New York, NY; Thomas E. Rohan, Qibin Qi, Albert Einstein Coll of Med, Bronx, NY

3:00 PM

Board # 207

Plasma Homocysteine is Causally Associated With Ischemic Stroke in a Han Chinese Population: A Mendelian Randomization Study

**Zhengbao Zhu** , Tanika N. Kelly, Tulane Univ, New Orleans, LA; Yonghong Zhang, Soocohw Univ, Suzhou, China; Changwei Li, Univ of Georgia, Athens, GA; Aili Wang, Tan Xu, Soocohw Univ, Suzhou, China; Xiao Sun, Mengyao Shi, Tulane Univ, New Orleans, LA; Xiaoqing Bu, Soocohw Univ, Suzhou, China; Jing Chen, Jiang He, Tulane Univ, New Orleans, LA

3:00 PM

Board # 208

Cardiovascular Health Behavior and Health Factor Trends (1999-2014) and Projections to 2050: Results From the National Health and Nutrition Examination Surveys

**Sadiya S Khan** , Nilay S. Shah, Hongyan Ning, Darwin R. Labarthe, Mark D. Huffman, Joshua D. Bundy, Northwestern Univ, Chicago, IL; Martin O'Flaherty, Simon Capewell, Univ of Liverpool, Liverpool, United Kingdom; Donald M. Lloyd-Jones, Northwestern Univ, Chicago, IL

3:00 PM

Board # 209

Hypocholesterolemic Effect of Dietary Stearic Acid May Be Partly Mediated via Alterations in Fecal Bile Acid Metabolism

**Nirupa R Matthan** , Jean Mayer USDA HNRCA at Tufts Univ, Boston, MA; Jose Rodríguez-Morató, Univ Pompeu Fabra, Barcelona, Spain; Huicui Meng, Sch of Public Health (Shenzhen), Sun Yat-sen Univ, Guangzhou, Guangdong Province, China; Rebecca Cohen, Jean Galluccio, Gregory Dolnikowski, Alice H Lichtenstein, Jean Mayer USDA HNRCA at Tufts Univ, Boston, MA

3:00 PM

Board # 210

Caregiving, Stress, and Depression Are Associated with Lower Achievement of Cardiovascular Health Metrics Among Women: The AHA's Life's Simple 7 and the Go Red for Women Strategically Focused Research Network

**Brooke Aggarwal** , Nour Makarem, Stephanie Byun, Zara Mayat, Ming Liao, Heidi Mochari Greenberger, Columbia Univ Medical Ctr, New York, NY

3:00 PM

Board # 211

Race and Sex-Based Disparities Associated With Carotid Endarterectomy in the Atherosclerosis Risk in Communities (ARIC) Study

**Caitlin W. Hicks** , Johns Hopkins Univ Sch of Med, Baltimore, MD; Natalie Daya, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; James H. Black III, Johns Hopkins Univ Sch of Med, Baltimore, MD; Kunihiro Matsushita, Elizabeth Selvin, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD

3:00 PM

Board # 212

Better Neighborhood Characteristics Are Associated with Ideal Cardiovascular Health Among Blacks: Results From the Morehouse-Emory Cardiovascular (MECA) Center for Health Equity

**Jeong Hwan Kim** , Emory Univ, Atlanta, GA; Peter Baltrus, Morehouse Sch of Med, Atlanta, GA; Matthew L Topel, Chang Liu, Yi-An Ko, Emory Univ, Atlanta, GA; Mahasin Mujahid, Univ of California Berkeley, Berkeley, CA; Viola Vaccarino, Emory Univ, Atlanta, GA; Mario Sims, Univ of Mississippi, Jackson, MS; Mohamed Mubasher, Morehouse Sch of Med, Atlanta, GA; Ahsan Khan, Kiran Ejaz, Charles Searles, Emory Univ, Atlanta, GA; Sandra B Dunbar, Emory Univ Sch of Nursing, Atlanta, GA; Priscilla Pemu, Herman Taylor, Morehouse Sch of Med, Atlanta, GA; Arshed A Quyyumi, Tené T Lewis, Emory Univ, Atlanta, GA

3:00 PM

Board # 213

The Natural History of Cigarette Smoking From Childhood to Middle-Age: The International Childhood Cardiovascular Cohort (i3C) Consortium

**Tian Hu** , Sch of Public Health, Univ of Minnesota, Minneapolis, MN; Seana L Gall, Menzies Inst for Medical Res, Univ of Tasmania, Hobart, Australia; Rachel Widome, Sch of Public Health, Univ of Minnesota, Minneapolis, MN; Lydia A Bazzano, Tulane Univ Sch of Public Health and Tropical Med, New Orleans, LA; Trudy L Burns, Coll of Public Health, Univ of Iowa, Iowa City, IA; Stephen R Daniels, Univ of Colorado Sch of Med, Aurora, CO; Terence Dwyer, Oxford Martin Sch, Oxford Univ, Oxford, United Kingdom; Johanna Ikonen, Markus Juonala, Mika Kahonen, Univ of Turku, Turku, Finland; Ronald J Prineas, Wake Forest Univ, Winston-Salem, NC; Olli T Raitakari, Univ of Turku, Turku, Finland; Alan R Sinaiko, Julia Steinberger, Sch of Med, Univ of Minnesota, Minneapolis, MN; Elaine M URBINA, Univ of Cincinnati Coll of Med, Cincinnati, OH; Alison Venn, Menzies Inst for Medical Res, Univ of Tasmania, Hobart, Australia; Jorma Viikari, Univ of Turku, Turku, Finland; Jessica G Woo, Univ of Cincinnati Coll of Med, Cincinnati, OH; David R Jacobs Jr, Sch of Public Health, Univ of Minnesota, Minneapolis, MN

3:00 PM

Board # 214

Association Between Neighborhood Characteristics, Personal Resilience, and Arterial Stiffness Among Blacks: Results From the Morehouse-Emory Cardiovascular (MECA) Center for Health Equity

**Jeong Hwan Kim** , Matthew L Topel, Tené T Lewis, Emory Univ, Atlanta, GA; Peter Baltrus, Morehouse Sch of Med, Atlanta, GA; Chang Liu, Yi-An Ko, Emory Univ, Atlanta, GA; Mahasin Mujahid, Univ of California Berkeley, Berkeley, CA; Viola Vaccarino, Emory Univ, Atlanta, GA; Mario Sims, Univ of Mississippi, Jackson, MS; Mohamed Mubasher, Morehouse Sch of Med, Atlanta, GA; Ahsan Khan, Kiran Ejaz, Charles Searles, Emory Univ, Atlanta, GA; Sandra B Dunbar, Emory Univ Sch of Nursing, Atlanta, GA; Priscilla Pemu, Herman Taylor, Morehouse Sch of Med, Atlanta, GA; Arshed A Quyyumi, Emory Univ, Atlanta, GA

3:00 PM

Board # 215

Poor Lower Extremity Physical Function Increases Risk for Cardiovascular Disease Events in Older Women: The OPACH Study

**John Bellettiere** , UC San Diego, La Jolla, CA; Michael J. LaMonte, SUNI Buffalo, Buffalo, NY; Jonathan Unkart, UC San Diego, La Jolla, CA; Charles Kooperberg, Fred Hutchinson Cancer Res Ctr, Seattle, WA; Marcia L. Stefanick, Stanford Univ, Stanford, CA; Chongzhi Di, Fred Hutchinson Cancer Res Ctr, Seattle, WA; Andrea Z. LaCroix, UC San Diego, La Jolla, CA

3:00 PM

Board # 216

Association of Dietary Patterns and Lifetime Risk of Heart Failure: The Cardiovascular Disease Lifetime Risk Pooling Project

**Sadiya S Khan** , Wenze Zhong, Hongyan Ning, Amanda Paluch, Norrina B. ALLEN, Clyde W. Yancy, John T. Wilkins, Donald M. Lloyd-Jones, Northwestern Univ Feinberg Sch of Med, Chicago, IL

3:00 PM

Board # 217

Novel Serum Metabolites Associate With Diastolic Function: Evidence From the Bogalusa Heart Study

**Alexander C Razavi** , Camilo Fernandez, Tulane Universty Sch of Med, New Orleans, LA; Xuenan Mi, Jiang He, Lydia Bazzano, Jovia Nierenberg, Shengxu Li, Tanika N Kelly, Tulane Universty Sch of Public Health and Tropical Med, New Orleans, LA

3:00 PM

Board # 218

Self-Identified Hispanic/Latino Dietary Identity is Differentially Associated With Diet Quality and Food Intake Across Ethnic Heritages in the Hispanic Community Health Study/Study on Latinos

**Josiemer Mattei** , Martha Tamez, Harvard Chan Sch Public Health, Boston, MA; Daniela Sotres-Alvarez, Univ of North Carolina, Chapel Hill, NC; Anna Maria Siega-Riz, Univ of Virginia, Charlottesville, VA; Linda C Gallo, San Diego State Univ, San Diego, CA; Linda Van Horn, Northwestern Univ Feinberg Sch of Med, Chicago, IL; Martha Daviglus, Univ of Illinois, Chicago, IL; Denise C Vidot, Tali Elfassy, Univ of Miami, Miami, FL; Robert C Kaplan, Albert Einstein Coll of Med, Bronx, NY

3:00 PM

Board # 219

Racial Disparity in Habitual Sleep Pattern Among Adolescents is Modified by Caloric Intake

**Fan He** , Huamei Dong, Julio Fernandez-Mendoza, Edward O. Bixler, Jiangang Liao, Alexandros N. Vgontzas, Duanping Liao, Penn State Coll of Med, Hershey, PA

3:00 PM

Board # 220

Sleep Characteristics and Adverse Social Exposures Elevate Blood Pressure in Young Black Females

**Jewel Scott** , Susan Silva, Leigh Ann Simmons, Duke Univ Sch of Nursing, Durham, NC

# Best of AHA Specialty Conferences

## BASC.06 - Best of AHA Specialty Conferences: QCOR 2019

#### Best of Specialty Conferences, Science and Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:30 PM

3:00 PM

Board # 258

Worse Patency in Women After Endovascular Peripheral Vascular Intervention

**Niveditta Ramkumar** , The Dartmouth Inst, Lebanon, NH; Bjoern D Suckow, Dartmouth-Hitchcock Medical Ctr, Lebanon, NH; Todd A Mackenzie, The Dartmouth Inst, Lebanon, NH; Art Sedrakyan, Weil Cornell Medical Coll, New York, NY; Jeremiah R Brown, The Dartmouth Inst, Lebanon, NH; Philip P Goodney, Dartmouth-Hitchcock Medical Ctr, Lebanon, NH

3:00 PM

Board # 259

Social Determinants of Health and 90 Day Mortality after Hospitalization for Heart Failure in the REasons for Geographic and Racial differences in Stroke (REGARDS) Study

**Madeline R. Sterling** , Joanna Bryan Ringel, Laura C. Pinheiro, Monika M. Safford, Weill Cornell Medical Coll, New York, NY; Emily B. Levitan, Univ of Alabama, Birmingham, AL; Erica Phillips, Parag Goyal, Weill Cornell Medical Coll, New York, NY

3:00 PM

Board # 260

Transcatheter Aortic Valve Replacement is Associated with a Reduction in Hospitalization Rates: Insights from Nationwide Readmission Database

**Ahmed Elkaryoni** , Saint Luke's Mid America Heart Inst, Univ Of Missouri Kansas-City., kansas city, MO; Mohammed Qintar, David J Cohen, Adnan K Chhatriwalla, Suzanne V Arnold, Saint Luke's Mid America Heart Inst, Univ Of Missouri Kansas-City., Kansas City, MO

3:00 PM

Board # 261

Association of Medicaid Expansion with Cardiovascular Mortality - A Quasi-experimental Analysis

**Sameed Ahmed M Khatana** , Anjali Bhatla, Ashwin S Nathan, Jay Giri, Univ of Pennsylvania, Philadelphia, PA; Changyu Shen, Dhruv S Kazi, Robert W Yeh, Beth Israel Deaconess Medical Ctr, Boston, MA; Peter W Groeneveld, Univ of Pennsylvania, Philadelphia, PA

3:00 PM

Board # 262

Effect of Cardiovascular Health and Text Messaging (CHAT) on Risk Factor Management in Patients with Coronary Heart Disease: A Randomized Clinical Trial

Xin Zheng, Natl Clinical Res Ctr of Cardiovascular Diseases, State Key Lab of Cardiovascular Disease, Fuwai Hosp, Natl Ctr for Cardiovascular Diseases, Chinese Acad of Medical Sciences and Peking Union Medical Coll, beijing, China; **Erica S Spatz** , Ctr for Outcomes Res and Evaluation, Yale Univ/Yale-New Haven Hosp, New Haven, CT; Xueke Bai, Xiqian Huo, Natl Clinical Res Ctr of Cardiovascular Diseases, State Key Lab of Cardiovascular Disease, Fuwai Hosp, Natl Ctr for Cardiovascular Diseases, Chinese Acad of Medical Sciences and Peking Union Medical Coll, beijing, China; Qinglan Ding, Ctr for Outcomes Res and Evaluation, Yale Univ/Yale-New Haven Hosp, New Haven, CT; Paul Horak, Stanford Univ Sch of Med, Stanford, CA; Xuekun Wu, Wenchi Guan, Natl Clinical Res Ctr of Cardiovascular Diseases, State Key Lab of Cardiovascular Disease, Fuwai Hosp, Natl Ctr for Cardiovascular Diseases, Chinese Acad of Medical Sciences and Peking Union Medical Coll, beijing, China; Clara K Chow, Westmead Applied Res Ctr, Faculty of Med and Health, Univ of Sydney and The George Inst for Global Health, Sydney, Australia; Xiaofang Yan, Ying Sun, Xiuling Wang, Haibo Zhang, Jiamin Liu, Jing Li, Xi Li, Natl Clinical Res Ctr of Cardiovascular Diseases, State Key Lab of Cardiovascular Disease, Fuwai Hosp, Natl Ctr for Cardiovascular Diseases, Chinese Acad of Medical Sciences and Peking Union Medical Coll, beijing, China; John A Spertus, Health Outcomes Res, Saint Luke's Mid America Heart Inst/Univ of Missouri-Kansas City, Kansas city, MO; Frederick A Masoudi, Div of Cardiology, Univ of Colorado Anschutz Medical Campus, Aurora, CO; Harlan M Krumholz, Ctr for Outcomes Res and Evaluation, Yale Univ/Yale-New Haven Hosp, Section of Cardiovascular Med, Yale Univ Sch of Med, Dept of Health Policy and Management, Yale Univ Sch of Public Health, New Haven, CT

3:00 PM

Board # 263

The Corrie Myocardial infarction, COmbined-device, Recovery Enhancement (MiCORE) Study: 30-Day Readmission Rates and Cost-Effectiveness of a Novel Digital Health Intervention for Acute Myocardial Infarction Patients

**Francoise A. Marvel** , Johns Hopkins Univ Sch of Med, Baltimore, MD; Erin M. Spaulding, Johns Hopkins Sch of Nursing, Baltimore, MD; Matthias Lee, Ciccarone Preventive Cardiology Ctr, Baltimore, MD; William Yang, Seth S. Martin, Johns Hopkins Univ Sch of Med, Baltimore, MD

3:00 PM

Board # 264

Comparative Effectiveness and Safety of Oral Anticoagulants across Baseline Kidney Function

**Xiaoxi Yao** , Mayo Clinic, ROCHESTER, MN; Jonathan W. Inselman, Nilay D. Shah, Mayo Clinic, Rochester, MN; Joseph S. Ross, Yale Sch of Med, New Haven, CT; Rima Izem, Children's Natl Hosp, Washington DC, DC; David Graham, David Martin, US Food and Drug Admin, White Oak, MD; Aliza Thompson, Mary R Southworth, U.S. Food and Drug Admin, White Oak, MD; Konstantinos C. Siontis, Che G. Ngufor, Karl Nath, Mayo Clinic, Rochester, MN; Nihar R. Desai, Yale-New Haven Hosp, New Haven, CT; Brahmajee Nallamothu, Rajiv Saran, Univ of Michigan, Ann Arbor, MI; Peter A. Noseworthy, Mayo Clinic, Rochester, MN

3:00 PM

Board # 265

Reduction in Laboratory Associated Cost Through Education Based Gatekeeping

**Abdul Basit** , Hyma Polimera, Simranjit Bedi, Britt Marshall, Brian McGillen, Ron Domen, David Towery, Tariq Ahmad, Penn State Milton S. Hershey Medical Ctr, Hershey, PA

3:00 PM

Board # 266

Effect of Oral Anticoagulation Use on Thromboembolic Risk and Bleeding in Women Compared with Men with Atrial Fibrillation: Findings from the PINNACLE Data Registry

**Kamal Henderson** , Denver Veteran's Affairs Medical Ctr, Aurora, CO; Phillip Jones, Saint Lukes Health System, Kansas City, MO; Pamela Peterson, Frederick Masoudi, Stacie Daugherty, Univ of Colorado Sch of Med, Aurora, CO

3:00 PM

Board # 267

BRAVE: Blood Pressure and Vascular Health Around Menopause

**Muhammad Ahmer Wali** , RI -McGill Univ Health Ctr, Montreal, QC, Canada; Valeria Raparelli, Sapienza - Univ of Rome, Experimental Med Dept, Rome, Italy; Stella S Daskalopoulou, McGill Univ Health Ctr, Montreal, QC, Canada; Louise Pilote, RI -McGill Univ Health Ctr, Montreal, QC, Canada

3:00 PM

Board # 268

**Association of Ambient Air PM** 2.5 **Concentration with Health Status in Patients Following Myocardial Infarction**

**Ali O Malik** , Poghni Peri-Okonny, Vittal Hejjaji, Philip G Jones, Paul Chan, John Spertus, Saint Luke's Mid America Heart Inst, Kansas City, MO

3:00 PM

Board # 269

Disparities and Impact of Medicaid Expansion on Left Ventricular Assist Device Implantation and Outcomes

**Xiaowen Wang** , Brigham and Women's Hosp, Boston, MA; Alina A. Luke, Justin M. Vader, Thomas M. Maddox, Karen E. Joynt Maddox, Washington Univ, Saint Louis, MO

3:00 PM

Board # 270

Patterns of Addiction Treatment for Patients Undergoing Cardiac Surgery for Infective Endocarditis Associated with Intravenous Drug Use

**Max Jordan Nguemeni Tiako** , Seong Hong, Syed Usman Bin Mahmood, Umer Darr, Abeel Mangi, Manisha Jutthani-Mehta, Arnar Geirsson, Yale Sch of Med, New Haven, CT

3:00 PM

Board # 271

PredischaRge Initiation of Ivabradine in the ManagEment of Heart Failure: Results of the PRIME-HF Trial

**Robert John Mentz** , Adam DeVore, Gudaye Tasissa, Duke Clinical Res Inst, Durham, NC; John Heitner, New York Methodist Hosp, Brooklyn, NY; Ileana Pina, Montefiore, Bronx, NY; Anuradha Lala, Mount Sinai, New York, NY; Robert Cole, Inova, Arlington, VA; David Lanfear, Henry Ford, Detroit, MI; Chetan Patel, Duke Univ Medical Ctr, Durham, NC; Mahazarin Ginwalla, Univ Hosp Cleveland Medical Ctr, Cleveland, OH; Wayne Old, Sentara Cardiovascular Res Inst, Norfolk, VA; Abraham Salacata, Great Lakes Heart Ctr of Alpena, Alpena, MI; Tim Peterson, Robert Bigelow, Duke Clinical Res Inst, Durham, NC; Gregg Fonarow, Ahmanson-UCLA Cardiomyopathy Ctr, Univ of California, Los Angeles, Los Angeles, CA; Adrian Hernandez, Duke Univ Medical Ctr, Durham, NC

3:00 PM

Board # 272

Using the VA National Cardiac Device Surveillance Program to Monitor the Safety of Cardiovascular Implantable Electronic Devices

**Sanket S. Dhruva** , San Francisco VA Medical Ctr/UCSF, San Francisco, CA; Mary A. Whooley, UCSF Sch of Med, San Francisco, CA; Minang P Turakhia, Stanford Univ Sch of Med, Stanford, CA; Merritt H Raitt, Portland Veterans Affairs Health Care System, Portland, OR; Gary Tarasovsky, San Francisco Veterans Affairs Health Care System, San Francisco, CA; Lindsey Rosman, Yale Univ Sch of Med, New Haven, CT; Michael E Matheny, Vanderbilt Univ Sch of Med, Nashville, TN

3:00 PM

Board # 273

Cost-Effectiveness Analysis of the Sentinel Cerebral Embolic Protection Device During Transcatheter Aortic Valve Replacement

Bart S Ferket, Icahn Sch of Med Mt Sinai, New York, NY; **Jacob R. Morey** , Icahn Sch of Med at Mount Sinai, New York, NY; Annetine C. Gelijns, Alan J. Moskowitz, Gennaro Giustino, Icahn Sch of Med Mt Sinai, New York, NY

3:00 PM

Board # 274

Healthcare Resource Use and Expenditures in Younger Women and Men Newly Diagnosed with Paroxysmal Supraventricular Tachycardia (PSVT)

**Naomi C Sacks** , Precision Xtract, Boston, MA; Katie Everson, Precision Health Economics, Austin, TX; Philip L Cyr, Precision Xtract, Boston, MA; David R Wood, Milestone Pharmaceuticals, Montreal, QC, Canada; Sean D Pokorney, Duke Univ Medical Ctr, Durham, NC

3:00 PM

Board # 275

PCSK9 Inhibitor Use and Health Characteristics Among High-Risk Patients with Atherosclerotic Cardiovascular Disease

**Elias J Dayoub** , Ashwin S Nathan, Srinath Adusumalli, Peter W Groeneveld, Perelman Sch of Med, Univ of Pennsylvania, Philadelphia, PA

3:00 PM

Board # 276

Real World Outpatient Treatment Patterns of Patients with Cancer-Associated Venous Thromboembolism in the US

Jennifer D Guo, Bristol-Myers Squibb, Lawrenceville, NJ; Patrick Hlavacek, Pfizer Inc., New York, NY; **Tayla Poretta** , Gail Wygant, Daniel C Lane, Bristol-Myers Squibb, Lawrenceville, NJ; Magdaliz Gorritz, Xin Wang, Chi-Chang Chen, IQVIA, Plymouth Meeting, PA; Xianying Pan, Jigar Rajpura, Brian Stwalley, Lisa Rosenblatt, Bristol-Myers Squibb, Lawrenceville, NJ

3:00 PM

Board # 277

Adding Social and Functional Determinants of Health Improves Readmission Risk Prediction in Urban Underserved Adults Hospitalized for Acute Myocardial Infarction

**Oanh Nguyen** , Anil N. Makam, Univ of California, San Francisco, San Francisco, CA; Christopher R. Clark, Parkland Health & Hosp System, Dallas, TX; Sandeep R. Das, Ethan A. Halm, UT Southwestern Medical Ctr, Dallas, TX

# Expert Theater

## ET.20 - AHA - Rise Above Heart Failure

#### Learning Studio 2, Booth # 7

### Sunday, November 17, 2019, 3:00 PM - 4:30 PM

This is not a CME/CE certified session

# FIT Event

## FIT.09 - What You Need to Know for a Career in Interventional Cardiology

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:45 PM

This is not a CME/CE certified session

# FIT Event

## FIT.08 - What You Need to Know for a Career in Multimodality Cardiac Imaging

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Sunday, November 17, 2019, 3:00 PM - 3:45 PM

This is not a CME/CE certified session

# Hall

## HT.08 - Afib Detection on Smart Watches One Year Later: What Have We Learned?

#### Health Innovation Pavilion, Heart Hub, Science and Technology Hall, Level 2

### Sunday, November 17, 2019, 3:00 PM - 3:50 PM

3:00 PM

Moderator

Mintu Turakhia, Palo Alto, CA

3:00 PM

Invited Presenter

Mellanie True Hills, Dallas, TX

3:00 PM

Invited Presenter

Kenneth Mahaffey, Stanford, CA

3:00 PM

Invited Presenter

Khaldoun Tarakji, Cleveland, OH

3:00 PM

Invited Presenter

Judith C Lenane, Lincolnshire, IL

# Hall

## EA.HT.593 - You and Your EP Connections: Social Media, Apps and Tools for the Busy Clinician

#### EP Central

### Sunday, November 17, 2019, 3:00 PM - 4:00 PM

3:00 PM

Moderator

Rakesh Gopinathannair, Louisville, KY

3:00 PM

Moderator

Mina K CHUNG, Cleveland, OH

3:00 PM

Apps and Tools for Your Patient: What to Advise and How to Handle the Information

Khaldoun Tarakji, Cleveland, OH

3:15 PM

Insights into EP Blogging

John Mandrola, Louisville, KY

3:45 PM

Social Media - Twitter, Facebook, Doximity - How to Get Involved and How to Connect

JANET HAN, Los Angeles, CA

3:30 PM

Apps and Tools for the Busy EP

Arun Raghav Mahankali Sridhar, Silver Spring, MD

# Simulation

## SIM.12 - Interactive Digital iWall Experiential Learning

#### Simulation Zone - Heart Hub, Hall C

### Sunday, November 17, 2019, 3:00 PM - 4:00 PM

3:00 PM

Invited Presenter

Tina Baykaner, Palo Alto, CA

# Expert Theater

## ET.21 - Portola

#### Learning Studio 1, Booth # 5

### Sunday, November 17, 2019, 3:15 PM - 4:00 PM

This is not a CME/CE certified session

# Abstract Rapid Fire Oral

## HF.RFO22 - Clinical Practice and Outcomes in Heart Failure

#### Zone 2, Science and Technology Hall

### Sunday, November 17, 2019, 3:40 PM - 4:30 PM

3:40 PM

Moderator

Justin L Grodin, Dallas, TX

3:40 PM

Contemporary Survival Trends in Dilated Cardiomyopathy

Antonio Cannatà, Marco Merlo, Carola Pio Loco, Federica Ramani, Giulia Barbati, **Thomas Caiffa** , Bruno Pinamonti, Renata Korcova, Massimo Zecchin, Davide Stolfo, Gianfranco Sinagra, ASUITs, Trieste, Italy

3:45 PM

Q & A

3:50 PM

Prognosis in Patients With Cardiac Sarcoidosis Detected by PET or CMR

Mark Doyle, Indu G Poornima, Kinan Kassar, Michael Popeck, Allegheny General Hosp, Pittsburgh, PA; Nael Aldweib, Brigham and Women's Hosp, Boston, MA; Geetha Rayarao, Amresh Raina, Amit Thosani, **Robert W Biederman** , Allegheny General Hosp, Pittsburgh, PA

3:55 PM

Q & A

4:00 PM

Prognostic Significance of Serum Cholinesterase Level in Patients With Acute Decompensated Heart Failure: A Prospective Comparative Study With ALBI Score in Osaka Prefectural Acute Heart Failure Registry (OPAR)

**Masahiro Seo** , Osaka General Medical Ctr, Osaka city, Japan; Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Jun Nakamura, Kiyomi Kayama, Osaka General Medical Ctr, Osaka, Japan; Masatsugu Kawahira, Osaka General Medical Ctr, Oosaka, Japan; Kazuya Tanabe, Osaka General Medical Ctr, Osaka, Japan; Masatake Fukunami, Osaka General Medical Ctr, Osaka city, Japan

4:05 PM

Q & A

4:10 PM

Long-Term Cardiopoietic Cell Therapy in Ischemic Heart Failure: Improved Clinical Outcomes in Advanced Left Ventricular Enlargement Titrated by Treatment Intensity

**Jozef Bartunek** , OLV Hosp, Aalst, Belgium; Andre Terzic, Mayo Clinic, Rochester, MN; CHART-1 Investigators

4:15 PM

Q & A

4:20 PM

Clinical Practice Patterns in Percutaneous Mechanical Circulatory Support (MCS) for Shock in the Critical Care Cardiology Trials Network (CCCTN) Registry

**David D Berg** , Erin A Bohula, Brigham and Women's Hosp, Boston, MA; Christopher F Barnett, Benjamin B Kenigsberg, MedStar Washington Hosp Ctr, Washington, DC; Jeong-Gun Park, Brigham and Women's Hosp, Boston, MA; Sean Van Diepen, Univ of Alberta, Edmonton, AB, Canada; Jason N Katz, Univ of North Carolina, Chapel Hill, NC; David A Morrow, Brigham and Women's Hosp, Boston, MA; on behalf of the CCCTN Investigators

4:25 PM

Q & A

# Abstract Rapid Fire Oral

## LF.RFO28 - Immunity, Inflammation and CVD

#### Science and Technology Hall A, Booth 605, Level 2

### Sunday, November 17, 2019, 3:40 PM - 4:30 PM

3:40 PM

Moderator

Pradeep Natarajan, Boston, MA

3:40 PM

Cardiovascular Effects of Chimeric Antigen Receptor T-Cell (CART Cell) Therapy in Adults

**Benedicte Lefebvre** , Univ of Pennsylvania, Philadelphia, PA; Yu Kang, Philadelphia, PA; Noelle Frey, UPENN, Philadelphia, PA; Joseph R Carver, Penn Med, Philadelphia, PA; Marielle Scherrer-Crosbie, Univ of Pennsylvania, Philadelphia, PA

3:50 PM

Is Cardiovascular Risk and Mortality in Rheumatoid Arthritis Compared to Diabetes Mellitus and the General Population Overestimated?

**Brian B Logstrup** , Aarhus Univ Hosp, Aarhus N, Denmark; Torkell Ellingsen, Odense Univ Hosp, Odense, Denmark; Alma B Pedersen, Bianka B Darvalics, Kevin KW Olesen, Hans Erik Bøtker, Michael Mæng, Aarhus Univ Hosp, Aarhus, Denmark

4:00 PM

Novel Dual MTOR Inhibitors/AMPK Activators Attenuate Doxorubicin-Induced Cardiotoxicity

**Anindita Das** , Arun Samidurai, Virginia Commonwealth Univ, Richmond, VA; Laura G Corral, Leah Fung, Robert W Sullivan, Novomedix, Inc., San Diego, CA; Kyle W H Chan, Cathy A Swindlehurst, NovoMedix, San Diego, CA; Fadi N Salloum, Virginia Commonwealth Univ, Richmond, VA

4:10 PM

HIV Infection is Associated With Higher Repolarization Lability in the Multicenter AIDS Cohort Study (MACS)

**Amir S Heravi** , Johns Hopkins Sch of Med, Baltimore, MD; Lacey Etzkorn, Jacek Urbanek, Ciprian Crainiceanu, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Naresh M Punjabi, Hiroshi Ashikaga, Todd T Brown, Johns Hopkins Sch of Med, Baltimore, MD; Matthew J Budoff, Los Angeles Biomedical Res Inst, Torrance, CA; Amber D'Souza, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Jared W Magnani, Univ of Pittsburg, Pittsburgh, PA; Frank J Palella Jr., Northwestern Univ, Chicago, IL; Sean Altekruse, Natl Insts of Health, Bethesda, MD; Ronald D Berger, Katherine C Wu, Wendy S Post, Johns Hopkins Sch of Med, Baltimore, MD

4:20 PM

A Phewas Comparing the Pleiotropic Effects of Atorvastatin and Simvastatin Reveals Significantly Different Associations With Altered Mental Status

**Philip O Adejumo** , Vanderbilt Univ Medical Ctr, Nashville, TN; Qiping Feng, Vanderbilt Univ Medical, Nashville, TN; James G Linneman, Emili Leary, Peggy L Peissig, Marshfield Clinic Res Inst, Marshfield, WI; Jonathan D Mosley, C Michael M Stein, Dan M Roden, Joshua C Denny, Wei-qi Wei, Vanderbilt Univ Medical Ctr, Nashville, TN

# Abstract Rapid Fire Oral

## AT.RFO19 - Latest Advances in Vascular Remodeling and Regeneration

#### Zone 1, Science and Technology Hall

### Sunday, November 17, 2019, 3:40 PM - 4:30 PM

3:40 PM

PDGFRalpha Drives Pulmonary Vascular Progenitor Cells Recruitment, Vascular Remodeling and Pulmonary Hypertension Development

Julien Solinc, Jessica Raimbault-Machado, France Dierick, Lamiaa El Bernoussi, Bénédicte Hoareau-Coudert, Virginie Monceau, Fabrice Atassi, Giovanna Marazzi, David A Sassoon, INSERM, Paris, France; Richard Harvey, Victor Chang Cardiac Res Inst, Darlinghurst, Australia; Daniel Christ, Peter Schofield, Garvan Inst of Medical Res, Darlinghurst, Australia; Catherine Pavoine, Florent Soubrier, **Sophie Nadaud** , INSERM, Paris, France

3:45 PM

Q & A

3:50 PM

Activation of the Scaffolding Protein Merlin Causes Endothelial Dysfunction in Obesity

**Sarah Costantino** , Shafeeq A Mohammed, Univ of Zurich, Schlieren, Switzerland; Alexander Akhmedov, Zurich Univ, Schlieren, Switzerland; Stefano Masi, Agostino A Virdis, Univ of Pisa, Pisa, Italy; Thomas F Luescher, Francesco Paneni, Univ of Zurich, Schlieren, Switzerland

3:55 PM

Q & A

4:00 PM

Human Telomerase M-RNA Rescues Cellular Functions, Gene Regulation, and Chromatin Structure in Progeria Ipsc- Derived Endothelial Cells

**Anahita Mojiri** , Houston Methodist Res Inst, Houston, TX; Gianfranco Matrone, Univ of Edinburgh, Edinburgh; Brandon K Walther, Houston Methodist Res Inst, Houston, TX; Crystina Kriss, Houston Methoudist research Inst, Houston, TX; John P Cooke, Houston Methodist Res Ins, Houston, TX

4:05 PM

Q & A

4:10 PM

Light-sheet Imaging of Intact Ocular System and Quantitative Analysis of Retinal Vasculature

**Chih-Chiang Chang** , Parinaz Abiri, Michel Sun, Kyung In Baek, UCLA, Los Angeles, CA; Alison Chu, David Geffen Sch of Med UCLA, Los Angeles, CA; Jie Zheng, Kristina I Bostrom, UCLA, Los Angeles, CA; Lynn Gordon, David Geffen Sch of Med at UCLA, Los Angeles, CA; Yichen Ding, 430 S Fuller Ave, Los Angeles, CA; Tzung K Hsiai, UCLA Sch of Med Cardiology Div, Los Angeles, CA

4:15 PM

Q & A

4:20 PM

Endothelial Cell Specific Hspa12b Promotes Macrophage Polarization Toward to a Regenerative Phenotype Following Myocardial Infarction

Yana Wang 37601, **Kun Yang 37601** , Spencer Gill 37601, Min Fan, East Tennessee State Univ, Johnson City, TN; Fei Tu, East Tennessee State Univ, Johnson city, TN; Tuanzhu Ha, East Tennessee State Univ, Johnson City, TN; Li Liu, Nanjing Medical Univ, Nanjing; John Kalbfleisch, David L Williams, Chuanfu Li, East Tennessee State Univ, Johnson City, TN

4:25 PM

Q & A

# Abstract Rapid Fire Oral

## ST.RFO25 - Stroke Rapid Fire

#### Zone 4, Science and Technology Hall

### Sunday, November 17, 2019, 3:40 PM - 4:30 PM

3:40 PM

Moderator

Rebecca F Gottesman, Bethesda, MD

3:40 PM

Meta-Analysis of Secondary Prevention of Cryptogenic Stroke

**Babikir Kheiri** , Oregon Health & Science Univ, Portland, OR; Harsh Golwala, Oregon Health & Science Univ, Portland, MI; Mohammed Osman, Univ of West Virgina, Morgantow, WV; Khidir Dalouk, Oregon Health & Science Univ, Portland, OR; Eric Stecker, Knight Cardiovascular Inst, Portland, OR; Firas Zahr, Oregon Health & Science Univ, Portland, OR; Babak Nazer, Oregon Health & Sciences Univ, Portland, OR; Hind Wahiba Rahmouni, Oregon Health & Science Univ, Portland, OR

3:50 PM

Patient Foramen Ovale Closure versus Anti-Thrombotic Therapy for Patients With Cryptogenic Stroke: An Updated Meta-Analysis of Randomized Clinical Trials

**Harsh Agrawal** , Vaikom Mahadevan, UCSF, San Francisco, CA; Horst Sievert, CardioVascular Ctr, Frankfurt, Germany; Kendrick Shunk, UCSF, San Francisco, CA; Alok Dwivedi, Indika Mallawaarachchi, Texas Tech Univ Health Sciences Ctr, El Paso, TX; Tariq Siddiqui, Texas Tech Univ Health Sciences Ctr, El Paso , TX; Debabrata Mukherjee, Texas Tech Univ Health Sciences Ctr El Paso , El Paso, TX

4:00 PM

Embolic Stroke of Unknown Source is Associated With Atrial Fibrosis Similar to Atrial Fibrillation

**Anne Kroman** , Univ of Washington, Seatte, WA; Christian Mahnkopf, Klinikum Coburg, Coburg; Peter Kühnlein, Marcel Mitlacher, Klinikum Coburg, Coburg, Germany; Suresh Kumar Kulandhaisamy, Nazem W Akoum, Univ of Washington, Seattle, WA

4:10 PM

Efficacy of Sovateltide (PMZ-1620), a First-in-Class Neuronal Progenitor Cell Therapeutics, in Patients With Cerebral Ischemic Stroke

**Anil Gulati** , Pharmazz, Inc. and Midwestern Univ, Downers Grove, IL; Nilesh Radheshyam Agrawal, New Era Hosp, Nagpur, India; Deepti Vibha, All India Inst of Medical Sciences, New Delhi, India; U.K. Misra, Sanjay Gandhi Postgraduate Inst of Medical Sciences, Lucknow, India; Birinder Singh Paul, Dayanand Medical Coll, Ludhiana, India; Rajnish Kumar, Paras Hosp, Gurgaon, India; Jeyaraj D Pandian, Christian Medical Coll, Ludhiana, India; Manish S Lavhale, Pharmazz, Inc., Willowbrook, IL

4:20 PM

Peripheral Microvascular Endothelial Dysfunction Predicts Future Risk Of Ischemic Stroke: A Cohort Study

Takumi Toya, Jaskanwal Sara, Lilach O Lerman, **Amir LERMAN** , MAYO CLINIC, Rochester, MN

# Abstract Oral Session

## LF.AOS.564 - Exercise Training - Mechanistic Insights and Cardiovascular Adaptation

#### 201AB

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Exercise Training Ameliorates Vasodilator Capacity of Coronary Microvessels in Patients With Vasospastic Angina -A New Therapeutic Approach for the Coronary Functional Disorder-

**Jun Sugisawa** , Yasuharu Matsumoto, Akira Suda, Satoshi Tsuchiya, Kazuma Ohyama, Masashi Takeuchi, Tohoku Univ Graduate Sch of Med, Sendai, Japan; Kensuke Nishimiya, Tohoku Univ Grauate Sch of Med, Sendai, Japan; Mina Akizuki, Koichi Sato, Shoko Kajitani, Hideki Ota, Shohei Ikeda, Tomohiko Shindo, Yoku Kikuchi, Kiyotaka Hao, Takashi Shiroto, Jun Takahashi, Satoshi Miyata, Yasuhiko Sakata, Kei Takase, Masahiro Kohzuki, Hiroaki Shimokawa, Tohoku Univ Graduate Sch of Med, Sendai, Japan

3:55 PM

Q & A

4:00 PM

Effect of High Intensity Interval Training on Extracellular Matrix-regulating Enzymes in Women With Breast Cancer Receiving Anthracycline-based Chemotherapy

**Kyuwan Lee** , Univ of Southern California, Los Angeles, CA; Christina Dieli-Conwright, City of Hope, Duarte, CA

4:10 PM

Q & A

4:15 PM

High Intensity Interval Training Does Not Improve Longitudinal Cardiac Motion During Systole or Early Diastole

**Vivek Koshti** , Univ of Texas Southwestern, Dallas, TX; James Patrick Macnamara, UT Southwestern, Dallas, TX; Katrin Dias, Christopher Hearon, IEEM, Dallas, TX; Erin Howden, Baker Heart and Diabetes Inst, Melbourne, Australia; Justin Lawley, Inst of Exercise and Environmental Med, Dallas, TX; Mildred A Opondo, Texas Health Presbyterian Hosp, Dallas, TX; William K Cornwell II, Univ of Colorado Anschutz Med, Aurora, CO; Douglas Stoller, Univ of Texas Southwestern, Dallas, TX; Marcus Anthony Urey, UC San Diego Medical Ctr, La Jolla, CA; Benjamin Levine, Inst of Exercise and Environmental Med, Dallas, TX; Satyam Sarma, IEEM UTSW, Dallas, TX

4:25 PM

Q & A

4:30 PM

Glycine Levels are Associated With Improvements in Submaximal Blood Pressure Response After Endurance Exercise Training

**Jeremy M Robbins** , Bennet Peterson, Jordan Morningstar, Beth Israel Deaconess Medical Ctr, Boston, MA; Tuomo Rankinen, Pennington Biomed Res Ctr, Baton Rouge, LA; Mark A Sarzynski, Univ of South Carolina, Columbia, SC; Claude Bouchard, Pennington Biomed Res Ctr, Baton Rouge, LA; Robert E Gerszten, Beth Israel Deaconess Medical Ctr, Boston, MA

4:40 PM

Q & A

4:55 PM

Q & A

# Abstract Oral Session

## EA.AOS.468 - Issues in Atrial Ablation Management

#### 113A

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Patterns of Very Late Recurrence of Atrial Fibrillation Detected by Continuous Electrocardiographic Monitoring Using an Implantable Loop Recorder

**Nicolle S Milstein** , Suneet Mittal, Jacqueline Pimienta, Advay Bhatt, Tina C. Sichrovsky, Mark W. Preminger, Laura Flynn, Richard E. Shaw, Dan L. Musat, The Valley Hosp, Ridgewood, NJ

3:55 PM

Q & A

4:00 PM

Locations of Recovery of Conduction With the High Power Short Duration Approach in Radiofrequency Catheter Ablation for Atrial Fibrillation

**Sanghamitra Mohanty** , Chintan Gautambhai Trivedi, Domenico Giovanni Della Rocca, Carola Gianni, Ugur Canpolat, Bryan MacDonald, John D Burkhardt, Javier Sanchez, Patrick Hranitzky, Joe Gallinghouse, Amin Al-ahmad, Rodney Horton, Texas Cardiac Arrhythmia Inst, Austin, TX; Luigi Di Biase, 400 Central Park West Apt 9G, New York, NY; Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

4:10 PM

Q & A

4:15 PM

Ablation of Sites That Control Large Areas During Atrial Fibrillation Cause Acute Termination

**Albert J Rogers** , Stanford Univ, Stanford, CA; Neal K Bhatia, Emory Univ, Atlanta, GA; Mahmood Alhusseini, Stanford Univ, Palo Alto, CA; Nosheen F Moosvi, Stanford Univ, Stanford, CA; Tina Baykaner, Stanford Univ, Palo Alto, CA; Chad Brodt, Paul Clopton, Paul J Wang, Stanford Univ, Stanford, CA; Wouter-Jan Rappel, UC San Diego, La Jolla, CA; Sanjiv M Narayan, Stanford Med, Stanford, CA

4:25 PM

Q & A

4:30 PM

Is Cessation of Anticoagulation Safe Post Successful AF Ablation: Late Occurrence of Thromboembolic Events

**Melissa E Middeldorp** , Adrian Elliott, Dennis H Lau, Univ of Adelaide, Adelaide, Australia; Prashanthan Sanders, Univ of Adelaide, Norwood, Australia

4:40 PM

Q & A

4:45 PM

Changes in Cognitive Function in Patients With versus Without Occlusion of the Left Atrial Appendage: Results From A Pilot Study

**Sanghamitra Mohanty** , Chintan G Trivedi, Bryan MacDonald, Shannon Perez Vazquez, Domenico Giovanni Della Rocca, Carola Gianni, Ugur Canpolat, Joe Gallinghouse, Amin Al-Ahmad, Rodney Paul Horton, Mohammed Bassiouny, Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

4:55 PM

Q & A

# Abstract Oral Session

## MP.AOS.547 - Metabolism: PSSST It's Not Just About ATP

#### 120B

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Adam R Wende, Birmingham, AL

3:45 PM

Moderator

Sihem Boudina, Salt Lake Cty, UT

3:45 PM

Klotho Attenuates Hyperglycemia-Induced Cardiac Hypertrophy and Dysfunction by Concomitantly Activating Nrf2 and Brg1

**Yue Guo** , The First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China; Jing Zou, The First Affiliated Hosp, Jinan Univ, Guangzhou, China; Lingling Wu, Mount Sinai St Luke's and West, New York, NY; Xiaodong Zhuang, Xinxue Liao, The First Affiliated Hosp of Sun Yat-Sen Univ, Guangzhou, China

3:55 PM

Q & A

4:00 PM

Deficiency of Sirtuin3 Disrupts Endothelial Glucose Metabolism and Sensitizes Pressure Overload-Induced Heart Failure

**Jian-Xiong Chen** , Heng Zeng, Rebecca A. Worsham, Univ Mississippi Medical Ctr, Jackson, MS; Xiaochen He, UMMC, Jackson, MS

4:10 PM

Q & A

4:15 PM

FOXO1 Increases CardiοMyocyte KLF5 Expression, Which Induces Oxidative Stress, Lipotoxicity and Cardiomyopathy in Type 1 Diabetes

**Ioannis D Kyriazis** , Matthew Hoffman, Temple Univ, Philadelphia, PA; Lea Gaignebet, Charité – Univsmedizin Berlin, Berlin, Germany; Thomas D Bannister, The Scripps Res Inst, Jupiter, FL; Melpo Christofidou-Solomidou, Univ of Pennsylvania, Philadelphia, PA; Ira J Goldberg, New York Univ, New York, NY; Vincent W Yang, Agnieszka B Bialkowska, Stony Brook Univ, Stony Brook, NY; Georgios Kararigas, Charite Univ Hosp, Berlin, Germany; Konstantinos Drosatos, LKSM at Temple Univ, Philadelphia, PA

4:25 PM

Q & A

4:30 PM

Intermittent Fasting Improves Survival In Lipotoxic Cardiomyopathy By Attenuating Protein Aggregate Pathology

**Ali Javaheri** , Layla Foroughi, Xiu Ma, Washington Univ in St Louis, Saint Louis, MO; Kartik Mani, Washington Univ, Clayton, MO; Kenneth B Margulies, Univ Pennsylvania Sch of Med, Philadelphia, PA; Abhinav Diwan, Washington U Sch Med, St Louis, MO

4:40 PM

Q & A

4:45 PM

Ablation of AT2 Receptor Prevents eNOS Uncoupling in Ischemic Abductor Muscle of Diabetic Mice

**Clément Mercier** , Stéphanie Robillard, Valérie Breton, Pedro Miguel Geraldes, Farah Lizotte, Univ of Sherbrooke, Sherbrooke, QC, Canada

4:55 PM

Q & A

# Abstract Oral Session

## QU.AOS.520 - QCOR's Got Talent - High Impact Oral Abstracts: Costs and Resources

#### 202AB

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Real-world Impact of a Novel Digital Medicine Program on Clinical Outcomes and Total Healthcare Costs in Patients With Drug-refractory Hypertension, Diabetes, and/or Hyperlipidemia

Xue Wang, Maxfield Frohlich, Proteus Digital Health, Redwood City, CA; Lindsey Valenzuela, Desert Oasis Healthcare, Palm Springs, CA; Cheri Sacks, R. Scooter Plowman, Proteus Digital Health, Redwood City, CA; **Teresa Hodgkins** , Desert Oasis Healthcare, Palm Springs, CA

3:55 PM

Q & A

4:00 PM

Burden and Consequences of Financial Hardship From Medical Bills Among Non-Elderly Adults With Diabetes Mellitus in The United States

**Cesar Caraballo** , Yale Sch of Med, New Haven, CT; Javier Valero-Elizondo, Yale Univ, New Haven, CT; Rohan Khera, UT Southwestern Medical Ctr, Dallas, TX; Shiwani Mahajan, Yale Univ, New Haven, CT; Gowtham Grandhi, MedStar Health Internal Med, baltimore, MD; Salim S Virani, Michael E Debakey VA-Baylor, Bellaire, TX; Harlan M Krumholz, Yale Univ Sch of Med, New Haven, CT; Khurram Nasir, Baptist Health South Florida, New Haven, CT

4:10 PM

Q & A

4:15 PM

Comparison of Financial Toxicity Among Non-Elderly Adults Patients With Cancer and Atherosclerotic Cardiovascular Disease in the United States

Fouad Chouairi, **Javier Valero-Elizondo** , Yale Univ, New Haven, CT; Rohan Khera, UT Southwestern Medical Ctr, Dallas, TX; Gowtham Rama Harsha Grandhi, MedStar Health Internal Med, Baltimore, MD; Salim S Virani, Michael E Debakey VA-Baylor, Bellaire, TX; Nihar R. Desai, Yale Sch of Med, New Haven, CT; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; Ron Blankstein, Brigham and Womens Hosp, Boston, MA; Harlan M Krumholz, Yale Univ Schl Med, New Haven, CT; Khurram Nasir, Baptist Health South Florida, New Haven, CT

4:25 PM

Q & A

4:30 PM

"Cost Needed to Treat": A Prompt Measure for Comparing Coronary Artery Disease Therapies

**Ronen Arbel** , Enis Aboalhasan, Sapir Coll, Sderot, Israel; Ariel Hammerman, Clalit Health Services, Tel Aviv, Israel; Joseph Azuri, Tel Aviv Univ, Tel Aviv, Israel

4:40 PM

Q & A

4:45 PM

Patients With Acute Myocardial Infarction Discharged on Comfort Measures Only

**Leila Haghighat** , Yale New Haven Hosp, New Haven, CT; Danielle Saly, Brigham and Women's Hosp, Boston, MA; Di Lu, Roland Matsouaka, Leo Brothers, Tracy Y Wang, Duke Clinical Res Inst, Durham, NC; Nihar R. Desai, Yale Sch of Med, New Haven, CT

4:55 PM

Q & A

# Abstract Oral Session

## VA.AOS.578 - Rewriting the Playbook for Peripheral Artery Disease Therapy: Scientific Pathways to Improved Patient Outcomes

#### 103C

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Christina L Fanola, Boston, MA

3:45 PM

Effect of Alirocumab on Peripheral Artery and Venous Thromboembolic Events, and Relation to Lipoprotein(a) Concentration

**Gregory G Schwartz** , Univ of Colorado Sch of Med, Aurora, CO; Philippe Gabriel Steg, Hop Bichat, Paris, France; Michael Szarek, State Univ of New York, Brooklyn, NY; Vera A Bittner, Univ of Alabama at Birmingham, Birmingham, AL; Rafael Diaz, Estudios Clínicos Latinoamérica, Rosario, Argentina; Shaun Geoffrey Goodman, St. Michael's Hosp, Toronto, ON, Canada; Corinne Hanotin, Sanofi, Paris, France; Robert A Harrington, Stanford Univ, Stanford, CA; J Wouter Jukema, Leiden Univ Medical Ctr, Leiden, Netherlands; Alexia Letierce, Sanofi, Paris, France; Robert Pordy, Regeneron Pharmaceuticals, Tarrytown, NY; Matthew T Roe, Duke Clinical Res Inst, Durham, NC; Harvey D White, Auckland City Hosp, Auckland, New Zealand; Andreas M Zeiher, Goethe Univ, Frankfurt Am Main, Germany; Deepak L Bhatt, Brigham and Women's Hosp Heart & Vascular Ctr, Boston, MA; for the ODYSSEY OUTCOMES Investigators

3:55 PM

Q & A

4:00 PM

A Randomized Trial of Low-Dose Methotrexate for the Prevention of Peripheral Artery Disease

**Aruna D Pradhan** , Brigham and Women's Hosp, Boston, MA; Aaron W Aday, Vanderbilt Univ Medical Ctr, Nashville, TN; Elaine Zaharris, Jean MacFadyen, Jeremy Lema-Driscoll, Nancy R Cook, Paul M Ridker, Brigham and Women's Hosp, Boston, MA

4:10 PM

Q & A

4:15 PM

Anticoagulation Does Not Reduce the Risk of Major Adverse Limb Events After Index Peripheral Endovascular Intervention

**Niveditta Ramkumar** , The Dartmouth Inst, Lebanon, NH; Philip P Goodney, Mark A Creager, Stanislav Henkin, Dartmouth-Hitchcock Medical Ctr, Lebanon, NH

4:25 PM

Q & A

4:30 PM

Temporal Changes in Statin Prescription, Intensity at Discharge, and Impact on Outcomes in Patients With Newly Diagnosed Atherosclerotic Peripheral Arterial Disease (PAD). A Real-World Experience Within a Large Integrated Health Care System: The IMPRES Study

**Jeffrey Lance Anderson** , Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT; Kirk Ute Knowlton, Heidi T May, Intermountain Medical Ctr, Salt Lake City, UT; Tami L Bair, Intermountain Medical Ctr, Salt Lake Cty, UT; Viet T LE, Donald L Lappe, Intermountain Medical Ctr, Salt Lake City, UT; Joseph B Muhlestein, Intermountain Medical Ctr; Univ of Utah, Murray, UT

4:40 PM

Q & A

4:45 PM

Cilostazol is Not Associated With Improved Health Status in Patients With Symptomatic Peripheral Arterial Disease

**Moghniuddin Mohammed** , Saint Luke's Hosp, Kansas City, MO; Kensey Gosch, Kim Smolderen, Saint Luke's Mid America Heart Inst, Kansas City, MO

4:55 PM

Q & A

# Abstract Oral Session

## CA.AOS.536 - Thomas Smith Memorial Lecture

#### 120C

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Sarah Franklin, Salt Lake Cty, UT

3:45 PM

Moderator

Peipei Ping, Los Angeles, CA

3:45 PM

Thomas Smith Memorial Lecture

Susan F Steinberg, New York, NY

4:10 PM

Q&A

4:15 PM

Pressure Stress Triggers Src/Focal Adhesion Kinase Complex to Phosphorylate Tyrosine Residue of Cardiac Myosin Binding Protein-C

**Carl Wei-Chan Tong** , Ling Wang, Yixin Jin, Yang Liu, Heidi Creed, Jian Wang, Mariappan Muthuchamy, Xu Peng, Texas A&M Univ Coll of Med, Bryan, TX

4:25 PM

Q&A

4:30 PM

Deficiency of 3-Mercaptopyruvate Sulfurtransferase Results in Impaired Mitochondrial Function and Increased Heart Failure Severity

**Zhen Li** , Huijing Xia, Thomas Sharp III, Hunter Hidalgo, LSU Health Sciences Ctr - NO, New Orleans, LA; Nagahara Noriyuki, Nippon Medical Sch, Tokyo, Japan; John W Elrod, Temple Univ, Philadelphia, PA; David J Lefer, LSU Health Sciences Ctr - NO, New Orleans, LA

4:40 PM

Q & A

4:45 PM

Spliced X-box Binding Protein 1 Promotes Cardiac Fibrosis by Transcriptionally Activating Signal Transducer and Activator of Transcription 3 in Mice

**Zhen-Guo Ma** , Yu-Pei Yuan, Xin Zhang, Qi-Zhu Tang, Renmin Hosp of Wuhan Univ, Wuhan, China

4:55 PM

Q & A

# Abstract Oral Session

## CA.AOS.532 - We Now Return to Our Regularly Scheduled Programming...for Cardiomyocytes

#### 103B

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Joseph Brady Moore IV, Louisville, KY

3:45 PM

Direct Cardiac Reprogramming in Human Cardiac Fibroblasts via Micrornas

**Conrad Hodgkinson** , Richard E Pratt, Duke Univ, Durham, NC; Victor Joseph Dzau, Natl Acad of Med, Washington, DC; Conrad Hodgkinson, Duke Univ, Durham, NC

3:55 PM

Q & A

4:00 PM

The Estrogen-related Receptor Coordinates Transcription of Genes Involved in Mitochondrial and Contractile Maturation in Human Induced Pluripotent Stem Cell-derived Cardiac Myocytes

**Tomoya Sakamoto** , Shibiao Wan, Univ of Pennsylvania, Philadelphia, PA; Junil Kim, Kyoung Jae Won, Univ of Copenhagen, Copenhagen, Denmark; Daniel P Kelly, Univ of Pennsylvania, Philadelphia, PA

4:10 PM

Q & A

4:15 PM

Efficient Large-Scale Purification of Human iPSC-Derived Cardiomyocytes by Synthetic microRNA Switch and Magnetic-Activated Cell Sorting

**Takeshi Hatani** , Chikako Okubo, Yoshihiko Fujita, Kazuhisa Chonabayashi, Kyoto Univ, Kyoto, Japan; Takeshi Kimura, Kyoto Univeristy, Kyoto, Japan; Hirohide Saito, Yoshinori Yoshida, Kyoto Univ, Kyoto, Japan

4:25 PM

Q & A

4:30 PM

Myocardial Tissue Engineer With Cardiomyocytes Derived From Human-induced Pluripotent Stem Cells and Native Decellularized Placenta Scaffold

**Yu Jiang** , The Univ of Hong Kong, Hong Kong, Hong Kong; Zhe Zhen, The Univ of Hong Kong, Hong Kong, China; Songyan Liao, The Univ of Hong Kong, Hong Kong, Hong Kong; Hung-Fat Tse, The Univ of Hong King, Hong Kong

4:40 PM

Q & A

4:45 PM

Identification of a Cell Surface Marker Which is Differentially Expressed Between Ventricular and Atrial Cardiomyocytes Derived From Human Induced-Pluripotent Stem Cell

**Misato Koakutsu** , CiRA, Kyoto Univ, Kyoto, Japan; Kenji Miki, CiRA Kyoto Univ, Kyoto, Japan; Masako Sasaki, CiRA, Kyoto Univ, Kyoto, Japan; Stephanie Napier, Takeda Pharmaceutical Company Limited, Fujisawa, Japan; Tomoyuki Nishimoto, Takeda Pharmaceutical Company, Osaka, Japan; Yoshinori Yoshida, Kyoto Univ, Kyoto, Japan

4:55 PM

Q & A

# Cardiovascular Seminar

## AC.CVS.560 - ACS Networking Session

#### Terrace Ballroom IV

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

George D Dangas, New York, NY

3:45 PM

Moderator

Navin K KAPUR, Hanover, MA

3:45 PM

Invited Presenter: Roundtable Expert - Pharmacotherapy

Deepak L. Bhatt, Newton, MA

3:45 PM

Invited Presenter: Roundtable Expert - Pharmacotherapy

Timothy D Henry, Cincinnati, OH

3:45 PM

Invited Presenter: Roundtable Expert - Interventional Approach

Ajay Kirtane, New York, NY

3:45 PM

Invited Presenter: Roundtable Expert - Hemodynamic Support in Cardiogenic Shock

Behnam Tehrani, Falls Church, VA

3:45 PM

Invited Presenter: Roundtable Expert - Hemodynamic Support in Cardiogenic Shock

Holger Thiele, Leipzig

3:45 PM

Invited Presenter: Roundtable Expert - Timing of Shock Intervention

Manreet Kanwar, Pittsburgh, PA

# Cardiovascular Seminar

## IM.CVS.342 - Aortic Dissection: New Insights

#### 108B

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Thomas Gleason, Pittsburgh, PA

3:45 PM

Moderator

Kim A Eagle, Ann Arbor, MI

3:45 PM

Limited Intimal Tears of the Aorta (Case)

Anne S Chin, Montreal, QC, Canada

4:00 PM

Intramural Hematoma Revisited (Case)

Lewis Hahn, CA

4:15 PM

Insights From MRI and CFD

Nicholas BURRIS, Ann Arbor, MI

4:30 PM

Predicting Late Complications in Type B Aortic Dissection

Martin J Willemink, Menlo Park, CA

4:45 PM

Chronic Dissection and Surveillance

Dominik Fleischmann, Stanford, CA

# Cardiovascular Seminar

## WS.CVS.263 - Cardiovascular Treatment Decisions in the Very Elderly

#### 117

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Adam Gepner, WI

3:45 PM

Moderator

Karol E Watson, Los Angeles, CA

3:45 PM

How Does Biologic Age Differ From Chronologic Age in Treatment Decisions?

Sarah Goodlin, Portland, OR

4:00 PM

Statin Therapy in the Very Elderly: Heart Disease vs. Dementia?

Daniel Duprez, Minneapolis, MN

4:15 PM

Antihypertensive Therapy in the Very Elderly: Risk Reduction vs. Frailty?

Keith C Ferdinand, New Orleans, LA; Keith C Ferdinand, New Orleans, LA

4:30 PM

Atrial Fibrillation in the Very Elderly and Dilemma of Anticoagulation

Veronique L Roger, Rochester, MN

4:45 PM

CAD in the Very Elderly: Medical vs Interventional Therapy

Frans VAN DE WERF, Leuven, Belgium

# Cardiovascular Seminar

## CH.CVS.422 - Controversies in Health Policy for Congenital Heart Disease

#### 111AB

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Sara K PASQUALI, Ann Arbor, MI

3:45 PM

Moderator

James W Gaynor, Philadelphia, PA

3:45 PM

STS Public Reporting: Where We've Been and Where We're Going

John Mayer, Boston, MA

4:15 PM

Are There Too Many Congenital Heart Centers? The Role of Professional Societies

Carl Lewis L Backer, Chicago, IL

4:30 PM

Simulating Regionalization: Potential Impacts on Programs, Outcomes, and Patient Travel

Tara Karamlou, Cleveland, OH

4:45 PM

Sharing Best Practices to Improve Outcomes - Can We Really Get Centers to Collaborate?

Michael G Gaies, Ann Arbor, MI

# Cardiovascular Seminar

## EA.CVS.56 - Controversies Involving Genetic Arrhythmia Syndromes

#### 113BC

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Lee L Eckhardt, Madison, WI

3:45 PM

Moderator

Barry London, Iowa City, IA

3:45 PM

Does ICD Therapy Have Any Role in CPVT?

Marco Perez, Palo Alto, CA

3:50 PM

Q&A

4:00 PM

The Athlete With SCA

Rachel Lampert, New Haven, CT

4:05 PM

Q&A

4:15 PM

Brugada Syndrome: Risk Stratification

Steve Lubitz, Boston, MA

4:20 PM

Q&A

4:30 PM

Is There a Time for ICD Explant in LQTS?

Ben Shoemaker, Nashville, TN

4:35 PM

Q&A

4:45 PM

Challenges in Acquired Long QT Syndrome

Elizabeth Kaufman, Clevland, OH

4:50 PM

Q&A

3:45 PM

Panel Participant

Marina Cerrone, New York, NY

3:45 PM

Panel Participant

Joseph E Marine, Baltimore, MD

3:45 PM

Panel Participant

Peter F Aziz, Cleveland, OH

# Cardiovascular Seminar

## SA.CVS.359 - Current Concepts in Hypertrophic Cardiomyopathy

#### 109AB

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Diana anca, New York, NY

3:45 PM

Moderator

Abe Deanda, TX

3:45 PM

Genetic Screening and Familial Penetrance

Anjali Tiku Owens, Philadelphia, PA

4:00 PM

Precision Medicne: Novel Medical Therapies for HCM

Matthew T Wheeler, Stanford, CA

4:15 PM

Sugical Planning With 3D Modeling for HCM

Hiroo Takayama, New York, NY

4:30 PM

Surgery for HCM: Is it a Long-Term Fix?

Pavan Atluri, Philadelphia, PA

4:45 PM

Intraoperative Monitoring and How to Confirm Successful Myectomy

Kent H Rehfeldt, Rochester, MN

# Cardiovascular Seminar

## CA.CVS.396 - Emerging Concepts in HFpEF

#### 119AB

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Traci T Goodchild

3:45 PM

Moderator

Flora Sam, Boston, MA

3:45 PM

What is HFpEF?

Blanche Schroen, Maastricht, Netherlands Antilles

3:55 PM

Q&A

4:00 PM

Novel Animal Models of HFpEF

Steven Houser, Philadelphia, PA

4:10 PM

Q&A

4:15 PM

Myocyte Calcium Handling in HFpEF vs HFrEF

Eduardo Marban, Los Angeles, CA

4:25 PM

Q&A

4:30 PM

Right Heart Dysfunction in HFpEF

Margaret M Redfield, Rochester, MN

4:40 PM

Q&A

4:45 PM

HFpEF or Not?

Rosanne Rouf, Baltimore, MD

4:55 PM

Q&A

# Cardiovascular Seminar

## NR.CVS.270 - Frailty in CVD Patients: An Important Clinical Conundrum

#### 118C

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Jon AULD, Seattle, WA

3:45 PM

Frailty in CVD Explained: Pathophysiology, Clinical Significance and Assessment

Patricia Davidson, Baltimore, MD

3:55 PM

Geriatrics and Heart Failure: How and When Frailty Intersects With Heart Failure

Quin E Denfeld, Portland, OR

4:05 PM

Frailty and LVADs: Can Frailty Be Reversed?

Victoria Dickson, New York, NY

4:15 PM

Frailty: What Do Physical Performance Measures Tell Us?

Rebecca Gary, Commerce, GA

4:25 PM

Prevention is the Key: Now What Do I Do to Prevent Frailty in My Patient With CVD

Gordon R Reeves, Philadelphia, PA

4:35 PM

Panel Discussion

# Cardiovascular Seminar

## AT.CVS.297 - Frontiers in Cardiovascular Target Discovery

#### 126B

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Masanori Aikawa, Boston, MA

3:45 PM

Moderator

Zorina Galis, Bethesda, MD

3:45 PM

Systems Approach to Target Discovery for Vascular Disease

Masanori Aikawa, Boston, MA

3:55 PM

Q&A

4:10 PM

Q&A

4:15 PM

Comprehensive Integration of Single Cell Analysis Data

Joseph C Wu, Stanford, CA

4:25 PM

Q&A

4:30 PM

Genomics and microRNAs in Target Discovery

Katey Rayner, Ottawa, ON, Canada

4:40 PM

Q&A

4:45 PM

An O-PTM Atlas to Understanding Oxidative Stress in Heart Failure

Peipei Ping, Los Angeles, CA

4:55 PM

Q&A

# Cardiovascular Seminar

## AT.CVS.230 - Frontiers in Vascular Regeneration

#### 126A

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Ngan F Huang, Stanford, CA

3:45 PM

Moderator

Luke Brewster, Emory, GA

3:45 PM

miRNAs for Induction of Vascular Regeneration

Hanjoong Jo, Atlanta, GA

3:55 PM

Q&A

4:00 PM

Biomaterials Approach to Modulate Endothelial-to-Mesenchymal Transition for Vascular Regeneration

Ngan F Huang, Stanford, CA

4:10 PM

Q&A

4:15 PM

Immunomodulation of Stem Cell Therapy for Treatment of PAD

KATHERIN Leckie, Indianapolis, IN

4:25 PM

Q&A

4:30 PM

Application of Chemically Modified mRNAs for Vascualr Regeneration

Lior Zangi, New York, NY

4:45 PM

Q&A

4:50 PM

Molecular Imaging in Peripheral Vascular Disease and Vascular Grafts

Mitchel Stacy, Columbus, OH

# Cardiovascular Seminar

## CH.CVS.721 - Identification of Unexpected Heart Disease in Children: An Update on School Heart Screening and Neonatal Screening

#### 112AB

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Shelley D Miyamoto, Aurora, CO

3:45 PM

Update on School Screening: Japan

Mamoru Ayusawa, Tokyo, Japan

4:00 PM

Update on School Screening, USA:

Justin Zachariah, TX

4:15 PM

Update on Neonatal Screening: Japan

Masao Yoshinaga, Kagoshima, Japan

4:30 PM

Update on Neonatal Screening: USA

Matthew Oster, Atlanta, GA

4:45 PM

Discussion

# Cardiovascular Seminar

## AT.CVS.101 - Moving up the Ranks: Assistant to Full Professor and Beyond?

#### 121C

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Panel Participant

Yabing Chen, Birmingham, AL

3:45 PM

Panel Participant

Kerry-anne Rye, Sydney, Australia

3:45 PM

Panel Participant

Alan Daugherty, Lexington, KY

3:45 PM

Panel Participant

Steven R Lentz, Iowa City, IA

# Cardiovascular Seminar

## PH.CVS.565 - New Horizons in the Modeling of Pulmonary Vascular Disease

#### 102AB

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Werner Seeger, Giessen

3:45 PM

Moderator

Paul B Yu, Boston, MA

3:45 PM

Moderator

Hyung J Chun, New Haven, CT

3:45 PM

Tissue-Informed Engineering Strategies for Modeling Human PH

Chelsea Magin, Aurora, CO

4:00 PM

Ex-vivo Lung Perfusion of PH Lungs: Novel Precision Medicine Approach

Evangelos D Michelakis, Edmonton, AB, Canada

4:15 PM

Precision Cut Lung Slices Reveal Novel Pulmonary and Pulmonary Vascular Biology

Xingbin Ai, Boston, MA

4:30 PM

Rapid 3D Bioprinting for Vascular Tissue Engineering

Shaochen Chen, La Jolla, CA

4:45 PM

Panel Discussion

# Cardiovascular Seminar

## CS.CVS.102 - Paul Dudley White International Lecture and Session

#### Nutter Theatre

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Robert A Harrington, Stanford, CA

3:45 PM

Paul Dudley White International Lecture: Enhancing Cardiovascular Care: Global Collaboration is How it Happens

Paul W Armstrong, Edmonton, AB, Canada

4:15 PM

Fireside Chat

Christopher Bull Granger, Durham, NC

4:15 PM

Fireside Chat

Cynthia M Westerhout, Edmonton, AB, Canada

4:15 PM

Fireside Chat

Padma Kaul, Edmonton, AB, Canada

4:15 PM

Fireside Chat

Frans J VAN DE WERF, Leuven, Belgium

4:45 PM

Audience Q & A

# Cardiovascular Seminar

## EP.CVS.522 - The Epidemiology of High Value Care: An Economic Perspective

#### 201C

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Ambarish Pandey, Dallas, TX

3:45 PM

Moderator

Norrina B ALLEN, Chicago, IL

3:55 PM

Role of Lifestyle Risk Factor Modification in Reducing Long Term Health Care Cost: From Physical Fitness to Financial Fitness

Jarett D Berry, Dallas, TX

4:05 PM

Reducing Cardiovascular Health Care Cost Without Causing Harm: Is it Possible?

Muthiah Vaduganathan, Boston, MA

4:15 PM

Wealth Shock & Financial Toxicity: The HealthCare Emergencies in the Current Era

Lindsay Pool, Chicago, IL

4:25 PM

Lowering Blood Pressure to Lower the Cost of Care: The SPRINT Experience

Adam P Bress, Salt Lake City, UT

4:45 PM

The Soaring Cost of High Value Care in the Current Era: The PCSK9 Experience

Dhruv S. Kazi, Boston, MA

4:55 PM

Q & A

# Featured Science

## FS.AOS.07 - Outpatient Strategies for Heart Failure Management

#### 103A

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Jane E Wilcox, Chicago, IL

3:45 PM

Motivational Interviewing Effectively Improves Self-Care in Patients With Heart Failure: Results of the Motivate-HF Randomized Clinical Trial

**Ercole Vellone** , Univ of Rome Tor Vergata, Rome, Italy; Paola Rebora, Davide Ausili, Univ of Milan-Bicocca, Vedano Al Lambro - Milan, Italy; Valentina Zeffiro, Gianluca Pucciarelli, Stefano Masci, Rosaria Alvaro, Univ of Rome Tor Vergata, Rome, Italy; Barbara J Riegel, Univ Pennsylvania, Philadelphia, PA

3:53 PM

Discussion

3:56 PM

Effect of Patient-Centered Transitional Care Services in Patients Hospitalized for Heart Failure: Clinical and Sex Specific Outcomes of the PACT-HF Randomized Clinical Trial

**Harriette G. C. Van Spall** , Shun Fu Lee, Population Health Res Inst, Hamilton, ON, Canada; Feng Xie, McMaster Univ, Hamilton, ON, Canada; Urun Erbas Oz, Richard Perez, Inst for Clinical Evaluative Sciences McMaster, Hamilton, ON, Canada; Lehana Thabane, MC Master Univ, Hamilton, ON, Canada; Kim D Simek, Population Health Res Inst, Hamilton, ON, Canada; Dennis T Ko, Inst for Clinical Evaluative Sciences, Toronto, ON, Canada; Stuart J Connolly, MC Master Univ, Hamilton, ON, Canada

4:04 PM

Discussion

4:07 PM

Remote Patient Management Reduces Mortality in Heart Failure Patients With Atrial Fibrillation: Insights From the TIM-HF2 Trial

**Tina Stegmann** , Univsklinikum Leipzig, Leipzig, Germany; Kerstin Koehler, Charite Universtitätsmedizin Berlin, Berlin, Germany; Rolf Wachter, Univsklinikum Leipzig, Leipzig, Germany; Volker Moeller, Charité – Univsmedizin- Berlin, Berlin, Germany; Samira Zeynalova, Univ Leipzig, Leipzig, Germany; Friedrich Koehler, Charité – Univsmedizin- Berlin, Berlin, Germany; Ulrich Laufs, Univsklinikum Leipzig, Leipzig, Germany

4:15 PM

Discussion

4:18 PM

Pulmonary-Artery-Pressure-Guided Therapy for Ambulatory Heart Failure Patients in Clinical Practice in Europe - The Prospective MEMS-HF Study

**Christiane Angermann** , Univ Hosp Würzburg, Würzburg, Germany; Birgit Aßmus, Goethe Univ Hosp, Frankfurt, Germany; Stefan D Anker, Charité Univ Med Berlin, Berlin; Johannes Brachmann, Klinikum Coburg, Coburg; Georg Ertl, Univ Hosp Würzbur, Wuerzburg, Germany; Friedrich Köhler, Charité – Univsmedizin Berlin, Berlin, Germany; Stephan Rosenkranz, Univ of Cologne, Cologne; Jasper Brugts, Erasmus MC Univ Medical Ctr, Rotterdam, Netherlands; Folkert W Asselbergs, Univ Medical Ctr Utrecht, Utrecht, Germany; Lutz Hilker, Klinikum Karlsburg, Karlsburg, Germany; Qian Zhou, Heart Ctr, Univ Freiburg, Freiburg; Marie-Elena Brett, Abbott, Burlington, MA; Greg Ginn, Abbott, Atlanta, GA; Philip Adamson, Abbott, Austin, TX; Michael Boehm, Univsklinikum des Saarlandes, Homburg

4:26 PM

Discussion

4:29 PM

Proactive Heart Failure Management Incorporating Ambulatory Pulmonary Artery Pressure Monitoring With the Cordella Heart Failure System: Results of the SIRONA First-in-Human Study

**Wilfried Mullens** , Ziekenhuis Oost-Limburg, Genk, Belgium; Faisal Sharif, Regenerative Med Inst, Galway; Matthias Dupont, Ziekenhuis Oost-Limburg, Genk, Belgium; Alex M Rothman, Univ of Sheffield, Sheffield, Germany; William Wijns, NUI Galway, Galway, Ireland

4:37 PM

Discussion

4:40 PM

Navigator-Led Remote Optimization of Guideline-Directed Medical Therapy in Patients With Heart Failure With Reduced Ejection Fraction

**Akshay S Desai** , Taylor MacLean, Joshua Bosque-Hamilton, Jacqueline Dunning, Christina Fischer, Liliana Fera, Katelyn Vautrin-Smith, Kavishwar Wagholikar, David Zelle, Thomas Andrew Gaziano, Benjamin M Scirica, Calum MacRae, Brigham and Women's Hosp, Boston, MA

4:48 PM

Discussion

4:50 PM

An Experimental Evaluation of the Contrasting Association Between the Hospital Readmissions Reduction Program and Mortality Among Patients With Heart Failure

**Rohan Khera** , UT Southwestern Medical Ctr, Dallas, TX; Yongfei Wang, Yale Univ Sch of Med, Cheshire, CT; Susannah Bernheim, Yale/YNHH Core, New Haven, CT; Zhenqiu Lin, Yale-New Haven Hosp, New Haven, CT; Sharon-Lise T Normand, Harvard Medical Sch, Boston, MA; Harlan M Krumholz, Yale Univ Sch of Med, New Haven, CT

4:58 PM

Discussion

# Hybrid

## CM.HB.569 - Examining Effects of Novel Therapeutic Agents in Diabetes

#### 204AB

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Risk of Amputation Associated With Sodium-Glucose Co-Transporter 2 Inhibitors: A Meta-Analysis of Randomized Controlled Trials

**Satoshi Miyashita** , Mount Sinai Beth Israel Medical Ctr, NEW YORK, NY; Toshiki Kuno, Mount Sinai Beth Israel, New York, NY; Hisato Takagi, Shizuoka Medical Ctr, Shizuoka, Japan; Takehiro Sugiyama, NCGM, Tokyo, Japan; Tomo Ando, Detroit Medical Ctr, Detroit, MI; Nelson Valentin, Mount Sinai Beth Israel Medical Ctr, NEW YORK, NY; Yuichi Shimada, CUMC/Presbyterian Hosp and Vanderbilt Clinic, New York, NY; Masaki Kodaira, Japan Red Cross Ashikaga Hosp, Ashikaga, Japan; Yohei Numasawa, Japanese Red Cross Ashikaga Hosp, Ashikaga, Japan; Yumiko Kanei, Beth Israel Medical Ctr, New York, NY; Sripal Bangalore, New York Univ Sch of Med, New York, NY

3:55 PM

Q & A

4:00 PM

Effect of Dapagliflozin on Atrial Fibrillation/Flutter in Patients With Type 2 Diabetes Mellitus: Insights From the DECLARE-TIMI 58 Trial

**Thomas A Zelniker** , TIMI Study Group, Brigham and Women's Hosp and Harvard Medical Sch, Boston, MA; Marc P Bonaca, CPC Clinical Res, Aurora, CO; Ofri Mosenzon, Hadassah Hebrew Univ Hosp, Jerusalem, Israel; Julia F Kuder, Sabina A Murphy, Remo HM Furtado, Deepak L Bhatt, TIMI Study Group, Brigham and Women's Hosp and Harvard Medical Sch, Boston, MA; Lawrence A Leiter, Univ of Toronto, Toronto, ON, Canada; Darren K McGuire, Univ of Texas Southwestern Medical Ctr, Dallas, TX; John PH Wilding, Univ of Liverpool, Liverpool, United Kingdom; Andrzej Budaj, Postgraduate Medical Sch, Warsaw, Poland; Robert Gabor Kiss, Medical Ctr Hungarian Defence Fo, Budapest, Hungary; Francisco Padilla, Cardiología Clínica e Intervencionista Tarascos, Guadalajara, Mexico; Ingrid Ami Gause-Nilsson, Anna Maria Langkilde, AstraZeneca, Mölndal, Sweden; Itamar Raz, Hadassah Hebrew Univ Hosp, Tel Aviv, Israel; Marc S Sabatine, TIMI Study Group, Boston, MA; Stephen D Wiviott, TIMI Study Group, Brigham and Women's Hosp and Harvard Medical Sch, Boston, MA

4:10 PM

Q & A

4:15 PM

Liraglutide and Semaglutide Reduce Cardiovascular Events in Patients With Type 2 Diabetes and Peripheral Arterial Disease

**Subodh Verma** , St. Michael's Hosp; Univ of Toronto, Toronto, ON, Canada; Soren Rasmussen, Hans Askelund Saevereid, Maria Sejersten Ripa, Novo Nordisk A/S, Soborg, Denmark

4:25 PM

Q & A

4:30 PM

Canagliflozin Reduces Cardiovascular and Renal Events in Patients With Type 2 Diabetes and Chronic Kidney Disease Regardless of Baseline HbA1c, Including Those With HbA1c <7%: Results From the CREDENCE Trial

**Christopher P Cannon** , Cardiovascular Div, Brigham & Women's Hosp and Baim Inst for Clinical Res, Boston, MA; Vlado Perkovic, The George Inst for Global Health, UNSW Sydney and The Royal North Shore Hosp, Sydney, Australia; Rajiv Agarwal, Indiana Univ Sch of Med and VA Medical Ctr, Indianapolis, IN; James Baldassarre, Janssen Res & Development, LLC, Raritan, NJ; George L Bakris, Dept of Med, Univ of Chicago Med, Chicago, IL; Barry M Brenner, Renal Div and Dept of Med, Brigham and Women's Hosp, Harvard Medical Sch and Baim Inst for Clinical Res, Boston, MA; David Charytan, Nephrology Div, NYU Sch of Med and NYU Langone Medical Ctr, New York, NY; Dick de Zeeuw, Dept of Clinical Pharmacy and Pharmacology, Univ of Groningen, Univ Medical Ctr Groningen, Groningen, Netherlands; Robert Edwards, Janssen Res & Development, LLC, Raritan, NJ; Tom Greene, Div of Biostatistics, Dept of Population Health Sciences, Univ of Utah, Salt Lake City, UT; Hiddo J Lambers Heerspink, Dept of Clinical Pharmacy and Pharmacology, Univ of Groningen, Univ Medical Ctr Groningen, Groningen, Netherlands; Meg Jardine, The George Inst for Global Health, UNSW Sydney and Concord Repatriation General Hosp, Sydney, Australia; Adeera Levin, Div of Nephrology, Univ of British Columbia, Vancouver, BC, Canada; Jing-Wei Li, The George Inst for Global Health, UNSW Sydney, Sydney, Australia; Bruce Neal, Imperial Coll London, London, UK; The George Inst for Global Health, UNSW Sydney and The Charles Perkins Ctr, Univ of Sydney, Sydney, Australia; Carol Pollock, Kolling Inst of Medical Res, Sydney Medical Sch, Univ of Sydney, Royal North Shore Hosp, St Leonards, Australia; David Wheeler, Dept of Renal Med, UCL Medical Sch, London, United Kingdom; Hong Zhang, Renal Div of Peking Univ First Hosp, Beijing, China; Bernard Zinman, Lunenfeld-Tanenbaum Res Inst, Mt Sinai Hosp, Univ of Toronto, Toronto, ON, Canada; Kenneth W Mahaffey, Stanford Ctr for Clinical Res, Dept of Med, Stanford Univ Sch of Med, Stanford, CA

4:40 PM

Q & A

4:45 PM

Mechanisms of Benefit/Risk for Emerging Therapeutic Agents in Diabetes

Deepak L Bhatt, Boston, MA

4:55 PM

Q & A

# Joint Sessions

## PR.JS.1623 - Care for The Athletic Heart: Many Issues, One Goal: AHA Joint Session with American College of Cardiology

#### 121A

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Richard Kovacs, Indianapolis, IN

3:45 PM

Moderator

Ivor J Benjamin, Milwaukee, WI

3:45 PM

Precision Medicine in Hypertrophic Cardiomyopathies: The Impact of Genetic Diagnosis

Carolyn Ho, Boston, MA

4:00 PM

Q&A

4:03 PM

Exercise in HOCM: What the Data Shows (or Doesn't Show)

Sharlene Day, Philadelphia, PA

4:18 PM

Q&A

4:21 PM

Arrhythmias in Endurance Athletes

Jonathan H Kim, Decatur, GA

4:36 PM

Q&A

4:39 PM

Screening the Young Competitive Athlete: What's Abnormal and What is Not

Rachel J Lampert, New Haven, CT

4:54 PM

Q&A

# Joint Sessions

## IN.JS.380 - Joint AHA/SCAI

#### 107AB

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Sunil V Rao, Durham, NC

3:45 PM

Moderator

Hani Jneid, Houston, TX

3:45 PM

Introduction by Moderators

3:45 PM

Panel Participant

Jacqueline E Tamis-Holland, New York, NY

3:45 PM

Panel Participant

William S Jones, Durham, NC

3:45 PM

Panel Participant

Peter James Mason, Milwaukee, WI

4:00 PM

Panel Discussion

4:06 PM

Use of Mechanical Circulatory Assist Devices in Cardiogenic Shock

Marwan Jumean, Houston, TX

4:18 PM

Panel Discussion

4:24 PM

TAVR Controversies

Mauricio G Cohen, Miami, FL

4:36 PM

Panel Discussion

4:42 PM

Complex Coronary Interventions: Pearls and Pitfalls

Binita Shah, New York, NY

4:54 PM

Panel Discussion

# Main Event

## PR.ME.439 - Gaps in the 2018 Cholesterol Guidelines: The Great Debate(s)

#### Main Event II

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Francine K Welty, Brookline, MA

3:45 PM

Moderator

Neil Stone, Winnetka, IL

3:45 PM

SecondaryPrevention- Icosopent Ethyl

Borge Nordestgaard, Herlev, Denmark

3:52 PM

SecondaryPrevention: EzetimiBe

Christopher Paul Cannon, MD, FAHA, FACC, Boston, MA

3:59 PM

SecondaryPrevention: PCSK9i

Jennifer G ROBINSON, Iowa City, IA

4:06 PM

SecondaryPrevention: SGLT2i

Naveed Sattar, Glasgow

4:13 PM

Primary Prevention: Lifestyle

Carissa Baker-Smith, Baltimore, MD

4:20 PM

Primary Prevention: Lifestyle and Statin

Elaine M URBINA, Cincinnati, OH

4:27 PM

Primary Prevention - CAC - pro

Michael Blaha, Baltimore, MD

4:34 PM

Primary Prevention- CAC -con

Salim Virani, Bellaire, TX

4:48 PM

Panel

# Main Event

## EA.ME.537 - The Future of AF is Now - How Do I Answer My Patients' New Questions?

#### Main Event I

### Sunday, November 17, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Hugh G Calkins, Baltimore, MD

4:15 PM

Can I Ever Get Off These Drugs? Do Antiarrhythmics and Anticoagulants Need To Be Lifelong, or Are There Alternatives?

Anne M Gillis, Calgary, AB, Canada

4:30 PM

Is There Anything I Can Do To Help Myself? Role of Lifestyle and Risk Factor Modification

Christine M Albert, W Hollywood, CA

4:45 PM

Panel Discussion

# Women's Professional Development

## WPD.04 - Gender Differences & Power Structures with the ATVB Women's Leadership Committee

#### Go Red Women in Science & Medicine Lounge, Pennsylvania Convention Center, 2nd Floor, Heart Hub

### Sunday, November 17, 2019, 3:45 PM - 4:30 PM

This is not a CME/CE certified session

# FIT Event

## FIT.06 - What You Need to Know for a Career in Advanced Heart Failure / Transplant Cardiology

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Sunday, November 17, 2019, 3:55 PM - 4:40 PM

This is not a CME/CE certified session

# FIT Event

## FIT.07 - What You Need to Know for a Career in Cardiac Electrophysiology

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Sunday, November 17, 2019, 3:55 PM - 4:40 PM

This is not a CME/CE certified session

# Featured Science

## FS.MDP.04 - A Deeper Dive into Newer Therapies for Heart Failure II

#### Moderated Posters 2, Science and Technology Hall

### Sunday, November 17, 2019, 4:00 PM - 4:50 PM

4:00 PM

Moderator

Larry A Allen, Aurora, CO

4:00 PM

Dapagliflozin Effects on Lung Fluid Volumes in Patients With Heart Failure and Reduced Ejection Fraction: Results From the DEFINE-HF Trial

**Mikhail N Kosiborod** , Michael E Nassif, Sheryl Windsor, Fengming Tang, Saint Luke's Mid America Heart Inst, Kansas City, MO; Mansoor Husain, Univ Health Network, Toronto, ON, Canada; Silvio E Inzucchi, Yale Univ Sch of Med, New Haven, CT; Darren K McGuire, Unvi Texas Southwestern Med Ctr, Dallas, TX; Bertram Pitt, Univ of Michigan, Ann Arbor, MI; Benjamin M Scirica, Brigham and Women's Hosp, Boston, MA; Bethany A Austin, Saint Luke's Mid America Heart Inst, Kansas City, MO; Michael Fong, Univ of Southern California, Los Angeles, CA; Shane LaRue, Washington Univ, St. Louis, MO; Guillermo Umpierrez, Emory Univ, Atlanta, GA; Justin Hartupee, Washington Univ, St. Louis, MO; Yevgeniy Khariton, Ali Malik, Saint Luke's Mid America Heart Inst, Kansas City, MO; Modele O Ogunniyi, Nanette K Wenger, Emory Univ, Atlanta, GA

4:12 PM

Cost-Effectiveness of Tafamidis for Transthyretin Amyloid Cardiomyopathy: A Just-in-Time Analysis Based on the ATTR-ACT Trial

**Dhruv S Kazi** , Richard A. and Susan F. Smith Ctr for Outcomes Res, Boston, MA; Brandon Bellows, Columbia Univ, New York City, NY; Suzanne J Baron, Beth Israel Lahey Health, Boston, MA; Changyu Shen, Richard A. and Susan F. Smith Ctr for Outcomes Res, Boston, MA; David J Cohen, Univ of Missouri-Kansas City, Kansas City, MO; John A Spertus, MID AMERICA HEART INST, Kansas City, MO; Robert W Yeh, Richard A. and Susan F. Smith Ctr for Outcomes Res, Boston, MA; Suzanne V. Arnold, MID AMERICA HEART INST and UMKC, Kansas City, MO; Brett W. Sperry, St. Luke's Mid America Heart Inst, Lees Summit, MO; Mathew S Maurer, New York Presbyterian Hosp, New York, NY; Sanjiv J Shah, Northwestern Univ Feinberg Sch of Med, Chicago, IL

4:24 PM

Vitamin D and Marine Omega-3 Fatty Acid Supplements and Prevention of Heart Failure Hospitalization

**Luc Djousse** , BWH And Harvard Med Sch, Boston, MA; Nancy R Cook, Brigham and Women's Hosp, Boston, MA; Eunjung Kim, Vadim Bubes, BWH, Boston, MA; I-Min Lee, Jacob Joseph, BWH And Harvard Med Sch, Boston, MA; Christine M Albert, Brigham and Women's Hosp, Boston, MA; Julie E Buring, Harvard Medical Sch, Boston, MA; John Michael Gaziano, BWH and Harvard Medical Sch, Boston, MA; Joann E Manson, Harvard Medical Sch, Boston, MA

4:38 PM

Empagliflozin Treatment Substantially Reduces Total Burden of Heart Failure and All-Cause Hospitalizations in Patients With and Without Heart Failure at Baseline

**Stefan D Anker** , Dept of Cardiology (CVK); and Berlin Inst of Health Ctr for Regenerative Therapies (BCRT); German Ctr for Cardiovascular Res (DZHK) partner site Berlin; Charité – Univsmedizin Berlin, Berlin, Germany; Darren K McGuire, Univ of Texas Southwestern Medical Ctr, Dallas, TX; Bernard Zinman, Lunenfeld-Tanenbaum Res Inst, Mount Sinai Hosp, Univ of Toronto, Toronto, ON, Canada; Silvio E Inzucchi, Section of Endocrinology, Yale Univ Sch of Med, New Haven, CT; Christoph Wanner, Wuerzburg Univ Clinic, Wuerzburg, Germany; David Fitchett, St. Michael's Hosp, Div of Cardiology, Univ of Toronto, Toronto, ON, Canada; Stuart Pocock, Dept of Medical Statistics, London Sch of Hygiene & Tropical Med, London, United Kingdom; Stefan Kaspers, Jyothis T George, Boehringer Ingelheim Intl GmbH, Ingelheim, Germany; Odd Erik Johansen, Boehringer Ingelheim Norway KS, Asker, Norway; Waheed Jamal, Boehringer Ingelheim Intl GmbH, Ingelheim, Germany; Ola Vedin, Boehringer Ingelheim AB, Stockholm, Sweden; Ulrich Elsasser, Stefan Hantel, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany; Soeren S Lund, Boehringer Ingelheim Intl GmbH, Ingelheim, Germany

# Featured Science

## FS.MDP.05 - Follow-up of Landmark Trials

#### Moderated Posters 1, Science and Technology Hall

### Sunday, November 17, 2019, 4:00 PM - 4:50 PM

4:00 PM

Moderator

John T Wilkins, Chicago, IL

4:00 PM

The Effects of Anacetrapib on Occlusive Vascular Events During Post-Trial Follow-Up of the REVEAL Randomized Trial

**Emily Sammons** , Univ of Oxford, Oxford, United Kingdom; on behalf of the REVEAL Study Collaborative Group

4:10 PM

Circulating Levels of Small Dense Low-Density Lipoprotein Cholesterol and Cardiovascular Event Risk in Patients With Stable Coronary Artery Disease Treated With High- versus Low-Dose Pitavastatin in the Randomized Evaluation of Aggressive or Moderate Lipid Lowering Therapy With Pitavastatin in Coronary Artery Disease Trial

**Junnichi Ishii** , Fujita Health Univ Sch of Med, Toyoake, Japan; Kosuke Kashiwabara, The Univ of Tokyo, Tokyo, Japan; Hiroshi Takahashi, Hideto Nishimura, Hideki Kawai, Takashi Muramatsu, Masahide Harada, Akira Yamada, Fujita Health Univ Sch of Med, Toyoake, Japan; Mutsuharu Hayashi, Banbuntane Houtokukai Hosp, Nagoya, Japan; Hiroyuki Naruse, Sadako Motoyama, Masayoshi Sarai, Eiichi Watanabe, Fujita Health Univ Sch of Med, Toyoake, Japan; Yutaka Matsuyama, The Univ of Tokyo, Tokyo, Japan; Hideo Izawa, Banbuntane Houtokukai Hosp, Nagoya, Japan; Yukio Ozaki, Fujita Health Univ Sch of Med, Toyoake, Japan; Ryozo Nagai, Jichi Medical Univ, Shimotsuke, Japan

4:20 PM

REDUCE-IT USA: Results From the 3,146 Patients Randomized in the United States

**Deepak L. Bhatt** , Brigham and Women's Hosp, Newton, MA; Philippe Gabriel Steg, Hop Bichat, Paris, France; Michael Miller, Univ of Maryland, Baltimore, MD; Eliot A Brinton, Utah Lipid Ctr, Salt Lake City, UT; Terry A Jacobson, Emory Univ, Atlanta, GA; Steven Ketchum, Amarin Pharma, Inc., Bedminster, NJ; Ralph Doyle, Amarin Pharma Inc., Bedminster, NJ; Rebecca A Juliano, Amarin Pharma Inc, Madison, NJ; Lisa Jiao, Amarin Pharma, Bedminster, NJ; Craig Granowitz, Amarin Pharma Inc., Bedminster, NJ; Jean-Claude Tardif, Montreal Heart Inst, Montreal, QC, Canada; Christie M Ballantyne, Baylor Coll Med, Houston, TX

4:30 PM

Effects of Bariatric Surgery in Patients With Hypertension: 3-Year Outcomes From the Randomized GATEWAY Trial

**Carlos Aurelio Schiavon** , Heart Hosp, São Paulo, Brazil; Deepak L Bhatt, Brigham and Women's Hosp, Boston, MA; Eliana V Santucci, Juliana D Oliveira, Renato N Santos, Lucas P Damiani, Raquel H V Machado, Patricia M Noujaim, Helio Halpern, Frederico L J Monteiro, Heart Hosp, São Paulo, Brazil; Marcio G Sousa, Dante Pazzanese Inst of Cardiology, São Paulo, Brazil; Celso Amodeo, Clinica Cerravel, Sao Paulo, Brazil; Luiz Bortolotto, Heart Inst, São Paulo, Brazil; Dimas T Ikeoka, HCOR Res Inst, Sao Paulo, Brazil; Alexandre B Cavalcanti, Heart Hosp, São Paulo, Brazil; Otavio Berwanger, Albert Einstein Hosp, São Paulo, Brazil; Luciano F Drager, Heart Inst, Sao Paulo, Brazil

4:40 PM

Ten-Year Clinical Outcomes From a Randomized Trial of Polymer-Free Sirolimus- and Probucol-Eluting Stents versus Permanent Polymer Zotarolimus-Eluting Stents in Patients With Coronary Artery Disease

**Sebastian Kufner** , Max Ernst, Salvatore Cassese, Michael Hubert Joner, Deutsches Herzzentrum Munich, Munich, Germany; Tareq Ibrahim, 1. medizinische Klinik, Klinikum Rechts der Isar, Technical Univ Munich, Muenchen, Germany; Tobias Koppara, 1. medizinische Klinik, Klinikum Rechts der Isar, Technical Univ Munich, Munich, Germany; Erion Xhepa, Tobias Koch, Katharina Mayer, Heribert Schunkert, Deutsches Herzzentrum Munich, Munich, Germany; Karl Ludwig Laugwitz, 1. medizinische Klinik, Klinikum Rechts der Isar, Technical Univ Munich, Munich, Germany; Robert A Byrne, Adnan Kastrati, Deutsches Herzzentrum Munich, Munich, Germany

4:45 PM

Discussion

# Featured Science

## FS.MDP.03 - Observational Studies II

#### Moderated Posters 3, Science and Technology Hall

### Sunday, November 17, 2019, 4:00 PM - 4:50 PM

4:00 PM

Moderator

Mark D Huffman, Chicago, IL

4:00 PM

SGLT2i Treatment Reduces Cardiorenal Disease Risk in T2D Patients Without Established Cardiovascular and Renal Diseases: A Large Observational Study

**Issei Komuro** , The Univ of Tokyo, Tokyo, Japan; Johan Bodegard, AstraZeneca, Oslo, Norway; Marcus Thuresson, Statisticon, Uppsala, Sweden; Toshitaka Yajima, AstraZeneca, Chioyda-ku, Japan; Jan W Eriksson, Uppsala Univ Hosp, Uppsala, Sweden; Anna Norhammar, Karolinska Instt, Stockholm, Sweden; Kåre I Birkeland, Univ of Oslo, Oslo, Norway; Takashi Kadowaki, Univ of Tokyo, Tokyo, Japan

4:12 PM

Contrasting Patterns of Risk Factors, Treatments and Outcomes in Women and Men in Those With and Without Prior Cardiovascular Disease in High (H), Middle (M), and Low-Income Countries (LIC)

**Marjan Attaei** , Population Health Res Inst and McMaster Univ, Hamilton, ON, Canada; Philip Joseph, BWH And Harvard Med Sch,, Ancaster, ON, Canada; Annika Rosengren, Sahlgrenska Univ Hosp, Goteborg, Sweden; Sonia Anand, McMaster Univ, Hamilton, ON, Canada; Clara Chow, Univ of Sydney, Westmead, Australia; Salim Yusuf, Population Health Res Inst, Hamilton, ON, Canada; PURE Investigators

4:24 PM

Validation of the Preoperative Cardiovascular Risk Index in Surgical Subpopulations

**Habib A. Dakik** , Eman Sbaity, Ahmad Msheik, Chris Kaspar, Mahmoud Eldirani, Omar Shehab, Ossama Abou Hassan, Aurelie Mailhac, Maha Makki, Hani Tamim, American Univ of Beirut, Beirut, Lebanon

4:38 PM

Heart Rate Variability for the Detection of Myocardial Ischemia in Subjects Without Known Coronary Artery Disease: The HRV-DETECT Study

**Ilan Goldenberg** , Univ of Rochester, Rochester, NY; Ronen Goldkorn, Rafael Kuperstein, Sheba Medical Ctr, Ramat Gan, Israel; Robert Klempfner, Heart Ctr, Sheba Medical Ctr, Ramat Gan, Israel; Nir Shlomo, Michal Einhorn, Sheba Medical Ctr, Ramat Gan, Israel; Courtney Wheatley, Mayo Clinic, Rochester, AZ; Arwa Younis, Bruce David Johnson, Univ of Rochester, Rochester, NY

# Hall

## EA.HT.592 - EP Jeopardy with Audience Play Too

#### Game Central

### Sunday, November 17, 2019, 4:00 PM - 5:00 PM

4:00 PM

Moderator

Paul J Wang, Palo Alto, CA

4:00 PM

Moderator

Melissa R. Robinson, Seattle, WA

4:00 PM

Panel Participant

Jennifer Silva, Saint Louis, MO

4:00 PM

Panel Participant

Julia Indik, AZ

4:00 PM

Panel Participant

Cara Pellegrini, San Francisco, CA

4:00 PM

Panel Participant

William Miles, Gainesville, FL

4:00 PM

Panel Participant

Rakesh Gopinathannair, Louisville, KY

4:00 PM

Panel Participant

Taya V Glotzer, Hackensack, NJ

4:00 PM

Panel Participant

Bryan Baranowski, OH

# FIT Event

## FIT.19 - Early Career/FIT Reception

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Sunday, November 17, 2019, 5:00 PM - 6:30 PM

This is not a CME/CE certified session

# Abstract Oral Session

## ST.AOS.566 - Best of Stroke Abstracts

#### 105AB

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Marijuana Use and Young Onset Stroke: A Cross-Sectional BRFSS Survey Analysis

**Tarang Parekh** , George Mason Univ, Fairfax, VA; Sahithi Pemmasani, Franconia Pediatrics Associates, Alexandria, VA; Rupak Desai, Atlanta VA Medical Ctr, Decatur, GA

5:40 PM

Q & A

5:45 PM

Effect of Low-density Lipoprotein Cholesterol Lowering With Alirocumab on Stroke in ODYSSEY OUTCOMES

**J Wouter Jukema** , Leiden Univ Medical Ctr, Leiden, Netherlands; Michael Szarek, State Univ of New York, Brooklyn, NY; Laurien Zijlstra, Leiden Univ Medical Ctr, Leiden, Netherlands; Deepak L Bhatt, Brigham and Women's Hosp Heart & Vascular Ctr and Harvard Medical Sch, Boston, MA; Vera A Bittner, Univ of Alabama at Birmingham, Birmingham, AL; Rafael Diaz, Estudios Cardiológicos Latinoamérica, Rosario, Argentina; Heinz Drexel, Inselspital Bern, Bern, Switzerland; Shaun Geoffrey Goodman, St. Michael's Hosp, Univ of Toronto, Toronto, ON, Canada; Robert A Harrington, Stanford Ctr for Clinical Res, Stanford, CA; Yong-Un Kim, Sanofi, Paris, France; Michael J Louie, Robert Pordy, Regeneron Pharmaceuticals, Tarrytown, NY; Zeljko Reiner, Univ Hosp Ctr Zagreb, Zagreb, Croatia; Matthew T Roe, Duke Clinical Res Inst, Durham, NC; Hung-Fat Tse, The Univ of Hong Kong, Hong Kong, Hong Kong; Pablo Carlos Montenegro Valdovinos, Unidad de Diagnóstico Cardiológico, Guatemala City, Guatemala; Harvey D White, Green Lane Cardiovascular Services, Auckland City Hosp, Auckland, New Zealand; Andreas M Zeiher, Goethe Univ, Frankfurt Am Main, Germany; Gregory G Schwartz, Univ of Colorado Sch of Med, Aurora, CO; Philippe Gabriel Steg, Hop Bichat, Paris, France; for the ODYSSEY OUTCOMES Investigators

5:55 PM

Q & A

6:00 PM

Bariatric Surgery and Cerebrovascular Outcomes in Patients With Obesity

**Maddalena Ardissino** , Osama Moussa, Tobias Heaton, Alice Tang, Paul Ziprin, Ara Darzi, Imperial Coll London, London, United Kingdom; Omar Khan, St George's Univ Hosp, London, United Kingdom; Peter Collins, Sanjay Purkayastha, Imperial Coll London, London, United Kingdom

6:10 PM

Q & A

6:15 PM

Performance of a Novel Genetic Risk Score to Identify Residual Risk of Ischemic Stroke in Patients Anticoagulated for Atrial Fibrillation

**Nicholas A Marston** , Brigham and Women's Hosp, Boston, MA; Francesco Nordio, Univ of Milan, Milan, Italy; Yared Gurmu, TIMI Study Group, Boston, MA; Carolina Roselli, Broad Inst, Cambridge, MA; Steven A Lubitz, Massachusetts General Hosp, Boston, MA; Robert Giugliano, TIMI Study Group, Boston, MA; Michael A Grosso, Daiichi Sankyo, Basking Ridge, NJ; Michele F Mercuri, Daiichi Sankyo, Scotch Plains, NJ; Hans-Joachim Lanz, Daiichi Sankyo, Munich, Germany; Howard Rutman, Cardiologist, New York, NY; Elliott M Antman, Brigham Womens Hosp, Weston, MA; Eugene Braunwald, Brigham and Women's Hosp, Boston, MA; Marc S Sabatine, TIMI Study Group, Boston, MA; Patrick Thomas Ellinor, Massachusetts General Hosp, Boston, MA; Christian Ruff, Timi Study Group, Boston, MA

6:25 PM

Q & A

6:30 PM

Prevalent Heart Failure and Incident Stroke in Community-Dwelling Older Adults: Insights From 23 Years of Follow-Up in the Cardiovascular Health Study

**Angeliki Filippatou** , Univ of Athens Medical Sch, Athens, Greece; Phillip H Lam, Georgetown Univ, Chevy Chase, MD; Georgios K. Tsivgoulis, Univ of Athens Medical Sch, Athens, Greece; Charles Faselis, VA Medical Ctr, Washington, DC; Richard Allman, Univ of Alabama at Birmingham, Birmingham, AL; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; Ali Ahmed, VA Medical Ctr, Washington, DC

6:40 PM

Q & A

# Abstract Oral Session

## MP.AOS.552 - Cardiovascular, Kidney and Endocrine Interactions: Selected Oral Abstracts

#### 120C

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Jordana Cohen, Philadelphia, PA

5:30 PM

Moderator

James M Luther, Nashville, TN

5:30 PM

Enhanced Expression of Renal Sodium-Glucose Cotransporter 2 (SGLT2) in Rats With Chronic Heart Failure: Role of Renal Nerves

**Kenichi Katsurada** , Univ of Nebraska Medical Ctr, Omaha, NE; Shyam Sundar Nandi, Univ of Nebraska Medical Cent, Omaha, NE; Neeru S Sharma, UNMC, Omaha, NE; Kaushik P Patel, Univ of Nebraska, Omaha, NE

5:40 PM

Q & A

5:45 PM

Activation of AT2 Receptor by NP-6A4 Improves Cardiac Function by Inducing a Novel Cardio-Reparative Protein-Micro RNA Network in Zucker Obese Rats With Untreated Obesity and Diabetes

**Madhavi P. Gavini** , Novopyxis.Inc., Cambridge, MA; Abuzar Mahmood, Anthony M. Belenchia, Paige Beauparlant, Senthil Kumar, Sivakumar Ardhanari, Vincent G DeMarco, Lakshmi Pulakat, Univ of Missouri, Columbia, MO

5:55 PM

Q & A

6:00 PM

Association of Cardiac Parameters With Brain Damage and Cognition in Older Patients With End-Stage Renal Disease

**Laurien Zijlstra** , Stella Trompet, Leiden Univ Medical Ctr, Leiden, Netherlands; J Wouter W Jukema, Leiden Univ Medical Ctr, Leiden, United Kingdom; Lucia Kroft, Jeroen de Bresser, Thijs van Osch, Marjolijn van Buren, Simon Mooijaart, Leiden Univ Medical Ctr, Leiden, Netherlands

6:10 PM

Q & A

6:15 PM

The Long-Term Outcomes in Patients With Chronic Renal Failure on Hemodialysis After Aortic Valve/root Replacement With Stentless Bioprosthesis - 23-year Experience

Aroosa Malik, Linda Farhat, Alexander Makkinejad, Univ of Michigan, Ann Arbor, MI; Elizabeth Norton, Creighton Univ, Omaha, NE; Emma St. Pierre, Univ of Michigan, Ann Arbor, MI; Mohamed Ali Sareini, Wayne State Univ Sch of Med, Detroit, MI; Xiaoting Wu, Francis D Pagani, Univ of Michigan, Ann Arbor, MI; Jonathan Haft, Univ Michigan, Ann Arbor, MI; Matthew A Romano, Univ of Michigan, Ann Arbor, MI; Richard L Prager, Univ Michigan, Ann Arbor, MI; Karen Kim, Univ of Michigan, Ann Arbor, MI; Himanshu J Patel, Univ Michigan Health System, Ann Arbor, MI; G. Michael Deeb, **Bo Yang** , Univ of Michigan, Ann Arbor, MI

6:25 PM

Q & A

6:30 PM

Risk of ASCVD and Non-ASCVD Hospitalizations for Triglycerides Across CKD Stages Among 2 Million US Veterans

Melissa Soohoo, VA Long Beach, Long Beach, CA; Jui-Ting Hsiung, Christina Park, UC Irvine, Orange, CA; Maria Marroquin, VA Long Beach, Long Beach, CA; Hamid Moradi, Long Beach VA Health Care System, Long Beach, CA; Csaba Kovesdy, Univ of Tennessee Health Science Ctr, Memphis, TN; Kamyar Kalantar-Zadeh, Univ of California Irvine, Orange, CA; **Elani Streja** , Univ of California, Irvine, Orange, CA

6:40 PM

Q & A

# Abstract Oral Session

## CA.AOS.539 - George E. Brown Memorial Lecture

#### 119AB

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Joseph C Wu, Stanford, CA

5:30 PM

Moderator

Ronglih Liao, Palo Alto, CA

5:30 PM

George E. Brown Memorial Lecture

Jane E Freedman, Worcester, MA

5:55 PM

Q&A

6:00 PM

Coronary Arteriolar Vasomotor Dysfunction Precedes Cardiac Diastolic Dysfunction in Diabetic Cardiomyopathy

**Carl W Tong** , Heidi A Creed, Shu-Huai Tsai, Lih Kuo, Travis W Hein, Texas A&M Univ Coll of Med, Bryan, TX

6:10 PM

Q&A

6:15 PM

Cyclooxygenase-2 and Heart Failure With Preserved Ejection Fraction

**Emanuela Ricciotti** , Univ of Pennsylvania, Philadelphia, PA; Philip G. Haines, Brown Univ, Providence, RI; Manu Beerens, Uri Kartoun, Harvard Medical Sch, Boston, MA; Nicholas F Lahens, Tao Wang, Univ of Pennsylvania, Philadelphia, PA; Stanley Y Shaw, Calum A. MacRae, Harvard Medical Sch, Boston, MA; Garret A Fitzgerald, Univ of Pennsylvania, Philadelphia, PA

6:25 PM

Q&A

6:30 PM

The Prognostic Utility of a Plasma Ceramide and Phospholipid-Based Risk Score in Patients After Acute Coronary Syndrome

**Baris Gencer** , David A Morrow, Eugene Braunwald, Erica L Goodrich, TIMI Study Group, Boston, MA; Mika Hilvo, Dimple Kauhanen, Zora Biosciences, Espoo, Finland; Marc S Sabatine, TIMI Study Group, Boston, MA; Christopher Paul Cannon, Brigham and Women's Hosp, Boston, MA; Reijo Laaksonen, Zora Biosciences, Espoo, Finland; Michelle L O'Donoghue, TIMI Study Group, Boston, MA

6:40 PM

Q&A

# Abstract Oral Session

## WS.AOS.586 - Go Red for Women: Combatting the Persistent Disparities in Care

#### 117

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Biykem Bozkurt, Houston, TX

5:30 PM

Moderator

Martha Gulati, Phoenix, AZ

5:30 PM

Sex Differences in the Foundations of International Society Heart Failure Practice Guidelines

**Nosheen Reza** , Univ of Pennsylvania, Philadelphia, PA; Ersilia DeFilippis, Columbia Univ, New York City, NY; Nadim Mahmud, Univ of Pennsylvania, Philadelphia, PA; Joann Lindenfeld, Vanderbilt Univ, Nashville, TN; Mariell Jessup, American Heart Association, Hingham, MA

5:40 PM

Q & A

5:45 PM

Sex Differences in Life-Course Neighborhood Racial Composition and Adult Hypertension

**Debbie Barrington** , Georgetown Univ, Washington, DC

5:55 PM

Q & A

6:00 PM

The Impact of Sex on the Outcome and Treatment of Aortic Stenosis Patients

**David Bienjonetti-Boudreau** , Isabelle Chouinard, Geraldine Ong, Mathieu Tailleur, Raphael Duval, Pierre-Olivier Magnan, Marie-Annick Clavel, Ctr de recherche de l'Instutut universitaire de cardiologie et pneumologie de Québec, Québec, QC, Canada

6:10 PM

Q & A

6:15 PM

Representation of Women and Older Patients in Trials of Lipid Lowering Therapy: A Systematic Review

**Safi Ullah Khan** , Muhammad Z Khan, West Virginia Univ, Morgantown, WV; Haris Riaz, Cleveland Clinic, Cleveland, OH; Charumathi Raghu Subramanian, Washington Hosp Health Care System, Fremont, CA; Muhammad Usman Khan, West Virginia Univ, HSC, Morgantown, WV; Ahmad N Lone, West Virginia Univ, Morgantown, WV; Mohammad Shahzeb Khan, John H Stroger Jr Hosp of Cook, Chicago, IL; Mohamad Adnan Alkhouli, West Virginia Univ, Morgantown, WV; Michael J Blaha, Roger S Blumenthal, Roger S Blumenthal, Johns Hopkins Hosp, Baltimore, MD; Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD

6:25 PM

Q & A

6:30 PM

Gender Differences in Cardiovascular Outcomes and Their Association With Risk Factors in Type 2 Diabetic Patients With Established Coronary Artery Disease

**Yuko Fujita** , Univ of the Ryukyus, Nishihara-cho, Japan; Akihiro Tokushige, Kagoshima Univ, Kagoshima, Japan; Takeshi Morimoto, Hyogo Coll of Med, Nishinomiya, Japan; Koichi Node, Saga Univ, Saga, Japan; Shinichiro Ueda, Univ of the Ryukyus, Nishihara-cho, Japan; CHD Cohort Study Group

6:40 PM

Q & A

# Abstract Oral Session

## EA.AOS.469 - New Drug Approaches for Arrhythmia Management

#### 113A

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Wojciech Zareba, Rochester, NY

5:30 PM

Pharmacologic Approach to Treatment of the J Wave Syndromes

**Bence Patocskai** , Heidelberg Univ, Heidelberg, Germany; Virag Anna Borbath, Univ Hosp Mannheim, Mannheim, Germany; Alexander Burashnikov, Lankenau Inst Medical Res, Wynnewood, PA; Gui-Rong Li, Medical Coll of Xiamen, Xiamen, Fujian, China; Charles Antzelevitch, Lankenau Inst for Medical Res, Wynnewood, PA

5:40 PM

Q & A

5:45 PM

Sglt 2 Inhibitor Suppresses Atrial Remodeling of Atrial Fibrillation

**Ryo Nishinarita** , Kitasato Univ Hosp, Sagamihara-shi, Japan; Shinichi Niwano, Kitasato Univ Cardiology, Sagamihara, Japan; Hiroe Niwano, Kitasato Univ, Sagamihara, Japan; Hironori Nakamura, Kitasato Univ Hosp, Kanagawa, Japan; Shuhei Kobayashi, Kitasato Univ, Sagamihara City, Japan; Yuki Shirakawa, Ai Horiguchi, Kitasato Univ, Sagamihara, Japan; Tazuru Igarashi, Kitasato Univ Sch of Med, Sagamihara, Japan; Naruya Ishizue, Kitasato Univ Hosp, sagamihara, Japan; Tamami Fujiishi, Kitasato Univ, Sagamihara, Japan; Tomoharu Yoshizawa, Kitasato Univ, Kanagawa, Japan; Jun Oikawa, Kitasato Univ Hosp, Sagamihara, Japan; Jun Kishihara, Kitasato Univ, Sagamihara, Japan; Hidehira Fukaya, Kitasato Univ Hosp, sagamihara, Japan; Junya Ako, Kitasato Univ, Kanagawa, Japan

5:55 PM

Q & A

6:00 PM

Spironolactone In Patients With Atrial Fibrillation And Preserved Ejection Fraction Does Not Reduce Arrhythmia Burden: Results From A Randomized, Double-blind, Placebo-controlled Trial (INSPIRE-AF)

**Dragana Rujic** , Odense Univ Hosp, Svendborg, Svendborg, Denmark; Manan Pareek, North Zealand Hosp, Hilleroed; Per L Madsen, Flinders Medical Ctr and Flinders Univ, Adelaide, Australia; Kenneth Egstrup, Odense Univ Hosp, Svendborg, Svendborg, Denmark; Tina Juhl Hansen, Copenhagen Univ Hosp Rigshospitalet, Copenhagen, Denmark

6:10 PM

Q & A

6:15 PM

The SK Channel Inhibitors NS8593 and UCL1684 Inhibit Sodium Channel Activity in an Atrial Selective Manner and Prevent Development of Atrial Fibrillation by Depressing Atrial Excitability

**Alexander Burashnikov** , Lankenau Inst Medical Res, Wynnewood, PA; Hector Barajas-Martinez, Lankenau Inst for Medical Res, Wynnewood, PA; Dan Hu, Renmin Hosp of Wuhan Univ, Wuhan, China; Morten Grunnet, Acesion Pharma, Copenhagen, Denmark; Antzelevitch Charles, Lankenau Inst Medical Res, Wynnewood, PA

6:25 PM

Q & A

6:30 PM

Long-Term Outcomes in Patients Treated With Flecainide for Atrial Fibrillation With Stable Coronary Artery Disease

**Thomas Jared Bunch** , Intermountain Medical Ctr, Salt Lake City, UT; Heidi T May, Intermountain Medical Ctr, Murray, UT; Jalisa Cruz, Intermountain Medical Ctr, Salt Lake City, UT; Tami L Bair, Intermountain Medical Ctr, Salt Lake Cty, UT; J. Peter Weiss, John D Day, Brian Crandall, Michael J Cutler, Jeffrey S Osborn, Charles Mallender, Intermountain Medical Ctr, Salt Lake City, UT; Jeffrey Lance Anderson, Intermountain Medical Ctr, Murray, UT; Joseph Brent Muhlestein, Kirk Ute Knowlton, Intermountain Medical Ctr, Salt Lake City, UT

6:40 PM

Q & A

# Cardiovascular Seminar

## PH.CVS.460 - 3CPR: Shark Tank Style

#### Terrace Ballroom IV

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Cameron Dezfulian, Pittsburgh, PA

5:30 PM

Moderator

Stephen Y Chan, Pittsburgh, PA

5:30 PM

Shark

Mark Gladwin, Pittsburgh, PA

5:30 PM

Shark

Marc Semigran, S San Fran, CA

5:30 PM

Shark

Robert W Neumar, Ann Arbor, MI

5:30 PM

Shark

Terry L Vanden Hoek, Chicago, IL

5:30 PM

Shark

Werner Seeger, Giessen, Argentina

5:30 PM

Shark

Jane A Leopold, Boston, MA

5:30 PM

Invited Presenter

Lian Tian, Kingston, ON, Canada

5:41 PM

Invited Presenter

Mohammad Abdul Hai Siddique, Sendai, Japan

5:52 PM

Invited Presenter

Taijya Satoh, Japan

6:03 PM

Invited Presenter

Tulasi Jinka, Ann Arbor, MI

6:14 PM

Invited Presenter

Rajat Kalra, Minneapolis, MN

6:25 PM

Invited Presenter

Alexis madeline Steinberg, Pittsburgh, PA

# Cardiovascular Seminar

## AC.CVS.457 - Challenges in Non ST Elevation ACS

#### 103A

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Roxana Mehran, New York, NY

5:30 PM

Moderator

Stefan K James, Uppsala, Sweden

5:30 PM

Optimal Time Window to Incorporate an Early Invasive Strategy

Shamir R Mehta, Hamilton, ON, Canada

5:40 PM

Discussion

5:45 PM

Approaches to Non Infarct Revascularization: Is There a Right Answer?

Jacqueline E Tamis-Holland, New York, NY

5:55 PM

Discussion

6:00 PM

Novel Biomarkers In NSTEACS: Gaining Pathological and Clinical Insight

James L Januzzi, Wellesley Hills, MA

6:10 PM

Discussion

6:15 PM

Cardiogenic Shock Complicating NSTEACS: Characteristics and Outcome

Erin Bohula, Boston, MA

6:25 PM

Discussion

6:30 PM

Approach to NSTEACS in the Elderly: What Have We Learned

Adam H Skolnick, New York, NY

6:40 PM

Discussion

# Cardiovascular Seminar

## GE.CVS.404 - Designing and Conducting Clinical Trials in Rare Cardiac Disease

#### 120B

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Carolyn Ho, Boston, MA

5:30 PM

Moderator

Sharlene M Day, Ann Arbor, MI

5:30 PM

The Peril and Promise of Conducting Trials in Rare Genetic Heart Disease

Prince J Kannankeril, Nashville, TN

5:45 PM

The Regulator's Perspective on Study Design and Outcome Selection for Rare Cardiovascular Disease

Robert M Califf, Durham, NC

6:00 PM

How Do We Recruit Patients With Rare Diseases into Clinical Studies?

Wagle Nikhil, Boston, MA

6:15 PM

Selecting Outcomes in Trials for Rare Heart Disease; Which Are Valid and Which Are Feasible?

Lynn A Sleeper, Waltham, MA

6:30 PM

Panel Discussion

# Cardiovascular Seminar

## EA.CVS.71 - New Insights into Arrhythmias and Cognitive Function

#### 113BC

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Lin Chen, Minneapolis, MN

5:30 PM

Catheter Ablation and Brain Injury: Implications for Dementia Prevention

T. Jared Bunch, Murray, UT

5:42 PM

Q&A

5:45 PM

Oral Anticoagulation and Prevention of Dementia in AF

Leif Friberg, Stockholm, Sweden

5:57 PM

Q&A

6:00 PM

AF and Dementia: Potential Mechanisms and Implications for Prevention

T. Jared Bunch, Murray, UT

6:12 PM

Q&A

6:15 PM

Is AF a Risk Factor for Alzheimer's Disease?

Nikolaos Dagres, Athens, Greece

6:27 PM

Q&A

6:30 PM

AF and Brain Morphological Changes: Insights Into AF-Related Dementia

Alvaro Alonso, Atlanta, GA

6:42 PM

Q&A

# Cardiovascular Seminar

## IN.CVS.409 - Next Frontiers in Transcatheter Structural Heart Therapies

#### 107AB

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

David Paniagua, Houston, TX

5:42 PM

Panel Discussion

5:48 PM

Invited Presenter - Novel Transcatheter Therapies for Valvular Heart Disease

Michael H Salinger, Milwaukee, WI

6:00 PM

Panel Discussion

6:06 PM

Invited Presenter - Tricuspid Valve Edge-to-edge Repair

Christian Besler, Leipzig, Germany

6:18 PM

Panel Discussion

6:24 PM

Invited Presenter: Transcatheter Pulmonic Valve Therapies

Jacqueline Kreutzer, Pittsburgh, PA

6:36 PM

Panel Discussion

5:30 PM

Panel Participant

Igor F Palacios, Boston, MA

# Cardiovascular Seminar

## CH.CVS.486 - The Team Approach to Congenital Heart Disease: Interventional and Surgical Collaboration

#### 111AB

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Bryan H Goldstein, Cincinnati, OH

5:30 PM

Moderator

Jennifer Romano, Ann Arbor, MI

5:30 PM

Perventricular Closure of VSDs

Brent M Gordon, Loma Linda, CA

5:45 PM

The Stage I Hybrid- Where Are We Now?

Aimee K Armstrong, Columbus, OH

6:00 PM

Intraoperative Pulmonary Artery Angiography and Stenting

Jeffrey Zampi, Ann Arbor, MI

6:15 PM

Hybrid Approach to Transcatheter Atrioventricular Valves in Small Patients

Diego Porras, Brookline, MA

6:30 PM

Cardiac Resynchronization Therapy in Pediatric Heart Failure

Francis Fynn-Thompson, Boston, MA

# Cardiovascular Seminar

## NR.CVS.118 - ZNA vs. DNA: How Important Is Zip Code In Care Planning?

#### 118C

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Connie White-Williams, Birmingham, AL

5:30 PM

Moderator

Deborah L Crabbe, Philadelphia, PA

5:30 PM

Introduction

5:35 PM

Are SODH a New Vital Sign for Evaluating Individuals and Communities?

Laura P Rossi, Boston, MA

5:55 PM

Innovative Models to Improve Access to Care and Community Networks

Bradi B Granger, Durham, NC

6:35 PM

Discussion

# Early Career

## CH.EC.317 - Chutes and Ladders: Navigating and Empowering Early Career Faculty and Fellows

#### Heart Theater

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Elizabeth Blume, Boston, MA

5:30 PM

Moderator

Nelangi Pinto, tbd, KS

5:30 PM

Stranded by Communication

Nelangi Pinto, Salt Lake Cty, UT

5:30 PM

Career Development - Fellow Vignette

Kae Watanabe, Chicago, IL

5:35 PM

Mentors and Mentees

Sara Pasquali, Ann Arbor, MI

5:50 PM

The Complex Learner

Britton C Keeshan, Lake Forest Park, WA

5:57 PM

Teaching the Resident that doesn't want to be Taught

Antonio Cabrera

6:15 PM

Preventing Burnout and Promoting Wellness

Liz Crowe, Australia

# Early Career

## NR.EC.312 - Negotiating Your Career

#### 120A

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Bunny J Pozehl, Omaha, NE

5:30 PM

Moderator

Kenneth M FAULKNER, Rocky Point, NY

5:30 PM

Student Panelist

Yamnia Cortes, Chapel Hill, NC

5:40 PM

Post-doc Panelist

Billy Caceres, Forest Hills, NY

5:50 PM

Early Career Panelist

Ruth Masterson-Creber, New York, NY

6:00 PM

Newly Tenured Panelist

Lisa Bratzke, Madison, WI

6:10 PM

Tenured Panelist

Susan Pressler, Indianapolis, IN

6:30 PM

Discussion

# Hybrid

## AT.HB.470 - Metabolic and Inflammatory Regulation of Atherosclerosis and Aneurysm

#### 126A

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Guo-ping Shi, Boston, MA

5:30 PM

Moderator

Meixiang Xiang, Hangzhou, China

5:30 PM

Adipocytes promote IL18 binding to its receptors during abdominal aortic aneurysm formation

Guo-ping Shi, Boston, MA

5:40 PM

Q&A

5:45 PM

Regulation of aortic aneurysm in diabetes

richard Bulbulia, Oxford, United Kingdom

5:55 PM

Q&A

6:00 PM

Lyve-1 Negative Bone Marrow-Derived Macrophages Drive Aortic Aneurysm/Dissection

Angela Li, Rickvinder Besla, Emily Chen, Shaun Pacheco, Takuo Emoto, Marwan Althagafi, Toronto General Res Inst, Toronto, ON, Canada; Myron I Cybulsky, Toronto General Hosp, Toronto, ON, Canada; Clint S. Robbins, Univ Health Network, Toronto, ON, Canada; **John S Byrne** , Toronto General Hosp, Toronto, ON, Canada

6:10 PM

Q & A

6:15 PM

Endothelial Microrna-335 Promotes a Vascular and Metabolic Inflammatory Milieu

**Takaomi Adachi** , Yale Univ Sch of Med, New Haven, CT

6:25 PM

Q & A

6:30 PM

Neutrophil Extracellular Traps (NETs) Promote Macrophage Inflammation and Contribute to Diabetes-Impaired Atherosclerosis Regression

**Tatjana Josefs** , Tessa Barrett, Emily Brown, Alexandra Quezada, Yoscar Ogando, Felix Zhou, NYU Sch of Med, New York, NY; Edward A Fisher, NYU Langone Medical Ctr, New York, NY

6:40 PM

Q & A

# Hybrid

## AT.HB.466 - Novel Insights into Coronary Arterial Disease and Aging

#### 126B

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Xiao-Li Tian, Nanchang

5:40 PM

Q&A

5:55 PM

Q&A

6:00 PM

Aging Enhances Vascular Mitochondrial Dysfunction Prior to Hyperlipidemia to Accelerate Atherosclerosis

**Daniel Tyrrell** , Daniel R Goldstein, Univ of Michigan, Ann Arbor, MI

6:10 PM

Q&A

6:15 PM

Inactivation of Lysyl Oxidase in Smooth Muscle Cells Reduces Atherosclerotic Burden in Hyperlipidemic Mice

Diana Hernandez, Univ of Miami, Miami, FL; Miguel Rojas, Univ of Miami, Miami Beach, FL; Gioser Ramos, Laisel Martinez, Nieves Santos, Zachary Zigmond, Univ of Miami, Miami, FL; Omaida Caridad Velazquez, Univ of Miami Miller Sch of Med, Miami, FL; **Roberto I Vazquez Padron** , Univ of Miami, Miami, FL

6:25 PM

Q&A

6:30 PM

Loss of Endothelial c-Myc Triggers Visceral Fat Accumulation in Aging Mice Associated With Serum Increase in Cholesterol and Leptin

**Jacqueline Freire Machi** , Yue Qi, Alejo Morales, Diego Henrique Silvestre, Isabella Altilio, Joao Pedro Werneck De Castro, Ernesto Bernal Mizrachi, Univ of Miami, Miami, FL; Claudia Rodrigues, Univ Miami Miller Sch Med, Miami, FL

6:40 PM

Q&A

# Joint Sessions

## CS.JS.626 - Road Maps for the Americas: Where We Are Going in the Control of Cardiovascular Diseases: Joint Session with AHA and InterAmerican Society of Cardiology

#### 121A

### Sunday, November 17, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Gustavo Restrepo Molina, Medellin, Colombia

5:30 PM

Road Maps for Diagnosis and Treatment of Hypertension in the Americas

Fernando Stuardo Wyss Sr., Guatemala, Guatemala

5:40 PM

Q&A

5:55 PM

Q&A

6:10 PM

Q&A

6:25 PM

Q&A

6:30 PM

Road Map for Zika Carditis: Management and Plans for 2019

Ivan Mendoza Sr., Caracas, Venezuela, Bolivarian Republic of

6:40 PM

Q&A

# Meet the Trialists

## CS.MT.05 - Meet the Trialists TWILIGHT-ACS

#### EP Central

### Sunday, November 17, 2019, 5:30 PM - 6:15 PM

5:30 PM

TWILIGHT-ACS

Usman Baber, New York, NY

# Unofficial Satellite Events

## USE.12 - "Denka Seiken sdLDL-C: New Study Results for 2019"

#### Marriott Philadelphia Downtown, Franklin Hall 8

### Sunday, November 17, 2019, 7:00 PM - 9:00 PM

7:00 PM

Programming

# Unofficial Satellite Events

## USE.11 - A Crucial Equation to Reduce Future CV Events: A Multi-Pronged Approach to LDL-C Lowering

#### Le Méridien Philadelphia, Trumbauer Ballroom

### Sunday, November 17, 2019, 7:00 PM - 8:30 PM

7:00 PM

Programming

# Unofficial Satellite Events

## USE.10 - Esperion's Corporate Introduction

#### The Logan Hotel

### Sunday, November 17, 2019, 7:00 PM - 8:00 PM

7:00 PM

Programming

# Unofficial Satellite Events

## USE.13 - Hot Off the Press: Primary Prevention of MI in High-Risk Patients

#### Philadelphia Marriott Downtown, Salon E, 5th Floor

### Monday, November 18, 2019, 7:00 AM - 8:30 AM

7:00 AM

Programming

# Abstract Oral Session

## CA.AOS.549 - Epigenetics? That's How the Liberty Bell was Really Cracked!

#### 120A

### Monday, November 18, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Nicole H Purcell, La Jolla, CA

7:15 AM

Moderator

Federica Accornero, Dublin, OH

7:15 AM

Chromatin Remodelling by the Methyltransferase Setd7 Participates to Obesity-Related Heart Failure With Preserved Ejection Fraction

**Sarah Costantino** , Univ of Zurich, Schlieren, Switzerland; Giovanni Melina, Ospedale Sant'Andrea, Roma, Italy; Alexander Akhmedov, Zurich Univ, Schlieren, Switzerland; Samuele Ambrosini, Shafeeq A Mohammed, Univ of Zurich, Schlieren, Switzerland; Riccardo Sinatra, Sant'Andrea Hosp, "Sapienza" Univ, Rome, Italy; Thomas F Luescher, Univ of Zurich, Schlieren, Switzerland; Francesco Paneni, Univ of Zurich, Schlieren

7:25 AM

Q & A

7:30 AM

Myocardial Transcriptomics Reveal Distinct Gene Expression in Human Heart Failure With Preserved Ejection Fraction

**Virginia Shalkey Hahn** , Hildur Knutsdottir, Joel S Bader, Johns Hopkins Univ, Baltimore, MD; Kenneth C Bedi, Kenneth Margulies, Univ of Pennsylvania, Philadelphia, PA; Saptarsi Haldar, Amgen Res, South San Francisco, CA; Marina Stolina, Amgen Res, Thousand Oaks, CA; Jun Yin, Amgen Res, South San Francisco, CA; Aarif Khakoo, Calico Life Sciences, South San Francsico, CA; Kavita Sharma, Johns Hopkins Univ SOM, Baltimore, MD; David Alan Kass, Johns Hopkins Medical Inst, Baltimore, MD

7:40 AM

Q & A

7:45 AM

Cardiac Nitric Oxide Synthase 1 Worsens Diastolic Dysfunction Through S-nitrosylation of Histone Deacetylase 2

**Somy Yoon** , Mira Kim, Chonnam Natl Univ, Jeollanam-do, Korea, Republic of; Youngkeun Ahn, Chonnam Nat Univ Hosp, Gwangju, Kosovo, Republic of; Yong Sook Grace KIM, Biomedical Res Inst, Gwangju, Korea, Republic of; Hyun Kook, Chonnam Natl Univ Med Sch, Hwasun-gun Jeollanamdo, Korea, Republic of; Gwang Hyeon Eom, Chonnam Natl Univ Med Sch, Gwangju, Korea, Republic of

7:55 AM

Q & A

8:00 AM

Methylation, Mis-Splicing and Expression of Pathological Isoforms in a Disease Causing Csrp3/Mlp Mutation

**Zaher ElBeck** , Mohammad Bakhtiar Hossain, Dominique Koppenhöfer, Humam Siga, Xidan Li, Valerio Azzimato, Byambajav Buyandelger, ICMC, Karolinska Instt, Huddinge, Sweden; Karine N Enesa, Roy Milner, AstraZeneca, Cambridge, United Kingdom; John Wiseman, Mohammad Bohlooly-Y, AstraZeneca, Gothenburg, Sweden; Akos Vegvari, Karolinska Instt, Solna, Sweden; Ralph Knöll, ICMC, Karolinska Instt, Huddinge, Sweden

8:10 AM

Q & A

8:15 AM

Negative Elongation Factor A (Nelfa) Required for RNA Pol II -Dependent Gene Transcription During Cardiac Hypertrophy

Saleena Alikunju, Elena Severivona, RUTGERS- NJMS, Newark, NJ; Zhi Yang, Rutgers NJMS, Newark, NJ; **Danish H Sayed** , RUTGERS- NJMS, Newark, NJ

8:25 AM

Q & A

# Abstract Oral Session

## IN.AOS.488 - Innovations in Structural Heart Disease

#### 204C

### Monday, November 18, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Khaled M Ziada, Lexington, KY

7:25 AM

Q & A

7:30 AM

Timing of Aortic Valve Intervention in Patients With Severe Symptomatic Aortic Stenosis in The United States - Predictors of Delay and Relationship of Delay With Mortality

**Aakriti Gupta** , Maria C Alu, Martin B Leon, Columbia Univ Medical Ctr, New York, NY

7:40 AM

Q & A

7:45 AM

Clopidogrel Resistance in Patients Undergoing Left Atrial Appendage Closure With the Watchman Device

**Domenico Giovanni Della Rocca** , St. David's Medical Ctr, Austin, TX; Carola Gianni, Texas Cardiac Arrhythmia Inst, Austin, TX; Rodney Paul Horton, St David's Medical Ctr, Austin, TX; Luigi Di Biase Sr., Albert Einstein Coll of Med, New York, NY; Sanghamitra Mohanty, Texas Cardiac Arrhythmia Inst, Austin, TX; Chintan Gautambhai Trivedi, St David's Medical Ctr, Austin, TX; Veronica Natale, St David's Medical Ctr, Austin; Bryan MacDonald, St Daivd's Medical Ctr, Austin, TX; Jorge Romero, Montefiore Albert Einstein, Bronx, NY; Mohamed Ahmed Bassiouny, Cleveland Clinic Fndn, Cleveland, OH; Amin Al-Ahmad, St. David's Medical Ctr, Austin, TX; David Burkhardt, St David's Medical Ctr, Austin; G Joseph Gallinghouse, St. David's Medical Ctr, Austin, TX; Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

7:55 AM

Q & A

8:00 AM

Blood Coagulation Status After Transcatheter Aortic Valve Implantation in Patients With/Without Oral Anticoagulant Therapy

**Taiga Katayama** , Naoyuki Yokoyama, Yusuke Watanabe, Shinji Takahashi, Hirofumi Hioki, Hirosada Yamamoto, Teikyo Univ Sch of Med, Tokyo, Japan; Kazuo Kawasugi, Teikyo Univ, Tokyo, Japan; Ken Kozuma, Teikyo Univ Sch of Med, Tokyo, Japan

8:10 AM

Q & A

8:15 AM

Mechanical Stress on the Leaflets of an Aortic Self-Expanding Transcatheter Prosthesis After Valve-in-Valve Implantation: An in vitro Study

**Anne-Sophie Zenses** , IUCPQ, Univ Laval, Quebec, QC, Canada; Viktoria Stanova, Hugo A M Oliveira, IFSTTAR, Aix-Marseille Univ, Marseille, France; Jean-François Obadia, Hop Cardiothoracique, Lyon, France; Lyes Kadem, Lab of Cardiovascular Fluid Dynamics, Concordia Univ, Montreal, QC, Canada; Regis Rieu, IFSTTAR, Aix-Marseille Univ, Marseille, France; Philippe Pibarot, IUCPQ, Univ Laval, Quebec, QC, Canada

8:25 AM

Q & A

# Abstract Oral Session

## CH.AOS.500 - Pediatric/Congenital Oral Abstracts - Top Clinical Science

#### 112AB

### Monday, November 18, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Meryl S Cohen, Philadelphia, PA

7:15 AM

Moderator

Jennifer Romano, Ann Arbor, MI

7:15 AM

National Variation in Congenital Heart Surgery Outcomes and Impact on Strategies For Improvement

**Sara K Pasquali** , Univ of Michigan, Ann Arbor, MI; Dylan Thibault, Duke Univ, Durham, NC; Jeffrey P Jacobs, Johns Hopkins All Children's Hospit, Saint Petersburg, FL; J. William Gaynor, Children's Hosp of Philadelphia, Philadelphia, PA; Jennifer C. Romano, Univ of Michigan Hosp, Ann Arbor, MI; Michael G Gaies, Univ of Michigan, Ann Arbor, MI; Sean M O'Brien, Kevin D Hill, Duke Univ, Durham, NC; Marshall L. Jacobs, Johns Hopkins Sch of Med, Baltimore, MD; David M Shahian, Massachusetts General Hosp, Sudbury, MA; John E Mayer, Boston Children's Hosp, Boston, MA

7:25 AM

Q & A

7:30 AM

Cardiac Arrest Prevention Quality Improvement Project From the Pediatric Cardiac Critical Care Consortium

**Jeffrey Alten** , Cincinnati Childrens Hosp Medical Ctr, Cincinnati, OH; Darren Klugman, Childrens Natl Health System, Chevy Chase, MD; David S Cooper, Cincinnati Childrens Hosp Medical Ctr, Cincinnati, OH; Tia Tortoriello Raymond, Medical City Childrens Hosp, Dallas, TX; Sharyl Wooton, Cincinnati Children's Hosp, Sylva, NC; Katherine Clarke-Myers, Cincinnati Children's Hosp, Cincinnati, OH; Jeffrey B Anderson, Mousumi Banerjee, Cincinnati Childrens Hosp Medical Ctr, Cincinnati, OH; Sara K Pasquali, Michael G Gaies, Univ of Michigan, Ann Arbor, MI; on behalf of PC4 CAP Investigators

7:40 AM

Q & A

7:45 AM

**Successful Reduction of Postoperative Chest Tube Duration and Length of Stay After Congenital Heart Surgery: A Multicenter Pediatric Acute Care Cardiology Collaborative (pac** 3 **) and Pediatric Cardiac Critical Care Consortium (pc** 4 **) Improvement Project**

**Katherine E Bates** , Univ of Michigan, Ann Arbor, MI; Nicolas L Madsen, Cincinnati Childrens Hosp, Cincinnati, OH; Lara Khadr, Univ of Michigan, Ann Arbor, MI; Margaret Graupe, Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; Anthony M Hlavacek, Medical Univ of South Carolina, Charleston, SC; Evonne Morell, Univ of Pittsburgh Medical Ctr Children's Hosp of Pittsburgh, Pittsburgh, PA; Sara K Pasquali, Univ of Michigan, Ann Arbor, MI; Jennifer L Russell, The Hosp for Sick Children, Toronto, ON, Canada; Susan K Schachtner, Chidrens Hosp Philadelphia, Philadelphia, PA; Ronn E Tanel, UC San Francisco, San Francisco, CA; Adam L Ware, Univ of Utah, Salt Lake City, UT; Sharyl Wooton, Cincinnati Children's Hosp and Medical Ctr, Cincinnati, OH; Alaina K Kipps, Stanford Children's Health, Palo Alto, CA

7:55 AM

Q & A

8:00 AM

Comparison of Management Strategies for the Neonate With Symptomatic Tetralogy of Fallot: A Study From the Congenital Catheterization Research Collaborative

**Bryan H Goldstein** , Cincinnati Children's Hosp, Cincinnati, OH; Christopher J Petit, Emory Univ Sch of Med, Atlanta, GA; Athar M Qureshi, Texas Children's Hosp, Houston, TX; Courtney E McCracken, Michael S Kelleman, Emory Univ Sch of Med, Atlanta, GA; George T Nicholson, Monroe Carell Jr. Children's Hosp at Vanderbilt, Nashville, TN; Mark A Law, Univ of Alabama Birmingham, Vestavia, AL; Jeffery J Meadows, UCSF, San Francisco, CA; Jeffrey D Zampi, Univ of Michigan, Ann Arbor, MI; Shabana Shahanavaz, Washington Univ in St. Louis, Saint Louis, MO; Christopher E Mascio, Children's Hosp of Philadelphia, Philadelphia, PA; Paul J Chai, Children's Healthcare of Atlanta, Atlanta, GA; Jennifer C Romano, Univ of Michigan, Ann Arbor, MI; Ivor B Asztalos, Children's Hosp of Philadelphia, Philadelphia, PA; Lindsay F Eilers, Texas Children's Hosp, Houston, TX; Alicia M Kamsheh, Children's Hosp of Philadelphia, Philadelphia, PA; Steven J Healan, Vanderbilt Children's Hosp, Nashville, TN; Justin Smith, Univ of Michigan, Ann Arbor, MI; R. Allen Ligon, Sarina Juma, Children's Healthcare of Atlanta, Atlanta, GA; James Eb Raulston, Univ of Alabama Birmingham, Birmingham, AL; Sarosh P Batlivala, Cincinnati Children's Hosp, Cincinnati, OH; Hala Q Khan, Texas Children's Hosp, Houston, TX; Taylor C Merritt, Matthew Candor, St. Louis Children's Hosp, St. Louis, MO; Stephan Juergensen, Fatuma A Rinderknecht, Univ of California San Francisco, San Francisco, CA; Amy L Pajk, Cincinnati Children's Hosp, Cincinnati, OH; Joelle A Pettus, Holly Bauser Heaton, Children's Healthcare of Atlanta, Atlanta, GA; Andrew C Glatz, Children's Hosp of Philadelphia, Swarthmore, PA

8:10 AM

Q & A

8:15 AM

Impact of Intraoperative Methylprednisolone on Neurodevelopmental Outcomes in Neonates Undergoing Cardiac Surgery

**Sinai C Zyblewski** , Renee H Martin, Virginia B Shipes, Kasey Hamlin-Smith, Medical Univ of South Carolina, Charleston, SC; Andrew M Atz, Medical Univ of South Carolina, Mt Pleasant, SC; Scott M Bradley, Minoo N Kavarana, Medical Univ of South Carolina, Charleston, SC; William T Mahle, Emory, Atlanta, GA; Allen D Everett, Johns Hopkins, Glenwood, MD; Eric M Graham, Medical Univ of South Carolina, Charleston, SC

8:25 AM

Q & A

# Cardiovascular Seminar

## CA.CVS.115 - Calcium Release Refractoriness and Calcium Alternans: Emerging Views

#### 119AB

### Monday, November 18, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Bjorn C KNOLLMANN, Nashville, TN

7:15 AM

Moderator

Alicia Mattiazzi, La Plata, Argentina

7:15 AM

Store Overload Calcium Release and the Luminal Calcium Threshold Concept Revisited

Sandor Gyorke, Columbus, OH

7:28 AM

Q & A

7:30 AM

Does the Velocity of SR Ca Refilling Influence Ca Release Refractoriness? An Experimental and Computational Study

Juan I Felice, La Plata, Argentina

7:43 AM

Q & A

7:45 AM

Importance of Calcium Release vs. Calcium Uptake in Calcium Refractoriness and Calcium Alternans Determinations

Leif Hove-Madsen, Barcelona

7:58 AM

Q & A

8:00 AM

Mechanisms of Calcium Alternans. Insights From a Human Myocyte Model

Blanca Rodriguez, Oxford, United Kingdom

8:13 AM

Q & A

8:15 AM

Action Potential Alternans and Calcium Alternans. Which Come First?

Lothar Blatter, Chicago

8:28 AM

Q & A

# Cardiovascular Seminar

## PH.CVS.589 - Developmental Origins of Pulmonary Vascular Disease: Bridging Pediatric and Adult PAH

#### 102AB

### Monday, November 18, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Kara Goss, Madison, WI

7:15 AM

Moderator

Michael L O'Byrne, Philadelphia, PA

7:15 AM

Bronchopulmonary Dysplasia, Prematurity and Risk for Chronic Lung Disease in Premature Infants

John Berger, Washington, DC

7:25 AM

Discussion

7:30 AM

Syndromic Pulmonary Arterial Hypertension

Jeffrey R Fineman, San Francisco, CA

7:40 AM

Discussion

7:45 AM

Elevated Risk of PAH, RV Dysfunction, and Heart Failure in Adult Survivors of Preterm Birth

Kara Goss, Madison, WI

7:55 AM

Discussion

8:00 AM

Role of Intrauterine Stress in Modifying Pulmonary Vascular Development

Steven Herbert Abman, Denver, CO

8:10 AM

Discussion

8:15 AM

Congenital Diphgragmatic Hernia and PAH

Rachel K Hopper, Palo Alto, CA

8:25 AM

Discussion

# Cardiovascular Seminar

## AT.CVS.236 - Endothelial Cell Metabolism

#### 126A

### Monday, November 18, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Zoltan Arany, Philadellphia

7:15 AM

Moderator

Hong Chen, Boston, MA

7:15 AM

The Link Between Angiogenesis and Endothelial Metabolism

Peter Carmeliet, Leuven, Belgium

7:25 AM

Q&A

7:30 AM

Whole-body Metabolic Fate of Branched-Chain Amino Acids

Zoltan Arany, Philadellphia

7:40 AM

Q&A

7:45 AM

Regulation of Mitochondria-Associated ER Membrane Remodeling Under Hyperglycemia in Endothelial Cell

Jun Yu, Philadellphia

7:55 AM

Q&A

8:00 AM

Endothelial FoxO in Angiogenesis in Hyperlipidemic Mouse

Tara L Haas, Torrento, Canada

8:10 AM

Q&A

8:15 AM

Hyperhomocysteinemia and Endothelial Dysfunction

Hong Wang, Philadellphia

8:25 AM

Q&A

# Cardiovascular Seminar

## PH.CVS.188 - Epigenetic and Noncoding RNA Regulation of Pulmonary Vascular Remodeling

#### 103A

### Monday, November 18, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

francois Potus, Kingston, ON, Canada

7:15 AM

Moderator

Katharine Clapham, New Haven, CT

7:15 AM

Moderator

Mark Ormiston, Kingston, ON, Canada

7:15 AM

Role of Non-Coding RNA in PAH

Sebastien Bonnet, Quebec City, QC, Canada

7:27 AM

Novel Mutations and Decreased Expression of Epigenetic Regulators TET2 and DNMT3A in Pulmonary Arterial Hypertension

Stephen Archer, Kingston, ON, Canada

7:39 AM

Epigenetics Offers New Therapeutic Targets

Kurt R Stenmark, Aurora, CO

7:51 AM

Histone Acetylation, Histone Methylation and Histone Readers: The Histone Code in Pulmonary Hypertension

Olivier Boucherat, Quebec, QC, Canada

8:03 AM

Pulmonary Vascular Remodelling and miRNA Pathway in PAH

Stephen Y. Chan, Pittsburgh, PA

8:15 AM

Panel Discussion

# Cardiovascular Seminar

## NR.CVS.77 - Make Yourself at Home: Bringing Hospital Care to the Home for Pediatric Heart Disease

#### 113A

### Monday, November 18, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Sandra Staveski, San Francisco, CA

7:15 AM

Moderator

Brian McCrindle, Toronto, ON, Canada

7:15 AM

Introduction

7:18 AM

Type of Device and Home Plan: VAD Monitoring,

Jenna Murray, Mountain View, CA

7:36 AM

Keeping Within Range: AntiCoagulation Monitoring

Mary Bauman, Edmonton, AB, Canada

7:54 AM

The iPhone's New Use: Pacemaker / AICD Monitoring

Yaniv Bar-Cohen, Los Angeles, CA

# Cardiovascular Seminar

## VA.CVS.500 - PVD Workshop: Venous Disease and Thrombosis

#### 103B

### Monday, November 18, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Scott M Damrauer, Philadelphia, PA

7:15 AM

Genomic and clinical predictors of varicose veins

Eri Fukaya, Stanford, CA

7:30 AM

Contemporary management of venous insufficiency

Julia D Glaser, Philadelphia, PA

7:45 AM

Genetics of venous thromboembolism, treatment opportunities, and risk prediction

Pradeep Natarajan, Boston, MA

8:00 AM

Contemporary role for catheter directed lysis in the management of deep venous thrombosis

Nicole L Lohr, Milwaukee, WI

8:15 AM

Discussion

# Cardiovascular Seminar

## CE.CVS.455 - The Future of Cell-Based Therapies

#### 120C

### Monday, November 18, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Ivonne Hernandez Schulman, Miami, FL

7:15 AM

Moderator

Doris A Taylor, Houston, TX

7:15 AM

Cell-Based Therapy For Cardiomyopathies

Mary Kearns-Jonker, Santa Clarita, CA

7:25 AM

Q&A

7:30 AM

Cell-Based Therapy For Cardiomyopathies

Joshua M Hare, Miami, FL

7:40 AM

Q&A

7:45 AM

Cell-Based Therapy For Cardiomyopathies

Sadia Mohsin, Philadelphia, PA

7:55 AM

Q&A

8:00 AM

Clinical Trials of Pluripotent Stem Cell-Based Cardiac Therapies

Philippe Menasche, Paris, France

8:10 AM

Q&A

8:15 AM

Generation of Ventricular Cardiomyocytes for Pluripotent Stem Cell-Based Cardiac Cell Therapeutics

Stephanie Protze, Toronto, ON, Canada

8:25 AM

Q&A

# Cardiovascular Seminar

## CE.CVS.100 - Young at Heart: Mechanisms Underlying Cardiac Aging

#### 120B

### Monday, November 18, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Jennifer Kwong, Atlanta, GA

7:15 AM

Moderator

Lorrie Kirshenbaum, MB, Canada

7:15 AM

MAGIC and Mitochondrial Aging

Rong Li, Baltimore, MD

7:28 AM

Q&A

7:33 AM

Alzheimer's Disease and Cardiac Aging

Federica del Monte, Charleston, SC

7:46 AM

Q&A

7:51 AM

Cardiac Macrophage Biology in the Aging Heart

Merry L Lindsey, Jackson, MS

8:04 AM

Q&A

8:09 AM

Visceral Adipose Tissue Drives Cardiac Aging Through Modulation of Fibroblast Senescence

Genevieve Derumeaux, Créteil, France

8:22 AM

Q&A

# Frontiers in Science

## AT.FIS.339 - Frontiers in Thrombosis: Progress in Venous Thromboembolism

#### 126B

### Monday, November 18, 2019, 7:15 AM - 8:30 AM

7:15 AM

Moderator

Andrea T Obi, Ann Arbor, MI

7:15 AM

Moderator

Lana Castellucci, Ottawa, ON, Canada

7:15 AM

Animal Models of Venous Thrombosis

Jose A Diaz, Nashville, TN

7:25 AM

Q&A

7:40 AM

Q&A

7:45 AM

Perioperative Management of DOACs

James Douketis, Hamilton, ON, Canada

7:55 AM

Q&A

8:00 AM

Risks and Benefits of Long-Term Anticoagulation in VTE

Lana Castellucci, Ottawa, ON, Canada

8:10 AM

Q&A

8:15 AM

The Promise of New Anticoagulants Targeting Factors XI and XII

Pancras C Wong, Pennington, NJ

8:25 AM

Q&A

# Cardiovascular Seminar

## CO.CVS.619 - Novel Concepts in Cardio-Oncology

#### 204AB

### Monday, November 18, 2019, 7:30 AM - 8:45 AM

7:30 AM

Moderator

Tochi M OKWUOSA, Chicago, IL

7:30 AM

Moderator

Harsha Poola, Wauwatosa, WI

7:30 AM

Case Presenter

Kevin Michael Alexander, Mountain View, CA

7:35 AM

Multiple Myeloma - Cardiac Amyloidosis and Challenges of Management

Vlad G Zaha, Dallas, TX

7:45 AM

Q&A

7:55 AM

Case Presenter

Sherry-ann Brown, Rochester, MN

8:00 AM

Radiation-Induced Vascular Disease - When to Screen?

Anju Nohria, Boston, MA

8:10 AM

Q&A

8:20 AM

Case Presenter

Weijuan Li, Nashville, TN

8:25 AM

Peri-Stem Cell Transplantation - Current Concepts in Cardiac Evaluation

Jeanne M Decara, Chicago, IL

8:35 AM

Q&A

# Early Career

## IM.EC.325 - CVRI Imaging Bootcamp

#### 109AB

### Monday, November 18, 2019, 8:00 AM - 12:00 PM

8:00 AM

Moderator

Daniel Vargas, Denver, CO

8:00 AM

Moderator

Kooresh Shoghi, St Louis, MO

8:00 AM

Introduction

Daniel Vargas, Denver, CO

8:15 AM

Artificial Intelligence in Cardiovascular Imaging

Benoit Desjardins, Philadelphia

8:35 AM

FFR-CT in Clinical Practice

Harold Litt, Philadelphia, PA

8:55 AM

Cardiac CT Cases With ARS

Amar Shah, New York, NY

9:20 AM

Multiparametric Myocardial MR Mapping (T1, T2 and T2*) in Clinical Practice

Kate Hanneman, Toronto, ON, Canada

9:40 AM

Break

10:00 AM

Cardiac MR Cases with ARS

Daniel Vargas, Denver, CO

10:25 AM

Basic Adult Congenital Heart Disease Cases With MR

Madhukar Kollengode, Denver, CO

10:50 AM

What's New in Cardiac PET

Robert Beanlands, Ottawa, Canada

11:10 AM

Cardiac PET/SPECT Cases With ARS

David Wolinsky, Weston

11:35 AM

Discussion

# Abstract Oral Session

## AT.AOS.464 - George Lyman Duff Memorial Lecture

#### 126A

### Monday, November 18, 2019, 9:00 AM - 10:00 AM

9:00 AM

Moderator

Mary G Sorci Thomas, Milwaukee, WI

9:00 AM

Moderator

Yabing Chen, Birmingham, AL

9:00 AM

George Lyman Duff Memorial Lecture

Robert A Hegele, London, ON, Canada

9:25 AM

Q&A

9:30 AM

A Network Meta-Analysis on the Comparative Efficacy of Nutraceuticals on Lipid Profile

Jakub Morze, Univ of Warmia and Mazury, Olsztyn, Poland; Tadeusz Osadnik, Kamila Osadnik, Mateusz Lejawa, Grzegorz Jakubiak, Natalia Pawlas, Mariusz Gasior, Medical Univ of Silesia, Katowice, Poland; Lukas Schwingschackl, Medical Ctr Univ of Freiburg, Freiburg, Germany; **Maciej Banach** , Medical Univ of Lodz, Lodz, Poland

9:40 AM

Q & A

9:45 AM

Reduction of Insulin Like Growth Factor 1 Receptor in the Endothelium Causes an Altered Secretome Which Leads to Favourable Changes in White Adipose Tissue

Katherine Bridge, **Natalie Haywood** , Nele Warmke, Univ of Leeds, Leeds, United Kingdom; Romana Mughal, Univ of Leeds, Leeds; Amy Moran, Univ of Leeds, Leeds, United Kingdom; Nicole Watt, Univ of Leeds, Leeds; Andrew Walker, Univ of Leeds, Sheffield, United Kingdom; Nadira Yuldasheva, Lee Roberts, Anna Skromna, Natallia Makava, Stephen Wheatcroft, Univ of Leeds, Leeds, United Kingdom; Richard Cubbon, The Univ of Leeds, Leeds; Mark Kearney, Univ of Leeds, Leeds

9:55 AM

Q & A

# Abstract Oral Session

## CE.AOS.546 - Myofibroblast: The New "F" Word

#### 111AB

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Ronald J Vagnozzi, Cincinnati, OH

9:00 AM

IKKε Deficiency Aggravates Cardiac Fibrosis With Dysregulation of p52 in Myocardial Infarction

**Hyang Hee Cho** , Chonnam Natl Univ Graduate Sch, Gwangju, Korea, Republic of; Yong Sook Grace KIM, Dong Im Cho, Youngkeun Ahn, Chonnam Univ Hosp, Gwangju, Korea, Republic of

9:10 AM

Q & A

9:15 AM

Microrna-221 Attenuates the Development of Cardiac Fibrosis Caused by Renal Impairment via Inhibition of TSP-1 Mediated Latent TGF Activation

Yue Zhou, Natl Univ of Singapore, Singapore; Mark Richards, **Peipei Wang** , Natl Univ of Singapore, Singapore, Singapore

9:25 AM

Q & A

9:30 AM

EPRS Promotes Cardiac Fibrosis by Regulating Proline-Rich Pro-Fibrotic Protein Synthesis

Jiangbin Wu, Kadiam C Venkata Subbaiah, Feng Jiang, Omar Hedaya, Univ of Rochester Medical Ctr, Rochester, NY; Wai Hong Wilson Tang, Cleveland Clinic, Cleveland, OH; **Peng Yao** , Univ of Rochester Medical Ctr, Rochester, NY

9:40 AM

Q & A

9:45 AM

Galectin-3 Inhibition Reduces Cardiac Fibrosis and Prevents Progressive Heart Failure Following Myocardial Infarction

**Xiaoyin Wang** , UCSF, San Francisco, CA; Meenakshi Gaur, MandalMed, Inc., San Francisco, CA; Hilda Jessica Rodriguez, UCSF, San Francisco, CA; Khalil Mounzih, MandalMed, Inc., San Francisco, CA; Huiliang Qiu, Ming Chen, Liqiu Yan, Ronak Derakhshandeh, Shilpa Narayan, UCSF, San Francisco, CA; Brian Cooper, MandalMed, Inc., San Francisco, CA; Poonam Rao, Pooneh Nabavizadeh, Matthew L Springer, UCSF, San Francisco, CA; Constance M John, MandalMed, Inc., San Francisco, CA

9:55 AM

Q & A

10:00 AM

Thrombospondin-1 Null Mice Demonstrate Improved Right Ventricular Function but Not Decreased Fibrosis in Response to Right Ventricular Pressure-Loading

**Elizabeth Kim** , The Hosp for Sick Children Res Inst, Toronto, ON, Canada; Yohei Akazawa, The Hosp for Sick Children, Toronto, ON, Canada; Mei Sun, The Hosp for Sick Children Res Inst, Toronto, ON, Canada; Kabir Golam, Kim A Connelly, The Keenan Res Ctr for Biomedical Science, Toronto, ON, Canada; Mark Friedberg, The Hosp for Sick Children, Toronto, ON, Canada

10:10 AM

Q & A

# Abstract Oral Session

## NR.AOS.358 - Novel Approaches to Care Delivery for Cardiovascular Patients

#### 120B

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Nancy T Artinian, East Lansing, MI

9:00 AM

Moderator

Kim S Newlin, Granite Bay, CA

9:00 AM

Cost-effectiveness of an Inpatient Heart Failure Nurse Practitioner Service for Patients Admitted With Heart Failure

**Andrea Driscoll** , Deakin Univ, Geelong, Australia; Jennifer Watts, Deakin Univ, Burwood, Australia; Sharon Meagher, Rhoda Kennedy, Deakin Univ, Geelong, Australia; Ronald Mar, Austin Health, Heidelberg, Australia; Douglas Johnson, Royal Melbourne Hosp, Parkville, Australia; David L Hare, Univ Melbourne, Melbourne, Australia; Omar Farouque, Austin Health, Heidelberg, Australia; Louise M Burrell, Univ Melbourne, Heidleberg, Australia; Melodie Heland, Bernadette Twomey, Austin Health, Heidelberg, Australia; Lan Gao, Deakin Univ, Burwood, Australia

9:10 AM

Q & A

9:15 AM

A Behavioral Economics-based Telehealth Intervention to Improve Aspirin Adherence Following Hospitalization for Acute Coronary Syndrome

**Barbara Riegel** , Alisa Stephens-Shields, Anne Jaskowiak-Barr, Marguerite Daus, Univ Pennsylvania, Philadelphia, PA; Stephen Kimmel, Univ PA Sch Med, Philadelphia, PA

9:25 AM

Q & A

9:30 AM

Characterization of Patient Calls at Cardiac Device Clinics: Economic Implications and Opportunities for Improved Efficiency

**Laura Van Heel** , Centracare Heart & Vascular Ctr, Saint Cloud, MN; Amber Seiler, ConeHealth Medical Group HeartCare, Greensboro, NC; Theresa Cirocco, Julia Bayer, Henry Ford Health System, Detroit, MI; Laurence M Epstein, Northwell Health, North Shore Univ Hosptial, Manhasset, NY; Donna Kalenderian, Northwell Health, North Shore Univ Hosp, Manhasset, NY; Erin H Gillen, Hudson Valley Heart Ctr, Poughkeepsie, NY; Joel Ayala, Medtronic, Mounds View, MN

9:40 AM

Q & A

9:45 AM

Impact of a Nurse-Led Limited Risk Factor Modification Program on Arrhythmia Outcomes in Patients With Atrial Fibrillation Undergoing Catheter Ablation

**Amaryah Yaeger** , Brendan T. Keenan, Nancy R. Cash, Tara Parham, David S. Frankel, Rajat Deo, Robert D. Schaller, Pasquale Santangeli, Saman Nazarian, Gregory E. Supple, Jeffrey Arkles, Ramanan Kumareswaran, Matthew C. Hyman, Michael P. Riley, Fermin C. Garcia, David Lin, Andrew E. Epstein, David J. Callans, Francis E. Marchlinski, Jorge I. Mora, Anastassia Amaro, Richard Schwab, Allan Pack, Sanjay Dixit, Hosp of the Univ of Pennsylvania, Philadelphia, PA

9:55 AM

Q & A

10:00 AM

The Effects of a Single Session Education With Telephone Follow-Up on Mortality, Disease Knowledge, Self-Care, and Health-Related Quality of Life in Patients With Heart Failure

**Boyoung Hwang** , Seoul Natl Univ, Seoul, Korea, Republic of; Hyun-jai Cho, Hae-young Lee, Seoul Natl Univ Hosp, Seoul, Korea, Republic of

10:10 AM

Q & A

# Cardiovascular Seminar

## CH.CVS.506 - Adult Congenital Heart Disease for The General Cardiologist

#### 112AB

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Karen Stout, Seattle, WA

9:00 AM

Moderator

Michael J Landzberg, newton, MA

9:00 AM

Top Takeaways From the 2018 Management of ACHD Patients AHA/ACC Guidelines

Christopher Learn, Boston, MA

9:15 AM

Teaching Essentials of ACHD to Clinicians Who Don't Do it Everyday

Keri Shafer, Brookline, MA

9:30 AM

Establishing a New ACHD Program

Laith Alshawabkeh, La Jolla, CA

9:45 AM

Essentials for Caring for Pregnant Women With CHD

Candice Silversides, Toronto, ON, Canada

10:00 AM

Lessons I Wish I Had Learned in ACHD Fellowship to Help Me Care for ACHD Patients in My Home Country

Fernando Baraona, santiago

# Cardiovascular Seminar

## BC.CVS.100 - Bethesda + 41: 50x50x50 - Transforming the Cardiovascular Health of Youth for Generations to Come

#### Terrace Ballroom IV

### Monday, November 18, 2019, 9:00 AM - 12:15 PM

9:00 AM

Moderator

Stephen R Daniels, Aurora, CO

9:00 AM

Moderator

Gina S Wei, Bethesda, MD

9:00 AM

Bethesda Conferences and NHLBI's Vision

David C Goff Jr., Bethesda, MD

9:10 AM

50x50x50: The Concept

Darwin R Labarthe, Chicago, IL

9:20 AM

Current Trends in CVH Metrics in Children and Adolescents

Amanda Perak, Chicago, IL

9:30 AM

Intergenerational Transfer of CV Health and Risk: Epidemiological Perspective

Nisha I Parikh, San Francisco, CA

9:40 AM

CV Health and Risk: Molecular Perspective

Susan Ozanne, Cambridge, United Kingdom

9:50 AM

Break

9:55 AM

Evidence Base for CVH Interventions in Mothers

Charlotte A Pratt, Bethesda, MD

10:15 AM

Evidence Base for CVH Interventions in Adolescents and Young Adults

Holly Nicastro, Bethesda, MD

10:25 AM

Practice-Based Approaches to Improving CVH in Children

Sarah D De Ferranti, Boston, MA

10:45 AM

Break

11:00 AM

Roundtable Discussions

11:45 AM

Report Out

# Cardiovascular Seminar

## CO.CVS.620 - Cardio-Oncology Debates

#### 204AB

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Charles B Porter, Kansas City, KS

9:00 AM

Moderator

Theresa M Beckie, Tampa, FL

9:00 AM

Type I and II Cardiac Toxicity: It is complete Nonsense!

Michael George Fradley, Tampa, FL

9:09 AM

Type I and II Cardiotoxicity Makes Absolute Sense!

Jose Banchs, Houston, TX

9:17 AM

Rebuttal: Type I and II Cardiac Toxicity: It is complete Nonsense!

Michael George Fradley, Tampa, FL

9:21 AM

Rebuttal: Type I and II Cardiotoxicity Makes Absolute Sense!

Jose Banchs, Houston, TX

9:24 AM

Vote

9:26 AM

Myocarditis Associated with Immune Checkpoint Inhibitors: Cardiac Enzymes are Necessary in All Patients

Salim Hayek, Ann Arbor, MI

9:35 AM

Myocarditis Associated with Immune Checkpoint Inhibitors: Cardiac Enzymes are Necessary in Select Patients

Dipti Gupta, New York, NY

9:44 AM

Rebuttal: Myocarditis Associated with Immune Checkpoint Inhibitors: Cardiac Enzymes are Necessary in All Patients

Salim Hayek, Ann Arbor, MI

9:47 AM

Rebuttal: Myocarditis Associated with Immune Checkpoint Inhibitors: Cardiac Enzymes are Necessary in Select Patients

Dipti Gupta, New York, NY

9:49 AM

Vote

9:51 AM

Ibrutinib-Induced Atrial Fibrillation Should be Anticoagulated

Nausheen Akhter, Chicago, IL

9:59 AM

Ibrutinib-Induced Atrial Fibrillation Should not be Anticoagulated

Farrukh Awan, Dallas, TX

10:07 AM

Rebuttal: Ibrutinib-Induced Atrial Fibrillation Should be Anticoagulated

Nausheen Akhter, Chicago, IL

10:11 AM

Rebuttal: Ibrutinib-Induced Atrial Fibrillation Should not be Anticoagulated

Farrukh Awan, Dallas, TX

10:14 AM

Vote

# Cardiovascular Seminar

## CS.CVS.101 - Circulation and Circulation Research: Pulling Back the Scientific Publishing Curtain

#### 204C

### Monday, November 18, 2019, 9:00 AM - 10:30 AM

9:00 AM

Moderator

Joseph A Hill, Dallas, TX

9:00 AM

Moderator

Jane E Freedman, Worcester, MA

9:00 AM

Introduction: Overview & Who are all those people on the masthead?

Joseph A Hill, Dallas, TX

9:05 AM

Submitting to the Journal: The Authors' Role

Jane E Freedman, Worcester, MA

9:10 AM

Q&A: Submitting to the Journal: The Authors' Role

Joseph A Hill, Dallas, TX

9:15 AM

Editorial & Peer Review at the AHA Journals: What happens to your paper (and why)

Jane E Freedman, Worcester, MA

9:25 AM

Q&A - Editorial & Peer Review at the AHA Journals: What happens to your paper (and why)

Joseph A Hill, Dallas, TX

9:30 AM

The Reviewers Role

Jane E Freedman, Worcester, MA

9:35 AM

Almost Home: Revisions

Jane E Freedman, Worcester, MA

9:40 AM

Behind the scenes: Role of the Managing Editors and AHA

Jonathan Schultz, Baltimore, MD

9:45 AM

Post-Acceptance: Making your work known

9:45 AM

Panel - Post-Acceptance: Making your work known

Cynthia St Hilaire, Pittsburgh, PA

9:45 AM

Panel - Post-Acceptance: Making your work known

Milka Koupenova, Worcester, MA

9:55 AM

The Importance of Early Career Investigators to the Journals

Joseph A Hill, Dallas, TX

10:00 AM

**Case Studies in** Circulation **and** Circulation Research

# Cardiovascular Seminar

## NR.CVS.131 - Cognition Across the Lifespan: The Heart-Brain Connection

#### 113A

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Debra K Moser, Lexington, KY

9:00 AM

Moderator

Beverly Carlson, San Diego, CA

9:00 AM

Introduction

9:05:40 AM

Cognition - Overview and Importance

Lisa Bratzke, Madison

9:12:20 AM

Cognition in Congenital Heart Disease

Karen Uzark, Ann Arbor

9:25:40 AM

Cognition in Stroke

Trudy Gaillard, Miami

9:39 AM

Overview of Mechanisms: Cognitive Impair

Christopher S Lee, Boston, MA

9:45:40 AM

Assessing Cognitive Impairment in HF

Barbara Birriel, Hershey, PA

9:52:20 AM

Cognitive Impairment is a Family Affair

Lisa Kitko, University Park, PA

9:59 AM

Where Do We Go From Here?

Judith Hupcey, Hershey, PA

10:05:40 AM

Discussion

# Cardiovascular Seminar

## CH.CVS.608 - Congenital Heart Disease & Pediatric Cardiology Seminar: A Personalized Approach to Heart Disease in Children

#### 201AB

### Monday, November 18, 2019, 9:00 AM - 12:00 PM

9:00 AM

Moderator

Robert LEVY, Merion Sta, PA

9:00 AM

Moderator

Harold Baldwin, Nashville, TN

9:00 AM

What Causes Congenital Heart Disease? Developmental Biology of the Prenatal Heart

Deepak Srivastava, San Francisco, CA

9:15 AM

Clinical Translator/Commentator: What Causes Congenital Heart Disease? Developmental Biology of the Prenatal Heart

Patrick Jay, Saint Louis, MO

9:25 AM

Regenerative Cell Therapy in Congenital Heart Disease - Protecting the Immature Heart

Muhammad QURESHI, Rochester, MN

9:40 AM

Clinical Translator/Commentator: Regenerative Cell Therapy in Congenital Heart Disease - Protecting the Immature Heart

Richard Ohye, Ann Arbor, MI

9:50 AM

Regenerative Cell Therapy in Congenital Heart Disease - Protecting the Immature Brain

Richard Jonas, Washington, DC

10:05 AM

Clinical Translator/Commentator: Regenerative Cell Therapy in Congenital Heart Disease - Protecting the Immature Brain

Jane Newburger, Boston, MA

10:15 AM

Break

10:30 AM

Gene-based therapy for cardiomyopathies and muscular dystrophies: Where are we now?

Barry Byrne, Gainesville, FL

10:45 AM

Clinical Translator/Commentator: Gene-based therapy for cardiomyopathies and muscular dystrophies: Where are we now?

David Rosenthal, Palo Alto, CA

10:55 AM

Personalized Medicine in Diagnosis & Treatment of Inherited Arrhythmia Conditions

Susan Etheridge, Salt Lake Cty, UT

11:10 AM

Clinical Translator/Commentator: Personalized Medicine in Diagnosis & Treatment of Inherited Arrhythmia Conditions

Mitchell Cohen, Falls Church, VA

11:20 AM

Can real-time big data and predictive analytics improve Cardiac Intensive Care Unit outcomes?

Mjaye Mazwi, Toronto, ON, Canada

11:35 AM

Clinical Translator/Commentator: Can real-time big data and predictive analytics improve Cardiac Intensive Care Unit outcomes?

Gil Wernovsky, Philadelphia, PA

11:45 AM

Discussion

# Cardiovascular Seminar

## PH.CVS.545 - Gender Differences in Right Ventricular Function: From the Bench to the Bedside

#### 102AB

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Thenappan Thenappan, Minneapolis, MN

9:00 AM

Moderator

Stephen Archer, Kingston, ON, Canada

9:00 AM

Gender Differences in RV Function: Insights From the MESA-RV Study

Corey Ventetuolo, Providence, RI

9:15 AM

Effects of Estrogen on RV Adaptation in PH

TIM Lahm, Indianapolis, IN

9:30 AM

Gender Differences in RV-PA Coupling in Idiopathic Pulmonary Arterial Hypertension

Frances de Man, Amsterdam, Netherlands

9:45 AM

Male Gender is Associated With RV Dysfunction in Group 3 PH

Thenappan Thenappan, Minneapolis, MN

10:00 AM

Effects of Estrogen on Mitochondrial Functional in the RV in Rodent Pulmonary Hypertension

Naomi C Chesler, Madison, WI

# Cardiovascular Seminar

## IN.CVS.574 - Interventional Cases: Show and Tell from the Cath Lab

#### Heart Theater

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Subhash Banerjee, Dallas, TX

9:00 AM

Moderator

Mauricio G Cohen, Miami, FL

9:00 AM

Panel Participant

Subhash Banerjee, Dallas, TX

9:00 AM

Panel Participant

Prakash Balan, Houston, TX

9:00 AM

Introduction

9:05 AM

Challenging Coronary Cases

Emmanouil S Brilakis, Minneapolis, MN

9:20 AM

Discussion

9:30 AM

Challenging Peripheral Cases

Mehdi H Shishehbor, Cleveland, OH

9:45 AM

Discussion

9:55 AM

Challenging Structural Cases

Mauricio G Cohen, Miami, FL

10:10 AM

Discussion

# Cardiovascular Seminar

## GE.CVS.337 - New Uses of Genetics for Risk Prediction and Therapies

#### 121C

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Konstantinos Stellos, Newcastle Upon Tyne

9:00 AM

Moderator

Sharlene M Day, Ann Arbor, MI

9:00 AM

Polygenic Scores for Cardiovascular Risk Prediction

Sekar Kathiresan, Cambridge, MA

9:30 AM

Gene Editing as a Therapeutic Approach for Cardiovascular Disease

Alexandra C Chadwick, Boston, MA

9:45 AM

Gene Editing of iPSCs to Characterize Variants of Uncertain Significance in Cardiovascular Disease Genes

Kiran Musunuru, Philadelphia, PA

10:00 AM

Panel Discussion

# Cardiovascular Seminar

## MP.CVS.385 - Power Play: New Insights into Mitochondria

#### 120C

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Joan M Taylor, Chapel Hill, NC

9:00 AM

Moderator

Jason Karch, Houston, TX

9:00 AM

ANT as Novel Regulator of Mitophagy

Zoltan Arany, Philadelphia, PA

9:10 AM

Q&A

9:15 AM

Novel Pathways in Mitochondrial Quality Control

Asa B Gustafsson, La Jolla, CA

9:25 AM

Q&A

9:30 AM

EMRE and Calcium in Mitochondrial Homeostasis

Julia Liu, Bethesda, MD

9:40 AM

Q&A

9:45 AM

Metabolic Remodeling and Epigenetic Control

John W Elrod, Philadelphia, PA

9:55 AM

Q&A

10:00 AM

Mitochondrial Permeability Transition Pore in Heart

Elizabeth Murphy, Bethesda, MD

10:10 AM

Q&A

# Cardiovascular Seminar

## VA.CVS.501 - PVD Workshop: Aneurysm Disease

#### 103B

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Scott J Cameron, Solon, United States Minor Outlying Islands

9:00 AM

Clinical Update: Aortic root Aneurysmal disease in men and women - should we screen and treat differently?

Christina L Fanola, Boston, MA

9:20 AM

The role of aortic thrombus in the etiology of AAA: protective or detrimental?

A. Phillip Owens, Cincinnati, OH

9:40 AM

Aortic Disease Presentation: clinical and biomechanical aspects of AAA development in men and women

Doran S Mix, Henrietta, NY

10:00 AM

Discussion

# Cardiovascular Seminar

## CE.CVS.231 - Recent Advances in Hypertrophic Cardiomyopathy: Pathways to Treatments

#### 119AB

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Mathias Gautel, London, United Kingdom

9:00 AM

Moderator

Sakthivel Sadayappan, Cincinnati, OH

9:00 AM

Genetic Etiology of Hypertrophic Cardiomyopathy

Dhandapany Perundurai, Portland, OR

9:10 AM

Q&A

9:15 AM

Drug Discovery Approaches for Hypertrophic Cardiomyopathy

Christopher Semsarian, Sydney, Australia

9:25 AM

Q&A

9:30 AM

Molecular Strategies to Alleviate Hypertrophic Cardiomyopathy

Danuta Szczesna-Cordary, Miami, FL

9:40 AM

Q&A

9:45 AM

Small Molecules Targeting Myosin to Treat Hypertrophic Cardiomyopathy

Samantha P. Harris, Tucson, AZ

9:55 AM

Q&A

10:00 AM

Myofilaments in Hypertrophic Cardiomyopathy

Jil C Tardiff, TUCSON, AZ

10:10 AM

Q&A

# Cardiovascular Seminar

## HY.CVS.455 - Target: BP in Action - A Path to Better Blood Pressure Control

#### 108A

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Brent M Egan, Greenvile, SC

9:00 AM

Welcome and Opening Address

Brent M Egan, Greenvile, SC

9:15 AM

Kelsey Siebold - Houston, TX

Olethia Chisholm, Houston, TX

9:25 AM

Banner Health - Phoenix AX

Todd Hurst

9:35 AM

Trinity Health of New England

Daniel Weiswasser

9:45 AM

Q & A

# Cardiovascular Seminar

## IM.CVS.307 - The FDA Warning about Gadolinium-Based Contrast Agents: Are there Real Concerns?

#### 108B

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Garth Beache

9:00 AM

Moderator

Vincent B Ho, Bethesda, MD

9:00 AM

Gadolinium-Based Contrast Agents: Are There Really Any Differences?

sheela agarwal, whippany, NJ

10:00 AM

Panel Discussion

# FIT Event

## FIT.05 - "FIT Researcher": How To Do It All In Training

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Monday, November 18, 2019, 9:00 AM - 9:45 AM

This is not a CME/CE certified session

# Frontiers in Science

## AT.FIS.338 - Frontiers in Thrombosis: Bridging Innate Immunity and Thrombosis

#### 126B

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Nigel Mackman, Chapel Hill, NC

9:00 AM

Moderator

Lalitha Nayak, Cleveland, OH

9:00 AM

Immune Functions of Platelets

Craig Morrell, Rochester, NY

9:10 AM

Q&A

9:15 AM

Platelet PDI in ThromboInflammation

Jaehyung Cho, Chicago, IL

9:25 AM

Q&A

9:30 AM

Oxidative Mechanisms in Vascular Inflammation and Thrombosis

Tatiana V Byzova, Cleveland, OH

9:40 AM

Q&A

9:45 AM

Neutrophils, NETs and Thrombosis

Lalitha Nayak, Cleveland, OH

9:55 AM

Q&A

10:00 AM

Platelets, NETs, and Cancer-associated Thrombosis

Anna-Karin Olsson

10:10 AM

Q&A

# Joint Sessions

## CS.JS.1679 - Transatlantic Perspective on Unanswered Questions in Cardiac Critical Care: Joint AHA/ESC-ACCA

#### 120A

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

David A Morrow, Boston, MA

9:00 AM

Moderator

Susanna Price, London, United Kingdom

9:00 AM

Panel Participant

L Kristin K Newby, Durham, NC

9:00 AM

Panel Participant

Sean Van Diepen, Edmonton, AB, Canada

9:00 AM

Panel Participant

Christian Hassager, Copenhagen, Denmark

9:00 AM

Panel Participant

Holger Thiele, Leipzig, Germany

9:00 AM

Top 5 Most Important Recent Studies for the CICU Practitioner

Jason N Katz, Chapel Hill, NC

9:10 AM

How Should You Structure Delivery of Cardiac Critical Care in 2020? - Views from both sides of the Atlantic: North American Perspective

Carlos Alviar, NY

9:20 AM

How Should You Structure Delivery of Cardiac Critical Care in 2020? - Views from both sides of the Atlantic: European Perspective

Susanna Price, London, United Kingdom

9:30 AM

Panel Discussion

9:38 AM

Rapid-Fire debate: Controversies in Management of Post-Cardiac Arrest Syndrome

9:43 AM

Don't Waste Your Time, Angiography Should Be Deferred

Holger Thiele, Leipzig, Germany

9:48 AM

Ischemia, Ischemia, Ischemia: I Would Still Cath Early

Ann Gage, OH

9:53 AM

Save-the-Brain: Target MAP Should Be 75 mmHg After Cardiac arrest (Pro)

Erin A Bohula, Boston, MA

9:58 AM

Save-the-Brain: Target MAP Should Be 75 mmHg After Cardiac arrest (Con)

Christian Hassager, Copenhagen, Denmark

10:03 AM

Panel Discussion

# Late-Breaking Science

## LBS.06 - Late Breaking Science VI: New Frontiers in Lipid Therapy

#### Main Event I

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Jennifer G Robinson, Iowa City, IA

9:00 AM

Moderator

Alan S Brown, Park Ridge, IL

9:00 AM

Social Media Moderator

Samia Mora, Boston, MA

9:00 AM

Effect of Icosapent Ethyl on Progression of Coronary Atherosclerosis in Patients With Elevated Triglycerides (200-499mg/dl) on Statin Therapy (EVAPORATE Study)

**Matthew J Budoff** , Lundquist Inst and UCLA Sch of Med, Torrance, CA; Joseph Brent Muhlestein, Intermountain Heart Inst, Intermountain Medical Ctr, Salt Lake City, UT; Deepak L Bhatt, Brigham and Women's Hosp, Boston, MA; Viet T Le, Heidi T May, Intermountain Heart Inst, Intermountain Medical Ctr, Salt Lake City, UT; Kashif Shaikh, Chandana Shekar, Lundquist Inst and UCLA Sch of Med, Torrance, CA; April Kinninger, LABIOMED, Torrance, CA; Suvasini Lakshmanan, Sion Roy, John Tayek, Lundquist Inst and UCLA Sch of Med, Torrance, CA; John R Nelson, California Cardiovascular Inst, Fresno, CA

9:10 AM

Discussant

Stephen Nicholls, Hyde Park, Australia

9:14 AM

Leveraging Genomic Discovery for Novel Therapeutics

Daniel J Rader, Philadelphia, PA

9:24 AM

Safety and Efficacy of Inclisiran in Patients With Heterozygous Familial Hypercholesterolemia - Results From the Phase 3 ORION-9 Trial

**Frederick J Raal** , Johannesburg Hosp, Johannesburg, South Africa; Kausik K Ray, Imperial Coll London, London, United Kingdom; David Kallend, The Meds Company, Morristown, NJ; Wolfgang Koenig, Univ of Ulm Medical Ctr, Ulm, Germany; R. Scott Wright, Mayo Clinic, Rochester, MN; Lawrence A. Leiter, Univ of Toronto, Toronto, ON, Canada; Peter L. Wijngaard, The Meds Company, Parsippany, NJ; Johannes JP Kastelein Jr., Academic Medical Ctr, Amsterdam, Netherlands

9:32 AM

RNA Interference Targeting Apolipoprotein C-III Results in Deep and Prolonged Reductions in Plasma Triglycerides

**Christian Schwabe** , Auckland Clinical Studies, Auckland, New Zealand; Russell Scott, Christchurch Hosp, Christchurch; David R Sullivan, Auckland Clinical Studies, Camperdown, Australia; John Baker, Middlemore Hosp, Auckland, New Zealand; Peter Clifton, Univ of SA, Adelaide, Australia; James Hamilton, Bruce Given, Stacey Melquist, Arrowhead Pharmaceuticals, Pasadena, CA; Josh Knowles, Falk CVRC, Stanford, CA; Robert A Hegele, Robarts Res Inst, London, ON, Canada; Christie M Ballantyne, Baylor Coll Med, Houston, TX

9:38 AM

RNA Interference Targeting Hepatic Angiopoietin-Like Protein 3 Results in Prolonged Reductions in Plasma Triglycerides and LDL-C in Human Subjects

**Gerald F Watts** , Univ of Western Australia, Royal Perth Hosp, Perth, Australia; Christian Schwabe, Auckland Clinical Studies, Auckland, New Zealand; Russell Scott, Christchurch Hosp, Christchurch; Patrick Gladding, Auckland City Hosp, Auckland; David R Sullivan, Royal Prince Alfred Hosp, Camperdown, Australia; John Baker, Middlemore Hosp, Auckland, New Zealand; Peter Clifton, Univ of SA, Adelaide, Australia; James Hamilton, Bruce Given, Stacey Melquist, Arrowhead Pharmaceuticals, Pasadena, CA; Josh Knowles, Falk CVRC, Stanford, CA; Robert A Hegele, Robarts Res Inst, London, ON, Canada; Christie M Ballantyne, Baylor Coll Med, Houston, TX

9:44 AM

Discussant: What We Learned

Daniel J Rader, Philadelphia, PA

9:49 AM

Benefit of a Target LDL Cholesterol Less Than 70 mg/dl After an Ischemic Stroke of Atherosclerotic Origin, the Treat Stroke to Target Trial Results

**Pierre Amarenco** , Paris Univ, Paris, France; Jong S Kim, Asan Medical Ctr, Seoul; Julien Labreuche, Lille Univ, Paris, France; Hugo Charles, Paris Univ, Paris, France; Maurice Giroud, Dijon Univ, Dijon, France; Byung-Chul Lee, Hallym Univ Sacred Heart Hosp, Anyang, Korea, Republic of; Marie-Helene Mahagne, Nice Univ, Nice, France; Norbert Nighoghossian, Hop Neurologique, Bron, France; Philippe Gabriel Steg, Hop Bichat, Paris, France; Pierre-Jean Touboul, Paris Univ, Paris, France; Eric Vicaut, -, Paris, France; Eric Bruckert, Sorbonne Univ, Paris, France; Treat Stroke to Target trial Investigators

9:59 AM

Discussant

Mitchell S Elkind, New York, NY

10:03 AM

Q&A

# Main Event

## IM.ME.1762 - Quality in Cardiovascular Imaging – Session Honoring Research Contributions from CV Imaging Leaders

#### Main Event II

### Monday, November 18, 2019, 9:00 AM - 10:15 AM

9:00 AM

Moderator

Richard Kovacs, Indianapolis, IN

9:36 AM

Improving CV Imaging through Policy and Systems

Ritu Sachdeva, Atlanta, GA

9:48 AM

Panel Participant

Ritu Sachdeva, Atlanta, GA

# Women's Professional Development

## WPD.04 - Sponsor -vs- Mentor with Emelia Benjamin, MD, ScM, FAHA

#### Go Red Women in Science & Medicine Lounge, Pennsylvania Convention Center, 2nd Floor, Heart Hub

### Monday, November 18, 2019, 9:00 AM - 9:45 AM

This is not a CME/CE certified session

# Hall

## EP.HT.06 - Sudden Cardiac Death: Ask the Experts

#### EP Central

### Monday, November 18, 2019, 9:30 AM - 10:15 AM

9:30 AM

Moderator

Valentina Kutyifa, Rochester, NY

9:30 AM

Moderator

Stacy Westerman, GA

9:30 AM

Panel Participant

Lee L Eckhardt, Madison, WI

9:30 AM

Panel Participant

Selcuk Adabag, Minneapolis, MN

10:10 AM

Panel Discussion

# FIT Event

## FIT.11 - Mastering the Fellow-to-Faculty Transition

#### EC & FIT Lounge, Heart Hub, Science & Technology Hall

### Monday, November 18, 2019, 10:00 AM - 10:45 AM

This is not a CME/CE certified session

# Expert Theater

## ET.22 - Boehringer Ingelheim Corporation

#### Learning Studio 1, Booth # 5

### Monday, November 18, 2019, 10:15 AM - 11:00 AM

This is not a CME/CE certified session

# Expert Theater

## ET.23 - HOLD- TWells

#### Heart Theater, Booth # 17

### Monday, November 18, 2019, 10:15 AM - 11:00 AM

This is not a CME/CE certified session

# Expert Theater

## ET.24 - The Medicines Company

#### Learning Studio 2, Booth # 7

### Monday, November 18, 2019, 10:15 AM - 11:00 AM

This is not a CME/CE certified session

# Abstract Rapid Fire Oral

## CE.RFO29 - Epigenetics and Gene Regulation

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 10:30 AM - 11:20 AM

10:30 AM

Moderator

Sarah Franklin, Salt Lake Cty, UT

10:30 AM

Modulation of the Sumoylation of Fish Oil Receptor G-protein Coupled Receptor (gpr) 120 by Amp-activated Protein Kinase α2 Controls the Anti-atheroscleroticmodulation of the Sumoylation of Fish Oil Receptor G-protein Coupled Receptor (gpr) 120 by Amp-activated Protein Kinase α2 Controls the Anti-atherosclerotic Effects of Fish Oils in Vivomodulation of the Sumoylation of Fish Oil Receptor G-protein Coupled Receptor (gpr) 120 by Amp-activated Protein Kinase α2 Controls the Anti-atherosclerotic Effects of Fish Oils in vivo

**Cheng Hui Yan** , General Hosp of Shenyang Military Region, Shenyang, China

10:35 AM

Q & A

10:40 AM

The Lysine Methyltransferase Smyd1 Regulates Purine Metabolism in the Heart

Marta W Szulik, Univ of Utah, Salt Lake City, UT; Chris Tracy, Magnus Creed, Univ of Utah, Salt Lake Cty, UT; Aman Makaju, Univ of Utah, Salt Lake City, UT; Junco S Warren, **Sarah Franklin** , Univ of Utah, Salt Lake Cty, UT

10:45 AM

Q & A

10:50 AM

Enhanced Glutaminolysis Links Metabolism to the Epigenetic Modifications Required for Myofibroblast Differentiation and Persistence During Stress

**Andrew A Gibb** , Emma K Murray, Alyssa L Lombardi, Temple Univ, Philadelphia, PA; Pawel K Lorkiewicz, Univ of Louisville, Louisville, KY; Anh T Huynh, Devin W Kolmetzky, Temple Univ, Philadelphia, PA; Zoltan P Arany, Daniel P Kelly, Kenneth B Margulies, Univ of Pennsylvania, Philadelphia, PA; Bradford G Hill, Univ of Louisville, Louisville, KY; John W Elrod, Temple Univ, Philadelphia, PA

10:55 AM

Q & A

11:00 AM

Acetylation of Histone H3 Globular Domain is Involved in p300/BRG1 Complex During the Development of Heart Failure

**Masafumi Funamoto** , Yoichi Sunagawa, Yasufumi Katanasaka, Kana Shimizu, Yusuke Miyazaki, Satoshi Shimizu, Univ of Shizuoka, Shizuoka, Japan; Hiromichi Wada, Natl Hosp Org Kyoto Medical Ctr, Kyoto, Japan; Koji Hasegawa, Kyoto Medical Ctr NHO, Kyoto, Japan; Tatsuya Morimoto, Univ of Shizuoka, Shizuoka, Japan

11:05 AM

Q & A

11:10 AM

Comparison Between Ultrastructural Features and Causative Genes of Dilated Cardiomyopathy Detected by Whole Exome Sequencing

**Tsunenori Saito** , Nippon Medical Sch Tama-Nagayama Hosp, Tokyo, Japan; Kuniya Asai, Nippon Medical Sch Chiba Hokusoh Hosp, Chiba, Japan; Naoko Saito-Sato, Japanese Red Cross Medical Ctr, Tokyo, Japan; Kosuke Mozawa, Eiichiro Oka, Nippon Medical Sch, Tokyo, Japan; Shigeru Sato, Tokyo Electron Microscopy Lab, Chiba, Japan; Kyoichi Mizuno, Nippon Medical Sch, Tokyo, Japan; Roberta A Gottlieb, Cedars-Sinai Medical Ctr, Los Angeles, CA; Wataru Shimizu, Nippon Medical Sch, Tokyo, Japan

11:15 AM

Q & A

# Abstract Rapid Fire Oral

## QU.RFO38 - Improving Outcomes of Acute Coronary Syndromes

#### Science and Technology Hall A, Booth 605, Level 2

### Monday, November 18, 2019, 10:30 AM - 11:20 AM

10:30 AM

**Non-Thrombotic Troponin Elevation:** More Than That Meets The Coders' Eye

**Varun Kumar** , Mount Sinai Hosp Medical Ctr, Chicago, IL; Lakshmi Gopalakrishnan, Sinai Health System, Chicago, IL; Sandeep M Khosla, Mount Sinai Hosp Medical Ctr, Chicago, IL

10:40 AM

Catheterization Laboratory Activation Time: A Novel Metric for Faster Reperfusion in STEMI Transfers - Insights From the Accelerator-2 Project

**Michel Zeitouni** , Duke Clinical Res Inst, Durham, NC; Hussein Al-Khalidi, Duke Univ, Durham, NC; Shannon M Doerfler, Duke Clinical Res Inst, Durham, NC; Mayme L Roettig, Duke Univ, Chapel Hill, NC; Timothy D Henry, Cedars Sinai Medical Ctr, Cincinnati, OH; B.Hadley Wilson, Sanger Heart and Vascular Inst, Charlotte, NC; Khaled Ziada, Clark Regional Medical Ctr, Lexington, KY; Christopher Bull Granger, Duke Clinical Res Inst, Durham, NC; James Jollis, Duke Univ, Durham, NC

10:50 AM

Radial versus Femoral Access for Percutaneous Coronary Intervention in Patients With St-segment Elevation Myocardial Infarction: Trial Sequential Analysis

Mohammed Osman, **Maryam Saleem** , Khansa Osman, West Virginia Univ, Morgantown, WV; Babikir Kheiri, Hurley Medical Ctr, Michigan State Univ, Flint, MI; Sean Regner, West Virginia Univ, Morgantown, WV; Qais Radaideh, Midwest Cardiovascular Res Fndn, Davenport, IA; Jason A. Moreland, West Virginia Univ, Morgantown, WV; Sunil V Rao, Duke Uuniversity Medical Ctr, Durham, NC; Samir R Kapadia, Cleveland Clinic, Cleveland, OH

11:00 AM

Posttraumatic Stress Disorder After Suspected Acute Coronary Syndrome is Associated With Lower Adherence to Cardiovascular Medication

**Ian M Kronish** , Columbia Univ, New York, NY; Talea Cornelius, Columbia Univ Medical Ctr, New York, NY; Joseph E. Schwartz, Stony Brook Univ, Stony Brook, NY; Ari Shechter, Keith Diaz, Emily K Romero, Columbia Univ, New York, NY; Donald Edmondson, Columbia Univ Medical Ctr, New York, NY

11:10 AM

Breath Training Improve Quality of Life in Patients After Myocardial Infarction

**Xiaosong Gu** , 2th Affiliated Hosp of Soochow Univ, Suzhou, Jiangsu Province, China

# Abstract Rapid Fire Oral

## CH.RFO32 - Outcomes Research in Congenital Cardiology

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 10:30 AM - 11:20 AM

10:30 AM

Moderator

Sara K Pasquali, Ann Arbor, MI

10:30 AM

Environmental and Socioeconomic Factors Influence the Incidence of Congenital Heart Disease: A Population-Based Study in California

**Shabnam Peyvandi** , Univ. of California San Francisco, San Francisco, CA; Rebecca Baer, Univ of California San Diego, San Diego, CA; Christina Chambers, Univ of California San Diego, La Jolla, CA; Mary Norton, Satish Rajagopal, Univ. of California San Francisco, San Francisco, CA; Kelli Ryckman, Univ of Iowa, Iowa City, IA; Anita Moon-Grady, Laura Jelliffe-Pawlowski, Univ. of California San Francisco, San Francisco, CA; Martina Andrea Steurer, UCSF Dept of Pediatrics, San Francisco, CA

10:35 AM

Q & A

10:40 AM

The Association of Hospital Transfer on Outcomes of Newborns With Transposition of Great Arteries: Analysis of National Inpatient Sample Database Years of 2008-2016

**Hasan F. Othman** , Cleveland Clinic Children's, Cleveland, OH; Mohammed Hamzah, Cleveland clinic, Cleveland, OH; Murad Almasri, Univ of Texas Medical Branch, Galveson, TX; Hany Aly, Cleveland Clinic Children's, Cleveland, OH

10:45 AM

Q & A

10:50 AM

Interstage Monitoring is Associated With Greater Weight Gain and Oxygen Saturation Over Time: A Longitudinal Analysis of National Pediatric Cardiology-Quality Improvement Collaborative Phase 1 Data

**James M Meza** , Duke Univ Medical Ctr, Durham, NC; Eugene H Blackstone, Cleveland Clinic, Cleveland, OH; Jeevanantham Jajeswaran, The Cleveland Clinic, Cleveland, OH; Nicholas D Andersen, Holly LoTurco, Duke Univ Medical Ctr, Durham, NC; Brian W McCrindle, Hosp for Sick Children, Toronto, ON, Canada; Kristine J Guleserian, Nicklaus Children's Hosp, Miami, FL; Tara Karamlou, Cleveland Clinic, Cleveland, OH; Garick D Hill, Cincinnati Children's Hosp, Cincinnati, OH; Joseph W Turek, Duke Univ Medical Ctr, Durham, NC

10:55 AM

Q & A

11:00 AM

Impact of Tricuspid Regurgitation and Surgical Intervention for Tricuspid Regurgitation Across Staged Palliation for Single Right Ventricle Anomalies: The Single Ventricle Reconstruction Trial

**James F Cnota** , Cincinnati Childrens Hosp, Cincinnati, OH; Shahryar M Chowdhury, Medical Univ of South Carolina, Charleston, SC; Alejandro Floh, The Hosp for Sick Children, Toronto, ON, Canada; Russell Gongwer, New England Res Insts, Watertown, MA; Benjamin Goot, Children's Hosp of Wisconsin, Milwaukee, WI; Jeffrey P Jacobs, Johns Hopkins All Children's Hospit, Saint Petersburg, FL; Matthew Jolley, 1975, Merion Station, PA; Sonya Kirmani, Duke Univ, Durham, NC; Damien LaPar, Morgan Stanley Children's Hosp, New York, NY; Jami C Levine, Childrens Hosp, Boston, MA; Alan B Lewis, Childrens Hosp LA, Los Angeles, CA; Ricardo H Pignatelli, Texas Childrens Hosp, Missouri City, TX; Christian Pizarro, DuPont Hosp for Children, Wilmington, DE; Tim C Slesnick, Emory Univ, Atlanta, GA; Thor Thorsson, Univ of Michigan, Ann Arbor, MI; Felicia Trachtenberg, New England Res Insts, Watertown, MA; Dongngan Truong, Primary Children's Hosp, University of Utah, UT; Jane W Newburger, Childrens Hosp Boston, Boston, MA; Peter C Frommelt, Childrens Hosp Wisconsin, Milwaukee, WI

11:05 AM

Q & A

11:10 AM

Epidemiology of Neonatal Cardiac Surgery Induced Acute Kidney Injury From the Neonatal and Pediatric Heart and Renal Outcomes Network

**Jeffrey Alten** , Cincinnati Childrens Hosp Medical Ctr, Cincinnati, OH; David S Cooper, Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH; Katja M Gist, Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH, Denver, CO; David Selewski, Garrett Reichle, Medical Univ of South Carolin, Charleston, SC; Sarah Tabbutt, UCSF Benioff Childrens Hosp, Mill Valley, CA; Rebecca Bertrandt, Medical Coll of Wisconsin, Milwaukee, WI; Andrew Smith, Medical Coll of Wisconsin, Milwaukee, WI, Nashville, TN; Jun Sasaki, Nicklaus Children's Hosp, Miami, FL; Kristal M Hock, Nicklaus Children's Hosp, Miami, FL, Talladega, AL; Michael G Gaies, Santiago Borasino, Univ of Michigan, Ann Arbor, MI; on behalf of NEPHRON Investigators

11:15 AM

Q & A

# Abstract Rapid Fire Oral

## HF.RFO35 - Top Rated Abstracts in Heart Failure: Predictors and Biomarkers

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 10:30 AM - 11:20 AM

10:30 AM

Moderator

Eileen M Hsich, Cleveland, OH

10:30 AM

Predictors of End-Stage Hypertrophic Cardiomyopathy

**Peter Marstrand** , Neal K Lakdawala, Brigham and Women's Hosp, Boston, MA; Sharlene M Day, Univ of Pennsylvania, Philadelphia, PA; Euan A Ashley, Stanford Univ, Stanford, CA; Michelle Michels, Erasmus MC Rotterdam, Rotterdam, Netherlands; Alexandre Pereira, Heart Inst (incor), Sao Paulo, Brazil; Samuel Wittekind, Cincinnati Children's, Cincinnati, OH; Daniel Jacoby, Yale Sch of Med, New Haven, CT; James Simon Ware, Imperial Coll London, London; Steven Colan, Boston Children's Hosp, Boston, MA; Iacopo Olivotto, Careggi Univ Hosp, Florence, Italy; Christopher Semsarian, Centenary Inst, Newtown, Australia; Jodie Ingles, Centenary Inst, Sydney, Australia; Carolyn Ho, Brigham and Women's Hosp, Boston, MA

10:35 AM

Q & A

10:40 AM

Cathepsin-D and Outcomes in Peripartum Cardiomyopathy: Results From IPAC

**Vincenzo B Polsinelli** , Karen Hanley-Yanez, Charles F McTiernan, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Uri Elkayam, Univ of Southern California, Los Angeles, CA; Leslie T Cooper, Mayo Clinic, Jacksonville, FL; James D Fett, Univ of Pittsburgh & Albert Schweitzer Hosp Haiti, Pittsburgh, PA; Dennis M McNamara, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA

10:45 AM

Q & A

10:50 AM

N8-Acetylspermidine: A Novel Biomarker for the Development and Progression of Ischemic Cardiomyopathy

**Aditi Nayak** , Chang Liu, Emory Univ, Atlanta, GA; Anurag Mehta, Emory Univ Sch of Med, Atlanta, GA; Yi-An Ko, Ayman S Tahhan, Devinder Singh Dhindsa, Karan Uppal, Dean Jones, Emory Univ, Atlanta, GA; Javed Butler, Univ of Mississippi Medical Ctr, Jackson, MS; Alanna A Morris, Emory Univ Sch Med, Atlanta, GA; Arshed A Quyyumi, Emory Univ, Atlanta, GA

10:55 AM

Q & A

11:00 AM

Event-prediction of Right Ventricular to Pulmonary Circulation Coupling Measured During Exercise in Patients With Heart Failure

**Tadafumi Sugimoto** , MIE Univ, Tsu, Japan; Francesco Bandera, IRCCS Policlinico San Donato, Varese, Italy; Greta Generati, IRCCS Policlinico San Donato, San Donato Milanese, Italy; Eleonora Alfonzetti, Univ of Milano, Milano, Italy; valentina labate, IRCCS Policlinico San Donato Milanese, San Donato, Italy; Marco Guazzi, IRCCS Policlinico San Donato, Milano, Italy

11:05 AM

Q & A

11:10 AM

Detection of Asymptomatic Left Ventricular Systolic Dysfunction in a Community-Based Cohort: Artificial Intelligence Augmented Electrocardiogram versus N-Terminal Pro-B-Type Natriuretic Peptide

**Anthony Kashou** , Mayo Clinic, Rochester, MN; Francisco Lopez-Jimenez, Mayo Clinic Coll Med, Rochester, MN; Peter Alexander Noseworthy, Itzhak Z Attia, Suraj Kapa, Christopher Scott, Richard J Rodeheffer, Alexander T Lee, Paul Friedman, Paul M McKie, Mayo Clinic, Rochester, MN

11:15 AM

Q & A

# Moderated Digital Posters

## HF.MDP49 - Can We Find Targets for Medical Therapy of Valvular Heart Disease?

#### Moderated Posters 1, Science and Technology Hall

### Monday, November 18, 2019, 10:30 AM - 11:20 AM

10:30 AM

ANGPTL2 is Essential to the Aortic Valve Structure and Function by Regulating the Notch1 Pathway

**Pauline Labbé** , Louis Villeneuve, Mélanie Mecteau, Jean-Claude Tardif, Nathalie Thorin-Trescases, Eric Thorin, Montreal Heart Inst, Montreal, QC, Canada

10:35 AM

Q & A

10:40 AM

Developmental Processes Mediate Mitral Valve Elongation in Hypertrophic Cardiomyopathy

**Aaron Troy** , Navneet Narula, Luis Chiriboga, Andre Moreira, Alexandra Stepanovic, Kristen Thomas, Briana Zeck, NYU Sch of Med, New York, NY; Iacopo Olivotto, Careggi Univ Hosp, Florence, Italy; Daniel G Swistel, Mark V Sherrid, NYU Sch of Med, New York, NY

10:45 AM

Q & A

10:50 AM

Pharmacological Strategy to Prevent Ischemic Mitral Regurgitation: Serotonin as a New Therapeutic Target

**Ons Marsit** , Inst Univire de Cardiologie et de pneumologie de Quebec, Quebec, QC, Canada; Marie Annick Clavel, Quebec Heart Inst, Quebec, QC, Canada; Marc-Andre Bouchard, Inst Univire de Cardiologie et de pneumologie de Quebec, Quebec, QC, Canada; Marine Clisson, Quebec Heart Inst, Québec, QC, Canada; Mark D. Handschumacher, Harvard Medical Sch, Boston, Boston, MA; Marie-Claude Drolet, Amelie Paquin, Inst Univire de Cardiologie et de Pneumologie de Quebec, Quebec, QC, Canada; Sandra Hadjadj, Inst Univire de Cardiologie et de Pneumolgie de Quebec, Québec, QC, Canada; Jacques Couet, Inst Univire de Cardiologie et de Pneumolgie de Quebec, Quebec, QC, Canada; Marie Arsenault, Inst Univire de cardiologie et de pneumologie de Québec, Sainte-Foy, QC, Canada; Philippe Pibarot, IUCPQ-UL, Quebec, QC, Canada; Robert A. Levine, Harvard Medical Sch, Boston, Boston, MA; Jonathan Beaudoin, Inst Univire de Cardiologie et de Pneumolgie de Quebec, Quebec, QC, Canada

10:55 AM

Q & A

11:00 AM

Advanced Glycation End Products Formation Drives Structural Bioprosthetic Valve Degeneration

**Yingfei Xue** , Columbia Univ, New York, NY; Antonio Frasca, Columbia Univ Medical Ctr, New York, NY; Samuel Keeney, Andrey Zakharchenko, Children's Hosp of Philadelphia, Philadelphia, PA; Alexander Kossar, Columbia Univ, New York, NY; Robert Levy, Children's Hosp of Philadelphia, Philadelphia, PA; Giovanni Ferrari, Columbia Univ, New York, NY

11:05 AM

Q & A

11:10 AM

Transforming Growth Factor-β Pathway Gene Expression Changes in an Ovine Model of Ischemic Mitral Regurgitation

**Estibaliz Castillero** , Columbia Univ Irving Medical Ctr, New York, NY; Daniel P Howsmon, Bruno V Rego, Univ of Texas at Austin, Austin, TX; Yingfei Xue, New york, NY; Robert C Gorman, Univ of Pennsylvania, Philadelphia, PA; Michael S Sacks, Univ of Texas at Austin, Austin, TX; Robert Levy, Univ of Texas at Austin, Austin, TX, Merion Sta, PA; Giovanni Ferrari, Columbia Univ Irving Medical Ctr, New York, NY

11:15 AM

Q & A

# Moderated Digital Posters

## GE.MDP64 - Genome Editing to Validate Cardiovascular Targets

#### Moderated Posters 6, Science and Technology Hall

### Monday, November 18, 2019, 10:30 AM - 11:20 AM

10:30 AM

Atrial Fibrillation Associated Common Risk Variants in SYNE2 Lead to Lower Expression of Nesprin-2A1 and Increased Nuclear Stiffness

**Nana Liu** , Jeffrey Hsu, Cleveland Clinic, Cleveland, OH; Gautam Mahajan, Cleveland State Univ, Cleveland, OH; John Barnard, David Von Vagoner, Mina Chung, Cleveland Clinic, Cleveland, OH; Chandrasekhar Kothapalli, Cleveland State Univ, Cleveland, OH; Jonathan D Smith, Cleveland Clinic Fndn, Cleveland, OH

10:35 AM

Q & A

10:40 AM

Transforming Growth Factor-β Type 1 Receptor Gene Mutations Impairs Cardiovascular Progenitor Cell-derived Smooth Muscle Cells Differentiation From Human Induced Pluripotent Stem Cells

Dong Zhou, Ping QIU, Jie Xu, Univ of Michigan, Ann Arbor, MI; Eugene Chen, UNIV OF MICHIGAN MEDICAL CTR, Ann Arbor, MI; **Bo Yang** , Univ of Michigan, Ann Arbor, MI

10:45 AM

Q & A

10:50 AM

**Characterization of a Novel Homozygous Multi-exon** Ryr2 **Duplication Associated With Exertion-related Sudden Unexplained Death in the Young in the Amish Community Using Patient-specific Hipsc-cardiomyocytes**

**David J Tester** , CS John Kim, Samantha K Hamrick, Mayo Clinic Coll of Med, Rochester, MN; Hannah M Bombei, Univ of Iowa, Iowa City, IA; Kristi K Fitzgerald, Nemours, Alfred I DuPont Hosp for Children, Wilmington, DE; Carla M Haglund-Turnquist, Mayo Clinic Coll of Med, Rochester, MN; Dianne L Atkins, Luis A Ochoa, Univ of Iowa, Iowa City, IA; Ian H Law, Univ of Iowa Children's Hosp, Iowa City, IA; Joel Temple, Nemours, Alfred I DuPont Hosp for Children, Wilmington, DE; Michael John Ackerman, Mayo Clinic Coll of Med, Rochester, MN

10:55 AM

Q & A

11:00 AM

Intrinsic Activation of Cardiomyocyte Differentiation Factors in Cdcs in Myocardial Infarctions Using Crispr-dcas9

**Toshikazu Sano** , Univ of California, San Francisco, San Francisco, CA; Shuta Ishigami, UCSF, San Francisco, CA; Srinivas Bandaru, Tatsuo Ito, Okayama Univ Graduate Sch of Med, Okayama, Japan; Shunji Sano, Univ of California, San Francisco, San Francisco, CA

11:05 AM

Q & A

11:10 AM

Nexilin Mutation Impairs LV Compensatory Ability to Pressure Overload in Mice

Jianping Li, Baylor Coll Med, Houston, TX; Wenxin Zou, Baylor Coll of Med, Houston, TX; Ruirui Ji, Houston Methodist Hosp, Houston, TX; Yutao Xi, Texas Heart Inst, Houston, TX; Lianghao Lu, Daniel J Penny, **Yuxin Fan** , Baylor Coll Med, Houston, TX

11:15 AM

Q & A

# Moderated Digital Posters

## IM.MDP55 - Heard on the Beat: Advances in MRI of Ischemic Heart Disease

#### Moderated Posters 3, Science and Technology Hall

### Monday, November 18, 2019, 10:30 AM - 11:20 AM

10:30 AM

Manganese-enhanced MRI Detects the Peri-infarct Region of the Ischemic Cardiomyopathy Patients

**Yuko Tada** , Michelle Santoso, Shahriar Heidary, Stanford Univ, Stanford, CA; Phillip Harnish, Eagle Vision Pharmaceutical Corp, Palo Alto, CA; Phillip C Yang, Stanford Univ, Stanford, CA

10:35 AM

Q & A

10:40 AM

Ferumoxytol-Enhanced T1-Mapping Provides Superior Contrast in Regions of Myocardial Ischemia

**Caroline M Colbert** , Jiaxin Shao, UCLA, Los Angeles, CA; Jesse Currier, VA Medical Ctr West LA, Los Angeles, CA; Olujimi A Ajijola, Peng HU, UCLA, Los Angeles, CA; Kim-Lien Nguyen, UCLA and VA GLAHS, Los Angeles, CA

10:45 AM

Q & A

10:50 AM

Prognostic Significance of Global Extracellular Volume Evaluated by Cardiac Magnetic Resonance Imaging for Patients With Acute Myocardial Infarction

**Masaki Ishiyama** , Tairo Kurita, Mie Univ, Tsu, mie, Japan; Taku Omori, Mie Univ Hospiital, Mie Tsu, Japan; Shiro Nakamori, Mie Univ, Tsu, mie, MA; Masaki Ishida III, Mie Univ Hosp, Tsu, Mie, Japan; Naoki Fujimoto, Mie Univ Graduate Sch Med, Tsu, Japan; Kakuya Kitagawa, Mie Univ, Tsu, Japan; Hajime Sakuma, Mie Univ Hosp, Tsu, Mie, Japan; Masaaki Ito, Mie Univ Graduate Sch Of Med, Tsu-shi, Japan; Kaoru Dohi, Mie Univ Graduate Sch of Med, Tsu, Japan

10:55 AM

Q & A

11:00 AM

Myocardial Ischemia Indexed as High-sensitivity Cardiac Troponin T is Associated With Mri Defined Myocardial Interstitial Fibrosis: the Multi-Ethnic Study of Atherosclerosis

**Olusayo Olutunde Fadiran** , Howard Univ Hosp, Washington, DC; Mohammad Ostovaneh, Johns Hopkins Medical Insts, Baltimore, MD; Christopher Defilippi, Inova, Falls Church, VA; Bharath Ambale-Venkatesh, Yoko Kato, John Hopkins Univ, Baltimore, MD; Hooman Bakhshi, Medstar Union Memorial Hosp, Timonium, MD; Russell Tracy, Univ Vermont, Colchester, VT; Colin O Wu, Natl Heart, Lung and Blood Inst, Bethesda, MD; David Bluemke, UW Madison Hosp, Madison, WI; Joao Lima, Johns Hopkins Univ, Baltimore, MD

11:05 AM

Q & A

11:10 AM

Architectural Protection From Ischemia-Reperfusion Injury is Afforded by Ablation of the Calpain Targeting Site of Myosin Binding Protein-c in the Mouse Myocardium

**Owen P Leary** , Dana Leichter, Providence VA Medical Ctr, Providence, RI; James W McNamara, Univ of Cincinnati, Cincinnati, OH; Michelle L Nieman, Univ of Cicinatti, Cincinatti, OH; John Lorenz, Univ of Cincinatti, Cincinatti, OH; Sakthivel Sadayappan, Univ of Cincinnati, Cincinnati, OH; Richard J Gilbert, Providence VA Medical Ctr, Providence, RI

11:15 AM

Q & A

# Moderated Digital Posters

## MP.MDP58 - Metabolism

#### Moderated Posters 4, Science and Technology Hall

### Monday, November 18, 2019, 10:30 AM - 11:20 AM

10:30 AM

Short Chain Fatty Acid Oxidation Outpaces Ketone Oxidation for Energy Production in Failing Hearts

**Andrew N Carley** , Srividya Murali, Matthew Fasano, Santosh K Maurya, E. Douglas Lewandowski, The Ohio State Univ Wexner Medical Ctr, Columbus, OH

10:35 AM

Q & A

10:40 AM

Cardiac Expression of BARKnt May Reveal Novel Link Between Heart and Systemic Metabolism

**Iyad H Manaserh** , Kamila Bledzka, Cleveland Clinic, Cleveland, OH; Jessica M Pfleger, Temple Univ, Philadelphia, PA; Jessica Grondolsky, Sarah M Schumacher, Cleveland Clinic, Cleveland, OH

10:45 AM

Q & A

10:50 AM

Cardiac Hypertrophy and Altered Glycolytic Metabolism are Reversed in an Aortic Constriction Mice Model

**Leonardo Jensen** , Insto do Coracao (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, Univ de Sao Paulo, Sao Paulo, Brazil; Amanda Silva, Insto do Coracao (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, Univ de Sao Paulo, São Paulo, Brazil; Daniele Faria, Faculdade de Medicina - USP, São Paulo, Brazil; Gabriela Venturini, Alexandre Pereira, Insto do Coracao (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, Univ de Sao Paulo, Sao Paulo, Brazil; Carlos Alberto Buchpiguel, Hosp das Clinicas HCFMUSP, Faculdade de Medicina, Univ de Sao Paulo, Sao Paulo, Brazil; Maria Claudia C Irigoyen, Heart Inst, Sao Paulo, Brazil

10:55 AM

Q & A

11:00 AM

Sirt6 Overexpressing Transgenic Mice Are Protected From Developing Nutritional Overload Mediated Obesity and Diabetic Cardiomyopathy

Abhinav Kanwal, Manipal Coll of Pharmaceutical Sciences, Manipal, India; **Vinod Kumar Bhaskara Pillai** , Univ of Chicago, Chicago, IL; Sadhana A Samant, The Univ of Chicago, Chicago, IL; Madhu Gupta, Mahesh P Gupta, Univ of Chicago, Chicago, IL

11:05 AM

Q & A

11:10 AM

NAD Redox Imbalance Accelerates Diabetic Cardiomyopathy: Roles of NAD Metabolism, Protein Modifications and Oxidative Stress

Ying Ann Chiao, Oklahoma Med Res Fndn, Oklahoma City, OK; Christine Light, Huyen Tran, Oklahoma Medical Res. Fndn, Oklahoma City, OK; Rong Tian, Univ Washington, Seattle, WA; Junichi Sadoshima, Rutgers New Jersey Medical Sch, Neweark, NJ; **Chi Fung Lee** , Oklahoma Medical Res. Fndn, Oklahoma City, OK

11:15 AM

Q & A

# Moderated Digital Posters

## CM.MDP61 - Metabolism 2

#### Moderated Posters 5, Science and Technology Hall

### Monday, November 18, 2019, 10:30 AM - 11:20 AM

10:35 AM

Q & A

10:40 AM

The Phase of Second Harmonic of Radial Pulse Wave Predicts the Macrovascular and Microvascular Outcomes and Mental Disorder in Asymptomatic Patients With Type 2 Diabetes

**Chi-Wei Chang** , Mii-Ann Medical Ctr, Taipei, Taiwan; Kuomeng Liao, Zhongxiao Branch of Taipei City Hosp, Taipei, Taiwan; Yi-Ting Chang, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Sheng-Hung Wang, Mii-Ann Medical Ctr, Taipei, Taiwan; Ying chun Chen, Zhongxiao Branch of Taipei City Hosp, Taipei, Taiwan; gin-chung wang, JinMu Health Technology, Taipei, Taiwan

10:45 AM

Q & A

10:50 AM

Empagliflozin Improves Heart Failure Caused by Pressure Overload by Regulating Cardiac Metabolism

**Xuan Li** , Univ of Mississippi Medical Ctr, Jackson, MS; Jia Liu, Di Ren, Jingwen Zhang, Ying Han, Ji Li, Univ of South Florida, Tampa, FL

10:55 AM

Q & A

11:00 AM

Decrease in Endothelial Mitochondrial Oxidants Improves Post-Myocardial Infarction Cardiac Function Through Activation of Angiogenesis Induced by Increase in Fatty Acid Oxidation

**Rayane Brinck Teixeira** , Brown Univ Warren Alpert Medical Sch, Providence, RI; Melissa Pfeiffer, Brown Univ, Providence, RI; Peng Zhang, Rhode Island Hosp, Providence, RI; Frank W Sellke, Brown Medical Sch, Providence, RI; Ruhul Abid, Brown Univ Warren Alpert Med, Providence, RI

11:05 AM

Q & A

11:10 AM

Mitochondrial Transplantation Into Cardiomyocytes Leads to Transient Enhanced Bioenergetics

**Paria Ali Pour** , M. Cristina Kenney, Arash Kheradvar, Univ of California Irvine, Irvine, CA

11:15 AM

Q & A

# Moderated Digital Posters

## EP.MDP67 - Novel Approaches to Predicting the Risk of Heart Failure with Preserved Ejection Fraction

#### Moderated Posters 7, Science and Technology Hall

### Monday, November 18, 2019, 10:30 AM - 11:20 AM

10:30 AM

Moderator

Yogesh Reddy, Rochester, MN

10:30 AM

Echocardiographic Correlates of Coronary Artery Disease and Subsequent Incident Heart Failure With Preserved Ejection Fraction: The Aric Study

**Jenine E John** , Brian Claggett, Hicham Skali, Brigham and Women's Hosp, Boston, MA; Scott D Solomon, Brigham and Womens Hosp, Boston, MA; Jonathan Cunningham, Brigham and Women's Hosp, Boston, MA; Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD; Suma H Konety, Univ Minnesota, Minneapolis, MN; Dalane Kitzman, Wake Forest Baptist Health, Winston-Salem, N.C. 27157, NC; Thomas Mosley, Univ MS Medical Ctr, Jackson, MS; Donald CLARK III, Univ of Mississippi, Jackson, MS; Patricia Chang, Univ of North Carolina, Chapel Hill, NC; Amil M Shah, Brigham and Women S Hosp, Boston, MA

10:35 AM

Q & A

10:40 AM

**The H** 2 **FPEF Score Predicts Exercise Capacity in People at Risk for Heart Failure (Stage A)**

**Katlyn Koepp** , Mayo Clinic, Rochester, MN; Thomas P Olson, Mayo Clinic-Rochester, Rochester, MN; Masaru Obokata, Yogesh Reddy, Alexander C Egbe, Joshua Smith, Barry A Borlaug, Mayo Clinic, Rochester, MN

10:45 AM

Q & A

10:50 AM

Application of the H2FPEF-score to the Community: The Aric Study

**Senthil Selvaraj** , Univ of Pennsylvania, Philadelphia, PA; Peder Myhre, Akershus Univ Hosp and Univ of Oslo, Oslo, Norway; Muthiah Vaduganathan, Brigham and Women's Hosp, Cambridge, MA; Brian Claggett, Amil M Shah, Scott D Solomon, Brigham and Women's Hosp, Boston, MA

10:55 AM

Q & A

11:00 AM

Atrial Fibrillation Increases Risk for 30-Day Hospital Readmission in Heart Failure With Preserved Ejection Fraction

**Eunice Yang** , Johns Hopkins Hosp, Baltimore, MD; Joban Vaishnav, Baltimore, MD; Jessica Chasler, Johns Hopkins Hosp, Baltimore, MD; Lisa R Yanek, Johns Hopkins Medical Insts, Baltimore, MD; Dhanajay Vaidya, Steve Schulman, Johns Hopkins Hosp, Baltimore, MD; Stuart D Russell, Duke Univ Medical Ctr, Raleigh, NC; Kavita Sharma, Johns Hopkins Univ SOM, Baltimore, MD

11:05 AM

Q & A

11:10 AM

Recurrent Neural Network Enhance Phenotyping in Heart Failure With Preserved Ejection Fraction Using Electronic Health Record

**Hui Ren** , Massachusetts General Hosp, Boston, MA; Wei Qiu, Peking Univ, Beijing, China; Aoxiao Zhong, Harvard Univ, Boston, MA; Sijia Yu, Xiang Li, Ning Guo, Quanzheng Li, Massachusetts General Hosp, Boston, MA

11:15 AM

Q & A

# Moderated Digital Posters

## QU.MDP70 - Vulnerable Populations and Disparities

#### Moderated Posters 8, Science and Technology Hall

### Monday, November 18, 2019, 10:30 AM - 11:20 AM

10:30 AM

Moderator

Khadijah Breathett, Tucson, AZ

10:30 AM

Scaling up a Pharmacist-Led Blood Pressure Control Program In Black Barbershops: Projecting Population Health Impact and Cost-Effectiveness

**Dhruv S Kazi** , Beth Israel Deaconess Medical Ctr, Boston, MA; Pengxiao C Wei, Univ of California San Francisco, San Francisco, CA; Brandon K Bellows, Columbia Univ Coll of Physicians and Surgeons, New York, NY; Joanne Penko, Pamela Coxson, Univ of California San Francisco, San Francisco, CA; Kelsey B Bryant, Columbia Univ Coll of Physicians and Surgeons, New York, NY; Valy Fontil, Univ of California San Francisco, San Francisco, CA; Ciantel Adair Blyler, Cedars Sinai Medical Ctr, Los Angeles, CA; Kathleen Lynch, Mohamad Rashid, Cedars Sinai, Los Angeles, CA; Joseph Ebinger, Cedars-Sinai Heart Inst, Los Angeles, CA; Florian Rader, Cedars Sinai Medical Ctr, Los Angeles, CA; Andrew E Moran, Columbia Univ Coll of Physicians and Surgeons, New York, NY; Kirsten Bibbins-Domingo, Univ of California San Francisco, San Francisco, CA

10:35 AM

Q & A

10:40 AM

Temporal Changes in Prevalence and Self-Reported Causes of Uninsurance Among Nonelderly US Adults With Atherosclerotic Cardiovascular Disease in Relation to the Affordable Care Act

**Rohan Khera** , Univ of Texas Southwestern Medical Ctr, Dallas, TX; Javier Valero-Elizondo, Yale Univ, New Haven, CT; Sandeep R Das, Univ of Texas Southwestern Med Ctr, Dallas, TX; Khurram Nasir, Yale Sch of Med, New Haven, CT

10:45 AM

Q & A

10:50 AM

Sociodemographic Disparities in Influenza Vaccination Among Adults With Atherosclerotic Cardiovascular Disease in the United States

**Gowtham R Grandhi** , MedStar Health Baltimore, Baltimore, MD; Javier Valero-Elizondo, Yale Univ, New Haven, CT; Reed Mszar, Yale Sch of Public Health, Manassas, VA; Rohan Khera, UT Southwestern Medical Ctr, Dallas, TX; Nihar R. Desai, Yale Sch of Med, New Haven, CT; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; Ron Blankstein, Brigham and Womens Hosp, Boston, MA; Salim S Virani, Michael E Debakey VA-Baylor, Bellaire, TX; Harlan M Krumholz, Yale Univ Schl Med, New Haven, CT; Saad B Omer, Emory Univ Sch of Public Health, Atlanta, GA; Khurram Nasir, Yale Sch of Med, New Haven, CT

10:55 AM

Q & A

11:00 AM

A Telemedicine-Based Program Covers Millions of Patients and Flattens Disparities in AMI Care

**Sameer Mehta** , Roberto Botelho, Jamil Cade, Marco Perin, Mauricio Prudente, Francisco Fernandez, Ricardo Cavalcanti, Rodolfo Cardoso, Fredy Bojanini, Nabil Hamdan, Cesar Dusilek, Marco Alcocer, Juan Carlos Perez Alva, Lumen Fndn, Miami, FL; Alfredo Estrada, Medica Diamante., Tuxtla Gutierrez, Chiapas, Mexico; Manuel Odin De Los Rios, Novo Nordisk, Mexico, Mexico; Alejandra Frauenfelder, Daniel Vieira, Mariana Ceschim, Rodrigo Jacobucci, Lorena Pisana, Jorge Mazzini, Maria Angelica Marin, Camila Funatsu, Isabella Vallenilla, Akhil Vaid, Lumen Fndn, Miami, FL

11:05 AM

Q & A

11:10 AM

Inpatient Management and Outcomes for HIV-Infected Patients Hospitalized for Acute Coronary Syndromes

**Monica Parks** , Univ of California San Francisco, San Francisco, CA; Eric A Secemsky, Robert W Yeh, Changyu Shen, Eunhee Choi, Dhruv S Kazi, Beth Israel Deaconess Medical Ctr, Boston, MA; Priscilla Hsue, Univ of California San Francisco, San Francisco, CA

11:15 AM

Q & A

# Moderated Digital Posters

## HY.MDP54 - What Is New in Hypertension Research?

#### Moderated Posters 2, Science and Technology Hall

### Monday, November 18, 2019, 10:30 AM - 11:20 AM

10:30 AM

Moderator

Zhenguo Liu, Columbia, MO

10:30 AM

The Ablation of Dendritic Cells Prevents Hypertension by Promoting Natriuresis via NKCC2 in Angiotensin II Treated Mice

**Luis Michea** , Univ de Chile, Santiago, Chile; Patricio A Araos Sr., Univ of Chile, Santiago, Chile; Rodrigo Alzamora, Univ de Chile, Santiago

10:35 AM

Q & A

10:40 AM

Sympathetic Down-Regulation With Etamicastat Ameliorates High Blood Pressure in a Model of Drug-Resistant Hypertension

Bruno Igreja, Nuno Pires, Maria-Joao Bonifacio, Bial, Portela and Cia, Coronado, Portugal; **Patricio Soares-da-Silva** , BIAL, S. Mamede do Coronado, Portugal

10:45 AM

Q & A

10:50 AM

Heterozygous Deletion of Transferrin Receptor 1 Attenuates Renal Fibrosis via Reduction of Oxidative Stress in Mice

**Yoshiro Naito** , Seiki Yasumura, Keisuke Okuno, Masanori Asakura, Masaharu Ishihara, Hyogo Coll Of Med, Nishinomiya, Japan

10:55 AM

Q & A

11:00 AM

The Oxidation of Cyclic GMP-dependent Protein Kinase-1a Induced Salt Sensitive Hypertension Through Activated Sympathetic Nervous System

**Nobuyuki Tokunaga** , Taishi Nakamura, Kumamoto Univ, Kumamoto, Japan; Shokei Kim Mitsuyama, Kenichi Tsujita, Kumamota Univerisity, Kumamoto, Japan

11:05 AM

Q & A

11:10 AM

Acute Antihypertensive Action of NPA7, Innovative Bispecific Designer Peptide, in Spontaneously Hypertensive Rats

Nina A. Dzhoyashvili, Seetha R. Iyer, Mayo Clinic, Rochester, MN; **John C Burnett** , Mayo Clinic Fndn, Rochester, MN

11:15 AM

Q & A

# Abstract Oral Session

## PH.AOS.476 - Kenneth D. Bloch Memorial Lecture in Vascular Biology

#### 102AB

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Mark T Gladwin, Pittsburgh, PA

10:45 AM

Moderator

Jane A Leopold, Boston, MA

10:45 AM

Kenneth D. Bloch Memorial Lecture in Vascular Biology

Evangelos D Michelakis, Edmonton, AB, Canada

11:10 AM

Q & A

11:15 AM

Cardiopulmonary Best Abstract Award: **Small Extracellular Vesicles From LAM-derived Smooth Muscle Cells Contribute to the Destruction of Lung Progenitors**

**Miriel Ho** , Mirabelle S.H. Ho, Lisa Julian, William L Stanford, Duncan J Stewart, Ottawa Hosp Res Inst, Ottawa, ON, Canada

11:25 AM

Q&A

11:30 AM

Role Of PKM2 and Oxidative DNA Damage in the Pathogenesis of Right Ventricular Failure Associated With Pulmonary Arterial Hypertension

**Tsukasa Shimauchi** , Laval Univ, Quebec, QC, Canada; Junichi Omura, Laval university, Quebec, QC, Canada; Sandra Breuils Bonnet, Laval Univ, Quebec, QC, Canada; Roxane Paulin, Laval university, Quebec, QC, Canada; Steeve Provencher, Laval Univ, Quebec, QC, Canada; Olivier Boucherat, Sebastien Bonnet, Laval university, Quebec, QC, Canada

11:40 AM

Q&A

11:45 AM

Distinct Types of Plexiform Lesions in Pulmonary Arterial Hypertension Identified by Synchrotron-Based Phase Contrast Micro-CT

Christian Westöö, Christian Norvik, Niccolò Peruzzi, Lund Univ, Lund, Sweden; Goran Lovric, Paul Scherrer Inst, Villigen, Sweden; Oscar van der Have, Ida Jeremiasen, Rajmund Mokso, Lund Univ, Lund, Sweden; Vinicio A De Jesus Perez, Stanford Univ, Palo Alto, CA; Hans Brunnström, Martin Bech, Lund Univ, Lund, Sweden; Csaba Galambos, Children's Hosp Colorado, Aurora, CO; **Karin Tran-Lundmark** , Lund Univ, Lund, Sweden

11:55 AM

Q&A

# Abstract Oral Session

## AT.AOS.465 - Sol Sherry Distinguished Lecture in Thrombosis

#### 126B

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Marvin T Nieman, Cleveland, OH

10:45 AM

Moderator

Gissette Reyes-soffer, New York, NY

10:45 AM

Sol Sherry Distinguished Lecture in Thrombosis

Katherine A High, Philadelphia, PA

11:10 AM

Q&A

11:15 AM

Polo-Like Kinase 3, a Mitotic Kinase is a Novel Regulator of Thrombosis

**Meghna U Naik** , Brendan U Bachman, Ulhas P Naik, Thomas Jefferson Univ, Philadelphia, PA

11:25 AM

Q & A

11:30 AM

Homeostasis vs. Hemostasis: The Role of Platelets in Maintaining Vascular Barrier Function in the Absence of Injury

**Shuchi Gupta** , Lawrence F Brass, Univ of Pennsylvania, Philadelphia, PA

11:40 AM

Q & A

11:45 AM

Transcriptomic Profiling of Reticulated Platelets

**Dario Bongiovanni** , Klinikum recht der Isar, Munich, Germany; Donato Santovito, LMU Munich, Munich, Germany; Gianluca Santamaria, Klinikum recht der Isar, Munich, Germany; Christian Weber, LMU Munich, Munich, Germany; Gianluigi Condorelli, Humanitas Res Hosp, Milan, Germany; Karl-Ludwig Laugwitz, Isabell Bernlochner, Klinikum recht der Isar, Munich, Germany

11:55 AM

Q & A

# Cardiovascular Seminar

## NR.CVS.126 - Applying Life's Simple 7 When Life Is NOT SIMPLE

#### 113A

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Lola Coke, Chicago, IL

10:45 AM

Moderator

Willie Mae Abel, Charlotte, NC

10:45 AM

The Life's Simple 7 and Prevalence of Ideal Cardiovascular Health Among Minorities

Gayenell Magwood, Charleston, SC

10:57 AM

"Corazón de la Familia" ("Heart of the Family"): A Family Dyad Intervention Guided by the Life's Simple 7

Gia Mudd-Martin, Lexington, KY

11:09 AM

Feasibility and Acceptability of a Life's Simple 7 mHealth Intervention to Reduce Cardiovascular Disease Risk

LaPrincess Brewer, Rochester, MN

11:21 AM

Peer Support Group Intervention to Reduce Risks of Heart Disease and Stroke Among African American Men According to Life's Simple 7

Sohye Lee, Memphis, TN

11:33 AM

Adversity, Life's Simple 7 and Cardiovascular Disease

Michelle A Albert, San Francisco, CA

11:45 AM

Using the Life's Simple 7 to Reduce Stroke Risk in Young Adult African Americans

Dawn Aycock, Atlanta, GA

11:57 AM

Discussion

# Cardiovascular Seminar

## CA.CVS.17 - Cardiac Morphogenesis and Implications in Congenital Heart Disease

#### 119AB

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Kathy O Lui, Hong Kong

10:45 AM

Moderator

James Priest, Stanford, CA

10:45 AM

Hand1 Impacts LV Conduction System Morphogenesis & Function

Anthony Firulli, Indianapolis, IN

10:55 AM

Q & A

11:00 AM

Hypoplastic Left Heart Syndrome

Cecilia Lo, Pittsburgh, PA

11:10 AM

Q & A

11:15 AM

Mechanism of Trabecular Formation

Mingfu Wu, Albany, NY

11:25 AM

Q & A

11:30 AM

Mechanism of Human Atrial Development

Stephanie Protze, Toronto, Canada

11:40 AM

Q & A

11:45 AM

Heart Field Lineage Specification

Chulan Kwon, Baltimore, MD

11:55 AM

Q & A

# Cardiovascular Seminar

## IM.CVS.366 - Cardiovascular Imaging in Athletes

#### 108B

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Alan Matsumoto, Charlottesville, VA

10:45 AM

Moderator

Dominik Fleischmann, Stanford, CA

10:45 AM

Strong Hearts: Cardiac MRI in Athletes

Anil Attili, MI

11:00 AM

Fast Hands: Vascular Lesions of the Upper Extremity

Richard L. Hallett, Stanford, CA

11:10 AM

Flexible Hips: Imaging of Iliac Endofibrosis

Patrick T NORTON, Charlottesvle, VA

11:20 AM

Bulky Calves: Popliteal Entrapment

Benoit Desjardins, Philadelphia, PA

11:30 AM

Release and Debulking: Sugical Management

Jason Lee, Stanford, CA

11:45 AM

Panel Discussion

# Cardiovascular Seminar

## SI.CVS.181 - Emerging Roles for Protein Phosphatases in Cardiac Physiology and Disease

#### 120B

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Rongxue Wu, Chicago, IL

10:45 AM

Moderator

Maike Krenz, Columbia, MO

10:45 AM

The Therapeutic Potential of Cardiac Protein Phosphatases

Coralie Poizat, San Diego, CA

10:55 AM

Q&A

11:00 AM

Targeting Dual-Specificity Phosphatases (DUSPs) in Cardiac Remodeling and Failure

Riujie Liu, Allendale, MI

11:10 AM

Q&A

11:15 AM

Protein Phosphatases in Arrhythmogenesis and Atrial Fibrillation

Ali El-Armouche, Erlangen, Germany

11:25 AM

Q&A

11:30 AM

Role of PHLPP in Cardiac Growth and Survival

Nicole H Purcell, La Jolla, CA

11:40 AM

Q&A

11:45 AM

Beta-adrenergic Regulation of Cardiac Protein Phosphatases

Kate L Weeks, Melbourne, Australia

11:55 AM

Q&A

# Cardiovascular Seminar

## MP.CVS.138 - Epigenetic Regulation of Cardiovascular Disease

#### 120C

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Matt Stratton, Columbus, OH

10:45 AM

Moderator

Donald R Menick, Charleston, SC

10:45 AM

RNA Methylation in Cardiac Hypertrophy

Federica Accornero, Columbus

10:55 AM

Q&A

11:00 AM

Histone Methylation in Heart Failure

Sarah Franklin, Salt Lake City, UT

11:10 AM

Q&A

11:15 AM

Chromatin Architecture in Heart Failure

Tom M Vondriska, Los Angeles, CA

11:25 AM

Q&A

11:30 AM

HDACs, Epigenetics and Heart Failure

Johannes Backs, Heidelberg, Germany

11:40 AM

Q&A

11:45 AM

HDAC Inhibitors for the Treatment of HFpEF

Timothy McKinsey, Aurora, CO

11:55 AM

Q&A

# Cardiovascular Seminar

## GE.CVS.245 - Genome-Environment Regulation in Congenital Heart Defects

#### 121C

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Marlin Touma, Los Angeles, CA

10:45 AM

Moderator

Todd Evans, New York, NY

10:45 AM

Gene-Environment Regulatory Circuits in Neonatal Heart Chamber Development and Congenital Heart Defects

Marlin Touma, California, CA

11:00 AM

Genetics and Genomics of Congenital Heart Defects: New Frontiers

Bruce Gelb, Mount Sinai, NY

11:15 AM

Genomic Architecture of Adverse Right Ventricular Remodeling in Teralogy of Fallot

Seema Mital, Toronto, Canada

11:30 AM

New Functional Genomics Approaches for Precision Cardiovascular Research

William Pu, Boston, MA

11:45 AM

Panel Discussion

# Cardiovascular Seminar

## HY.CVS.500 - Guideline-Based Strategies for Improving Control of High Blood Pressure: The 2019 ACC/AHA Performance and Quality Measures for Adults with High Blood Pressure

#### 204C

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Donald E Casey Jr., Chicago, IL

10:45 AM

How should we manage High BP: Overview of Performance Measures

Donald E Casey Jr., Chicago, IL

11:00 AM

How should we manage High BP: Overview of Quality Measures

Gregory Wozniak, Chicago, IL

11:15 AM

What Systems Approaches are Most Effective: Overview of Structural Quality Measures.

Yvonne Commodore-mensah, Baltimore, MD

11:30 AM

Q & A with Panel Discussion

# Cardiovascular Seminar

## AT.CVS.424 - Novel Insights of Vascular Smooth Muscle Cells in Cardiovascular Diseases

#### 126A

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Eugene Chen, Ann Arbor, MI

10:45 AM

Moderator

Mark W Majesky, Seattle, WA

10:45 AM

Regulation of SMC Function and Neointima Formation

Mary C Weiser-Evans, Denver, CO

10:55 AM

Q&A

11:00 AM

SMC TGF-ß Signaling and Fibrosis

Kathleen A Martin, New Haven, CT

11:10 AM

Q&A

11:15 AM

Hippo-YAP Pathway in SMC Phenotypic Modulation

Jiliang Zhou, Augusta, GA

11:25 AM

Q&A

11:30 AM

SMC Single Cell Transcriptome and Vascular Diseases

Helle F Jørgensen

11:40 AM

Q&A

11:45 AM

SMC in Vascular Development and Disease

Brenda Lilly, Columbus, OH

11:55 AM

Q&A

# Cardiovascular Seminar

## VA.CVS.502 - PVD Workshop: Skeletal Muscle Pathology and Regeneration in PAD

#### 103B

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Panagiotis Koutakis, Tallahassee, FL

10:45 AM

Moderator

Ngan F Huang, Stanford, CA

10:45 AM

Ischemia Reperfusion Injury and Muscle Regeneration in PAD Patients

Panagiotis Koutakis, Tallahassee, FL

11:00 AM

Biomaterials-based MSC for Treatment of Murine Hindlimb Ischemia

Ngan F Huang, Stanford, CA

11:15 AM

Pathological Changes in Calf Muscle Associated with Standard Exercise Treadmill Therapy Suggest the Need to Reevaluate the form of Exercise Therapy for Claudicating Patients

Iraklis I Pipinos, Omaha, NE

11:30 AM

Interventions Targeting Muscle Pathology in PAD

Mary M McDermott, Chicago, IL

11:45 AM

Discussion

# Cardiovascular Seminar

## HY.CVS.110 - Stem Cells, Exosomes and Hypertension

#### 108A

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Guo-Chang Fan, Cincinnati, OH

10:45 AM

Moderator

Young S Oh

10:45 AM

Renal Stem Cells and Salt-Sensitive Hypertension

Ningjun Li, Richmond, VA

11:00 AM

Transplant of Bone Marrow Cells From miR-150 KnockOut Mice Enhances Immune Function and Attenuates Arterial Stiffness and Hypertension in SAMP1 Mice

Zhongjie SUN, Memphis, TN

11:15 AM

Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuate Kideny Inflammation

Lilach O Lerman, Rochester, MN

11:30 AM

Plasma Exosomes Regulate Systemic Blood Pressure

Hideyuki Yamawaki, Towada, Japan

11:45 AM

Discussion

# Cardiovascular Seminar

## IN.CVS.433 - Updates in Interventional Therapies for Non-Cardiac Vascular Disease

#### 107AB

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Subhash Banerjee, Dallas, TX

10:45 AM

Moderator

Parag J PATEL, Milwaukee, WI

10:45 AM

Panel Participant

Manu Kaushik, Omaha, NE

10:45 AM

Panel Participant

Christopher J White, New Orleans, LA

10:45 AM

Panel Participant

Mehdi H Shishehbor, Cleveland, OH

10:45 AM

Renal Denervation, Where are We Now, and What are Waiting for?

Felix Mahfoud, Homburg/Saar, Germany

11:00 AM

Panel Discussion

11:04 AM

Drug Eluting Balloon and Stents, Promise and Caution

Mehdi H Shishehbor, Cleveland, OH

11:19 AM

Panel Discussion

11:38 AM

Panel Discussion

11:42 AM

Stroke Prevention, What is the Role of Carotid Stenting?

Christopher White, New Orleans, LA

11:56 AM

Panel Discussion

# Main Event

## LF.ME.525 - As the World Turns Hotter: CV Emergency or Opportunity?

#### Main Event I

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Jennifer G ROBINSON, Iowa City, IA

10:45 AM

Moderator

Mahdi GARELNABI, Lowell, MA

10:55 AM

Adverse Health Effects of Climate Change

John Balbus

11:25 AM

What HealthCare Professionals Can Do

Caren Solomon, MA

11:35 AM

Panel Discussion

11:47 AM

Audience Discussion

# Main Event

## CO.ME.333 - Cardio-Oncology or Onco-Cardiology: Cardiac and Cancer Treatment in the Balance

#### Main Event II

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Moderator

Geoffrey D. Rubin, Durham, NC

10:45 AM

Moderator

Mario J Garcia, Bronx, NY

10:45 AM

Cardiotoxic Effects of Chemotherapeutic Agents and Immune Modulators

Edward Yeh, Columbia, MO

10:57 AM

Functional and Structural Characterization of Cardiotoxicity

Marielle Scherrer-Crosbie, Boston, MA

11:21 AM

Cancer, Chemotherapy and Thromboembolism

Nigel Mackman, Chapel Hill, NC

11:33 AM

Imaging Vascular Events in the Cancer Patient

Daniel Ocazionez, Houston, TX

11:57 AM

Discussion

# Main Event

## QU.ME.600 - Highlights of the Value in Healthcare Initiative – Implications for Cardiovascular Science and Practice

#### Nutter Theatre

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

Nancy Brown - Moderator

10:45 AM

**Nancy Brown - Speaker -** Setting the Stage

10:55 AM

**Panel 1:** Reimagining Clinical Trials

10:55 AM

Panel 1 Facilitator

Robert McKinnon Califf, Durham, NC

10:55 AM

**Panel** 1 **Participant**

Stephanie Austin, TX

10:55 AM

**Panel** 1 **Participant**

Stephen Friedhoff, IN

10:55 AM

**Panel** 1 **Participant**

Ricardo Rocha, East Hanover, NJ

10:55 AM

**Panel** 1 **Participant**

John J Warner, Dallas, TX

11:25 AM

Panelists Switch

11:30 AM

**Panel 2:** System Readiness for Value-Based Models

11:30 AM

Panel 2 Facilitator

Mark McClellan, NC

11:30 AM

**Panel** 2 **Participant**

Arnaud Bernaert, Cologny, Switzerland

11:30 AM

**Panel** 2 **Participant**

Mary Leah Coco, Baton Rouge, LA

11:30 AM

**Panel** 2 **Participant**

Steven Farmer, Washington, DC

11:30 AM

**Panel** 2 **Participant**

Karen E Joynt Maddox, Saint Louis, MO

11:30 AM

**Panel** 2 **Participant**

Christopher O Connor, Falls Church, VA

# Meet the Trialists

## CS.MT.06 - Meet the Trialists ORION Trials

#### Game Central

### Monday, November 18, 2019, 10:45 AM - 12:00 PM

10:45 AM

ORION - 9

Frederick Johan Raal, Johannesburg, South Africa

10:45 AM

ORION - 10

R Scott S Wright, Rochester, MN

# Abstract Poster Session

## AC.APS.10 - Acute Coronary Syndromes: Plunging the Depths of Pathobiology

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 4032

Temporal Trend and Distribution of Advanced Atherosclerotic Plaque Morphology Among Patients With Acute Coronary Syndrome

Fahimehalsadat Shojaei, Beth Israel Deaconess Med Ctr, Boston, MA; Yuyin Liu, Baim Inst for Clinical Res, Boston, MA; Homa Najafi, Sogand Goudarzi, Sahar Memar Montazerin, Sadaf Sharfaei, Beth Israel Deaconess Med Ctr, Boston, MA; Farbod Zahedi Tajrishi, Babol Univ of Medical Sciences, Babol, Iran, Islamic Republic of; Sara Mehrsefat, Univ of Central Florida, Kissimmee, FL; Adeel Jamil, OSF Saint Francis Medical Ctr, Peoria, IL; Jolanta Marszalek, Univ of Arkansas for Medical Sciences, Little Rock, AR; Jane Lee, Baim Inst for Clinical Res, Boston, MA; **Gerald Chi** , Beth Israel Deaconess Med Ctr, Boston, MA

11:30 AM

Board # 4033

Plaque Rupture Observed by Optical Coherence Tomography is Associated With the Progression of Carotid Atherosclerosis in Patients With Acute Myocardial Infarction

**Masahiro Yamada** , Hirosaki Univ Graduate Sch of Med, Hirosaki, Japan; Fumie Nishizaki, Kenji Hanada, Hirosaki Univ, Hirosaki, Japan; Tomohide Endo, Hirosaki Univ Graduate Sch of Med, Hirosaki, Japan; Hiroaki Yokoyama, Hirosaki Univ Graduate Sch, Hirosaki, Japan; Takashi Yokota, Hirosaki Univ Graduate Sch of Med, Hirosaki, Japan

11:30 AM

Board # 4034

The Clinical Significance of Aspirated Atheroma and Cholesterol Crystal in ST Elevation Myocardial Infarction

**Takashi Nakamura** , Yoshitaka Iwanaga, Takayuki Kawamura, Heitaro Watanabe, Masakazu Yasuda, Kenji Yamaji, Masafumi Ueno, Takashi Kurita, Kinki Univ, Osakasayama, Japan

11:30 AM

Board # 4035

Circadian Dependence of Microvascular Obstruction in ST-elevation Myocardial Infarction

Nicole Bonfig, Minneapolis Heart Inst Fndn and Univ of Minnesota, Minneapolis, MN; Sarah J Davidson, Ross F Garberich, Minneapolis Heart Inst Fndn at Abbott NW Hosp, Minneapolis, MN; Timothy D Henry, The Christ Hosp, Cincinnati, OH; **Jay H Traverse** , Minneapolis Heart Inst Fndn and Univ of Minnesota, Minneapolis, MN

11:30 AM

Board # 4036

The Impact of Arterial Stiffness Assessed by Cardio-ankle Vascular Index on Long-term Outcome in Patients With Acute Coronary Syndrome

**Jin Kirigaya** , Noriaki Iwahashi, Yokohama City Univ Medical Ctr, Yokohama, Japan; Masaomi Gohbara, Nanbu Hosp, Yokohama, Japan; Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Yokohama City Univ Medical Ctr, Yokohama, Japan; Kouichi Tamura, Yokohama City Univ Graduate Sch of Med, Yokohama, Japan; Kazuo Kimura, Yokohama City Univ Medical Ctr, Yokohama, Japan

11:30 AM

Board # 4037

Cancer and Mechanisms of Myocardial Infarction in Women

Priya Panday, NYU Sch of Med, New York, NY; **Anais Hausvater** , NYU Langone Medical Ctr, New York, NY; Nathaniel Smilowitz, NYU Sch of Med, New York, NY; Thara Ali, NYU Langone Health, New York, NY; Rediet Mersha, NYU Sch of Med, New York, NY; Harmony Reynolds, NYU Sch Med, New York, NY

11:30 AM

Board # 4038

Oncologic Patients Presenting Acute Coronary Syndromes Have High Atherosclerotic Burden, Complex Anatomical Plaques and Particular Plaque Rupture Distribution

**Vinicius B Seleme** , Carlos Campos, Heart Inst, Sao Paulo, Brazil; Isabela Bispo, Cancer Inst, Sao Paulo, Brazil; Diego C Borges, Heart Inst, Sao Paulo, Brazil; Cristina S Bittar, Silva Carolina, Silvia Fonseca, Giovani H Pinto, Cancer Inst, Sao Paulo, Brazil; Expedito E. Ribeiro, Incor, Sao Paulo, Brazil; Roberto Kalil Filho, Heart Inst, Sao Paulo, Brazil; Ludhmila Hajjar, Heart Inst, SAO PAULO, Brazil

11:30 AM

Board # 4040

Incidence of Acute Myocardial Infarction and Hurricane Katrina: Twelve Years After the Storm

**Asaad Nakhle** , Bradley Deere, Michael Razavi, Sudesh K Srivastav, Tulane Univ, New Orleans, LA; Harsh Rawal, Advocate Illinois Masonic Hosp, Chicago, IL; Daniel Harrison, Anand M Irimpen, Tulane Univ, New Orleans, LA

11:30 AM

Poster Professor

Renu Virmani, Gaithersburg, MD

# Abstract Poster Session

## AT.APS.16 - Adipose Tissues and Vascular Function

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 1000

CTRP1 Promotes Vasodilatory Dysfunction by Increasing Nitric Oxide Synthase Dysfunction Through Adipo-Vascular Axis

**Xiao Qun Wang** , Zhu Hui Liu, Jia Wei Chen, Chang Li, Xin Yi Shu, Ying Shen, Rui Yan Zhang, Wei Feng Shen, Lin Lu, Ruijin Hosp, Shanghai Jiao-Tong Univ Sch of Med, Shanghai, China

11:30 AM

Board # 1001

Interleukin-19 is a Novel Immunoregulatory, Pro-Angiogenic Adipokine

**Christine Vrakas** , Allison Herman, Sheri E Kelemen, Rosario G Scalia, Michael Autieri, Temple Univ, Philadelphia, PA

11:30 AM

Board # 1002

Vascular Modulation of Adipose Function: Role of Endothelial Argonaute 1

Xiaofang Tang, City of Hope, Duarte, CA; Yifei Miao, Stanford Sch of Med, Stanford, CA; Zhijie Qi, Univ of California San Diego, La Jolla, CA; Kendall Van Keuren-Jensen, Translational Genomics Res Inst, Pheonix, AZ; Gene Yeo, Univ of California San Diego, La Jolla, CA; Rama Natarajan, Beckman Res Instit of City of Hope, Duarte, CA; Sheng Zhong, Univ of California San Diego, La Jolla, CA; **Zhen Chen** , City of Hope, Duarte, CA

11:30 AM

Board # 1003

The Relationship Among Local Epicardial Adipose Tissue, Coronary Intraplaque Microluminal Structure, and Coronary Plaque Formation -A Fresh Cadaveric Study-

**Yutaka Kawabata** , Tokushima Univ Hosp, tokusima, Japan; Tetsuzo Wakatsuki, Koji Yamaguchi, Tokushima Univ Hosp, Tokushima, Japan; Hiroyuki Ito, Tomomi Matsuura, Tokushima Univ Hosp, tokusima, Japan; Takayuki Ise, Kenya Kusunose, Tokushima Univ Hosp, Tokushima, Japan; Takeshi Tobiume, Tokushima Univ Hosp, Tokushima-ken, Japan; Shusuke Yagi, Univ of Rochester, Tokushima, Japan; Hirotsugu Yamada, Tokushima Univ Hosp, Naruto, Japan; Daiju Fukuda, Takeshi Soeki, Tokushima Univ, Tokushima, Japan; Masataka Sata, Tokushima Univ Graduate Sch, Tokushima, Japan

11:30 AM

Board # 1004

Implantation of Adipose-Derived Regenerative Cells Promotes Coordinated Angiogenesis and Lymphangiogenesis in Reparative Hind Limb Ischemia Model

**Zhongyue Pu** , Yuuki Shimizu, Kazuhito Tsuzuki, Junya Suzuki, Toyoaki Murohara, Nagoya Univ, Nagoya, Japan

11:30 AM

Board # 1005

**Human CD271** + **Adipose-Derived Stem Cells are the Angiogenic Subset With MTOR Expression and Long-Term Engraftment Capacity**

**Oto Inoue** , Kanazawa Univ, Kanazawa, Japan; Soichiro Usui, Univ Kanazawa, Kanazawa, Japan; Kosei Yamaguchi, Yusuke Takeda, Ayano Nomura, Kanazawa Univ, Kanazawa, Japan; Takuto Hamaoka, Kanazawa Univ Hosp, Kanazawa, Japan; Chiaki Goten, Kanazawa Univ, Kanazawa, Japan; Shin-ichiro Takashima, Kanazawa Univ Hosp, Kanazawa, Japan; Hiroshi Ootsuji, Kenji Iino, Hisayoshi Murai, Kenji Sakata, Masa-aki Kawashiri, Hirofumi Takemura, Masayuki Takamura, Kanazawa Univ, Kanazawa, Japan

11:30 AM

Board # 1006

Pathophysiological Role of Browning of Perivascular Adipose Tissue in the Development of Vascular Remodeling

**Yusuke Adachi** , Kazutaka Ueda, The Univ of Tokyo, Tokyo, Japan; Kaoru Ito, Riken Ctr for Integrative Medical Sciences, Kanagawa, Japan; Eiki Takimoto, Issei Komuro, The Univ of Tokyo, Tokyo, Japan

11:30 AM

Board # 1007

**Human CD271** + **Adipose-Derived Stem Cells Possess Angiogenic Capacity Through Mediating M2-Dominant Macrophage Polarization in Cell Therapy**

**Kosei Yamaguchi** , Oto Inoue, Yusuke Takeda, Chiaki Goten, Shinichiro Takashima, Kanazawa Univ, Kanazawa, Japan; Soichiro Usui, Univ Kanazawa, Kanazawa, Japan; Kenji Sakata, Masa-aki Kawashiri, Masayuki Takamura, Kanazawa Univ, Kanazawa, Japan

11:30 AM

Board # 1008

Circulating Mature Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Level Predicts Diminished Response to Statin Therapy in Patients With Coronary Artery Disease

**Kuyama Naoto** , Mariko Harada-Shiba, Mika Hori, Masatsune Ogura, Yasuhide Asaumi, Teruo Noguchi, Satoshi Yasuda, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Yu Kataoka, Natl Cardiovascular Ctr, Suita, Japan

11:30 AM

Board # 1009

Meta- Analysis of Lowering Apolipoprotein B With Mortality and Cardiovascular Outcomes Across Various Lipid Lowering Therapies

**Safi Ullah Khan** , West Virginia Univ, Morgantown, WV; Muhammad Usman Khan, West Virginia Univ, HSC, Morgantown, WV; Shahul Valavoor, West Virginia Univ, Morgantown, WV; Muhammad Shahzeb Khan, John H. Stroger J. Hosp of Cook County, Chicago, IL; Victor Okunrintemi, East Carolina Univ, Greenville, NC; Mamas Andreas Mamas, Univ of Keele, Keele, United Kingdom; Thorsten M. Leuker, Johns Hopkins Sch of Med, Baltimore, MD; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD

# Abstract Poster Session

## EP.APS.28 - Cancer: Surveillance, Trends and Outcomes

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 3051

Cancer Survivorship and Incident Cardiovascular Events in the Aric Study

**Roberta Florido** , Johns Hopkins Univ, Baltimore, MD; Natalie Rula Daya, Johns Hopkins, Baltimore, MD; Silvia Koton, Tel Aviv Univ, Tel Aviv, Israel; Chiadi Ericson Ndumele, Johns Hopkins Univ, Baltimore, MD; Stuart D Russell, Duke Univ Medical Ctr, Raleigh, NC; Roger S Blumenthal, Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD; Ye Jin Mok, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Ashley Felix, The Ohio State Univ, Columbus, OH; Morgan Grams, Johns Hopkins Univ, Baltimore, MD; Josef Coresh, Johns Hopkins SPH Welch Ctr, Baltimore, MD; Corinne E. Joshu, Elizabeth A. Platz, Johns Hopkins Sch of Public Health, Baltimore, MD; Elizabeth Selvin, Johns Hopkins Univ, Baltimore, MD

11:30 AM

Board # 3052

Healthcare Utilization and Hospital Variation of Cardiac Surveillance During Breast Cancer Treatment

**Yvonne Koop** , Angela H.E.M. Maas, Saloua El Messaoudi, Hester Vermeulen, Femke Atsma, Radboudumc, Nijmegen, Netherlands

11:30 AM

Board # 3053

Prevalence And Impact Of Atrial Fibrillation In Hospitalized Solid Organ Cancer Patients

**Srikanth Yandrapalli** , Westchester Medical Ctr, White Plains, NY; Aaqib Malik, Glory Atuh, Westchester Medical Ctr, Valhalla, NY; Gayatri Pemmasani, Guntur Medical Coll, Guntur, India; Gowthami Kobbari, Westchester Medical Ctr, Valhalla, NY; Wilbert S Aronow, New York Medical Coll, New Rochelle, NY; Howard A Cooper, Julio A Panza, Diwakar Jain, Westchester Medical Ctr, Valhalla, NY

11:30 AM

Board # 3054

Myocardial Infarction in Patients With Concomitant Cancer

**Fangcheng Wu** , Memorial Hosp West, Pembroke Pines, FL; Pengyang Li, Saint Vincent Hosp, Worcester, MA; Kevin Buda, Hennepin County Medical Ctr, Minneapolis, MN; Anand Muthu Krishnan, Univ of Connecticut, Farmington, CT; Anil Jha, Lawrence General Hosp, Lawrence, MA; Ying Ning, Saint Vincent Hosp, Worcester, MA; Kristina X Duan, Baylor Coll of Med, Houston, TX; Qi Liu, Texas Heart Inst, Houston, TX

11:30 AM

Board # 3055

Temporal Association Between Breast Cancer and Heart Failure in Postmenopausal Women

**Phillip H Lam** , Ana Barac, MedStar Heart and Vascular Inst, Washington, DC; Anju Nohria, Brigham and Women's Hosp, Boston, MA; Kerryn Reding, Univ of Washington, Seattle, WA; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; Kathy Pan, Los Angeles Biomedical Res Inst, Torrance, CA; Helen Sheriff, DC VAMC, Washington, DC; Charity Morgan, Univ of Alabama-Birmingham, Birmingham, AL; Samer S Najjar, Medstar Washington Hosp Ctr, Washington, DC; Rowan Chlebowski, UCLA Torrance, Torrance, CA; Liviu Klein, Univ of California, San Francisco, CA; Charles B Eaton, Brown Univ, Pawtucket, RI; Barbara V Howard, Medstar Health and Georgetown U, Bonita Spgs, FL; Ali Ahmed, VA Medical Ctr, Washington, DC; Selma Mohammed, MedStar Heart and Vascular Inst, Washington, DC

11:30 AM

Board # 3056

Predictors of Mortality Among Cancer Patients Treated With Checkpoint Inhibitors

**Ali M Agha** , Natalie Chen, UT Houston, Houston, TX; Christopher Chen, Baylor Coll of Med, Houston, TX; Henry Zheng, BCM, Houston, TX; Jacob Morgan, Abir Khan, Baylor Coll of Med, Houston, TX; Juan Lopez-Mattei, MD Anderson Cancer Ctr, Houston, TX; Rohit Moudgil, Cleveland Clinic, Cleveland, OH; Cezar Iliescu, MD Anderson Cancer Ctr, Houston, TX; Nicolas Lawrence Palaskas, UT MD Anderson Cancer Ctr, Houston, TX

11:30 AM

Board # 3057

Trends in Reported Cardiovascular Disease and Hospitalizations in Cancer Patients - Cardio-oncology Patterns Over 14-year From Two Nationally Representative Datasets

**Avirup Guha** , Case Western Reserve Univ, Cleveland, OH; Amit K. Dey, NHLBI,Natl institutes of Health, Bethesda, MD; Elliott Miller, Yale Univ, New Haven, CT; Michael George Fradley, Univ of South Florida, Tampa, FL; Nihar R. Desai, Yale Sch of Med, New Haven, CT; Daniel Addison, Ohio State Univ, Columbus, OH

11:30 AM

Board # 3058

The Association of Cardiovascular Disease and Future Cancer

**Emily Lau** , Samantha M Paniagua, Elizabeth Liu, Manol Jovani, Shawn Li, Katherine Takvorian, Massachusetts General Hosp, Boston, MA; Vasan S Ramachandran, Greta L Splanksy, Framingham Heart Study, Framingham, MA; Bernard Kreger, Boston Univ Sch of Med, Boston, MA; Martin Larson, Boston Univ, Boston, MA; Daniel Levy, NHLBI-Framingham Heart Study, Framingham, MA; Jennifer E Ho, Massachusetts General Hosp, Newton, MA

11:30 AM

Board # 3059

Impact of Financial Burden Associated With Atrial Fibrillation in Cancer: Insights From National Inpatient Sample

**Avirup Guha** , Case Western Reserve Univ, Cleveland, OH; Amit K. Dey, NHLBI, Natl institutes of Health, Bethesda, MD; Rebecca Carter, The Ohio State Univ, Columbus, OH; Daniel Addison, Ohio State Univ, Columbus, OH; Michael George Fradley, Univ of South Florida, Tampa, FL

11:30 AM

Board # 3060

Is HEART Score Adequate for Triaging Acute Chest Pain in Cancer Survivors?

**Ahmad Mahmoud** , Hongjin Li, Omar Abu-Jaradeh, Ziad Faramand, Stephanie O Frisch, Christian Martin-Gill, Univ of Pittsburgh, Pittsburgh, PA; Clifton W Callaway, Univ Pittsburgh, Pittsburgh, PA; Salah S Al-Zaiti, Univ of Pittsburgh, Pittsburgh, PA

# Abstract Poster Session

## EA.APS.26 - Cardiac Arrhythmia - Valvular Heart Disease/Risk Factors

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2030

Suspected Arrhythmogenic Bileaflet Mitral Valve Prolapse Syndrome in the Absence of Sudden Cardiac Death: A Single Center Experience

**John Giudicessi** , Peter Alexander Noseworthy, Michael John Ackerman, Mayo Clinic, Rochester, MN

11:30 AM

Board # 2031

Machine Learning Helps Predict Permanent Pacemaker Requirement Post Transcatheter Aortic Valve Replacement

**Pradyumna Agasthi** , Farouk Mookadam, Mayo Clinic, Scottsdale, AZ; Nithin Venepally, Mayo Clinic, Phoenix, AZ; Marlene Girardo, Matthew Buras, Banveet K Khetarpal, Mayo Clinic, Scottsdale, AZ; Siva K Mulpuru, Mackram Eleid, Kevin Greason, Mayo Clinic, Rochester, MN; Nirat Beohar, Columbia Univ Div, Miami Beach, FL; John Sweeney, Mayo Clinic, Scottsdale, AZ; F David Fortuin Jr., Mayo Clinic, Phoenix, AZ; David R Holmes, Mayo Clinic, Rochester, MN; Reza Arsanjani, Mayo Clinic, Scottsdale, AZ

11:30 AM

Board # 2032

Junctional Rhythm Following Transcatheter Aortic Valve Replacement

**Natthapon Angsubhakorn** , Baris Akdemir, Stefan C Bertog, Minneapolis VA Health Care System, Minneapolis, MN; Santiago Garcia, Minneapolis Heart Inst, Edina, MN; Wasawat Vutthikraivit, Texas Tech Health Sciences Ctr, Lubbock, TX; Selcuk Adabag, Minneapolis VA Health Care System, Minneapolis, MN

11:30 AM

Board # 2033

Characterization of Myocardial Inflammation and Fibrosis in Patients With Arrhythmic Mitral Valve Prolapse and Only Mild or Moderate Mitral Regurgitation

**Adam J Russak** , Maria G Trivieri, Jalaj Garg, Philip M Robson, Amit Pawale, Renata Pyzik, Steve L Liao, Ahmed El-Eshmawi, Percy Boateng, Dimosthenis Pandis, Srinivas R Dukkipati, Vivek Y Reddy, David H Adams, Zahi A Fayad, Marc A Miller, Icahn Sch of Med at Mount Sinai, New York, NY

11:30 AM

Poster Professor

Jennifer N Avari Silva, Saint Louis, MO

11:30 AM

Board # 2034

Increased Blood Pressure Was Associated With Prolonged Electrocardiographic Tpeak-Tend Interval in a General Chinese Population

**Tingting Lv** , Tsinghua Univ, Beijing, China; Yifang Yuan, Beijing Tsinghua Changgung Hosp, Beijing, China; Huijuan Li, Peking Univ, Beijing, China; Jing Yang, Lingyun Kong, Beijing Tsinghua Changgung Hosp, Beijing, China; Jiayu Wang, Peking Univ People's Hosp, Beijing, China; Zhaoguo Zhang, Beijing Sijiqing Hosp, Beijing, China; Xingjie Li, Jining No. 1 People's Hosp, Beijing, China; Yingxian Sun, First Affiliated Hosp of China Medical Univ, Shenyang, China; Xuewen Li, Shanxi Acad of medical sciences, Shanxi Dayi Hosp, Taiyuan, China; Zheng Zhang, First Hosp Affiliated to Lanzhou Univ, Lanzhou, China; Xiaoshu Cheng, Second Affiliated Hosp of Nanchang Univ, Nanchang, China; Lirong Wu, Affiliated Hosp of Guiyang Medical Coll, Guiyang, China; Xuerui Tan, The First Affiliated Hosp of Shantou Univ Medical Coll, Shantou, China; Bing Han, Xuzhou Central Hosp, Xuzhou, China; Yanfang Wang, Peking Univ, Beijing, China; Hua Li, Beijing Tsinghua Changgung Hosp, Beijing, China; Yangfeng Wu, Peking Univ, Beijing, China; Jihong Guo, Peking Univ People's Hosp, Beijing, China; Ping Zhang, Beijing Tsinghua Changgung Hosp, Beijing, China

11:30 AM

Board # 2035

The Prognostic Impact of Ventricular Tachycardia and Fibrillation in Patients Presenting With Stemi

Mahmoud Abdelnabi, Abdallah Almaghraby, Alexandria Univ, Alexandria, Egypt; **Yehia Saleh** , Michigan Sate Univ, East Lansing, MI; Ola Abdelkarim, Alexandria Univ, Alexandria, Egypt; Khader Herzallah, Michigan State Univ, East Lansing, MI; Tuğba Öz, Medipol Üniversitesi Çamlıca Hastanesi, Istanbul, Turkey; Layan El-khatib, Michigan State Univ, East Lansing, MI; Haitham Badran, Ain Shams Univ, Cairo, Egypt

11:30 AM

Board # 2036

Difference in QTc Prolongation During Obstructive Apneas versus Hypopneas

**Dana Vondrova** , Univ of Southern California, Manhattan Beach, CA; Hussain Basrawala, LAC USC Medical Ctr, Los Angeles, CA; Pavan Reddy, Los Angeles County USC, Los Angeles, CA; Edwin Valladares, Univ of Southern California, Los Angeles, CA; Krishan Patel, USC, Los Angeles, CA; Shamili Allam, LAC USC Medical Ctr, Los Angeles, CA; Jan Konecny, Masaryk Univ, Brno, Czech Republic; Michael C Khoo, Univ Southern Calif, Arcadia, CA; Rahul N Doshi, Univ of Southern California, Henderson, NV; Vincent X Grbach, Univ of Southern California, San Antonio, TX; Terese Hammond, Keck of USC, Pasadena, CA; Zea Borok, Univ of Southern California, Los Angeles, CA; Richard James Castriotta, Univ of Southern California, Houston, TX; Tomas Konecny, Univ of Southern California, Los Angeles, CA

11:30 AM

Board # 2037

Association of Life's Simple 7 Score With Premature Atrial Contractions Frequency: The Atherosclerosis Risk in Communities Study

**Darshan Krishnappa** , Univ of Minnesota, Minneapolis, MN; Wendy Wang, Universith of Minnesota, Minneapolis, MN; Mary R Rooney, Univ of Minnesota Twin-Cities, Minneapolis, MN; Faye L Norby, Univ of Minnesota, Minneapolis, MN; Niki C Oldenburg, Univ of MN Cardiovascular Div, Minneapolis, MN; Elsayed Z Soliman, Wake Forest Sch of Med, Winston Salem, NC; Alvaro Alonso, Emory Univ, Atlanta, GA; Jin O-uchi, Samuel C Dudley Jr., Pamela L Lutsey, Lin Yee Chen, Univ of Minnesota, Minneapolis, MN

11:30 AM

Board # 2038

Safety or Efficacy; Or Could We Have Both? A Focused Study of Prohibited Devices in the MRI Environment

**Robert W Biederman** , Loretta Gevenosky, Allegheny General Hosp, Pittsburgh, PA; Huma Samar, Allegheny General Hosp, Loma Linda, CA; Ronald Williams, June Yamrozik, Richard Lombardi, Moneal Shah, Francesco Mangini, Christopher Bonnet, Mark Doyle, Allegheny General Hosp, Pittsburgh, PA

11:30 AM

Board # 2039

Modified "34ms" Late Potential Criteria for Positive Saecg in ARVC to Improve Identification of VT Substrate

**Cory M Tschabrunn** , Univ of Pennsylvania, Philadelphia, PA; Erica S Zado, Hosp of the Univ of PA, Philadelphia, PA; Pasquale Santangeli, Univ of Pennsylvania, Philadelphia, PA; David S Frankel, Univ of Pennsylvania Health System, Philadelphia, PA; Gregory Supple, Univ of Pennsylvania, Philadelphia, PA; David J Callans, Hosp of the Univ of PA, Washington Crossing, PA; Francis E Marchlinski, Univ of Pennsylvania, Bala Cynwyd, PA

# Abstract Poster Session

## EA.APS.28 - Cardiac Arrhythmia in Special Patient Populations with Noncardiac Conditions

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2050

Evaluation Of Ventricular Arrhythmia Burden In Patients With End-stage Renal Disease On Dialysis With Cardiac Implantable Electronic Devices

**Evan Harmon** , Brittney Heard, Sula Mazimba, Rohit Malhotra, Brendan Bowman, Nishaki M Mehta, Univ of Virginia Health System, Charlottesville, VA

11:30 AM

Board # 2052

Post-operative Atrial Fibrillation After Liver Transplantation: Rare but Beware

**Gregory A Kendall** , Navid Berenji, Debanshu Roy, Hari Sayana, Auroa Badin, Univeristy of Texas Health San Antonio, San Antonio, TX; Manoj M Panday, Univ of Texas Health San Antonio, San Antonio, TX; Jayasree Pillarisetti, UT Health San Antonio, San Antonio, TX

11:30 AM

Board # 2053

Cannabis Use Disorder Increases Risk of Cardiac Arrhythmia Hospitalization in Young Adults

Rikinkumar S Patel, Griffin Memorial Hosp, Norman, OK; **Sowmya Madireddy** , Mamata Medical Coll, Khammam, India

11:30 AM

Board # 2054

Comparison of QT Interval Measurements Between a Smartphone Electrocardiogram and a 12-Lead Electrocardiogram in Patients Undergoing Maintenance Methadone Therapy in a Narcotic Treatment Center

Erika Titus-Lay, California Northstate Univ, Elk Grove, CA; Heather Jaynes, Elena Tomaselli-Muensterman, Purdue Univ, Indianapolis, IN; Todd Walroth, Eskenazi Health, Indianapolis, IN; Carol A. Ott, Purdue Univ, Indianapolis, IN; Gabriela Williams, Paul Moe, Eskenazi Health, Indianapolis, IN; **James E Tisdale** , Purdue Univ, Indianapolis, IN

11:30 AM

Board # 2055

Prevalence and Significance of Isolated Inferior T-Wave Inversion in Young Athletes

**Prashant Rao** , Beth Israel Deaconess Medical Ctr, Boston, MA; Max Weiss, Thomas Jefferson Univ Hosp, Philadelphia, PA; Chris Koilor, Thomas Jefferson Univ, Philadelphia, PA; Renee Langstaff, Arcadia Univ, Glenside, PA; Stanton Miller, Thomas Jefferson Univ, Philadelphia, PA; Margot Putukian, Princeton Univ, Princeton, NJ; John Gallucci, St Peter's Healthcare System, New Brunswick, NJ; Matthew W Martinez, Lehigh Valley Health Network, allentown, PA; david shipon, jefferson university hospital, phila, PA

11:30 AM

Poster Professor

Lee L Eckhardt, Madison, WI

11:30 AM

Board # 2057

Association of Atrial Fibrillation and Left Atrial Enlargement With Cognitive Function and Decline: The Atherosclerosis Risk in Communities Neurocognitive Study

**Michael J Zhang** , Faye Norby, Pamela Lutsey, Univ of Minnesota, Minneapolis, MN; Rebecca Gottesman, Johns Hopkins Univ, Bethesda, MD; Thomas H Mosley, Univ of Mississippi Medical Ctr, Jackson, MS; Rebecca Cogswell, Suma KONETY, Univ of Minnesota, Minneapolis, MN; Tze-Fan Chao, Taipei Veterans General Hosp, Taipei, Taiwan; Amil Shah, Scott Solomon, Brigham and Womens Hosp, Boston, MA; Alvaro Alonso, Emory Univ, Atlanta, GA; Lin Yee Chen, Univ of Minnesota, Minneapolis, MN

11:30 AM

Board # 2058

Diabetes Without Insulin Use is Not an Independent Risk Factor for Stroke or Death in Anticoagulated Patients With Atrial Fibrillation

**Raffaele De Caterina** , Univ of Pisa, Pisa, Italy; Giuseppe Patti, Univ of L'Aquila, Coppito, Italy; Johan Westerbergh, Uppsala Univ, Uppsala, Sweden; Justin Ezekowitz, Univ of Alberta, Edmonton, AB, Canada; Basil S Lewis, Lady Davis Carmel Medical Ctr, Haifa, Israel; Renato D Lopes, Duke Med, Durham, NC; John JV McMurray, BHF Cardiovascular Res Ctr, Glasgow, United Kingdom; Dan Atar, Oslo Univ Hosp Ullevål, Oslo, Norway; Maria Cecilia Bahit, INECO Neurociencias, Rosario, Argentina; Matyas Keltai, Hungarian Inst of Cardiology, Budapest, Hungary; Jose L Lopez-Sendon, Hosp Uuniversitario La Paz, Madrid, Spain; Witold Ruzyllo, Inst of Cardiology, Warsaw, Poland; Christopher B Granger, Duke Med, Durham, NC; John H Alexander, DUMC, Durham, NC; Lars Wallentin, Uppsala Univ, Uppsala, Sweden

11:30 AM

Board # 2059

Post Operative Atrial Fibrillation After Lung Transplant: Not That Benign

**Navid Berenji** , UT Health San Antonio, San Antonio, TX; Debanshu Roy, UT Health San Antonio, San Antonio; Gregory Kendall, Univ of Texas Health, San Antonio, TX; Evan Saenger, UT Health San Antonio, San Antonio; Auroa Badin, Manoj M Panday, UT Health San Antonio, San Antonio, TX; Dhanunjaya Lakkireddy, Univ of Kansas Health System, Kansas City, KS; Jayasree Pillarisetti, UT Health San Antonio, San Antonio, TX

11:30 AM

Board # 2060

In-Hospital Outcomes of Early vs Delayed Electrical Cardioversion in Hemodynamically Unstable Atrial Fibrillation Patients

**Richard Ogunti** , Olusayo Fadiran, Vishnu Mallipeddi, Nitheesha Ganta, Ahmad Awan, Olabisi Akanbi, Daniel Larbi, Howard Univ Hosp, Washington, DC

11:30 AM

Board # 2061

Age Criteria is Necessary for the Dose Reduction of Rivaroxaban in Patients With Atrial Fibrillation?

**Ki Hong Lee** , Chonnam Natl Univ Hospita, Gwangju, Korea, Republic of; Namsik Yoon, Chonnam Natl Univ Hosp, Gwangju

11:30 AM

Board # 2062

Under-Reporting and Under-Representation of Racial/Ethnic Minorities in Major Atrial Fibrillation Clinical Trials

**Ashish Sarraju** , Stanford Univ Sch of Med, Stanford, CA; David J Maron, Stanford Univ, Stanford, CA; Fatima Rodriguez, Stanford Cardiovascular Inst, Stanford, CA

# Abstract Poster Session

## CA.APS.05 - Cardiac Fibrosis and Inflammation

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 1093

Proteasome Priming by Cyclic Amp Signaling Protects Stressed Hearts in Mice

Penglong Wu, Univ of South Dakota, Vermillion, SD; Nirmal Parajuli, Megan Lewno, Univ South Dakota, Vermillion, SD; Jinbao Liu, Guangzhou Medical Univ, Guangzhou, China; **Xuejun Wang** , Univ South Dakota, Vermillion, SD

11:30 AM

Board # 1094

Mechanisms of Endothelial Klf2-Mediated Pleiotropic Effects of Statins on the Prevention and Treatment of Tac-Induced Pathological Cardiac Remodeling

Hongda Li, Yanfang Wang, Shanghai East Hosp - Tongji U, Shanghai, China; **Yuzhen Zhang** , Shanghai East Hosp - Tongji U, Pudong New Area Shanghai, China

11:30 AM

Board # 1095

Pressure Overload Activates a Neuroimmune Mechanism in the Spleen That Guides Adaptive Cardiac Remodeling Through Placental Growth Factor

**Daniela Carnevale** , Sapienza Univ/IRCCS Neuromed, Pozzilli, Italy; Sara Perrotta, Sapienza Univ of Rome, Rome, Italy; Raimondo Carnevale, IRCCS Neuromed, Pozzilli, Italy; Fabio Pallante, Sapienza Univ and IRCCS Neuromed, pozzilli, Italy; Lorenzo Carnevale, I.R.C.C.S. Neuromed, Pozzilli, Italy; Marialuisa Perrotta, Giuseppe Lembo, IRCCS Neuromed, Pozzilli, Italy

11:30 AM

Board # 1096

Adcy9 **Inactivation Improves Cardiac Function After Myocardial Infarction in Absence of Cholesterol Ester Transfer Protein**

**Marine Ferron** , Nolwenn Merlet, Mélanie Mecteau, Teodora Mihalache-Avram, Geneviève Brand, Marc-Antoine Gillis, Yanfen Shi, Eric Rheaume, Jean-claude Tardif, Montreal Heart Inst, Montreal, QC, Canada

11:30 AM

Board # 1097

Correlation of Cardiac Biomarkers and Myocardial Fibrosis: Results of the Multi-Ethnic Study of Atherosclerosis

**Henry A Tran** , Inova Medical Group, Fairfax, VA; Stephen L Seliger, Univ of Maryland Sch of Med, Baltimore, MD; Palak Shah, Leonard Ilkhanoff, Inova Heart and Vascular Inst, Falls Church, VA; Lori Daniels, UCSD Medical Ctr, Del Mar, CA; Christopher Defilippi, Inova, Falls Church, VA

11:30 AM

Board # 1098

A Novel Anti-inflammation and Anti-fibrosis Agent, Vcp979, Treatment Attenuates Ventricular Remodeling and Improves Cardiac Function in Murine Model of Myocardial Ischemia/Reperfusion Injury

**Bing H Wang** , Baker Heart and Diabetes Inst, Melbourne, Australia; Jing Liu, Qingshu Meng, Hao Cao, Xiaoting Liang, Rulin Zhuang, Xinyu Ge, Fang Lin, Tongji Univ Sch of Med, Shanghai, China; Kevin W Huang, Baker Heart and Diabetes Inst, Melbourne, Australia; Huimin Fan, Tongji Univ Sch of Med, Shanghai, China; Peter Scammells, Monash Univ, Parkville, Australia; Xiaohui Zhou, Zhongmin Liu, Tongji Univ Sch of Med, Shanghai, China

11:30 AM

Board # 1099

Cardiac Tissue Factor Regulates Inflammation and Hypertrophy in Mouse Model of Type 1 Diabetes Mellitus

**Anamika Singh** , Cibi M Dasan, Reddemma Sandireddy, Duke NUS Medical Sch, Singapore, Singapore; Nicole Tee, Natl Heart Ctr, Singapore, Singapore; Nigel Mackman, UNC, Chapel Hill, NC; Manvendra Singh, Duke-NUS Medical Sch, Singapore

11:30 AM

Board # 1100

A Mouse Model of Recurrent Myocardial Infarction Reports Diminished Emergency Hematopoiesis and Cardiac Inflammation

**Sebastian Cremer** , Maximillian Schloss, Claudio Vinegoni, MGH, Boston, MA; Shuang Zhang, MGH, Boston, IL; David Rohde, Feruglio Paolo Fumene, Schmidt Stephen, Wojtkiewicz Greg, MGH, Boston, MA; Ralph Weissleder, Filip K Swirski, Massachusetts General Hosp, Boston, MA; Matthias Nahrendorf, MGH, Boston, MA

11:30 AM

Poster Professor

Pilar Alcaide, Boston, MA

11:30 AM

Board # 1101

Cardiac Stim1 Silencing Prevents Physiological Cardiac Hypertrophy and Promotes Pathological Remodeling in Exercised Mice

**Ingrid M Bonilla** , Stephen Baine, The Ohio State Univ, Columbus, OH; Andriy Belevych, Sandor Gyorke, Ohio State Univ, Columbus, OH

11:30 AM

Board # 1102

Influenza Infection Exacerbates Diet-Induced Atherosclerosis in Apolipoprotein Gene-Deficient Mice

**Radha Gopal** , Michael A Marinelli, Lacee J Richwalls, Nicholas J Constantinesco, John Alcorn, Univ of Pittsburgh, Pittsburgh, PA

11:30 AM

Board # 1103

A Biomimetic Assay for Rapid Screening of Differential Response of Anti-Inflammatory Therapeutics in Mouse and Human Cells

**Qingliang Yang** , Jordan Langston, Yuan Tang, Fariborz Soroush, Mohammad F Kiani, Laurie Kilpatrick, Temple Univ, Philadelphia, PA

11:30 AM

Board # 1104

Pathological Features Correlate With Clinical Manifestations in Patients With Obstructive Hypertrophic Cardiomyopathy Undergoing Septal Myectomy

**Hao Cui** , Juliano Lentz Carvalho, Mayo Clinic, Rochester, MN; Rick A Nishimura, Mayo Clinic Rochester, Rochester, MN; Jeffrey B Geske, Joseph A Dearani, Brian Lahr, Steve R Ommen, Joseph John Maleszewski, Hartzell V Schaff, Mayo Clinic, Rochester, MN

11:30 AM

Board # 1105

An Efficient Method for Mapping Heterogenous 3-dimensional (3D) Infarct Structure in Myocardial Injury Models

**Tom Liu** , Virginia Tech Carilion Sch of Med, Roanoke, VA; Xiaobo Wu, Robert G Gourdie, Fralin Biomedical Res Instutute, Roanoke, VA

11:30 AM

Board # 1106

Effect of Remote Ischemic Postconditioning on Inflammatory Cytokines, Cardiac Damage, Ventricular Function, and Mortality in Lipopolysaccharide-Induced Sepsis

**Takashi Honda** , Quan He, Fangfei Wang, Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; Andrew N Redington, Cincinnati Children's Hosp, Cincinnati, OH

# Abstract Poster Session

## EA.APS.23 - Cardiac Resynchronization Therapy Optimization and Outcomes

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2000

Longest Paced versus Sensed Electrical Delay Programming in Cardiac Resynchronization Therapy Defibrillator Patients With Quadripolar Lv Leads: Results From the Pased-crt Randomized Trial

**Raffaele Corbisieror** , Pedram Kazemian, JoEllen Schmidt, Deborah Heart and Lung Ctr, Browns Mills, NJ; David R Muller, SJM, Sicklerville, NJ

11:30 AM

Board # 2001

Cardiac Resynchronization Therapy Improves Diastolic Function and Reduces New Onset Atrial Fibrillation in Patients With Prolonged Atrioventricular Interval: The Pilot Randomized Controlled Real-crt Study

**Giovanni L Botto** , Sant'Anna Hosp, San Fermo Della Battaglia, Italy; Assunta Iuliano, Clinica Mediterranea, Naples, Italy; Eraldo Occhetta, Ospedale Maggiore Della Carità, Novara, Italy; Giuseppina Belotti, A.O.OSP. Treviglio Caravaggio, Bergamo, Italy; Giovanni Russo, Sant'Anna Hosp, San Fermo Della Battaglia, Italy; Monica Campari, Sergio Valsecchi, Boston Scientific Italia, Milan, Italy; Giuseppe Stabile, Casa di Cura San Michele, Maddaloni (CE), Italy

11:30 AM

Board # 2002

Optimal Fusion vs. Biventricular Pacing in Cardiac Resynchronization Therapy: Long-Term Results of 540 Consecutive Patients

**Radu G. Vatasescu** , Dan-Andrei Radu, Clinic Emergency Hosp, Bucharest, Romania; Corneliu Iorgulescu, Clinical Emergency Hosp of Bucharest, Bucharest, Romania; Stefan N Bogdan, Silvia Iancovici, Alexandrina Nastasa, Cosmin Cojocaru, Alexandru Badiul, Clinic Emergency Hosp, Bucharest, Romania

11:30 AM

Board # 2004

High Precision Acute Haemodynamic Evaluation of Personalisation of Endocardial Left Ventricular Pacing Site in Patients With Heart Failure

**Charles Butcher** , Harefield Hosp, London, United Kingdom; Sayed Sohaib, Imperial Coll London, London, United Kingdom; Matthew Shun-Shin, Imperial Coll, London, United Kingdom; Ross Haynes, Habib Khan, Harefield Hosp, London, United Kingdom; Andreas Kyriacou, Northern General Hosp, Sheffield Teaching Hosp NHS Trust, Sheffield, United Kingdom; Rui Shi, Royal Brompton Hosp, London, United Kingdom; Emily Cantor, Zhong Chen, Harefield Hosp, London, United Kingdom; Sandeep Panikker, Univ Hosp Coventry and Warwickshire, Coventry, United Kingdom; Shouvik Haldar, Harefield Hosp, London, United Kingdom; John Cleland, Univ of Glasgow, Glasgow; Hussain Wajid, Harefield Hosp, London, United Kingdom; Vias Markides, Royal Brompton Hosp, London; David Jones, Harefield Hosp, London, United Kingdom; Rebecca E Lane, Royal Brompton, Middlesex, United Kingdom; Zachary Ian Whinnett, Imperial Coll, London, United Kingdom; Mark Mason, Harefield Hosp, London, United Kingdom; Darrel Francis, Imperial Coll, London, United Kingdom; Tom Wong, Royal Brompton Hosp, London, United Kingdom

11:30 AM

Board # 2005

CRT versus RV Pacing--Can We Reduce Readmissions in HFpEF Through Better Device Selection?

**Esseim Sharma** , Michael Wu, Brown Univ, Providence, RI; Wasiq Sheikh, Anshul Parulkar, Rhode Island Hosp, Providence, RI; Brian Daniel McCauley, Malik Bilal Ahmed, Brown Univ, Providence, RI; Lauren Rousseau, Cardiovascular Inst, Providence, RI; Antony F Chu, Brown Univ, Providence, RI

11:30 AM

Board # 2006

Cardiac Resynchronization Therapy In Left Ventricular Non-compaction: Long-term Results In A Series Of 40 Patients

**Radu Dan-Andrei** , Corneliu N Iorgulescu, Stefan N Bogdan, Alexandrina Nastasa, Cosmin Cojocaru, Alexandru Badiul, Radu Gabriel Vatasescu, Clinic Emergency Hosp, Bucharest, Romania

11:30 AM

Board # 2007

Sex Differences in Outcomes After His-Bundle Pacing for Cardiac Resynchronization Therapy

**Nidhi Madan** , Christina K. Anderson, Grzegorz M. Pietrasik, Richard G Trohman, Annabelle Santos Volgman, Jillian L. Hanifin, Rush Univ Medical Ctr, Chicago, IL; Pugazhendhi Vijayaraman, Geisinger Heart Inst, Wilkes-Barre, PA; Kenneth A Ellenbogen, Medical Coll of Virginia, Richmond, VA; Parikshit Sharma, Rush Univ Medical Ctr, Chicago, IL

11:30 AM

Board # 2008

Impact of Cardiac Resynchronization Therapy on IL-1β and High-Sensitivity C-reactive Protein in Heart Failure

**Kenneth C Bilchick** , Hema Kothari, James C Garmey, Aditya Narayan, Omar Abdullah, Coleen A McNamara, Univ of Virginia Health System, Charlottesville, VA

11:30 AM

Board # 2009

Multipoint Pacing With Septal Fusion Using an Adaptive Av Algorithm to Optimize Crt Patients

**Raffaele Corbisieror** , Deborah Heart and Lung Ctr, Millstone Twsp, NJ; David R Muller, SJM, Sicklerville, NJ

# Abstract Poster Session

## AC.APS.08 - Cardiovascular Vulnerability: New Insights

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 4053

Evolocumab and Cardiovascular Outcomes in Patients With Recent Myocardial Infarction: Analysis From FOURIER

**Baris Gencer** , TIMI Study Group, Boston, MA; François Mach, Univ Hosp Geneva, Geneva, Switzerland; Sabina A Murphy, TIMI Study Group, Boston, MA; Gaetano M De Ferrari, IRCCS Policlinico San Matteo, Pavia, Italy; Kurt Huber, Wilhelminenspital, Vienna, Austria; Basil S Lewis, Lady Davis Carmel Med Ctr, Haifa, Israel; Jorge Ferreira, Hosp de Santa Cruz, Carnaxide, Portugal; Christopher E Kurtz, AMGEN, Thousand Oaks, CA; Huei Wang, AMGEN, Newbury Park, CA; Narimon Honarpour, AMGEN, Thousand Oaks, CA; Anthony C Keech, NHMRC Clinical Trials Ctr, Camperdown Sydney, Australia; Peter S Sever, Imperial college London, London, United Kingdom; Terje Rolf Pedersen, Oslo Univ Hosp, Oslo, Norway; Marc S Sabatine, Robert P Giugliano, TIMI Study Group, Boston, MA

11:30 AM

Board # 4051

Dissociation of Circulating Cardiac Troponin I Concentrations From the Physiological Significance of Coronary Artery Disease

**Brian R Weil** , Ibrahim El Masri, Rebeccah F Young, Cody Smith, Stephanie Comer, Alex Tischler, John M Canty, Univ at Buffalo, Buffalo, NY

11:30 AM

Board # 4059

Pregnancy After Spontaneous Coronary Artery Dissection: A Case Series of 22 Women and 31 Pregnancies

**Marysia S Tweet** , Kathleen A Young, Carl H Rose, Patricia J Best, Rajiv Gulati, Sharonne N Hayes, Mayo Clinic, Rochester, MN

11:30 AM

Board # 4055

Galectin-3 and Mortality in Japanese Patients With Suspected or Known Coronary Artery Disease: From the ANOX Study

**Hiromichi Wada** , Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan; Kazuhiko Kotani, Jichi Medical Univ, Shimotsuke, Japan; Masahiro Suzuki, Natl Hosp Organization Saitama Hosp, Wako, Japan; Morihiro Matsuda, Natl Hosp Organization Kure Medical Ctr and Chugoku Cancer Ctr, Kure, Japan; Yoichi Ajiro, Natl Hosp Organization Yokohama Medical Ctr, Yokohama, Japan; Tsuyoshi Shinozaki, Natl Hosp Organization Sendai Medical Ctr, Sendai, Japan; Satoru Sakagami, Natl Hosp Organization Kanazawa Medical Ctr, Kanazawa, Japan; Kazuya Yonezawa, Natl Hosp Organization Hakodate Natl Hosp, Hakodate, Japan; Masatoshi Shimizu, Natl Hosp Organization Kobe Medical Ctr, Kobe, Japan; Junichi Funada, Natl Hosp Organization Ehime Medical Ctr, Toon, Japan; Takashi Takenaka, Natl Hosp Organization Hokkaido Medical Ctr, Sapporo, Japan; Yukiko Morita, Natl Hosp Organization Sagamihara Natl Hosp, Sagamihara, Japan; Toshihiro Nakamura, Natl Hosp Organization Kyushu Medical Ctr, Fukuoka, Japan; Kazuteru Fujimoto, Natl Hosp Organization Kumamoto Medical Ctr, Kumamoto, Japan; Hiromi Matsubara, Natl Hosp Organization Okayama Medical Ctr, Okayama, Japan; Toru Kato, Natl Hosp Organization Tochigi Medical Ctr, Utsunomiya, Japan; Takashi Unoki, Daisuke Takagi, Kyohma Wada, Miyaka Wada, Moritake Iguchi, Nobutoyo Masunaga, Mitsuru Ishii, Mitsuru Abe, Masaharu Akao, Koji Hasegawa, Natl Hosp Organization Kyoto Medical Ctr, Kyoto, Japan

11:30 AM

Board # 4057

The Association Between Angiotensin Converting Enzyme Inhibitors or Angiotensin Receptor Blockers With Major Adverse Cardiovascular Events in Patients With Coronary Artery Disease

**Maneesh Sud** , Sunnybrook Health Sciences Ctr, Toronto, ON, Canada; Paymon Azizi, Univ of Toronto, Toronto, ON, Canada; Maria Koh, Alice Chong, Dennis T Ko, ICES, Toronto, ON, Canada; Cynthia Jackevicius, Western Univ, Los Angeles, CA

11:30 AM

Board # 4054

Assessment of Genetic Variants in European Patients With Coronary Spasm

Roman Tremmel, Elke Schaeffeler, Dr. Margarete Fischer-Bosch Inst of Clinical Pharmacology, Stuttgart, Germany; Per Hoffmann, Markus M. Noethen, Inst of Human Genetics, Univ of Bonn, Bonn, Germany; Valeria Martínez Pereyra, Incifer Broders, Raffi Bekeredjian, Udo Sechtem, Robert-Bosch-Krankenhaus, Stuttgart, Germany; Matthias Schwab, Dr. Margarete Fischer-Bosch Inst of Clinical Pharmacology, Stuttgart, Germany; **Peter Ong** , Robert-Bosch-Krankenhaus, Stuttgart, Germany

11:30 AM

Board # 4058

Long-term Antidiabetic Treatment by Dapagliflozin Provides Multiple Antiatherosclerotic Effects Independent of Diabetic Improvement for Type-2 Diabetics With Coronary Artery Disease Receiving Statin or Sartan

**Tatsuaki Murakami** , Kazuo Ohsato, Fukui Cardiovascular Ctr, Fukui, Japan

11:30 AM

Board # 4056

ALP Levels Predict Adverse Cardiovascular Outcomes and Cognitive Impairment in High Risk Patients

**Kausik K. Ray** , Imperial Coll London, London, United Kingdom; Jeffrey L. Cummings, Cleveland Clinic Lou Ruvo Ctr for Brain Health, Las Vegas, NV; Mathias L. Haarhaus, Karolinska Instt, Karolinska Univ Hosp, Solna, Sweden; Peter P. Toth, CGH Medical Ctr, Sterling, IL; Stephen Nicholls, Monash Health, Victoria, Australia; Henry N. Ginsberg, Irving Inst for Clinical & Translational Res, Columbia Univ, New York, NY; Bengt Winblad, Karolinska Instt, Huddinge, Sweden; Henrik Zetterberg, Sahlgrenska Acad, Univ of Gothenburg, Gothenburg, Sweden; Michael Sweeney, Jan O. Johansson, Resverlogix Inc., San Francisco, CA; Ewelina Kulikowski, Kenneth Lebioda, Aziz Khan, Christopher Halliday, Resverlogix Corp., Calgary, AB, Canada; Carmine Zoccali, CNR-IFC Reggio Calabria Unit, Reggio Calabria, Italy; Kamyar Kalantar-Zadeh, Sch of Med, Univ of California Irvine, Orange, CA; Gregory G. Schwartz, Sch of Med, Univ of Colorado, Aurora, CO

11:30 AM

Board # 4050

Effect of Dapagliflozin in Reducing Recurrent Myocardial Infarction of Different Infarct Types and Sizes: Insights From Declare-Timi 58

**Remo H M Furtado** , Brigham and Women's Hosp, Boston, MA; Marc P Bonaca, CPC Clinical Res, Aurora, CO; Thomas Alexander Zelniker, Brigham and Women's Hosp, Boston, MA; Itamar Raz, Diabetes Medical Ctr, Tel Aviv, Israel; Erica Goodrich, Brigham and Women's Hosp, Boston, MA; Ofri Mosenzon, Hadassah Hebrew Univ Hosp, Jerusalem, Israel; Sabina Murphy, Deepak L Bhatt, Brigham and Women's Hosp, Boston, MA; Lawrence A Leiter, Univ of Toronto, Toronto, ON, Canada; Darren K McGuire, Univ Texas Southwestern Med Ctr, Dallas, TX; John Wilding, Univ of Liverpool, Liverpool, United Kingdom; Ingrid Ami Gause-Nilsson, Anna Maria Langkilde, Astrazeneca, Mölndal, Sweden; Marc S Sabatine, TIMI Study Group, Boston, MA; Stephen Wiviott 02115, Brigham and Women's Hosp, Boston, MA

11:30 AM

Board # 4052

Higher Activation of the Ventromedial Prefrontal Cortex During Mental Stress Predicts Major Cardiovascular Disease Events in Patients With Coronary Artery Disease

**Kasra Moazzami** , Matthew T Wittbrodt, Bruno B Lima, Emory Univ, Atlanta, GA; Jonathon A Nye, Puja K Mehta, Arshed A Quyyumi, Emory Univ, Atlanta, GA; J Douglas Bremner, Amit J Shah, Emory Univ, Atlanta, GA; Viola Vaccarino, Emory Univesity

11:30 AM

Poster Professor

Stephen J Nicholls, Australia

# Abstract Poster Session

## AT.APS.19 - Effectors of Endothelial State: From E-Cigarettes to Molecules to Disease States

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 1029

Juul and Previous Generation E-cigarette Exposure Comparably Impair Vascular Endothelial Function

**Poonam Rao** , Jiangtao Liu, Matthew L Springer, UCSF, San Francisco, CA

11:30 AM

Board # 1030

Lower Flow-Mediated Dilation is Associated With Higher Incidence of Cardiac and Cerebrovascular Events in Patients With Coronary Artery Disease

**Teruyoshi Nemoto** , Kitasato Univercity, Sagamihara Kanagawa, Japan; Yoshiyasu Minami, Minako Yamaoka-tojo, Ayami Kato, Aritomo Katsura, Toshimitsu Sato, Yusuke Muramatsu, Ryota Kakizaki, Takuya Hashimoto, Kazuhiro Fujiyoshi, Kentaro Meguro, Kitasato Univ, Sagamihara Kanagawa, Japan; Takao Shimohama, Kitasato Univ, Sagamihaga Kanagawa, Japan; Junya Ako, Kitasato Univ, Sagamihara Kanagawa, Japan

11:30 AM

Board # 1031

Long-Term Vascular Function, Following Aortic Valve Replacement for Stenosis, Vitally Changes in Conjunction With Effective Orifice Area Index

**Noboru Motomura** , Univ of Toho, Sakura Medical Ctr, Chiba, Japan; Aya Saito, Toho Univ Sakura Medical Ctr, Chiba, Japan; Yuya Ito, Univ of Toho, Sakura Medical Ctr, Chiba, Japan

11:30 AM

Board # 1032

Brachial Arterial Stiffness Differs From Aortic Stiffness in Relation to Cardiovascular Risk Factors

**Ueda Tomohiro** , Ohchi Municipal Hosp, Shimane, Japan; Hiroki Teragawa, JR Hiroshima Hosp, Hiroshima, Japan; Chikage Oshita, JR Hiroshima Hosp, Hiroshima, Japan; Shuichi Nomura, Yuichi Fujii, JR Hiroshima Hosp, Hiroshima, Japan

11:30 AM

Board # 1033

Epsin-Mimetic UPI Peptide Delivery Strategies From Electrospun Meshes Improve Endothelial Cell Attachment for Vascular Tissue Engineering

Mahyar Sameti, Ana R Martinez-Dehesa, Florida Inst of Technology, Melbourne, FL; Hong Chen, Harvard Medical Sch, Boston, MA; **Chris A Bashur** , Florida Inst of Technology, Melbourne, FL

11:30 AM

Board # 1034

Reversal of the Thrombin Generation Inhibitory Effect of Apixaban, Betrixaban, Edoxaban and Rivaroxaban by Andexanet Alpha May Be Associated With Increased Thrombogenesis

**Walter Jeske** , Loyola Univ Medical Ctr, Maywood, IL; Fakiha Siddiqui, Loyola Univ Chicago, Maywood, IL; Alfonso J Tafur, Northshore Univ Healthsystem, Skokie, IL; Ahmed Kouta, Loyola Univ Chicago, Chicago, IL; Debra Hoppensteadt, Loyola Univ Chicago, Maywood, United States Minor Outlying Islands; Eduardo Ramacciotti, Loyola Univ Medical Ctr, Maywood, IL; Jawed Fareed, Loyola Univ Medical Cent, Maywood, IL; Bruce Lewis, Loyola Univ Medical Ctr, Maywood, IL

11:30 AM

Board # 1035

Food Restriction Augmented Alpha1-Adrenergic Mediated Contraction in Rats Mesenteric Arteries

**Rany Vorn** , Hae Young Yoo, Chung Ang Univ, Seoul, Korea, Republic of

11:30 AM

Board # 1036

Peripheral Endothelial Function in Patients With Hypertrophic Cardiomyopathy

**Shivtej Kaushal** , Tadeo Diaz Balderrama, Michael E Widlansky, Medical Coll of Wisconsin, Milwaukee, WI; Joshua Meskin, Medical Coll of Wisconsin, Wauwatosa, WI; Scott Cohen, Medical Coll of Wisconsin, Milwaukee, WI

11:30 AM

Board # 1037

Acetaldehyde-Induced Relaxation of Superior Mesenteric Artery: Potential Role in Postprandial Hyperemia

Lexiao Jin, Pawel Lorkiewicz, Marina Malovichko, Aruni Bhatnagar, sanjay srivastava, **Daniel J Conklin** , Univ of Louisville, Louisville, KY

11:30 AM

Board # 1039

Association Between Endothelial Function Measured by Enclosed Zone Flow-mediated Vasodilation and Cardiovascular Risk Factors

**Masato Kajikawa** , Hiroshima Univ, Hiroshima, Japan; Haruka Morimoto, Nihon Kohden Co, Tokyo, Japan; Haruki Hashimoto, Hiroshima Univ, Hiroshima, Japan; Shogo Matsui, Hiroshima Univ Graduate Sch of Biomedical Sciences, Hiroshima, Japan; Tatsuya Maruhashi, Hiroshima Univ, Hiroshima Japan, Japan; Shinji Kishimoto, Hiroshima Univ, Hiroshima Japan, Japan, Hiroshima, Japan; Yuji Takaeko, Takayuki Yamaji, Takahiro Harada, Takayuki Hidaka, Farina Mohamad Yusoff, Hiroshima Univ, Hiroshima, Japan; Yasuki Kihara, Hiroshima Univ Hosp, Hiroshima, Japan; Toshio Tsuji, Yukihito Higashi, Hiroshima Univ, Hiroshima, Japan

# Abstract Poster Session

## EP.APS.26 - Electrocardiographic Predictors of Cardiovascular Risk

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 3031

T Peak - T End Interval on the Prehospital 12-lead ECG is a Strong Predictor of Adverse Cardiac Events in Patients With Suspected Acute Coronary Syndrome

**Mohammad Alhamaydeh** , Conemaugh Memorial Medical Ctr, Pittsburgh, PA; Abdullah Ahmad, Univ of Pittsburgh, Pittsburgh, PA; Ziad Faramand, Univ of Pittsburgh Medical Ce, Pittsburgh, PA; Samir Saba, UPMC, Pittsburgh, PA; Richard Gregg, Philips Healthcare, Andover, MA; Christian Martin-Gill, Clifton W Callaway, Salah S Al-Zaiti, Univ of Pittsburgh, Pittsburgh, PA

11:30 AM

Board # 3032

Prevalence and Prognostic Significance of Location of ST-T Abnormalities Accompanying Minor Q Waves

**Ho Lim Lee** , Muhammadimtiaz Ahmad, Yabing Li, Wake Forest Sch of Med, Winston Salem, NC; Richard Stacey, Wake Forest Univ, Winston Salem, NC; Sanjay Kumar Maheshwari, Liaquat Univ of Medical and Health Sciences, Jamshoro, Pakistan; Elsayed Z Soliman, Wake Forest Sch of Med, Winston Salem, NC

11:30 AM

Board # 3034

Natural History and Clinical Outcomes of Inappropriate Sinus Tachycardia: The Mayo Clinic Experience

**Samuel A. Shabtaie** , Chance M. Witt, Samuel J. Asirvatham, Mayo Clinic, Rochester, MN

11:30 AM

Board # 3035

Qtc Prolongation is Associated With Cardiovascular Events in Male Patients With Cardiovascular Risk and Without Apparent Cardiovascular Disease: The Japan Morning Surge Home Blood Pressure (J-HOP) Study

**Takafumi Okuyama** , Jichi Medical Univ Hosp, Shimotsuke-shi, Japan; Tomoyuki Kabutoya, Jichi Medical Univ, Shimotsuke Tochigi, Japan; Satoshi Hoshide, Jichi Medical Univ, Shimotsuke, Japan; Kazuomi Kario, Jichi Medical Univ, Tochigi-ken, Japan

11:30 AM

Board # 3036

Association of Electrocardiographic Left Atrial Abnormality and B-type Natriuretic Peptide in a Large Japanese Cohort: A Report From the Nippon Data2010 Research Group

**Satoshi Shoji** , Keio Univ, Shinjyuku, Tokyo, Japan; Shun Kohsaka, Mitsuaki Sawano, Keio Univ, Tokyo, Japan; Tomonori Okamura, Aya Hirata, Keio Univ, Shinjyuku, Tokyo, Japan; Daisuke Sugiyama, Keio Univ, Matsumoto City, Japan; Takayoshi Ohkubo, Tohoku Univ Hosp, Tokyo, Japan; Yasuyuki Nakamura, Ryukoku Univ, Otsu, Japan; Makoto Watanabe, Natl Cerebral and Cardiovascular Ctr, Ishikawaken, Japan; Aya Kadota, Hirotsugu Ueshima, Shiga Univ of Medical Science, Otsu, Japan; Akira Okayama, Natl Cardiovascular Ctr, Japan, Suita, Japan; Katsuyuki Miura, Shiga Univ of Medical Science, Shiga, Japan

11:30 AM

Board # 3037

Electrocardiographic Atrial Cardiomyopathy Markers and Risk of Atrial Fibrillation After Cardiac Surgery

Ilkka O Ruohonen, Antti Eranti, Arto Relander, Sami Sinisilta, Veikko Lahtinen, Juho Markku Jalkanen, Turku Univ Hosp, Turku, Finland; Sirpa Jalkanen, Maija Hollmen, Univ of Turku, Turku, Finland; Juhani Airaksinen, Turku Univ Hosp, Washington, DC; Fausto Biancari, Jarmo Gunn, Turku Univ Hosp, Turku, Finland; **Tuomas O Kiviniemi** , Brigham and Women's Hosp, Boston, MA

11:30 AM

Board # 3038

Absence of Electrocardiographic Left Ventricular Hypertrophy is Associated With Increased Mortality After TAVR

**Robert Zhang** , The Hosp of the Univ of Pennsylvania, Philadelphia, PA; Mohammad El-Hajjar, Anthony Nappi, Mikhail Torosoff, Augustin Delago, Albany Medical Ctr, Albany, NY

11:30 AM

Board # 3039

Recurrence of Atrial Fibrillation Following Pulmonary Vein Isolation: Development of a Multivariate Predictive Model Using Real-world Data

**Adam E Berman** , Gaither H. Horde, Aaron Gopal, Paul T. Maddux, Deepak Ayyala, Medical Coll of Georgia, Augusta, GA

11:30 AM

Board # 3040

The Novel Inflammatory Marker Glyc a and Incident Atrial Fibrillation in the Multi-ethnic Study of Atherosclerosis

**Sunyoung Jang** , Oluseye Ogunmoroti, Johns Hopkins Univ Sch of Med, Baltimore, MD; Di Zhao, Johns Hopkins Univ Bloomberg Sch of Public Health, Baltimore, MD; Oluwaseun E Fashanu, Saint Agnes Hosp, Baltimore, MD; Martin Tibuakuu, St. Luke's Hosp, Chesterfield, MO; Eve-Marie Benson, Johns Hopkins Univ Bloomberg Sch of Public Health, Baltimore, MD; Faye L Norby, Univ of Minnesota, Minneapolis, MN; James D Otvos, LabCorp, Morrisville, NC; Susan R Heckbert, Univ of Washington, Seattle, WA; Moyses Szklo, Johns Hopkins Univ Bloomberg Sch of Public Health, Baltimore, MD; Erin D Michos, Johns Hopkins Univ Sch of Med, Baltimore, MD

# Abstract Poster Session

## EP.APS.25 - Environmental and Neighborhood Influences on Health

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 3021

The Impact of Area Deprivation on the Cardiac Mortality Among Young People: A Longitudinal Analysis of Scottish Linkage Data From 1991-2010

**Kai Jin** , Lis Neubeck, Iain Atherton, Edinburgh Napier Univ, Edinburgh, United Kingdom

11:30 AM

Board # 3022

Spatiotemporal Association Between Violent Crime And Ambulatory Elevations In Systolic Blood Pressure In Chicago

**W. Wyatt Wilson** , Rhys FM Chua, Stephanie A Besser, Elizabeth L. Tung, Marynia Kolak, Corey E Tabit, Univ of Chicago, Chicago, IL

11:30 AM

Board # 3023

Association of Particulate Matter and Incident Stroke in Atrial Fibrillation

**Zachary Rhinehart** , UPMC, Pittsburgh, PA; Ellen Kinnee, Melissa Saul, Univ of Pittsburgh, Pittsburgh, PA; Jane Clougherty, Drexel Sch of Public Health, Philadelphia, PA; Jared W Magnani, Univ of Pittsburgh, Pittsburgh, PA

11:30 AM

Board # 3024

Rural versus Urban Areas: Mortality Differences in the United States Among Patients With ST-Elevation Myocardial Infarction

**Gian Lima** , Kathir Balakumaran, Agnes Kim, Univ of Connecticut, Hartford, CT

11:30 AM

Board # 3026

Increasing Role of Public Access Defibrillation in the Chain of Survival in Japan

**Hideo Mitamura** , Tachikawa Hosp, Tokyo, Japan

11:30 AM

Board # 3027

Effect of Change in Temperature and Hospital Admissions for Cardiovascular Disease: A Nationwide Study From the Japanese Registry of All Cardiac and Vascular Diseases

**Kihei Yoneyama** , Takumi Higuma, Kanaka Teramoto, Mika Watanabe, Yuki Ishibashi, Masaki Izumo, Yasuhiro Tanabe, Tomoo Harada, Yoshihiro J Akashi, St. Marianna Univ Sch of Med, Kawasaki, Japan

11:30 AM

Board # 3028

Association Between the Built Environment and Heart Failure Progression in an Urban Retrospective Cohort Study

**Yiye Zhang** , Subhi Alaref, Weill Cornell Med, New York, NY; Mohammad Tayarani, Cornell Univ, Ithaca, NY; Evan Sholle, Arindam RoyChoudhury, Weill Cornell Med, New York, NY; H. Oliver Gao, Cornell Univ, Ithaca, NY; James K Min, Weill Cornell Med, New York, NY; Jyotishman Pathak, Weill Cornell Medical Coll, New York, NY; Jessica Ancker, Weill Cornell Med, New York, NY

11:30 AM

Board # 3030

Effect Modification of Neighborhood Greenness on the Relationship Between Ambient Air Pollution and Arterial Stiffness

**Daniel W Riggs** , Daniel J Conklin, Ray Yeager, Natasha DeJarnett, Rachel J Keith, Andrew Paul DeFilippis, Shesh N Rai, Aruni Bhatnagar, Univ of Louisville, Louisville, KY

# Abstract Poster Session

## EP.APS.27 - Epidemiology of Cardiovascular and Peripheral Vascular Disorders

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 3041

Serum Ceramides and Type 2 Diabetes Are Mutually Independent Predictors of Cardiovascular Events in Patients With Peripheral Artery Disease

Andreas Leiherer, Axel Muendlein, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; **Christoph H Saely** , Private Univ of the Principality of Liechtenstein, Triesen, Liechtenstein; Reijo Laaksonen, Mitja Lääperi, Zora Biosciences, Espoo, Finland; Alexander Vonbank, Arthur Mader, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Peter Fraunberger, Medical Central Labs, Feldkirch, Austria; Iris Baumgartner, Joern F Dopheide, Heinz Drexel, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland

11:30 AM

Board # 3042

Type 2 Diabetes as a Predictor of Cardiovascular Events in Peripheral Artery Disease versus Coronary Artery Disease

**Christoph H Saely** , Private Univ of the Principality of Liechtenstein, Triesen, Liechtenstein; Alexander Vonbank, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Christine Heinzle, Daniela Zanolin-Purin, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; Arthur Mader, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Marc Schindewolf, Iris Baumgartner, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland; Andreas Leiherer, Axel Muendlein, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; Heinz Drexel, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland

11:30 AM

Board # 3043

Lipid Parameters in Peripheral Artery Disease Versus Coronary Artery Disease Patients With Type 2 Diabetes

**Christoph H Saely** , Private Univ of the Principality of Liechtenstein, Triesen, Liechtenstein; Alexander Vonbank, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Christine Heinzle, Daniela Zanolin-Purin, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; Joern F Dopheide, Iris Baumgartner, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland; Arthur Mader, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Andreas Leiherer, Axel Muendlein, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; Heinz Drexel, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland

11:30 AM

Board # 3044

Type 2 Diabetes is a Strong Predictor for LDL Cholesterol Target Achievement in Patients With Peripheral Artery Disease

Simon Sternbauer, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; Alexander Vonbank, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Christine Heinzle, Daniela Zanolin-Purin, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; Joern F Dopheide, Iris Baumgartner, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland; Arthur Mader, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Andreas Leiherer, Axel Muendlein, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; Heinz Drexel, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland; **Christoph H Saely** , Private Univ of the Principality of Liechtenstein, Triesen, Liechtenstein

11:30 AM

Board # 3045

Arterial Stiffness is Associated With Vascular Calcification Measured as Carotid Plaque: Finding a Pulse Wave Velocity Cut-off Point for Risk Stratification

**Marcos A Sanchez-Gonzalez** , Larkin Health System, South Miami, FL; Renata Böcskei, Semmelweis Medical Univ, Budapest, Hungary; Troy Grogan, MedScience Res Group, Delray Beach, FL; Miklos Illyés, Univ of Pécs, Pecs, Hungary

11:30 AM

Board # 3046

The Coefficient of Variation of Fourth Harmonic Amplitude of Radial Pulse Wave Predicts Major Adverse Cardiovascular Events in Asymptomatic Patients With Type 2 Diabetes

kuomeng Liao, Zhongxiao Branch of Taipei City Hosp, Taipei, Taiwan; **Chi-Wei Chang** , Mii-Ann medical center, Taipei, Taiwan; Yi-Ting Chang, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Sheng-Hung Wang, Mii-Ann Medical Ctr, Taipei, Taiwan; Ying jin Chen, Zhongxiao Branch of Taipei City Hosp, Taipei, Taiwan; gin-chung wang, JinMu Health Technology, Taipei, Taiwan

11:30 AM

Board # 3047

Aortic Stenosis Incidence, Management and Outcomes

**Emily Patricia Hiltner** , Stavros Zinonos, Rutgers-Robert Wood Johnson Univ Hosp, New Brunswick, NJ; Davit Sargsyan, John B Kostis, Rutgers-Robert Wood Johnson Medical Sch, New Brunswick, NJ; Javier Cabrera, Nora Cosgrove, Rutgers-Robert Wood Johnson Univ Hosp, New Brunswick, NJ; Abel E Moreyra, Rutgers RWJ Medical Sch, New Brunswick, NJ; Issam Moussa, Carle Illinois Coll of Med, Champaign, IL; William J. Kostis, Rutgers Robert Wood Johnson Medical Sch, New Brunswick, NJ

11:30 AM

Board # 3048

Absence of Coronary Artery Disease by Coronary Angiography is Associated With a Lower Risk of Myocardial Infarction Than in the General Population

**Kevin Kris Warnakula Olesen** , Morten Madsen, Christine Gyldenkerne, Aarhus Univ Hosp, Aarhus N, Denmark; Pernille Gro Thrane, Aarhus Univ Hosp, Aarhus, Denmark; Troels Thim, Lisette Okkels Jensen, Aarhus Univ Hosp, Aarhus N, Denmark; John W Eikelboom, McMaster Univ HGH, Hamilton, ON, Canada; Hans Erik Bøtker, Henrik Toft Sørensen, Michael Maeng, Aarhus Univ Hosp, Aarhus N, Denmark

11:30 AM

Board # 3050

Contemporary Aspirin Use for Cardiovascular Disease Prevention

**Russell V Luepker** , Jeremy R Van't Hof, Niki C Oldenburg, Jeffrey R Misialek, John R Finnegan, Milton Eder, Sue Duval, Univ of Minnesota, Minneapolis, MN

11:30 AM

Poster Professor

Dharam Kumbhani, Dallas, TX

# Abstract Poster Session

## EP.APS.24 - Epidemiology of Hypertension and Associated Cardiovascular Complications

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 3012

The J-Shaped Association Between Serum Uric Acid Levels and Prevalence of Hypertension

**Shin Kawasoe** , Takuro Kubozono, Kagoshima Univ, Kagoshima, Japan; Satoko Ojima, Graduate Sch of Med, Kagoshima, Japan; Takeko Kawabata, Kagoshima Univ, Kagoshima, Japan; Hironori Miyahara, Kagoshima Kouseiren Health Care Ctr, Kagoshima, Japan; Shigeho Maenohara, Kagoshima Kouseiren Medical Health Care Ctr, Kagoshima, Japan; Mitsuru Ohishi, Kagoshima Univ, Kagoshima, Japan

11:30 AM

Board # 3013

Estimating Blood Pressure by Race/Ethnicity for Each State in The United States

**Catherine Johnson** , Univ of Washington, Seattle, WA; Simon Yadgir, Inst of Health, Seattle, WA; Alie Boon-Dooley, Univ of Washington, Seattle, WA; Gregory A Roth, Univ Washington, Seattle, WA

11:30 AM

Board # 3014

Target Blood Pressures Suggested by the 2017 American College of Cardiology/American Heart Association Hypertension Guidelines and the Systolic Blood Pressure Intervention Trial, Compared to Those of the Eighth Joint National Committee, are Associated With Lower Progression of Cardiovascular Imaging Markers of Disease in the Multi-Ethnic Study of Atherosclerosis

**Nitin Malik** , Bharath Ambale-Venkatesh, Mohammad R Ostovaneh, Johns Hopkins Hosp, Baltimore, MD; Colin Wu, Natl Insts of Health, Bethesda, MD; Joao A Lima, Johns Hopkins Hosp, Baltimore, MD

11:30 AM

Board # 3015

Rates and Correlates of Hypertension and Hypertension Awareness in a Cohort of Low Income Parents of School-Age Children in Worcester, MA

**Raghavendra Charan P Makam** , Univ of Massachusetts, Worcester, MA; Nishwant Swami, Univ of Massachusetts Medical Sch, Worcester, MA; Christine Frisard, Milagros C Rosal, Univ of Massachusetts, Worcester, MA

11:30 AM

Board # 3016

Diastolic Blood Pressure Levels and Mortality Among Older Women: Results From the Women's Health Initiative Long Life Study

**Sylvia Wassertheil-Smoller** , Albert Einstein Coll Med, Bronx, NY; Aileen McGinn, Albert Einstein Coll of Med, Bronx, NY; Bernhard Haring, Univ of Wurzburg, Wurzberg, Germany; Victor Kamensky, Albert Einstein Coll of Med, Bronx, NY; Michael Alderman, The Albert Einstein Coll of Med, Bronx, NY

11:30 AM

Board # 3017

Derivation And Validation Of An Integrated Risk Prediction Score System Based On Comprehensive Ambulatory Blood Pressure Parameters

**Hao-min Cheng** , Taipei Veterans General Hosp, Taipei, Taiwan; Tsung-Hsien Tasi, Acer Inc, Taipei, Taiwan; Shao-Yuan Chuang, Natl Health Res Insts, Zhunan, Miaoli, Taiwan; Liang-Kung Chen 100, Taipei Veterans General Hosp, Taipei, Taiwan; Chen-Huan Chen, Taipei Veterans General Hosp, Taipei

11:30 AM

Board # 3018

An Epidemiological Research of an Association Between Growth Hormone & Hypertension in a General Population

**Hideki Ohshima** , Hisashi Adachi, Mika Enomoto, Ako Fukami, Nakamura Sachiko, Yume Nohara, Akiko Sakaue, hitoshi hamamura, Kenta Toyomasu, Yoshihiro Fukumoto, Kurume Univ, Kurume, Japan

11:30 AM

Board # 3019

Legacy Effects of Baseline Blood Pressure 'Treatment Naivety' on All-cause and Cardiovascular Mortality in the Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

**Chau Ho** , Monique Bresliln, Menzies Inst for Medical Res, Hobart, Australia; Enayet Chowdhury, Sch of Public Health, Curtin Univ, Perth, Australia; Jenny Doust, Ctr for Res in Evidence Based Practice, Bond Univ, Gold Coast, Australia; Christopher Michael Reid, Monash Univ, Melbourne, Australia; Barry R Davis, Univ of Texas Sch Pub Hlth, Sugar Land, TX; Lara M Simpson, Univ Texas Sch Public Health, Houston, TX; Mark Raymond Nelson Jr., Univ of Tasmania, Hobart Tas Tas, Australia

11:30 AM

Board # 3020

Antihypertensive Medication Patterns in a Cohort of 164,805 Patients With Hypertension Between 2008-2017

**Tiffany Luong** , Rong Wei, Jaejin An, Lei Qian, Kaiser Permanente, Pasadena, CA; Paul Muntner, Univ of Alabama at Birmingham, Birmingham, AL; Jeff Brettler, Kaiser Permanente, Los Angeles, CA; Marc Jaffe, Resolve to Save Lives, New York City, NY; Kristi Reynolds, Kaiser Permanente, Pasadena, CA

11:30 AM

Poster Professor

Yuichiro Yano, Durham, NC

# Abstract Poster Session

## GE.APS.03 - Gene Expression and Cardiovascular Phenotypes

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 1123

**Absence of Thoracic Aortic Disease In** ACTA2R149C/+ **Mice is Associated With Defective Release of Mutant Smooth Muscle α-actin From the Chaperonin Complex**

**Dianna M Milewicz** , Jiyuan Chen, Kaveeta Kaw, Univ of Texas Health Science, Houston, TX; Abhijnan Chattopadhyay, UTHealth, Houston, TX; Xue Yan Duan, Univ of Texas Health Science, Houston, TX; Zhen Zhou, UT Health Science Ctr at Houston, Houston, TX; Callie Kwartler, UTHSC-Houston, Houston, TX; Kathleen Trybus, James Stull, Univ of Vermont, Burlington, VT; Kristine Kamm, UT Southwestern Medical Ctr, Dallas, TX; Shuangtao Ma, Michigan State Univ, East Lansing, MI

11:30 AM

Board # 1124

**Cardiac K** ATP **Subunit Expression is Regulated by Cholesterol and SREBP Signaling**

Robert Geiger, Naheed Fatima, **Thomas P Flagg** , USUHS, Bethesda, MD

11:30 AM

Board # 1125

The Biophysical Consequences of Thin Filament Hypertrophic Cardiomyopathy Mutations

**Giuliana Repetti** , Harvard Medical Sch, Boston, MA; Christopher Toepfer, HMS, Brookline, MA; Amanda Garfinkel, Harvard Medical Sch, Westfield, NJ; Victor Bellini, Kallyandra Padilha, Jon Wilcox, Gabriela Venturini, Harvard Medical Sch, Boston, MA; Jonathan Seidman, Christine E Seidman, Harvard Medical Ctr, Boston, MA

11:30 AM

Board # 1127

microRNA-448 is Causes Cardiac Sodium Channel Downregulation During Ischemia

**Gyeoung-Jin Kang** , An Xie, Hong Liu, Samuel C Dudley Jr., Univ of Minnesota, Minneapolis, MN

11:30 AM

Board # 1128

A Detrimental Genetic Environment Resulting in Extreme Lipoprotein (a) Levels and Premature C H D in a French Family

**Valentin Blanchard** , Gilles Lambert, Lab Inserm UMR DéTROI, Sainte Clotilde, Réunion

11:30 AM

Board # 1129

**Association of** Piezo1 **Variants With Hypertension in UK Biobank Participants**

Chew Cheng, Vijayalakshmi Deivasikamani, David J Beech, **Piruthivi Sukumar** , Univ of Leeds, Leeds, United Kingdom

11:30 AM

Board # 1130

Loss of Pkm2 Alters Myocardial Glucose Levels Before and After Infarction

**Allison L Williams** , Univ of Hawaii, Honolulu, HI; Lu Wang, Univ of Hawaii Cancer Ctr, Honolulu, HI; Katie Lee, Abigail Avelar, Univ of Hawaii, Honolulu, HI; Guoxiang Xie, Wei Jia, Univ of Hawaii Cancer Ctr, Honolulu, HI; Ralph V Shohet, Univ of Hawaii, Honolulu, HI

11:30 AM

Board # 1131

Disease-Associated Lamin a Variants Form Nuclear Aggregates With WT Using a Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Overexpression Model

**Corey L Anderson** , Emma R Langer, Seamus F McWilliams, Igor Bereslavskyy, Univ of Wisconsin-Madison, Madison, WI; Timothy J Kamp, U of Wisconsin-Madison, Madison, WI; Lee L Eckhardt, Univ of Wisconsin-Madison, Madison, WI

11:30 AM

Board # 1132

Lgals3: A Possible Modulator for Arrhythmogenic Cardiomyopathy?

**Giorgia Beffagna** , Univ of Padua, Padua, Italy; Cason Marco, Rudy Celeghin, Univ of Padua Medical Sch, Padova, Italy; Andrea Vettori, Univ of Verona, Verona, Italy; Mila Della Barbera, Univ of Padua Medical Sch, Padova, Italy; Cristina Basso, Univ of Padua, Padova, Italy; Gaetano Thiene, Univ of Padua Medical Sch, Padova, Italy; Natascia Tiso, Univ of Padova, Padova, Italy; Kalliopi Pilichou, Univ of Padua, Padua, Italy

11:30 AM

Board # 1133

Transcriptomic Heterogeneity of the Endothelium After Balloon Angioplasty and Stent Implantation on a Single Cell Level

**Anne Cornelissen** , Liang Guo, CVPath Inst, Gaithersburg, MD; Michael C. Kelly, Frederick Natl Lab for Cancer Res, Bethesda, MD; Atsushi Sakamoto, Salomé Kuntz, Hiroyuki Jinnouchi, Yu Sato, Frank D Kolodgie, Dipti Surve, Maria E Romero, Renu Virmani, Aloke V Finn, CVPath Inst, Gaithersburg, MD

11:30 AM

Board # 1134

Comprehensive Analysis of Aging-Related microRNAs and mRNAs Within the Human Heart and Blood

**Jinyang Zhao** , Qian Fan, Beijing An Zhen Hosp, Beijing, China

11:30 AM

Board # 1135

Dual Microrna-Targeting Rescues the Impaired Mitochondrial Unfolded Protein Response in Heart Failure

Marco Morelli, AECOM, New York, NY; Xujun Wang, Einstein-Montefiore, Bronx, NY; Alessandro Matarese, Colli Hosp, Naples, Italy; Christopher Chavez, Albert Einstein Coll of Med - Montefiore Univ Hosp, New York, NY; **Gaetano Santulli** , Albert Einstein Coll of Med, New York, NY

# Abstract Poster Session

## HF.APS.36 - Hemodynamics and Functional Capacity in Heart Failure

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2212

Upright Exercise Hemodynamic Profiles Effectively Risk Stratify Patients With Heart Failure With Preserved Ejection Fraction and Elevated Resting Filling Pressures

**John A Sbarbaro** , Kathryn Hardin, Robyn Farrell, Mark Schoenike, Thomas Cunningham, Liana Brooks, Mayooran Namasivayam, Emily Zern, Emily Lau, Massachusetts General Hosp, Boston, MA; Shawn Li, Massachussetts General Hosp, Boston, MA; Matthew G Nayor, Ravi V Shah, Massachusetts General Hosp, Boston, MA; Jennifer E Ho, Massachusetts General Hosp, Newton, MA; Rajeev Malhotra, Gregory Lewis, Massachusetts General Hosp, Boston, MA

11:30 AM

Board # 2213

Clinical Implications of Hepatic Hemodynamic Evaluation by Ultrasonography in Patients With Heart Failure

**Satoshi Abe** , Fukusima Medical Univ, Fukushima, Japan; Akiomi Yoshihisa, Yasuhiro Ichijo, Fukushima Medical Univ, Fukushima, Japan; Yusuke Kimishima, Fukushima Medical Univ, Fukushima City, Japan; Yuki Kanno, Tetsuro Yokokawa, Tomofumi Misaka, Takamasa Sato, Masayoshi Oikawa, ATSUSHI KOBAYASHI, Fukushima Medical Univ, Fukushima, Japan; Takayoshi Yamaki, Fukushima Medical Univ, Fukushina, Japan; Hiroyuki Kunii, Fukusima Medical Univ, Fukushima, Japan; Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

11:30 AM

Board # 2214

Exercise Capacity is Associated With Cerebral White Matter Hyperintensity in Frail Elderly Patients With Heart Failure

**Akihiro Hirashiki** , Atsuya Shimizu, Kazuhiro Kawashima, Kenichiro Nomoto, Natl Ctr for Geriatrics and Gerontology, Obu, Japan; Manabu Kokubo, Natl Ctr for Geriatrics and Gerontology, Ohbu, Japan; Sakurai Takashi, Hidenori Arai, Natl Ctr for Geriatrics and Gerontology, Obu, Japan

11:30 AM

Board # 2215

Clinical Implications of Intrarenal Hemodynamic Evaluation by Ultrasonography in Patients With Heart Failure

**Tomofumi Misaka** , Akiomi Yoshihisa, Yasuhiro Ichijo, Yusuke Kimishima, Yuki Kanno, Tetsuro Yokokawa, Satoshi Abe, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

11:30 AM

Board # 2216

Prognostic Assessment of the IABP-SHOCK II Risk Score in a Contemporary North American Population From the Critical Care Cardiology Trials Network Registry

**Carlos L Alviar** , New York Univ, New York, NY; Erin A Bohula, Brigham and Womens Hosp, Boston, MA; Vivian M Baird-Zars, Brigham and Women's Hosp and Harvard Medical Sch, Boston, MA; Jason N Katz, Univ of North Carolina, Chapel Hill, NC; Sean Van Diepen, Univ of Alberta, Edmonton, AB, Canada; David A Morrow, Brigham and Women's Hosp, Boston, MA; on behalf of the CCCTN Investigators

11:30 AM

Board # 2217

Post-Exercise Oxygen Uptake Recovery Kinetics Are Associated With Cardiac Performance and Outcomes in Suspected Heart Failure With Preserved Ejection Fraction

**Robyn M Farrell** , John Sbarbaro, Kathryn Hardin, Melissa Tanguay, Massachusetts General Hosp, Boston, MA; Jasmine Blodgett, Mark Schoenike, Mass General Hosp, Boston, MA; Thomas Cunningham, Cole S Bailey, Luke Wooster, Massachusetts General Hosp, Boston, MA; Emily Lau, Jamaica Plain, MA; Mayooran Namasivayam, Massachusetts General Hosp, Boston, MA; Ravi V Shah, Massachusetts General Hosp, Boston, MA, Newburyport, MA; Matthew G Nayor, Massachusetts General Hosp, Boston, MA; Jennifer E Ho, Massachusetts General Hosp, Newton, MA; Rajeev Malhotra, Gregory Lewis, Massachusetts General Hosp, Boston, MA

11:30 AM

Board # 2218

Arterial Pressure Volume Index and Arterial Velocity Pulse Index for Heart Failure With Preserved Ejection Fraction in Hypertensive Patients

**Jindong Wan** , Sen Liu, Yi Yang, Dan Wang, Fei Ran, Siwei Xia, Peng Zhou, Peijian Wang, Dept of Cardiology, Chengdu, China

11:30 AM

Board # 2219

Peripheral Venous Pressure Correlates With Central Venous Pressure In Heart Failure, Heart Transplant, And Left Ventricular Assist Device Patients

**Peter P Vlismas** , Elliot Wiesenfeld, Montefiore Medical Ctr, Bronx, NY; Kyung Taek Oh, Montefiore Medical Ctr/Albert Einstein Coll of Med, Bronx, NY; Sandhya Murthy, Montefiore Medical Ctr, Bronx, NY; Sasha VUKELIC, Montefiore Medical Centar AECOM, Bronx, NY; Omar Saeed, Snehal R Patel, Montefiore Medical Ctr, Bronx, NY; Jooyoung Shin, Montefiore, Bronx, NY; Ulrich P Jorde, Montefiore / Einstein, Bronx, NY; Daniel B Sims, Montefiore Medical Ctr, Bronx, NY

11:30 AM

Board # 2220

Cardiac Power Index Provides the Additional Long-term Prognostic Information to Adhere Risk Level in Patients Admitted for Acute Decompensated Heart Failure

**Takahisa Yamada** , Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masahiro Seo, Osaka General Medical Ctr, Osaka City, Japan; Jun Nakamura, Makoto Abe, Kyoko Yamamoto, Kiyomi Kayama, Osaka General Medical Ctr, Osaka, Japan; Masatsugu Kawahira, Osaka General Medical Ctr, Oosaka, Japan; Kazuya Tanabe, Osaka General Medical Ctr, Osaka, NY; Yuto Tamura, Takeshi Fujita, Masatake Fukunami, Osaka General Medical Ctr, Osaka, Japan

11:30 AM

Board # 2221

Long-term Prognostic Value of Acute Hemodynamic Index in Acute Decompensated Heart Failure Patients With and Without Reduced Left Ventricular Ejection Fraction

**Takahisa Yamada** , Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masahiro Seo, Osaka General Medical Ctr, Osaka City, Japan; Jun Nakamura, Makoto Abe, Kyoko Yamamoto, Kiyomi Kayama, Osaka General Medical Ctr, Osaka, Japan; Masatsugu Kawahira, Osaka General Medical Ctr, Oosaka, Japan; Kazuya Tanabe, Osaka General Medical Ctr, Osaka, NY; Yuto Tamura, Takeshi Fujita, Masatake Fukunami, Osaka General Medical Ctr, Osaka, Japan

11:30 AM

Poster Professor

Edward K Kasper, Baltimore, MD

# Abstract Poster Session

## HF.APS.35 - Hemodynamics in Heart Failure

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2202

Atrio-ventricular Synchronicity Improves Fontan Hemodynamics

**Hirofumi Saiki** , Iwate Medical Univ, Morioka, Iwate, Japan; Seiko Kuwata, kitasato university, kanagawa, Japan; Manabu Takanashi, Kitasato Univ Hosp, Sagamihara, Japan; Satoshi Masutani, SAITAMA MEDICAL UNIVERSITY, Saitama-ken, Japan; Hideaki Senzaki, Kitasato Univ, Kanagawa, Japan

11:30 AM

Board # 2203

Blood Pressure Responses During Exercise Are Associated With Exertional Wedge Pressure and Stroke Volume Augmentation in Heart Failure With Preserved Ejection Fraction

**Mayooran Namasivayam** , Emily S Lau, Mark W Schoenike, Kathryn M Hardin, John A Sbarbaro, Thomas F Cunningham, Robyn M Farrell, Matthew G Nayor, Ravi V Shah, Jennifer E Ho, Rajeev Malhotra, Gregory D Lewis, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA

11:30 AM

Board # 2204

Left Atrial Mechanics in Heart Failure Before and After Decongestive Therapy: Insights From Deformation Imaging With Invasive Hemodynamics

**Sébastien Deferm** , Pieter Martens, Philippe B Bertrand, Ziekenhuis Oost-Limburg, Genk, Belgium; Frederik Hendrik Verbrugge, Ziekenhuis Oost-Limburg Genk, Genk, Belgium; Jeroen Dauw, David Verhaert, Matthias Dupont, Pieter Vandervoort, Wilfried Mullens, Ziekenhuis Oost-Limburg, Genk, Belgium

11:30 AM

Board # 2205

Hemodynamic Response to Rapid Saline Loading in Heart Transplant Recipients

**Monika Kodeboina** , Giuseppe Di Gioia, Iginio Colaiori, Frederik Van Durme, jeroen Sonck, OLV Cardiovascular Reasearch Ctr, Aalst, Belgium; Carlos Collet, OLV Aalst, Aalst, Belgium; Bernard De Bruyne, Cardiovascular Ctr Aalst, Aalst, Belgium; Jozef Bartunek, Marc Vanderheyden, Cardiovascular Ctr, Aalst, Belgium

11:30 AM

Board # 2206

Interplay of Different Cell Death Mechanisms in Explanted Human Heart

**Hemang Patel** , Ascension St. John Hosp, Detroit, MI; Giovanni Corsetti, Univ of Brescia, Brescia, Italy; Carol Chen-Scarabelli, VA Healthcare System, Glen Allen, VA; Kellie Brue, Ascension St. John Hosp, Detroit, MI; Giuseppe Faggian, Univ of Verona, Verona, Italy; Louis Saravolatz, Ascension St. John Hosp, Detroit, MI; Tiziano M Scarabelli, Virginia Commonwealth Univ, Richmond, VA

11:30 AM

Board # 2207

Hemodynamic Determinants of Tricuspid Annular Pulmonary Systolic Excursion (tapse)/ Systolic Pulmonary Arterial Pressure (spap) Ratio in Heart Failure With Reduced Ejection Fraction

**Francesco Bandera** , Greta Ghizzardi, Mauro Agnifili, Samuele Pizzocri, IRCCS Policlinico San Donato, Milano, Italy; Sara Boveri, IRCCS Policlinico San Donato, San Donato Milanese, Italy; Eleonora Alfonzetti, Massimo Saviano, Giacomo D'Alesio, Francesco Badogni, Marco Guazzi, IRCCS Policlinico San Donato, Milano, Italy

11:30 AM

Board # 2208

The Cardiopulmonary Vicious Cycle, the Immediate Effect of the Respiratory Effort on Pulmonary Capillary Wedge Pressure

Noa Markovitch, Anna Faingersh-Klebanov, Technion - Israel Inst of Technology, Haifa, Israel; Shmuel Rispler, Yair Feld, Eugenia Nikolsky, Yuval Cohen, Sergey Yalonetsky, Rambam Health Care Campus, Haifa, Israel; Ariel Roguin, Hillel Yafe Medical Ctr, Hadera, Israel; Arthur Kerner, Rambam Medical Ctr, Haifa, Israel; **Amir Landesberg** , Technion - Israel Inst of Technology, Haifa, Israel

11:30 AM

Board # 2209

Simultaneous Measurement of Lung Diffusion and Pulmonary Hemodynamics During Exercise in Heart Failure With Preserved Ejection Fraction

**Caitlin C Jorgenson** , Glenn M Stewart, Barry A Borlaug, Bruce D Johnson, Mayo Clinic, Rochester, MN

11:30 AM

Board # 2210

Maladaptive Hemodynamic Responses to Sympathetic Activation Play a Pivotal Role in the Pathogenesis of Acute Decompensated Heart Failure

**Takafumi Sakamoto** , Kyushu Univ Hosp, Fukuoka, Japan; Keita Saku, Kenji Sunagawa, Hiroyuki Tsutsui, Kyushu Univ, Fukuoka, Japan

11:30 AM

Board # 2211

Tissue is the Issue: Endomyocardial Biopsy Characterization of Heart Failure With Preserved Ejection Fraction and Cardiac Amyloidosis

**Virginia Shalkey Hahn** , Johns Hopkins Univ, Baltimore, MD; Wendy Ying, Johns Hopkins Univ Sch of Med, Baltimore, MD; Yizhen Joan Lee, Johns Hopkins Univ, Baltimore, MD; Lisa R Yanek, Johns Hopkins Medical Insts, Baltimore, MD; Dhananjay Vaidya, Johns Hopkins Univ, Baltimore, MD; Vinita Subramanya, Emory Rollins SPH, Atlanta, GA; Sarah Riley, Kira Perzel Mandell, Marc Kenneth Halushka, Avi Z Rosenberg, Johns Hopkins Univ, Baltimore, MD; Daniel P Judge, Medical Univ South Carolina, Charleston, SC; David Alan Kass, Johns Hopkins Hosp, Baltimore, MD; Stuart D Russell, Duke Univ Medical Ctr, Raleigh, NC; Kavita Sharma, Johns Hopkins Univ SOM, Baltimore, MD

# Abstract Poster Session

## IN.APS.14 - Interventional Complications: Did We Really Cause This?

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 4237

Intraprocedural Stent Thrombosis: A Case Report With Review of Literature

**Anubhav Jain** , Ascension Providence Rochester Hosp/Wayne State Univ, Rochester Hills, MI; Ankita Aggarwal, Ascension Providence Rochester Hosp/Wayne State Univ, Auburn Hills, MI; Nitya Beriwal, Lady Hardinge Medical Coll, New Delhi, India

11:30 AM

Board # 4238

Aspergillus Infective Endocarditis Presenting as Lower Limb Ischemia in Lung Transplant Patient With Cystic Fibrosis

**Timothy Pow** , Loyola Univ Medical Ctr, Maywood, IL; Lara Bakhos, Loyola Univ Medical Ctr, Chicago, IL; Shruti Patel, Kumaran M Mudaliar, Loyola Univ Medical Ctr, Maywood, IL

11:30 AM

Board # 4239

Coronary Graft Perforation Complicating Percutaneous Coronary Intervention With Excimer Laser Coronary Atherectomy in a Patient With Saphenous Vein Graft Occlusion

**Yuvraj S Chowdhury** , SUNY Downstate Medical Ctr, Brooklyn, NY; Mrinali Shetty, Univ of Chicago (Northshore), Evanston, IL; Radhika-Alicia Patel, Cardio Metabolic Inst, Somerset, NJ; Pratik Patel, Robert Wood Johnson Univ Hosp, New Brunswick, NJ

11:30 AM

Board # 4240

Crucial Post Operative Thrombocytopenia-Acute Graft Thrombosis Secondary to Heparin Induced Thrombocytopenia

**Ayesha Shaik** , UConn Health, Farmington, CT; Sonal Pruthi, Hartford Hosp, Hartford, CT; Ayesha Azmeen, UConn Health, Farmington, CT; Surya Teja Chaturvedula, Uconn Health Ctr, Newington, CT; Talhat Azemi, Hartford Hosp, Hartford, CT

11:30 AM

Board # 4241

A Massive Prosthetic Aortic Valve Dilemma

**Minakshi Biswas** , Zachary Graham, Luisa Mestroni, Univ of Colorado, Aurora, CO

11:30 AM

Board # 4242

Type a Acute Aortic Syndrome Complicated With Cardiac Tamponade

**Chiehju Chao** , William K Freeman, Mayo Clinic Arizona, Phoenix, AZ

11:30 AM

Board # 4243

Atrioventricular Conduction Disease Associated With Ticagrelor Use in Acute Coronary Syndrome

**Karim Abdur Rehman** , Cleveland Clinic Fndn, Cleveland, OH; Haris Riaz, Mina K Chung, Grant Reed, Cleveland Clinic, Cleveland, OH

11:30 AM

Board # 4244

A Case of Epinephrine Induced Takotsubo Cardiomyopathy

**Golda Harvatin** , Loma Linda Univ Medical Ctr, Loma Linda, CA

11:30 AM

Board # 4245

Spontaneous Coronary Artery Dissection Following Exposure to Triptan

**Jafar Alzubi** , Cleveland Clinic Akron General, Akron, OH; Ahmad Jabri, Akron, OH; David Hedrick, Cleveland Clinic Akron General, Akron, OH

11:30 AM

Board # 4246

Superior Vena Cava-Right Atrial Junction Endocarditis in HIV Positive Patient With Active IV Drug Use

**Usama Talib** , Sneha Lakshman, Sohaib A Ansari, Yusef A Esparza Monzavi, Patrick L Gordan, Northshore Medical Ctr, Salem, MA

11:30 AM

Board # 4247

Global DNA Hypomethylation and Reduced Levels of Inflammatory Mediators Are Associated to High Air Pollution in a Prospective Cohort of Healthy Subjects

**Fernando Lanas** , Montserrat A. Hevia, Isis Paez, Katherine Andara, Nicolás Saavedra, Kathleen Saavedra, Pamela Serón, Luis A. Salazar, Univ de La Frontera, Temuco, Chile

11:30 AM

Board # 4248

Recurrent Appropriate Shocks in a Patient With Twiddler's Syndrome

**Michael P Cinelli** , Samer Saouma, Harout Yacoub, Farshid Daneshvar, Soad Bekheit, Staten Island Univ Hosp, Staten Island, NY

# Abstract Poster Session

## EA.APS.29 - Issues in Anticoagulation Therapy for Arrhythmias

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2063

Clinical Practice and Outcomes With Cardioversion in the Non-vitamin K Oral Anticoagulant Era: Insights From the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II

**Kyle Geurink** , Dajuanicia N Simon, Duke Univ, Durham, NC; Karen S Pieper, Duke Clinical Res Inst, Durham, NC; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; Peter R Kowey, Lankenau Medical Ctr, Wynnewood, PA; James A Reiffel, Columbia Univ, Jupiter, FL; Daniel E Singer, Massachusetts General Hosp, Boston, MA; James V Freeman, Yale Univ Sch of Med, New Haven, CT; Bernard J Gersh, Mayo Clinic, Wilson, WY; Kenneth Mahaffey, Stanford Univ, Stanford, CA; Elaine Hylek, Boston Univ, Boston, MA; Gerald V Naccarelli, Penn State HVI, Hershey, PA; Michael D Ezekowitz, Medical Coll at Thomas Jefferson, Villanova, PA; Jonathan P Piccini, Duke Univ Medical Ctr, Durham, NC; Eric D Peterson, Duke Clinical Res Inst, Chapel Hill, NC; Sean Pokorney, Duke Univ, Raleigh, NC

11:30 AM

Board # 2064

A Novel Simple Risk Score for the Prediction of All Cause Death in Atrial Fibrillation Patients With Direct Oral Anticoagulants

**Masato Kawasaki** , Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masahiro Seo, Osaka General Medical Ctr, Osaka City, Japan; Makoto Abe, Jun Nakamura, Kyoko Yamamoto, Kiyomi Kayama, Osaka General Medical Ctr, Osaka, Japan; Masatsugu Kawahira, Osaka General Medical Ctr, Oosaka, Japan; Kazuya Tanabe, Osaka General Medical Ctr, Osaka, NY

11:30 AM

Board # 2065

Adherence of Dabigatran and the Influence of Dabigatran-induced Gastrointestinal Discomfort in the Real World Practice

**Seongwook Han** , Jongmin Hwang, Keimyung Univ Dongsan Hosp, Daegu, Korea, Republic of; So Ryoung Lee, Seoul Natl Univ Hosp, Seoul; Eue-Keun Choi, Seoul Natl Univ Hosp, Seoul, Korea, Republic of; Hyoung-Seob Park, Keimyung Univ, Dongsan Medica, Daegu, Korea, Republic of; Young Soo Lee, Daegu Catholic Univ Medical Ctr, Daegu, Korea, Republic of; Jin Hee Ahn, Pusan Natl Univ Hosp, Busan, Korea, Republic of; Jong-il Choi, Korea Univ Hosp, Seoul; Dong Gu Shin, Yeungnam Univ Hosp, Daegu, Korea, Republic of; Dae-Kyeong Kim, Inje Univ Busan Paik Hostpital, Busan, Korea, Republic of; Jong Sung Park, Dong-A Univ Medical Ctr, Busan, Korea, Republic of; Ki Won Hwang, Pusan Natl Univ Yangsan Hosp, Gyeongsangnam-do, Korea, Republic of; Tae-Joon Cha, Kosin Univ Gospel Hosp, Busan, Korea, Republic of

11:30 AM

Board # 2066

Impact of Renal Function on Bleeding Risk in Patients With Non-Valvular Atrial Fibrillation Treated With Direct Oral Anticoagulants

**Tomoaki Kobayashi** , Yohei Sotomi, Akio Hirata, Atsushi Hirayama, Yoshiharu Higuchi, Osaka Police Hosp, Osaka, Japan

11:30 AM

Board # 2067

Real World Experience With Direct Oral Anticoagulants After Watchman Implantation

Ethan Fry, Baylor Scott and White, Temple, TX; **Harini Bollempali** , Baylor Scott and White Medical Ctr, Round Rock, TX; Keith Suarez, Jeffrey Michel, Baylor Scott and White, Temple, TX; Javier E Banchs, Baylor Scott & White Health - Texas A & M, Temple, TX

11:30 AM

Board # 2068

Effectiveness and Safety of Non-vitamin K Antagonist Oral Anticoagulants Among Nonvalvular Atrial Fibrillation Patients With Polypharmacy Use

Gregory Y.H. Lip, Liverpool Ctr for Cardiovascular Science, Univ of Liverpool and Liverpool Heart & Chest Hosp, Liverpool, United Kingdom; Allison Keshishian, STATinMED Res and New York City Coll of Technology, Ann Arbor, MI; Amiee Kang, Amol Dhamane, Bristol-Myers Squibb Company, Lawrenceville, NJ; Xuemei Luo, Pfizer, Inc., Groton, CT; Christian Klem, **Lisa Rosenblatt** , Bristol-Myers Squibb Company, Lawrenceville, NJ; Jack Mardekian, Pfizer, Inc, New York, NY; Jenny Jiang, Bristol-Myers Squibb Company, Lawrenceville, NJ; Huseyin Yuce, New York City Coll of Technology, New York, NY; Steve Deitelzweig, Ochsner Clinic Fndn, New Orleans, LA

11:30 AM

Board # 2069

Role of Anticoagulation in the Management of Atrial Fibrillation Post Catheter Ablation in Patients With Moderate Chadsvasc

**Aneesh Dhore-Patil** , Muhammad Umer Butt, Case Western Reserve Univ-MetroHealth Medical Ctr, Cleveland, OH; Soufian Almahameed, Metrohealth Medical Ctr, Roanoke, VA; Amit Arbune, Yale Univ Sch of Med, New Haven, CT; David Hoffman, St Elizabeth Mercy Health, Youngstown, OH; Ohad Ziv, Case Western Reserve Univ-MetroHealth Medical Ctr, Cleveland, OH

11:30 AM

Board # 2070

Uninterrupted Apixaban Increases Intraprocedural Heparin Requirement During Catheter Ablation of Atrial Fibrillation

**Peter Hyson** , Univ of Colorado Sch of Med, Aurora, CO; Matthew Zipse, Univ of Colorado Denver, Denver, CO; Amanda Charlton, Univ of Colorado Skaggs Sch of Pharmacy, Aurora, CO; Toby Trujillo, Univ of Colorado, Aurora, CO; Courtney Shakowski, Univ of Colorado Hosp, Denver, CO; Robert Lee Page II, Univ of Colorado, Aurora, CO; Blake Fleeman, Nicholas Mantini, Brian Miller, Shu Chang, Univ of Colorado Sch of Med, Aurora, CO; Ryan G Aleong, Univ Colorado, Aurora, CO; Ryan Borne, Univ of Colorado, Aurora, CO; Duy Nguyen, Univ of Colorado Sch of Med, Aurora, CO; Michael Rosenberg, Univ of Colorado Sch of Med, Denver, CO; Amneet Sandhu, Univ of Colorado, Denver, CO; William Sauer, Joseph Schuller, Christine Tompkins, Univ of Colorado, Aurora, CO; Paul D Varosy, VAECHCS - Univ of CO, Denver, CO; Wendy S Tzou, Univ of Colorado, Aurora, CO; Alexis Z Tumolo, Univ of Colorado Hosp, Denver, CO

11:30 AM

Board # 2071

Efficacy and Risk of Therapy With the Vitamin K Antagonist Phenprocoumone Compared to Direct Oral Anticoagulants in Catheter Ablation of Atrial Fibrillation

**Diona Gjermeni** , Uniklinik Freiburg, Freiburg, Germany; Volker Kuehlkamp, Herz-Zentrum-Bodensee, Kreuzlingen, Germany

11:30 AM

Board # 2072

Risk Factors and Management of Left Atrial Appendage Thrombus (LAAT) Prior to Atrial Fibrillation Ablation

**Bishal Bhandari** , Southern Illinois Univ Sch of Med, Springfield, IL; Manjari Regmi, Southern Illinois Univ, Springfield, IL; Abdisamad Ibrahim, Southern Illinois Univ Sch of Med, Springfield, IL; Michael Buhnerkempe, SIU Sch of Med, Springfield, IL; Mohamed Labedi, Southern Illinois Univ Sch of Med, Springfield, IL

11:30 AM

Board # 2073

Evaluating The Rate Of Coumadin Prescription In The Era Of Direct Oral Anticoagulants

**Yana Shamiss** , Pouria Alipour, Zahra Azizi, Southlake Regional Health Ctr, Newmarket, ON, Canada; Hadi Tohidi, Southlake Regional Helath Ctr, Newmarket, ON, Canada; Claire Jansen, Alexander Shusterman, Nina Varah, Sarah Donegan, Sereena Nath, Alona Avoulov, Sara Tamjidi, Hodaya Lightstone, Southlake Regional Health Ctr, Newmarket, ON, Canada; Stacey Morris, Southlake Regional Health Ctr, Thornhill, ON, Canada; Yaariv Khaykin, Southlake Regional Health Ctr, Richmond Hill, ON, Canada

# Abstract Poster Session

## AT.APS.18 - Modifiers and Effectors Downstream of Low-Density-Lipoprotein Cholesterol

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Poster Professor

Marina Cuchel, Narberth, PA

11:30 AM

Board # 1019

Daunorubicin Associated With Lipid Nanoparticles Reduces Inflammation and Aortic Lesions in an Atherosclerosis Rabbit Model

**Camila I Albuquerque** , Elaine R Tavares, Maria Carolina Guido, Insto de Coracao, HCFMUSP, Univ de Sao Paulo, Sao Paulo, Brazil; Natalia M Lopes, Insto de Coracao, HCFMUSP, Univ de Sao Paulo, São Paulo, Brazil; Roberta Vanalli Baroni, Insto de Coracao, HCFMUSP, Univ de Sao Paulo, Sao Paulo, Brazil; Leonardo Jensen, Insto de Coracao, HCFMUSP, Univ de Sao Paulo, São Paulo, Brazil; Bruna M o Araujo Silva, Roberto Kalil, Thauany M Tavoni, Raul C Maranhao, Insto de Coracao, HCFMUSP, Univ de Sao Paulo, Sao Paulo, Brazil

11:30 AM

Board # 1020

Proprotein Convertase Subtilisin/Kexin Type 9 Deficiency Leads To More Severe Anemia In A Murine Model Of Sickle Cell Disease

**Jessica Venugopal** , Jintao Wang, Chiao Guo, Univ of Michigan, Ann Arbor, MI; Daniel Eitzman, Univ Mich Hlth Sys, Ann Arbor, MI

11:30 AM

Board # 1021

Beta-Carotene Conversion to Vitamin A Delays Atherosclerosis Progression by Reducing VLDL Secretion

**Jaume Amengual** , Univ of Illinois, Urbana, IL

11:30 AM

Board # 1022

The Ldl-receptor Relative Lr11 is an Autonomous Regulator of White-to-beige Trans-differentiation in Polymer-scaffold 3d-cultured Adipocytes

**Meizi Jiang** , Toho Univ Sakura Medical Ctr, Sakura, Japan; Tatsuro Kanaki, Nissan Chemical Industries, Ltd., Tokyo, Japan; Hayashi Akiteru, Toho Univ Sakura Medical Ctr, sakura, Japan; Hiroyuki Ebinuma, Tsukuba Res Inst, Sekisui Medical Co. Ltd., Ibaraki, Japan; Wolfgang J Schneider, Medical Univ of Vienna, Max F. Perutz Labs, Vienna, Austria; Hideaki Bujo, Toho Univ Sakura Medical Ctr, Sakura, Japan

11:30 AM

Board # 1023

An Electronegative LDL Induced by Atherogenic Diet Disrupts Cholesterol Homeostasis and Activates Pro-Inflammatory Pathways

**Po-Yuan Chang** , Natl Taiwan Univ Hosp, Taipei City, Taiwan; Jou-Hsiang Pai, Yu-Sheng Lai, Shao-Chun Lu, Natl Taiwan Univ Coll of Med, Taipei City, Taiwan

11:30 AM

Board # 1025

A Novel Role of Apolipoprotein E Glycosylation in Atherogenic L5 Low-Density Lipoprotein

**Liang-Yin Ke** , Kaohsiung Medical Univ, Kaohsiung, Taiwan; Hua-Chen Chan, Kaohsiung Medical Univ Hospit, Kaohsiung, Taiwan; Chih-Chieh Chen, Kaohsiung Medical Univ, Kaohsiung, Taiwan; Chu-Huang Chen, Texas Heart Inst, Houston, TX

11:30 AM

Board # 1026

Type 2 Cell Low Density Lipoprotein Receptor-Related Protein 1 Regulates Surfactant Lipid, Pulmonary Function, and Extrapulmonary Metabolism

**Christina Agudelo** , Saioa Mendizuri, SUNY Donwstate Medical Ctr, Brooklyn, NY; Estela Area-Gomez, SUNY Donwstate Medical Ctr, New York, NY; Yimeng Xu, Columbia Univ Medical Ctr, New York, NY; Patrick Geraghty, Abdoulaye Dabo, SUNY Donwstate Medical Ctr, Brooklyn, NY; Ira Goldberg, New York Univ Langone Medical Ctr, New York, NY; Robert Foronjy, Itsaso Garcia-Arcos, SUNY Donwstate Medical Ctr, Brooklyn, NY

11:30 AM

Board # 1027

Molecular Chaperones Facilitate the Pre-Secretory Degradation of Apolipoprotein B, the Major Proteinaceous Component in Chylomicrons and Very Low Density Lipoprotein Particles

**Deepa Kumari** , Jeffrey L. Brodsky, Univ of Pittsburgh, Pittsburgh, PA

11:30 AM

Board # 1028

Prognostic Impact of Lipoprotein(a) on Long-term Clinical Outcomes in Diabetic Patients on Statin Treatment After Percutaneous Coronary Intervention

**Norihito Takahashi** , Juntendo Univ, Bunkyo-ku, Tokyo, Japan; Tomotaka Dohi, Takehiro Funamizu, Juntendo Univ, Tokyo, Japan; Hirihisa Endo, Juntendo Univ, Bunkyo-ku, Tokyo, Japan; Hideki Wada, Juntendo Univ Shizuoka Hospit, Izunokuni Shizuoka, Japan; Shinichiro Doi, Juntendo Univ, Tokyo, Japan; Manabu Ogita, Juntendo Univ, Izunokuni, Japan; Hiroshi Iwata, Juntendo Univ, Tokyo, MA, Japan; Shinya Okazaki, Kikuo Isoda, Katsumi Miyauchi, Kazunori Shimada, Juntendo Univ, Tokyo, Japan

# Abstract Poster Session

## EA.APS.25 - New Insights into Atrial and Supraventricular Arrhythmias

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2020

Atrial Tachyarrhythmias in Adult Patients With Tetralogy of Fallot and Congenital Pulmonary Stenosis: Long Term Catheter Ablation Results and Rates of Recurrence

**Christopher S Grubb** , Columbia Univeristy Medical Ctr, New York, NY; Marlon S Rosenbaum, Columbia Univ, New York, NY; Hasan Garan, New York Presbyterian Medical Ctr, New York, NY; Angelo B Biviano, Columbia Univ Medical Ctr, New York, NY

11:30 AM

Board # 2021

A New Phenotype of Superior-type Fast-slow Atrioventricular Nodal Reentrant Tachycardia Mimicking the Slow-fast Type

**Yoshiaki Kaneko** , Tadashi Nakajima, Shuntaro Tamura, Hiroshi Hasegawa, Gunma Univ Graduate Sch of Med, Maebashi Gunma, Japan; Masahiko Kurabayashi, Gunma Univ Grad Sch of Med, Gunma, Japan

11:30 AM

Board # 2022

Electrophysiological Characteristics And Maldistribution Of Myocardial Sleeve In The Superior Vena Cava

**Toshio Kinoshita** , Hitomi Yuzawa, Ryo Wada, Kensuke Yano, Shintaro Yao, Katsuya Akitsu, Hideki Koike, Masaya Shinohara, Takeya Suzuki, Tadashi Fujino, Takanori Ikeda, Toho Univ Faculty of Med, Tokyo, Japan

11:30 AM

Board # 2023

Ends Only Ablation of the Cavo-Tricuspid Isthmus in Typical Atrial Flutter

**Lae-Young Jung** , Won-Sik Yun, Ja-Yeon Lee, Chonbuk Natl Univ Hosp, Jeon-Ju, Korea, Republic of

11:30 AM

Board # 2024

Efficacy of Self-reference Mapping Technique to Eliminate Non-pulmonary Vein Triggers Originated From Outside of Primordial Pulmonary Vein

**Yasuharu Matsunaga** , Yasuyuki Egami, Yutaka Matsuhiro, Hitoshi Nakamura, Koji Yasumoto, Osaka Rosai Hosp, Sakai, Japan; Akihiro Tanaka, Div of Cardiology, Sakai, Japan; Okamoto Naotaka, Osaka Rosai Hosp, Sakai, Japan; Daisuke Nakamura, Div of Cardiology, Sakai, Japan; Masamichi Yano, 3-1179, Sakai, Japan; Yamato Masaki, Ryu Shutta, Osaka Rosai Hosp, Sakai, Japan; Masami Nishino, Osaka Rosai Hosp, Sakai Osaka, Japan; Tanouchi Jun, Osaka Rosai Hosp, Sakai, Japan

11:30 AM

Board # 2025

CT-based Virtual Heart and 12-lead ECG-based Automated VT Localization Method Identify Ablation Targets in a Patient Undergoing Intramural Ablation—A Case Study

**Shijie Zhou** , Eric Sung, Johns Hopkins Univ, Baltimore, MD; Amir AbdelWahab, Qeii Health Sciences Ctr, Halifax, NS, Canada; Adityo Prakosa, Konstantinos Aronis, Johns Hopkins Univ, Baltimore, MD; Bohumil Milan Horacek, Dalhousie Univ, Halifax, NS, Canada; Ratika Parkash, Martin John Gardner, Chris Gray, Ciorsti Jean Macintyre, Jason Davis, John L Sapp, Qeii Health Sciences Ctr, Halifax, NS, Canada; Natalia Trayanova, Johns Hopkins Univ, Baltimore, MD

11:30 AM

Board # 2027

Atrial Fibrillation Ablation Outcome in Congenitally Corrected Transposition of Great Arteries

**Pooneh Nabavizadeh** , Univ of Cincinnati, Cincinnati, OH; Richard J Czosek, Cincinnati Childrens Hosp, Cincinnati, OH; Timothy K Knilans, Children's Hosp Medical Ctr, Cincinnati, OH; Mehran Attari, Mercy Heart Inst, Cincinnati, OH; Srinivas Rajsheker, Univ of Cincinnati, Cincinnati, OH; David Spar, Cincinnati Children's Medical Ctr, Cincinnati, OH

11:30 AM

Board # 2028

Rapid Cardioversion of Recent-Onset Atrial Fibrillation in the Emergency Department With Vernakalant: Insights From the Multinational Spectrum Registry

**Beate Ritz** , Correvio Intl, Geneva, Switzerland; Alfonso Martin, Univ Hosp Severo Ochoa and Univ AlfonsoX, Madrid, Madrid, Spain; José L Merino, La Paz Univ Hosp, Madrid, Spain; Johan-Emil Bager, Sahlgrenska Univ Hosp, Gothenburg, Sweden; Hans Domanovits, Medical Univ of Vienna, Vienna, Austria; Todd Juhlin, Skåne Univ Hosp, Malmo, Sweden; Samuel Levy, Cardiology, Marseille, France; W.Douglas Weaver, Correvio Intl, Geneva, Switzerland; Juha Hartikainen, Kuopio Univ Hosp, Kuopio, Finland; Jose Carbajosa Sr., General Univ Hosp of Alicante, Alicante, Spain

11:30 AM

Board # 2029

Episodes of Asymptomatic Atrial Fibrillation Patients With Heart Failure and ICD/CRT-D Based on Analysis Intracardiac Electrocardiograms

**Barbara Dominik** , Zorawski Wojciech, Univ of Zielona Góra, Zielona Gora, Poland; Ilona Kowalik, Inst of Cardiology, Warszawa, Poland; Adam Ciesielski, Univ of Zielona Góra, Zielona Gora, Poland; Przemyslaw Mitkowski, Medical Univ, Poznan, Poland

# Abstract Poster Session

## AC.APS.07 - Non Atherosclerotic Causes of Cardiovascular Compromise

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 4010

Young Female With Chest Pain: Going Beyond the Obvious

**Sebastian Gallo-Bernal** , Azucena Martinez Caballero, Juan Felipe Vásquez, Nicolas Isaza, Daniel Isaza, Claudia Jaimes, Fundacion Cardioinfantil- Cardiology Inst, Bogota, Colombia

11:30 AM

Board # 4011

Veno-Arterial Extracorporeal Membrane Oxygenation and Pulmonary Vasodilators, Bridge to Recovery in Fat Embolism-Induced Pulmonary Hypertension and Right Ventricular Failure

**Yinn Shaung Ooi** , Heriberto Enrique Matos Santana, Joanna M Joly, Univ of Alabama at Birmingham, Birmingham, AL

11:30 AM

Board # 4012

Two Big, Two Fail: Massive Ectasia of the Right Coronary Artery After Reimplantation From the Pulmonary Artery, and Giant Aneurysm of the Left Coronary Artery

**Nathan L Frogge** , Puja Kachroo, Washington Univ Sch of Med, St Louis, MO; Marc R Moon, Washington Univ Sch of Med, Saint Louis, MO; Amit P Amin, Washington Univ Cardiology, Saint Louis, MO; Philip M Barger, Kathryn J Lindley, Washington Univ Sch of Med, St Louis, MO

11:30 AM

Board # 4013

A Unique Presentation of Idiopathic Purulent Pericardial Effusion With Tamponade & Atrial Fibrillation

**Sarabjeet S Suri** , Karishma Kitchloo, AECOM- Montefiore Medical Ctr, Bronx, NY

11:30 AM

Board # 4014

A Unique Presentation of Sheehan's Syndrome With Acute Pericarditis

**Sarabjeet S Suri** , Lakshmi Priyanka Mahali, Colette Knight, AECOM- Montefiore Medical center, Bronx, NY

11:30 AM

Board # 4015

A Giant Coronary Artery Ectasia Successfully Managed With Coronary Artery Stenting

Asrar Ahmad, **Sohaib Sanan Roomi** , Waqas Ullah, Zain Ali, Abington Hosp-Jefferson Health, Abington, PA; Hafez Abdullah, Univ of South Dakota, sioux falls, SD; Mishal Shaukat, CMH Lahore Medical Coll, Lahore, Pakistan

11:30 AM

Board # 4016

A Young Man With Stemi: Diagnostic Evaluation of Myocardial Bridging

**Madeline K Mahowald** , Michel Corban, Abhiram Prasad, Mayo Clinic, Rochester, MN

11:30 AM

Board # 4017

Thrombocytopenia Triggering Troponinemia: A Therapeutic Travesty

**Yuvraj Chowdhury** , SUNY Downstate Medical Ctr, Brooklyn, NY; Mrinali Shetty, Univ of Chicago (Northshore), Evanston, IL; Avishkar Sabharwal, Saint Peter's Univ Hosp, New Brunswick, NJ

11:30 AM

Board # 4018

STEMI and Ventricular Tachycardia: A Unique Presentation of Fabry Disease

**Muhammad A Khan** , Eric Czajkowski, Sheraz Hussain, Tareq Al Saadi, Fatima M Kazi, Melanie Gordon VI, Advocate Christ Medical Ctr, Oak Lawn, IL

11:30 AM

Board # 4019

Pembrolizumab Induced Complete Heart Block Associated With Myocarditis

**Usama Talib** , Allisa Alpert, Tatyana Sycheva, Northshore Medical Ctr, Salem, MA

11:30 AM

Poster Professor

VALERIAN Fernandes, Charleston, SC

# Abstract Poster Session

## HF.APS.33 - Novel Biomarkers and Applications To A Heart Failure Diagnosis and Management

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2182

Biomarker Profile of Left Atrial Myopathy in Heart Failure With Preserved Ejection Fraction

**Ravi B Patel** , Northwestern Univ, Chicago, IL; Fawaz Alenezi, Duke Univ Medical Ctr, Durham, NC; Jie-Lena Sun, Duke Clinical Res Inst, Durham, NC; Brooke Alhanti, Duke Univ, Durham, NC; Muthiah Vaduganathan, Brigham and Women's Hosp, Boston, MA; Jae K Oh, Margaret M Redfield, Mayo Clinic, Rochester, MN; Javed Butler, Univ of Mississippi, Jackson, MS; Adrian F Hernandez, Duke Univ Sch of Med, Durham, NC; Eric Jose Velazquez, Yale Univ Sch of Med, New Haven, CT; Sanjiv J Shah, Northwestern Univ, Chicago, IL

11:30 AM

Board # 2183

Higher B-type Natriuretic Peptide Concentrations are Associated With Better Left Ventricular Function in The General Population: The Akershus Cardiac Examination 1950 Study

**Magnus Nakrem Lyngbakken** , Brede A Kvisvik, Akershus Univ Hosp, Lørenskog, Norway; Erika Nerdrum Aagaard, Akershus Univ Hosp, Lorenskog, Norway; Trygve Berge, Bærum Hosp, Vestre Viken Hosp Trust, Bærum, Norway; Mohammad O Pervez, Jon Brynildsen, Akershus Univ Hosp, Lørenskog, Norway; Arnljot Tveit, Bærum Hosp, Vestre Viken Hosp Trust, Bærum, Norway; Kjetil Steine, Helge Røsjø, Torbjørn Omland, Akershus Univ Hosp, Lørenskog, Norway

11:30 AM

Board # 2184

High-sensitivity Troponin T Concentrations Improve Diagnostic and Prognostic Assessment in Patients With Acute Dyspnea

**Kristian Berge** , Magnus Nakrem Lyngbakken, Gunnar Einvik, Jacob Andreas Winther, Jon Brynildsen, Ragnhild Roysland, Heidi Strand, Akershus Univ Hosp, Lørenskog, Norway; Geir Christensen, Oslo Univ Hosp, Oslo, Norway; Arne Didrik Hoeiseth, Torbjoern Omland, Helge Røsjø, Akershus Univ Hosp, Lørenskog, Norway

11:30 AM

Board # 2186

Cardiac Autoimmunity is Associated With Subclinical Myocardial Dysfunction in Type 1 Diabetes

**Giovane R Sousa** , Joslin Diabetes Ctr, Harvard Medical Sch, Boston, MA; Mikhail N Kosiborod, Saint Luke's Mid America Heart Inst, Kansas City, MO; David A Bluemke, Univ of Wisconsin Sch of Med and Public Health, Madison, WI; Myra A. Lipes, Joslin Diabetes Ctr, Harvard Medical Sch, Boston, MA

11:30 AM

Board # 2187

Differences in the Plasma Proteome Between Heart Failure With Preserved and Reduced Ejection Fraction: Insights From the Penn Heart Failure Study

Julio A Chirinos, Univ of Pennsylvania, Philadelphia, PA; Lei Zhao, Bristol-Myers Squibb, Pennington, NJ; Yi Jia, Somalogic, Boulder, CO; **Ashwin Murthy** , Univ of Pennsylvania, Philadelphia, PA; Michael Basso, Bruce Car, Bristol-Myers Squibb, Pennington, NJ; David A Gordon, Bristol-Myers Squibb Company, Doylestown, PA; Thomas P Cappola, Univ Pennsylvania Sch of Med, Philadelphia, PA

11:30 AM

Board # 2188

Biologic Pathways Associated With Adverse Outcomes in Heart Failure With Preserved Ejection Fraction: Insights From Plasma Proteomics

Julio A Chirinos, **Ashwin Murthy** , Univ of Pennsylvania, Philadelphia, PA; Lei Zhao, Bristol-Myers Squibb, Pennington, NJ; Yi Jia, Bristol-Myers Squibb, Boulder, CO; Michael Basso, Bruce Car, Bristol-Myers Squibb, Pennington, NJ; David A Gordon, Bristol-Myers Squibb Company, Doylestown, PA; Thomas P Cappola, Univ Pennsylvania Sch of Med, Philadelphia, PA

11:30 AM

Board # 2189

Rho-Associated Kinase Activity Correlates With the Presence of Diastolic Dysfunction in Patients With Normal Left Ventricular Ejection Fraction

**Brian Yu** , Hatem Al Kassem, Li Ma, Tess Allan, Kathryn Dryer, Linus Park, Jui Malwankar, Gerardo Perla, John Blair, James K Liao, Univ of Chicago, Chicago, IL

11:30 AM

Board # 2190

High Collagen Type VI Formation is a Strong Independent Predictor of Poor Outcomes in Heart Failure With Preserved Ejection Fraction: The TOPCAT Trial

**Julio A Chirinos** , Univ of Pennsylvania, Philadelphia, PA; Lei Zhao, Bristol Myers Squibb, Pennington, NJ; Federica Genovese, Nordic Bioscience, Herlev; Mary Ellen Cvijic, Bristol Myers Squibb, Pennington, NJ; Michael Basso, Bristol-Myers Squibb, Pennington, NJ; Alexander Reese-Petersen, Nordic Bioscience, Herlev; Melissa Yarde, BMS, Princeton, NJ; Zhaoqing Wang, Bristol-Myers Squibb, Princeton, NJ; Dietmar Seiffert, Bristol-Myers Squibb, Lawrenceville, NJ; Morten Karsdal, Nordic Biosciences, Herlev, Denmark; Litao Zhang, Bruce Car, Bristol-Myers Squibb, Pennington, NJ; David A Gordon, Bristol Myers Squibb Company, Doylestown, PA; Thomas P Cappola, Univ Pennsylvania Sch of Med, Philadelphia, PA

11:30 AM

Board # 2191

A Targeted Plasma Multi-Marker Approach With Machine Learning for Risk Stratification in HFpEF: The TOPCAT Trial

Julio A Chirinos, **Alena Orlenko** , Univ of Pennsylvania, Philadelphia, PA; Lei Zhao, Bristol Myers Squibb, Pennington, NJ; Michael Basso, Mary E Cvijic, Bristol-Myers Squibb, Pennington, NJ; Zhuyin Li, BMS, Princeton, NJ; Thomas Spires, Bristol-Myers Squibb, Pennington, NJ; Melissa Yarde, BMS, Princeton, NJ; Zhaoqing Wang, Bristol-Myers Squibb, Princeton, NJ; Dietmar Seiffert, Bristol-Myers Squibb, Lawrenceville, NJ; Stuart Prenner, Univ of Pennsylvania, Philadephia, PA; Payman Zamani, Priyanka T Bhattacharya, Univ of Pennsylvania, Philadelphia, PA; Anupam Kumar, Vanderbilt Univ, Nashville, TN; Kenneth Margulies, Univ of Pennsylvania, Philadelphia, PA; Litao Zhang, Bruce Car, Bristol-Myers Squibb, Pennington, NJ; David A Gordon, Bristol Myers Squibb Company, Doylestown, PA; Jason Moore, Univ of Pennsylvania, Philadelphia, PA; Thomas P Cappola, Univ Pennsylvania Sch of Med, Philadelphia, PA

11:30 AM

Poster Professor

Brian Houston, Charleston, SC

# Abstract Poster Session

## HF.APS.38 - Novel Findings in Cardiomyopathy

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2232

**Development and Validation of a New Risk Prediction Score for Life-Threatening** **Ventricular Tachyarrhythmias in Laminopathies**

**Karim Wahbi** , Cochin Hosp, Paris, France; LMNA working group

11:30 AM

Board # 2233

Seasonal Variation in Incidence of Takotsubo Cardiomyopathy: Analysis From Nationwide Inpatient Sample

Keerat Rai Ahuja, Mohamed M Gad, Cleveland Clinic, Cleveland, OH; Antonette Karrthik, Cleveland Clinic Fndn, Cleveland, OH; **Najdat Bazarbashi** , Univ of Maryland, Baltimore, MD; Manpreet Kaur, Cleveland Clinic Fndn, Cleveland, OH; Kelly Fening, Cleveland Clinic Fndn, Strongsville, OH; David Majdalany, Cleveland Clinic Fndn, Cleveland, OH; Mouin S Abdallah, Cleveland Clinic, Cleveland, OH

11:30 AM

Board # 2234

A Patient With Barth Syndrome

**Arjun Kanwal** , MedStar Health Internal Med Residency Program, Baltimore, MD; Jason Kaplan, McLaren Oakland Internal Med Residency, Southfield, MI; Raman Bharaj, MedStar Health Internal Med Residency Program, Baltimore, MD; Aditya Saini, Medstar Union Memorial Hosp, Baltimore, MD

11:30 AM

Board # 2235

ST-revelations: Thinking Critically in the Critically Ill

**Zachary Il'Giovine** , Cleveland Clinic, Cleveland, OH; Jerry Lipinski, Cleveland Clinic, Shaker Heights, OH; Ruchi Sharma, Cleveland Clinic, Cleveland, OH; Divyang Patel, Cleveland Clinic, Cleveland; Venu Menon, Allan L Klein, Steven Nissen, Cleveland Clinic, Cleveland, OH

11:30 AM

Board # 2236

Continuous vs. Intermittent Arrhythmia Monitoring in Pediatric and Adult Patients With Left Ventricular Noncompaction (LVNC)

**John L Jefferies** , Univ of Tennessee, Memphis, TN; David Spar, Cincinnati Childrens Hosp Medical Ctr, Cincinnati, OH; A Sami Chaouki, Lurie Children's Hosp of Chicago, Chicago, IL; Paula Casson, Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; Jeffrey A Towbin, Le Bonheur Childrens Hosp, Memphis, TN; Richard J Czosek, Cincinnati Childrens Hosp, Cincinnati, OH

11:30 AM

Board # 2237

Cryoglobulinemic Vasculitis: An Atypical Presentation With Myocardial Involvement

**Shea A Ford** , Jonathan Pollock, UPMC, Pittsburgh, PA

11:30 AM

Board # 2238

White Ethnicity is Associated With Increased Mortality and Incidence of Ischemic Stroke in Chagas Disease

**Yazan Sawalha** , Sohab Radwan, Raja Zaghlol, Hector Garcia-Garcia, Medstar Washington Hosp Ctr, Washington, DC

11:30 AM

Board # 2239

Restrictive Cardiomyopathy With Constrictive Physiology as a Late Complication of Radiation Therapy

**Ayman Nasir** , Francisco Merced-Ortiz, Ochsner Clinic Fndn, New Orleans, LA

11:30 AM

Board # 2240

Increased Sympathetic Activity in Hypertrophic Cardiomyopathy Patients With Obstructive Sleep Apnea - Implications for Arrhythmia and Sudden Death

**Shreyas Venkataraman** , Aiswarya Rajendran, Naima Covassin, Jan Bukartyk, Jeffrey B Geske, Meghna Prabhdas Mansukhani, Mayo Clinic, Rochester, MN; Anwar A Chahal, Univ of Pennsylvania, Havertown, PA; Virend K Somers, Mayo Clinic, Rochester, MN

11:30 AM

Board # 2241

A Randomised Controlled Trial of Dapagliflozin on Left Ventricular Hypertrophy in Patients With Type Two Diabetes. The DAPA-LVH Trial

**Alex Brown** , Stephen Gandy, Rory McCrimmon, Allan Struthers, Univ of Dundee, Dundee, United Kingdom; Chim Choy Lang, Univ of Dundee, Dundee

# Abstract Poster Session

## IM.APS.12 - Nuclear Medicine Evaluation of Cardiac Disease

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 4186

Impact of a Novel Myocardial Perfusion Imaging Risk Classification Scheme on Referral for Coronary Angiography, Revascularization, and Mortality

**Anirudh Kumar** , Divyang R. Patel, Neil L. Greenberg, Paul C. Cremer, Serge C Harb, Ajay Bhargava, Samir R Kapadia, Venu Menon, Rory Hachamovitch, Wael A. Jaber, Cleveland Clinic Fndn, Cleveland, OH

11:30 AM

Board # 4187

**Simultaneous Evaluation of Myocardial Viability Between Late Gadolinium Enhancement Transmurality and** 18 **F-fluorodeoxyglucose Uptake in Patients With Chronic Total Occlusion Using by Hybrid Positron Emission Tomography/Magnetic Resonance Imaging**

**Takatoyo Kiko** , Fukushima Medical Univ, Fukushima City, Japan; Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

11:30 AM

Board # 4188

**Comparison of Diagnostic Performance of Relative Flow Reserve With Coronary Flow Reserve By** 13 **N-ammonia Positron Emission Tomography to Detect Coronary Artery Disease**

**Takatoyo Kiko** , Fukushima Medical Univ, Fukushima City, Japan; Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

11:30 AM

Board # 4189

**Direct Comparisons of Left Ventricular Volume and Function by Simultaneous Cardiac Magnetic Resonance Imaging and Gated** 13 **N-ammonia Positron Emission Tomography**

**Takatoyo Kiko** , Fukushima Medical Univ, Fukushima City, Japan; Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

11:30 AM

Board # 4190

**Diagnostic Utility of Cardiac Magnetic Resonance/** 18 **F-fluorodeoxyglcose Positron Emission Tomography Fusion Imaging in Cardiac Sarcoidosis**

**Masakazu Yasuda** , Kindai Univ. Hosp, Osakasayama, Osaka, Japan; Yoshinori Kagioka, Saiseikai Tondabayashi Hosp, Sakai-Shi,Osaka, Japan; Mana Okune, Kindai Universtiy Hosp, Osakasayama, Japan; Kakehi Kazuyoshi, Takayuki Kawamura, Kindai Univ. Hosp, Osakasayama, Osaka, Japan; Hayato Kaida, Kindai Univ. Hosp, Osakasayama, Japan; Kazunari Ishii, Kindai Univ. Hosp, Osakasayama, Osaka, Japan; Yoshitaka Iwanaga, Kindai Univ. Hosp, Osakasayama, Japan; Kindai University Hospital, Cardiology

11:30 AM

Board # 4191

**Relationship Between Coronary Arterial** 18 **F-sodium Fluoride Uptake and Epicardial Adipose Tissue Analyzed on Computed Tomography**

**Toshiro Kitagawa** , Yumiko Nakamoto, Hiroshima Univ Graduate Sch of Biomedical and Health Sciences, Hiroshima, Japan; Ko Sasaki, Yutaka Hirokawa, Hiroshima Heiwa Clinic, Hiroshima, Japan; Yasuki Kihara, Hiroshima Univ Graduate Sch of Biomedical and Health Sciences, Hiroshima, Japan

11:30 AM

Board # 4192

Prognostic Relationship Between Coronary Artery Calcium Score, Perfusion Defects and Myocardial Flow Reserve in Patients With Suspected Coronary Artery Disease

**Krishna Kaushik Patel** , Poghni A Peri-Okonny, Femina S Patel, Saint Luke's Mid America Heart Inst, Kansas City, MO; John Spertus, Mid America Heart Inst, Kansas City, MO; Brett Sperry, Cleveland Clinic, Cleveland, OH; Paul Chan, Saint Lukes Hosp / MAHI, Kansas City, MO; A Iain McGhie, Saint Luke's Mid America Heart Inst, Kansas City, MO; Randall Thompson, Saint Luke's Mid America Heart Inst, Kansas City, MO, Kansas City, MO; Firas Al Badarin, Saint Lukes Mid America Heart Ins, Kansas City, MO; Kevin F Kennedy, Saint Luke's Mid America Heart Inst, Kansas City, MO; Timothy M Bateman, St. Luke's Cardiovascular Consultants, Kansas City, MO

11:30 AM

Board # 4193

PET-MRI of LAA Thrombus in Patients With Atrial Fibrillation Using a Novel Fibrin-Binding Radiotracer

**David Izquierdo-Garcia** , Massachusetts General Hosp, Charlstown, MA; Anne Philip, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Rory B Weiner, Moussa Mansour, Massachusetts General Hosp, Boston, MA; Ciprian Catana, Ciprian Catana, Charlstown, MA; Peter Caravan, Massachusetts General Hosp, Charlestown, MA; David E Sosnovik, Massachusetts General Hosp, Harvard Medical Sch, Charlestown, MA

11:30 AM

Board # 4194

Metformin Improves Metabolic, Functional, and Structural Abnormalities in Spontaneously Hypertensive Rat Hearts

**Jie Li** , Krzysztof Minczuk, James Massey, Jack Roy, Soumen Paul, James Patrie, Robert Carey, Univ of Virginia, Charlottesville, VA; Heinrich Taegtmeyer, McGovern Medical Sch, Univ of Texas Health Science Ctr, Houston, TX; Susanna Keller, Bijoy Kundu, Univ of Virginia, Charlottesville, VA

11:30 AM

Board # 4195

**Clinical Implications of** 18 **F-sodium Fluoride Uptake in Subclinical Aortic Valve Calcification: Its Relation to Coronary Atherosclerosis and Predictive Value**

**Toshiro Kitagawa** , Yumiko Nakamoto, Hiroshima Univ Graduate Sch of Biomedical and Health Sciences, Hiroshima, Japan; Ko Sasaki, Yutaka Hirokawa, Hiroshima Heiwa Clinic, Hiroshima, Japan; Yasuki Kihara, Hiroshima Univ Graduate Sch of Biomedical and Health Sciences, Hiroshima, Japan

11:30 AM

Board # 4196

Percutaneous or Surgical Revascularization Are Associated With Survival Benefit in Stable Coronary Artery Disease

**Robert JH Miller** , Cedars Sinai Medical Ctr, Los Angeles, CA; Robert O Bonow, Northwestern Univ, Chicago, IL; Heidi Gransar, Cedars Sinai Medical Ctr, Los Angeles, CA; Rebekah Park, Cedars-Sinai Medical Ctr, Los Angeles, CA; Cecilia Hurtado, John Friedman, Sean Hayes, Louise Elizabeth Jane Thomson, Balaji Tamarappoo, Cedars Sinai Medical Ctr, Los Angeles, CA; Alan Rozanski, Cedars Sinai Medical Ctr, New York, NY; Torsten Doenst, Univ Jena, Jena, Germany; Daniel Berman, Cedars-Sinai Medical Ctr, Los Angeles, CA

11:30 AM

Board # 4197

Bone Marrow Adipose Tissue Volume: A Novel CT Imaging Marker of Cardiovascular Diseases Risk

**Shady Abohashem** , Tawseef Dar, Michael T. Osborne, Ahmed A Tawakol, Massachusetts General Hosp-Harvard Medical Sch, Boston, MA

11:30 AM

Board # 4198

**Diagnosing Implantable Cardiac Device Infection in Cases of Clinical Uncertainty Using** 18 **F-FDG-Positron Emission Tomography; Reducing Ambiguity With Nuclear Cardiology**

**Oliver G Wright** , Univ Of Manchester, Manchester, United Kingdom; Mohammad Ali, Central Manchester Fndn Trust, Manchester, United Kingdom; Matthew J Memmott, Central Manchester Univ Hosp NHS Fndn Trust, Manchester, United Kingdom; Fozia Ahmed, Manchester Univ NHS FNDTN Trust, Manchester, United Kingdom

11:30 AM

Board # 4199

Decreased Skeletal Muscle, but Not Increased Fat is Independently Associated With Coronary Microvascular Dysfunction and Adverse Cardiovascular Outcomes

**Ana Carolina do A. H. de Souza** , Brigham and Women's Hosp, Boston, MA; Michael Rosenthal, Dana-Farber Cancer Inst, Boston, MA; Sanjay Divakaran, Brigham and Women's Hosp, Boston, MA; Michael T Osborne, Massachusetts General Hosp, Boston, MA; Navkaranbir S Bajaj, Univ of Alabama at Birmingham, Birmingham, AL; Courtney F Bibbo, Jon Hainer, Ron Blankstein, Sharmila Dorbala, Marcelo F Di Carli, Viviany R Taqueti, Brigham and Women's Hosp, Boston, MA

11:30 AM

Board # 4200

Improving Performance of Technetium-99m Pyrophosphate Imaging for Transthyretin Cardiac Amyloidosis

**Daniel R Davies** , John Wells W Askew, Joanne Benson, Panithaya Chareonthaitawee, Geoffrey Johnson, Robert Glynn, Eli Muchtar, Angela Dispenzieri, Morie A Gertz, Martha Grogan, Margaret M Redfield, Omar F. AbouEzzeddine, Mayo Clinic, Rochester, MN

11:30 AM

Board # 4201

Influence of Rate Pressure Product Correction on Reclassification of Myocardial Flow Reserve

**Gaurav Sharma** , Rochester Regional Health, Rochester, NY; Albert Deluca, Sabahat Bokhari, Kathleen R Flaherty, Andrew J Einstein, Columbia Univ Medical Ctr, New York, NY

# Abstract Poster Session

## QU.APS.06 - Outcomes Variation and Disparities

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 3152

Differences in Patient Healthcare Experience by Geographic Region Among Adults With Atherosclerotic Cardiovascular Disease

**Eve-Marie Benson** , Johns Hopkins Univ, Baltimore, MD; Victor Okunrintemi, East Carolina Univ, Greenville, NC; Martin Tibuakuu, St. Luke's Hosp, Ballwin, MO; Oluseye Ogunmoroti, Johns Hopkins Univ, Baltimore, MD; Safi Ullah Khan, West Virginia Univ, Morgantown, WV; Adeyemi Taiwo, East Carolina Univ, Greenville, NC; Martha Gulati, Univ of Arizona, Phoenix, AZ; Roger S Blumenthal, Johns Hopkins Univ, Baltimore, MD; Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD

11:30 AM

Board # 3153

Trends in Cardiovascular Mortality and Economic Distress in Communities

**Sameed Ahmed M Khatana** , Ashwin Nathan, Elias J Dayoub, Univ of Pennsylvania, Philadelphia, PA; Dhruv S Kazi, Beth Israel Deaconess Medical Ctr, Boston, MA; Robert W Yeh, Beth Israel Deaconess Med Ctr, Boston, MA; Peter W Groeneveld, Univ of Pennsylvania, Philadelphia, PA; S V Subramanian, Harvard T.H. Chan Sch of Public Health, Philadelphia, PA

11:30 AM

Board # 3154

Age Differences in the Safety and Effectiveness of the Heart Pathway Accelerated Diagnostic Protocol for Acute Chest Pain

**Jason P Stopyra** , Anna C Snavely, Brian J Wells, Wake Forest Univ Sch of Med, Winston-Salem, NC; David M Herrington, Wake Forest Univ Sch Medici, Winston Salem, NC; Brian C Hiestand, Chadwick D Miller, Wake Forest Univ Sch of Med, Winston-Salem, NC; Simon A Mahler, Wake Forest Sch Med, Winston Salem, NC

11:30 AM

Board # 3155

The DISCO Study: Does Interventionalists' Sex Impact Coronary Outcomes?

**Prasanthi Yelavarthy** , Milan Seth, Univ of Michigan, Ann Arbor, MI; Elizabeth Pielsticker, Henry Ford Allegiance, Jackson, MI; Cindy L Grines, Northwell Health, Manhasset, NY; Claire S Duvernoy, VA Medical Ctr, Ann Arbor, MI; Hitinder S Gurm, Univ of Michigan, Ann Arbor, MI

11:30 AM

Board # 3156

Procedural Volume and Outcomes After Primary Angioplasty for ST-Segment Elevation Myocardial Infarction in Kerala, India: Results of the Cardiology Society of India-Kerala Primary Angioplasty Registry

Anoop Mathew, Univ of Alberta Hosp, Edmonton, AB, Canada; A Jabir, Lisie Hosp, Kochi, India; Yinggan Zheng, Cindy Westerhout, Univ of Alberta Hosp, Edmonton, AB, Canada; Sunitha Viswanathan, Government Medical Coll Hosp, Thiruvanathapuram, India; Placid Sebastian, Pariyaram Medical Coll Hosp, Kannur, India; Prasanna Kumar, Jubilee Mission Medical Coll Hosp, Thrissur, India; Kevin R Bainey, Univ of Alberta, Edmonton, AB, Canada; **Robert C Welsh** , Mazankowski Alberta Heart Inst, Edmonton, AB, Canada

11:30 AM

Board # 3157

Gender Differences in Coronary Artery Bypass Grafting in California

**Limin Wang** , Holly Hoegh, Christopher Krawczyk, Office of Statewide Health Planning and Development, Sacramento, CA

11:30 AM

Board # 3158

Dramatic Variation in Cardiac Rehabilitation Use After Coronary Artery Disease Events

**Michael P Thompson** , Hechuan Hou, John D Syrjamaki, Univ of Michigan, Ann Arbor, MI; Alphonse DeLucia III, Bronson Methodist Hosp, Kalamazoo, MI; Donald S Likosky, Univ Michigan, Ann Arbor, MI; Hitinder S Gurm, Univ of Michigan, Ann Arbor, MI; Devraj Sukul, Univ of Michigan Health Syste, Ann Arbor, MI

11:30 AM

Board # 3159

Lost to Follow-up Bias May Commonly Alter Primary Outcome in Cardiovascular Randomised Trials

**Lucas CW Fong** , Univ of Glasgow, Glasgow, United Kingdom; Tom Ford, Univ of Glasgow, Glasgow; Bruno da Costa, St. Michael's Hosptial - Applied He, Toronto, ON, Canada; Peter Juni, St. Michael's Hosp - Applied He, Toronto, ON, Canada; Colin Berry, Univ of Glasgow, Scotland

11:30 AM

Board # 3160

Age-specific Differences in Patient Reported Outcomes Among Adults With Atherosclerotic Cardiovascular Disease: Medical Expenditure Panel Survey 2006 - 2015

**Victor Okunrintemi** , East Carolina Univ, Greenville, NC; Eve-Marie Benson, Johns Hopkins Univ, Baltimore, MD; Ouassim Derbal, East Carolina Univ, Greenville, NC; Michael D Miedema, Minneapolis Heart Inst, Minneapolis, MN; Roger S Blumenthal, Johns Hopkins Hosp, Baltimore, MD; Martin Tibuakuu, St. Luke's Hosp, Ballwin, MO; Oluseye Ogunmoroti, Johns Hopkins Medical Insts, Baltimore, MD; Safi Ullah Khan, West Virginia Univ, Morgantown, WV; Mamas Andreas Mamas, Univ of Keele, keele; Martha Gulati, Univ of Arizona, Phoenix, AZ; Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD

11:30 AM

Board # 3161

Longitudinal Practice Patterns and Outcomes Among HIV-Infected Patients After Treatment for Acute Coronary Syndromes

**Monica Parks** , Univ of California San Francisco, San Francisco, CA; Eric A Secemsky, Robert W Yeh, Changyu Shen, Eunhee Choi, Dhruv S Kazi, Beth Israel Deaconess Medical Ctr, Boston, MA; Priscilla Hsue, Univ of California San Francisco, San Francisco, CA

11:30 AM

Poster Professor

Stacie L Daugherty, Aurora, CO

# Abstract Poster Session

## CH.APS.16 - Pediatric Heart Failure and Transplant

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 4119

Impact of Medical Management on Transplant-Free Survival in Pediatric Dilated Cardiomyopathy

**Jenna Ashkanase** , Aamir Jeewa, Katelyn Arathoon, Sunghoon Minn, Seema Mital, Anne I Dipchand, Emilie Jean-St-Michel, Hosp for Sick Children, Toronto, ON, Canada

11:30 AM

Board # 4120

Brain Natriuretic Peptide is an Independent Prognostic Factor in Patient With Late-Stage Duchenne Muscular Dystrophy

**Jung-Joon Cha** , Young Hak Jung, Severance Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Chul Shin, Ju Young Kim, Eui-Young Choi, Jong-Youn Kim, Pil-Ki Min, Young Won Yoon, Byoung-Kwon Lee, Bum-Kee Hong, Hyuck Moon Kwon, Won Ah Choi, Seong-Woong Kang, Se-Joong Rim, Gangnam Severance Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of

11:30 AM

Board # 4121

A Cost-effectiveness Analysis of Ventricular Assist Devices (VAD) for the Treatment of Systolic Heart Failure in Pediatric Patients

**Bryant Priromprintr** , Nancy Song, Douglas K Owens, Joshua Salomon, Seo-Ho Cho, Sony Ton, Diana Y Zhao, Christopher S Almond, Stanford, Palo Alto, CA; David N Rosenthal, Stanford Univ, Palo Alto, CA; Jeremy D Goldhaber-Fibert, Stanford, Palo Alto, CA; Andrew Shin, Stanford Children's Health, Menlo Park, CA

11:30 AM

Board # 4122

ACCURACY OF INITIAL EVEROLIMUS DOSING IN THE TEAMMATE TRIAL: HOW WELL DOES IT WORK IN PEDIATRIC HEART TRANSPLANTATION?

**Joanne Lee** , Lucile Packard Children's Hosp Stanford, Palo Alto, CA; Chesney D Castleberry, Washington Univ in St. Louis, Saint Louis, MO; Matthew Bock, Loma Linda Univ, Loma Linda, CA; Scott R Auerbach, Children's Hosp Colorado, Aurora, CO; Joseph W Rossano, Children's Hosp of Philadelphia, Haverford, PA; Seth A Hollander, Stanford Univ, Palo Alto, CA; Ashwin K Lal, U of Utah Primary Children's Hos, Salt Lake City, UT; Elfriede Pahl, Ann & Robert H. Lurie Childs Hosp, Chicago, IL; Lynsey Barkoff, Lucile Packard Children's Hosp Stanford, Palo Alto, CA; Gloria L Klein, Boston Children's Hosp, Boston, MA; Christopher S Almond, Stanford Univ, Palo Alto, CA; Lynn A Sleeper, Kevin P Daly, Boston Children's Hosp, Boston, MA

11:30 AM

Board # 4123

Intravenous Iron Replacement Therapy With Ferric Carboxymaltose is Safe and Effective in Pediatric Patients With Heart Failure

**Joseph A Spinner** , Kriti Puri, Jacquelyn Powers, Tejasvi Dasari, Hari Tunuguntla, Swati Choudhry, Antonio G Cabrera, Mona Shah, William J Dreyer, Susan W Denfield, Baylor Coll of Med, Houston, TX; Jack F. Price, Texas Children's Hosp, Houston, TX

11:30 AM

Board # 4124

The Fontan Immunophenotype and Post-Transplant Outcomes in Children: A Multi-Institutional Study

**Benjamin S Mantell** , NewYork-Presbyterian, New York, NY; Estela Azeka, Heart Inst (InCor), Sao Paulo, Brazil; Ryan S Cantor, Kirklin Inst for Res in Surgical Outcomes, Birmingham, AL; Waldemar F Carlo, UAB, Birmingham, AL; Maryanne Chrisant, Joe Dimaggio Childrens Hosp, Hollywood, FL; John C Dykes, Stanford Univ, Palo Alto, CA; Timothy M Hoffman, UNC Children's, Chapel Hill, NC; James K Kirklin, The Univ of Alabama at Birmingham, Birmingham, AL; Devin Koehl, Kirklin Inst for Res in Surgical Outcomes, Birmingham, AL; Thomas J L'Ecuyer, Univ of Virginia Health System, Charlottesville, VA; Jennie M McAllister, NewYork-Presbyterian, New York, NY; Adriana C Prada-Ruiz, Nemours/Alfred I. duPont Hosp for Children, Wilmington, DE; Marc E Richmond, NewYork-Presbyterian, New York, NY

11:30 AM

Board # 4125

Prevalence of Hypertension After Pediatric Heart Transplantation

**Neha Bansal** , Children's Hosp at Montefiore, New York, NY; Waheed Raedi, Children's Hosp at Montefiore, Bronx, NY; Shivanand S Medar, Montefiore Medical Ctr, Bronx, NY; Kimberly Beddows, Children's Hosp at Montefiore, Bronx, NY; Daphne T Hsu, Albert Einstein Med Colle, Bronx, NY; Jacqueline M Lamour, Childrens Hosp at Montefiore, Bronx, NY; Joseph Mahgerefteh, Children's Hosp at Montefiore, Bronx, NY

11:30 AM

Board # 4126

Beneficial Stroke-Free Survival of Paracorporeal Continuous Flow Support in Children: A Single-Center Experience

**Ryan S Bishop** , UT Southwestern Medical Ctr, Dallas, TX; Jodie L Lantz, Children's Health Dallas, Dallas, TX; Nathanya Baez-Hernandez, Maria Bano, Ryan J Butts, UT Southwestern Medical Ctr, Dallas, TX; Robert D Jaquiss, UT Southwestern Childrens Health, Dallas, TX; Ryan R Davies, David L Sutcliffe, UT Southwestern Medical Ctr, Dallas, TX

11:30 AM

Board # 4127

Prolonged Hospital Length of Stay After Pediatric Heart Transplantation and Its Impact on Outcomes: A PHTS Database Analysis

**Dipankar Gupta** , Univ of Florida, Gainesville, FL; Ryan Cantor, Devin Koehl, The Univ of Alabama at Birmingham, Birmingham, AL; Neha Bansal, Albert Einstein Coll of Med, New York, NY; Chesney D Castleberry, Washington Univ, St. Louis Sch of Med, Saint Louis, MO; Allison Kimbro, Univ of Florida, Gainesville, FL; Stephen Pophal, Univ of Arizona, Coll of Med, Phoenix, AZ; Kenneth O Schowengerdt Jr, Saint Louis Univ Sch of Med, Saint Louis, MO; Alfred Asante-Korang, Johns Hopkins All Childrens Hosp, Saint Petersburg, FL; Paolo Rusconi, Univ of Miami, Miami, FL; James K Kirklin, The Univ of Alabama at Birmingham, Birmingham, AL; David L Sutcliffe, UT Southwestern Medical Ctr, Dallas, TX

11:30 AM

Board # 4128

Pediatric Cardiac Retransplantation: A 25 Year Single Center Experience

**Nicole M DeMarais** , Chicago Medical Sch, Rosalind Franklin Univ, North Chicago, IL; Philip T Thrush, Michael C Monge, Ann & Robert H. Lurie Children's Hosp, Chicago, IL; Lauren Balmert, Northwestern Univ, Feinberg S, Chicago, IL; Carl L Backer, Ann & Robert H. Lurie Children's Hosp, Chicago, IL; Sarah J Wilkens, Stanford Univ, Palo Alto, CA; Bradley S Marino, Elfriede Pahl, Ann & Robert H. Lurie Children's Hosp, Chicago, IL

11:30 AM

Poster Professor

Kurt Schumacher, Ann Arbor, MI

# Abstract Poster Session

## HF.APS.34 - Pharmacological Approaches in HF and Cardiomyopathy: New Insights

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2192

A Minority of Patients With Cardiac Sarcoidosis Are Treated With Steroid-Sparing Immunosuppressants: Insights From the TriNetX Global Network Database

**Brian K Mitchell** , Huzaefah Jeelani Syed, Tamas Gal, Patrick Nana-Sinkam, F. Gerard Moeller, Kenneth A Ellenbogen, Antonio Abbate, Jordana Kron, Virginia Commonwealth Univ Medical Ctr, Richmond, VA

11:30 AM

Board # 2193

Clinical Outcomes Associated With Titration of Medical Therapy for Heart Failure With Reduced Ejection Fraction: From the HF-ACTION Trial

**Stephen J Greene** , Duke Univ Sch of Med, Durham, NC; Christopher M O'Connor, Inova Heart and Vascular Inst, Falls Church, VA; Jie-Lena Sun, Duke Univ Sch of Med, Durham, NC; Mona Fiuzat, Duke Univ, Arlington, VA; William E Kraus, Brooke Alhanti, Duke Univ Sch of Med, Durham, NC; Ileana L Pina, Detroit Medical Ctr Heart Hosp, Detroit, MI; David Whellan, Thomas Jefferson Univ, Philadelphia, PA; Robert John Mentz, Duke Clinical Res Inst, Hillsborough, NC

11:30 AM

Board # 2195

Beta Blockers for Heart Failure According to Natriuretic Peptide Levels

**Chan Soon Park** , Korea Advanced Inst of Science, Daejeon, Korea, Republic of; Jin Joo Park, Seoul Natl Univ Bundang, Seongnam-si; Il-Young Oh, Seoul Natl Univ Bundang Hosp, Seongnam, Korea, Republic of; Hyun-Ah Park, Dept of Family Med, Seoul, Korea, Republic of; Hyun-Jai Cho, Hae-young Lee, Seoul Natl Univ, Seoul, Korea, Republic of; Kye Hun Kim, Chonnam Natl Univ, Gwangju, Korea, Republic of; Byungsu Yoo, Cardiology Wonju Coll of Med, Wonju; Seok-Min Kang, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Sang Hong Baek, Seoul St. Mary's Hosp, Seoul, Kosovo, Republic of; Eun-Seok Jeon, Sungkyunkwan Univ Coll of Med, Seoul, Korea, Republic of; Jae-Joong Kim, Asan Medical Ctr, Seoul, Korea, Republic of; Myeong-Chan Cho, Chungbuk Natl Univ Hosp, Cheongju, Korea, Republic of; Shung Chull Chae, Kyungpook Natl Univ Coll of Med, Daegu, Korea, Republic of; Byung Hee H Oh, Seoul Natl Univ, Incheon, Korea, Republic of; Dong Choi, Seoul Natl Univ Bundang Hosp, Seongnan-si

11:30 AM

Board # 2196

Use of Sodium-Glucose Cotransporter 2 Inhibitors for Diuretic Resistance in Acute Decompensated Heart Failure Are Associated With Improved Diuretic Response

**Matthew Griffin** , Yale Sch of Med, New Haven, CT; Ralph J Riello III, Yale-New Haven Hosp, New Haven, CT; Oksana Kucher, Univ of Illinois at Chicago, Arlington Heights, IL; Juan Ivey-Miranda, Hosp de Cardiologia. Insto Mexicano del Seguro Social. Mexico City., Mexico City, Mexico; Veena S Rao, Devin Mahoney, Yale Sch of Med, New haven, CT; Megan Leila Baker, Yale Sch of Med, New Haven, CT; Jack McCormick, Yale Sch of Med, New Haven; Jeffrey M Testani, Yale, Guilford, CT

11:30 AM

Board # 2197

Clinical Role of Sacubitril/valsartan Therapy in Heart Failure With Reduced Ejection Fraction Patients With End Stage of Renal Disease; Beyond PARADIGM-HF Trial

**Seonhwa Lee** , Jaewon Oh, Jaehyung Ha, Kyeong-Hyeon Chun, Severance Cardiovascular Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of; Hyoeun Kim, Dept of Health Promotion, Severance Hosp, Seoul, Korea, Republic of; Chan Joo Lee, Sungha Park, Sang-Hak Lee, Seok-Min Kang, Severance Cardiovascular Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of

11:30 AM

Board # 2198

Contemporary Patterns of Utilization of Ivabradine and Sacubitril/Valsartan Among Medicare Beneficiaries

**Andrew Sumarsono** , Univ of Texas Southwestern Medical Ctr, Dallas, TX; Ezimamaka Ajufo, Univ of Texas Southwestern Medical Ctr, Dallas, TX; Muthiah Vaduganathan, Brigham and Women's Hosp, Cambridge, MA; Sandeep R Das, Ambarish Pandey, Univ of Texas Southwestern Medical Ctr, Dallas, TX

11:30 AM

Board # 2199

Raas Modulation Through ARNI Therapy but Not ACE-Inhibitor Therapy Improves Cardiac Systolic Function and Cardiac Aerobic Functional Capacity in Patients With HFrEF

**Avinash Kumar Pandey** , Michael G. DeGroote Sch of Med, Hamilton, ON, Canada; Jennifer Reinhart, A. Shekhar Pandey, Cambridge Cardiac Care Ctr, Cambridge, ON, Canada; Subodh Verma, St Michaels Hosp, Toronto, ON, Canada

11:30 AM

Board # 2200

Treprositinil in Pediatric Patients Listed for Heart Transplantation

**Seth A Hollander** , Stanford Univ Medical Ctr, Palo Alto, CA; Michelle T Ogawa, Esther Liu, Lucile Packard Children's Hosp, Stanford, Palo Alto, CA; Rachel K Hopper, Sharon Chen, David N Rosenthal, Stanford Univ, Palo Alto, CA; Jeffrey A Feinstein, Stanford Univ Medical Ctr, Palo Alto, CA

11:30 AM

Board # 2201

ATTRibute-CM: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Global Phase 3 Study of AG10 in Patients With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Julian David Gillmore, UCL, London; Pablo Garcia-Pavia, Hosp Puerta de Hierro, Majadahonda; Martha Grogan, Mayo Clinic, Rochester, MN; Mazen A Hanna, Cleveland Clinic, Cleveland, OH; Stephen B Heitner, Oregon Health and Science U, Portland, OR; Daniel Jacoby, Yale Sch of Med, New Haven, CT; Mathew S Maurer, New York Presbyterian Hosp, New York, NY; Claudio Rapezzi, Istituto di Cardiologia, Bologna, Italy; Sanjiv J Shah, Northwestern Univ, Chicago, IL; Jitendra Ganju, Leonid Katz, Jonathan Fox, Eidos Therapeutics, San Francisco, CA; **Daniel Judge** , Medical Univ of South Carolina, Charleston, SC

# Abstract Poster Session

## LF.APS.10 - Physical Activity and Fitness

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 3109

Athletes Performing Extraordinary Physical Activity (>10,000 MET∙Min/Week) at No Greater Risk of All-Cause or Cardiovascular Disease Mortality

**Laura F DeFina** , Beth B Wright, Benjamin L Willis, David Leonard, Steve Farrell, Andjelka Pavlovic, Ambrose J. Burfoot, The Cooper Inst, Dallas, TX; William L. Haskell, Stanford Univ, Palo Alto, CA; Nina B. Radford, Cooper Clinic, Dallas, TX; Benjamin D. Levine, UT Southwestern Medical Ctr, Dallas, TX

11:30 AM

Board # 3110

Meeting 24-Hour Movement Guidelines Among US Children and Adolescents: Prevalence and Age Trends, 2016-2017

**Ciarán P Friel** , Andrea T Duran, Ari Shechter, Keith M Diaz, Columbia Univ Medical Ctr, New York, NY

11:30 AM

Board # 3111

Physical Fitness and Long Term Blood Pressure Variability in Young Male Military Personnel

**Gen-Min Lin** , Hualien Armed Forces Gen Hosp, Hualien, Taiwan

11:30 AM

Board # 3112

Associations Between Steps and Years of Potential Life Lost in the US Population

**Charles A German** , Wake Forest Baptist Medical Ctr, Winston Salem, NC; Amanda C McClain, San Diego State Univ, San Diego, CA; Tali Elfassy, Univ of Miami, Miami, FL

11:30 AM

Board # 3113

Lifestyle Behaviors and Association With All-Cause Mortality and Cardiovascular Disease Events Among US Adults With Varying Levels of Kidney Function

**Sarah Schrauben** , Jesse Hsu, Univ of Pennsylvania, Philadelphia, PA; Sandra Amaral, Children's Hosp of Philadelphia, Philadelphia, PA; Amanda H Anderson, Tulane Univ, New Orleans, LA; Harold Ira Feldman, UPenn Perelman Sch of Med, Philadelphia, PA; Laura Dember, Univ of Pennsylvania, Philadelphia, PA

11:30 AM

Board # 3114

Impact of Chronic Obstructive Lung Disease on Cardio-respiratory Fitness and Respiratory Efficiency in Patients With Heart Failure

Jacinthe Boulet, Montreal Heart Inst, Montreal, QC, Canada; Jonathan N Myers, VA Palo Alto Health Care System, Palo Alto, CA; Jeffrey W Christle, Stanford Health Care, Fremont, CA; Ross Arena, Univ of Illinois, Chicago, IL; Leonard A Kaminsky, Ball State Univ, Muncie, IN; Anna Nozza, Montreal Heart Inst MHICC, Montreal, QC, Canada; Joshua Abella, US Dept of Veteran Affairs, Palo Alto, CA; **Michel White** , Montreal Heart Inst, Montreal, QC, Canada

11:30 AM

Board # 3115

Role of Cardiorespiratory Fitness to Modulate Cardiotoxicity in Long Term Cancer Survivors Exposed to Anthracycline Therapy

**Olga H Toro-Salazar** , Connecticut Childrens Medical Ctr, Hartford, CT; Ji Hyun Lee, Maua M Mosha, Tiffany Ruiz, Andrea Orsey, Connecticut Children's Medical Ctr, Hartford, CT; Carolyn Wilhelm, Rainbow Babies and Children's Hosp, Cleveland, OH; Kristine S Partovi Hauser, Massachusetts General Hosp, Boston, MA; Shailendra Upadhyay, Connecticut Childrens Medical Ctr, Hartford, CT; Kan N Hor, Nationwide Children's Hosp, Columbus, OH

11:30 AM

Board # 3116

Simple Questionnaire About Sedentary Time Identifies Excess Body Weight, Hypertension and Diabetes

Hisako Tsuji, Hlth Examiation Ctr of Moriguchi, Moriguchi, Osaka, Japan; **Sueyoshi Hiroyuki** , Yuzo Akita, Osaka Saiseikai Izuo Hosp, Osaka, Japan; Ichiro Shiojima, Kansai Medical Univ, Hirakata, Japan

11:30 AM

Board # 3117

Passive Smartphone Actigraphy Data Predicts Heart Failure Decompensation

**Ayse S Cakmak** , Georgia Inst of Technology, Atlanta, GA; Hugh J. Lanier, Emory Univ, Atlanta, GA; Erik Reinertsen, Georgia Inst of Technology, Atlanta, GA; Arash Harzand, Emory Univ Sch of Med, Atlanta, GA; Abarmard Maziar Zafari, Emory Univ, Decatur, GA; Mhd Alaa Hammoud, Mercer Univ, Atlanta, GA; Alaaeddin Alrohaibani, Atlanta VA Medical Ctr, Decatur, GA; Candy Wakwe, Michael Appeadu, Gari D Clifford, Amit J Shah, Emory Univ, Atlanta, GA

# Abstract Poster Session

## EP.APS.23 - Predicting & Preventing Heart Failure In the General Population

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 3000

Trajectories of Time-Varying Changes in Adiposity, Metabolic Syndrome and Coronary Artery Calcium Significantly Predict Risks of Heart Failure and Its Subtypes in The Multi-Ethnic Study of Atherosclerosis

**Longjian Liu** , Drexel Univ, Philadelphia, PA; Joao A Lima, Wendy S Post, Moyses Szklo, Johns Hopkins Univ, Baltimore, MD

11:30 AM

Board # 3001

Global Electrical Heterogeneity as a Predictor of Incident Heart Failure in Males and Females

**Hassan Khan** , Emory Univ, Atlanta, GA; Jukka A Lipponen, Univ of Eastern Finland, Kuopio, Finland; Mikhael F El-Chami, New York Univ Sch of Med, Atlanta, GA; Sudhir Kurl, Res Inst Public Health, Kuopio, Finland; Javed Butler, Emory, Atlanta, GA; Jari A Laukkanen, Univ of Eastern Finland, Kuopio, Finland

11:30 AM

Board # 3002

Racial Differences in Malignant Left Ventricular Hypertrophy and Incidence of Heart Failure: A Multi-Cohort Study

**Alana Lewis** , Colby Ayers, UT Southwestern Medical Ctr, Dallas, TX; Elizabeth Selvin, Johns Hopkins Univ, Baltimore, MD; Ian J Neeland, UT Southwestern Medical Ctr, Dallas, TX; Christie M Ballantyne, Baylor Coll Med, Houston, TX; Vijay Nambi, Veterans Affairs Hosp, Sugar Land, TX; Ambarish Pandey, UTSW Medical Ctr, Dallas, TX; Tiffany M Powell-Wiley, Natl Insts of Health, Silver Spring, MD; Mark H Drazner, UT Southwestern, Dallas, TX; Mercedes R Carnethon, Northwestern Univ, Chicago, IL; Jarett D Berry, UT Southwestern Medical Sch, Dallas, TX; Stephen L Seliger, Univ of Maryland Sch of Med, Baltimore, MD; Christopher DeFilippi, Inova, Falls Church, VA; James A De Lemos, UT Southwestern Medical Ctr, Dallas, TX

11:30 AM

Board # 3003

Temporal Changes in Resting Heart Rate in Young Adults, Long-term Cardiac Structure and Function, and Incident Heart Failure and Cardiovascular Disease in Middle Age

**Chike C Nwabuo** , Johns Hopkins Univ, Baltimore, MD; Duke Appiah, Texas Tech Univ HSC, Lubbock, TX; Henrique T Moreira, Henrique D Vasconcellos, Johns Hopkins Univ, Baltimore, MD; Queen Nnenna Aghaji, Johns Hopkins Univ, Chicago, IL; Bharath Ambale Venkatesh, Johns Hopkins Univ, Baltimore, MD; Jamal S Rana, Kaiser Permanente, Oakland, CA; Norrina B Allen, Donald M Lloyd-Jones, Northwestern Univ, Chicago, IL; Pamela Schreiner, Univ Minnesota, Minneapolis, MN; Samuel Gidding, FH Fndn, Pasadena, CA; Joao A Lima, Johns Hopkins Univ, Baltimore, MD

11:30 AM

Board # 3004

Joint Influence of Diabetes and Heart Failure on All-Cause Mortality Among US Adults

**Haohan Wei** , New York Univ, New York, NY; Andrew Nicholson, VA New York Harbor Healthcare System, New York, NY; Binhuan Wang, Sundar Natarajan, New York Univ Sch of Med, New York, NY

11:30 AM

Board # 3005

Dysphagia Severity is an Independent Predictors of Short-term Outcomes in Patients With Acute Exacerbation of Heart Failure

**Junichi Yokota** , Natl Hosp Organization Sendai Medical Ctr, Sendai, Japan; Yoshiko Ogawa, Teikyo Univ, Tokyo, Japan; Masahiro Kohzuki, Tohoku Univ Graduated Sch of Med, Sendai, Japan

11:30 AM

Board # 3006

Incremental Prognostic Value of Polypharmacy on the Comorbidities in Patients With Acute Decompensated Heart Failure; Insights From OPAR (Osaka Prefectual Acute Heart Failure Registry)

**Kiyomi Kayama** , Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masahiro Seo, Osaka General Medical Ctr, Osaka City, Japan; Makoto Abe, Jun Nakamura, Kyoko Yamamoto, Osaka General Medical Ctr, Osaka, Japan; Masatsugu Kawahira, Osaka General Medical Ctr, Oosaka, Japan; Kazuya Tanabe, Masatake Fukunami, Osaka General Medical Ctr, Osaka, Japan

11:30 AM

Board # 3007

Change in Ankle Brachial Index and Subsequent Risk of Heart Failure and Atrial Fibrillation in Patients With Chronic Kidney Disease

**Kirsten S. Dorans** , Tulane Univ Sch of Public Health and Tropical Med, New Orleans, LA; Jing Chen, Tulane Sch of Med, New Orleans, LA; Amanda H Anderson, Katherine T Mills, Tulane Univ, New Orleans, LA; Nisha Bansal, Univ of Washington, Seattle, WA; Alan S Go, Kaiser Permanente Northern Cal, Oakland, CA; Bernard G. Jaar, Johns Hopkins Univ Sch of Med, Baltimore, MD; Mayank M. Kansal, Univ of Illinois at Chicago, Chicago, IL; Rupal C. Mehta, Feinberg Sch of Med, Chicago, IL; Mahboob Rahman, Case Western Reserve Univ, Solon, OH; Panduranga Rao, Univ of Michigan Health System, Ann Arbor, MI; Hernan Rincon-Choles, Cleveland Clinic Fndn, Cleveland, OH; Sylvia E. Rosas, Joslin Diabetes Ctr, Boston, MA; Matthew R. Weir, Univ of Maryland Sch of Med, Baltimore, MD; Jiang He, Tulane Univ, New Orleans, LA

11:30 AM

Board # 3008

Visceral Fat and BNP Levels Are Linked to the Pathophysiological Mechanisms of HFpEF in High Risk Middle-Aged Individuals

**Christopher M Hearon Jr.** , Michinari Hieda, Katrin A Dias, Mitchel Samels, Braden Everding, Margot Morris, Dean Palmer, Sheryl A Livingston, James Patrick Macnamara, Benjamin D Levine, Satyam Sarma, Inst for Exercise and Environmental Med, Texas Health Presbyterian Dallas and Univ of Texas Southwestern Medical Ctr, Dallas, TX

11:30 AM

Board # 3009

Temporal Changes in Left Ventricular Ejection Fraction and Their Prognostic Impacts in Patients With Stage B Heart Failure: Insights From the Chart-2 Study

**Hajime Aoyanagi** , Tohoku Univ Grad Sch Med, Sendai-shi Miyagi, Japan; Kotaro Nochioka, Yasuhiko Sakata, Masanobu Miura, Takashi Shiroto, Tohoku Univ Grad Sch Med, Sendai-shi Miyagi, Japan; Ruri Abe, Tohoku Univ Grad Sch Med, Sendai shi-Mi yagi, Japan; Shintaro Kasahara, Tohoku Univ Grad Sch Med, Sendai-shi Miyagi, Japan; Masayuki Sato, Tohoku Univ Grad Sch Med, Sendai-shi Miyagi, Japan; Takahide Fujihashi, Tohoku Univ Grad Sch Med, Sendai-shi Miyagi, Japan; Shinsuke Yamanaka, Tohoku Univ Grad Sch Med, Sendai-shi Miyagi, Japan; Hideka Hayashi, Tohoku Univ Grad Sch Med, Sendai-shi Miyagi, Japan; Koichiro Sugimura, Jun Takahashi, Satoshi Miyata, Tohoku Univ Grad Sch Med, Sendai-shi Miyagi, Japan; Hiroaki Shimokawa, Tohoku Univ Grad Sch Med, Sendai City, Japan

11:30 AM

Poster Professor

Faraz S Ahmad, Chicago, IL

11:30 AM

Board # 3010

EHR-Based Modeling Specifically Identifies Patients With Primary Aldosteronism

Xiruo Ding, Imran Ajmal, Univ of Pennsylvania, Philadelphia, PA; Scott O Trerotola, Hosp Univ Pennsylvania, Philadelphia, PA; Douglas Fraker, Jordana Cohen, Heather Wachtel, **Daniel S Herman** , Univ of Pennsylvania, Philadelphia, PA

11:30 AM

Board # 3011

Differences in Primary Prevention Recommendations for Statin Therapy Based on National Guidelines Using the Pooled Cohort Equation Risk versus the Coronary Artery Calcium Score: Preliminary Findings From the Vanguard Study for the CorCal Randomized Clinical Outcomes Trial

**Joseph Brent Muhlestein** , Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT; Kirk Ute Knowlton, Intermountain Medical Ctr, Salt Lake City, UT; Viet T Le, Intermountain Medical Ctr, Rocky Mountain Univ of Health Professions, Salt Lake City, UT; Donald L Lappe, Heidi T May, David Byung Min, Kevin Johnson, Shanelle Cripps, Lesley Schwab, Shelbi Braun, Intermountain Medical Ctr, Salt Lake City, UT; Tami L Bair, Intermountain Medical Ctr, Salt Lake Cty, UT; Jeffrey Lance Anderson, Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT

# Abstract Poster Session

## HF.APS.32 - Prognosis in Heart Failure/Cardiomyopathy

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Poster Professor

Akshay S Desai, Boston, MA

11:30 AM

Board # 2172

Liver Stiffness Assessed by Noninvasive Marker Fibrosis 4 Index is Associated With Right Ventricular Functionand Cardiovascular Prognosis in Patients With Heart Failure With Preseved Ejection Fraction

**Mitsutaka Nakashima** , Satoru Sakuragi, Iwakuni Clinical Ctr, Iwakuni, Japan

11:30 AM

Board # 2173

Diflunisal is Associated With Improved Mortality in Patients With Wild-Type ATTR Cardiac Amyloidosis: The BU Amyloidosis Center Experience

**Yuliya Y Mints** , John L Berk, Boston Medical Ctr, Boston, MA; Lawreen Connors, Boston Univ Sch of Med, Boston, MA; Gheorghe Doros, Boston Univ Sch of Public Health, Boston, MA; Deepa M Gopal, Boston Medical Ctr, Boston, MA; Shivangi Kataria, Boston Univ Sch of Public Health, Boston, MA; Graham Lohrmann, Alexandra R Pipilas, Boston Medical Ctr, Boston, MA; Frederick L Ruberg, Boston Universiy Sch of Med, Boston, MA; Omar K Siddiqi, Boston Medical Ctr, Boston, MA

11:30 AM

Board # 2174

Increase in the Hospital Readmission Rate Among Heart Failure Patients in a Population-Based Study

**Michail Giakoumis** , Davit Sargsyan, John B Kostis, Rutgers Robert Wood Johnson Medical Sch, New Brunswick, NJ; Javier Cabrera, Rutgers Univ, Piscataway, NJ; Georgia Barbayannis, William J. Kostis, Rutgers Robert Wood Johnson Medical Sch, New Brunswick, NJ; For the Myocardial Infarction Data Acquisition System Study Group

11:30 AM

Board # 2175

Spironolactone Use at Discharge is Associated With Improved Outcomes in Hospitalized Patients With Heart Failure With Borderline Ejection Fraction

**Nobuyuki Enzan** , Kyushu Univ, Fukuoka, Japan; Shouji Matsushima, Kyushu Univ Hosp, Fukuoka, Japan; Tomomi Ide, Hidetaka Kaku, Taiki Higo, Hiroyuki Tsutsui, Kyushu Univ, Fukuoka, Japan

11:30 AM

Board # 2176

Effects of Sacubitril-Valsartan Compared With Enalapril on Pulmonary Artery Pressure in Patients With Heart Failure and Reduced Ejection Fraction

**Akshay S Desai** , Amil M Shah, Brigham Womens Hosp, Boston, MA; Gary F Mitchell, Cardiovascular Engineering, Norwood, MA; Brian L Claggett, Brigham and Women's Hosp, Boston, MA; James C Fang, Univ of Utah Health Science Ctr, Salt Lake City, UT; Cheryl A Abbas, Ricardo A Rocha, Novartis Pharmaceuticals Corp, East Hanover, NJ; Scott D Solomon, Brigham and Women's Hosp, Boston, MA

11:30 AM

Board # 2177

Copd and Heart Failure, A Bad Combo: Comparison of Outcomes in Patients With Heart Failure in Acute Exacerbation With versus Without Chronic Obstructive Pulmonary Disease

**Hassaan B Arshad** , Julius M Gardin, Rutgers New Jersey Medical Sch, Newark, NJ

11:30 AM

Board # 2178

Frequency and Clinical Impact of Hyperkalemia Within a Large General Population of Heart Failure Patients

**Joseph Brent Muhlestein** , Intermountain Medical Ctr, Univ of Utah, Salt Lake City, UT; Jennifer Kammerer, Relypsa, Inc, Redwood City, CA; Tami L Bair, Intermountain Medical Ctr, Salt Lake Cty, UT; Kirk Ute Knowlton, Intermountain Medical Ctr, Salt Lake City, UT; Viet T LE, Intermountain Medical Ctr, Rocky Mountain Univ of Health Professions, Salt Lake City, UT; Jeffrey Lance Anderson, Donald L Lappé, Heidi T May, Intermountain Medical Ctr, Salt Lake City, UT

11:30 AM

Board # 2179

Renal Function on Admission is Associated With Future Left Ventricular Ejection Fraction Recovery in Patients With Acute Heart Failure: Insights From an Exploratory Analysis of General Clinical Parameters

**Yuki Irie** , Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Hiroyuki Takahama, Natl Cardiovascular Ctr, Suita, Japan; Yasuhiro Hamatani, Natl Cerebral and Cardiovascular Ct, Osaka, Japan; Masashi Amano, Natl Cerebral and Cardiovascula, Suita, Japan; Atsushi Okada, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Makoto Amaki, Natl Cerebral and Cardiovascula, Suita, Japan; Takuya Hasegawa, Natl Cerebal & Cardiovascular Ctr, Suita Osaka, Japan; Hideaki Kanzaki, Natl Cardiovascular Ctr, Osaka, Japan; Satoshi Yasuda, Natl Cereb Cardiovascular Ctr, Osaka, Japan; Chisato Izumi, Natl Cerebral and Cardiovacular, Suita, Japan

11:30 AM

Board # 2180

Reduced Change in Heart Rate Between the Upright and Supine Positions Indicates Cardiac Overload in Japanese Patients With Cardiovascular Risk Factor: The Cardiovascular Prognostic Coupling Study

**Yusuke Oba** , Jichi Medical Univ Hosp, Tochigi, Japan; Tomoyuki Kabutoya, Jichi Medical Univ, Shimotsuke Tochigi, Japan; Satoshi Hoshide, Jichi Medical Univ, Shimotsuke, Japan; Kazuomi Kario, Jichi Medical Univ, Tochigi-ken, Japan

11:30 AM

Board # 2181

Plasma and Cardiac Mir-155 and Mir-425 Levels Are Downregulated in Acute Heart Failure: Biomarker and Pathophysiologic Implications

**Yang Chen** , Xiao Ma, Seethalakshmi R Iyer, John C Burnett, Mayo Clinic, Rochester, MN

# Abstract Poster Session

## AT.APS.17 - Regulation of Vascular Inflammation

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 1010

Mir-499 Released From Cardiomyocytes Contributes to the Surged Vascular Injury After Acute Myocardial Infarction

**Xitong Dang** , Southwest Medical Univ, Luzhou, China

11:30 AM

Board # 1011

Residual Inflammation Indicated by High Sensitive C-reactive Protein Predict Worse Long-term Clinical Outcomes in Asian Patients Undergoing Percutaneous Coronary Interventions

**Norihito Takahashi** , Juntendo Univ, Bunkyo-ku, Tokyo, Japan; Tomotaka Dohi, Takehiro Funamizu, Juntendo Univ, Tokyo, Japan; Hirohisa Endo, Juntendo Univ, Bunkyo-ku, Tokyo, Japan; Hideki Wada, Juntendo Univ Shizuoka Hospit, Izunokuni Shizuoka, Japan; Shinichiro Doi, Juntendo Univ, Tokyo, Japan; Manabu Ogita, Juntendo Univ, Izunokuni, Japan; Hiroshi Iwata, Juntendo Univ, Tokyo, MA, Japan; Shinya Okazaki, Kikuo Isoda, Katsumi Miyauchi, Kazunori Shimada, Juntendo Univ, Tokyo, Japan

11:30 AM

Board # 1012

IL-1 Beta Signaling Characterization in Human Immune Cells by Mass Cytometry

**Hema Kothari** , Chantel McSkimming, Corey Williams, Mythili Vigneshwar, Eli Zunder, Coleen McNamara, Univ of Virginia, Charlottesville, VA

11:30 AM

Board # 1013

PFKFB3-mediated Metabolic Reprogramming to Glycolysis Promotes Inflammation in Human Arterial Endothelial Cells

**Wusheng Xiao** , William Oldham, Joseph Loscalzo, Brigham and Women's Hosp, and Harvard Medical Sch, Boston, MA

11:30 AM

Poster Professor

Mark W Feinberg, Boston, MA

11:30 AM

Board # 1014

Soluble Lectin-like Oxidized Low-density Lipoprotein Receptor-1 is Associated With Hdl Dysfunction and High-risk Coronary Plaque in Psoriasis

**Amit K. Dey** , NHLBI,Natl Insts of Health, Bethesda, MD; Ranjitha Gaddipati, AstraZeneca, Ashburn, VA; Milena Aksentijevich, Harry Choi, Youssef Elnabawi, NHLBI,Natl Insts of Health, Bethesda, MD; Emily Ongstad, AstraZeneca, Potomac, MD; Colin Scott, Noor O. Khalil, Justin Rodante, Paula Anzenberg, Mina Al Najafi, Aarthi Reddy, NHLBI,Natl Insts of Health, Bethesda, MD; Heather Teague, NHLBI,Natl Insts of Health, Rockville, MD; Jenis Argueta-Amaya, Alexander Sorokin, NHLBI,Natl Insts of Health, Bethesda, MD; Aditya A Joshi, NHLBI, Bethesda, MD; Martin Playford, NHLBI, Natl Insts of Health, Bethesda, MD; Marcus Chen, NHLBI,Natl Insts of Health, Bethesda, MD; Sotirios Karathanasis, AstraZeneca, Gaithersburg, MD; Joel Gelfand, Univ of Pennsylvannia, Philadelphia, PA; Ruchi Gupta, AstraZeneca, Gaithersburg, MD; Nehal N Mehta, NIH, Bethesda, MD

11:30 AM

Board # 1015

Anti-Thrombin Nanoparticles Minimize Kidney Ischemia-Reperfusion Injury by Reducing Inflammation and Preserving Vascular Integrity

**Ian A Vargas** , Univ of South Florida MCOM, Tampa, FL; Daniel Stephenson, Charles Chalfant, Univ of South Florida, Tampa, FL; Hua Pan, Samuel Wickline, Tampa, FL

11:30 AM

Board # 1016

Contrasting Effects of Eicosapentaenoic and Arachidonic Acid on Membrane Cholesterol Crystal Formation Under Hyperglycemic Conditions

Samuel C.R. Sherratt, Elucida Res LLC, Beverly, MA; **R Preston Mason** , Brigham and Women's Hosp, Boston, MA

11:30 AM

Board # 1017

Ldl-Induced Changes in Monocyte Populations and Ccr2 Expression Profile as a Potential Contributor to Cvd Risk in African Americans

**Cristhian A Gutierrez-Huerta** , Quan Yu, Valerie Mitchell, Billy Collins, Natl Insts of Health, Bethesda, MD; Amit K. Dey, NHLBI,Natl Insts of Health, Bethesda, MD; Martin Playford, Natl Insts of Health, Bethesda, MD; Nehal N Mehta, NIH, Bethesda, MD; Yvonne Baumer, Natl Insts of Health, Bethesda, MD; Tiffany M Powell-Wiley, Natl Insts of Health, Silver Spring, MD

11:30 AM

Board # 1018

Circulating Immune Profile of Aging, a Translational Study on the Role of Growth Differentiation Factor-15 and Monokine Induced by Interferon gamma

**Jennifer A Arthur** , Stanford Cardiovascular Inst, Palo Alto, CA; Sara Bouajila, Stanford Cardiovascular Inst, Stanford, CA; Myriam Amsallem, Stanford Univ, Palo Alto, CA; Shai Shen Orr, Technion's Medical Sch Campus, Israel, Israel; Yukari Kobayashi, Stanford Cardiovascular Inst, Palo Alto, CA; Yael Rosenberg-Hasson, Stanford Univ, Palo Alto, CA; Ayelet Alpert, Technion's Medical Sch Campus, Israel, Israel; Kegan James Moneghetti, Stanford Univ, Stanford, CA; Cornelia Dekker, Kevin Contrepois, Beth A Martin, Stanford Univ, Palo Alto, CA; Tatiana Kouznetsova, Ku Leuven, Leuven, Belgium; Mark Davis, Stanford Inst for Immunity, Transplantation and Infection, Palo Alto, CA; Ioannis Karakikes, Stanford Univ, Palo Alto, CA; Holden T Maecker, Stanford Univ, Stanford, CA; Francois Haddad, Stanford Univ, Palo Alto, CA

# Abstract Poster Session

## HF.APS.37 - Risk Stratification in Heart Failure

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2222

**The Associated Ventilatory Abnormalities and Prognostic Values of H** 2 **Fpef Score in Patients With Heart Failure and Preserved Ejection Fraction**

**Shih-Hsien Sung** , Taipei Veterans General Hosp, Taipei, Taiwan

11:30 AM

Board # 2223

Impact of Anemia on Prognosis of Acute Heart Failure Patients With Mid-Range Left Ventricular Ejection Fraction

**Shinji Jinno** , Fujita Health Univ Hosp, Toyoake, Japan; Akira Yamada, Fujita Health Univ Sch of Med, Toyoake, Japan; Kazuhiro Nakamura, Kunihiko Sugimoto, Fumihiko Kitagawa, Takashi Ishikawa, Fujita Health Univ Hosp, Toyoake, Japan; Junichi Ishii, Fujita Health Univ, Toyoake, Japan; Yukio Ozaki, Fujita Health Univ Sch of Med, Toyoake, Japan

11:30 AM

Board # 2224

Prognostic Value of Cardiac Iodine-123 Metaiodobenzylguanidine Imaging is Influenced by Presence or Absence of Diabetes Mellitus in Patients Admitted for Acute Decompensated Heart Failure

**Shunsuke Tamaki** , Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Masahiro Seo, Makoto Abe, Jun Nakamura, Kyoko Yamamoto, Kiyomi Kayama, Masatsugu Kawahira, Kazuya Tanabe, Kunpei Ueda, Takanari Kimura, Daisuke Sakamoto, Yuto Tamura, Takeshi Fujita, Masatake Fukunami, Osaka General Medical Ctr, Osaka, Japan

11:30 AM

Board # 2225

Prognostic Impact of Malnutrition and Sarcopenia in Men versus Women With Acute Decompensated Heart Failure

**Takahisa Yamada** , Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Masato Kawasaki, Atsushi Kikuchi, Tsutomu Kawai, Osaka General Medical Ctr, Osaka, Japan; Masahiro Seo, Osaka General Medical Ctr, Osaka City, Japan; Jun Nakamura, Makoto Abe, Kyoko Yamamoto, Kiyomi Kayama, Osaka General Medical Ctr, Osaka, Japan; Masatsugu Kawahira, Osaka General Medical Ctr, Oosaka, Japan; Kazuya Tanabe, Yuto Tamura, Takeshi Fujita, Masatake Fukunami, Osaka General Medical Ctr, Osaka, Japan

11:30 AM

Board # 2226

Precipitant Factors of Heart Failure Decompensation in Patients Attended in Primary Care, the Hefestos Study

**Miguel-Angel Munoz** , Inst Català de la Salut. IDIAP, Barcelona, Spain; Helene Vaillant-Roussel, Univ Clermont Auvergne, Clermont-Ferrand, France; Liam Glynn, Univ of Limerick, Limerick, Ireland; Radost Assenova, Medical Univ of Plovdiv, Plovdiv, Bulgaria; Peter Torzsa, Semmelweis Univ, Budapest, Hungary; Lea Gril, Maribor Medical Sch, Maribor, Slovenia; Heidrun Lingner, Univ of Hannover, Hannover, Germany; Jacopo Demurtas, Univ of Tuscany, Firenze, Italy; Hans Thulesius, Lund Univ, Lund, Sweden; Djurdjica Lazic, Medical Sch Univ of Zagreb, Zagreb, Croatia; Jose-Maria Verdu-Rotellar, Inst Català de la Salut. IDIAP, Barcelona, Spain; Rosa Abellana, Facultat de Medicina. Univ de Barcelona, Barcelona, Spain

11:30 AM

Board # 2227

Use of the Biomarker NT-proBNP to Triage Patients Into Multidisciplinary Heart Function Clinic

**Calvin Ka Wing Tong** , Tatyana Danylyshyn, Univ of British Columbia, Vancouver, BC, Canada; Susan Kerr, Shari Hurst, Vancouver Island Health Authority, Victoria, BC, Canada; Elizabeth Swiggum, Univ of British Columbia, Vancouver, BC, Canada

11:30 AM

Board # 2228

Tobacco Smoking Predicts Worse Outcomes in Hospitalized Patients With Takotsubo Cardiomyopathy

**Raja Zaghlol** , Laith Ali, Medstar Georgetown Univ Hosp/ Washington Hosp Ctr, Washington, DC; Ana Barac, MedStar Heart and Vascular Inst, Washington, DC

11:30 AM

Board # 2229

Recurrent Heart Failure Hospitalizations Increase Risk of Cardiovascular and All-Cause Mortality in All Patients With Heart Failure and in Those With Preserved or Reduced Ejection Fraction: An Analysis From Pygargus Database in Sweden

Krister Lindmark, Umeå Univ, Umea, Sweden; Kurt Boman, Skellefteå County Hosp, Skelefteå, Sweden; Jan Stalhammar, Uppsala university, Uppsala, Sweden; Mona Olofsson, Skellefteå County Hosp, Skellefteå, Sweden; Raquel Lahoz, Rachel Studer, Novartis Pharma AG, Basel, Switzerland; Aaron Levine, Eleni Kopsida, Anna Castelo-Branco, IQVIA Solutions, Solna, Sweden; Clare Proudfoot, **Stefano Corda** , Novartis Pharma AG, Basel, Switzerland; Anna Lundberg, Novartis Sverige AB, Kista, Sweden; Ana Filipa Fonseca, Novartis Pharma AG, Basel, Switzerland; Charlotte Pettersson, IQVIA Solutions, Solna, Sweden; Gerhard Wikstrom, Akademisha, Uppskla, Sweden

11:30 AM

Board # 2230

Remote Pulmonary Artery Hemodynamic Monitoring System Progressively Reduces Hospital Re-Admissions in Heart Failure Patients: 2-Year Real World Data Outcomes

**Smitha Narayana Gowda** , Univ of South Dakota Sanford Sch of Med, Sioux Falls, SD; Udit Bhaskar Bhatnagar, Univ of South Dakota, Sioux Falls, SD; Adam Stys, Univ of South Dakota Sanford Sch of Med, Sioux Falls, SD; Tom Stys, Sanford Health, Sioux Falls, SD; Marian S Petrasko, Univ of South Dakota Sanford Sch of Med, Sioux Falls, SD; Naveen Rajpurohit, Sanford USD Medical Ctr, Sioux Falls, SD; Valerie Bares, Univ of South Dakota, Sioux Falls, SD; Orvar Jonsson, Sanford Cardiovascular Inst, Sioux Falls, SD

11:30 AM

Board # 2231

Non-Heart Failure Admitting Diagnosis and Outcomes in Older Patients With Heart Failure With Preserved and Reduced Ejection Fraction (HFpEF and HFrEF)

**Gauravpal Singh Gill** , MedStar Washington Hosp Ctr, Washington, DC; Awais Malik, Georgetown Univ Hosp, Washington DC, DC; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; Ali Ahmed, VA Medical Ctr, Washington, DC

# Abstract Poster Session

## SA.APS.13 - Science in Mechanisms and Management of Aortic Valve Disease and Aortopathy

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Poster Professor

Dan J Fintel, Chicago, IL

11:30 AM

Board # 4272

Favorable Outcomes After Contemporary Aortic Arch Surgery With Single Carotid Cannulation Strategy for Selective Antegrade Cerebral Pefusion With Moderate Hypothermic Circulatory Arrest: A Seven- Year Single Center Experience

**Virna L. Sales** , Nargis Gafur, Julia Wendel, Armin Gorski, Khaled Alhussini, Khaled Hamouda, Kiril Penov, Attila Magyar, Dejan Radaković, Rainer G. Leyh, Constanze Bening, Univ Hosp of the Julius-Maximilians-Univ of Würzburg, Wuerzburg, Germany

11:30 AM

Board # 4273

Synchrotron-based 4D-X-ray Phase Tomography of Fresh Aortic Wall of Acute Aortic Dissection

**Takuro Tsukube** , Japanese Red Cross Kobe Hosp, Kobe, Japan; Koki Yokawa, Kobe Univ Graduate Sch of Med, Kobe, Japan; Chikashi Nakai, Japanese Red Cross Kobe Hosp, Kobe, Japan; Masato Hoshino, Naoto Yagi, JASRI/SPring8, Sayo, Japan; Kazunori Nakagawa, Kyushu Univ, Fukuoka, Japan; Yutaka Nakashima, Japanese Red Cross Fukuoka Hosp, Fukuoka, Japan

11:30 AM

Board # 4274

Saphenous Vein Grafts Anastomosed on a Dacron Conduit Show Comparable One-Year Patency to Saphenous Grafts Anastomosed on the Native Aorta

Miriam Bass, **Emilie Leroux** , Laval Hosp, Quebec, QC, Canada; Pierre Voisine, Eric Dumont, IUCPQ, Quebec, QC, Canada; Francois Dagenais, Laval Hosp, Quebec, QC, Canada

11:30 AM

Board # 4275

Biochemical Characteristics of the Aortic True Lumen Wall, False Lumen Wall and Flap During the Acute Phases of Type A Aortic Dissection in Humans

**Amer Harky** , Liverpool Heart and Chest Hosp, Liverpool, United Kingdom; Ya Hua Chim, Hannah A Davies, Univ of Liverpool, Liverpool, United Kingdom; Mark Field, Liverpool Heart and Chest Hosp, Liverpool, United Kingdom; Omar Nawaytou, Liverpool Heart and Chest Hosp, Liverpool; Riaz Akhtar, Jillian Madine, Univ of Liverpool, Liverpool, United Kingdom

11:30 AM

Board # 4276

Fluoroquinolones and the Risk of Aortopathy: A Systematic Review and Meta-Analysis

**Azka Latif** , Muhammad Junaid Ahsan, Creighton Univ, Omaha, NE; Saad Ullah Malik, Rawalpindi Medical Coll, Tucson, AZ; Noman Lateef, Vikas Kapoor, Muhammad Fazeel Anwar, Creighton Univ, Omaha, NE; Mohsin Mansoor Mirza, Mark J Holmberg, Creighton Univ Medical Ctr, Omaha, NE

11:30 AM

Board # 4277

Intracellular Interleukin 37 in Aortic Valve Cells Suppresses the Inflammatory Response to Soluble Extracellular Matrix Proteins Through Targeting Nucleus

**Erlinda The** , Lihua Ao, Yufeng Zhai, Suzhao Li, David A. Fullerton, Charles A. Dinarello, Xianzhong Meng, Univ of Colorado-Denver, Aurora, CO

11:30 AM

Board # 4278

Long Term Outcomes After Stentless Aortic Valve Replacement in Bicuspid Aortic Valve and Trileaflet Aortic Valve Patients: A Propensity Score Match Study

Linda Farhat, Univ of Michigan, Ann Arbor, MI; Aroosa Malik, Univ of Michigan Medical Sch, Ann Arbor, MI; Alexander Makkinejad, Emma St. Pierre, Univ of Michigan, Ann Arbor, MI; Mohamed-Ali Sareini, Wayne State Univ Sch of Med, Detroit, MI; Elizabeth L Norton, Creighton Univ Sch of Med, Omaha, NE; Xiaoting Wu, Francis D Pagani, Univ of Michigan, Ann Arbor, MI; Jonathan Haft, Univ Michigan, Ann Arbor, MI; Matthew A Romano, Richard L Prager, Karen Kim, Himanshu J Patel, G. Michael Deeb, **Bo Yang** , Univ of Michigan, Ann Arbor, MI

11:30 AM

Board # 4279

Charlson Comorbidity Index Predicts Longer-term Mortality and Re-admission in Isolated CABG

**Garrett N Coyan** , Hannah Chin, Ayesha Shah, Yisi Wang, Arman Kilic, Ibrahim Sultan, Christopher M Sciortino, Thomas G Gleason, Danny Chu, Univ of Pittsburgh, Pittsburgh, PA

11:30 AM

Board # 4280

Initial Surgery versus Conservative Management of Chronic Severe Aortic Regurgitation in Mild Symptomatic Older Patients

**Seung-Ah Lee** , Sahmin Lee, Ho Jin Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Jong-Min Song, Cheol-Hyun Chung, Duk-Hyun Kang, Jae-kwan Song, Jae-Won Lee, Dae-Hee Kim, Asan Medical Ctr, Seoul, Korea, Republic of

# Abstract Poster Session

## LF.APS.09 - Smoking, Alcohol Use and other Behavioral Risk Factors for CVD

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 3099

Alcohol Consumption and Ideal Cardiovascular Health in the General Population: From the Third National Health and Nutrition Examination Survey

**Muhammadimtiaz Ahmad** , Parag Anilkumar Chevli, Wake Forest Sch of Med, Winston Salem, NC; Mohamed F Almahmoud, Univ of Texas Medical Branch, Galveston, TX; Morgana Mongraw-Chaffin, Kristina H Lewis, Elsayed Z Soliman, Wake Forest Sch of Med, Winston Salem, NC

11:30 AM

Board # 3100

The Absolute Risk of Death and Cardiovascular Diseases in Past Smokers With a 10-year Cessation is Identical to the Risk in Never Smokers

**Masaki Ohsawa** , Kozo Tanno, Kuniaki Ogasawara, Iwate Medical Univ, Morioka, Japan; Kazuyoshi Itai, Morioka Univ, Takizawa, Japan; Yuki Yonekura, St. Luke's Intl Univ, Tokyo, Japan; Toru Kuribayashi, Iwate Univ, Morioka Iwate, Japan; Yoshihiro Morino, Tomonori Itoh, Iwate Medical Univ, Morioka, Japan; Fumiaki Takahashi, Iwate Medical Univ, Iwate Prefecture, Japan; Koichi Asahi, Yasushi Ishigaki, Shinichi Omama, Yasuhiro Ishibashi, Fumitaka Tanaka, Toshiyuki Onoda, Iwate Medical Univ, Morioka, Japan; Kiyomi Sakata, Iwate Medical Univ, Iwate Prefecture, Japan; Makoto Koshiyama, Iwate Health Service Association, Morioka, Japan; Megumi Tsubota, Iwate Medical Univ, Iwate Prefecture, Japan; Akira Okayama, Res Inst of Strategy for Prevention, Tokyo, Japan

11:30 AM

Board # 3101

Large Gaps in Coverage of Effective Policies to Prevent Youth Smoking Initiation: A Systematic Analysis of 195 Countries and Territories

**Marissa B Reitsma** , Vin Gupta, Thomas Hsiao, Hayley Tymeson, Nicholas Arian, Austin Tapp, Emmanuela Gakidou, Inst for Health Metrics and Evaluation, Seattle, WA

11:30 AM

Board # 3102

Resting Heart Rate Variability Parameters are Similar in Chronic Electronic Cigarette Users and Chronic Tobacco Cigarette Smokers

**Sara Arastoo** , Kacey P Haptonstall, Roya Moheimani, Yasmine Choroomi, Elizabeth Tran, Kevin Nguyen, Karishma Lakhani, Isabelle Ruedisueli, Jeffrey Gornbein, Holly R Middlekauff, UCLA Medical Ctr, Los Angeles, CA

11:30 AM

Board # 3103

Prevalence and Sociodemographic Variation in Non-Cigarette Tobacco Products Use Among Never Cigarette Smokers Adults in the United States

**Javier Valero Elizondo** , Yale Univ, New Haven, CT; S M Uddin, Johns Hopkins Sch of Med, Baltimore, MD; Aruni Bhatnagar, Andrew Paul DeFilippis, Univ of Louisville, Louisville, KY; Wasim Maziak, Florida Intl Univ, Miami, FL; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; Khurram Nasir, Baptist Health South Florida, New Haven, CT

11:30 AM

Board # 3104

Cigarette Smoking and Incident Coronary Heart Disease in African Americans: The Jackson Heart Study

**Adebamike A Oshunbade** , Karen A Valle, Wondwosen K Yimer, Arsalan Hamid, Donald Clark III, Univ of Mississippi Medical Ctr, Jackson, MS; Daisuke Kamimura, Yokohama City Univ Hosp, Yokohama, Japan; Wendy B White, Jackson Heart Study, Madison, MS; Andrew P DeFilippis, Univ of Louisville, Louisville, KY; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; Emelia J Benjamin, Boston Univ Sch of Med, Brookline, MA; Emily O'Brien, Duke Univ Medical Ctr, Durham, NC; Robert J Mentz, Duke Univ Medical Ctr, Hillsborough, NC; Carlos J Rodriguez, Wake forest Univ Sch of Med, Winstom Salem, NC; Ervin R Fox, Javed Butler, Univ of Mississippi Medical Ctr, Jackson, MS; Aruni Bhatnagar, Univ of Louisville, Louisville, KY; Rose Marie Robertson, American Heart Association, Dallas, TX; Adolfo Correa, Michael E Hall, Univ of Mississippi Medical Ctr, Jackson, MS

11:30 AM

Board # 3105

Using Electronic Cigarettes With Nicotine, but Not Without Nicotine, Increases Sympathetic Activity and Hemodynamic Variables in Chronic Electronic Cigarette Users

**Sara Arastoo** , Kacey P Haptonstall, Roya Moheimani, Yasmine Choroomi, Elizabeth Tran, Kevin Nguyen, Karishma S Lakhani, Isabelle Ruedisueli, Jeffrey Gornbein, Holly R Middlekauff, UCLA Medical Ctr, Los Angeles, CA

11:30 AM

Board # 3106

Electronic Cigarette Use is Associated With Altered Lipid Profiles in the CITU Study

**Sana Majid** , Boston Univ Sch of Med, Boston, MA; Kathleen Lucile McGlasson, Boston Univ Sch of Public Health, Boston, MA; Jessica L Fetterman, Boston Univ, Boston, MA; Rachel J Keith, Univ of Louisville, Louisville, KY; Robert M Weisbrod, Boston Univ Sch of Med, Boston, MA; Joseph Nicholas Palmisano, Boston Univ, Framingham, MA; Rosa Breton-Romero, Boston Univ Sch of Med, Cambridge, MA; Bihua Feng, Boston Univ Medical Ctr, Stoneham, MA; Comreen Vargees, Boston Univ Sch of Med, Boston, MA; Aruni Bhatnagar, Univ of Louisville, Louisville, KY; Rose Marie Robertson, American Heart Association, Dallas, TX; Naomi M Hamburg, Boston Univ Sch of Med, Boston, MA

11:30 AM

Board # 3107

Cardiac Toxicity of Flavorings in Electronic Nicotine Delivery Systems

**Obada Abou-Assali** , Michelle Reiser, Charles Szekeres, Sami Noujaim, Univ of South Florida, Tampa, FL

11:30 AM

Board # 3108

Effect Of Alcohol Consumption On The Risk Of Adverse Events In Atrial Fibrillation

**Chewan Lim** , Yonsei Univ Health System, Seoul, Korea, Republic of; Tae-Hoon Kim, Yonsei Univ Health System, Seoul; Myung-Jin Cha, Seoul Natl Univ Hosp, Seoul, Korea, Republic of; Jung Myung Lee, Kyung Hee Univ Hosp, Seoul, Korea, Republic of; Junbeom Park, Ewha Womans Univ, Seoul; Jin-Kyu Park, Yonsei Univ Health System, Seoul; Ki-woon Kang, Eulji Univ Hosp, Daejeon, Korea, Republic of; Jaemin Shim, Korea Univ Medical Ctr, Seoul; Jun Kim, Asan Medical Ctr, Seoul; Hyung Wook Park, Chonnam Natl Univ Hosp, Gwangju, Korea, Republic of; Eue-keun Choi, Seoul Natl Univ Hosp, Seoul, Korea, Republic of; Jin-Bae Kim, Kyung Hee Univ, Seoul, Korea, Republic of; Young Soo Lee, Daegu Catholic Univ Medical Ctr, Daegu, Korea, Republic of; Boyoung Joung, Yonsei Univ, Seoul, Korea, Republic of

# Abstract Poster Session

## QU.APS.05 - Social Determinants of Health

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 3141

Cardiovascular Disease Risk Factor Knowledge Among Monolingual Hispanics

**Maria Odette Gore** , Denver Health Medical Ctr, Denver, CO; Stephanie Coronel-Mockler, Colorado Prevention Ctr, Aurora, CO; Raymond Estacio, Mori J Krantz, Denver Health Medical Ctr, Denver, CO

11:30 AM

Board # 3142

A Sex and Race-Stratified Analysis of Mean Age of Hospitalizations and Subsequent All-Cause Mortality in Acute Myocardial Infarction

**Samarthkumar Jayeshkumar Thakkar** , Rochester General Hosp, Rochester, NY; Rupak Desai, Atlanta VA Medical Ctr, Decatur, GA; Manan Vyas, St. Martinus Faculty of Med, Willemstad, Curaçao; Ankit Vyas, Inova Heart and Vascular Inst, Falls Church, VA; Kartik Dhaduk, Westchester Medical Ctr, Valhalla, NY; Rushik Bhuva, Geisinger Wyoming Valley Medical Ctr, Wilkes-Barre, PA

11:30 AM

Board # 3143

Neighborhood-Level Poverty and Incident Heart Failure: Analysis of Electronic Health Records From 2005 to 2018

**Megan McCabe** , Kiarri Kershaw, Lindsay Pool, Northwestern Univ, Chicago, IL; Sadiya S. Khan, Northwestern Univ, Oak Park, IL

11:30 AM

Board # 3144

Neighborhood Socioeconomic Status and Performance Measure Adherence for Coronary Artery Disease and Atrial Fibrillation

**Mayank Sardana** , Univ of California SF, San Francisco, CA; Fatima Rodriguez, Stanford Univ, Stanford, CA; Yuanyuan Tang, Mid America Heart Inst, Kansas City, MO; Nihar R. Desai, Yale Sch of Med, New Haven, CT; Philip Jones, St. Luke's Mid America Heart Inst., Kansas City, MO; Salim S Virani, Michael E Debakey VA-Baylor, Bellaire, TX

11:30 AM

Board # 3145

The Structural and Social Determinants of Differences in Non-Adherence to Antihypertensive Medications Between Blacks and Whites

**Macarius M. Donneyong** , Teng-Jen Chang, Shawnita Sealy-Jefferson, The Ohio State Univ, Columbus, OH; John Jackson, Johns Hopkins Univ, Baltimore, MD; JaNelle Ricks, The Ohio State Univ, Columbus, OH; Paul D uarez, Meharry Medical Coll, Nashville, TN; Pamela Salsberry, The Ohio State Univ, Columbus, OH; Robert Otto Valdez, Univ of New Mexico, Alburquerque, NM; Bo Lu, The Ohio State Univ, Columbus, OH; Wansoo Im, Meharry Medical Coll, Nashville, TN; Michael Langston, Univ of Tennessee, Knoxville, TN; Darryl B. Hood, The Ohio State Univ, Columbus, OH; Michael Fischer, Brigham and Women's Hosp, Boston, MA

11:30 AM

Board # 3146

Association of the Robert Wood Johnson Foundation's Social Determinants of Health and Medicare Hospitalizations for Ischemic Stroke

**Andrew Wang** , Abel N Kho, Dustin D French, Northwestern Univ, Chicago, IL

11:30 AM

Board # 3147

Effects of Perceived Stress on Subjective and Objective Symptoms of Insomnia and Mental Health Among Patients With Heart Failure

**Allison E. Gaffey** , Yale Sch of Med, New Haven, CT; Sangchoon Jeon, Yale Sch of Nursing, Orange, CT; Matthew M. Burg, Yale Sch of Med, West Haven, CT; Daniel Jacoby, Yale Sch of Med, New Haven, CT; Samantha Conley, Nancy S Redeker, Yale Sch of Nursing, Orange, CT

11:30 AM

Board # 3148

Social Support, Communication, And Uncertainty Are Associated With Caregiver'S Perceptions Of Changes In Life Among Left Ventricular Assist Device Population

**Jingzhi Xu** , Johns Hopkins Univ Sch of Nursing, Baltimore, MD; Cheryl R Dennison Himmelfarb, Johns Hopkins Univ, Baltimore, MD

11:30 AM

Board # 3149

Financial Hardship Due to Medical Bills Amongst Families of Children With Congenital Heart Disease

**Avital B Ludomirsky** , Emily Bucholz, Boston Children's Hosp, Boston, MA; Jane W Newburger, Childrens Hosp Boston, Boston, MA

11:30 AM

Board # 3150

Outcomes and Care Quality Metrics for Women of Reproductive Age Living With Rheumatic Heart Disease in Uganda

**Andrew Young Chang** , Stanford Univ, Stanford, CA; Juliet Nabbaale, Emmy Okello, Uganda Heart Inst, Kampala, Uganda; Isaac Ssinabulya, Makerere Univ, Kampala, Uganda; Michele Barry, Stanford Univ, Stanford, CA; Andrea Beaton, Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; Allison R Webel, Bolton Sch of Nursing, Cleveland, OH; Christopher Longenecker, Case Western Reserve Univ, Cleveland, OH

11:30 AM

Poster Professor

Khurram Nasir, New Haven, CT

11:30 AM

Board # 3151

Clinical Usefulness of New R-R Interval Analysis Using Heart Rate Sensor WHS-1 to Identify Sleep Apnea Syndrome (SAS)

Takuo Arikawa, **Toshiaki Nakajima** , Akiko Haruyama, Hiroyuki Kaneda, Shigeru Toyoda, Dokkyo Medical Univ, Tochigi, Japan; Masao Nishimura, Nishimura Heart Clinic, Ageoshi, Japan; Tsutsumi Takeshi, Eda Memorial Hosp, Kanagawaken, Japan; Taishi Matsui, Akio Nakata, Union Tool Co. Ltd, Tokyo, Japan; Teruo Inoue, Dokkyo Medical Univ, Tochigi, Japan

# Abstract Poster Session

## AC.APS.06 - STEMI: From First Response to Post-Infarct Prognostication

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 4000

Trends in the Prehospital Care of ST-Elevation Myocardial Infarction in the United States: Lessons From STEMI EMS Activations in the NEMSIS Database

**Aditya C Shekhar** , Emma J Shimony, Mount Sinai Health System, New York City, NY; Jagat Narula, Icahn Sch of Med, New York, NY

11:30 AM

Board # 4001

Impact of Morphine Treatment on Infarct Size and Reperfusion Injury in Acute Reperfused ST-Elevation Myocardial Infarction

**Ingo Eitel** , Thomas Stiermaier, Univ Heart Ctr Lubeck, Lubeck, Germany; Georg T Fuernau, Univ of Leipzig Heart Ctr, Leipzig; Harald Langer, Univ Heart Ctr Lübeck, Lübeck, Germany; Steffen Desch, Univ of Leipzig Heart Ctr, Leipzig; Suzanne de Waha, Heart Ctr Leipzig, Leipzig; Juan Wang, Univ Heart Ctr Lübeck, Lübeck, Germany; Holger Thiele, Heart Ctrt Leipzig, Leipzig

11:30 AM

Board # 4002

Prognostic Implications of Admission Mitochondrial Biomarker Levels in Patients With St-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Intervention

**Nicola Cosentino** , Jeness Campodonico, Valentina Milazzo, Marco Moltrasio, Claudia Lucci, Ctr Cardiologico Monzino, Milan, Italy; Alice Bonomi, Ctr Cardiologico Monzino, Milano, Italy; Valeria Sbarra, Emilio Assanelli, Ctr Cardiologico Monzino, Milan, Italy; Monica de Metrio, Ctr Cardiologico Monzino, milano, Italy; Rubino Mara, Ctr Cardiologico Monzino, Milan, Italy; Giancarlo Marenzi, Ctr Cardiologico Monzino, IRCCS, Milan, Italy

11:30 AM

Board # 4003

Defining Cardiogenic Shock and Pre-shock in the Cardiac Intensive Care Unit

**Jacob C Jentzer** , Mayo Clinic, Rochester, MN; Sean Van Diepen, UNIVERSITY OF ALBERTA, Edmonton, AB, Canada; Barry Burstein, Gregory W Barsness, Mayo Clinic, Rochester, MN; Timothy Henry, The Christ Hosp, Cincinnati, OH; Venu Menon, Cleveland Clinic, Cleveland, OH; Srihari S Naidu, Westchester Medical Ctr, Hawthorne, NY; David A Baran, Sentara Heart Hosp, Virginia Beach, VA

11:30 AM

Board # 4004

Clinical Impact of Glycemic Variability on Left Ventricular Dysfunction Ata Chronic Phase in Patients Witha First St-segment Elevation Myocardial Infarction

**Jin Kirigaya** , Jin Kirigaya, Noriaki Iwahashi, Yokohama City Univ Medical Ctr, Yokohama, Japan; Masaomi Gohbara, Nanbu Hosp, Yokohama, Japan; Eiichi Akiyama, Kozo Okada, Yasushi Matsuzawa, Nobuhiko Maejima, Kiyoshi Hibi, Masami Kosuge, Toshiaki Ebina, Kouichi Tamura, Kazuo Kimura, Yokohama City Univ Medical Ctr, Yokohama, Japan

11:30 AM

Board # 4005

Cardiac Magnetic Resonance Myocardial Feature Tracking for Optimized Risk Assessment After Acute Myocardial Infarction in Patients With Type 2 Diabetes

Johannes Kowallick, Univ Medical Ctr Göttingen, Goettingen; Thomas Stiermaier, Univ Heart Ctr Luebeck, Luebeck, Germany; Torben Lange, Jenny-Lou Navarra, Alexander Koschalka, Univ Medical Ctr Göttingen, Goettingen, Germany; Karl-Philipp Rommel, Herzzentrum Leipzig, Leipzig, Germany; Joachim Lotz, Univ Medical Ctr Göttingen, Goettingen, Germany; Matthias Gutberlet, Heart Ctr Leipzig, Univ of Leipzig, Inst of Diagnostic and Interventional Radiology, Leipzig, Germany, Leipzig, Germany; Shelby Kutty, Johns Hopkins Med, Baltimore, MD; Gerd Hasenfuss, Univ Med Göttingen, Goettingen, Germany; Holger Thiele, Univ Leipzig - Heart Ctr, Leipzig; Ingo Eitel, Univ Med Luebeck, Leipzig, Germany; **Andreas Schuster** , Univ Medical Ctr Göttingen, Goettingen, Germany

11:30 AM

Board # 4007

Impact of Right Atrial Physiology on Heart Failure and Adverse Events After Myocardial Infarction

**Andreas Schuster** , Sören Jan Backhaus, Univ Med Göttingen, Goettingen, Germany; Thomas Stiermaier, Univ Heart Ctr L?beck, L?beck, Germany; Jenny-Lou Navarra, Univ Med Göttingen, Goettingen, Germany; Karl-Philipp Rommel, Herzzentrum Leipzig, Leipzig, Germany; Alexander Koschalka, Univ Med Göttingen, Goettingen, Germany; Johannes Kowallick, Univ Medical Ctr Göttingen, Goettingen; Joachim Lotz, Univ Med Göttingen, Goettingen, Germany; Boris Bigalke, Charite, Berlin, Germany; Shelby Kutty, Johns Hopkins Med, Baltimore, MD; Matthias Gutberlet, Heart Ctr Leipzig, Univ of Leipzig, Inst of Diagnostic and Interventional Radiology, Leipzig, Germany, Leipzig, Germany; Gerd Hasenfuss, Univ Med Göttingen, Goettingen, Germany; Holger Thiele, Univ Leipzig - Heart Ctr, Leipzig; Ingo Eitel, Univ Med Luebeck, Lübeck, Germany

11:30 AM

Board # 4008

Interplay of Infarct Territory Related Myocardial Mechanics and Prognostic Implications Following Acute Myocardial Infarction

Sören Jan Backhaus, Univ Med Göttingen, Goettingen, Germany; Johannes Kowallick, Univ Medical Ctr Göttingen, Goettingen; Thomas Stiermaier, Univ Heart Ctr L?beck, L?beck, Germany; Torben Lange, Univ Med Göttingen, Goettingen, Germany; Alexander Koschalka, Univ Med Göttingen, Göttingen, Germany; Jenny-Lou Navarra, Joachim Lotz, Univ Med Göttingen, Goettingen, Germany; Shelby Kutty, Johns Hopkins Med, Baltimore, MD; Boris Bigalke, Charite, Berlin, Germany; Matthias Gutberlet, Heart Ctr Leipzig, Univ of Leipzig, Inst of Diagnostic and Interventional Radiology, Leipzig, Germany, Leipzig, Germany; Hans-Josef Feistritzer, Heart Ctr Leipzig, Univ of Leipzig, Dept of Cardiology, Leipzig, Germany, Leipzig, Germany; Gerd Hasenfuss, Univ Med Göttingen, Goettingen, Germany; Holger Thiele, Univ Leipzig - Heart Ctr, Leipzig; Ingo Eitel, Univ Med Luebeck, Lübeck, Germany; **Andreas Schuster** , Univ Med Göttingen, Goettingen, Germany

11:30 AM

Board # 4009

Impact of Residual Coronary Atherosclerosis on Outcomes of Young Adults Following Myocardial Infarction: Results From Partner Young-MI Registry

**Junjie Yang** , David Biery, Brigham and Women's Hosp, Boston, MA; Avinainder Singh, Yale-New Haven Hosp, New Haven, CT; Sanjay Divakaran, Brigham and Women's Hosp, Boston, MA; Ersilia M Defilippis, NYP/Columbia Univ Medical Ctr, New York, NY; Arman Qamar, Brigham and Women's Hosp, Boston, MA; James L Januzzi, Massachusetts General Hosp, Wellesley Hills, MA; Jon Hainer, Brigham and Women's Hosp, boston, MA; Marcelo F DI CARLI, Deepak L Bhatt, Ron Blankstein, Brigham and Womens Hosp, Boston, MA

# Abstract Poster Session

## EA.APS.27 - Survival and Outcomes in ICD Patients

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2040

Outcomes Following Implantable Cardioverter Defibrillator Generator Replacement: A Systematic Review

**Killian J McCarthy** , Andrew Locke, Beth Israel Deaconess Medical Ctr, Boston, MA; Faisal Merchant, Emory Healthcare, Atlanta, GA; Daniel B Kramer, Beth Israel Deaconess Medical Ctr, Boston, MA

11:30 AM

Board # 2041

Long-Term Implantable Cardiac Rhythm Device Use in Heart Transplant Patients

Ashley Waring, George Mawardi, Amanda Northup, **Bhavadharini Ramu** , Adrian B VanBakel, Viswanathan Ramakrishnan, Medical Univ of South Carolina, Charleston, SC; Michael R Gold, Medical Univ South Carolina, Charleston, SC

11:30 AM

Board # 2042

Long-Term Clinical Outcomes in Young Patients With Hypertrophic Cardiomyopathy and Implantable Cardioverter-Defibrillators

**Austin Burrows** , Christopher Madias, Ethan J Rowin, Martin S Maron, Barry J Maron, Tufts Medical Ctr, Boston, MA

11:30 AM

Board # 2043

Predictors of One Year Survival After Implantable Cardioverter Defibrillator Implantation: Implications for Guidelines on Device Therapy

**Hassan Khan** , Emory Univ, Atlanta, GA; Marc Engels, Emory, Atlanta, GA; Stacy Westerman, Emory Univ, Atlanta, GA; Angel R Leon, Emory Univ Sch of Med, Atlanta, GA; Mikhael F El Chami, Faisal M Merchant, Emory Univ, Atlanta, GA

11:30 AM

Board # 2044

Impact of the Affordable Care Act on Implantable Cardioverter-Defibrillator Utilization in the United States: Findings From the National Cardiovascular Data Registry

**Christopher Madias** , Tufts Medical Ctr, Boston, MA; Craig Parzynski, Yale Univ Sch of Med, New Haven, CT; Austin Burrows, Tufts Medical Ctr, Boston, MA; Karl Minges, Jeptha Curtis, Yale Univ, New Haven, CT; Rami Doukky, Rush Medical Ctr, Chicago, IL

11:30 AM

Board # 2045

Feasibility of Meditation as Therapy for Improved Clinical Outcomes in Patients With Implantable Defibrillators

**Pankaj Malhotra** , Dali Fan, Nayereh Pezeshkian, Uma Srivatsa, UC Davis Medical Ctr, Sacramento, CA

11:30 AM

Board # 2046

Survival and Arrhythmia Risk in Medicare Patients With ICD Generator Changes in the NCDR ICD Registry Based on Left Ventricular Ejection Fraction at the Time of Generator Change

**Kenneth C Bilchick** , Univ of Virginia Health System, Charlottesville, VA; Yongfei Wang, Kumar Dharmarajan, Jeptha P Curtis, Yale Univ, New Haven, CT; Wayne Cecil Levy, Univ of Washington, Seattle, WA

11:30 AM

Board # 2047

Proportion of CIED Implantation and Incidence of Appropriate Therapy in Patients With Wild-Type Amyloidogenic Transthyretin Cardiac Amyloidosis

**Yusei Kawahara** , Kumamoto Univ Japan, kumamoto, Japan; Hisanori Kanazawa, Miwa Ito, Yusuke Kanemaru, Kumamoto Univ, Kumamoto, Japan; Takuya Kiyama, Kumamoto, Japan; Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

11:30 AM

Board # 2048

Novel Safe and Effective Role for Subcutaneous-ICDs in Patients With Hypertrophic Cardiomyopathy

**Nathaniel Steiger** , Austin Burrows, Ethan J Rowin, Christopher Madias, Tufts Medical Ctr, Boston, MA; Mark S Link, UTSouthwestern Medical Ctr, Dallas, TX; Barry J Maron, Minneapolis Heart Inst Foundat, Swampscott, MA; Martin S Maron, Tufts Medical Ctr, Boston, MA

11:30 AM

Board # 2049

Implantable Cardioverter Defibrillator Monotherapy and Congenital Long QT Syndrome: A Single Center's Experience

**Ciorsti Jean Macintyre** , QEII Health Sciences Ctr, Halifax, NS, Canada; John Giudicessi, Mayo Clinic, Rochester, MN; Johan Martijn Bos, Mayo Clinic Coll of Med, Rochester, MN; Michael John Ackerman, Mayo Clinic, Rochester, MN

11:30 AM

Poster Professor

Lee Eckhardt

# Abstract Poster Session

## AC.APS.11 - Tools for Predicting and Modifying Cardiovascular Risk

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 4041

Derivation and External Validation of a High Sensitivity Troponin Based Proteomic Model to Predict the Presence of Obstructive Coronary Artery Disease

**Cian P. McCarthy** , Massachusetts General Hosp, Boston, MA; Johannes Tobias Neumann, Univ Heart Ctr, Hamburg, Germany; Sam A. Michelhaugh, Nasrien E. Ibrahim, Hanna K Gaggin, Massachusetts General Hosp, Boston, MA; Nils A. Sörensen, Univ Heart Ctr, Hamburg, Germany; Craig A. Magaret, Grady Barnes, Rhonda Fay Rhyne, Prevencio, Inc, Kirkland, WA; Dirk Westermann, Univ Heart Ctr, Hamburg, Germany; James L Januzzi, Massachusetts General Hosp, Wellesley Hills, MA

11:30 AM

Board # 4042

Outcomes After Noninvasive Cardiac Testing Compared to Clinical Evaluation Alone in Stable Chest Pain Patients - A Secondary Analysis of the Promise Randomized Clinical Trial

**Getu Teressa** , Yun Ling, Stony Brook Med, Stony Brook, NY; Andreas P Kalogeropoulos, Stony Brook Univ, Stony Brook, NY; Michael Poon, Mt. Sinai Medical Ctr, NY

11:30 AM

Board # 4043

Use of the Precise-DAPT Score to Predict Mortality in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention

**Anum Asif** , Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Ahmet Sezer, Floyd Thoma, Univ of Pittsburgh Medical Ctr, PITTSBURGH, PA; Catalin Toma, John Schindler, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Jeffrey Fowler, Conrad Smith, Oscar C Marroquin, Univ of Pittsburgh Medical Ctr, PITTSBURGH, PA; Suresh Mulukutla, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA

11:30 AM

Board # 4044

Are High Intensity Statins Beneficial in Patients With "High Intensity Like" LDL-C Reduction on Low Dose Statin: Insights From the TNT Trial

**Sripal Bangalore** , New York Univ Sch of Med, New York, NY; Rana Fayyad, Pfizer Inc., New York, NY; David A DeMicco, Pfizer, New York, NY; David D Waters, UCSF, San Francisco, CA

11:30 AM

Board # 4045

Which Vessel is Preferred to Initiate Spasm Provocation Test: Right or Left Coronary Artery?

**Hiroki Teragawa** , Chikage Oshita, Yuichi Orita, JR Hiroshima Hosp, Hiroshima, Japan

11:30 AM

Board # 4046

Cardiovascular Outcomes in Patients With Coexisting Coronary Artery Disease and Inflammatory Bowel Disease

**Temidayo Abe** , Taiwo Ajose, Ngum Nkikah Atem, Valery S Effoe, Morehouse Sch of Med, Atlanta, GA

11:30 AM

Board # 4047

Increased Inflammatory Monocytes in South Asians at Risk for Coronary Atherosclerosis

**Krishnan Ramanathan** , St. Paul's Hosp, Vancouver, BC, Canada; Christopher Franco, Royal Jubilee Hosp, Victoria, BC, Canada; Stephanie Sellers, Beth Whalen, Kapilan Selvakumar, St. Paul's Hosp, Vancouver, BC, Canada; Hamed Nazzari, Omid Kiamanesh, Thomas Rolston, UBC, Vancouver, BC, Canada; Carolyn M Taylor, Univ of British Columbia, Vancouver, BC, Canada; Jonathon Leipsic, St. Paul's Hosp, Vancouver, BC, Canada

11:30 AM

Board # 4048

Effect of Angiotensin Converting Enzyme Inhibitors in Stable Coronary Artery Disease With Mid-Range Ejection Fraction

**Abhinav Sood** , Mount Sinai Beth Israel, New York, NY; Wai Hong Wilson Tang, Cleveland Clinic, Cleveland, OH

11:30 AM

Board # 4049

Cardiac Troponin I Measured With a Single Molecule Counting Assay for Ruling Out Coronary Artery Disease in Patients With Stable Chest Pain

**Sjur H Tveit** , Akershus Univ Hosp, Lorenskog, Norway; Peder L Myhre, Akershus Univ Hosp, Oslo, Norway; Tove Aminda Hanssen, Signe H Forsdahl, Amjid Iqbal, Univ Hosp of North Norway, Tromso, Norway; Torbjørn Omland, Henrik Schirmer, Akershus Univ Hosp, Lorenskog, Norway

11:30 AM

Poster Professor

E Magnus Ohman, Durham, NC

# Abstract Poster Session

## CH.APS.17 - Valves and Thrombosis

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 4129

Primary Mechanisms of Early Valve Failure Are Accurately Identified by 3D Echocardiography With Excellent Results for Early Re-Repair If Dehisced Sutures or Leaflet Tears Identified

**Sachie Shigemitsu** , Norazah Zahari, Mirza Beigh, Amal Silmi, Amol Moray, Lily Lin, Timothy M Colen, Viljee Jonker, Darren H Freed, Ivan M Rebeyka, David Ross, Mohammed Al-Aklabi, Nee Scze Khoo, Stollery Children's Hosp, Univ of Alberta, Edmonton, AB, Canada

11:30 AM

Board # 4130

Tricuspid Valve (TV) Adaptive Changes to Chronic Right Ventricular (RV) Pressure and Volume Stressors in a Piglet Model Suggest Rapid Increase in Collagen Content: A Pilot Study

**Lily Q Lin** , Univ of Alberta, Stollery Children's Hosp, Edmonton, AB, Canada; Taisiya Sigaeva, Ziad Abu Sara, Univ of Calgary, Calgary, AB, Canada; Sanaz Hatami, Consolato Sergi, Univ of Alberta, Edmonton, AB, Canada; Elena S Di Martino, Univ of Calgary, Calgary, AB, Canada; Walter Herzog, Univ of Calgary, Edmonton, AB, Canada; Richard Thompson, James Y Coe, Timothy M Colen, Darren H Freed, Nee Scze Khoo, Univ of Alberta, Edmonton, AB, Canada

11:30 AM

Board # 4131

Prophylactic Medical Therapy in Young Patients With Severe Bicuspid Aortopathy

**Jonathan N. Flyer** , Univ of Vermont, Burlington, VT; Lynn A Sleeper, Boston Childrens Hosp, Boston, MA; Steven D Colan, Boston Children's Hosp, Boston, MA; Michael N Singh, Ronald V Lacro, Boston Childrens Hosp, Boston, MA

11:30 AM

Board # 4132

Aortic Stiffening is More Rapid in Bav Than in Genetic Aortopathies and is Associated With Rate of Aortic Dilation

Alejandro Perez Casares, Boston Children's Hosp, Boston, MA; Kimberlee Gauvreau, Audrey Dionne, **Ashwin Prakash** , Boston Childrens Hosp, Boston, MA

11:30 AM

Board # 4133

Direct Measurement of Atrioventricular Valve Regurgitant Jets is Accurate and Reliable for Patients With Congenital Heart Disease

**Kimberley Jacobs** , Lucile Packard Children's Hosp, Stanford, Sch of Med, Palo Alto, CA; Joseph Rigdon, Frandics Chan, Joseph Y Cheng, Marcus T Alley, Stanford Univ, Sch of Med, Palo Alto, CA; Shiraz A Maskatia, Lucile Packard Children's Hosp, Stanford Univ, Sch of Med, Palo Alto, CA; Shreyas Vasanawala, Stanford Univ, Sch of Med, Palo Alto, CA

11:30 AM

Board # 4134

The Trajectory of Left Ventricular Remodeling in Children With Valvar Aortic Stenosis After Balloon Aortic Valvuloplasty

**Koyelle Papneja** , Stanford Univ, PALO ALTO, CA; Zachary Blatman, Ian D Kawpeng, Jacqueline Wheatley, Hanne Oscé, Boning Li, Myriam Lafreniere-Roula, Chun Po Steve fan, Cedric Manlhiot, Lee Benson, Luc Mertens, The Hosp for Sick Children, Toronto, ON, Canada

11:30 AM

Board # 4135

Effect of Pulmonary Valve Replacement on Function and Right Ventricular Volume by Cardiac Magnetic Resonance Imaging in Patients With Repaired Tetralogy of Fallot

**Sarah E Kollar** , Connecticut Children's Medical Ctr, Hartford, CT; Berthold Klas, TomTec Corp, Corrales, NM; Maua H Mosha, Alexandra T Channing, Connecticut Children's Medical Ctr, Hartford, CT; Steven Walling, Trinity Health of New England Saint Francis Hosp and Medical Ctr, Hartford, CT; Olga H Toro-Salazar, Connecticut Childrens Medical Ctr, Hartford, CT

11:30 AM

Board # 4136

Innovative Online Warfarin Education is Demonstrated to be Successful for Patients Initiating Warfarin: Flying With the eKITE (electronic Kidclot Interactive Thrombosis Education) Study

**Mary Bauman** , Stollery Childrens Hosp, Edmonton, AB, Canada; Christina Juliana VanderPluym, Boston Childrens Hosp, Boston, MA; Ewurabena Simpson, Childrens Hosp of Eastern Ontario, Ottawa, ON, Canada; Mary Mehegan, St Louis Childrens Hosp, St Louis, MO; Stefan Kuhle, Izaak Walter Killam Hosp, Halifax, NS, Canada; Suzanne Siddons, Stollery Childrens Hosp, Edmonton, AB, Canada; Patty Knox, Alberta Childrens Hosp, Calgary, AB, Canada; Heather Soni, Texas Childrens Hosp, Houston, TX; Aisha Bruce, M Patricia Massicotte, Stollery Childrens Hosp, Edmonton, AB, Canada

11:30 AM

Board # 4137

Risk Factors for Bleeding in Children With Acquired and Congenital Heart Disease Treated With Warfarin

**Paul Esteso** , Beth Hawkins, Courtney Ventresco, Amy Hellinger, Austin Liou, Lynn A Sleeper, Jesse Esch, Elizabeth Blume, Boston Children's Hosp, Boston, MA; Christina Juliana VanderPluym, Boston Childrens Hosp, Boston, MA

11:30 AM

Board # 4138

The Cost Of Clot: Resource Utilization and Outcomes in Children With Thrombosis After Cardiac Surgery

**Jason T Patregnani** , Children's Natl Health System, Washington, DC; Lina Lander, Univ of California San Diego, San Diego, CA; Pranava Sinha, Children's Natl Medical Ctr, Washington, DC; Rahul Shah, Children's Natl Health System, Washington, DC

11:30 AM

Poster Professor

DANIEL Penny, Houston, TX

# Abstract Poster Session

## HF.APS.39 - Valvular Heart Disease Outcomes

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2242

Long Term Prognostic Value of Right Bundle Branch Block in Severe Aortic Regurgitation: Outcome in 756 Patients Over 20 Years

**Balaji Natarajan** , UC Riverside Sch of Med, San Bernardino, CA; Srishti Nayak, Loma Linda Univ Medical Ctr, Loma linda, CA; Padmini Varadarajan, Loma Linda Univ Med Ctr, Redlands, CA; Ramdas G Pai, Univ of California Riverside Sch of Med, Riverside, CA

11:30 AM

Board # 2243

High Prevalence of Aortic Valve Stenosis in Patients With ST-Segment Elevation Myocardial Infarction

**Gurpreet K Singh** , Laurien Goedemans, E. Mara Vollema, Rachid Abou, Nina Ajmone Marsan, Jeroen J Bax, Victoria Delgado, Leiden Univ Medical Ctr, Leiden, Netherlands

11:30 AM

Board # 2244

Clinical Outcomes and Predictors for Adverse Cardiac Events in Medically Treated Patients With Atrial Mitral Regurgitation

**Kitae Kim** , Misun Pak, Toshiaki Toyota, Yasuhiro Sasaki, Takeshi Kitai, Atsushi Kobori, Natsuhiko Ehara, Makoto Kinoshita, Shuichiro Kaji, Yutaka Furukawa, Kobe City Medical Ctr General Hosp, Kobe, Japan

11:30 AM

Board # 2245

Predicting Progression of Mitral and Tricuspid Regurgitation, a Multidecade Echocardiographic Study

**Jordan B Strom** , Richard A. and Susan F. Smith Ctr for Outcomes Res in Cardiology, Boston, MA; Patrick Hyland, Beth Israel Deaconess Medical Ctr, Boston, MA; Yuansong Zhao, Changyu Shen, Richard A. and Susan F. Smith Ctr for Outcomes Res in Cardiology, Boston, MA; Lawrence J Markson, Beth Israel Deaconess Medical Ctr, Boston, MA; Dhruv S Kazi, Richard A. and Susan F. Smith Ctr for Outcomes Res in Cardiology, Beth Israel Deaconess Medical Ctr, Boston, MA; Warren J Manning, Beth Israel Deaconess Medical Ctr, Boston, MA

11:30 AM

Board # 2246

Is Gender a Key Determinant of Exercise Tolerance in Moderate-to-Severe Aortic Stenosis?

**Francesco Bandera** , Greta Ghizzardi, Valentina Milani, IRCCS Policlinico San Donato, Milano, Italy; Sara Boveri, IRCCS Policlinico San Donato, San Donato Milanese, Italy; Eleonora Alfonzetti, Cardiology Univ Dept, Milano, Italy; Marco Guazzi, IRCCS Policlinico San Donato, Milano, Italy

11:30 AM

Board # 2247

Risk Stratification of Clinical Outcomes Using Laboratory Biomarkers in Patients With Severe Tricuspid Regurgitation: The Prognostic Impact of Blood Urea Nitrogen

**Shoko Nakagawa** , Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Hiroyuki Takahama, Natl Cardiovascular Ctr, Suita, Japan; Yoshiki Yanagi, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Yasuhiro Hamatani, Natl Cerebral and Cardiovascular Ct, Osaka, Japan; Masashi Amano, Atsushi Okada, Makoto Amaki, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Takuya Hasegawa, Natl Cerebal & Cardiovascular Ctr, Suita Osaka, Japan; Hideaki Kanzaki, Natl Cardiovascular Ctr, Osaka, Japan; Kunihiro Nishimura, NCVC, Suita, Japan; Satoshi Yasuda, Natl Cereb Cardiovascular Ctr, Osaka, Japan; Chisato Izumi, Natl Cerebral and Cardiovacular, Suita, Japan

11:30 AM

Board # 2248

Lower Myocardial Energetic Efficiency is Associated With Increased Cardiovascular Risk in Asymptomatic Aortic Valve Stenosis

**Edda B Bahlmann** , Asklepios Clinic St. Georg, Hamburg, Germany; Sahrai Saeed, Haukeland Univ Hosp, Hamburg, Germany; John Chambers, Guys and St. Thomas Hosp, London, United Kingdom; Eigir Einarsen, Univ of Bergen, Bergen, Norway; Dana Cramariuc, Haukeland Univ Hosp, Bergen, Norway; Anne Rossebø, Oslo Univ Hosp, Oslo, Norway; Karl Heinz Kuck, Asklepios Clinic St. Georg, Hamburg, Germany; Eva Gerdts, Univ of Bergen, Bergen, Germany

11:30 AM

Board # 2249

Which Classification Scheme of Bicuspid Aortic Valve Can Predict Aortopathy ─ Sievers, Dichotomous or Raphe?

**Yi-Jia Li** , Wei-Guo Ma, Yue Qi, Jun-Ming Zhu, Ya Yang, Li-Zhong Sun, Beijing Anzhen Hosp, Beijing, China

11:30 AM

Board # 2250

Determinants and Prognostic Implications of Aortic Stenosis in Patients With Mild Coronary Artery Disease

**Kyohei Onishi** , Heitaro Watanabe, Kindai Univ Faculty of Med, Osakasayama, Japan; Masakazu Yasuda, Kindai Univ, Oosakasayama, Japan; Kenji Yamaji, Kindai Univ. Faculty of Med, Osakasayama, Japan; Masafumi Ueno, Yoshitaka Iwanaga, Kindai Univ Faculty of Med, Osakasayama, Japan

11:30 AM

Board # 2251

Prognosis and Prognostic Predictors of Atrial Functional Mitral Regurgitation; In Comparison With Ventricular Functional Mitral Regurgitation

**Chisato Okamoto** , Atsushi Okada, Yasuhiro Hamatani, Masashi Amano, Hiroyuki Takahama, Makoto Amaki, Takuya Hasegawa, Hideaki Kanzaki, Tomoyuki Fujita, Junjiro Kobayashi, Satishi Yasuda, Chisato Izumi, Natl Cerebral and Cardiovascular Ctr, Suita, Japan

# Abstract Poster Session

## IM.APS.13 - Vascular Imaging

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 4202

Neurobiological Resilience Associates With a Reduced Risk of MACE

**Tawseef Dar** , Massachusetts General Hosp, Boston, MA; Shady Abohashem, Massachusetts General Hosp-HMS, Revere, MA; Ahmed Ghoneem, Nicki Naddaf, Michael T. Osborne, Ahmed A Tawakol, Massachusetts General Hosp, Boston, MA

11:30 AM

Board # 4203

Evaluation of Glucose Metabolic Activity of Carotid Artery Plaque Components: A Structural-Functional Assessment Using PET-MRI

**William B Reichert** , Diane Parrington, Carl T Hayden Va Medical Ctr, Phoenix, AZ; Edwin Goldstein, Carl T Hayden Va Medical Ctr, Phoeinix, AZ; Keith Chan, Julie Kurtz, Raymond Q Migrino, Carl T Hayden Va Medical Ctr, Phoenix, AZ

11:30 AM

Board # 4204

Carotid Plaque Lipid Content is Reduced After 6 Months of Proprotein Convertase Subtilisin Kexin Type 9 Inhibition With Alirocumab: an Interim Analysis of a Serial Magnetic Resonance Imaging Study

Jie Sun, Univ of Washington, Seattle, WA; **Norman E Lepor** , Westside Medical Associates LA, Beverly Hills, CA; Gador Canton, Univ of Washington, Seattle, WA; Laurn Contreras, Westside Medical Associates of Los Angeles, Beverly Hills, CA; Daniel S Hippe, Daniel Isquith, Univ of Washington, Seattle, WA; Niranjan Balu, Univ of Washington, Redmond, WA; Ilan Kedan, Cedars-Sinai Heart Inst, Los Angeles, CA; Americo Simonini, Cedars Sinai, Los Angeles, CA; Chun Yuan, Xue-Qiao Zhao, Thomas S Hatsukami, Univ of Washington, Seattle, WA

11:30 AM

Board # 4205

Undernourishment and Atherosclerosis: A Study of Carotid Plaque and Aortic Calcification With Outcomes

**Shih-Chieh Chien** , MacKay Memorial Hosp, Taipei, Taiwan; Chun-Ho Yun, Chung-lieh Hung, Hung-I Yeh, Mackay Memorial Hosp, Taipei, Taiwan

11:30 AM

Board # 4206

Echolucency of Carotid Plaque is Useful for Selecting High-risk Patients With Chronic Coronary Artery Disease

**Manabu Uematsu** , Takamitsu Nakamura, Juntaro Deyama, Takeo Horikoshi, Aki Kobayashi, Toru Yoshizaki, Yosuke Watanabe, Tsuyoshi Kobayashi, Daisuke Fujioka, Yukio Saito, Kazuto Nakamura, Kenichi Kawabata, Jun-ei Obata, Kiyotaka Kugiyama, Yamanashi Univ, Chuo, Japan

11:30 AM

Board # 4207

Aortic Valve Imaging in Aortic Stenosis - A Network and Pairwise Meta-analysis

**Lisa Q. Rong** , Weill Cornell Med, New York, NY; Irbaz Hameed, New York Presbyterian Weill Cornell, New York, NY; Antonino Di Franco, Weill Cornell Medical Coll, New York, NY; Mohamed Rahouma, Faiza Khan, Richard B Devereux, Mario Gaudino, Weill Cornell Med, New York, NY

11:30 AM

Board # 4208

Maltohexaose-indocyanine Green (mh-icg) for Near Infrared Imaging of Bacterial Endocarditis

**Kiyoko Takemiya** , Emory Univ, Atlanta, GA; Joachim J Roeise, Maomao He, Chung Taing, UC Berkeley, Berkeley, CA; Alexander G Rodriguez, Emory Univ, Atlanta, GA; Niren Murthy, UC Berkeley, Berkeley, CA; Mark M Goodman, Emory Univ, Atlanta, GA; William Robert Taylor, Emory Univ Sch of Med, Atlanta, GA

11:30 AM

Board # 4209

Evaluation Method of Pulmonary Perfusion by Sequential Radiography : Preliminary Study in Monkey

**Hidemitsu Miyatake** , Fujino Kazunori, Tabata Tosihisa, Shiga Univ of Medical Science, Ootu, Japan; Yasuyuki Tsujita, Yutaka Eguchi, Shiga Univ of Medical Science, Otsu, Japan

11:30 AM

Board # 4210

Comparison of Syntax Score and Calcification Score in Prognosis of Patients With Peripheral Artery Disease

**Tatsunori Noto** , Ota Memorial Hosp, Gunma, Japan; Naohiko Nemoto, Ota Memorial Hosp, Ota, Japan

11:30 AM

Board # 4211

Long-term Treatment With Linagliptin Provides Multiple Ultrasonic-evaluated Antiatherosclerotic Effects Independent of Diabetic Improvement for Type-2 Diabetics Receiving Statin

**Tatsuaki Murakami** , Kazuo Ohsato, Fukui Cardiovascular Ctr, Fukui, Japan

# Abstract Poster Session

## EA.APS.24 - Ventricular Arrhythmias Risk Factor Evaluation and Predictors

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 2010

Heart Failure With Preserved Ejection Fraction Manifesting With Shockable Cardiac Arrest: Implications for Prevention of Sudden Death

**Orison O Woolcott** , Kyndaron Reinier, Audrey Uy-Evanado, Cedars-Sinai Medical Ctr, Los Angeles, CA; Gregory A Nichols, Kaiser Permanente, Portland, OR; Eric Stecker, Knight Cardiovascular Inst, Portland, OR; Jonathan Jui, OHSU, Wilsonville, OR; Sumeet S Chugh, Cedars-Sinai Medical Ctr, Los Angeles, CA

11:30 AM

Board # 2011

Outcomes After Ventricular Tachycardia/Fibrillation Presentation Among Patients With Spontaneous Coronary Artery Dissection

**Christopher Cheung** , Andrew Starovoytov, Ashkan Parsa, Jason Andrade, Andrew Krahn, Matthew Bennett, Jacqueline Saw, Univ of British Columbia, Vancouver, BC, Canada

11:30 AM

Board # 2012

Subgroup of Ventricular Fibrillation With a Different Mechanism of Initiation in Implantable Defibrillator Recipients

**Eric Xie** , Johns Hopkins Univ Sch of Med, Baltimore, MD; Katrina Mayer, Johns Hopkins Univ, Baltimore, MD; Melissa F Capps, Johns Hopkins Univ Sch of Med, Baltimore, MD; Andreas S Barth, Johns Hopkins Univ, Baltimore, MD; Charles Love, Johns Hopkins Univ Sch of Med, Baltimore, MD; Ruben Coronel, Medical and Biological Engineering, Amsterdam, AZ; Hiroshi Ashikaga, Johns Hopkins Univ Sch of Med, Baltimore, MD

11:30 AM

Board # 2013

Improving Arrhythmic Risk Stratification in Non-Ischemic Dilated Cardiomyopathy Through the Evaluation of Novel Scar Characteristics Using CMR

**Brian P Halliday** , Imperial Coll, London, London, United Kingdom; Gabriel Balaban, Kings Coll London, London, United Kingdom; Caroline Mendonca Costa, King's Coll London, London; Wenjia Bai, Imperial Coll, London, London, United Kingdom; Bradley Porter, Stoke Mandeville Hosp, Buckinghamshire Healthcare Trust, Princes Risborough, United Kingdom; Suzan Hatipoglu, Royal Brompton Hosp, London, United Kingdom; Nuno Dias Fereira, Imperial Coll, London, London, United Kingdom; Cemil Izgi, Royal Brompton Hosp, London, United Kingdom; Ben Corden, Duke, Singapore, Singapore; Upasana Tayal, Royal Brompton Hosp, London; James Simon Ware, Imperial Coll London, London; Gernot Plank, Univ of Graz, Graz, Austria; C. Aldo Rinaldi, St. Thomas's Hosp, London, United Kingdom; Daniel Rueckert, Imperial Coll, London, London, United Kingdom; Sanjay Kumar Prasad, Royal Brompton Hosp, London, United Kingdom; Martin Bishop, Kings' Coll London, London, United Kingdom

11:30 AM

Board # 2014

Reappraisal of Electrocardiographic Criteria for Localization of Idiopathic Outflow Tract Ventricular Arrhythmias With Left Bundle Branch Block and Inferior Axis Morphology

**Mohamed Mahfouz Amin Abdelrahman** , NewYork-Presbyterian/Weill Cornell Medical Ctr, New York, NY; Guillaume Bassil, New York Presbyterian Weill Cornell, New York, NY; Christopher F Liu, Weill Cornell Medical Coll, New York, NY; James E Ip, Weill Cornell Medical Ctr, New York, NY; George Thomas, Cornell Univ Medical Coll, New York, NY; Steven Markowitz, Weill Cornell Medical Coll, New York, NY; Bruce B Lerman, Weill Med Cornell Univ, New York, NY; Jim W Cheung, Weill Cornell Medical Coll, New York, NY

11:30 AM

Board # 2015

Circulating Mir-223-3p As A Novel Biomarker And Pathogenesis Of Brugada Syndrome

**Yukiko Nakano** , Yuko Onohara, Chikaaki Motoda, Takehito Tokuyama, Naoya Hironobe, Yousaku Okubo, sho okamura, Shunsuke Miyauchi, Yoshihiro Ikeuchi, Orie Nishiyama, Hidenori Ochi, Kazuaki Chayama, Yasuki Kihara, Hiroshima Univ, Hiroshima, Japan

11:30 AM

Board # 2016

Characterization of Young Patients With Catecholaminergic Polymorphic Ventricular Tachycardia Based on Age at Presentation

**Dania Kallas** , Sonia Franciosi, Thomas M Roston, BC Children's Hosp, Vancouver, BC, Canada; Krystien V Lieve, Amsterdam Medical Ctr, Amsterdam, Netherlands; Sit Yee Kwok, Queen Mary Hosp, Hong Kong, Hong Kong; Linda Knight, Sibley Heart Ctr, Atlanda, GA; Prince J Kannankeril, Vanderbilt Univ Medical Ctr, Nashville, TN; Allison Hill, Children's Hosp Los Angeles, Los Angeles, CA; Andrew D Krahn, Univ of British Columbia, Vancouver, BC, Canada; Martin J LaPage, Univ of Michigan, Ann Arbor, MI; Susan P Etheridge, Univ of Utah, Salt Lake City, UT; Ian H Law, Univ of Iowa Hosp, Iowa City, IA; Seshadri Balaji, Oregon Health Science Univ, Portland, OR; Christopher L Johnsrude, Univ of Louisville, Louisville, KY; David Backhoff, Univ of Gottingen, Gottingen, Germany; Svjetlana Tisma-Dupanovic, Children's Mercy Hosp, Kansas City, KS; Joseph Atallah, Stollery Children's Hosp, Edmonton, AB, Canada; James C Perry, Rady Children's Hosp, San Diego, CA; Adam C Kean, Indiana Univ Sch of Med, Indianapolis, IN; Georgia Sarquella-Brugada, Hosp Sant Joan de Deu, Barcelona, Spain; Joshua R Kovach, Children's Hosp of Wisconsin, Milwaukee, WI; Anna N Kamp, Nationwide Children's Hosp, Columbus, OH; Peter Aziz, Cleveland Clinic, Cleveland, OH; Yung R Lau, Univ Alabama Birmingham, Birmingham, AL; Jordana Kron, Virginia Commonwealth Univ, Richmond, VA; Arthur A Wilde, Amsterdam Medical Ctr, Amsterdam, Netherlands; Shubhayan Sanatani, BC Children's Hosp, Vancouver, BC, Canada

11:30 AM

Board # 2017

Predictors of Post-myocardial Infarction Sudden Cardiac Arrest Among Patients With Ejection Fraction Greater Than 35%: the THRED Variables

**Selcuk Adabag** , Minneapolis VA Medical Ctr, Minneapolis, MN; Patrick Zimmerman, Medtronic, Mounds View, MN; Dan Lexcen, Medtronic, Mounds view, MN; Alan Cheng, Medtronic, Mounds View, MN

11:30 AM

Board # 2018

Predicting Sudden Cardiac Death Risk in Heart Failure With Preserved Ejection Fraction

**Selcuk Adabag** , Minneapolis VA Medical Ctr, Minneapolis, MN; Lisa Langsetmo, Univ of Minnesota, Minneapolis, MN

11:30 AM

Poster Professor

Rhea C Pimentel, Kansas City, KS

11:30 AM

Board # 2019

Real World Data of Fatal Events Within One Year After Initiating Adaptive Servo Ventilation Therapy in Patients With Heart Failure With Reduced Ejection Fraction

**Atsushi Umeyama** , Gunma Univ Sch of Med, Maebashi, Japan

# Abstract Poster Session

## AC.APS.09 - Where Did The Thrombus Come From?

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

11:30 AM

Board # 4021

Double Trouble: A Case of St-segment-elevation Myocardial Infarction in a Patient With Vasculitis

**Mohsin Chowdhury** , Beth Israel Deaconess Medical Ctr, Boston, MA; David Dobroski, South Shore Hosp, South Weymouth, MA; Diana Esther Litmanovich, Brett Carroll, Beth Israel Deaconess Medical Ctr, Boston, MA

11:30 AM

Board # 4022

Bleeding Ventriculo-Cutaneous Fistula After a Traumatic Dissection of the Left Anterior Descending Coronary Artery, Acute Coronary Syndrome and Secondary Infected Ventricular Aneurysm

**Sebastian Gallo-Bernal** , Andres Felipe Salinas, Andrea Carolina Castillo, Carlos Obando, Hector M Medina, Julian Francisco Forero, Fundacion Cardioinfantil, Bogota, Colombia

11:30 AM

Board # 4023

A Case of Myocardial Ischemia - Plumbing or Electrical Disorder

**Subhashish Agarwal** , Medical Coll of Wisconsin/Froedert Community Memorial Hosp, Wood Dale, IL; Sachin Goel, St Johns Hosp, Springfield, IL

11:30 AM

Board # 4024

Giant Coronary Artery Aneurysms: An Unusual Case of STEMI

**Harshith S Thyagaturu** , Farah Deshmukh, Sandeep Mangalmurti, Bassett Medical Ctr, Cooperstown, NY

11:30 AM

Board # 4025

Cor-triatriatum Dextrum and Patent Foramen Ovale: A Rare Co-occurrence Leading to Recurrent Strokes

**Sohaib S Roomi** , Zain Ali, Waqas Ullah, Artem Minalyan, Shujaul Haq, Abington Hosp-Jefferson Health, Abington, PA; Mahnoor Shirazi, Fndn Univ Medical Coll, Rawalpindi, Pakistan

11:30 AM

Board # 4026

Concomitant Presentation With Cardioembolic Ischemic Stroke and Non St Elevation Myocardial Infarction in a Patient With New Onset Atrial Fibrillation

**Amogh Joshi** , Emilee Kurtz, Fnu Vikram, Kourtney Erickson, Margaret Kluck, Benjamin Sanchez, Lehigh Valley Health Network, Allentown, PA

11:30 AM

Board # 4027

A Rare Case of Culture Negative Bartonella Endocarditis Resulting in Septic Coronary Embolism Presenting as ST Segment Elevation Myocardial Infarction

**Jonathan Nattiv** , Hussain Basrawala, Jennifer Tang, Anil Mehra, David Shavelle, LAC+USC Medical Ctr, Los Angeles, CA

11:30 AM

Board # 4028

Endocardial Metastasis of Urothelial Carcinoma Masquerading as ST-segment Elevation Myocardial Infarction

**Gary S Ma** , Quan M. Bui, Lori Daniels, UC San Diego, La Jolla, CA

11:30 AM

Board # 4029

Left Main Coronary Embolism in Association With Ostium Secundum Atrial Septal Defect Presenting as Acute Coronary Syndrome

**Omar S AL-Taweel** , Tareq Abu Sharifeh, Mohamed F Almahmoud, Syed Gilani, Loui Rejjal, Murtaza Mazhar, Rafic F Berbarie, Univ of Texas Medical Branch, Galveston, TX

11:30 AM

Poster Professor

Savitri Fedson, Houston, TX

11:30 AM

Board # 4030

Lithium Toxicity Presenting as 2:1 Atrioventricular Block

**Jin Ei Chan** , Voravech Nissaisorakarn, Michael J Grushko, Jacobi Medical Ctr / Albert Einstein Coll of Med, Bronx, NY

# Simulation

## SIM.18 - Cases in Valvular Heart Disease, Adult Congenital Heart Disease, and Arrhythmias

#### Simulation Zone - Heart Hub, Hall C

### Monday, November 18, 2019, 11:30 AM - 12:00 PM

1:00 PM

Invited Presenter

Tina Baykaner, Palo Alto, CA

# Expert Theater

## ET.26 - Amarin Pharma, Inc.

#### Learning Studio 2, Booth # 7

### Monday, November 18, 2019, 12:00 PM - 12:45 PM

This is not a CME/CE certified session

# Expert Theater

## ET.27 - Pfizer

#### Learning Studio 1, Booth # 5

### Monday, November 18, 2019, 12:00 PM - 12:45 PM

This is not a CME/CE certified session

# Council Sponsored Activities

## CSA.02 - ATVB Council Luncheon & Annual Business Meeting

#### Philadelphia Marriott Downtown hotel, room Franklin 2/3/4

### Monday, November 18, 2019, 12:15 PM - 1:30 PM

This is not a CME/CE certified session

# Hall

## EP.HT.07 - Tackling Challenging Atrial Arrhythmias in the EP Lab - Tips and Pearls from the Experts

#### EP Central

### Monday, November 18, 2019, 12:30 PM - 1:15 PM

12:30 PM

Moderator

Arun Mahankali Sridhar, Seattle, WA

12:30 PM

Panel Participant

Joshua M Cooper, Philadelphia, PA

# Abstract Rapid Fire Oral

## CA.RFO30 - Big Love, Big Myocytes

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 12:40 PM - 1:30 PM

12:40 PM

Moderator

Shirin Doroudgar, Heidelberg, Germany

12:40 PM

Cardiac-specific Abrogation of NF-kB Activation Ameliorates Pressure Overload-induced Left Ventricular Hypertrophy and Dysfunction

**Guangming Cheng** , Lin Zhao, Magdy Girgis, Univ of Nevada, Las Vegas, Las Vegas, NV; Arash Davani, Natl Endocrinological and Diabetes Inst, Ľubochňa, Slovakia; Yanjuan Yang, Jeryl Hauptman, Buddhadeb Dawn, Univ of Nevada, Las Vegas, Las Vegas, NV

12:45 PM

Q & A

12:50 PM

Spliced X-Box Binding Protein 1 Stimulates Adaptive Growth Through Activation of MTOR

**Xiaoding Wang** , UT Southwestern Medical Sch, Dallas, TX; Zhao Wang, UT Southwestern Medical Ctr, Dallas, TX

12:55 PM

Q & A

1:00 PM

GTP-binding Protein 9 Inhibition Attenuates Hypertrophic Response in Human Ventricular Myocytes

Gayathri Narasimhan, **Mallikarjun Patil** , Hien T Luong, John Henderson, Prasanna Krishnamurthy, Univ of Alabama at Birmingham, Birmingham, AL

1:05 PM

Q & A

1:10 PM

Role of Rho Effector Mdia1 Signaling to Maintain Cardiac Function in Response to Pressure Overload in Mice

**Ichitaro Abe** , Takeshi Terabayashi, Toshimasa Ishizaki, Naohiko Takahashi, Oita Univ, Oita, Japan

1:15 PM

Q & A

1:20 PM

A Kinase Interacting Protein 1 (AKIP1) Promotes Physiological Cardiac Remodeling

**Kirsten T. Nijholt** , Harmen G. Booij, Rudolf A De Boer, Silke U. Oberdorf-Maass, Mario G. Pavez Giani, Wiek H. van Gilst, Herman H.W. Silljé, B. Daan Westenbrink, Univ Medical Ctr Groningen, Groningen, Netherlands

1:25 PM

Q & A

# Abstract Rapid Fire Oral

## PH.RFO33 - Emerging Mechanisms of Pulmonary Vascular Remodeling and Homeostasis

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 12:40 PM - 1:30 PM

12:40 PM

Moderator

Hyung J Chun, New Haven, CT

12:40 PM

Skeletal Muscle LKB1/SIRT3-AMPK-GLUT4 Activation by Treprostinil and Metformin Normalizes Hyperglycemia and Improves Cardiac Function in Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction (PH-HFpEF)

Longfei Wang, VMI, Univ of Pittsburgh, Pittsburgh, PA; Taijyu Satoh, Pittsburgh university, Pittsburgh, PA; Gunner Halliday, Indiana Univ, Indianapolis, IN; Jeff Baust, Univ of Pittsburgh, Pittsburgh, PA; Rebecca Vanderpool, The Univ of Arizona, Tucson, AZ; Ana Lucia Mora, Univ of Pittsburgh, Pittsburgh, PA; Mark T Gladwin, Univ Pittsburgh, Pittsburgh, PA; **Yen Chun Lai** , Indiana Univ, Indianapolis, IN

12:50 PM

Endothelial Frataxin Deficiency Drives DNA Damage Response and Senescence in Pulmonary Hypertension

**Miranda Kay Culley** , Univ of Pittsburgh SOM, Pittsburgh, PA; Jingsi Zhao, Univ of Pittsburgh, Pittsburgh, PA; Ying Tang, Univ of Pittsburgh SOM, Pittsburgh, PA; Yi Yin Tai, Univ of Pittsburgh, Pittsburgh, PA; Dror Perk, Univ of Pittsburgh Sch of Med, Pittsburgh, PA; Vinny Negi, Univ of Pittsburgh, Pittsburgh, PA; Yen Chun Lai, Indiana Univ, Indianapolis, IN; Qiujun Yu, Univ of Iowa Hosp, Iowa City, IA; Adam Handen, Univ of Pittsburgh Sch of Med, Pittsburgh, PA; Gil Speyer, Arizona State Univ, Tempe, AZ; Seungchan Kim, Prairie View A&M Univ, Prairie View, TX; Sruti Shiva, Univ of Pittsburgh Sch of Med, Pittsburgh, PA; Taijyu Satoh, Pittsburgh Univ, Pittsburgh, PA; Yassmin Al Aaraj, Univ of Pittsburgh Sch of Med, Pittsburgh, PA; John C Sembrat, UPMC, Pittsburgh, PA; Mauricio Rojas, Univ of Pittsburgh Sch of Med, Pittsburgh, PA; Aditi Gurkar, Univ of Pittsburgh SOM, Pittsburgh, PA; Karen Norris, Univ of Georgia, Athens, GA; Marlene Rabinovitch, Stanford Univ Sch Med, Stanford, CA; Mingxia Gu, Stanford Sch of Med, Stanford, CA; Thomas Bertero, IRCAN, CNRS UMR7284, Nice, France; Stephen Y Chan, Univ of Pittsburgh, Pittsburgh, PA

1:00 PM

In vivo CRISPR Screening of GPCRome Identifies the Essential Role of CXCR4 in Endothelial Regeneration and Resolution of Inflammation

**Youyang Zhao** , Northwestern U-Lurie Children's H, Chicago, IL; Yujie Liu, Xianming Zhang, Northwestern Univ, Chicago, IL

1:10 PM

**Inflammation Triggers the Onset of Hereditary Pulmonary Arterial Hypertension in Kcnk3** -/- **Animals**

**Anandharajan Rathinasabapathy** , Eric Austin, Harikrishna Tanjore, Ling Yan, Gladson Muthian, Christy Moore, Sheila Shay, Tom Blackwell, Santhi Gladson, Taylor Sherrill, Rizwan Hamid, Susan Majka, James West, Vanderbilt Univ Medical Ctr, Nashville, TN

1:20 PM

Serca2a Gene Therapy Inhibits Pulmonary Fibrosis By Blocking The Stat3/foxm1 Pathway And Promoting The Snon/ski Axis

**Malik Bisserier** , Icahn Sch of Med at Mount Sinai, New York, NY

# Abstract Rapid Fire Oral

## EP.RFO39 - Fitness, Physical Activity and CVD Risk

#### Science and Technology Hall A, Booth 605, Level 2

### Monday, November 18, 2019, 12:40 PM - 1:30 PM

12:40 PM

Moderator

Satyam Sarma, Dallas, TX

12:40 PM

Renin-angiotensin System Inhibition, Cardiorespiratory Fitness On Mortality Risk In High Risk Patients

**Peter Kokkinos** , Charles Faselis, Pamela Karasik, Veterans Affairs Medical Ctr, Washington, DC; Labros Sidossis, Rutgers Univ, NEW BRUNSWICK, NJ; Andreas Pittaras, Michael Doumas, Hans Moore, Vasilios Papademetriou, Veterans Affairs Medical Ctr, Washington, DC; Mei Sui, Univ of South Carolina, COLUMBIA, SC; Jonathan Myers, Palo Alto Health Care Systems, PALO ALTO, CA

12:45 PM

Q & A

12:50 PM

Data From Wearable Devices Informs Ideal Cardiovascular Health: An Analysis From the American Heart Association's My Research Legacy Study

**Jane A Leopold** , Brigham Womens Hosp, Boston, MA; Elliott M. Antman, Brigham and Women's Hosp, Boston, MA

12:55 PM

Q & A

1:00 PM

Exercise Capacity is Inversely Related to Incident Heart Failure Among Men and Women With Coronary Heart Disease: Data From the Henry Ford Exercise Testing (FIT) Project

**Clinton A Brawner** , Henry Ford Hosp, Detroit, MI; Jonathan K Ehrman, Preventive Cardiology, Detroit, MI; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; Waqas Qureshi, Univ of Massachusetts, Shrewsbury, MA; Sarah A Gorgis, Steven J Keteyian, Henry Ford Hosp, Detroit, MI; Mouaz H Al-Mallah, Houston Methodist Hosp, Pearland, TX

1:05 PM

Q & A

1:10 PM

Performance of the Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Events Across Different Leisure Time Physical Activity Levels: The Cardiovascular Lifetime Risk Pooling Project

**Ambarish Pandey** , Univ of Texas Southwestern Medical Ctr, Dallas, TX; Amanda Paluch, Hongyan Ning, Northwestern Univ Sch of Med, Chicago, IL; Anurag Mehta, Emory Univ Sch of Med, Atlanta, GA; Mercedes R Carnethon, Norrina B Allen, Northwestern Univ, Chicago, IL; Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD; Jarett D Berry, UT Southwestern Medical Sch, Dallas, TX; Donald M Lloyd-jones, John T Wilkins, Northwestern Univ, Chicago, IL

1:15 PM

Q & A

1:20 PM

High Physical Activity May Mitigate Metabolic Risks Associated With Poor Diet Quality in Older Adults: The Framingham Heart Study

**Joowon Lee** , Maura E Walker, Ramachandran S Vasan, Boston Univ, Boston, MA; Vanessa Xanthakis, BU Sch of Med, Boston, MA

1:25 PM

Q & A

# Abstract Rapid Fire Oral

## HF.RFO36 - Rapid Whirlwind of Outcomes in Heart Failure and Cardiomyopathy

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 12:40 PM - 1:30 PM

12:40 PM

Moderator

Prateeti Khazanie, Denver, CO

12:40 PM

Increasing Mitral Regurgitation Severity is Accompanied by Higher Prevalence Of Atrial Fibrillation

**Zachary D. Brown** , Univ of North Carolina, Chapel Hill, NC; Michael Hendrickson, UNC Sch of Med, Chapel Hill, NC; Sameer Arora, Patricia Chang, Univ of North Carolina, Chapel Hill, NC; Arman Qamar, Brigham and Women's Hosp, Boston, MA; Elsayed Z Soliman, Wake Forest Sch of Med, Winston Salem, NC; Alvaro Alonso, Emory Univ, Atlanta, GA; Wayne D Rosamond, Univ NC Sch of Public Health, Chapel Hill, NC; John Paul Vavalle, Univ of North Carolina, Chapel Hill, NC

12:45 PM

Q & A

12:50 PM

Evaluating the Burden of Comorbidity on the Effect of Remote Noninvasive Tele-monitoring and Nurse Coaching for Patients With Heart Failure: A Secondary Analysis of the Beat-hf Trial

**Asher Kimchi** , Harriet U Aronow, Yu Ming Ni, Cedars-Sinai, Los Angeles, CA; Michael K Ong, UCLA, Los Angeles, CA; James Mirocha, Jeanne T Black, Cedars-Sinai, Los Angeles, CA; Andrew David Auerbach, UCSF, San Francisco, CA; Theodore G Ganiats, Univ of Miami, Miami, FL; Sheldon Greenfield, UCI, Irvine, CA; Patrick S Romano, UC Davis Health System, Sacramento, CA; Ilan Kedan, Cedars-Sinai, Los Angeles, CA

1:00 PM

Machine Learning-based Prediction of Cardiovascular Death in Patients With Hypertrophic Cardiomyopathy

**Stephanie M Kochav** , New York Presbyterian - Columbia Univ Medical Ctr, New York, NY; Yoshihiko Raita, Michael A Fifer, Massachusetts General Hosp, Boston, MA; Hiroo Takayama, New York Presbyterian - Columbia Univ Medical Ctr, New York, NY; Jonathan Ginns, New York Presbyterian - Weill Cornell Med, New York, NY; Mathew S Maurer, Muredach P Reilly, New York Presbyterian - Columbia Univ Medical Ctr, New York, NY; Kohei Hasegawa, Massachusetts General Hosp, Boston, MA; Yuichi J. Shimada, New York Presbyterian - Columbia Univ Medical Ctr, New York, NY

1:10 PM

Sickle Cell Disease is a Prognostic Indicator of Increased In-hospital Mortality in Heart Failure Admissions: Results of a National Inpatient Sample Database Study

**Maryam Gbadamosi-Akindele** , Dinesh Reddy Apala, Janani Baskaran, Sara Albagoush, Aravdeep Jhand, Daniel Ermann, Sarah Aurit, Hussain Rangoonwala, Margaret Butler, Peter Silberstein, Creighton Univ, Omaha, NE

1:20 PM

Human Immunodeficiency Virus Infection and Risks of Death and Heart Failure Hospitalization in Adults With Incident Heart Failure

**Harshith Reddy Avula** , Andrew Patrick Ambrosy, Kaiser Permanente San Francisco Medical Ctr, San Francisco, CA; Michael J Silverberg, KPNC Div of Res, Oakland, CA; Kristi Reynolds, Kaiser Permanente, Pasadena, CA; William J Towner, Rulin C Hechter, Kaiser Permanente Southern California, Pasadena, CA; Michael Horberg, Kaiser Permanente Mid-Atlantic Medical Group, Rockville, MD; Suma Vupputuri, Kaiser Permanente MidAtlanticStates, Rockville, MD; Thomas Kiichi Leong, Kaiser Permanente, Oakland, CA; Wendy A Leyden, Kaiser Permanente Northern California, Oakland, CA; Teresa Nina Harrison, Kaiser Permanente Southern CA, Pasadena, CA; Keane K Lee, Kaiser Permanente Santa Clara Homestead Medical Ctr, Santa Clara, CA; Sue Hee Sung, Kaiser Permanente, Oakland, CA; Alan S Go, Kaiser Permanente Northern CA, Oakland, CA

# Moderated Digital Posters

## CE.MDP65 - Always Being Right: The RV and Pulmonary Hypertension

#### Moderated Posters 6, Science and Technology Hall

### Monday, November 18, 2019, 12:40 PM - 1:30 PM

12:40 PM

Moderator

Michael A Portman, Seattle, WA

12:40 PM

**Development of Molecular Targeted Therapy Against Right Ventricular Failure: Evaluation by Transcriptome and in vivo** **Analysis**

**Shogo Ito** , Shinsuke Yuasa, Jin Komuro, Toshiomi Katsuki, Mai Kimura, Dai Kusumoto, Hisayuki Hashimoto, Keio Univ, Tokyo, Japan; Yoshihiro Fukumoto, Kurume Univ, Cardiovascular M, Kurume, Japan; Keiichi Fukuda, Keio Univ, Tokyo, Japan

12:45 PM

Q & A

12:50 PM

Mineralocorticoid-Receptor Antagonists Regulate Mitochondrial Dynamics and Local Aldosterone Production Attenuating Right Ventricular Remodeling in Pulmonary Arterial Hypertension

**Tetsuya Hayashi** , Osaka Univ Pharmaceutical Sciences, Takatsuki, Japan; Ryuji Kato, Osaka Univ of Pharmaceutical, Takatsuki, Japan; Hideki Imano, Yoshio Ijiri, Osaka Univ Pharmaceutical Sciences, Takatsuki, Japan; Atsuo Nomura, Michio Asahi, Hong Wu, Takashi Nakano, Osaka Medical Coll, Takatsuki, Japan; Takehiro Yamaguchi, Yasukatsu Izumi, Minoru Yoshiyama, Osaka City Univ Graduate Sch of Med, Osaka, Japan; Keiko Ohta-Ogo, Hatsue Ishibashi-Ueda, Natl Cerebral and Cardiovasculat Ctr, Suita, Japan

12:55 PM

Q & A

1:00 PM

**Whole Genome Sequencing and Heterologous Expression Studies Identify a Gain-of-Function Variant in** Pnn **-encoded Pinin as a Potential Cause of a Novel Sudden Cardiac Death-Predisposing Familial Right Ventricular Electropathy**

**Wei Zhou** , Whitney Barham, David J Tester, John R Giudicessi, Christopher J McLeod, Michael J Ackerman, Mayo Clinic, Rochester, MN

1:05 PM

Q & A

1:10 PM

Identification of ADORA1- PDE10A Complex Formation and Its Bidirectional Regulation of Intracellular Cyclic AMP Levels as a Novel Therapeutic Target for Treating Pulmonary Hypertension

**Chanil Valasarajan** , Max Planck Inst, Bad Nauheim, Germany; Julio Castro-Palomino Laria, Palobiofarma, Barcelona, Spain; Nahomi Castro-Palomino Laria, Palobiofarma, Barcelona, Germany; Astrid Wietelmann, Max Planck Inst, Bad Nauheim, Germany; Friedrich Grimminger, Universities of Giessen and Marburg Lung Ctr (UGMLC), member of the DZL, Giessen, Germany; Werner Seeger, Max Planck Inst for Heart and Lung Res, Bad Nauheim, Germany; Soni Pullamsetti, Max Planck Inst, Bad Nauheim, Germany

1:15 PM

Q & A

1:20 PM

Loss of Endothelial BMPR1A Results in Pulmonary Hypertension Through Endothelial to Mesenchymal Transition

**Heon-Woo Lee** , Takaomi Adachi, Saejeong Park, Yale Univ, New Haven, CT; Boryeong Pak, Gwangju Inst of Science and Technology, Gwangju, Korea, Republic of; Piotr Kowalski, MIT, Cambridge, MA; Woosoung Choi, Gwangju Inst of Science and Technology, Gwangju, Korea, Republic of; Katharine Clapham, Yale New Haven Hosp, New Haven, CT; Ahram Lee, Gwangju Inst of Science and Technology, New Haven, CT; Daniel Anderson, MIT, Cambridge, MA; Michael Simons, Yale Univ Sch of Med, New Haven, CT; Suk-won Jin, Gwangju Inst of Science and Technology, Gwangju, Korea, Republic of; Hyung J Chun, Yale Univ Sch Med, New Haven, CT

1:25 PM

Q & A

# Moderated Digital Posters

## DD.MDP59 - Cardioprotection

#### Moderated Posters 4, Science and Technology Hall

### Monday, November 18, 2019, 12:40 PM - 1:30 PM

12:40 PM

A Short Connexin43 Carboxyl Terminal-Based Peptide Permeates Hemichannels and Provides Post-Infarction Cardioprotection in vivo

Stefano Toldo, Virginia Commonwealth Univ, Richmond, VA; Jingbo Jiang, Guangdong Cardiovascular Inst, Guangzhou, China; Antonio Abbate, Virginia Commonwealth Univ, Richmond, VA; Jane L Jourdan, **Robert G Gourdie** , Fralin Biomedical Res Inst, Virginia Tech, Roanoke, VA

12:45 PM

Q & A

12:50 PM

All Caspase-1-dependent Myocardial Infarction Occurs in the First 10 Minutes of Reperfusion

**Michael V Cohen** , Xi-Ming Yang, James M Downey, Univ of South Alabama, Mobile, AL

12:55 PM

Q & A

1:00 PM

Bone Marrow-Derived Adiponectin Protected Cardiomyocytes and Fibroblasts in Retnla Deficiency

**Yong Sook Grace Kim** , Dong Im Cho, Chonnam Univ Hosp, Gwangju, Korea, Republic of; Hyang Hee Cho, Chonnam Natl Univ Hosp, Gwangju; Youngkeun Ahn, Chonnam Nat Univ Hosp, Gwangju

1:05 PM

Q & A

1:10 PM

Electrospun Nanofiber-Based Scaffolds Containing Mitochondrial-Targeted Antioxidants Reduce Mitochondrial Oxidative Stress in Human Coronary Artery Endothelial Cells

**Yasaman Hamedani** , Univ of Massachusetts Dartmouth, North Dartmouth, MA; Rayane Teixeira, Brown Univ Warren Alpert Med, Providence, RI; Peter Wipf, Univ of Pittsburgh, Pittsburgh, PA; Sankha Bhowmick, Univ of Massachusetts Dartmouth, North Dartmouth, MA; Ruhul Abid, Brown Univ Warren Alpert Med, Providence, RI

1:15 PM

Q & A

1:20 PM

Global, but Not Cardiac Specific, Knockout of ROMK Potassium Channels Worsens Cardiac Ischemia Reperfusion Injury

**Kyriakos Papanicolaou** , Johns Hopkins Univ SOM, Baltimore, MD; Deepthi Ashok, Johns Hopkins Univ, Baltimore, MD; Ting Liu, Johns Hopkins Univ SOM, Baltimore, MD; Tyler Bauer, Natl Insts of Health, Bethesda, MD; Zhen Li, LSU Health Sciences Ctr - NO, New Orleans, LA; Eduardo Da Costa, Charles Crepy, Sara Nathan, Johns Hopkins Univ SOM, Baltimore, MD; David J Lefer, LSU Health Sciences Ctr NO, New Orleans, LA; Elizabeth Murphy, NIH, Bethesda, MD; Nazareno Paolocci, Johns Hopkins Medical Insts, Baltimore, MD; D Brian Foster, Johns Hopkins Sch of Med, Baltimore, MD; Brian O'Rourke, Johns Hopkins Univ, Baltimore, MD

1:25 PM

Q & A

# Moderated Digital Posters

## HF.MDP50 - Hemodynamics, Myocardial Structure/Function Still Matter in Heart Failure

#### Moderated Posters 1, Science and Technology Hall

### Monday, November 18, 2019, 12:40 PM - 1:30 PM

12:40 PM

First Phase Ejection Fraction is Impaired in Patients With Heart Failure and Preserved Ejection Fraction and Predicts Adverse Clinical Outcomes

**Haotian Gu** , Jessica Webb, King's Coll London, London, United Kingdom; Reza Razavi, Kings Coll London, London; Ajay Shah, Kings Coll London, London, United Kingdom; Gerry Carr-White, Guy's and St Thomas' NHS Fndn Trust, London, United Kingdom; Phil Chowienczyk, St Thomas' Hosp, London

12:45 PM

Q & A

12:50 PM

Significance and Prognostic Impact of V Wave on Pulmonary Artery Pressure in Patients With Heart Failure: Beyond the Wedge Pressure

**Hiroyuki Iwano** , Hokkaido Univ, Sapporo, Japan; Shinobu Yokoyama, Hokkaido Univ Hosp, Sapporo, Japan; Kiwamu Kamiya, Toshiyuki Nagai, Shingo Tsujinaga, Miwa Sarashina, Suguru Ishizaka, Yasuyuki Chiba, Hokkaido Univ, Sapporo, Japan; Masahiro Nakabachi, Hokkaido Univ Hosp, Sapporo, Japan; hisao nishino, Hokkaido Univ Hosp, sapporo, Japan; Michito Murayama, Hokkaido Univ Hosp, Sapporo, Japan; Kazunori Okada, Sanae Kaga, Toshihisa Anzai, Hokkaido Univ, Sapporo, Japan

12:55 PM

Q & A

1:00 PM

Left Ventricular Global Longitudinal Strain Predicting Clinical Outcomes in Heart Failure Patients With Mild-to-Severely Reduced Ejection Fraction

**Diego Medvedofsky** , MedStar Washington Hosp Ctr, Washington, DC; Genevieve Arany-Lao-Kan, Scott McNitt, Univ of Rochester Medical Ctr, Rochester, NY; Roberto M Lang, Univ Chicago Medical Ctr, Chicago, IL; Scott D Solomon, BRIGHAM AND WOMENS HOSPITAL, Boston, MA; Ilan Goldenberg, Univ of Rochester, Rochester, NY; Valentina Kutyifa, UNIVERSITY OF ROCHESTER, Rochester, NY

1:05 PM

Q & A

1:10 PM

Nighttime Hemodynamics Predicts Post-Discharge Outcomes in Patients Hospitalized for Acute Heart Failure

**Hao-Chih Chang** , Taipei Veterans General Hosp, Taipei, Taiwan; Shih-Hsien Sung, Chen-Huan Chen, Taipei Veterans General Hosp, Natl Yang Ming Univ, Taipei, Taiwan

1:15 PM

Q & A

1:20 PM

Improved Right Ventricular Hemodynamic Effects of Biventricular versus Alternative Pacing Strategies in LVAD Patients

**Brett Tomashitis** , Medical Univ of SC, Charleston, SC; Catalin F Baicu, Ryan J Tedford, Medical Univ South Carolina, Charleston, SC; Greg Jackson, Jeffrey Winterfield, Medical Univ of SC, Charleston, SC; Michael R Zile, Medical Univ of South Carolina, Charleston, SC; Michael R Gold, Medical Univ South Carolina, Charleston, SC; Brian A Houston, Medical Univ of SC, Charleston, SC

1:25 PM

Q & A

# Moderated Digital Posters

## IM.MDP56 - How Does Cardiac CT Perform for Determination of Prognosis and Outcomes?

#### Moderated Posters 3, Science and Technology Hall

### Monday, November 18, 2019, 12:40 PM - 1:30 PM

12:40 PM

Association of Automated Deep Learning Coronary Artery Calcium Score on ECG-Gated and Non-ECG Gated CT With Future Cardiac Events: Insights From ROMICAT-II and NLST

**Michael T Lu** , Massachusetts General Hosp, Boston, MA; Roman Zeleznik, Dana Farber Cancer Inst and Brigham and Women's Hosp, Boston, MA; Borek Foldyna, Massachusetts General Hosp, Boston, MA; Parastou Eslami, MGH, Boston, MA; Alexander Ivanov, Massachusetts General Hosp, Boston, MA; Chintan Parmar, DFCI, Boston, MA; Jakob Weiss, Dana Farber Cancer Inst and Brigham and Women's Hosp, Boston, MA; Jana Taron, Raza Alvi, Dahlia Banerji, Mio UNO, Yasuka Kikuchi, Jan-Erik Scholtz, Massachusetts General Hosp, Boston, MA; Hugo Aerts, DFCI, Boston, MA; Udo Hoffmann, Massachusetts General Hosp, Boston, MA

12:45 PM

Q & A

12:50 PM

Differences in the Non-Invasive Evaluation for Coronary Artery Disease and Its Prognostic Implications by Patient Age: An Evaluation of the PROMISE Trial

**Angela Lowenstern** , Duke Univ, Durham, NC; Karen P Alexander, Duke Univ Medical Ctr, Durham, NC; Larry Hill, Duke Univ Sch of Med, Durham, NC; Brooke Alhanti, Duke Univ, Durham, NC; Patricia A Pellikka, Mayo Clinic Coll Med, Rochester, MN; Michael Nanna, Raj Mehta, Duke Univ Sch of Med, Durham, NC; Lawton S Cooper, NHLBI, Silver Spring, MD; Renee P. Bullock-Palmer, Deborah Heart and Lung Ctr, Browns Mills, NJ; Udo Hoffmann, Massachusetts General Hosp, Boston, MA; Pamela S Douglas, Duke Univ DUMC, Durham, NC

12:55 PM

Q & A

1:00 PM

Association of Statin Therapy With Long-term Cardiovascular Outcomes by Coronary Artery Calcium in Asymptomatic Patients: The Multi-ethnic Study of Atherosclerosis

**Zhen Zhou** , Menzies Inst for Medical Res, Univ of Tasmania, Hobart, TAS, Australia; Kwok Leung Ong, Sch of Medical Sciences, Univ of New South Wales, Sydney, NSW, Australia; Monique Breslin, Menzies Inst for Medical Res, Univ of Tasmania, Hobart, TAS, Australia; Matthew A Allison, Univ of California San Diego, La Jolla, CA; Andrea J Curtis, Sch of Public Health and Preventive Med, Monash Univ, Melbourne, VIC, Australia; Gregory L Burke, Wake Forest Sch of Med, Winston-Salem, NC; Mark R Nelson, Menzies Inst for Medical Res, Univ of Tasmania, Hobart, TAS, Australia

1:05 PM

Q & A

1:10 PM

Coronary Artery Calcium Score and Cardiovascular Events in Patients With Diabetes, Prediabetes, and No Diabetes: The Clarify Registry

**Nour Tashtish** , Univ Hosp Cleveland Ctr, Cleveland, OH; Sadeer Al-Kindi, Univ Hosp Case Medical Ctr, Cleveland, OH; Anuja Sarode, Jared Derieux, Univ Hosp Cleveland Ctr, Cleveland, OH; Robert Gilkeson, Univ Hosp Cleveland Medical Ctr, Cleveland, OH; Sanjay Rajagopalan, Case Medical Ctr, Cleveland, OH

1:15 PM

Q & A

1:20 PM

The Effect of Coronary Artery Calcifications on Hospital Outcomes in Patients With Acute Decompensated Heart Failure

Wafic Itani, Hiren Patel, **Evan Joye** , Anish Adhikari, Mikhail Torosoff, Albany Medical Ctr, Albany, NY

1:25 PM

Q & A

# Moderated Digital Posters

## SA.MDP53 - Late Breaking Science in Cardiothoracic Surgery and Anesthesia

#### Moderated Posters 2, Science and Technology Hall

### Monday, November 18, 2019, 12:40 PM - 1:30 PM

12:40 PM

Moderator

Jennifer S Lawton, Baltimore, MD

12:40 PM

Human Derived Anatomically Oriented Smooth Muscle Cell-Endothelial Progenitor Bi-Level Cell Sheet Augment Post-Infarction Ventricular Function

**Yasuhiro Shudo** , Akshara Thakore, Hye Sook Shin, Camille Hironaka, Anahita Eskandari, Haley Lucian, Justin Farry, Samantha C Roach, Amanda N Steele, Lyndsay Stapleton, Hanjay Wang, Michael J Paulsen, Yuko Tada, Gentaro Ikeda, Phillip C Yang, Masataka Nishiga, Ian Ying-Li Chen, Stanford Univ, Stanford, CA; Shigeru Miyagawa, Osaka Univ Sch of Med, Suita, Japan; Yoshiki Sawa, Osaka Univ Sch of Med, Osaka, Japan; Joseph Woo, Stanford Univ, Stanford, CA

12:45 PM

Q & A

12:50 PM

Cardioprotective Mechanisms of Mitochondrial-Targeted Antioxidant MitoSNO and Adenosine Triphosphate-Sensitive Potassium Channel Opener Diazoxide Are Distinct and Mutually Exclusive

**Thaniyyah Ahmad** , Jie Wang, Alejandro Suarez-Pierre, Jie Dong, Johns Hopkins Univ, Baltimore, MD; Michael P Murphy, MRC Mitochondrial Biology Unit, Cambridge, United Kingdom; Jennifer S Lawton, Johns Hopkins Univ, Baltimore, MD

12:55 PM

Q & A

1:00 PM

Effects of High Fat vs Normal Diet on Extracellular Vesicles-Induced Angiogenesis in a Swine Model of Chronic Myocardial Ischemia

**Ahmed M Aboulgheit** , Warren Alpert Sch of Med Brown Univ, Providence, RI; Zhiqi Zhang, Rhode Island Hosp, Providence, RI; Brittany A Potz, Laura Scrimgeour, Brown Univ, Providence, RI; Karla Braga, Melissa Pfeiffer, May Gao, Olivia Cummings, Warren Alpert Sch of Med, Providence, RI; Neel Sodha, Warren Alpert Sch of Med Brown Univ, Providence, RI; Ruhul Abid, Brown Univ Warren Alpert Med, Providence, RI; Frank W Sellke, Brown Medical Sch, Providence, RI

1:05 PM

Q & A

1:10 PM

Sex-Differential Mitochondrial Responses Following Acute Myocardial Ischemia/Reperfusion

**Meijing Wang** , Qing Yu, Kwynlyn Smith, Caroline Miller, Mark Turrentine, IU Sch Med, Indianapolis, IN

1:15 PM

Q & A

1:20 PM

Oxidative Stress in the Myocardium as a Novel Predictor of Long-Term Outcomes in Patients Undergoing Cardiac Surgery

**Christos P Kotanidis** , Alexios S Antonopoulos, Evangelos K Oikonomou, Ioannis Akoumianakis, Ileana Badi, Univ of Oxford, Oxford, United Kingdom; George Krasopoulos, Rana Sayeed, Mario Petrou, Vivek Srivastava, Shakil Farid, Oxford Univ Hosp NHS Fndn Trust, Oxford, United Kingdom; Nikolaos Galiatsatos, Hippokration General Hosp of Athens, Athens, Greece; Keith M Channon, Charalambos Antoniades, Univ of Oxford, Oxford, United Kingdom

1:25 PM

Q & A

# Moderated Digital Posters

## LF.MDP68 - Lipids and Lipoproteins: Metabolism and Therapies

#### Moderated Posters 7, Science and Technology Hall

### Monday, November 18, 2019, 12:40 PM - 1:30 PM

12:40 PM

Androgen Abuse is Associated With Reversible, HDL-dependent Suppression of Cholesterol Efflux Capacity

**Christopher Yu** , Concord Repatriation General Hosp, Sydney, Australia; Maaike Kockx, Nandini Shankara Narayana, Univ of Sydney, Sydney, Australia; Sasha Savkovic, Carolyn Fennel, Leo Turner, Veena Jayadev, Ann Conway, Leonard Kritharides, Concord Repatriation General Hosp, Sydney, Australia; David J Handelsman, Univ of Sydney, Sydney, Australia

12:45 PM

Q & A

12:50 PM

Relationship Between Nitric Oxide Bioavailability and Modified Low Density Lipoproteins and Their Impact on Vascular Outcome in African Americans With Type Ii Diabetes

**Ahmed Bakillah** , King Abdullah Intl Medical Res Ctr (KAIMRC)/King Saud Bin Abdulaziz Univ for Health Sciences (KSAU-HS), Ministry of Natl Guard Health Affairs, Al Ahsa, Saudi Arabia; Ajibola Monsur Adedayo, SUNY Downstate Medical Ctr, Brooklyn, NY; Ayobami Eluwole, Fasika Tedla, Arye Kremer, Mastrogiovanni Nicole, Muhammad Khan, Downstate Medical Ctr, Brooklyn, NY; Carl Rosenberg, SUNY Downstate Sch of Public Health, Brooklyn, NY; Dreizen Paul, Downstate Medical Ctr, Brooklyn, NY; John C LaRosa, State Univ of New York Health Science Ctr, New York, NY; Louis Salciccioli, Mohamed Boutjdir, Mary Ann Banerji, Clinton D Brown, Moro Salifu, Jason Lazar, Downstate Medical Ctr, Brooklyn, NY

12:55 PM

Q & A

1:00 PM

Meta Analysis of Efficacy and Safety of Bempedoic Acid in Lowering Low Density Lipoprotein Cholesterol

**Muhammad Usman Khan** , West Virginia Univ, HSC, Morgantown, WV; Safi Ullah Khan, West Virginia Univ, Morgantown, WV; Muhammad khan, WV Med, Section Of Hosp Me, Morgantown, WV; Ahmad Naeem Lone, West Virginia Univ, Sch of Med, Morgantown, WV; Shahul Valavoor, West Virginia Univ, Morgantown, WV; Charumathi Raghu, Washington Hosp Health Care System, Fremont, CA; Adeel Arshad, Unity Hosp/Rochester Regional Health, Rochester, NY; Swapna Talluri, Guthrie Clinic / Robert Packer Hosp, Sayre, PA; Mohamad Adnan Alkhouli, West Virginia Univ, Morgantown, WV

1:05 PM

Q & A

1:10 PM

Marked Elevation of Mature PCSK9 Levels and Inversely Decrease of Furin-cleaved PCSK9 Levels After Administration of PCSK9 Inhibitor in Patients With Acute Myocardial Infarction

**Akihiro Nakamura** , Yuta Kagaya, Masanori Kanazawa, Masateru Kondo, Kenjiro Sato, Hideaki Endo, Eiji Nozaki, Iwate Prefectural Central Hosp, Morioka, Japan

1:15 PM

Q & A

1:20 PM

Many Statin Treated Persons With Borderline Triglyceride Levels are at Risk of ASCVD

**Nathan D Wong** , Wenjun Fan, Univ of California Irvine, Irvine, CA; Sephy Philip, Amarin, Basking Ridge, NJ; Peter P. Toth, CGH Medical Ctr, Sterling, IL; Craig Granowitz, Amarin Pharma Inc., Bedminster, NJ

1:25 PM

Q & A

# Moderated Digital Posters

## AT.MDP62 - Microvascular Dysfunction - an Emerging Culprit Underlying Cardiovascular Disease

#### Moderated Posters 5, Science and Technology Hall

### Monday, November 18, 2019, 12:40 PM - 1:30 PM

12:40 PM

Moderator

John M Canty Jr., Buffalo, NY

12:40 PM

Decreases in Coronary Vasodilator Reserve Increases the Risk for Heart Failure

**Vahagn A Ohanyan** , Liya Yin, Lindsay Shockling, Molly Enrick, Christopher Kolz, Thomas Pucci, Taylor Elder, William M Chilian, Northeast Ohio Medical Univ, Rootstown, OH

12:45 PM

Q & A

12:50 PM

Impaired Peripheral Microvascular Function and Risk of Major Adverse Cardiovascular Events in Patients With Coronary Artery Disease

**An Young** , Samaah Sullivan, Bruno B Lima, Chang Liu, Muhammad Hammadah, Yi-An Ko, Amit J Shah, Jeong Hwan Kim, Emory Univ, Atlanta, GA; Kasra Moazzami, Emory Univ, Brookhaven, GA; Mhmtjamil Alkhalaf, J Douglas Bremner, Emory Univ, Atlanta, GA; Paolo Raggi, Mazankowski Alberta Heart Inst, Edmonton, AB, Canada; Arshed A Quyyumi, Viola Vaccarino, Emory Univ, Atlanta, GA

12:55 PM

Q & A

1:00 PM

E-cigarette Use Leads to Impaired Coronary Endothelial Function in Young Adults

**Mohamad Rashid** , Katherine Davoren, Norma B. Moy, Fida Nafeh, Cedars-Sinai Medical Ctr, Los Angeles, CA; Robert Elashoff, UCLA Sch of Public Health, Los Angeles, CA; Chulkyu Kim, Elizabeth Kim, Susan Cheng, Florian Rader, Cedars-Sinai Medical Ctr, Los Angeles, CA

1:05 PM

Q & A

1:10 PM

Impact of Enterectomy on Coronary Microcirculation in Patients With Inflammatory Bowel Disease

**Kentaro Kakuta** , Japan Community Health care Organization Yokkaichi Hazu Medical Ctr, Yokkaichi, Japan; Kaoru Dohi, Mie Univ Graduate Sch of Med, Tsu, Japan; Takayuki Yamamoto, Japan Community Health Care Organization Yokkaichi Hazu Medical Ctr, Yokkaichi, Japan; Naoki Fujimoto, Mie Univ Graduate Sch of Med, Tsu, Japan; Takahiro Shimoyama, Satoru Umegae, Japan Community Health Care Organization Yokkaichi Hazu Medical Ctr, Yokkaichi, Japan; Yasuhiro Saito, Suzuka Kaisei Hosp, Suzuka, Japan; Masaaki Ito, Mie Univ Graduate Sch of Med, Tsu, Japan

1:15 PM

Q & A

1:20 PM

The Mediator of Coronary Dilation Switch in Metabolic Syndrome

**Zhiyuan Wang** , Cody Juguilon, Molly Enrick, Dept of Integrative Medical Sciences, Northeast Ohio Medical Univ, Rootstown, OH; Anurag Jamaiyar, Northeast Ohio Medical Univ, Rootstown, OH; Tao Wang, Chris Kolz, Dept of Integrative Medical Sciences, Northeast Ohio Medical Univ, Rootstown, OH; William M Chilian, Liya Yin, Northeast Ohio Medical Univ, Rootstown, OH

1:25 PM

Q & A

# Moderated Digital Posters

## PR.MDP71 - Stress Testing Exercise and Pharmacologic

#### Moderated Posters 8, Science and Technology Hall

### Monday, November 18, 2019, 12:40 PM - 1:30 PM

12:45 PM

Q & A

12:50 PM

Association Between Abnormal Stress Test Findings and Cancer Mortality by Smoking Status and Cancer Site

**Yazan Assaf** , Maria Irene Barillas-Lara, Sonia Fortin-Gamero, Mayo Clinic, Rochester, MN; Nasir Hussain, Saint Joseph Hosp, Chicago, IL; Amanda Bonikowske, Mayo Clinic, Rochester, MN; Nora SYDO, Aritmia Fndn, Budapest, Hungary; Thomas G Allison, Mayo Clinic, Rochester, MN

12:55 PM

Q & A

1:00 PM

Arm Exercise ECG is Equivalent to Regadenoson Stress for Detection of Obstructive Coronary Artery Disease

**Anandita Agarwala** , Washington Univ Sch of Med, Saint Louis, MO; Clarence Balke, St. Louis Veterans Admin Healthcare System, Saint Louis, MO; Divya Kapoor, St. Louis Veterans Admin Heathcare System, St louis, MO; Jiafu Ou, St. Louis Veterans Admin Healthcare System, St. Louis, MO; Hong Xian, St. Louis Univ, Saint Louis, MO; Medhat Osman, St. Louis Univ Sch of Med, Saint Louis, MO; Jeffrey Chenoweth, St. Louis Veterans Admin Healthcare System, Saint Louis, MO; Wade H Martin III, St. Louis VAMC, Saint Louis, MO

1:05 PM

Q & A

1:10 PM

Arm Versus Treadmill Exercise for Detection of Cardiac Ischemia

**Anandita Agarwala** , Washington Univ Sch of Med, Saint Louis, MO; Divya Kapoor, St. Louis VA Healthcare System, St. Louis, MO; Clarence Balke, St. Louis VA Healthcare System, Saint Louis, MO; Jiafu Ou, St. Louis VA Healthcare System, St. Louis, MO; Hong Xian, St. Louis Univ Sch of Med, Saint Louis, MO; Wade Martin, St. Louis VA Healthcare System, Saint Louis, MO

1:15 PM

Q & A

1:20 PM

Early Life Competitive Sport Participation May Lead to Fewer Long-Term Cardiovascular Risk Factors in a Population of Ultramarathon Runners

Ankit B Shah, MedStar Heart & Vascular Inst, Baltimore, MD; **Umar Khan** , Georgetown Univ Sch of Med, Washington, DC; Rebecca Torguson, MedStar Washington Hosp Ctr, Washington, DC; Kezia Alexander, MedStar Health Res Inst, Hyattsville, MD; Cheng Zhang, Paige E Craig, MedStar Washington Hosp Ctr, Washington, DC; Casey Fisher, MedStart Health, Baltimore, MD; Matthew Sedgley, Medstar Health, Baltimore, MD; Aaron L Baggish, Massachusetts General Hosp, Boston, MA; Andrew E Lincoln, MedStar Health Res Inst, Hyattsville, MD

1:25 PM

Q & A

# Abstract Oral Session

## HT.AOS.HTP1 - HealthTech Pavilion Abstract Session: Machine Learning Applied to Clinical Care

#### Health Innovation Pavilion, Heart Hub, Science and Technology Hall, Level 2

### Monday, November 18, 2019, 1:00 PM - 1:48 PM

1:00 PM

Moderator

Ann Marie Navar, Durham, NC

1:00 PM

Moderator

Hamid Ghanbari, Ann Arbor, MI

1:00 PM

Direct Estimation of Diastolic Function From 2-Dimensional Echocardiography Videos Using Convolutional Neural Networks

**Shinichi Goto** , Calum A Macrae, Rahul C Deo, One Brave Idea/Brigham and Women's Hosp, Boston, MA

1:05 PM

Q&A

1:08 PM

Network-Based Analysis to Risk Stratify Patients With Cancer Therapy-Related Cardiac Dysfunction

**Feixiong Cheng** , Yuan Hou, Yadi Zhou, Muzna Hussain, Wai Hong Wilson Tang, Cleveland Clinic, Cleveland, OH; Chris Watson, Queens Univ, Belfast, United Kingdom; Thomas Budd, Cleveland Clinic, Cleveland, OH; Chirag Shah, Chirag Shah, Cleveland, OH; Rohit Moudgil, Zoran B Popovic, Brian P. Griffin, Mohamed H Kanj, Patrick Collier, Cleveland Clinic, Cleveland, OH

1:13 PM

Q&A

1:16 PM

Machine Learning for Prediction of Cardiovascular Outcomes in Symptomatic Outpatients With Suspected Coronary Artery Disease Having Coronary CT Angiography: A Secondary Analysis of the Promise Trial

**Lili Zhang** , Masschusetts General Hosp, Boston, MA; Thomas Mayrhofer, Stralsund Univ of Applied Sci, Stralsund; Borek Foldyna, Massachusetts General Hosp, Boston, MA; Stefan B Puchner, Masschusetts General Hosp, Boston, MA; Hamed Emami, Univ of Michigan, Northville, MI; Daniel Bittner, Univ Hosp Erlangen, Friedrich-Alexander Univ Erlangen-Nürnberg (FAU), Erlangen; Nandini Meyersohn, Massachusetts General Hosp, Boston, MA; Stefan Puchner, Masschusetts General Hosp, Boston, MA; Maros Ferencik, OHSU, Portland, OR; Pamela S Douglas, Duke Univ DUMC, Durham, NC; Udo Hoffmann, Michael T Lu, Massachusetts General Hosp, Boston, MA

1:21 PM

Q&A

1:24 PM

The Impact of Time Horizon on Classification Accuracy for Application of Machine Learning to Prediction of Incident Coronary Heart Disease in the Jackson Heart Study

**Steven Simon** , Leslie Lange, Michael A Rosenberg, Univ of Colorado, Aurora, CO

1:29 PM

Q&A

1:32 PM

Using Predictive Machine Learning Modeling for the Nursing Triage of Acute Chest Pain at the Emergency Department

**Stephanie O Frisch** , Hongjin Li, Univ of Pittsburgh, Pittsburgh, PA; Ziad Faramand, Univ of Pittsburgh Medical Ce, Pittsburgh, PA; Christian Martin-Gill, Univ of Pittsburgh, Pittsburgh, PA; Clifton W Callaway, Univ Pittsburgh, Pittsburgh, PA; Ervin Sejdic, Salah S Al-Zaiti, Univ of Pittsburgh, Pittsburgh, PA

1:37 PM

Q&A

1:40 PM

Assessment of Cardiac Rejection Grade via Machine Learning Derived Features From Digital Biopsy Images

**Sara ArabYarmohammadi** , Andrew Janowczyk, Case Western Reserve Univ, Cleveland, OH; Eliot G Peyster, Hosp of the Univ of Pennsylvania, Philadelphia, PA; Sepideh Azarianpour, Case Western Reserve Univ, Cleveland, OH; Priti Lal, Univ of Pennsylvania Perelman Sch of Med, Philadelphia, PA; Michael D. Feldman, Univ of Pennsylvania Perelman, Philadelphia, PA; Kenneth Margulies, Univ of Pennsylvania, Philadelphia, PA; Anant Madabhushi, Case Western Reserve Univ, Cleveland, OH

1:45 PM

Q & A

# Expert Theater

## ET.29 - Janssen Pharmaceuticals, Inc

#### Heart Theater, Booth # 17

### Monday, November 18, 2019, 1:15 PM - 2:00 PM

This is not a CME/CE certified session

# Expert Theater

## ET.30 - Merck

#### Learning Studio 1, Booth # 5

### Monday, November 18, 2019, 1:15 PM - 2:00 PM

This is not a CME/CE certified session

# Expert Theater

## ET.31 - OPEN

#### Learning Studio 2, Booth # 7

### Monday, November 18, 2019, 1:15 PM - 2:00 PM

This is not a CME/CE certified session

# Abstract Poster Session

## HF.APS.47 - Additional Insights into Pharmacological Therapy of HF

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2322

Impact of a Resident Driven Multidisciplinary Multimodal Approach in Reducing Heart Failure Readmissions at a Community Based Teaching Hospital

**Mrinali Shetty** , Univ of Chicago (NorthShore), Evanston, IL; Yuvraj S Chowdhury, SUNY Downstate Medical Ctr, Brooklyn, NY

1:30 PM

Board # 2323

Angiotensin Receptor-neprilysin Inhibitor Therapy is Associated With Improved Echocardiographic Parameters in Chronic Heart Failure Patients With Reduced Ejection Fraction

**Gregor Poglajen** , Ajda Anžič Drofenik, Dominika Jurca, Gregor Zemljic, Andraz Cerar, Renata Okrajšek, UMC Ljubljana, Ljubljana, Slovenia; Miran Sebestjen, UKC Ljubljana, Ljubljana, Slovenia; Sabina Frljak, Bojan Vrtovec, UMC Ljubljana, Ljubljana, Slovenia

1:30 PM

Board # 2324

Clinical Implication of Very Low Dose of Sacubitril/valsartan for Patients With Heart Failure With Reduced Ejection Fraction; Beyond PARADIGM-HF and PIONEER-HF Trial

**Hyoeun Kim** , Severance Hosp, Seoul, Korea, Republic of; Jaewon Oh, Jaehyung Ha, Kyeong-Hyeon Chun, Chan Joo Lee, Sungha Park, Sang-Hak Lee, Seok-Min Kang, Severance Cardiovascular Hosp, Yonsei Univ Coll of Med, Seoul, Korea, Republic of

1:30 PM

Board # 2325

Additional Mineralocorticoid-receptor Antagonist Improves Cardiovascular Mortality in Heart Failure Patients With Insufficient Dose of Guideline-recommended Medication

**Takuro Abe** , Kentaro Jujo, Tokyo Women's Medical Univ Hosp, Tokyo, Japan; Noritoshi Fukushima, Tokyo Medical Univ, Tokyo, Japan; Yuichiro Minami, Motoko Kametani, Haruki Sekiguchi, Tokyo Women's Medical Univ Hosp, Tokyo, Japan; Katsumi Saito, Nishiarai Heart Ctr Hosp, Tokyo, Japan; Nobuhisa Hagiwara, Tokyo Women's Medical Univ Hosp, Tokyo, Japan

1:30 PM

Board # 2326

Benzodiazepine is Associated With Adverse Prognosis in Heart Failure Patients With Insomnia

**Yu Sato** , Akiomi Yoshihisa, Yu Hotsuki, Koichiro Watanabe, Yusuke Kimishima, Takatoyo Kiko, Yuki Kanno, Tetsuro Yokokawa, Satoshi Abe, Tomofumi Misaka, Takamasa Sato, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

1:30 PM

Board # 2327

Faster Recovery in Takotsubo With Prior Beta-blocker Use

**Bader Abu Ghalyoun** , Nirmal Guragai, Rana Garris, Dema Shamoon, St Joseph's Univ Medical Ctr, PATERSON, NJ; Anthony Chuang, Flinders Medical Ctr, Bedford Park, SA, Australia; fayez shamoon, St Joseph's Univ Medical Ctr, PATERSON, NJ

1:30 PM

Board # 2328

Direct Oral Anticoagulants versus Warfarin for Left Ventricular Thrombi: The RED VELVT Study

**Austin A Robinson** , Univ of Virginia, Charlottesville, VA; Cory R Trankle, Virginia Commonwealth Univ, Richmond, VA; Grayson Eubanks, Univ of North Carolina, Chapel Hill, NC; Christopher Schumann, Paul Thomspon, Univ of Virginia, Charlottesville, VA; Ryan Wallace, Virginia Commonwealth Univ, Richmond, VA; Shouri Gottiparthi, Univ of North Carolina, Chapel Hill, NC; Benjamin Ruth, Univ of Virginia, Hershey, PA; Christopher M Kramer, Univ of Virginia Health Syste, Charlottesvle, VA; Michael Salerno, Univ of Virginia, Charlottesville, VA; Kenneth C Bilchick, Univ of Virginia HS, Charlottesvle, VA; Cody S Deen, UNC, Chapel Hill, NC; Michael C Kontos, Virginia Commonwealth Univ, Glen Allen, VA; John M Dent, Univ of Virginia, Charlottesvle, VA

1:30 PM

Board # 2329

Comparison of Angiotensin-converting Enzyme Inhibitors and Angiotensin II Receptor Blockers for Prognosis of Heart Failure in the Real World

**Kensaku Higashi** , Natl Hosp Organization Kagoshima Medical Ctr, Kagoshima, Japan

1:30 PM

Board # 2330

Beta Blockers After HFrEF Hospitalization Decrease 1-Year Mortality Across the Age Spectrum Beta Blockers After HFrEF Hospitalization Decrease 1-Year Mortality Across the Age Spectrum

**Lauren Gilstrap** , Dartmouth Hitchcock Medical Ctr, Lebanon, NH; Andrea Austin, The Dartmouth Inst, Lebanon, NH; Barbara Gladders, Dartmouth Hitchcock Medical Ctr, Lebanon, NH; James O'Malley, Amber Barnato, Anna N.A. Tosteson, Jonathan Skinner, The Dartmouth Inst, Lebanon, NH

1:30 PM

Poster Professor

Javed Butler, Jackson, MS

# Abstract Poster Session

## EA.APS.33 - Arrhythmias in Heart Failure and Systemic Disease

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2109

Heart Failure With Preserved Ejection Fraction is a Highly Arrhythmogenic Disease

**Alejandra Gutierrez** , Jerry Ash, Tamas Alexy, Baris Akdemir, Rebecca Cogswell, Univ of Minnesota, Minneapolis, MN; Selcuk Adabag, Minneapolis VA Medical Ctr, Minneapolis, MN

1:30 PM

Board # 2110

Ventricular Tachycardia is a Common Arrhythmia Among Patients With Heart Failure With Preserved Ejection Fraction

**Jerry Ash** , Baris Akdemir, Alejandra Gutierrez, Jane Chen, Univ of Minnesota, Minneapolis, MN; Selcuk Adabag, Minneapolis VA Medical Ctr, Minneapolis, MN

1:30 PM

Board # 2111

The Better Prognosis of Heart Failure With Preserved Ejection Fraction Patients Taking Sodium Glucose Cotransporter-2 Inhibitors -Insights From Pursuit-hfpef Registry-

**Koichi Inoue** , Sakurabashi Watanabe Hosp, Osaka, Japan; Yoshio Yasumura, Amagasaki Chuo Hosp, Amagaski, Japan; Takahisa Yamada, Osaka General Medical Ctr, Osaka, Japan; Masaaki Uematsu, Natl Hosp Organization Osaka Natl Hosp, Osaka, Japan; Shunsuke Tamaki, Osaka General Medical Ctr, Osaka, Japan; Yoshiharu Higuchi, Osaka Police Hosp, Osaka, Japan; Yusuke Nakagawa, Kawanishi City Hosp, Kawanishi, Japan; Hisakazu Fuji, Kobe Ekisaikai Hosp, Kobe, Japan; Masami Nishino, Osaka Rosai Hosp, Sakai, Japan; Shungo Hikoso, Osaka Univ Grad Sch of Med, Suita, Japan; Daisaku Nakatani, Osaka Univ Graduate Sch, Suita, Japan; Yasushi Sakata, Osaka Univ Grad Sch Med, Suita, Japan; Masato Okada, Toshinari Onishi, Sakurabashi Watanabe Hosp, Osaka, Japan; Katsuomi Iwakura, Sakurabashi Waturahe Hospi, Osaka, Japan; Kenshi Fujii, Sakurabashi Watanabe Hosp, Osaka, Japan

1:30 PM

Board # 2112

Circulating microRNA 362-3p is Associated With Increased Sensitivity to Drug-Induced QT Interval Lengthening

Abdullah Assiri, Elena Muensterman, James E Tisdale, Heather A Jaynes, Purdue Univ, Indianapolis, IN; Richard Kovacs, IU Sch of Med and IU Health, Indianapolis, IN; Kevin M Sowinski, **Brian R Overholser** , Purdue Univ, Indianapolis, IN

1:30 PM

Board # 2113

Impact of Early and Late Ventricular Tachycardia in Patients With Continuous Flow Left Ventricular Assist Devices: A Systematic Review and Metaanalysis

**Rakesh Gopinathannair** , Sharan Sharma, Donita Atkins, Kansas City Heart Rhythm Inst, Overland Park, KS; Jaimin Trivedi, Mark S Slaughter, Univ of Louisville, Louisville, KY; Brian Olshansky, Mercy Hosp, Mason City, IA; Yoaav Krauthammer, Ochsner Clinic Fndn, New Orleans, LA; Dhanunjaya Lakkireddy, Kansas City Heart Rhythm Inst, Leawood, KS

1:30 PM

Board # 2115

Machine Learning Prediction of Cardiac Resynchronization Therapy Response Using 12-Lead QRS Waveform Changes After Biventricular Pacing

**Albert K Feeny** , Case Western Reserve Univ, Cleveland, OH; John Rickard, Cleveland Clinic Fndn, Cleveland Hts, OH; Kevin M Trulock, Cleveland Clinic Fndn, Cleveland, OH; Divyang Patel, Cleveland Clinic, Cleveland, OH; Saleem Toro, Cleveland Clinic Fndn, Cleveland Heights, OH; Niraj Varma, Cleveland Clinic, Cleveland, OH; Mark J Niebauer, Cleveland Clinic Fndn, Cleveland, OH; Mina K Chung, Cleveland Clinic, Cleveland, OH; Anant Madabhushi, Case Western Reserve Univ, Cleveland, OH

1:30 PM

Board # 2116

Increased Beat-to-Beat Variability of T-Wave Heterogeneity Measured From 12-Lead Electrocardiogram is Associated With Sudden Cardiac Death: A Case-Control Study

**Jenni Hekkanen** , Univ of Oulu, Oulu Univ Hosp, Oulu, Finland; Tuomas Kentta, Univ of Oulu, Oulu, Finland; Anette Haukilahti, Medical Res Ctr Oulu, Unive, Oulu, Finland; Lauri Holmstrom, Univ of Oulu, Oulu Univ Hosp, Oulu, Finland; Juha Vahatalo, Univ of Oulu, Oulu, Finland; Janne Rahola, Mikko Tulppo, Antti Kiviniemi, Olavi Ukkola, Univ of Oulu, Oulu Univ Hosp, Oulu, Finland; Juhani Junttila, Univ of Oulu, Oulu, Finland; Heikki Huikuri, Oulu Univ Hosp, Los Angeles, CA; Juha Perkiomaki, Univ of Oulu, Oulu, Finland

1:30 PM

Board # 2117

JT Interval Prolongation and Risk of Cardiovascular Mortality

**Reza Mohebi** , Icahn Sch of Med at Mount Sinai, New York, NY; Aaron Grober, Univ of California San Francisco, San Francisco, CA; Ayesha Jehan, VA Palo Alto Health Care System, Stanford Univ, Palo Alto, CA; Victor Froelicher, Stanford Univ, Stanford, CA

1:30 PM

Board # 2118

Predictors of ICD Shocks Post Left Ventricular Assist Device Implantation

**Jaimin Trivedi** , Univ of Louisville, Louisville, KY; Henri Roukoz, Univ Minnesota, Minneapolis, MN; Adarsh Bhan, Advocate Christ Medical Ctr, Oak Lawn, IL; Mustafa Ahmed, Univ of Florida, Gainesville, FL; Geetha Bhat, Advocate Christ Medical Ctr, Oak Lawn, IL; Ashwin Ravichandran, Saint Vincent Hosp, Indianapolis; Jennifer Cowger, St. Vincent Heart Ctr, Indianapolis, IN; Rahul Dhawan, Univ of Nebraska, Omaha, NE; Rajakrishnan Vijayakrishnan, Mark S Slaughter, Univ of Louisville, Louisville, KY; Rakesh Gopinathannair, Kansas City Heart Rhythm Inst, Overland Park, KS

# Abstract Poster Session

## AT.APS.23 - Atherosclerosis Initiation and Differentiation

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Elizabeth J Tarling, Los Angeles, CA

1:30 PM

Board # 1083

Nicotine Exacerbates Atherosclerosis and Plaque Instability via Lysosome Dysfunction-Mediated NLRP3 Inflammasome Activation

**Ye Ding** , Junqing An, Georgia State Univ, Atlanta, GA; Yi Han, Jiangsu Province Hosp, Nanjing; Sean Michael Carr, Ping Song, Ming-hui Zou, Georgia State Univ, Atlanta, GA

1:30 PM

Board # 1084

Cigarette Smoke Induced Atherosclerotic Plaques Drive Aortic Wall Degeneration and Abdominal Aortic Aneurysms

**Takuo Emoto** , Toronto General Res Inst, Univ Health Network, Toronto, ON, Canada; Danya Thayaparan, McMaster Univ, Hamilton, ON, Canada; Rickvinder Besla, Edouard Al-Chami, Angela Li, Shaun Pacheco, Felix Chiu, Toronto General Res Inst, Univ Health Network, Toronto, ON, Canada; Martin Stampfli, McMaster Univ, Hamilton, ON, Canada; Clint Robbins, Toronto General Res Inst, Univ Health Network, Toronto, ON, Canada

1:30 PM

Board # 1085

A Self-Antigen Identified by Immuno-peptidomic Studies of Coronary Artery Disease Patients is Potentially Involved in Atherosclerosis With Sex as Determinant of Disease Outcome

**Paul C Dimayuga** , Wai Man Lio, Bojan Cercek, Juliana Yano, Wei Yang, Jonathan Ghermezi, Xiaoning Zhao, Jianchang Zhou, Bo Zhou, Michael R Freeman, Kuang-Yuh Chyu, Prediman K Shah, Cedars-Sinai Medical Ctr, Los Angeles, CA

1:30 PM

Board # 1086

The Interplay Between Leukocyte Integrin Mac-1 And Estrogen Receptors Protects Against Atherosclerosis

**Elzbieta Pluskota** , Dorota Szpak, Cleveland Clinic, Cleveland, OH; Lahoucine Izem, Cleveland Clinic Fndn, Cleveland, OH; Dmitriy Verbovetskiy, Dmitry Soloviev, Cleveland Clinic, Cleveland, OH; Edward F Plow, Lerner Res Inst Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 1087

Thickened Intimas and High Densities of Macrophages are Required for Necrosis in Arterial Sections: Towards a General Computational Framework

**Navid Mohammad Mirzaei** , Pak-Wing Fok, Univ of Delaware, Newark, DE

1:30 PM

Board # 1088

The LDL Receptor-independent Effects of Proprotein Convertase Subtilisin Kexin 9 (PCSK9) on T Cell Programming and the Development of Atherosclerosis

Young Uk Kim, McGovern Medical Sch, UTHealth, Houston, TX; **Patrick Kee** , Delia C Danila, UTHSC-Houston, Houston, TX; Yeonseok Chung, Seoul Natl Univ, Seoul, Korea, Republic of; Ba-Bie Teng, McGovern Medical Sch, UTHealth, Houston, TX

1:30 PM

Board # 1089

Autoantibodies to the Angiotensin II Type 1 Receptor Contribute to Arteriolosclerosis Through Inhibition of BK Channels

**Meili Wang** , Xiaochen Yin, Suli Zhang, Huirong Liu, Capital Medical Univ, Beijing, China

1:30 PM

Board # 1090

Low Levels of Lysosomal Acid Lipase Contribute to Arterial Smooth Muscle Foam Cell Formation in Atherosclerosis

**Joshua A Dubland** , Univ of British Columbia, Vancouver, BC, Canada; Sima Allahverdian, Ctr for Heart Lung Innovation, Vancouver, BC, Canada; Ying Wang, Stanford Univ, E Palo Alto, CA; Collin S. Pryma, Carleena Ortega, Kamel Boukais, Katrina Besler, Michael A Seidman, Teddy Chan, Gordon A Francis, Univ of British Columbia, Vancouver, BC, Canada

1:30 PM

Board # 1091

Clonally-Expanding Smooth Muscle Cells Promote Atherosclerosis by Escaping From Efferocytosis and Activating the Complement Cascade

**Ying Wang** , Dan Direnzo, Vivek Nanda, Jianqin Ye, Sophia Xiao, Yoko Kojima, Stanford Univ, Stanford, CA; Kathryn L Howe, Stanford Univ, Toronto, ON, Canada; Kai-Uwe Jarr, Stanford Univ, Stanford, CA; Alyssa M Flores, Stanford Univ, Palo Alto, CA; Pavlos Tsantilas, Noah Tsao, Robert C Wirka, Abhiram Rao, Stanford Univ, Stanford, CA; Alexandra Newman, Univ of Virginia, Charlottesville, VA; James Priest, Stanford Univ, Palo Alto, CA; Arno Ruusalepp, Tartu Univ Hosp, Tartu, Estonia; Gerard Pasterkamp, UMCU, Utrecht; Lars Maegdefessel, Technical Univ Munich, Muich, Germany; Clint Miller, Univ of Virginia, Charlottesville, VA; Irving Weissman, Stanford Univ, Stanford, CA; Lars Lind, Univ Hosp, Uppsala, Sweden; Simon Koplev, Icahn Sch of Med at Mount Sinai, New York, NY; Johan LM Björkegren, Icahn Shool om Med at Mount Si, Nyc, NY; Gary K Owens, Univ Virginia, Charlottesville, VA; Erik Ingelsson, Nicholas J Leeper, Stanford Univ, Stanford, CA

1:30 PM

Board # 1092

**Carbon Tetrachloride Injection Induces Liver Fibrosis in Apoe** -/- **Mice and Increases Atherosclerosis Using a Model of Accelerated Atherosclerosis**

Yu Wang, He-Ying Sun, **Amir Rezvan** , Emory Univ, Atlanta, GA

# Abstract Poster Session

## EA.APS.31 - Atrial Fibrillation - Risk Stratifiers and Advances in Diagnostics

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2085

Left Atrial Appendage Thrombus and Stroke in Cancer Patients With Atrial Fibrillation

Kunal Shah, Ali Syed Musadiq, Nada B Memon, Jose Banchs, **Kaveh Karimzad** , MD Anderson Cancer Ctr, Houston, TX

1:30 PM

Board # 2086

Impact of Atherosclerotic Disease on Cardiovascular Events in Atrial Fibrillation Patients: The Fushimi Af Registry

**Nobutoyo Masunaga** , Kenjiro Ishigami, Yuya Aono, Syuhei Ikeda, Kosuke Doi, Yoshimori An, Mitsuru Ishii, Moritake Iguchi, Kyoto Medical Ctr, Kyoto, Japan; Masahiro Esato, Ljinkai Takeda General Hosp, Kyoto, Japan; Hiromichi Wada, Koji Hasegawa, Hisashi Ogawa, Mitsuru Abe, Masaharu Akao, Kyoto Medical Ctr, Kyoto, Japan

1:30 PM

Board # 2087

Elevation of Neutrophil to Lymphocyte Ratio and Monocyte to Lymphocyte Ratio Are Associated With Recurrence of Atrial Fibrillation After Pulmonary Vein Isolation

**Masamichi Yano** , Masami Nishino, Hiroaki Nohara, Taku Toyoshima, Naoko Higashino, Kohei Ukita, Akito Kawamura, Kyosuke Yanagawa, Hitoshi Nakamura, Yutaka Matsuhiro, Koji Yasumoto, Naotaka Okamoto, Akihiro Tanaka, Yasuharu Matsunaga, Daisuke Nakamura, Masaki Yamato, Yasuyuki Egami, Ryu Shutta, Jun Tanouchi, Osaka Rosai Hosp, Sakai, Japan

1:30 PM

Board # 2088

Factors Associated With Changes in Quality of Life Among Atrial Fibrillation Patients in Real-World Clinical Practice: Findings From the Prospective Canadian SPRINT-AF Registry

**Andrew C Ha** , Peter Munk Cardiac Ctr, Toronto, ON, Canada; Christopher Labos, McGill Univ, Montreal, QC, Canada; Paul Dorian, St Michaels Hosp, Toronto, ON, Canada; GB John Mancini, Univ of British Columbia, Vancouver, BC, Canada; Jafna L Cox, Dalhousie Univ, Halifax, NS, Canada; David J. Gladstone, Univ of Toronto, Toronto, ON, Canada; Evan E Lockwood, Victoria Cardiac Arrhythmia Trials, Edmonton, AB; Narendra Singh, Atlanta Heart Specialist, Cumming, GA; Ashfaq Shuaib, Univ of Alberta Hosp Site, Edmonton, AB, Canada; Michelle Padarath, Milan Gupta, Canadian Collabortive Res Network, Brampton, ON, Canada

1:30 PM

Board # 2089

Heat Shock Protein 70 is Associated With Cardioversion Outcome and Recurrence of Symptomatic Recent Onset Atrial Fibrillation in Hypertensive Patients

**James N Tsoporis** , St. Michael's Hosp, Toronto, ON, Canada; Angelos G Rigopoulos, Univ of Athens Medical Sch, Attikon Univ Hosp, Athens, Greece; Ioannis Rizos, Univ of Athens medical Sch, Attikon Univ Hosp, Athens, Greece; Andreas Kalogeropoulos, Andreas S Triantafyllis, Univ of Athens Medical Sch, Attikon Univ Hosp, Athens, Greece; Shehla Izhar, Thomas Parker, St. Michael's Hosp, Toronto, ON, Canada

1:30 PM

Board # 2090

New Onset Atrial Fibrillation After Stem Cell Transplantation - 10 Year Experience at MD Anderson Cancer Center

Kunal Shah, **Ali Syed Musadiq** , Juhee Song, Syed Wamique Yusuf, Muzaffar Qazilbash, Kaveh Karimzad, MD Anderson Cancer Ctr, Houston, TX

1:30 PM

Board # 2091

Efficacy of Novel Patch Type Device for Screening Silent Atrial Fibrillation

**Yousaku Okubo** , Yukiko Nakano, Ikeuchi Yoshihiro, Hiroshima Univ, Hiroshima, Japan; Shunsuke Miyauchi, Hiroshima Univ Hosp, Hiroshima, Japan; Sho Okamura, Hiroshima Univ Hosp, Hiroshima-shi, Japan; Naoya Hironobe, Hiroshima Univ, Hiroshima, Japan; Takehito Tokuyama, Hiroshima Univ Hosp, Hiroshima, Japan; Yasuki Kihara, Hiroshima Univ, Hiroshima, Japan

1:30 PM

Board # 2092

Left Atrial Size is Superior to Left Ventricular Ejection Fraction in Predicting Mortality Among Patients With Atrial Fibrillation

Athanasios Samaras, Anastasios Kartas, George Fotos, George Dividis, Dimitra Vasdeki, Eleni Paschou, Evropi Forozidou, Paraskevi Tsoukra, Eleni Kotsi, George Efthimiadis, Haralambos Karvounis, Apostolos Tzikas, **George Giannakoulas** , Ahepa Univ Hosp, Thessaloniki, Greece

# Abstract Poster Session

## EA.APS.34 - Atrial Fibrillation Diagnostic Monitoring

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2119

Medical Floor Loop Recorder Implantation: Investigating Outcomes

**Alicia Chionchio** , Beom Soo Kim, David Chang, Arvind Devanabanda, Apoor Patel, Jonathan Willner, Stuart Beldner, Laurence Epstein, Northwell Health, Manhasset, NY

1:30 PM

Board # 2120

Implantable Loop Recorders: Sensitive but Not Specific

**Mustafa AlQaysi** , Navid Berenji, Jennifer Logan, Stacy Saldivar, Manoj Panday, Auroa Badin, UT Health San Antonio, San Antonio, TX; Dhanunjaya Lakkireddy, Univ of Kansas Health System, Kansas City, KS; Arun Sridhar, Univ of Washington Sch of Med, Seattle, WA; Jayasree Pillarisetti, UT Health San Antonio, San Antonio, TX

1:30 PM

Board # 2121

Projected Economic Implications of Varying Positive Predictive Values for Atrial Fibrillation Episodes Among Insertable Cardiac Monitors in the United States

**John D Rogers** , Scripps Clinic, La Jolla, CA; Sarah C Rosemas, Medtronic, Mounds View, MN; Stelios I Tsintzos, Medtronic, Inc., Mounds View, MN

1:30 PM

Board # 2122

Economic Impact of Increased Longevity in Insertable Cardiac Monitor Technology in Unexplained Syncope and Suspected Atrial Fibrillation Patients

**Klaus K Witte** , Univ of Leeds, Leeds, United Kingdom; Laura M Sawyer, Sarah L Bermingham, Claudia Rinciog, Symmetron Limited, London, United Kingdom; Sarah C Rosemas, Stelios I Tsintzos, Medtronic, Inc., Mounds View, MN; Matthew R Reynolds, Baim Inst, Boston, MA

1:30 PM

Board # 2123

Cardioversion Outcomes After Left Atrial Appendage Occlusion With the Watchman Device

**Simrat Kaur** , Cleveland Clinic, Cleveland, OH; Erika Hutt, Cleveland Clinic Fndn, Cleveland, OH; Walid I Saliba, Mohamed H Kanj, Khaldoun Tarkaji, Cleveland Clinic, Cleveland, OH; Bryan Baranowski, Cleveland Clinic Fndn, Cleveland; Daniel J Cantillon, Cleveland Clinic, Cleveland, OH; John Rickard, Cleveland Clinic, Cleveland Hts, OH; Thomas J Dresing, Cleveland Clinic Fndn, Cleveland, OH; Thomas D Callahan IV, Mandeep Bhargava, Oussama Musbah Wazni, Samir R Kapadia, Cleveland Clinic, Cleveland, OH; Ayman Hussein, Cleveland Clinic Fndn, Cleveland

1:30 PM

Board # 2124

Reduction in Atrial Fibrillation Burden Following Catheter Ablation: Results From the Reveal LINQ Real-world Registry

**Suneet Mittal** , The Valley Hosp Health System, Paramus, NJ; Hans-Christoph Diener, Univ Duisburg-Essen, Essen, Germany; Scott E Kasner, Univ of Pennsylvania, Philadelphia, PA; Atul Verma, Southlake Regional Health Ctr, Newmarket, ON, Canada; Sean C Beinart, Washington Adventist Hosp, Rockville, MD; Alpesh N Amin, Univ of California - Irvine, Orange, CA; Erika Pouliot, Noreli C Franco, Medtronic, Mounds View, MN; Andrea Natale, St. David's Medical Ctr, Austin, TX

1:30 PM

Board # 2125

Diagnostic Accuracy of the Confirm RX Internal Loop Recorder for Atrial Fibrillation Detection

**Carola Gianni** , Texas Cardiac Arrhythmia Inst, Austin, TX; Andrew Vu, Arrhythmia Service, San Francisco, CA; Uğur Canpolat, Hüseyin Ayhan, Chen Qiong, Bryan MacDonald, Domenico G Della Rocca, Sanghamitra Mohanty, Chintan Trivedi, Amin Al-Ahmad, Mohamed Bassiouny, J David Burkhardt, G Joseph Gallinghouse, Patrick M Hranitzky, Rodney P Horton, Javier Sanchez, Luigi Di Biase, Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

1:30 PM

Board # 2126

Prognostic Impact of Anemia on Stroke/Systemic Embolism, Bleeding, and Mortality in Patients With Atrial Fibrillation: The Fushimi AF Registry

**Yoshimori An** , Moritake Iguchi, Mitsuru Ishii, Nobutoyo Masunaga, Yuya Aono, Syuhei Ikeda, Kenjiro Ishigami, Kyoto Medical Ctr, Kyoto, Japan; Kosuke Doi, Kyoto Medical Ctr, Fushimi-ku,Kyoto, Japan; Masahiro Esato, Ljinkai Takeda General Hosp, Kyoto, Japan; Hikari Tsuji, Tsuji Clinic, Kyoto, Japan; Hiromichi Wada, Koji Hasegawa, Hisashi Ogawa, Mitsuru Abe, Masaharu Akao, Kyoto Medical Ctr, Kyoto, Japan

1:30 PM

Board # 2127

Detection of Atrial Fibrillation With a Portable Device During Cardiovascular Disease Screening in Primary Care: Data From the PROVAR + Study

Adriana C Diamantino, Rua Herculano De Freitas 151, Belo Horizonte Mg, Brazil; **Bruno R Nascimento** , Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Andrea Z Beaton, Cincinnati Childrens Hosp Medic, Cincinnati, OH; Maria Do Carmo Pereira Nunes, UFMG, Belo Horizonte, Brazil; Kaciane K Oliveira, Lara C Rabelo, Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Marcia Barbosa, Hosp Socor, Belo Horizonte, Brazil; Alison T Reese, Children´s Natl Health System, Washington, DC; Laura Olivieri, Children's Natl Medical Ctr, Washington, DC; Mariana D Mata, João Pedro P Rios, Augusto F Pereira, Luciana C Diamantino, Hosp das Clínicas da Univ Federal de Minas Gerais, Belo Horizonte, Brazil; Antonio L Ribeiro, UFMG, Belo Horizonte, Brazil; Craig A Sable, Children's Natl Medical Ctr, Potomac, MD; Luisa C Brant, Federal Univ of Minas Gerais, Belo Horizonte, Brazil

1:30 PM

Board # 2128

Implantable Loop Recorders in Contemporary Practice: Can Clinical or Ecg Findings Predict an Arrhythmic Origin for Unexplained Syncope?

**Rady Ho** , Daniel Marks, Cooper Univ Hosp, Camden, NJ; Andrea M Russo, Cooper Univ Hosp, Moorestown, NJ; John Andriulli, Matthew Ortman, Cooper Univ Hosp, Camden, NJ

# Abstract Poster Session

## HF.APS.44 - Basic and Translational Insights into Ventricular Function/Cardiomyopathy

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2292

Female Rats Have Better Right Ventricular (RV) Systolic Function Than Male Rats in Pressure Overload Despite Comparable RV Afterload

**Tik-Chee Cheng** , Diana M. Tabima, Univ of Wisconsin - Madison, Madison, WI; Timothy A Hacker, Univ of Wisconsin, Madison, WI; Naomi C. Chesler, Univ of Wisconsin - Madison, Madison, WI

1:30 PM

Board # 2293

Prognostic Significance of Circulating Leukocyte Subtype Counts in Patients With Chronic Heart Failure

**Masafumi Takae** , Eiichiro Yamamoto, Kumamoto Univ Hosp, Kumamoto, Japan; Koichiro Fujisue, Kumamoto Univ, Kumamoto, Japan; Taiki Nishihara, 1-1-1 Honjo Chuo-Ku Kumamoto, Kumamoto, Japan; Fumi Oike, Kumamoto Univ Hosp, Kumamoto city, Japan; Daisuke Sueta, Kumamoto Univ Hosp, Kumamoto, Japan; Hiroki Usuku, 1-1-1 Honjo Chuo-Ku Kumamoto, Kumamoto city, Japan; Seiji Takashio, Kumamoto Univ, Kumamoto, Japan; Kenji Sakamoto, Koichi Kaikita, Kenichi Tsujita, Kumamoto Univ Hosp, Kumamoto, Japan

1:30 PM

Board # 2294

Mechanism of the Protective Effects of L-carnitine on Left Ventricular Dysfunction after Short-term Oral Alcohol Administration in Rats

**Zhi Zhang** , Che Ping Cheng, Satoshi Masutani, Tiankai Li, Heng-Jie Cheng, Wake Forest Sch of Med, Winston-Salem, NC

1:30 PM

Board # 2295

Comparison of Clinical Significance of Novel Reactive Oxygen Species Biomarker Among New Categories of Non-ischemic Heart Failure

**Taiki Nishihara** , Eiichiro Yamamoto, Daisuke Sueta, Koichiro Fujisue, Hiroki Usuku, Fumi Oike, Masafumi Takae, Takashi Komorita, Seiji Takashio, Kenji Sakamoto, Koichi Kaikita, Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

1:30 PM

Board # 2296

**Association of Aldh2** **Gene Polymorphism With Cardiac Function Insufficiency After Myocardial Infarction in Chinese Han Population**

**Lijie Wang** , Yu Haiyi, Wei Gao, Peking Univ Third Hosp, Beijing, China

1:30 PM

Board # 2297

Decrease in Fibrosis 4 Index is Associated With Decrease in NT-pro BNP in Patients With Acute Heart Failure

**Takashi Yamada** , Satoru Sakuragi, Mitsutaka Nakashima, Iwakuni Clinical Ctr, Iwakuni, Japan

1:30 PM

Board # 2298

Cardiac Iron Concentration in Relation to Systemic Iron Status and Disease Severity in Dilated Cardiomyopathy

**Valentin G. Hirsch** , Jörn Tonges, Hannover Medical Sch, Hannover, Germany; Julia Bode, Technische Univ Bergakademie, Freiberg, Germany; Dominik Berliner, Julian D. Widder, Hannover Medical Sch, Hannover, Germany; Felicitas Escher, Charite Berlin, Berlin, Germany; Vitalii Mutsenko, Leibniz Univ, Hannover, Germany; Bomee Chung, Fatemeh Rostami, Anja Guba-Quint, Hannover Medical Sch, Hannover, Germany; Evangelos Giannitsis, Univ of Heidelberg, Heidelberg, Germany; Heinz-Peter Schultheiss, Inst Kardiale Diagnostik und Therapie, Berlin; Carla Vogt, Technische Univ Bergakademie, Freiberg, Germany; Johann B Bauersachs, Medische Hochschule Hannover, Hannover, LA; Kai C Wollert, Hannover Medical Sch, Hannover, KS; Tibor Kempf, Hannover Medical Sch, Hannover, Germany

1:30 PM

Board # 2299

Positive Modulation of Exogenous L-carnosine on Left Ventricular Systolic and Diastolic Performance in Conscious, Chronically-Instrumented Dogs With Pacing-Induced Heart Failure: Assessment by Left Ventricular Pressure-Volume Analysis

**Tiankai Li** , Hideo Tachibana, Tomohiko Ukai, Zhi Zhang, Xiaowei Zhang, Nobuyuki Ohte, Heng-Jie Cheng, David Herrington, David Zhao, Che Ping Cheng, Wake Forest Sch of Med, Winston-Salem, NC

1:30 PM

Board # 2300

Exercise-Induced Disproportionate Elevation of Left Ventricular End-Diastolic Pressure vs Pulmonary Artery Diastolic Pressure is Associated With Exercise Intolerance After Myocardial Infarction

**Michinari Hieda** , UT Southwestern Medical Ctr, Dallas, TX; Shinji Yasuno, Kyoto Univ, Kyoto, Japan; Noritoshi Nagaya, Nagaya Clinic, Suita, Japan; Hiroshi Takaki, Takaki Clinic, Suita, Japan; Yoichi Goto, Yoka Municipal Hosp, Yabu City Hyogo, Japan

1:30 PM

Board # 2301

Inflammatory Activity Correlates With Severity of Heart Failure - The Association of High Sensitive CRP With Left Ventricular Ejection Fraction, ProBNP and NYHA-Class in a Real-World Cohort

**Alexander Peikert** , Univ Heart Ctr Freiburg, Freiburg Im Breisgau, Germany; Klaus Kaier, Univ of Freiburg, Freiburg Im Breisgau, Germany; Lucas Steffens, Andreas Clemens, Univ Heart Ctr Freiburg, Freiburg Im Breisgau, Germany; Christoph Bode, Univ Heart Ctr Freiburg, Freiburg, Germany; Andreas Zirlik, Medical Univ Graz, Graz; Peter Stachon, Univ Heart Ctr Freiburg, Freiburg, Germany

1:30 PM

Poster Professor

Barry London, Iowa City, IA

# Abstract Poster Session

## AC.APS.16 - Biomarkers IV

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4109

Kinetic of High-Sensitivity Cardiac Troponin T in Patients With Non ST-Segment Elevation Myocardial Infarction

**Roberto Spoladore** , Giulio Falasconi, Antonio Boccellino, Massimo Slavich, Alberto Maria Cappelletti, Gabriele Fragasso, Alberto Margonato, IRCCS San Raffaele Univ Hosp, Milan, Italy

1:30 PM

Board # 4110

Epigenetic Biomarkers for Assessment of Post-Stroke Recovery

**Shaoling Huang** , Univ of Texas Houston, Houston, TX; Wei Guo, Zymo Reserach Corporate, Irvine, CA; Xing Yin, Univ of Texas Houston, Houston, TX; Manoj Pandurang Dandekar, Univ of Texas Health Science Ctr, Houston, TX; Tao Peng, UTHealth-McGovern Medical Sch, Houston, TX; Melvin E Klegerman, Univ Texas Health Sci Ctr, Houston, TX; Melanie R Moody, UT Health Science Ctr Houst, Houston, TX; Hyunggun Kim, Sungkyunkwan Univ, Suwon; Jaroslaw A Aronowski, Univ of Texas HSC Houston, Houston, TX; David D McPherson, Univ of Texas Health Science, Houston, TX; Keith Booher, Zymo Reserach Corporate, Irvine, CA

1:30 PM

Board # 4111

Evaluating Serum Concentrations of Advanced Glycation Endproducts as a Predictor of Coronary Artery Disease

**Arber Kodra** , Craig Basman, Umar Rashid, Avtanski Dimiter, Chen Karin, Rebecca Jonas, Leonid Poretsky, Singh Varinder, Lenox Hill Hosp, New York, NY

1:30 PM

Board # 4112

Serum Free Fatty Acid Composition as a Critical Regulator for Cardiac Fibroblast Growth Factor 21 Production in Patients With Acute Myocardial Infarction

**Hiroaki Sunaga** , Gunma Univ Graduate Sch of Med, Maebashi, Japan; Norimichi Koitabashi, Gunma Univ Sch Med, Maebashi Gunma, Japan; Hiroki Matsui, Gunma Univ, Maebashi, Japan; Tatsuya Iso, Gunma Univ Graduate Sch Med, Maebashi Gunma, Japan; Nozomi Furukawa, Gunma Univ, Maebashi, Japan; Ryo Kawakami, Gunma Univ, Maebashi, Gunma, Japan, Japan; Tomoyuki Yokoyama, Gunma Univ, Maebashi, Japan; Masahiko Kurabayashi, Gunma Univ Graduate Sch of Med, Gunma, Japan

1:30 PM

Board # 4113

Decreased Level of the Soluble Form of the Receptor for Advanced Glycation End Products is Associated With Increased Risk for Coronary Artery Disease in Non-Diabetic Patients

George Tsirebolos, Attikon Univ Hosp, Athens, Greece; **James N Tsoporis** , Saint Michaels Hosp, Toronto, ON, Canada; Angelos G. Rigopoulos, Elefterios Sakadakis, Attikon Univ Hosp, Athens, Greece; Thomas G Parker, St. Michael's Hosp, Toronto, ON, Canada; Aimilios Simoudis, Attikon Univ Hosp, Athens, Greece; Ioannis Constantin Rizos, Univ of Athens, Athens

1:30 PM

Board # 4114

Initial Experience With The 5th Generation Troponin T In A Large Tertiary Hospital

**Thomas Welch** , Anita Chen, Scott McNitt, Andrew Mathias, John D Bisognano, Univ of Rochester, Rochester, NY

1:30 PM

Board # 4115

Adenosine Plasmatic Concentration in Coronary Artery Disease Patients With and Without Chronic Kidney Disease

**Andre Franci** , Insto do Coracao (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, USP, Sao Paulo, Brazil; Carlos Barbosa, Hosp do Coração Do Brasil, Brasilia, Brazil; Talia Dalcoquio, Rocio Salsoso, Insto do Coracao (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, USP, Sao Paulo, Brazil; Remo H Furtado, Brigham and Women's Hosp, Brookline, MA; Celia Strunz, Insto do Coracao (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, USP, Sao Paulo, Brazil; Paulo Genestreti, Insto do Coracao (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, USP, Sao Paulo, Brazil, Sao Paulo, Brazil; Viviane Lima, Marco Scanavini, Insto do Coracao (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, USP, Sao Paulo, Brazil; Aline G Ferrari, Insto do Coracao (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, USP, Sao Paulo, Brazil, S?o Paulo, Brazil; Luciano Baracioli, Jose Carlos Nicolau, Insto do Coracao (InCor), Hosp das Clinicas HCFMUSP, Faculdade de Medicina, USP, Sao Paulo, Brazil, Sao Paulo, Brazil

1:30 PM

Board # 4116

Soluble Programed Cell Death Ligand-1 is Associated With Acute Coronary Syndrome

**Koichiro Fujisue** , Kumamoto Univ, Kumamoto, Japan; Eiichiro Yamamoto, Kumamoto Univ Hosp, Kumamoto, Japan; Daisuke Sueta, Kumamoto Univ, Kumamoto, Japan; Masafumi Takae, Taiki Nishihara, Kumamoto Univ Hosp, Kumamoto, Japan; Fumi Oike, Kumamoto university hospital, Kumamoto city, Japan; Takashi Komorita, Kumamoto Univ, Kumamoto, Japan; Hiroki Usuku, Kumamoto Univ Hosp, Kumamoto city, Japan; Seiji Takashio, Kenji Sakamoto, Koichi Kaikita, Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

1:30 PM

Board # 4117

Physiological Roles of Serum Acylcarnitine Level and Acylcarnitine/free Carnitine Ratio in Patients With Cardiovascular Diseases

Takafumi Nakajima, **Toshiaki Nakajima** , Hironaga Ogawa, Yuusuke Takei, Ikuko Shibasaki, Shotaro Obi, Satoshi Sakuma, Shigeru Toyoda, Dokkyo Medical Univ, Tochigi, Japan; Masao Nishimura, Nishimura Heart Clinic, Ageoshi, Japan; Shichirou Abe, Hirotsugu Fukuda, Teruo Inoue, Dokkyo Medical Univ, Tochigi, Japan

1:30 PM

Board # 4118

Measurements of in vivo Platelet Activation and Aggregation Following Administration of Ticagrelor at the Time of Acute Type 1 Myocardial Infarction in Diabetics and Non-Diabetics

**Narayana Sarma V Singam** , Bahjat AlAdili, Alok R Amraotkar, Amanda Coulter, Siddhesh Kulkarni, Mitra Riten, Andrew P Defilippis, Omar Noori Daham, Univ of Louisville, Louisville, KY

# Abstract Poster Session

## LF.APS.11 - Cardiac Rehabilitation - Applying to Subgroups and Optimizing Outcomes

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3118

Prevalence and Outcomes of Phase 2 Cardiac Rehabilitation Participants With Resistant Hypertension

**Luke Joseph Laffin** , Asad Khan, Cleveland Clinic Fndn, Cleveland, OH; Katherine Lang, Case Western Reserve Univ Sch of Med, Cleveland, OH; Erik H. Van Iterson, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 3120

Cardiac Rehabilitation in Women; Comparison of Enrollment, Adherence and Outcomes Between Heart Failure and Coronary Artery Disease

**Muhammad Baig** , Brown Univ/ Miriam Hosp, Providence, RI; Hafiz Muhammad Imran, Rhode Island Hosp, Providence, RI; Sebhat Erqou, Wen-Chih Wu, Brown Univ, Providence, RI

1:30 PM

Board # 3121

The Influence of Multimorbidity on Cardiorespiratory Fitness and Mortality in Patients Completing Cardiac Rehabilitation

**Cemal Ozemek** , Deepika Laddu, Univ of Illinois at Chicago, Chicago, IL; Trina Hauer, Total Cardiology Rehabilitation, Calgary, AB, Canada; Codie Rouleau, Tavis Campbell, Stephen Wilton, Univ of Calgary, Calgary, AB, Canada; sandeep Aggarwal, Univ of Calgary, calgary, AB, Canada; Leslie Austford, TotalCardiology, Calgary, AB, Canada; Ross Arena, Univ of Illinois at Chicago, Chicago, IL

1:30 PM

Board # 3122

Neighborhood Factors Influence Early Termination of Cardiac Rehabilitation

**John A Bostrom** , Hong Gao, Jonathan Whiteson, Greg Sweeney, Alicia Pierre, Ana Mola, Thomas Kirchner, John A Dodson, New York Univ, New York, NY

1:30 PM

Board # 3123

The Relationship Between Early Cardiac Rehabilitation and Long-term Outcomes in a Post Cabg Population - A Clinical and Administrative Database Study

**Reena Karkhanis** , Harindra C Wijeysundera, Derrick Y Tam, Sunnybrook Health Sciences Ctr, Toronto, ON, Canada; Paul Oh, Toronto Rehabilitation Inst,UHN, Toronto, ON, Canada; David Alter, Alex Kiss, Inst for Clinical Evaluative Sciences, Toronto, ON, Canada; Stephen Fremes, Sunnybrook Health Sciences Ctr, Toronto, ON, Canada

1:30 PM

Board # 3124

The Prognostic Benefit of Completing Phase 2 Cardiac Rehabilitation in Heart Failure Does Not Depend on Left Ventricular Ejection Fraction

**Erik H Van Iterson** , Asad Khan, Taha Ahmed, Luke J Laffin, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 3125

Derivation and Validation of a Score System to Stratify Post-op Valvular Patients in Cardiac Rehab

Francesco Maranta, Anna Pistoni, Iside Cartella, Lorenzo Cianfanelli, San Raffaele Hosp, Milano, Italy; Paolo Cerea, Univ of Milano Bicocca, Monza, Italy; Stefania Sacchi, Maria Grazia Pala, Maria Avitabile, Carlo Meloni, San Raffaele Hosp, Milano, Italy; Michele De Bonis, Vita-Salute San Raffaele Univ, Milano, Italy; Alessandro Castiglioni, Ottavio Alfieri, San Raffaele Hosp, Milano, Italy; **Domenico Cianflone** , Vita-Salute San Raffaele Univ, Milano, Italy

1:30 PM

Board # 3126

Characteristics and Relative Improvements in Clinical Cardio Metabolic Profiles Among Adults With and Without Type 2 Diabetes Participating in a Cardiac Rehabilitation Program

**Deepika Laddu** , Univ of Illinois Chicago, Chicago, IL; Cemal Ozemek, Univ of Illinois at Chicago, Chicago, IL; Trina Hauer, TotalCardiologyTM-Rehabilitation, Calgary, Alberta, Canada, Calgary, AB, Canada; Codie R Rouleau, TotalCardiologyTM, Calgary, AB, Canada; Tavis Campbell, Stephen Wilton, Sandeep Aggarwal, Univ of Calgary, Calgary, AB, Canada; Leslie Austford, TotalCardiologyTM, Calgary, AB, Canada; Ross Arena, Univ of Illinois Chicago, Chicago, IL

1:30 PM

Poster Professor

Kushal Madan, New Delhi, India

1:30 PM

Board # 3127

Exercise for Patients With Hypertrophic Cardiomyopathy

**Atsuko Nakayama** , Hiroyuki Morita, The Univ of Tokyo, Tokyo, Japan; Masatoshi Nagayama, Sakakibara Heart Inst, Tokyo, Japan; Mitsuaki Isobe, Sakaibara Heart Inst, Tokyo, Japan; Issei Komuro, The Univ of Tokyo, Tokyo, Japan

# Abstract Poster Session

## HF.APS.46 - Cardiomyopathy: Hypertrophic and Amyloid

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2313

Quality of Life and Exercise Performance in Low Risk Hypertrophic Cardiomyopathy: VANISH Ancillary Study

**Danielle Burstein** , Children's Hosp of Philadelphia, Philadelphia, PA; Antara Mondal, Children's Hosp of Philadelphia, King of Prussia, PA; Jungwon Min, CHOP, Huntingdon Vy, PA; Jen Faerber, CHOP, Huntingdon Vy, PA, Philadelphia, PA; Joseph William Rossano, Children's Hosp of Philadelphia, Haverford, PA; Carolyn Ho, Brigham and Women's Hosp, Boston, MA; Renee E Margossian, Steven D Colan, Boston Children's Hosp, Boston, MA; Matthew J O'Connor, Univ of Pennsylvania, Philadelphia, PA; Jonathan H Soslow, Vanderbilt Univ Medical Ctr, Nashville, TN; Larry W Markham, Riley Hosp for Children, Indianapolis, IN; Thomas Disalvo, Medical Univ of South Carolina, Charleston, SC; Harry M Lever, Cleveland Clinic, Solon, OH; Kenneth G Zahka, Cleveland Clinic Fndn, Cleveland, OH; Ivan Wilmot, Cincinnati Childrens Hosp, Cincinnati, OH; Juli Sublett, Cincinnati Children's Hosp, Cincinnati, OH; Mark W Russell, Univ of Michigan, Ann Arbor, MI; Sharlene Day, Univ of Pennsylvania, Philadelphia, PA; Amit Patel, Univ of Chicago, Chicago, IL; Anne M Murphy, Johns Hopkins Univ Sch of Med, Baltimore, MD; Charles E Canter, Richard G Bach, Washington Univ Sch Med, Saint Louis, MO; Luisa Mestroni, Denver Children's Hosp, Aurora, CO; Matthew Taylor, Univ of Colorado Denver, Aurora, CO; Euan A Ashley, Matthew T Wheeler, Stanford Univ, Stanford, CA; Lee Benson, Hosp for Sick Kids, Toronto, ON, Canada; Anjali T Owens, Hosp of the Univ of Pennslyvania, Philadelphia, PA; Elfriede Pahl, Ann & Robert H. Lurie Childs Hosp, Chicago, IL; Philip Thrush, Children's Hosp of Chicago, Chicago, IL; Alexandre Da Costa Pereira, Heart Inst (incor), Sao Paulo, Brazil; Henning Bundgaard, Natl Univ Hosp, Copenhagen, Denmark; Anna Axelsson, Univ of Copenhagen, Boston, MA; Kimberly Y Lin, Children's Hosp of Philadelphia, Philadelphia, PA; VANISH Investigators

1:30 PM

Board # 2314

Reduced Left Ventricular Ejection Fraction and Higher Angiotensin-Converting Enzyme Levels as Key Determinants of Histopathologic Diagnosis by Endomyocardial Biopsy in Patients With Cardiac Sarcoidosis

**Hirokazu Komoriyama** , Kazunori Omote, Toshiyuki Nagai, Yuta Kobayashi, Yoshiya Kato, Takuma Sato, Hokkaido Univ, Sapporo, Japan; Takao Konishi, Hokkaido Unversity, Sapporo, Japan; Tadao Aikawa, Kiwamu Kamiya, Kazuhiro Koyanagawa, Shingo Tsujinaga, Hiroyuki Iwano, Hokkaido Univ, Sapporo, Japan; Hatsue Ueda, Natl Cerebral and Cardiovascular Ctr Hosp, Suita, Osaka, Japan; Toshihisa Anzai, Hokkaido Univ, Sapporo, Japan

1:30 PM

Board # 2315

Atrial Fibrillation in Transthyretin Amyloid Cardiomyopathy May Present With Controlled Ventricular Response: A Retrospective Study

**Lindsey R Mitrani** , Elissa A Driggin, Jeffeny De Los Santos, Stephen Helmke, New York Presbyterian, New York, NY; Mathew S Maurer, New York Presbyterian Hosp, New York, NY

1:30 PM

Board # 2316

Biomarker and Echocardiographic Trends in Cardiac Amyloidosis Patients Managed With Doxycycline

**Eric M Holland** , Univ of North Carolina, Chapel Hill, NC; Grayson Eubanks, Univeristy of North Carolina, Chapel Hill, NC; Daniel Duddleston, Brian C Jensen, Patricia P Chang, Mirnela Byku, Univ of North Carolina, Chapel Hill, NC

1:30 PM

Board # 2317

Differentiation of Cardiac Amyloidosis From Other Causes of Left Ventricular Hypertrophy Based on Holter Monitoring

**Naoko Hijioka** , Shinya Yamada, Amami Kazuaki, Fukushima Medical Univ, Fukushima, Japan; Masashi Kamioka, Fukushima Medical Univ, Fukushima-city, Japan; Takashi Kaneshiro, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

1:30 PM

Board # 2318

Cardiac Sarcoidosis: A United States National Study of In-Hospital Outcomes and 30-Day Readmissions

**Mohammad-Ali Jazayeri** , Univ of Kansas Medical Ctr, Kansas City, KS; Nikita A Umale, Boston Univ, Boston, MA; Venkat Vuddanda, Brigham & Women's Hosp, Boston, MA; Moghniuddin Mohammed, St. Luke's Health System, Kansas City, MO; Seyed Hamed Hosseini Dehkordi, Ioannis Mastoris, Siva Sagar Taduru, Seth H Sheldon, Madhu Reddy, Nicholas Haglund, Andrew J Sauer, Zubair I Shah, Univ of Kansas Medical Ctr, Kansas City, KS

1:30 PM

Board # 2319

Temporal Trend in Age at Diagnosis of Hypertrophic Cardiomyopathy: An Analysis of the Share Registry

Marco Canepa, Univ of Genova, Genova, Italy; **Carlo Fumagalli** , Univ of Florence and AOU Careggi, Firenze, Italy; Giacomo Tini, Univ of Genova, Genova, Italy; Francesco Mazzarotto, Univ of Florence and AOU Careggi, Firenze, Italy; Justin Vincent-Tompkins, Myokardia Inc., San Francisco, CA; Sharlene M Day, Univ of Michigan, Ann Arbor, MI; Euan A Ashley, Stanford Univ, Stanford, CA; Michelle Michels, ERASMUSMC, Rotterdam; Steven D Colan, Boston Children's Hosp, Boston, MA; Daniel Jacoby, Yale Sch of Med, New Haven, CT; Carolyn Ho, Brigham and Women's Hosp, Boston, MA; Iacopo Olivotto, Univ of Florence and AOU Careggi, Florence, Italy; SHaRe Investigators

1:30 PM

Board # 2320

Prosthetic Joint Replacements Are Associated With a Higher Burden of Cardiac and Systemic Sarcoidosis

**Bharat Narasimhan** , Stuthi Perimbeti, Mount Sinai St.Lukes-Roosevelt, New york, NY; Ameesh Isath, Mount Sinai St.Lukes-Roosevelt, Rochester, MN; Lingling Wu, Kirtipal Singh Bhatia, Mount Sinai St Luke's and West, New York, NY; Kam Ho, Mount Sinai St Luke's and West Hosp, New York, NY; Ashish Correa, Mount Sinai St Lukes-West Hosp, New York, NY; Davendra Mehta, Mount Sinai St Luke S Roosevelt Ho, New York, NY

1:30 PM

Board # 2321

Septal Alcohol Ablation versus Myectomy for Hypertrophic Cardiomyopathy

**Ruchit Shah** , Ichan Sch of Med Mt. Sinai St. Luke's and West, New York, NY; Xin Wei, New York, NY; Bing Yue, Mount Sinai St. Luke's-West Hosp, New York, NY; Karan Sud, Mount Sinai St Luke's-West, New York, NY; Swiri Konje, Ichan Sch of Med Mt. Sinai St. Luke's and West, New York, NY; Joseph A Puma, Lenox Hill Heart Vascular Inst, New York, NY

# Abstract Poster Session

## WS.APS.06 - Cardiovascular Care for the Aging Patient

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3092

Multimorbidity Predicts Patient-Centered Outcomes After Cardiac Surgery

**Krish C Dewan** , Cleveland Clinic, Cleveland, OH; Guangjin Zhou, Suparna M Navale, Siran M Koroukian, Nicholas K Schiltz, Case Western Reserve Univ Sch of Med, Cleveland, OH; Marc Gillinov, Edward Gregory Soltesz, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 3091

Rising Trends in Percutaneous Coronary Interventions Among Frail Patients and Worsening In-Hospital Outcomes: A Nationwide Retrospective Analysis of 21,329 Procedures

Rupak Desai, Atlanta VA Medical Ctr, Decatur, GA; **Samarthkumar Jayeshkumar Thakkar** , Rochester General Hosp, Rochester, NY; Manpreet Kaur, Cleveland Clinic Fndn, Cleveland, OH; Mir ZA Khan, St. Peters Univ Hosp, New Brunswick, NJ; Nazia Farheen, Lake America Family Physicians, Clermont, FL; Abhimanyu Ravalani, St. Peters Univ Hosp, New Brunswick, NJ; Kishorbhai Gangani, Texas Health Arlington Memorial, Arlington, TX; Rajesh Sachdeva, Morehouse Sch of Med, Atlanta VA Medical Ctr & Emory Univ Sch of Med, Atlanta, GA; Gautam Kumar, Emory Univ Sch of Med & Atlanta VA Medical Ctr, Decatur, GA

1:30 PM

Board # 3097

Impact of Blood Concentration of the Direct Oral Anticoagulant Apixaban on Clinical Care of Nonagenarians and the Very Old

**Lawrence Baruch** , Olga Sherman, Diana Otero, Persio David Lopez Loyo, Bronx VA Medical Ctr, Bronx, NY

1:30 PM

Board # 3096

Listening to Their Heart: A Randomized Trial of Narrative Medicine

**Raya Elfadel Kheirbek** , Bonnie Marr, Daniel Herr, Univ of Maryland, Baltimore, MD

1:30 PM

Board # 3093

Non-vitamin K Antagonist Oral Anticoagulants versus Warfarin: Varying Outcomes Among Nonvalvular Atrial Fibrillation Patients With Multimorbidity

Steve Deitelzweig, Ochsner Clinic Fndn, New Orleans, LA; Allison Keshishian, STATinMED Res and New York City Coll of Technology, Ann Arbor, MI; Amiee Kang, Amol Dhamane, Bristol-Myers Squibb Company, Lawrenceville, NJ; Xuemei Luo, Pfizer, Inc., Groton, CT; **Christian Klem** , Bristol-Myers Squibb Company, Princeton, NJ; Lisa Rosenblatt, Bristol-Myers Squibb Company, Lawrenceville, NJ; Jack Mardekian, Pfizer, Inc., New York, NY; Jenny Jiang, Bristol-Myers Squibb Company, Lawrenceville, NJ; Huseyin Yuce, New York City Coll of Technology, New York, NY; Gregory Y.H. Lip, Liverpool Ctr for Cardiovascular Science, Univ of Liverpool and Liverpool Heart & Chest Hosp, Liverpool, United Kingdom

1:30 PM

Board # 3095

Myopathy and Rhabdomyolysis With Concomitant Use of Ticagrelor and High-intensity Statins in the Elderly

**Mohamed Mohamoud** , FDA, Silver Spring, MD; Daniel Woronow, Food and Drug Adminstration, Rockville, MD; Nicole Haug, Harvard Medical Sch, Boston, MA; Daniel Bak, Eileen Wu, Corinne Woods, Monica Munoz, Grace Chai, Danijela Stojanovic, FDA, Silver Spring, MD; Ting-Ying Huang, Harvard Medical Sch, Silver Spring, MD

1:30 PM

Board # 3098

Temporal Trends in the Prevalence and Outcomes of Geriatric Patients With Acute Myocardial Infarction in Japan -A Report From the Miyagi Ami Registry Study-

**Koichi Sato** , Tohoku Univ Graduate Sch of Med, Sendai, Japan; Jun Takahashi, Tohoku Univ Graduate Sch, Sendai, Japan; Kiyotaka Hao, Tohoku Univ Hosp, Sendai Miyagi, Japan; Satoshi Miyata, Yasuhiko Sakata, Tohoku Univ, Sendai, Japan; Hiroaki Shimokawa, Tohoku Univ, Sendai City, Japan

1:30 PM

Board # 3094

Frailty Assessment and Short-term Prognosis in Elderly Hospitalized Patients With Cardiovascular Disease

**Yaodan Liang** , Beijing Hosp, Beijing, China; Hua Wang, Beijing Hosp, beijing, China; Kefan Fu, Ning Sun, Simin Yao, Peipei Zheng, Yuhao Wan, Jiefu Yang, Beijing Hosp, Beijing, China

1:30 PM

Poster Professor

Joseph S Alpert, Tucson, AZ

# Abstract Poster Session

## CA.APS.07 - Cardiovascular Development, Rescue and Regeneration

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1115

Multi-Modal Imaging Investigation of Placenta-Heart-Brain Axis in an Genetically Engineered Mouse Model of Hypoplastic Left Heart Syndrome

**Yijen L Wu** , Tuan Tuan Tan, Univ of Pittsburgh, Pittsburgh, PA; George C Gabriel, Univ of Pittsburgh SOM, Pittsburgh, PA; Nathan Salamacha, Samuel Wyman, Univ of Pittsburgh, Pittsburgh, PA; Anthony G Christodoulou, Cedars-Sinai Medical Ctr, W Hollywood, CA; Cecilia W Lo, Univ of Pittsburgh, Pittsburgh, PA

1:30 PM

Board # 1116

Creg1 **is Required for Proper Myocardial Compaction**

**Russell J Pepe** , Yanmei Qi, Jie Liu, Pranav Sathuvalli, Billie Fyfe-Kirschner, He Wang, Leonard Y Lee, Shaohua Li, Rutgers Robert Wood Johnson Medical Sch, New Brunswick, NJ

1:30 PM

Board # 1117

Engineered Three-Dimensional Vascularized Cardiac Muscle Construct for Myocardial Repair and Regeneration

**Xi Lou** , Univ of Alabama at Birmingham, Birmingham, AL; Chengming Fan, Univ of Alabama at Birmingham, birmingham, AL; Jianyi Zhang, Mani T. Valarmathi, Univ of Alabama at Birmingham, Birmingham, AL

1:30 PM

Board # 1118

Platelet Derived Growth Factor-AB Improves Scar Mechanics and Vascularity After Myocardial Infarction

Sujitha Thavapalachandran, Westmead Inst for Medical Res, Sydney, Australia; Stuart M Grieve, Charles Perkins Ctr, Sydney, Australia; Thi Yl Le, Kalyan Raguram, Westmead Inst for Medical Res, Sydney, Australia; James E Hudson, QIMR Berghofer Medical Res Inst, Queensland, Australia; Jim Pouliopoulos, Westmead Hosp, Sydney, Australia; Gemma A Figtree, Kolling Inst of Medical Res, Sydney, Australia; Anthony M Barry, Paula Brown, Westmead Hosp, Sydney, Australia; Scott Kesteven, Victor Chang Cardiac Res Inst, Sydney, Australia; Richard J Mills, QIMR Berghofer Medical Res Inst, Queensland, Australia; Pramesh Kovoor, Liza Thomas, Alan R Denniss, Westmead Hosp, Sydney, Australia; Eddy Kizana, Westmead Inst for Medical Res, Sydney, Australia; Michael P Feneley, Robert M Graham, Richard P Harvey, Victor Chang Cardiac Res Inst, Sydney, Australia; **James Jh Chong** , Westmead Inst for Medical Res, Sydney, Australia

1:30 PM

Board # 1119

Therapeutic Efficacy of Large Aligned Cardiac Tissue Derived From Xenofree Induced Pluripotent Stem Cell in a Porcine Ischemic Cardiomyopathy Model

**Kota Suzuki** , Shigeru Miyagawa, Liu Li, Itsunari Minami, Junjun Li, Osaka Univ Graduate Sch of Med, Suita-city, Osaka, Japan; Takuji Kawamura, Osaka Univ Graduate Sch of Med, Suita-city, Osaka, Japan; Ai Kawamura, Akima Harada, Yoshiki Sawa, Osaka Univ Graduate Sch of Med, Suita-city, Osaka, Japan

1:30 PM

Board # 1120

Cardiac Stem-Cell Therapy in the Field: Under Regulated, Under Observed, Poorly Understood!

**Amanda Lindeman** , Univ of Florida, Gainesville, FL; Keith L March, VA Medical Ctr, Gainesville, FL; Carl J Pepine, Univ of Florida, Gainesville, FL

1:30 PM

Board # 1122

Cyanobacteria-alginate Microgels For Sustained Photosynthetic Oxygen Delivery To Rescue Cardiomyocytes In An Ischemic Milieu

**Lyndsay M Stapleton** , Stanford Univ, Palo Alto, CA; Justin M Farry, Haley J Lucian, Hanjay Wang, Kailey P Totherow, Stanford Univ, Stanford, CA; Michael J Paulsen, Stanford Univ, Los Altos, CA; Gillie Agmon, Stanford Univ, Palo Alto, CA; Mariana Cabatu, Stanford Univ, Palo Alto; Akshara D Thakore, Anahita N Eskandari, Shreya D Anilkumar, Frank J. Buncom IV, Eric A Appel, Y Joseph Y Woo, Stanford Univ, Stanford, CA

# Abstract Poster Session

## HF.APS.43 - Clinical Advances in Aortic Valve Disease

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Karim M Al-azizi, Springfield, MA

1:30 PM

Board # 2281

**Two Photon Excited Fluorescence Microscopy Metrics are Sensitive to Early Phenotypic Changes in Calcific Aortic Valve Disease** in vitro **and** ex vivo

**Ishita Tandon** , Olivia Kolenc, Shelby Johns, Delaney Cross, Alan Woessner, Isaac Vargas Lopez, Timothy Muldoon, Kyle Quinn, Kartik Balachandran, Univ of Arkansas, Fayetteville, AR

1:30 PM

Board # 2282

Predictors of Major Adverse Cardiac Events in Asymptomatic Low Gradient Severe Aortic Stenosis Stratified by Stroke Volume Index

**Waleed Al-Darzi** , Tamara Roumayah, Crystal Seudeal, Abigail Entz, Kristen Brooks, Edward Peterson, Karthikeyan Ananthasubramaniam, Henry Ford Hosp, Detroit, MI

1:30 PM

Board # 2283

Cardiovascular Adaptations in Chronic Mixed Aortic Valve Disease: Increase in Valve Gradients, but Little Left Ventricular Dilatation Over Time

**Nicolas Isaza** , Milind Y Desai, Samir R Kapadia, Amar Krishnaswamy, L. Leonardo Rodriguez, Richard A Grimm, Julijana Conic, Eric E Rosselli, Marc Gillinov, Douglas R Johnston, Lars G Svensson, Brian P Griffin, Zoran B Popović, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 2284

Effect of Aortic Valve Morphology on the Hemodynamic and Anatomic Progression of Aortic Stenosis

**Mylene Shen** , Quebec Heart and Lung Inst-Univ Laval, Quebec City, QC, Canada; Lionel Tastet, IUCPQ, Quebec, QC, Canada; Romain Capoulade, DR Grand Ouest Inserm, Nantes, France; Marie Arsenault, Elisabeth Bédard, Quebec Heart and Lung Inst, Quebec, QC, Canada; Marie Annick Clavel, Quebec Heart Inst, Quebec, QC, Canada; Philippe Pibarot, IUCPQ-UL, Quebec, QC, Canada

1:30 PM

Board # 2285

Serotonin Related Gene Expression Patterns in Aortic Valve Interstitial Cells Are Altered by Proliferation and Serotonin Transporter Inhibition

**Arbi Aghali** , Samuel J. Keeney, Emmett G. Fitzpatrick, Halley Shukla, Children's Hosp of Philadelphia, Philadelphia, PA; Estibaliz Castillero, Columbia Univ, New York, NY; Ilia Fishbein, The Children's Hosp of Philadelphia, Philadelphia, PA; Giovanni Ferrari, Columbia Univ, New York, NY; Robert J. Levy, Children's Hosp of Philadelphia, Philadelphia, PA

1:30 PM

Board # 2286

Healthcare and Health Disparities and Their Impact on Resource Utilization and Cost After Transcatheter Aortic Valve Replacement: A Nationwide Analysis of Real-world Data

Setri Fugar, Rush Univ Medical Ctr, Chicago, IL; **Alexis K Okoh** , RWJ Barnabas Health NBIMC, Newark, NJ; Swaiman Singh, Drexel Coll of Med, Philadelphia, PA; Aakash Garg, Icahn school of Med at Mount sinai/JJPVA medical center, Brooklyn, NY; Devangi Dave, RWJ Barnabas Health NBIMC, Newark, NJ; Chunguang Chen, Newark Beth Israel Med Ctr, Newark, NJ; Bruce Nicholas Haik, RWJ Barnabas Health, High Bridge, NJ; Marc Cohen, NBIMC, Newark, NJ; Leonard Lee, RWJ Barnabas Health, New Brunswick, NJ; Mark Russo, Columbia Univ, New York, NY

1:30 PM

Board # 2287

Does Vitamin D/Calcium Supplement Intake Worsen Aortic Stenosis Progression?

Antonette Karrthik, Keerat Rai Ahuja, Mohamed M Gad, Cleveland Clinic, Cleveland, OH; **Najdat Bazarbashi** , Univ of Maryland, Baltimore, MD; Manpreet Kaur, Patrick Collier, Milind Desai, Brian P. Griffin, Samir Kapadia, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 2288

Deletion of Endothelial Integrin Linked Kinase (ILK) Accelerates the Development of Calcific Aortic Valve Disease

Paula Reventun, Sandra Sanchez-Esteban, Univ Alcala, Alcala De Henares Madrid, Spain; Mercedes Castro, Hosp Ramon y Cajal, Madrid, Spain; Cristina Ruiz, Univ Alcala, Alcala De Henares Madrid, Spain; Ignacio Hernandez Navarro, Univ Francisco de Vitoria, Pozuelo de Alarcon. Madrid, Spain; Jose Lopez-Menendez, Hosp Ramon y Cajal, Madrid, Spain; Carlos Zaragoza, Univ Francisco de Vitoria, Pozuelo de Alarcon Madrid, Spain; **Marta Saura** , Univ Alcala, Alcala De Henares Madrid, Spain

1:30 PM

Board # 2289

Impaired Hyperemic Myocardial Blood Flow is Associated With Subclinical Systolic Dysfunction and Myocardial Injury in Aortic Stenosis

**Wunan Zhou** , Yee-Ping Sun, Sanjay Divakaran, Alvin Chandra, Brigham and Women's Hosp, Boston, MA; Navkaranbir S Bajaj, UAB, Birmingham, AL; Leanne Barrett, Laurel Campbell, Bibbo Courtney, Jon Hainer, Brigham and Women's Hosp, Boston, MA; Eldrin F Lewis, Brigham Womens Hosp, Boston, MA; Viviany Taqueti, Brigham and Women's Hosp, Boston, MA; Sharmila Dorbala, Brigham and Womens, Boston, MA; Ron Blankstein, Pinak B Shah, Brigham and Womens Hosp, Boston, MA; Tsuyoshi Kaneko, Brigham and Women's Hosp, Boston, MA; Dale Adler, Brigham Women's Hosp, Boston, MA; Patrick O'Gara, Brigham and Women's Hosp, Boston, MA; Marcelo F Di Carli, Brigham and Womens Hosp, Boston, MA

1:30 PM

Board # 2290

Prevalence and Risk Factors for Silent Brain Infarction in Patients With Severe Aortic Stenosis

**Soichiro Tamura** , Shinichi Iwata, Asahiro Ito, Kim Andrew T, Yu Kawai, Shinichi Nonin, Sera Ishikawa, Yasuhiro Izumiya, Toshihiko Shibata, Minoru Yoshiyama, Osaka City Univ, Osaka, Japan

1:30 PM

Board # 2291

CACNA1C Promotes Development of Calcific Aortic Valve Disease Through Dystrophic and Osteo/Chondrogenic Pathways

**Maiko Matsui** , Mara Storto, Yasin Hussain, Andrew Mark Gregg, Geoffrey Pitt, Weill Cornell Medical Coll, New York, NY

# Abstract Poster Session

## EP.APS.30 - Development of Cardiovascular Disease Across the Lifetime

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3071

High Concordance of Non-ideal Cardiovascular Health Metrics in a Nation-wide Study of 5,364 Spouse-pairs

**Dov Shiffman** , Judy Z Louie, James J Devlin, Charles M Rowland, Quest Diagnostics, San Juan Capistrano, CA; Samia Mora, Brigham and Women's Hosp, Boston, MA

1:30 PM

Board # 3072

Maternal Dietary Patterns During Pregnancy Predict Early Childhood Growth Trajectories and Obesity Risk

**Zunsong Hu** , Frances A Tylavsky, Mehmet Kocak, Jay H Fowke, Joan C Han, Robert L Davis, Univ of Tennessee Health Science Ctr, Memphis, TN; Kaja Z LeWinn, Nicole R Bush, Univ of California San Francisco, San Francisco, CA; Sheela Sathyanarayana, Seattle Children's Res Inst, Seattle, WA; Catherine J Karr, Univ of Washington, Seattle, WA; Qi Zhao, Univ of Tennessee Health Science Ctr, Memphis, TN

1:30 PM

Board # 3073

Familial Aggregation of Ideal Cardiovascular Health and Cardiovascular Disease Disability-adjusted Life Years in Parent-offspring Dyads: Analysis of the Framingham Heart Study

**James Muchira** , Vanderbilt Univ, Nashville, TN; Philimon Gona, Suzanne Leveille, Laura L Hayman, Univ of Massachusetts Boston, Boston, MA

1:30 PM

Board # 3074

Age-varying Effects of Risk Factors on Cardiovascular Disease and Mortality: A Nationwide Cohort Study

Hokyou Lee, Yonsei Univ, Seoul, Korea, Republic of; **Norrina B Allen** , Donald M Lloyd-Jones, Northwestern Univ, Chicago, IL; So Mi Jemma Cho, Yonsei Univ, Seoul; Hyeon Chang Kim, Yonsei Univ, Seoul, Korea, Republic of

1:30 PM

Board # 3075

Association of Childhood Sleep Apnea With Adolescent Hypertension: The Penn State Child Cohort

**Edward Bixler** , Fan He, Julio Fernandez-Mendoza, Liao Duanping, Susan Calhoun, Alexandros Vgontzas, Penn State Univ, Hershey, PA

1:30 PM

Board # 3076

Impact of Excessive Birth Weight on Body Mass Index Growth Trajectories Over the Life Course: The Bogalusa Heart Study

**Yajun Guo** , Tulane Univ, New Orleans, LA; Camilo Fernandez, HeartGEN Inst, Boston, MA; Alexander Razavi, Tulane Univ, New Orleans, LA; Rupert Barshop, Tulane, New Orleans, LA; Lydia A Bazzano, Tulane Univ SPH&TM, New Orleans, LA

1:30 PM

Board # 3077

The Longitudinal Changes in Cardiovascular Biomarkers in Community Dwellers: The Tohoku Medical Megabank Project

**Yuka Kotozaki** , Iwate Medical Univ, Yahaba, Japan; Kozo Tanno, Iwate Medical Univ, Morioka, Japan; Koichi Asahi, Takahito Nasu, Hideki Ohmomo, Ryo Otomo, Iwate Medical Univ, Yahaba, Japan; Fumitaka Tanaka, Iwate Medical Univ, Morioka, Japan; Atsushi Shimizu, Iwate Medical Univ, Yahaba, Japan; Kiyomi Sakata, Iwate Medical Univ Sch Med, Morioka, Japan; Makoto Sasaki, Mamoru Satoh, Iwate Medical Univ, Yahaba, Japan

1:30 PM

Board # 3078

Pediatric Mass Screening (Kagawa Pediatric Preventive Checkup) and Gene Screening are Useful for Early Diagnosis of Familial Hypercholesterolemia

**Shohei Ishikawa** , Takuma Sakamoto, Genki Kurashita, Takahiro Izumi, Tomoko Inoue, Eriko Nasu, Atsushi Tobiume, Shota Yokoyama, Hideyuki Hamaya, Keiji Matsunaga, Ryo Kawakami, Yuichi Miyake, Makoto Ishizawa, Kaori Ishikawa, Kazushi Murakami, Takahisa Noma, Tetsuo Minamino, Faculty of Med Kagawa Univ, Kagawa, Japan

1:30 PM

Board # 3079

Life Course Determinants of Adult Diastolic Function: Insights From the Bogalusa Heart Study

**Camilo Fernandez** , HeartGEN Inst, Boston, MA; Alexander Razavi, Tulane Univ, New Orleans, LA; Rupert Barshop, Tulane, New Orleans, LA; Yajun Guo, Tulane Univ, New Orleans, LA; Lydia A Bazzano, Tulane Univ SPH&TM, New Orleans, LA

1:30 PM

Board # 3080

Cardiovascular Health Decline in Adolescent Girls

**Holly C Gooding** , Emory Univ Sch of Med, Atlanta, GA; Hongyan Ning, Amanda Marma Perak, Norrina B Allen, Northwestern Univ, Chicago, IL; Martha Singer, Boston Univ Sch of Medicin, Boston, MA; Donald M Lloyd-Jones, Northwestern Univ, Chicago, IL; Sarah D De Ferranti, Boston Children's Hosp, Boston, MA

1:30 PM

Poster Professor

Tene T Lewis, Atlanta, GA

# Abstract Poster Session

## AT.APS.24 - Endothelial Function and Vascular Disease

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1050

Dietary Nitrate Supplementation With Clopidogrel Therapy in Stable Coronary Artery Disease Patients

**Fairoz B Abdul** , Birmingham City Hosp, Birmingham, United Kingdom; Tim Kinnaird, Univ Hosp of Wales, Cardiff, United Kingdom; Phillip James, Cardiff Metropolitian Univ, Cardiff, United Kingdom; Richard Anderson, Univ Hosp of Wales, Cardiff

1:30 PM

Board # 1052

Hypercholesterolemia May Augment the Progression of Endothelial Dysfunction in Hypertension: Multicenter Prospective Study FMD-J Study

**Chisa Matsumoto** , Hirofumi Tomiyama, Akira Yamashina, Taishiro Chikamori, Tokyo Medical Univ, Tokyo, Japan; FMD-J Study Group

1:30 PM

Board # 1053

C1q/tnf-related Protein5 (ctrp5) as a Novel Molecule Contributing to Diabetic Vascular Endothelium Dysfunction Through Suppressing Rhoa/rock Signaling

**Yajing Wang** , Jing Liu, Gan Lu, Demin Liu, Ling Zhang, Devin Kolmetzky, Bernard Lopez, Theodore Christopher, Xin L Ma, Thomas Jefferson Univ, Philadelphia, PA

1:30 PM

Board # 1055

Nogo-B Regulates Mitochondria Associated Membrane Remodeling in Hyperglycemia Induced Endothelium Dysfunction

**Cheng Zhang** , Yaru Cui, Dan Shan, Telushi Ajdora, Chao Zhong, Jun Yu, Temple Univ, Philadelphia, PA

1:30 PM

Board # 1057

Salt-Sensitive Hypertension is Blunted by Deletion of G Protein-Coupled Receptor 35 Gene in Mice

**Hainan Li** , Megan M O'Meara, Sai Pranathi Meda Venkata, Jie-mei Wang, Wayne State Univ, Detroit, MI

1:30 PM

Poster Professor

Changcheng Zhou, Lexington, KY

1:30 PM

Board # 1060

Discordance Between Blood Pressure and Endothelial Function Measurements; is it Time to Look Beyond Blood Pressure for Early Detection of CVD Risk?

Yasamin Naghavi, Univ of Houston, Houston, TX; Albert Yen, Endothelix, Houston, TX; Stanley Kleis, Univ of Houston, Houston, TX; Hirofumi Tanaka, Univ of Texas Austin, Austin, TX; **Morteza Naghavi** , SHAPE, Palo Alto, CA; Ahmed Gul 77056, Ralph Metcalfe, Univ of Houston, HOUSTON, TX

1:30 PM

Board # 1061

Association of Extremely High Levels of High-Density Lipoprotein Cholesterol With Endothelial Dysfunction in Men

**Yuji Takaeko** , Hiroshima Univ, Hiroshima, Japan; Shogo Matsui, Hiroshima Univ Graduate Sch of Biomedical Sciences, Hiroshima, Japan; Masato Kajikawa, Hiroshima Univ, Hiroshima, Japan; Tatsuya Maruhashi, Hiroshima Univ, Hiroshima Japan, Japan; Shinji Kishimoto, Hiroshima Univ, Hiroshima Japan, Japan, Hiroshima, Japan; Haruki Hashimoto, Hiroshima City Hosp, Hiroshima City, Japan; Yukihito Higashi, Hiroshima Univ, Hiroshima, Japan

1:30 PM

Board # 1062

Psoriasis Promotes Endothelial Inflammation and Dysfunction

**Michael Tawil** , Michael S Garshick, New York Univ Medical Ctr, New York, NY; Tessa Barrett, NYU Sch of Med, New York, NY; Jose Scher, Andrea Neimann, New York Univ Medical Ctr, New York, NY; Sanja Jelic, Columbia Univ, New York, NY; Edward A Fisher, NYU Langone Medical Ctr, New York, NY; James Krueger, Rockefeller Univ, New York, NY; Jeffrey S Berger, New York Univ Sch Med, New York, NY

# Abstract Poster Session

## EA.APS.38 - Factors Impacting Outcomes in AF Ablation

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2162

Catheter Ablation for Long Standing Persistent Atrial Fibrillation in Patients Who Sustain Sinus Rhythm After Electrical Cardioversion

**Takahiro Hayashi** , Masato Murakami, Yuka Mashimo, Takashi Nishimoto, Shingo Mizuno, Shonan Kamakura General Hosp, Kamakura, Japan; Hirokazu Miyashita, Shonan Kamakura General Hosp Stroke Ctr, Kamakura, Japan; Noriaki Moriyama, Natl Cerebral and Cardiovascular Ct, Suita, Osaka, Japan; Hiroaki Yokoyama, Kazuki Tobita, Koki Shishido, Futoshi Yamanaka, Yutaka Tanaka, Saeko Takahashi, Shigeru Saito, Shonan Kamakura General Hosp, Kamakura, Japan

1:30 PM

Board # 2163

Difference in the Mechanism of Early and Late Phase Recurrent Atrial Fibrillation Following Catheter Ablation Procedure: Its Relation to the Subsequent Clinical Outcome

**Hisanori Kanazawa** , Miwa Ito, Yusuke Kanemaru, Takuya Kiyama, Yusei Kawahara, Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

1:30 PM

Board # 2164

Is Incomplete Left Atrial Posterior Wall Isolation Associated With Recurrence of Atrial Fibrillation After Radiofrequency Catheter Ablation?

**Takefumi Fujito** , Naoyuki Kamiyama, Atsushi Mochizuki, Daigo Nagahara, Tetsuji Miura, Sapporo Medical Univ, Sapporo, Japan

1:30 PM

Board # 2165

Stroke Risk in Paroxysmal and Persistent Atrial Fibrillation Treated With Anti-arrhythmic Drugs vs Catheter Ablation

**Sanghamitra Mohanty** , Chintan G Trivedi, Domenico Giovanni Della Rocca, Carola Gianni, Mohammed Bassiouny, Ugur Canpolat, Bryan MacDonald, John David Burkhardt, Javier Sanchez, Texas Cardiac Arrhythmia Inst, Austin, TX; Patrick M Hranitzky, Texas Cardiac Arrhythmia Inst, Hillsborough, NC; Joe Gallinghouse, Amin Al-ahmad, Rodney Paul Horton, Texas Cardiac Arrhythmia Inst, Austin, TX; Luigi Di Biase, 400 Central Park West Apt 9G, New York, NY; Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

1:30 PM

Board # 2166

Cryoballoon Time-to-Effect Dosing is Insufficient to Predict Permanent Pulmonary Vein Isolation

**Emrie Tomaiko** , Carla Lockhart, Jonathan Ko, Banner Univ Medical Ctr, Phoenix, AZ; Wilber Su, Banner Univ Medical Ctr, Paradise Vly, AZ

1:30 PM

Board # 2167

Predictors of Minimal Clinically Important Difference of Quality of Life and Severity Score Post Atrial Fibrillation Ablation

**Zahra Azizi** , Southlake Regional Health Ctr, Aurora, ON, Canada; Vidal Essebag, McGill Univ Health Ctr, Montreal, QC, Canada; Pouria Alipour, Southlake Regional Health Ctr, Newmarket, ON, Canada; Yaariv Khaykin, Southlake Regional Health Ctr, Richmond Hill, ON, Canada; Peter Leong-Sit, Schulich Sch of Med & Dentistry, London, ON, Canada; Jean-Francois Sarrazin, Univ Laval, Quebec, QC, Canada; Marcio Sturmer, Hôpital du Sacré-Coeur de Montreal, Montréal, ON, Canada; Carlos A Morillo, Alberta Health Services, Calgary, AB, Canada; Maria Terricabras, Southlake Regional Health Ctr, Aurora, ON, Canada; Guy Amit, McMaster Univ, Hamilton, ON, Canada; Jean-Francois Roux, Univ of Sherbrook, Sherbrooke, QC, Canada; Atul Verma, Southlake Regional Health Ctr, Newmarket, ON, Canada

1:30 PM

Board # 2168

Catheter Ablation of Atrial Fibrillation: A Network Meta-Analysis of Radiofrequency and Balloon-Based Technologies

**Babikir Kheiri** , Oregon Health & Science Univ, Portland, OR; Mohammed Osman, Univ of West Virgina, Grandblanc, MI; Khidir Dalouk, Oregon Health & Science Univ, Portland, OR; Eric Stecker, Knight Cardiovascular Inst, Portland, OR

1:30 PM

Board # 2169

The Effect of Elevated Body Mass Index on Atrial Fibrillation Recurrence After Ablation: A Systematic Review and Meta-Analysis

**Pablo Paz** , Texas Tech Univ Health Sciences Ctr, Lubbock, TX; Wasawat Vutthikraivit, Texas Tech Health Sciences Ctr, Lubbock, TX; Mohamed Elmassry, Texas Tech Univ Health S C, Lubbock, TX; Rubayat Rahman, Saif El Nawaa, Texas Tech Health Sciences Ctr, Lubbock, TX; Barbara Mantilla, Texas Tech Univ Health Science Ctr, Lubbock, TX; Pattara Rattanawong, Univ of Hawaii, Honolulu, HI; Prapaipan Putthapiban, Einstein Medical Ctr, Philadelphia, PA; Mohamed Zitun, Texas Tech Univ HSC, Lubbock, TX; Mohammad Ansari, Texas Tech Univ Health Science Ctr, Lubbock, TX; Scott W Shurmur, TEXAS TECH UNIV, Lubbock, TX

1:30 PM

Board # 2170

General Anesthesia Reduces Pulmonary Veins Reconnection in Patients Undergoing Atrial Fibrillation Ablation: Systematic Review and Meta-Analysis

**Jalaj Garg** , Mohit Turagam, Syeda Atiqa Batul, Poojita Shivamurthy, Manaswi Bhupesh Pathik, Kenji Kuroki, Aamir A Sofi, Georgios Syros, Marie-Noelle Langan, Jacob Sam Koruth, Marc Miller, Anthony Gomes, Subbarao Choudry, William Whang, Srinivas Dukkipati, Vivek Y Reddy, Icahn Sch of Med at Mount Sinai Medical Ctr, New York, NY

1:30 PM

Board # 2171

Impact of Alcohol Intake on Outcomes of Atrial Fibrillation Catheter Ablation: A Propensity Score Matched Comparison

**Domenico Giovanni Della Rocca** , St. David's Medical Ctr, Austin, TX; Chintan Gautambhai Trivedi, TCAI, Austin, TX; Luigi Di Biase Sr., Albert Einstein Coll of Med, New York, NY; Sanghamitra Mohanty, St.Davids Medical Ctr, Austin, TX; Veronica Natale, TCAI, Austin, TX; Jorge Romero, Montefiore Albert Einstein, Bronx, NY; Mohamed Ahmed Bassiouny, Cleveland Clinic Fndn, Cleveland, OH; Carola Gianni, Texas Cardiac Arrhythmia Inst, Austin, TX; Bryan MacDonald, TCAI, Austin, TX; Amin Al-ahmad, Texas Cardiac Arrhythmia Inst, Austin, TX; Joe Gallinghouse, David Burkhardt, Rodney Paul Horton, TCAI, Austin, TX; Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

# Abstract Poster Session

## GE.APS.04 - Functional Studies of Cardiovascular Disease

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1137

Upregulation Cardiac Beta3-Adrenergic Receptor-Activated Inducible Nitric Oxide Synthase Uncoupling Promotes Cardiac Aging

Che Ping Cheng, Peng Zhou, Zhe Chen, Xiaowei Zhang, **Xiaoqiang Sun** , Dalane Kitzman, Michael Callahan, Heng-Jie Cheng, Wake Forest Sch of Med, Winston-Salem, NC

1:30 PM

Board # 1138

**The Role and Mechanism of Chronic Ca** 2+ **/Calmodulin-Dependent Protein Kinase II Inhibition in a Mouse Model of Diabetic Cardiomyopathy**

**Heng-Jie Cheng** , Yixi Liu, Xiaoqiang Sun, Jen-Jar Lin, Alexei V Mikhailov, David Zhao, Dalane Kitzman, Che Ping Cheng, Wake Forest Sch of Med, Winston-Salem, NC

1:30 PM

Board # 1139

Cathepsin D Mediates the Osteogenic and Fibrocalcific Responses to Soluble Matrilin-2 in Human Avics Through the Erk1/2 Pathway

**Qingzhou Yao** , Balachandar Nedumaran, Peng Zhao, Lihua Ao, David A Fullerton, Xianzhong Meng, Univ of Colorado, Aurora, CO

1:30 PM

Board # 1140

Transcriptomics of Lung Molecular Remodeling in Pulmonary Hypertension Due to Left Heart Disease: Benefits of Combined PBI-4050/Valsartan Therapy

**Julie Hussin** , Montreal Heart Inst, Montréal, QC, Canada; Quang Nguyen, Montreal Heart Inst, Montreal, QC, Canada; Mohamed Jalloul Nsaibia, Prometic Biosciences Inc., Laval, QC, Canada; Jean-Christophe Grenier, Axel Seguin, Montreal Heart Inst, Montréal, QC, Canada; Jean-Claude Tardif, Yanfen Shi, Martin G Sirois, Montreal Heart Inst, Montreal, QC, Canada; Brigitte Grouix, Prometic Biosciences Inc., Laval, QC, Canada; Lyne Gagnon, Prometic Biosciences Inc, Laval, QC, Canada; Jocelyn Dupuis, Montreal Heart Inst, Montreal, QC, Canada

1:30 PM

Board # 1141

Atrial Fibrillation is Associated With Atrial Amyloid and Elevated Atrial Natriuretic Peptide Precursor Proteins

**Patrick D Smith** , Beth S Lovano, Lauren Gillinov, Robert Borden, Kurt Niebauer, Qingyu Wu, David R Van Wagoner, Mina K Chung, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 1142

Tea Domain Family Member 1 (TEAD1) Regulates IGF1 and mTOR Pathway in the Heart

**Rajaganapathi Jagannathan** , Jeongkyung Lee, Ruya Liu, Ping Yang, Feng Li, Vinny Negi, Vijay Yechoor, Mousumi Moulik, Univ of Pittsburgh, Pittsburgh, PA

1:30 PM

Board # 1143

Kynurenine And Spermidine Are Associated With Reduced Skeletal Muscle Function, Expression Of PPARa And Elevated Depression Score In Patients With Heart Failure

**Tarek Bekfani** , Sophie Neugebauer, Mohamed Bekhite ELsaied, Steffen Derlien, Jenny Nisser, Ali Hamadanchi, Marion S. Hilse, Michael Kiehntopf, Ulrich C. Smolenski, Gabriele Lehmann, Gunter Wolf, Sven Moebius-Winkler, P. Christian Schulze, Univ Hosp Jena, Jena, Germany

1:30 PM

Board # 1144

Proteomic and Functional Analysis Reveals Distinct Effect of Rap1A GTPase Deficiency on C57BL/6 Mouse Heart

Sadaf Saleem Uddin, Faisal Khan, Intl Cntr for Chem Bio Sci, Karachi, Pakistan; Lawrence A. Quilliam, Indiana Univ Sch of Med, Indianapolis, IN; Syed Ghulam Musharraf, **Maqsood A Chotani** , Intl Cntr for Chem Bio Sci, Karachi, Pakistan

1:30 PM

Board # 1145

Kinome Screen in Human Hepatocytes Identifies TRRAP as Regulator of Triglyceride Metabolism

**Deepti Abbey** , Christopher Rainville, Susannah Elwyn, Donna M Conlon, Amrith Rodrigues, Jeffrey Billheimer, David C Schultz, Nicholas J Hand, Daniel J Rader, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 1146

Exosomal RNAS as Potential Biomarkers of Cardiovascular Risk in NASA Astronauts

David Goukassian, Icahn Sch of Med at Mount Sinai, Philadelphia, PA; May Truongcao, Temple Univ, Philadelphia, PA; Arsen Arakelyan, NAS RA,, Yerevan, Armenia; Paul Mills, UCSD, La Jolla, CA; Ken Walsh, Univ of Virgina, Charlottesville, VA; Sankar Addya, Thomas Jefferson Univ, Philadelphia, PA; Angela Evans, UC DAVIS, Livermore, CA; Mathew Coleman, UC Davis, Livermore, CA; Kenneth Fish, Mount Sinai Sch of Med, New York, NY; Roger Joseph Hajjar, Mount Sinai Cardiovascular Res, New York, NY; Raj Kishore, **Venkata N s Garikipati** , Temple Univ Sch of Med, Philadelphia, PA

1:30 PM

Board # 1147

Plasma Extracellular Vesicles MicroRNAs Serve as Potential Mediators for Atherosclerotic Cardiovascular Disease in HIV Patients

**Andrea da Fonseca Ferreira** , Chunming Dong, Conrad Macon, Lukun Zhang, Jian Qin Wei, Bernard Degnan, Derek Dykxhoorn, Univ of Miami, Miami, FL; Dushyantha Jayaweera, Univ of Miami, Miami, United States Minor Outlying Islands; Liyong Wang, Univ of Miami, Miami, FL

1:30 PM

Board # 1148

Circulating MicroRNA-454-3p is Associated With Acute Kidney Injury in Patients With Acute Decompensated Heart Failure

**Evelyn M Templeton** , Moritz Lasse, Anna P Pilbrow, Vicky A Cameron, John W Pickering, Univ of Otago Christchurch, Christchurch, New Zealand; Daniel Hertzberg, Karolinska Instt, Stockholm, Sweden; Chris M Frampton, Univ of Otago Christchurch, Christchurch, New Zealand; Zoltan H Endre, Prince of Wales Hosp and Clinical Sch, Sydney, Australia; Arthur Mark Richards, Natl Univ of Singapore, Singapore, Singapore; Robert N Doughty, Univ of Auckland, Auckland, New Zealand; Richard W Troughton, Univ of Otago Christchurch, Christchurch, New Zealand

1:30 PM

Board # 1149

De Novo Onset of Atrial Fibrillation in Heart Failure Patients is Predicted by the Blood Transcriptome

**Marja Steenman** , l'Inst du Thorax, Nantes, France; Guillaume Lamirault, l'Inst du Thorax, Saint Herblain, France; Catherine Chevalier, Isabelle Guisle, Beatrice Guyomarch, l'Inst du Thorax, Nantes, France; Imen Fellah Hebia, Aude Solnon, l'Inst du Thorax, Saint Herblain, France; Jean Baptiste Gourraud, l'Inst du Thorax, Nantes, France; Laurent Desprets, Selim Abbey, l'Inst du Thorax, Saint Herblain, France; Christophe Leclercq, CHU Rennes, Rennes, France; Paul Bru, Antoine Milhem, CH La Rochelle, La Rochelle, France; Olivier Billon, CHD Vendée, La Roche Sur Yon, France; Fréderic Anselme, Arnaud Savouré, CHU Rouen, Rouen, France; Jean Noel Trochu, l'Inst du Thorax, Saint Herblain, France; Rémi Houlgatte, INSERM U1256, Nancy, France; Gilles Lande, l'Inst du Thorax, Saint Herblain, France

# Abstract Poster Session

## QU.APS.07 - Health Care Costs, Quality of Life and Value

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3162

Cost-Effectiveness Analysis of Adult Patients Receiving Extracorporeal Membrane Oxygenation - Taiwan's Experiences

**Jou Wei Lin** , Natl Taiwan Univ Hosp, Douliu City, Taiwan; Hsi-Yu Yu, Yih-Sharng Chen, Natl Taiwan Univ Hosp, Taipei, Taiwan

1:30 PM

Board # 3163

Cost-Effectiveness Analysis of Implantable Cardiac Devices in Patients With Systolic Heart Failure: A US Perspective Using Real World Data

**Xiaoxiao Lu** , Medtronic, Mounds View, MN; Victoria Federico Paly, Dhvani Shah, ICON Plc, New York, NY; Stelios Tsintzos, Medtronic Int Trading Sarl, Tolocheanz, Switzerland

1:30 PM

Board # 3164

Copayment Reduction Voucher Use and Impact on Medication Persistence and Clinical Outcomes: Lessons From the Artemis Randomized Clinical Trial

**Alexander Craig Fanaroff** , Univ of Pennsylvania, Philadelphia, PA; Eric D Peterson, Duke Clinical Res Inst, Chapel Hill, NC; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; Timothy D Henry, Cedars Sinai Medical Ctr, Cincinnati, OH; Christopher P Cannon, Baim Inst forClinical Res, Boston, MA; David J Cohen, Baim Inst forClinical Res, Boston, MA, Kansas City, MO; Niteesh Kumar Choudhry, Brigham and Women's Hosp, Boston, MA; Narinder P Bhalla, Brigham and Women's Hosp, Boston, MA, Chadds Ford, PA; James Michael Eudicone, Bristol-Myers Squibb, Princeton, NJ; Nipun Atreja, Astrazeneca, Wilmington, DE; Naeem Khan, AstraZeneca, Wilmington, DE; Tracy Y Wang, DCRI, Durham, NC

1:30 PM

Board # 3165

Insurance Type is Associated With Health-related Quality of Life in Heart Failure

**Favel L Mondesir** , Univ of Utah, Salt Lake City, UT; April Mohanty, Univ of Utah Sch of Med, Salt Lake City, UT; Jennifer Hong, Rachel Hess, Mingyuan Zhang, Tom Greene, Univ of Utah, Salt Lake City, UT; Benjamin A Steinberg, Univ of Utah, Sandy, UT; Jose Nativi-Nicolau, Univ of Utah, Salt Lake City, UT; Stavros G Drakos, Univ of Utah, Salt Lake Cty, UT; James C Fang, Univ of Utah Cardiology, Salt Lake City, UT; Peter Wohlfahrt, Joshua Biber, Omar Wever-Pinzon, Craig Selzman, Univ of Utah, Salt Lake City, UT; John Spertus, Mid America Heart Inst, Kansas City, MO; Josef Stehlik, Univ of Utah, Salt Lake City, UT

1:30 PM

Board # 3166

Understanding the Costs Associated With Cardiac Ablations

**Megan K Kawasaki** , David J Cleary, Daniel D Correa de Sa, Univ of Vermont Larner Coll of Med, Burlington, VT; Susan R Calame, Univ of Vermont Medical Ctr, Burlington, VT; Christopher M Dillon, Univ of Vermont Health Network, Burlington, VT; Mitchell H Tsai, Univ of Vermont Larner Coll of Med, Burlington, VT

1:30 PM

Board # 3167

Comparisons of Effectiveness, Safety, and Costs Among Oral Anticoagulant-treated Nonvalvular Atrial Fibrillation Patients With and Without Major Gastrointestinal Bleeding

Steve Deitelzweig, Ochsner Clinic Fndn, New Orleans, LA; Allison Keshishian, STATinMED Res and New York City Coll of Technology, Ann Arbor, MI; **Amiee Kang** , Amol Dhamane, Bristol-Myers Squibb Company, Lawrenceville, NJ; Xuemei Luo, Pfizer, Inc., Groton, CT; Neeraja Balachander, Bristol-Myers Squibb Company, Lawrenceville, NJ; Lisa Rosenblatt, Bristol-Myers Squibb, Lawrenceville, NJ; Jack Mardekian, Pfizer, Inc., New York, NY; Jenny Jiang, Bristol-Myers Squibb Company, Lawrenceville, NJ; Huseyin Yuce, New York City Coll of Technology, Brooklyn, NY; Gregory Y.H. Lip, Liverpool Ctr for Cardiovascular Science, Univ of Liverpool and Liverpool Heart & Chest Hosp, Liverpool, United Kingdom

1:30 PM

Board # 3168

Factors Related to Treatment Satisfaction After Left Ventricular Assist Device Implantation: Findings From The Mechanical Circulatory Support Measures of Adjustment and Quality of Life Study

Elizabeth A Hahn, Katy Wortman, Clyde W Yancy Jr., Northwestern Univ, Chicago, IL; Larry A Allen, Univ Colorado Denver, Aurora, CO; Colleen K McIlvennan, Univ of Colorado, Denver, CO; Quin E Denfeld, Oregon Health Science Univ, Portland, OR; Mary N Walsh, St. Vincent Heart Ctr, Indianapolis, IN; David Cella, Northwestern Univ, Chicago, IL; Joann Lindenfeld, Vanderbilt Univ, Nashville, TN; Bernice Ruo, Univ of California San Diego, La Jolla, CA; David Beiser, Univ Chicago, Chicago, IL; Catherine M Murks, Univ Chicago Hosp, Munster, IN; Dipanjan Banerjee, The Queen's Heart Physician Practice, Honolulu, HI; Jonathan Rich, Northwestern Univ, Skokie, IL; Sarah Buono, **Kathleen L Grady** , Northwestern Univ, Chicago, IL

1:30 PM

Board # 3169

Health Care Spending and Use of Coronary Revascularization Procedures Among VA-Medicare Advantage Dual-Enrolled Veterans

**Elias J Dayoub** , Univ of Pennsylvania, Philadelphia, PA; Elina L Medvedeva, Corporal Michael J. Crescenz VA Medical Ctr, Philadelphia, PA; Ashwin Nathan, Univ of Pennsylvania, Philadelphia, PA; Sameed Ahmed M Khatana, Hosp of the Univ of PA, Philadelphia, PA; Andrew J Epstein, Corporal Michael J. Crescenz VA Medical Ctr, Philadelphia, PA; Peter Groeneveld, Univ of Pennsylvania, Philadelphia, PA

# Abstract Poster Session

## AT.APS.21 - Hemostasis, Thrombosis and Fibrinolysis

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1063

Repeated Social Defeat Exaggerates Fibrin-rich Clot Formation in Fecl3-induced Arterial Thrombosis Mice Model by Enhancing NETs Formation

**Takeshi Sugimoto** , Kyoto Prefectural Univ of Med, Kyoto, Japan; Hiroyuki Yamada, Kyoto Prefectural Univ. of Med, Kyoto, Japan; Hiroshi Kubota, Daisuke Miyawaki, Kyoto Prefectural Univ of Med, Kyoto, Japan; Makoto Saburi, Kyoto Prefectural Univ of Med, Kyoto City, Japan; Noriyuki Wakana, Satoaki Matoba, Kyoto Prefectural Univ of Med, Kyoto, Japan

1:30 PM

Board # 1064

Sulfonated Peptidomimetics Are New Selective, Reversible, and Non-active Site Inhibitors of Human Coagulation Factor Xla

**Rami A Al-Horani** , Elnaz Parsaeian, Xavier Univ of Louisiana, New Orleans, LA

1:30 PM

Board # 1065

Structural Mechanism for the Mechanical Rupture of Fibrin Blood Clots

**Valerie Tutwiler** , Univ of Pennsylvania, Philadelphia, PA; Farkhad Maksudov, Rustem Litvinov, Univ of Massachusetts Lowell, Lowell, MA; Valeri Barsegov, John W Weisel, Philadelphia, PA

1:30 PM

Board # 1066

Triple Therapy is Associated With a Lower Risk of Stroke in Patients With Left Ventricular Thrombus: A Single Center Retrospective Study

**Aditya Sahai** , Jamal Mahar, Cleveland Clinic Fndn, Cleveland, OH; Haitham Ahmed, Advantage Care Physicians, Brooklyn, NY; Venugopal Menon, Robert Burton, Serge Harb, Cleveland Clinic Fndn, Cleveland, OH

1:30 PM

Board # 1068

The "Thrombosis-Bleeding Paradox" of Mechanical Circulatory Support: Shear Stress Promotes Platelet Prothrombosis and Microparticle Generation While Inducing Integrin αIIbβ3 Shedding and Decreased Aggregability

**Yana Roka-Moiia** , Daniel E. Palomares, Univ of Arizona, Tucson, AZ; Joseph E Italiano Jr., Harvard Medical Sch, Boston, MA; Jawaad Sheriff, Danny Bluestein, Stony Brook Univ, Stony Brook, NY; Marvin Slepian, Univ of Arizona, Tucson, AZ

1:30 PM

Board # 1069

Fibrinolytic Deficit and Risk of Death After Acute Pulmonary Embolism

**Yevgeniy Brailovsky** , Loyola Univ Medical Ctr, Maywood, IL; Vladimir Lakhter, Massachusetts General Hosp, Boston, MA; Carlos F Bechara, Emily Bontekoe, Debra Hoppensteadt, John J Lopez, Fakiha Siddiqui, Verghese Mathew, Bruce Lewis, Omer Iqbal, Jawed Fareed, Loyola Univ Medical Ctr, Maywood, IL; Amir Darki, Loyola Univ Medical Ctr, Elmhurst, IL

1:30 PM

Board # 1070

The Impact of the Protein C Pathway on the Hemostatic Response to Injury Varies With Physiologic Context

**Tanya T Marar** , Timothy J Stalker, Leonard Nettey, Chelsea N Matzko, Izmarie Poventud-Fuentes, Talid R Sinno, Lawrence F Brass, Maurizio Tomaiuolo, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 1071

Two Birds One Stone: Salvianolic Acid B Inhibits Coagulation And Platelet Aggregation

Miguel Neves, Univ of Toronto, Toronto, ON, Canada; Yiming Wang, St. Michael's Hosp, Toronto, ON, Canada; **Tiffany Ni** , Univ of Toronto, Toronto, ON, Canada; Xi Lei, St. Michael's Hosp, Toronto, ON, Canada; Tyler W Stratton, Univ of Toronto, Toronto, ON, Canada; Si-yang Yu, St. Michael's Hosp, Toronto, ON, Canada; Reid C Gallant, Univ of Toronto, Toronto, ON, Canada; Dan Zhang, St. Michael's Hosp, Toronto, ON, Canada; Xiaohong Xu, Univ of Toronto, Toronto, ON, Canada; Guangheng Zhu, St. Michael's Hosp, Toronto, ON, Canada; Yiping Wang, Lijiang Xuan, Jian Ding, Shanghai Inst of Materia Medica, Shanghai, China; Philip E Johnson, York Univ, Toronto, ON, Canada; Heyu Ni, St. Michael's Hosp, Toronto, ON, Canada

1:30 PM

Board # 1072

The Study of Morphology and Dynamics of Platelets in an Activation Process Using 3-D Quantitative Phase Imaging

SangYun Lee, KAIST, DaeJeon, Korea, Republic of; Seongsoo Jang, Asan Medical Ctr, Seoul, Korea, Republic of; **YongKeun Park** , KAIST, DaeJeon, Korea, Republic of

# Abstract Poster Session

## IN.APS.16 - Hot Topics in PCI II

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4262

Impact of Low-Density Lipoprotein Cholesterol in Patients With Chronic Kidney Disease Undergoing Percutaneous Coronary Intervention

Niklas Beyhoff, **Davide Cao** , Roxana Mehran, Moritz Blum, Samantha Sartori, Anastasios Roumeliotis, Ridhima Goel, Rishi Chandiramani, Icahn Sch of Med at Mount Sinai, New York, NY; Vishal Kapur, Choudhury Hasan, Javed Suleman, Srinivas Kesanakurthy, Mount Sinai Hosp, New York, NY; Usman Baber, George Dangas, Icahn Sch of Med at Mount Sinai, New York, NY; Asaad Akbar Khan, Prakash Krishnan, Nitin Barman, Joseph Sweeny, Jason C Kovacic, Samin K. Sharma, Annapoorna Kini, Mount Sinai Hosp, New York, NY

1:30 PM

Board # 4263

Culprit Only vs Multi-vessel Percutaneous Coronary Intervention in Patients With NSTE-ACS- A Meta-analysis of Randomized Controlled Trials

**Aaqib H Malik** , Syed Zaid, Westchester Medical Ctr, Valhalla, NY; Srikanth Yandrapalli, Westchester Medical Ctr, White Plains, NY; Suchith Shetty, Univ of Iowa, Iowa City, IA; Senada Malik, Univ of New England, Portland, ME; Wilbert S Aronow, New York Medical Coll, New Rochelle, NY; Cenap Undemir, Ahmad Hasan, Westchester Medical Ctr, Valhalla, NY

1:30 PM

Board # 4264

Impact of Syntax Score on 7-year Clinical Outcomes in Patients Treated With Cobalt-chromium Everolimus-eluting Stent

**Takashi Hiromasa** , Shoichi Kuramitsu, Kokura Memorial Hosp, Kitakyushu, Japan; Takenori Domei, Kokura Memorial Hosp, Kitakyusyu, Japan; Kyohei Yamaji, Kokura Memorial Hosp, Kitakyshu, Japan; Yoshimitsu Soga, Shinichi Shirai, Kenji Ando, Kokura Memorial Hosp, Kitakyushu, Japan

1:30 PM

Board # 4265

Long-term Outcomes of 2nd Generation DES Compared to BMS in Patients With Acute Myocardial Infarction- A Meta-Analysis of Randomized Controlled Trials

**Aaqib H Malik** , Syed Zaid, Westchester Medical Ctr, Valhalla, NY; Srikanth Yandrapalli, Westchester Medical Ctr, White Plains, NY; Wilbert S Aronow, New York Medical Coll, New Rochelle, NY; Cenap Undemir, Hasan Ahmad, Westchester Medical Ctr, Valhalla, NY

1:30 PM

Board # 4266

Accuracy of PARIS Score and of PCI Complexity to Predict Ischemic Events in Patients Treated With Very Thin Stents on Unprotected Left Main or Coronary Bifurcations: Insights From the Rain Registry

**Guglielmo Gallone** , Fabrizio D'Ascenzo, Federico Conrotto, Ovidio De Filippo, Città della Salute e della Scienza, Torino, Turin, Italy; Francesco Costa, Policlinic "G. Martino", Univ of Messina, Messina, Italy; Saverio Muscoli, Tor Vergata Univ of Rome, Rome, Italy; Yoichi Imori, Nippon Medical Sch, 1-1-5, Sendagi, Bunkyo-ku, Tokyo, Japan; Giorgio Quadri, Infermi Hosp, Rivoli, Italy; Ivan Nuñez-Gil, Hosp Clínico San Carlos, IDISSC, and Univ Complutense de Madrid, Madrid, Spain; Giacomo Boccuzzi, S.G. Bosco Hosp, Torino, Turin, Italy; Nicola Ryan, Hosp Clínico San Carlos, IDISSC, and Univ Complutense de Madrid, Madrid, Italy; Carlo Di Mario, Royal Brompton Hosp, London, United Kingdom; Javier Escaned, Hosp Clinico San Carlos, Madrid, Spain; Gaetano M De Ferrari, Città della Salute e della Scienza, Univ of Turin, Turin, Italy

1:30 PM

Board # 4267

Dk-Crush Stenting Increases the Risk of Incomplete Stent Apposition Compared With Culotte Stenting for the Treatment of Left Main Coronary Bifurcation Lesion: Analysis From Micro CT

**Yutaka Hikichi** , Saga Univ Sch of Med, Saga, Japan; Kaito Matsubara, Kouta Sugiyama, Xiaodong Zhu, Waseda Univ, Shinjyuku, Tokyo, Japan; Yusuke Tsuboko, Waseda Univ, Shinjyuku Tokyo, Japan; Yuki Matsuhashi, Waseda Univ, Synjyuku, Tokyo, Japan; Yohei Inoue, Masahiro Natsuaki, Koichi Node, Saga Univ Sch of Med, Saga, Japan; Kiyotaka Iwasaki, Waseda Univ, Shinjyuku, Tokyo, Japan

1:30 PM

Board # 4268

Usefulness of External Elastic Lamina-Based Stent Sizing Criteria Using Optical Coherence Tomography

**Naotaka Okamoto** , Hiroaki Nohara, Naoko Higashino, Taku Toyoshima, Kohei Ukita, Akito Kawamura, Kyosuke Yanagawa, Osaka Rosai Hosp, Sakai, Osaka, Japan; Hitoshi Nakamura, Yutaka Matsuhiro, Koji Yasumoto, Akihiro Tanaka, Yasuharu Matsunaga, Daisuke Nakamura, Masamichi Yano, Masaki Yamato, Yasuyuki Egami, Ryu Shutta, Osaka Rosai Hosp, Sakai, Japan; Masami Nishino, Osaka Rosai Hosp, Sakai Osaka, Japan; Jun Tanouchi, Osaka Rosai Hosp, Sakai, Osaka, Japan

1:30 PM

Board # 4269

Aggressive Stent Sizing Can Avoid Stent Under-Expansion: An Optical Coherence Tomography Analysis

**Yutaka Matsuhiro** , Masami Nishino, Yasuyuki Egami, Ryu Shutta, Jun Tanouti, Osaka Rousai Hosp, Sakai, Japan

1:30 PM

Board # 4270

Proteinuria as a Predictor of Contrast Induced Acute Kidney Injury Following Coronary Angiography

Jayakumar Sreenivasan, New York Medical Coll, Valhalla, NY; Heyi Li, Mayo Clinic, Rochester, MN; Mohammad Shahzeb Khan, John H Stroger Jr Hosp of Cook, Chicago, IL; **Tauseef Akhtar** , Juan Del Cid Fratti, Kifah Hussain, Cook County Hosp, Chicago, IL; Min Zhuo, Beth Israel Deaconess Medical Ctr, Boston, MA; Neha Yadav, Cook County Hosp, Chicago, IL

1:30 PM

Board # 4271

"FFR at Rest": Characterizing Patients With Severe Coronary Stenosis and Maximal Vasodilation at Rest

**Srikanth Vallurupalli** , Shivkumar Agarwal, Univ of Arkansas for Medical Sciences, Little Rock, AR; Rimsha Hasan, UAMS, Little Rock, AR; Mohammed Eid Madmani, Aisha Siraj, Univ of Arkansas, Little Rock, AR; Rahil Rafeedheen, Mohamed Ayan, Negar Salehi, Malek Al-Hawwas, Univ of Arkansas for Medical Sciences, Little Rock, AR; Abdul Hakeem, Cincinnati, OH; Barry F Uretsky, Cincinnati, OH, Fort Smith, AR

1:30 PM

Poster Professor

Jacqueline E Tamis-Holland, New York, NY

# Abstract Poster Session

## LF.APS.12 - Implications and Applications of Physical Activity and Exercise

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3128

Sedentary Behavior and Atrial Fibrillation in the Objective Physical Activity and Cardiovascular Health (OPACH) Study

**Brian C Boursiquot** , Stanford Univ Sch of Med, Stanford, CA; John Bellettiere, UCSD, San Diego, CA; Michael J Lamonte, Univ at Buffalo - SUNY, Buffalo, NY; Andrea Z Lacroix, Univ of California San Diego, La Jolla, CA; Marco Valentin Perez, Stanford Univ, San Jose, CA

1:30 PM

Board # 3129

Physical Activity and Mortality Among Male Survivors of Myocardial Infarction

**Laila Al-Shaar** , Yanping Li, Harvard Univ, Boston, MA; Eric B Rimm, Harvard Sch Public Health, Boston, MA; Joann E Manson, Harvard Medical Sch, Boston, MA; Rosner Bernard, Harvard Univ, Boston, MA; Frank Hu, Harvard Sch of Public Health, Boston, MA; Meir Jonathan Stampfer, Walter Willett, Harvard Univ, Boston, MA

1:30 PM

Board # 3130

Physical Activity and Biomarkers of Inflammation: The Genetic Epidemiology Network of Arteriopathy (GENOA) Study

**Daisuke Kamimura** , Yokohama City Univ Hosp, Yokohama, Japan; Seth T Lirette, Jackson, MS; B. Gwen Windham, Univ of Mississippi Medical Ctr, Jakson, MS; Iftikhar J Kullo, Mayo Clinic, Rochester, MN; Donald CLARK III, Takeki Suzuki, Univ of Mississippi Medical Ctr, Jackson, MS; Adebamike Adedayo Oshunbade, Univ of Mississippi Medical C, Jackson, MS; Arsalan Hamid, UMMC, New City, NY; Javed Butler, Kenneth R Butler Jr., Thomas Mosley, Michael E Hall, Univ of Mississippi Medical Ctr, Jackson, MS

1:30 PM

Board # 3131

The Effect Of The California Wildfires On Daily Step Counts

**David G Rosenthal** , Geoffrey H Tison, Robert Avram, Eric Vittinghoff, Mark J Pletcher, Jeffrey E Olgin, Donald J Grandis, Gregory M Marcus, UCSF, San Francisco, CA

1:30 PM

Board # 3132

All-Extremity High-Intensity Interval Training Reduces Net Arterial Load on Left Ventricle in Older Adults With Type 2 Diabetes

**Chueh-Lung Hwang** , Jisok Lim, Han-Kyul Kim, Jeung-Ki Yoo, Univ of Florida, Gainesville, FL; Moon-Hyon Hwang, Incheon Natl Univ, Incheon, Korea, Republic of; Eileen M Handberg, Wilmer W Nichols, Demetra D Christou, Univ of Florida, Gainesville, FL

1:30 PM

Board # 3133

Prognostic Impact of Peak Oxygen Uptake and Heart Rate Reserve in Patients After Off-pump Coronary Artery Bypass Grafting

**Abidan Abulimiti** , Kazunori Shimada, Miho Yokoyama, Mitsuhiro Kunimoto, Tomomi Matsubara, Kei Fujiwara, Tatsuro Aikawa, Shohei Ouchi, Megumi Shimizu, Kosuke Fukao, Tomoyasu Kadoguchi, Tetsuro Miyazaki, Akie Shimada, Taira Yamamoto, Tetsuya Takahashi, Toshiyuki Fujiwara, Atsushi Amano, Hiruyuki Daida, Juntendo Univ Graduate Sch of Med, Tokyo, Japan

1:30 PM

Board # 3134

Peak Work Rate During Exercise Could Detect Frailty Status in Elderly Patients With Stable Heart Failure

**Akihiro Hirashiki** , Natl Ctr for Geriatrics, Obu, Japan; Atsuya Shimizu, Kazuhiro Kawashima, Kenichiro Nomoto, Natl Ctr for Geriatrics and Gerontology, Obu, Japan; Manabu Kokubo, Natl Ctr for Geriatrics and Gerontology, Ohbu, Japan; Hidenori Arai, Natl Ctr for Geriatrics and Gerontology, Obu, Japan

1:30 PM

Board # 3135

Exercise Capacity and Chronotropic Incompetence in Patients After Mitral Valve Surgery

**Masanori Kanazawa** , Maiko Toyoda, Takahiro Seki, Atsuhiro Iguchi, Seisho Takahashi, Yuta Kagaya, Hiroki Saito, Kenjiro Sato, Koki Ito, Masanobu Miura, Masateru Kondo, Satoshi Kawatsu, Hideaki Endo, Katsuhiko Oda, Akihiro Nakamura, Iwate Prefectural Central Hosp, Morioka, Japan

1:30 PM

Board # 3136

Relationships Between Metaboreceptor Protein Expression and Metaboreflex Sensitivity in Healthy Adults

**Joshua R Smith** , Corey Hart, Joshua G Akinsanya, Ian R Lanza, Thomas P Olson, Mayo Clinic, Rochester, MN

1:30 PM

Board # 3137

Accuracy of Commercial Heart Rate Monitors in Runners: A Prospective Study

**Selena R Pasadyn** , Mohamad Soudan, Marc Gillinov, Penny Houghtaling, Cleveland Clinic, Cleveland, OH; Dermot Phelan, Cleveland Clinic Fndn, Cleveland, OH; Nicole Gillinov, Barbara Bittel, Cleveland Clinic, Cleveland, OH; Milind Desai, Cleveland Clinic, Solon, OH

1:30 PM

Poster Professor

Erin D Michos, Baltimore, MD

1:30 PM

Board # 3138

Trpv1 Responses to Heat and Induces Myogenic Differentiation

**Syotaro Obi** , Dokkyo Medical Univ, Tokyo, Japan; Teruo Inoue, Toshiaki Nakajima, Dokkyo Medical Univ, Tochigi, Japan

1:30 PM

Board # 3139

Malnutrition Risk and Cardiopulmonary Exercise Test Performance

Rani Kuttab, Joronia Chery, **Amanda R Vest** , Tufts Medical Ctr, Boston, MA

1:30 PM

Board # 3140

Effects of Aerobic and Inspiratory Training on Skeletal Muscle Microrna-1 and Downstream-Associated Pathways in Patients With Systolic Heart Failure

Ligia M Antunes-Correa, Patricia Trevizan, Heart Inst - FMUSP, Sao Paulo, Brazil; Aline VN Bacurau, Sch of Physical Education and Sport, Univ of Sao Paulo, Sao Paulo, Brazil; Larissa Ferreira-Santos, Univ of Sao Paulo, Columbia, MO; João LP Gomes, Sch of Physical Education and Sport, Univ of São Paulo, Sao Paulo, Brazil; Ursula Urias, Heart Inst - FMUSP, Sao Paulo, Brazil; Patricia Oliveira, Heart Inst, Univ of Sao Paulo Medical Sch, Sao Paulo, Brazil; Maria-Janieire N Alves, Heart Inst USP, Sao Paulo, Brazil; Dirceu R Almeida, Federal Univ of São Paulo, Sao Paulo, Brazil; Patricia Chakur Brum, Usp-Eefe, Sao Paulo, Brazil; Edilamar Menezes Oliveira, USP, Sao Pulo, Brazil; Ludhmila Hajjar, Roberto Kalil Filho, **Carlos E Negrao** , Heart Inst, Sao Paulo, Brazil

# Abstract Poster Session

## EA.APS.35 - Improving Outcomes in Arrhythmia Patients

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2129

Long Term Cardiac Arrhythmia and Chronotropic Evaluation in Severe Anorexia Nervosa (lace-an): A Pilot Study

**Morteza Farasat** , Denver Health and Hosp Authority, Denevr, CO; Ashlie Watters, Denver Health and Hosp Authority, Aurora, CO; Joseph Schuller, Tiffany Bendelow, Denver Health and Hosp Authority, Denver, CO; Philip S Mehler, Univ of Colorado Sch of Med, Denver, CO; Mori J Krantz, Denver Health and Hosp Authority, Denver, CO

1:30 PM

Board # 2130

Frequency of Mitral Annular Disjunction and Prolapse in Patients Undergoing Premature Ventricular Contraction Ablation

**Neil Beri** , Patricia Takeda, Pankaj Malhotra, Xin Zhang, Dali Fan, Nayereh Pezeshkian, Uma Srivatsa, Univ of California Davis, Medical Ctr, Sacramento, CA

1:30 PM

Board # 2131

Outcomes of Combined Catheter Ablation and Left Atrial Appendage Closure for Atrial Fibrillation: A Systematic Review and Meta-Analysis

**Mahmoud El Iskandarani** , Bara El Kurdi, Ghulam Murtaza, East Tennessee State Univ, Johnson city, TN; Ali Bokhari, East Tennessee State Univ, Johnson City, TN; Marwan M Refaat, American Univ of Beirut Med Ctr, Beirut, Lebanon; Timir Paul, East Tennessee State Univ, Johnson City, TN

1:30 PM

Board # 2132

Relationship Between Epicardial Adipose Tissue and Catheter Ablation in Long-standing Persistent Atrial Fibrillation Patients

**Sen Matsumoto** , Masashi Ishimi, Kenki Ashida, Masataka Sugahara, Kenji Kawai, Nobutaka Masunaga, Nagahiro Nishikawa, Yoshiyuki Kijima, Tohru Masuyama, JCHO Hoshigaoka Medical Ctr, Hirakata, Japan

1:30 PM

Board # 2133

Prognostic Value of Cardiac Sympathetic Nerve Activity and Thyroid Stimulating Hormone in Paroxysmal Atrial Fibrillation With Catheter Ablation

**Masato Kawasaki** , Takahisa Yamada, Takashi Morita, Yoshio Furukawa, Shunsuke Tamaki, Atsushi Kikuchi, Tsutomu Kawai, Masahiro Seo, Kiyomi Kayama, Osaka General Medical Ctr, Osaka, Japan; Masatsugu Kawahira, Osaka General Medical Ctr, Oosaka, Japan; Kazuya Tanabe, Osaka General Medical Ctr, Osaka, NY

1:30 PM

Board # 2134

Lack of Long Term Efficacy of Sinus Node Modification for Inappropriate Sinus Tachycardia

**Samuel A. Shabtaie** , Chance M. Witt, Samuel J. Asirvatham, Mayo Clinic, Rochester, MN

1:30 PM

Board # 2135

Reduction in Atrial Fibrillation Burden After Ablation

**Lance S Longmore** , Univ of Kansas, Kansas City, KS; Nachiket Madhav Apte, Michael Pierpoline, Siva Sagar Taduru, KS; Ali Jazayeri, Seth Sheldon, Raghuveer Dendi, Rhea C Pimentel, Univ of Kansas Health System, Kansas City, KS; Martin Emert, Univ of Kansas, Kansas City, KS; Loren D Berenbom, Mid America Cardiology, Kansas City, KS; Madhu Reddy, Univ of Kansas Health System, Kansas City, KS

1:30 PM

Board # 2137

Recurrence After Atrial Fibrillation Ablation: Differential Impact of Vit K Antagonists vs. Non-vka Oral Anticoagulants

**Songnan Wen** , Mayo Clinic, Rochester, Minnesota, Rochester, MN; Cristina Pislaru, Mayo Clinic Coll of Med, Rochester, MN; Kristi H Monahan, Mayo Clinic - Rochester, Rochester, MN; Stephjanie Barnes, Mayo Clinic, Rochester, Minnesota, Rochester, MN; David Hodge, Mayo Clinic, Jacksonville, Florida, Jacksonville, FL; Douglas Packer, Mayo Clinic, Rochester, Minnesota, Rochester, MN; Samuel Asirvatham, Mayo Fndn, Rochester, MN; Sorin Pislaru, MAYO CLINIC, Rochester, MN

1:30 PM

Poster Professor

Bryan Baranowski

1:30 PM

Board # 2139

Impact of Sinus Node Recovery Time on the Outcome of Radiofrequency Catheter Ablation in Patients With Persistent Atrial Fibrillation: A Systematic Review and Meta-Analysis

**Mohamed Elmassry** , Texas Tech Univ Health Science Ctr, Lubbock, TX; Wasawat Vutthikraivit, Texas Tech Health Sciences Ctr, Lubbock, TX; Saif El Nawaa, Texas Tech Univ Health Science Ctr, Lubbock, TX; Pablo Paz, Texas Tech Univ Health Sciences Ctr, Lubbock, TX; Ahmed M. Souka, Univ of Cincinnati, Cincinnati, OH; Pattara Rattanawong, Univ of Hawaii, Honolulu, HI; Prapaipan Putthapiban, Einstein Medical Ctr, Philadelphia, PA; Haneen Mallah, Barbara Mantilla, M Rubayat Rahman, Mohammad Mehdi Ansari, Texas Tech Univ Health Science Ctr, Lubbock, TX; Scott W Shurmur, TEXAS TECH UNIV, Lubbock, TX

1:30 PM

Board # 2140

The Outcomes of Catheter Ablation for Hemodialysis Patients With Atrial Fibrillation

**Yuki Shimizu** , Yasuaki Tanaka, Takamitsu Takagi, Jun Nakajima, Kenji Okubo, Katsumasa Takagi, Hiroyuki Hikita, Atsushi Takahashi, Yokosuka Kyosai Hosp, Kanagawa, Japan

# Abstract Poster Session

## AT.APS.20 - Mechanisms of Atherosclerosis

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1040

Cardiorespiratory Responses to Juul and Tobacco Cigarettes in Mice: Role of Acrolein

**Daniel J Conklin** , Lexiao Jin, Katherine Whitehouse, Daniel Holbrook, Jordan Finch, Pawel Lorkiewicz, Sanjay Srivastava, Aruni Bhatnagar, Univ of Louisville, Louisville, KY

1:30 PM

Board # 1041

Alternative Autophagy is the Predominant Form of Autophagy in Estrogen-Mediated Mitochondrial Quality Control in Artery

**Yuichi Sasaki** , Yoshiyuki Ikeda, Yuichi Akasaki, Yoshihiro Uchikado, Mitsuru Ohishi, Kagoshima Univ, Kagoshima, Japan

1:30 PM

Board # 1044

Mild Hyperhomocysteinemia Neither Increased Atherosclerotic Plaque Burden Nor Altered Specific Histone Methylation in Aortas From Apolipoprotein E Knockout Mice

**Courtney A Whalen** , Floyd J Mattie, Kuan-Hsun Huang, Penn State Univ, University Park, PA; Cristina Florindo, Faculdade de Farmacia UL, Lisbon, Portugal; Sandra G Heil, Erasmus MC, Rotterdam, Netherlands; A. Catherine Ross, Thomas Neuberger, Rita Castro, Penn State Univ, University Park, PA

1:30 PM

Board # 1045

Sumoylation of Copper Chaperone Atox1 via Cysteine Oxidation of SENP1 as a Key Switch to Promote Atox1 Nuclear Translocation Driving Inflammation and Atherosclerosis

**Archita Das** , Sudhahar Varadarajan, David Fulton, Neal L Weintraub, Med. Coll. of Georgia at Augusta Univ, Augusta, GA; Jun-ichi Abe, Univ of Texas MD Anderson Cancer Ctr, Houston, TX; Masuko Ushio-Fukai, Tohru Fukai, Med. Coll. of Georgia at Augusta Univ, Augusta, GA

1:30 PM

Board # 1046

Characterization of an apoE-/- Mouse Model Expressing HLA-A*0201

Jianchang Zhou, Cedars-Sinai Medical Ctr, West Hollywood, CA; Xiaoning Zhao, Kuang-yuh Chyu, Paul C Dimayuga, Cedars-Sinai Medical Ctr, Los Angeles, CA; Wai Man Lio, Cedars-Sinai Medical Ctr, West Hollywood, CA; **Fernando Chernomordik** , Cedars-Sinai Medical Ctr, Los Angeles, CA; Juliana Yano, Cedars-Sinai Medical Ctr, West Hollywood, CA; Bojan Cercek, Prediman K Shah, Cedars-Sinai Medical Ctr, Los Angeles, CA

1:30 PM

Board # 1047

Comparison of In-Stent Responses Between Durable Polymer and Bioabsorbable Polymer Everolimus-Eluting Stent in a Human-Like Coronary Atherosclerotic Porcine Model

**Daisuke Kitano** , Yuxin Li, Suguru Migita, Hiroyuki Hao, Atsushi Hirayama, Yasuo Okumura, Nihon Univ Sch of Med, Tokyo, Japan

1:30 PM

Board # 1048

8-Hydroxyeicosapentaenoic AcidConcentrated Materials From Pacific Krill Suppresses Atherosclerosis in Apolipoprotein E-deficient Mice

Masamichi Hirose, Iwate Medical Univ, Shiwa-gun Iwate, Japan; **Miho Ibi** , Iwate Medical Univ, Shiwa-gun, Iwate, Japan; Maki Saito, Nanae Ishida, Iwate Medical Univ, Shiwa-gun Iwate, Japan

1:30 PM

Board # 1049

Targeted Activation of Peroxisome Proliferator-Activated Receptor Gamma (PPARG) Rapidly Suppresses Inflammation Through Inhibition of Toll-Like Receptor 4/Nuclear Factor-kappa B (TLR4/NF-kappa B) Pathway and Further Shifts Advanced Atheroma Into a Stable Phenotype

**Joon Woo Song** , Korea Univ, Seoul, Korea, Republic of; Hyeong Soo Nam, Hanyang Univ, Seoul, Korea, Republic of; Hyun-Sang Park, KAIST, Daejeon, Korea, Republic of; Sunwon Kim, Korea Univ Ansan Hosp, Seoul; Hyun Jung Kim, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Yeon Hoon Kim, Hanyang Univ, Seoul, Korea, Republic of; Jae Won Ahn, Chung-Ang Univ, Anseong-si, Gyeonggi-do, Korea, Republic of; Jah Yeon Choi, Korea Univ Guro Hosp, Seoul; Dong Oh Kang, Seung-Yul Lee, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Wang-Yuhl Oh, Hongki Yoo, KAIST, Daejeon, Korea, Republic of; Kyeongsoon Park, Chung-Ang Univ, Anseong-si, Gyeonggi-do, Korea, Republic of; Jin Won Kim, Korea Univ Guro Hosp, Seoul, Korea, Republic of

# Abstract Poster Session

## EA.APS.36 - Minimizing Complications of EP Procedures

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2141

Clinical Manifestations and Diagnostic Yield of Computed Tomography in Patients With Atrio-Esophageal Fistula Following Ablation for Atrial Fibrillation: A Literature Review

**Domenico Giovanni Della Rocca** , St. David's Medical Ctr, Austin, TX; Veronica Natale, Tcai, Austin; Sanghamitra Mohanty, Chintan G Trivedi, Texas Cardiac Arrhythmia Inst, Austin, TX; Bryan MacDonald, TCAI, Austin, TX; Carola Gianni, Texas Cardiac Arrhythmia Inst, Austin, TX; Mohamed Ahmed Bassiouny, Cleveland Clinic Fndn, Cleveland, OH; Amin Al-Ahmad, Texas Cardiac Arrhythmia Inst, Austin, TX; Rodney Paul Horton, TCAI, Austin, TX; Jorge Romero, Montefiore Albert Einstein, Bronx, NY; Nicola Tarantino, St. David's Medical Ctr, Austin, TX; David Burkhardt, TCaI, Austin, TX; Joe Gallinghouse, Tcai, Austin, TX; Luigi Di Biase Sr., Albert Einstein Coll of Med, New York, NY; Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

1:30 PM

Board # 2142

Factors Associated With Esophageal Injury After Catheter Ablation of Atrial Fibrillation

**Miwa Ito** , Hisanori Kanazawa, Yusuke Kanemaru, Kiyama Takuya, Yusei Kawahara, Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

1:30 PM

Board # 2143

Esophagus Temperature Monitoring Predicts Gastric Hypoperistalsis After Catheter Ablation for Atrial Fibrillation

**Ai Horiguchi** , Jun Oikawa, Hidehira Fukaya, Jun Kishihara, Takuya Wada, Daiki Saito, Tetsuro Sato, Gen Matsuura, Yuki Arakawa, Shuhei Kobayashi, Yuki Shirakawa, Ryo Nishinarita, Naruya Ishizue, Chikatoshi Katada, Satoshi Tanabe, Shinichi Niwano, Wang Ying, Kitasato Univ Sch of Med, Sagamihara, Japan

1:30 PM

Board # 2144

Catheter-Related Complications of Atrial Fibrillation Ablation Following Introduction of Contact Force-Sensing Technology

**Joseph Akar** , Yale Univ Sch of Med, New Haven, CT; James Hummel, Univ of Wisconsin, Madison, WI; Xiaoxi Yao, Lindsey R Sangaralingham, Mayo Clinic, Rochester, MN; Sanket Dhruva, UCSF Sch of Med, San Francisco, CA; Jun Dong, U. S.Food and Drug Admin, White Oak, MD; Rebecca Ward, Mimi Nguyen, U.S. Food and Drug Admin, White Oak, MD; Nilay Shah, Mayo Clinic, Rochester, MN; Joseph S Ross, Yale Univ Sch of Med, New Haven, CT; Peter Alexander Noseworthy, Mayo Clinic, Rochester, MN

1:30 PM

Board # 2145

Incidence of Pulmonary Vein Stenosis Following Cryoballoon Atrial Fibrillation Ablation in Patients With Variant Pulmonary Vein Anatomy

**Anas Abudan** , Univ of Kansas Medical Ctr, Kansas City, KS; Neil Phillips, Univ of Kansas, Kansas City, MO; Mohammad-Ali Jazayeri, Thomas O McCormack, Univ of Kansas Medical Ctr, Kansas City, KS; Tawseef Dar, Massachusetts General Hosp, Kansas City, KS; Bharath Yarlagadda, Michael Pierpoline, Martin Emert, Univ of Kansas Medical Ctr, kansas city, KS; Rhea C Pimentel, Univ of Kansas Health System, Kansas City, KS; Raghuveer Dendi, Loren D Berenbom, Madhu Reddy, Seth Sheldon, Univ of Kansas Medical Ctr, Kansas City, KS

1:30 PM

Board # 2147

Radiofrequency Guided Transseptal Needle Versus Conventional Transseptal Needle for Left Atrial Access for Catheter Based Electrophysiology Procedures

**Jalaj Garg** , Syeda Atiqa Batul, Mohit K Turagam, Poojita Shivamurthy, Manaswi Bhupesh Pathik, Kenji Kuroki, Aamir A Sofi, Georgios Syros, Marc Miller, Jacob Sam Koruth, Subbarao Choudry, Marie-Noelle Langan, Anthony Gomes, William Whang, Srinivas Dukkipati, Vivek Y Reddy, Icahn Sch of Med at Mount Sinai Medical Ctr, New York, NY

1:30 PM

Board # 2148

Effect of Myocardial Injury and Inflammation on Recurrence After Pulmonary Vein Isolation is Differentbetween Radiofrequency Catheter Ablation and Cryoballoon Ablation

**Masamichi Yano** , Masami Nishino, Hiroaki Nohara, Taku Toyoshima, Naoko Higashino, Kohei Ukita, Akito Kawamura, Kyosuke Yanagawa, Hitoshi Nakamura, Yutaka Matsuhiro, Koji Yasumoto, Naotaka Okamoto, Akihiro Tanaka, Daisuke Nakamura, Yasuharu Matsunaga, Masaki Yamato, Yasuyuki Egami, Ryu Shutta, Jun Tanouchi, Osaka Rosai Hosp, Sakai, Japan

1:30 PM

Board # 2149

Automated Annotation-Guided Radiofrequency Ablation Improves Learning Curve for Pulmonary Vein Isolation

**Nobuaki Tanaka** , Koichi Inoue, Koji Tanaka, Toshinari Onishi, Sakurabashi Watanabe Hosp, Osaka, Japan; Yuko Hirao, Sakurabashi-Watanabe Hosp, Osaka, Japan; Takafumi Oka, Masato Okada, Issei Yoshimoto, Sakurabashi Watanabe Hosp, Osaka, Japan; Ryo Kitagaki, Sakurabashi Watanabe Hosp, Osaka city, Japan; Katsuomi Iwakura, Sakurabashi Waturahe Hospi, Osaka, Japan; Kenshi Fujii, Sakurabashi Watanabe Hosp, Osaka, Japan

1:30 PM

Board # 2150

Real-life Safety of Atrial Flutter Ablation in the Era of Noacs. The French Global Flutter Study

**Walid Amara** , Dorsaf Mlayeh, Hosp Intercommunal Raincy, Montfermeil, France; Rodrigue Garcia, Hosp of Poitiers, Poitiers, France; Jérome Taieb, Hosp of Aix en Provence, Aix en Provence, France; François Jourda, Hosp of Auxerre, Auxerre, France; Claire Falaise, Hosp of La Rochelle, La Rochelle, France; Frédéric Georger, Hosp of Béziers, Béziers, France; Antoine Milhem, Hosp of La Rochelle, La Rochelle, France

1:30 PM

Poster Professor

James Patrick Daubert, Durham, NC

1:30 PM

Board # 2151

Perioperative Coronary Artery Spasms in Patients With Radiofrequency Catheter Ablation of Atrial Fibrillation Under Deep Sedation

**Masato Hachisuka** , Yuhi Fujimoto, Yu-ki Iwasaki, Rei Mimuro, Eiichiro Oka, Hiroshi Hayashi, Hiroshige Murata, Teppei Yamamoto, Akinori Sairaku, Kenji Yodogawa, Wataru Shimizu, Nippon Medical Sch, Tokyo, Japan

1:30 PM

Board # 2152

Proper Precautionary Measures Can Prevent Thermal Injury to Esophagus During Ablation of Coronary Sinus in Patients With Atrial Fibrillation

**Sanghamitra Mohanty** , Chintan Gautambhai Trivedi, Domenico Giovanni Della Rocca, Carola Gianni, Texas Cardiac Arrhythmia Inst, Austin, TX; Ugur Canpolat, Hacettepe Univ, Ankara, Turkey; Bryan MacDonald, John David Burkhardt, Javier Sanchez, Patrick Hranitzky, G Gallinghouse, Amin Al-ahmad, Rodney Paul Horton, Mohammed Bassiouny, Texas Cardiac Arrhythmia Inst, Austin, TX; Luigi Di Biase, Albert Einstein Coll of Med, New York, NY; Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

# Abstract Poster Session

## IM.APS.17 - MRI: General Topics

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Daniel Vargas, Denver, CO

1:30 PM

Board # 4212

Automated Cardiac Magnetic Resonance Imaging

**Alfredo S De Goyeneche** , Nii O Addy, Juan M Santos, HeartVista, Los Altos, CA; Bob Hu, Palo Alto Medical Fndn, Palo Alto, CA

1:30 PM

Board # 4213

Multiparametric Cardiac Magnetic Resonance Imaging to Detect Cardiac Allograft Vasculopathy Beyond the First Year Post-heart Transplantation

**Muhannad Abbasi** , Northwestern, Chicago, IL; Roberto Sarnari, Northwestern Univ, Chicago, IL; Arif Jivan, Northwestern Memorial Hosp, Chicago, IL; Rahim Gulamali, Julie Blaisdell, Northwestern, Chicago, IL; Kongkiat Chaikriangkrai, 6550 Fannin Street, Houston, TX; Alexander Ruh, Northwestern, Chicago, IL; Daniel Lee, Northwestern Univ Medical Sch, Chicago, IL; Kambiz Ghafourian, Jane E Wilcox, Northwestern Univ, Chicago, IL; Sadiya S. Khan, Northwestern Univ, Oak Park, IL; Esther Vorovich, Northwestern, Chicago, IL; Jonathan Rich, Northwestern Univ, Skokie, IL; Allen S Anderson, Clyde W Yancy, James C carr, Michael Markl, Northwestern Univ, Chicago, IL

1:30 PM

Board # 4214

Non-invasive Measurement of Ascending Aorta Impedance Using Cardiac Magnetic Resonance and Applanation Tonometry as the Optimal Guide to Assess the Severity of Aortic Valve Stenosis

**Sara L Hungerford** , Audrey I Adji, Nicole K Bart, Linda Lin, Bruno Schnegg, Mayooran J Namasivayam, Michael F O'Rourke, Andrew Jabbour, Christopher S Hayward, David W.M Muller, St Vincent's Hosp, Sydney, Australia

1:30 PM

Board # 4215

Increased Liver Stiffness Assessed by Magnetic Resonance Elastography Predicts Elevated Right Atrial Pressure in Patients With Heart Failure

**Yoshiya Kato** , Hokkado Univ Hosp, Sapporo, Japan; Toshiyuki Nagai, Noriko Oyama-Manabe, Satonori Tsuneta, Hokkaido Univ Hosp, Sapporo, Japan; Yuta Kobayashi, Hokkaido Univ Hosp, Sapporo,, Japan; Hirokazu Komoriyama, Hokkado Univ Hosp, Sapporo, Japan; Kazunori Omote, Shingo Tsujinaga, Tadao Aikawa, Hokkaido Univ, Sapporo, Japan; Takuma Sato, Hokkaido Univ Hosp, Sapporo, Japan; Takao Konishi, Hokkaido Unversity, Sapporo, Japan; Kiwamu Kamiya, Hiroyuki Iwano, Hokkaido Univ, Sapporo, Japan; Toshihisa Anzai, Hokkaido Univ Hosp, Sapporo, Japan

1:30 PM

Board # 4216

Prognostic Implications of Feature Tracking Global Longitudinal Strain in Patients With Preserved Ejection Fraction and No Late Gadolinium Enhancement: A Multicenter Study

**Kaleigh L. Evans** , Univ of Illinois, Chicago, IL; Simone Romano, Univ of Illinois, Chicago, chicago, IL; Robert M Judd, Raymond J Kim, Duke Univ Medical Ctr, Durham, NC; John F Heitner, NYP Brooklyn Methodist Hosp, Brooklyn, NY; Dipan J Shah, Houston Methodist Hosp, Houston, TX; Benjamin Romer, Pablo Salazar, Afshin Farzaneh-Far, Univ of Illinois Chicago, Chicago, IL

1:30 PM

Board # 4217

Automatic Segmentation of Left Ventricular Myocardium and Scar From Lge-cmr Images Utilizing Deep Learning With Weighted Categorical Cross Entropy Loss Function Weight Initialization

**Vivek P Jani** , Johns Hopkins Univ, Baltimore, MD; Mohammad R Ostovaneh, Johns Hopkins Medical Insts, Baltimore, MD; Ela Chamera, Joao A Lima, Bharath Ambale-Venkatesh, Johns Hopkins Univ, Baltimore, MD

1:30 PM

Board # 4218

**CMR Effects on Pacemaker/ ICDStability; An i** n vivo **Study**

**Robert W Biederman** , Loretta Gevenosky, Ronald Williams, Richard Lombardi, Christopher Bonnet, Moneal Shah, Mark Doyle, Allegheny General Hosp, Pittsburgh, PA

1:30 PM

Board # 4219

Prognostic Value and Natural History of Cardiovascular Magnetic Resonance Derived Myocardial Extracellular Volume in Heart Transplant Patients

**Muhannad Abbasi** , Northwestern, Chicago, IL; Roberto Sarnari, Northwestern Univ, Chicago, IL; Kongkiat Chaikriangkrai, 6550 Fannin Street, Houston, TX; Sadiya S. Khan, Northwestern Univ, Oak Park, IL; Kambiz Ghafourian, Jane E Wilcox, Northwestern Univ, Chicago, IL; Esther Vorovich, Northwestern, Wilmette, IL; Daniel Lee, Northwestern Univ Medical Sch, Chicago, IL; Jonathan Rich, Northwestern Univ, Skokie, IL; Allen S Anderson, Clyde W Yancy, James C carr, Michael Markl, Northwestern Univ, Chicago, IL

1:30 PM

Board # 4220

Automated Aortic Analysis Using MRI and Deep Learning: The Multi-Ethnic Study of Atherosclerosis (MESA)

**Vivek P Jani** , Johns Hopkins Univ, Baltimore, MD; Gisela Texido-Tura, Hosp Vall d'Hebron, Barcelona, Spain; Nadjia Kachenora, Kevin Bouaou, Sorbonne Univ, INSERM, CNRS, Paris, France; Alain De Cesare, Sorbonne Univ, INSERM, CNRS,, Paris, France; Shelby Kutty, Johns Hopkins Med, Baltimore, MD; Colin Wu, Natl Insts of Health, Bethesda, MD; David Bluemke, Univ of Wisconsin Sch of Med, Madison, WI; Joao A Lima, Bharath Ambale-Venkatesh, Johns Hopkins Univ, Baltimore, MD

1:30 PM

Board # 4222

Prediction of the Response to Beta-blocker Therapy in Patients With Dilated Cardiomyopathy Using T1 Mapping on Cardiovascular Magnetic Resonance

**Yumiko Kanzaki** , Yusuke Nishida, Daichi Maeda, Osaka Medical Coll, Takatsuki, Japan; Kosuke Tsuda, Osaka Medical Coll, Osaka, Japan; Takahide Ito, Osaka Medical Coll, Takatsuki, Japan; Koichi Sohmiya, Masaaki Hoshiga, Osaka Medical Coll, Osaka, Japan

1:30 PM

Board # 4223

Role of Cardiovascular Magnetic Resonance in Prediction of Atrial Fibrillation: Construction of a Risk Prediction Score

**Alphonsus C Liew** , Claire E Raphael, Frances Mitchell, Gajen S Kanaganayagam, Elisa C Di Pietro, Royal Brompton Hosp, London, United Kingdom; Simon Newsome, London Sch of Hygiene & Tropical Med, London, United Kingdom; Robert Cooper, Ruth Owen, Peter Gatehouse, Vassilis Vassiliou, Royal Brompton Hosp, London, United Kingdom; Michael Frenneaux, Univ of East Anglia, Norwich, United Kingdom; Rory O'Hanlon, Dudley Pennell, Sanjay Prasad, Royal Brompton Hosp, London, United Kingdom

1:30 PM

Board # 4224

Cardiac Magnetic Resonance Clinical Impact in Management of Cardiomyopathy in a Cancer Center

**Giv Heidari Bateni** , Jean-Bernard Durand, Cezar Iliescu, Elie Mouhayar, Nicolas Lawrence Palaskas, Gregory Gladish, Jawad Chohan, Daryl Sudasena, Saamir Hassan, Peter Kim, Purvi Parwani, Mohammad-Ali Jazayeri, Juan Lopez-Mattei, Univ of Texas MD Anderson Cancer Ctr, Houston, TX

1:30 PM

Board # 4225

Extracellular Volume Fraction and Native T1 Time Evaluated by Cardiac Magnetic Resonance Imaging for Evaluating the Severity of Patients With Non-Ischemic Cardiomyopathy

**Sho Kodama** , Shingo Kato, Keigo Hayakawa, Mai Azuma, Minako Kagimoto, Kohei Iguchi, Masahiro Fukuoka, Kanagawa Cardiovascular and Respiratory Ctr, Yokohama, Japan; Kazuki Fukui, Kanagawa Prefectual Cardiovascular and Respiratry, Yokohama, Japan; Tae Iwasawa, Kanagawa Cardiovascular and Respiratory Ctr, Yokohama, Japan; Daisuke Utsunomiya, Yokohama City Univ, Yokohama, Japan; Masami Kosuge, Kazuo Kimura, Yokohama City Univ Medical Ctr, Yokohama, Japan; Kouichi Tamura, Yokohama City Univ, Yokohama, Japan

1:30 PM

Board # 4226

Non-contrast T1, T2 and T2 Star Mapping in Patients With Dilated Cardiomyopathy: Comparison With Late Gadolinium Enhancement

Yumiko Kanzaki, **Tomohiko Watanebe** , Daichi Maeda, Takahide Ito, Osaka Medical Coll, Takatsuki, Japan; Koichi Sohmiya, Masaaki Hoshiga, Osaka Medical Coll, Osaka, Japan

# Abstract Poster Session

## CA.APS.06 - Myocardial Ischemia

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Maria Irene Kontaridis, Utica, NY

1:30 PM

Board # 1107

Ischemic Myocardium-Derived Cell-Free DNA Activates the Type I Interferon Signaling Pathway and Mediates Reperfusion Injury

**Aimee Zhang** , Lina Lai, Eric J Charles, Univ of Virginia, Charlottesville, VA; Irving L Kron, Univ of Arizona, Tuscon, AZ; Zequan Yang, Univ of Virginia, Charlottesville, VA

1:30 PM

Board # 1108

The Synergy Between Angiopietin-1 and Cardiomyocyte Constitutes a Better Therapeutic Approach for Treatment of Myocardial Infarction

**Zhonghao Tao** , Nanjing First Hosp, Nanjing Medical Univ, Nanjing, China; Szejie loo, Liping Su, Shihua Tan, Nicole Tee, Natl Heart Ctr Singapore, Singapore, Singapore; ShuUin Gan, Natl Univ of Singapore, Singapore, Singapore; Xin Chen, Nanjing First Hosp, Nanjing Medical Univ, Nanjing, China; Lei Ye, Natl Heart Ctr Singapore, Singapore, Singapore

1:30 PM

Board # 1110

S-nitrosylation Promotes Cell Cycle, Cell Viability and Proliferation by Activating the Snail/Slug Pathway in miPSC-Derived CM

**Alessandro Salerno** , Amarylis Bonito Wanschel, Konstantinos E. Hatzistergos, Univ of Miami, Miami, FL; Raul A Dulce, Interdisciplinary Stem Cell Inst, Miami, FL; Wayne Balkan, Univ Miami Miller Sch, Miami, FL; Joshua M Hare, Univ of Miami, Miami, FL

1:30 PM

Board # 1111

GSK3β-Dependent Phosphorylation of CypD and PTP Regulation During Myocardial Infarction

Stephen Hurst, Thomas Jefferson Univ, Philadelphia, PA; Fabrice Gonnot, Claire Crola Da Silva, **Ludovic Gomez** , INSERM U1060, Bron, France; Shey-shing Sheu, Sidney Kimmel Medical Coll, Philadelphia, PA

1:30 PM

Board # 1112

Ivabradine Induces Cardiac Protection by Preventing Inflammatory Response Through Inhibition of Cyclophilin-A Secretion After Myocardial Ischemia/Reperfusion Injury

Ignacio Hernandez Navarro, Rafael Ramirez-Carracedo, Laura Tesoro, Javier Diez Mata, Univ Francisco de Vitoria, Pozuelo de Alarcon, Spain; Ricardo Garcia De la P, Hosp Univrio Ramón y Cajal (IYICIS), Madrid, Spain; Paula Reventun, Univ Alcala, Alcala de Henares; Jose L Zamorano, Hosp Univrio Ramon y Cajal (IYICIS), Madrid, Spain; Marta Saura, Univ de Alcala, Alcala De Henares Madrid, Spain; **Carlos Zaragoza** , Univ Francisco de Vitoria, Pozuelo de Alarcon, Spain

1:30 PM

Board # 1113

Tsg101 Promotes Translocation of Glucose Transporter-4 in Ischemic Hearts

**Kobina Essandoh** , Shan Deng, Xiaohong Wang, Xingjiang Mu, Univ of Cincinnati, Cincinnati, OH; Yutian Li, Univ of Cincinnati Coll of Med, Cincinnati, OH; Guo-chang Fan, Univ of Cincinnati, Cincinnati, OH

1:30 PM

Board # 1114

Podoplanin Neutralization Improves Cardiac Remodeling and Function After Myocardial Infarction

**Maria Cimini** , Venkata Garikipati, Claudio De Lucia, Zhongjian Cheng, Chunlin Wang, May Truongcao, Anna Maria Lucchese, Cindy Benedict, Temple Univ,Lewis Katz Sch, Philadelphia, PA; David Goukassian, Icahn Sch of Med at Mount Sinai, New York City, NY; Walter Koch, Raj Kishore, Temple Univ,Lewis Katz Sch, Philadelphia, PA

# Abstract Poster Session

## EA.APS.30 - New Insights into Ventricular Arrhythmia Ablation

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2074

Need for Hemodynamic Support in High-risk Patients Undergoing Vt Ablation With Substrate-based Approach

**Sanghamitra Mohanty** , Chintan G Trivedi, Domenico Giovanni Della Rocca, Mohammed Bassiouny, Ugur Canpolat, Carola Gianni, Bryan MacDonald, Texas Cardiac Arrhythmia Inst, Austin, TX; Javier Sanchez, Texas Cardiac Arrhythmia Inst, austin, TX; Joe Gallinghouse, John David Burkhardt, Rodney Paul Horton, Amin Al-ahmad, Texas Cardiac Arrhythmia Inst, Austin, TX; Jorge Romero, Montefiore Albert Einstein, Bronx, NY; Luigi Di Biase, Albert Einstein Coll of Med, New York, NY; Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

1:30 PM

Board # 2075

Conventional vs Fluoroless Catheter Ablation in Premature Ventricular Contractions: A Single Center Experience

Araba Bruce-mensah, UVA Medical Ctr, Charlottesville, VA; **Brittney Heard** , UVA Health System, Charlottesville, VA; Pamela Mason, Rohit Malhotra, Kenneth Bilchick, UVA Medical Ctr, Charlottesville, VA; John Ferguson, SCL Health Heart & Vascular Inst, Denver, CO; J. Michael Mangrum, Andrew Darby, Nishaki Mehta, UVA Medical Ctr, Charlottesville, VA

1:30 PM

Board # 2076

Hospitalization Rates Following Catheter Ablation for Ventricular Tachycardia: Insights From the Nationwide Readmission Database

**Ahmed Elkaryoni** , Univ of Missouri-Kansas City, Kansas City, MO; Alan P Wimmer, Saint-Luke's Mid America Heart Inst/ Univ of Missouri- Kansas City, Kansas City, MO

1:30 PM

Board # 2077

Isolated Epicardial Electrogram Abnormalities in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC): Implications for Diagnosis and Treatment

**Cory M Tschabrunn** , Pasquale Santangeli, Univ of Pennsylvania, Philadelphia, PA; David S Frankel, Univ of Pennsylvania Health System, Philadelphia, PA; Erica S Zado, Hosp of the Univ of PA, Philadelphia, PA; David J Callans, Hosp Univ Pennsylvania, Washington Crossing, PA; Francis E Marchlinski, Univ of Pennsylvania, Bala Cynwyd, PA

1:30 PM

Board # 2078

Efficacy and Safety of Ablation versus Medication for Treatment of Recurrent Ventricular Tachycardia in Patients With Left Ventricular Assist Devices

**Rachel L Debenham** , Univ of Colorado, Aurora, CO; Ryan Cotter, Univ of Colorado, Aurora; Alexis Z Tumolo, Amneet Sandhu, Univ of Colorado, Denver, CO; Ryan G Aleong, Ryan Borne, Univ of Colorado, Aurora, CO; Blake Fleeman, Univ of Colorado Denver, Denver, CO; Nicholas Mantini, Univ of Colorado Denver, Aurora, CO; Brian Miller, Univ of Colorado, Aurora, CO; Shu Chang, Univ of Colorado Denver, Denver, CO; Andreas Brieke, Eric Butcher, Christine Tompkins, Univ of Colorado, Aurora, CO; Matthew Zipse, Univ of Colorado, Denver, CO; Wendy S Tzou, Univ of Colorado, Aurora, CO

1:30 PM

Board # 2079

Quantifying the Benefit of Cardiac Sympathetic Denervation in Patients With Monomorphic Ventricular Tachycardia Referred for Catheter Ablation: An Effect Size Analysis

**Veronica Dusi** , UCLA Cardiac Arrhythmia Ctr, Los Angeles, CA; Jeffrey Gornbein, UCLA Depts of Med and Computational Med, David Geffen Sch of Med, Los Angeles, CA; Julie Sorg, Houman Khakpour, Yuliya Krokhaleva, Olujimi A Ajijola, Carlos Macias, Jason S Bradfield, Eric F Buch, Osamu A Fujimura, Noel G Boyle, UCLA Cardiac Arrhythmia Ctr, Los Angeles, CA; Jane Yanagawa, Jay M Lee, UCLA Div of Thoracic Surgery, Los Angeles, CA; Kalyanam Shivkumar, Marmar Vaseghi, UCLA Cardiac Arrhythmia Ctr, Los Angeles, CA

1:30 PM

Board # 2080

Association of Septal Scar Substrates on Late Gadolinium Enhanced Cardiac Magnetic Resonance With Ventricular Tachycardia Targets in Nonischemic Cardiomyopathy

**Ling Kuo** , Jackson J Liang 19104, HUP, Philadelphia, PA; David S Frankel, Univ of Pennsylvania Health System, Philadelphia, PA; Robert D Schaller, Gregory Supple, Univ of Pennsylvania, Philadelphia, PA; Fermin Carlos Garcia, Hosp of the Univ of Pennsylvania, Philadelphia, PA; Sanjay Dixit, Hosp of the Univ of Pennsylvania, Wynnewood, PA; David Lin, Hosp of The Univ of Pennylvania, Philadelphia, PA; Pasquale Santangeli, Jeffrey Arkles, Hosp of the Univ of Pennsylvania, Philadelphia, PA; Michael P Riley, Hosp Univ Pennsylvania, Philadelphia, PA; David J Callans, Hosp Univ Pennsylvania, Washington Crossing, PA; Erica S Zado, Hosp of The Univ of PA, Philadelphia, PA; Yuchi Han, Univ of Pennsylvania, Philadelphia, PA; Francis E Marchlinski, Univ of Pennsylvania, Bala Cynwyd, PA; Benoit Desjardins, Hosp of the Univ of Pennsylvania, Philadelphia, PA; Saman Nazarian, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 2081

Clinical Predictors of Ventricular Tachycardia Induced Cardiomyopathy

**Zahra Azizi** , Southlake Regional Health Ctr, Aurora, ON, Canada; Pouria Alipour, Southlake Regional Health Ctr, Newmarket, ON, Canada; Hadi Tohidi, Southlake Regional Health Ctr, Aurora, ON, Canada; Yaariv Khaykin, Southlake Regional Health Ctr, Richmond Hill, ON, Canada; Andrea Chiocchini, Southlake Regional Health Ctr, Newmarket, ON, Canada; Maria Terricabras, Southlake Regional Health Ctr, Aurora, ON, Canada; Atul Verma, Southlake Regional Health Ctr, Newmarket, ON, Canada

1:30 PM

Board # 2082

In vivo Bipolar Radiofrequency Ablation Creates Larger and Denser Lesions, Compared to Sequential and Simultaneous Unipolar Ablation Respectively

**Duy Nguyen** , Lijun Zheng, Univ Colorado, Aurora, CO; Meg Babakhanian, Paul J Wang, Stanford Univ, Stanford, CA

1:30 PM

Board # 2083

Non-Inducibility of Any Ventricular Tachycardia Soon After Radiofrequency Ablation Predicts Long-Term Recurrence of Ventricular Arrhythmia in Patients With Reduced Left Ventricular Ejection Fraction

**Masayoshi Kiyokuni** , Tabito Kino, Yokohama City Univ, Yokohama, Japan; Syuuichi Miyagawa, Fujisawa City Hosp, Fujisawa, Japan; Masatoshi Narikawa, Yuuka Taguchi, Yokohama City Univ, Yokohama, Japan; Naoki Nakayama, Yokohama City Univ Hosp, Yokohama, Japan; Junya Hosoda, Yokohama City Univ, Yokohama, Japan; Hideto Yano, Gyoutoku General Hosp, Fujisawa, Japan; Katsumi Matsumoto, Teruyasu Sugano, Tomoaki Ishigami, Toshiyuki Ishikawa, Yokohama City Univ, Yokohama, Japan; Kouichi Tamura, Yokohama City Univ Sch of Med, Yokohama, Japan; Kazuo Kimura, Yokohama City Univ Medical Ce, Yokohama, Japan

1:30 PM

Poster Professor

Edmond Cronin, Hartford, CT

# Abstract Poster Session

## HF.APS.40 - New Therapies in Heart Failure and Cardiomyopathy

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2252

Use of Tumor Necrosis Factor Alpha Inhibitors for Treatment of Refractory Cardiac Sarcoidosis

**Alison L Wand** , David Okada, Jan M Griffin, Harikrishna S Tandri, Jonathan Chrispin, Farooq H Sheikh, Edward K Kasper, Edward Chen, Nisha A Gilotra, Johns Hopkins Sch of Med, Baltimore, MD

1:30 PM

Board # 2253

Differential Transthyretin Binding, Kinetic Stability and Additive Ex Vivo Stabilization by AG10 Compared to Tafamidis

Alan X Ji, Paul W Wong, Andreas Betz, **Uma Sinha** , Eidos Therapeutics Inc, San Francisco, CA

1:30 PM

Board # 2255

Empagliflozin, a SGLT2 Inhibitor, Directly Protects Cardiomyocytes by Off-Target Effect-Mediated Promotion of Mitophagy

**Yasuhiro Maejima** , Tokyo Medical and Dental Univ, Tokyo, Japan

1:30 PM

Board # 2256

Diacylglycerol Lipase Beta (daglβ) Deletion Attenuates Western Diet-induced Cardiac Inflammation, Oxidative Stress And Dysfunction

**Janos Paloczi** , Varga V Zoltan, Cody Savage, Holovac David, Csaba Matyas, Trojnar Eszter, Mukhopadhyay Partha, Natl Insts of Health, Rockville, MD; Mario van der Stelt, Leiden Inst of Chemistry, Leiden Univ, Leiden, Rockville, MD; Cravatt F. Benjamin, The Scripps Res Inst,, La Jolla,, CA; Pal Pacher, Natl Insts of Health, Rockville, MD

1:30 PM

Board # 2257

Differential ex vivo Stabilization of Transthyretin by AG10 and Tafamidis in Samples From Patients With Moderate or Severely Destabilizing Mutations

Paul W Wong, Alan X Ji, Eidos Therapeutics, San Francisco, CA; Jonathan Fox, Eidos Therapeutics Inc, San Francisco, CA; John L Berk, Boston Univ Sch of Med and Boston Medical Ctr, Boston, MA; **Uma Sinha** , Eidos Therapeutics Inc, San Francisco, CA

1:30 PM

Board # 2258

Effective Treatment of Diabetic Cardiomyopathy With a Selective Beta3-Adrenergic Receptor Antagonist, but Not Beta1-Adrenergic Receptor Blocker in a Murine Model

**Yixi Liu** , Heng-Jie Cheng, Zhe Chen, Leanne Groban, Dalane Kitzman, Donald A McClain, Che Ping Cheng, Wake Forest Sch of Med, Winston-Salem, NC

1:30 PM

Board # 2259

Effects of IL-1 Blockade With Anakinra on Blood Pressure, Systemic Vascular Resistance and Arterial Elastance in Patients With Heart Failure and Reduced Ejection Fraction: An Analysis of the Randomized, Double-blind, Placebo-controlled REDHART Study

**Leo F Buckley** , Brigham and Women's Hosp, Boston, MA; Justin M Canada, Cory R Trankle, Salvatore Carbone, Virginia Commonwealth Univ, Richmond, VA; Dinesh Kadariya, VCU Health System, Richmond, VA; Hayley Billingsley, VCU Health Systems, Richmond, VA; George Frank Wohlford IV, VCU Health System, Richmond, VA; Antonio Abbate, Virginia Commonwealth Univ, Richmond, VA; Benjamin W Van Tassell, Virginia Commonwealth Univ, Midlothian, VA

1:30 PM

Board # 2260

Histidyl Dipeptides Improves Contractile Function During Heart Failure by Enhancing Myosin ATPase Activity

**Jingjing Zhao** , Sujith Dassanayaka, David Hoetker, Kenneth Brittian, Univ of Louisville, Louisville, KY; Steven P Jones, Univ Louisville, Louisville, KY; Aruni Bhatnagar, Univ of Louisville, Louisville, KY; Shahid P Baba, Univ Louisville, Louisville, KY

1:30 PM

Poster Professor

Kenneth B Margulies, Philadelphia, PA

# Abstract Poster Session

## CH.APS.19 - Non-Congenital Pediatric Cardiology

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4153

Risk Factors for Heart Failure in Youth and Young Adults With Systemic Lupus Erythematosus

**Joyce C Chang** , Children's Hosp of Philadelphia, Philadelphia, PA; Rui Xiao, Univ of Pennsylvania, Philadelphia, PA; Stephen E Kimmel, Univ PA Sch Med, Philadelphia, PA; Laura A Mercer-Rosa, Children's Hosp of Philadelphia, Philadelphia, PA; Andrea M Knight, Hosp for Sick Children, Toronto, ON, Canada; Pamela F Weiss, Children's Hosp of Philadelphia, Philadelphia, PA

1:30 PM

Board # 4154

Cardiac Involvement in Classical or Hypermobile Ehlers-Danlos Syndrome is Uncommon

**Sharon Paige** , Kirstie Lechich, Elif Seda Selamet Tierney, Ronnie T Collins, Stanford Univ, Palo Alto, CA

1:30 PM

Board # 4155

Peripheral Arterial Stiffness Assessment Using Pulse Wave Doppler by Echocardiography in Healthy Children

**Yozo Teramachi** , Lisa K Hornberger, Sachie Shigemitsu, Nee K Khoo, Timothy Colen, Women's & Children Health Res Inst, Univ of Alberta, Edmonton, AB, Canada

1:30 PM

Board # 4156

Clinical Outcomes of Children With Rheumatic Heart Disease: A Retrospective Registry-Based Study in Uganda

**Meghan Zimmerman** , Children's Natl Health System, Washington, DC; Samalie Majorie Kitooleko, Emmy Okello, Uganda Heart Inst, Kampala, Uganda; Craig A Sable, Childrens Natl Medical Ctr, Potomac, MD; Andrea Z beaton, Cincinnati Childrens Hosp Medic, Cincinnati, OH; Chris Longenecker, Case Western Reserve Univ, Cleveland, OH; Peter Lwabi, Uganda Heart Inst, Kampala, Uganda

1:30 PM

Board # 4157

Cardiovascular Health of Preteen and Teenage Children of Diabetic Mothers: Evidence of Early Cardiovascular Programming

**Gayathri Wewala** , Victor Do, Lily Lin, Edmond Ryan, Luke Eckersley, Michael Stickland, Sandra Davidge, Lisa K Hornberger, Univ of Alberta, Edmonton, AB, Canada

1:30 PM

Board # 4158

Variation in Utilization of Pulmonary Vasodilators in Children and Adolescents With Pulmonary Hypertension: An Analysis of Data From the Marketscan Commercial and Medicaid Databases

**Michael L O'Byrne** , CHOP, Philadelphia, PA; Jen Faerber, Philadelphia, PA; Hannah Katcoff, David Frank, CHOP, Philadelphia, PA; Alexander Davidson, Therese M Giglia, CHOP, Philadelphia, PA; Catherine Avitabile, Philadelphia, PA

1:30 PM

Board # 4159

QTc Prolongation in Connective Tissue Disorders

**Burbuqe Ibrahimi** , Univ Hosp Zurich, Zurich, Switzerland; Roland Weber, Angela Oxenius, Pediatric Cardiology, Zurich, Switzerland; Matthias Greutmann, Congenital Heart Disease Ctr Univ Hosp Zurich, Zurich, Switzerland

1:30 PM

Board # 4161

The Reliability of the World Heart Federation Guidelines for the Echocardiographic Diagnosis of Rheumatic Heart Disease

**Andrea Z Beaton** , Cincinnati Childrens Hosp Medic, Washington, DC; Amy Scheel, Emory Univ Sch of Med, Atlanta, GA; Meghan Zimmerman, Children's Natl Health System, Washington, DC; Rachel Sarnacki, Children's Natl, Washington, DC; Mariana Mirabel, INSERM PARCC, Paris; Maria Do Carmo Pereira Nunes, UFMG, Belo Horizonte, Brazil; Andrew Steer, The Royal Children's Hosp, Melbourne, Melbourne, Australia; Emmy Okello, Uganda Heart Inst, Kampala, Uganda; Liesl Zuhlke, 2.17 Inst of Child Health Red, Cape Town, South Africa; Craig A Sable, Childrens Natl Medical Ctr, Potomac, MD

1:30 PM

Board # 4162

Bleeding Risk Associated With Thromboprophylaxis Combination Therapy is Low for Patients With Coronary Artery Aneurysms After Kawasaki Disease

**Tisiana Low** , The Hosp for Sick Children, Toronto, ON, Canada; Anusha Jegatheeswaran, Hosp for Sick Children, Toronto, ON, Canada; Paul Joseph Devlin, Hosp for Sick Children, Chicago, IL; Nita Chahal, The Hosp for Sick Children, Toronto, ON, Canada; Leonardo Brandao, Brian W McCrindle, Hosp for Sick Children, Toronto, ON, Canada

1:30 PM

Poster Professor

Jane W Newburger, Boston, MA

# Abstract Poster Session

## IM.APS.18 - Novel Approaches to Intravascular and Non-Invasive Imaging

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Chetan Shenoy, Minneapolis, MN

1:30 PM

Board # 4227

Poor Concordance Between Respiratory Variation in Inferior Vena Cava and Surrogates of Cardiac Output Measurements for Determination of Fluid Responsiveness

Isaac Laniado, Jee Young You, **Balaram Krishna J Hanumanthu** , Jorge-Bleik Ataucuri-Vargas,, Jacobi Medical Ctr, AECOM, Bronx, NY; Errold S Reid, NYU Winthrop Hosp, Mineola, NY; Harmeen Goraya, Univ of Arkansas for Medical Sciences, Little Rock, AR; Perminder Gulani, Jacobi Medical Ctr/Albert Einstein Coll of Med, Bronx, NY

1:30 PM

Board # 4228

Diagnostic Performance of Resting Full Cycle Ratio as Newly Developed Non Hyperemic Indices to Assess Functional Lesion Severity

**Hirofumi Ohashi** , Hiroaki Takashima, Akihiro Suzuki, Katsuhisa Waseda, Hirohiko Ando, Yusuke Nakano, Sakurai Shinichiro, Kazuhiro Naito, Hiroaki Sawada, Masanobu Fujimoto, Masahiro Shimoda, Atomu Tajima, Tetsuya Amano, Aichi Medical Univ, Nagakute, Japan

1:30 PM

Board # 4229

Data-Driven Approach for Coronary Vessel Reconstruction

**Kritika Iyer** , Univ of Michigan, Ann Arbor, MI; Christopher J Arthurs, King's Coll London, London, United Kingdom; Cyrus P Najarian, Reza Soroushmehr, Univ of Michigan, Ann Arbor, MI; Brahmajee Kartik Nallamothu, Univ Michigan Health System, Ann Arbor, MI; C. Alberto Figueroa, Univ of Michigan, Ann Arbor, MI

1:30 PM

Board # 4230

Characteristics and Clinical Impact of Healed Plaques in Patients With Acute Coronary Syndrome Optical Coherence Tomographic Evaluation

**Hitoshi Nakamura** , Ryu Syutta, Osaka Rosai Hosp, Sakai, Japan; Kyosuke Yanagawa, Osaka Rosai Hosp, Sakai-city, Japan; Yutaka Matsuhiro, Osaka Rousai Hosp, Sakai, Japan; Koji Yasumoto, Akihiro Tanaka, Naotaka Okamoto, Daisuke Nakamura, Yasuharu Matsunaga, Osaka Rosai Hosp, Sakai, Japan; Masamichi Yano, Kansai Rosai Hosp, Amgasaki, Japan; Masaki Yamato, Yasuyuki Egami, Osaka Rosai Hosp, Sakai, Japan; Masami Nishino, Osaka Rosai Hosp, Sakai Osaka, Japan; Jun Tanouchi, Osaka Rosai Hosp, Sakai, Osaka, Japan

1:30 PM

Board # 4231

Irregular Protrusion is Predictor for Development of Neoatherosclerosis After 2nd and 3rd Generation Drug-Eluting Stent Implantation - Optical Coherence Tomography Study

**Kyosuke Yanagawa** , Ryu Shutta, Yutaka Matsuhiro, Hitoshi Nakamura, Koji Yasumoto, Akihiro Tanaka, Naotaka Okamoto, Yasuharu Matsunaga, Daisuke Nakamura, Masamichi Yano, Masaki Yamato, Yasuyuki Egami, Jun Tanouchi, Masami Nishino, Osaka Rosai Hosp, Sakai, Japan

1:30 PM

Board # 4232

Coronary Plaque Characterization by Near-infrared Spectroscopy for Identification of Plaque Vulnerability: Association With Coronary Computed Tomographic Angiography

**Hideaki Ota** , Hiroyuki Omori, Toru Tanigaki, Tetsuo Hirata, Jun Kikuchi, Yoshihiro Sobue, Yoshiaki Kawase, Gifu Heart Ctr, Gifu, Japan; Munenori Okubo, Gifu heart center, Gifu, Japan; Hiroki Kamiya, Hitoshi Matsuo, Gifu Heart Ctr, Gifu, Japan

1:30 PM

Board # 4233

Association of Serum Xanthine Oxidoreductase Activity With Coronary Lipid-Core Plaques Evaluated by Near-Infrared Spectroscopy Intravascular Ultrasound in Patients With Stable Coronary Artery Disease

**Naoto Mori** , Chiba Univ, Chiba, Japan; Yuichi Saito, Chiba Univ Sch Of Med, Chiba, Japan; Hideki Kitahara, Yoshihide Fujimoto, Chiba Univ Hosp, Chiba, Japan; Yoshio Kobayashi, Chiba Univ, Chiba, Japan

1:30 PM

Board # 4235

Phenotypic Features of Coronary Atheroma in Hemodialysis-Dependent Patients With Coronary Artery Disease:Near-Infrared Spectroscopy and Intravascular Ultrasound Imaging Analysis

**Takamasa Iwai** , Natl Cerebral and Cardiovascular Ctr, Suita, Osaka, Japan; Yu Kataoka, Natl Cardiovascular Ctr, Suita, Japan; Hayato Hosoda, Natl Cerebral and Cardiovascular Ctr Hosp, Osaka, Japan; Kota Murai, Natl Cerebral and Cardiovascular Ctr, Suita, Osaka, Japan; Takahiro Nakashima, NCVC, Suita, Osaka, Japan; Satoshi Honda, Masashi Fujino, Natl Cerebral and Cardiovascular Ctr, Osaka, Japan; Kazuhiro Nakao, Natl Cardiovasculer Ctr, osaka, Japan; Shuichi Yoneda, Dokkyo Medical Univ, Tochigi, Japan; Fumiyuki Otsuka, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Kensaku Nishihira, Dept of Cardiology, Miyazaki Medical Association Hosp, Miyazaki, Japan, Miyazaki, Japan; Tomoaki Kanaya, Dokkyo Medical Univ Hosp, Tochigi, Japan; Yasuhide Asaumi, Teruo Noguchi, Natl Cerebral and Cardiovascular Ctr, Suita, Japan; Satoshi Yasuda, Natl Cereb Cardiovascular Ctr, Osaka, Japan

1:30 PM

Board # 4236

Direct Comparison of Resting Full-cycle Ratio With Fractional Flow Reserve in Physiological Assessment of Intermediate Coronary Artery Stenosis

**Tomohiro Honda** , Seiji Koga, Ryohei Akashi, Yuki Yamagata, Tsuyoshi Yonekura, Satoshi Ikeda, Hiroaki Kawano, Koji Maemura, Nagasaki Univ Hosp, Nagasaki, Japan

# Abstract Poster Session

## HF.APS.45 - Novel Diagnostic Approaches for Valvular Heart Disease

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2302

Prognostic Value of Automated Measurement of Mitral Annular Displacement by Speckle-tracking Echocardiography in Asymptomatic Aortic Stenosis Patients With Preserved Left Ventricular Ejection Fraction

**Takeshi Hozumi** , Ikuko Teraguchi, Kazushi Takemoto, Suwako Fujita, Teruaki Wada, Wakayama Medical Univ, Wakayama, Japan; Manabu Kashiwagi, Wakayama Medical Univ, Wakayama City, Japan; Kunihiro Shimamura, Yasutsugu Shiono, Akio Kuroi, Yoshiki Matsuo, Yasushi Ino, Takashi Kubo, Atsushi Tanaka, Takashi Akasaka, Wakayama Medical Univ, Wakayama, Japan

1:30 PM

Board # 2303

Handheld Wireless Digital Phonocardiography for Machine Learning-Based Detection of Mitral Regurgitation

**Brent E White** , Northwestern Memorial Hosp, Chicago, IL; Avi M Shapiro, Mia M Kanzawa, Subramaniam Venkatraman, Eko Devices, Inc., Berkeley, CA; Jason Paek, Northwestern Memorial Hosp, Chicago, IL; Steve Pham, John Maidens, Eko Devices, Inc., Berkeley, CA; James D Thomas, Patrick M McCarthy, Northwestern Memorial Hosp, Chicago, IL

1:30 PM

Board # 2304

Prognostic Value of NT-pro B-Type Natriuretic Peptide in Patients With Moderate Aortic Stenosis

**Saki Ito** , William Miranda, Vuyisile T Nkomo, Sorin Pislaru, Mayo Clinic, Rochester, MN; Patricia A Pellikka, Mayo Clinic Coll Med, Rochester, MN; Jae K Oh, Mayo Clinic, Rochester, MN

1:30 PM

Board # 2305

A Hybrid Convolutional and Recurrent Neural Network Architecture Accurately Detects Patients With Mitral Valve Prolapse From Echocardiography

**Shinichi Goto** , One Brave Idea/Brigham and Women's Hosp, Boston, MA; Francesca N Delling, Univ of California San Francisco, San Francisco, CA; Rahul C Deo, One Brave Idea/Brigham and Women's Hosp, Boston, MA

1:30 PM

Board # 2306

Higher Arterial Stiffness is Associated With Lower First-phase Ejection Fraction in Aortic Stenosis

**Eigir Einarsen** , Johannes J Hjertaas, Univ of Bergen, Bergen, Norway; Haotian Gu, Phil J Chowienczyk, King's Coll London, London, United Kingdom; John B Chambers, Guy's and St Thomas Hosp, London, United Kingdom; Knut Matre, Eva Gerdts, Univ of Bergen, Bergen, Norway; Sahrai Saeed, Haukeland Univ Hosp, Bergen, Norway

1:30 PM

Board # 2307

The Impact of Annular Eccentricity and Cover Index on Paravalvular Leak After Transcatheter Aortic Valve Replacement

**Anvi Raina** , Mohamad Hemu, Marie-France Poulin, Clifford J Kavinsky, Rush Univ Medical Ctr, Chicago, IL

1:30 PM

Board # 2308

Aortic Bioprosthetic Calcification Measured by Computed Tomography Predicts Long Term Survival and Reintervention Following Aortic Valve Replacement

**Bin Zhang** , Fuwai Hosp, CAMS, PUMC & Quebec Heart and Lung Inst, Quebec, QC, Canada; Audree Gilbert-Nadeau, Erwan Salaun, Quebec Heart and Lung Inst, Quebec, QC, Canada; Nancy Cote, CRIUCPQ, Quebec, QC, Canada; Haifa Mahjoub, Mathieu Patrick, Quebec Heart and Lung Inst, Quebec, QC, Canada; Philippe Pibarot, IUCPQ-UL, Quebec, QC, Canada; Marie Annick Clavel, Quebec Heart Inst, Quebec, QC, Canada

1:30 PM

Board # 2309

Relationships Between Bicuspid Aortic Valve Morphology and Hemodynamics: An Experimental Investigation of Flow, Leakage and Supra-Valvular Jet Using a Pulsatile Flow Circulation System and Magnetic Resonance Imaging

**Kaoru Hattori** , Tokyo Women's Medical Univ, Tokyo, Japan; Jumpei Takada, Ryo Kumazawa, Gohki Nishimura, Ryo Moriwaki, Natsuki Nakama, Eita Kawasaki, Waseda Univ, Tokyo, Japan; Michinobu Nagao, Yasuhiro Goto, Hiroshi Niinami, Tokyo Women's Medical Univ, Tokyo, Japan; Kiyotaka Iwasaki, Waseda Univ, Tokyo, Japan

1:30 PM

Board # 2310

A New Method for Instantaneous and Noninvasive Evaluation of Left Ventricular-Arterial Performance Following Transcatheter Aortic Valve Replacement

**Emad Mogadam** , Upstate Medical Universoty, Syracuse, NY; Gregory Giesler, Huntington Hosp, Pasadena, CA; Ray Matthews, Niema Pahlevn, Univ of Southern California, Los Angeles, CA

1:30 PM

Poster Professor

Judy Hung, Boston, MA

1:30 PM

Board # 2311

A Simple Method, Combining Brachial Pulse Wave Upstroke Time Components and Electrocardiographic Finding Provides High Diagnostic Accuracy of Aortic Valve Stenosis

**Masao Takahashi** , Jichi Medical Univ, Tochigi, Japan; Kyohei Fukatani, Fukuda Denshi Co Ltd, Tokyo, Japan; Tatsuya Yoneyama, Tetsuya Ito, Fukuda Denshi Co., Ltd, Tokyo, Japan; Tomoyuki Kabutoya, Jichi Medical Univ, Shimotsuke Tochigi, Japan; Satoshi Hoshide, Jichi Midical Univ, Shimotsuke, Japan; Kazuomi Kario, Jichi Medical Univ, Tochigi-Ken, Japan

1:30 PM

Board # 2312

Exercise Induced Pulmonary Capillary Wedge Pressure Elevation Impairs Lung Diffusion Capacity for Oxygen in Mitral Regurgitation

**Takayuki Hidaka** , Hiroshima Univ Hosp, Hiroshima, Japan; Hitoshi Susawa, Hiroshima Univ Graduate Sch of Med, Hiroshima, Japan; Kiho Itakura, Hiroshima Univ Hosp, Hiroshima, Japan; Yu Harada, Hiroshima Univ Graduate Sch of Biomedical and Health Sciences, Hiroshima, Japan; Hiroto Utsunomiya, Hiroshima Univ Hosp, Hiroshima, Japan; Kanako Izumi, Hiroshima Univ Graduate Sch of Biomedical and Health Sciences, Hiroshima, Japan; Mirai Kinoshita, Hiroshima Univ Hosp, Hiroshima, Japan; Yusuke Ueda, Yasuki Kihara, Hiroshima Univ Graduate Sch of Biomedical and Health Sciences, Hiroshima, Japan

# Abstract Poster Session

## AC.APS.13 - Novel Insights into Reducing Cardiovascular Risk

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4078

CRP Removal After Stemi Reduces Myocardial Damage: Results From the Cami1 Study

**Christoph Garlichs** , Wolfgang Ries, Diakonissenkrankenhaus Flensburg, Flensburg, Germany; Jan Torzewski, Cardiovascular Ctr Oberallg?u, Immenstadt, Germany; Christian Pfluecke, Heart Ctr Dresden Univ, Dresden, Germany; Harald Darius, Vivantes Neukoelln Medical Ctr, Berlin; Franz Heigl, MVZ Kempten, Kempten, Germany; Huseyin Ince, Steffen Mitzner, Uniklinik Rostock, Rostock, Germany; Peter Nordbeck, Univ Hosp Wuerzburg, Wuerzburg; Christian Butter, Herzzentrum Bernau, Bernau, Germany; Ahmed Sheriff, Charite Univsmedizin, Berlin, Germany

1:30 PM

Board # 4079

Efficacy and Safety of High Intensity Atorvastatin in Patients With Acute Myocardial Infartion Compared to High Intensity Rosuvastatin

Cheol Ung Choi, Cardiovascular Ctr, Seoul, Korea, Republic of; **Jah Yeon Choi** , Korea Univ Guro Hosp, Seoul, Korea, Republic of; Byoung Geol Choi, Cardiovascular Ctr, Seoul; Yoonjee Park, Korea Univ. Guro Hosp, Seoul; Dong Oh Kang, Won Young Jang, Woohyeun Kim, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Seung-young Roh, Dongguk Univ Medical Ctr, Goyang-si, Korea, Republic of; Jin Oh Na, Jin Won Kim, Eung Ju KIM, Seung Woon W Rha, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Chang Gyu Park, Korea Univ, Guro Hosp, Seoul, Korea, Republic of; Hong Seog Seo, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Myung Ho Jeong, Choannam Natl Univ Hosp, Gwangju, Korea, Republic of

1:30 PM

Board # 4080

ODYSSEY EAST - A Randomized, Double-blind, Parallel Group Study to Evaluate Alirocumab Efficacy and Safety Versus Ezetimibe In High-Risk Patients With Hypercholesterolemia on Maximally Tolerated Statin in China, India, and Thailand

**Yaling Han** , General Hosp of Shenyang Military Region, Shenyang, China; Jiyan Chen, Guangdong General Hosp, Guangdong, China; Vijaykumar Chopra, Medanta-The Medicity, Delhi, India; Shuyang Zhang, Peking Union Medical Coll Hosp, Bejing, China; Guohai Su, General Hosp of Shenyang Military Region, Jinan Central Hospital, China; Chang-Sheng Ma, Beijing Anzhen Hosp, Beijing, China; Zhouqing Huang, The First Affiliated Hosp of Wenzhou Medical Univ, Wenzhou, China; Yingyan Ma, General Hosp of Shenyang Military Region, Shenyang, China; Zhuhua Yao, Tianjin Union Medical Ctr, Tianjin, China; Zuyi Yuan, First Affliliated Med Coll of Xi An, Xi An; Qiang Zhao, Shanghai Jiaotong Univ Sch of Med, Shanghai, China; Srun Kuanprasert, Maharaj Nakorn Chiang Mai Hosp, Chiang Mai, Thailand; Marie T Baccara-Dinet, Sanofi, Montpellier, France; Garen Manvelian, Regeneron, Tarrytown, NY; Jianyong Li, Rui Chen, Sanofi, Shanghai, China

1:30 PM

Board # 4081

Glycemic Variability is a Strong Predictor in Patients With Impaired Glucose Tolerance After First Episode of Acute Coronary Syndrome

**Yohei Hanajima** , Noriaki Iwahashi, Jin Kirigaya, Hironori Takahashi, Yokohama City Univ Medical Ctr, Yokohama, Japan; Yugo Minamimoto, Yokohama City Univ, Yokohama, Japan; Eiichi Akiyama, Yokohama City Univ Medical Ctr, Yokohama, Japan; Kozo Okada, Yokohama City Univ Med Ctr, Yokohama, Japan; Nobuhiko Maejima, Yokohama City Univ Medical Ctr, Yokohama, Japan; Yasushi Matsuzawa, Yokohama City Univ, Yokohama, Japan; Kiyoshi Hibi, Yokohama, Yokohama, Japan; Masami Kosuge, Toshiaki Ebina, Yokohama City Univ Medical Ctr, Yokohama, Japan; Kouichi Tamura, Yokohama City Univ Sch of Med, Yokohama, Japan; Kazuo Kimura, Yokohama City Univ Medical Ce, Yokohama, Japan

1:30 PM

Board # 4082

The Impact of Perivascular Epicardial Adipose Tissue Thickness on 1-Year Composite Major Adverse Cardiac Events After ST-Segment Elevation Myocardial Infarction

Takumi Toya, Michel Corban, John Bois, Lilach O Lerman, **Amir Lerman** , Mayo Clinic, Rochester, MN

1:30 PM

Board # 4083

Influence of Diabetes Mellitus on Long-Term Outcomes of Staged Percutaneous Coronary Intervention for Patients With ST-Segment Elevation Myocardial Infarction and Multivessel Coronary Artery Disease

**Kongyong Cui** , Min Zhang, Feng Xu, Fei Yuan, Xiantao Song, Hong Liu, Shuzheng Lyu, Beijing Anzhen Hosp, Capital Medical Univ and Beijing Inst of Heart, Lung and Blood Vessel Diseases, Beijing, China

1:30 PM

Board # 4084

Inflammation and Diabetes Mellitus in Acute Myocardial Infarction. Are They Risk Equivalent of Short-Term and Long-Term Prognosis?

**Nicola Cosentino** , Stefano Genovese, Jeness Campodonico, Filomena Pacelli, Maria Luisa Biondi, Maurizio Rondinelli, Ctr Cardiologico Monzino, Milan, Italy; Alice Bonomi, Ctr Cardiologico Monzino, Milano, Italy; Valentina Milazzo, Ctr Cardiologico Monzino, Milan, Italy; Monica de Metrio, Ctr Cardiologico Monzino, Milano, Italy; Katia Celentano, Marco Moltrasio, Claudia Lucci, Mara Rubino, Ctr Cardiologico Monzino, Milan, Italy; Giancarlo Marenzi, Ctr Cardiologico Monzino, IRCCS, Milan, Italy

1:30 PM

Board # 4085

Impact of Socioeconomic Status on 30-Day Readmission Risk in Young Patients With First Acute Myocardial Infarction: A Population-Based Cohort Study

Mohamed M Gad, Cleveland Clinic, Cleveland, Ohio, OH; **Anas M Saad** , Cleveland Clinic, Cleveland, OH; Keerat Rai Ahuja, Cleveland Clinic, Cleveland, Ohio, OH; Najdat Bazarbashi, Cleveland Clinic, Cleveland, OH; Antonette Karrthik, Cleveland Clinic, Cleveland, OH, Cleveland, OH; Manpreet Kaur, Simrat Kaur, Cleveland Clinic, Cleveland, OH; Yasser Sammour, Cleveland, OH; Johnny Chahine, Cleveland Clinic Fairview Hosp, Cleveland, OH; Amer Kadri, Beaumont Health, Dearborn, MI; Samir R kapadia, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 4086

Disparities in Care and Outcomes Among Homeless Adults Hospitalized for Acute Myocardial Infarction, Cardiac Arrest, and Stroke

**Rishi Wadhera** , Eunhee Choi, Changyu Shen, Beth Israel Deaconess Medical Ctr, Harvard Medical Sch, Boston, MA; Robert W Yeh, Beth Israel Deaconess Med Ctr, Boston, MA; Karen E Joynt Maddox, Washington Univ Sch of Med, Saint Louis, MO

1:30 PM

Board # 4087

Improvement in Left Ventricular Performance With Anakinra in St-Segment Elevation Myocardial Infarction

Cory R Trankle, Virginia Commonwealth Univ, Richmond, VA; Dinesh Kadariya, VCU, Richmond, VA; Marco Giuseppe Del Buono, **Leo F Buckley** , Horacio Medina de Chazal, VCU, Glen Allen, VA; Juan Guido Chiabrando, Hosp Italiano de Buenos Aires, Buenos Aires, Argentina; Maria M Abraham Foscolo, VCU, Glen Allen, VA; George Frank Wohlford IV, VCU Health System, Richmond, VA; Salvatore Carbone, Virginia Commonwealth Univ, Richmond, VA; Nayef Abouzaki, Jeremy Turlington, VCU, Glen Allen, VA; Roshanak Markley, VCU, Richmond, VA; Benjamin W Van Tassell, Virginia Commonwealth Univ, Midlothian, VA; Antonio Abbate, VCU, Glen Allen, VA

1:30 PM

Poster Professor

neha Pagidipati

1:30 PM

Board # 4088

Dysregulation of Angiomirs in Coronary Artery Disease Patients: Effects on Vegf Pathway

**Larissa Ferreira-Santos** , Insto do Coração do Hosp das Clínicas da Faculdade de Medicina da Univ de São Paulo (InCor /HCFMUSP), Sao Paulo, Brazil; Edilamar M. Oliveira, Sch of Physical Education and Sport - Univ of Sao Paulo, Sao Pulo, Brazil; João L. P. Gomes, Tiago Fernandes, Sch of Physical Education and Sport - Univ of Sao Paulo, Sao Paulo, Brazil; Carlos A. Nascimento Filho, Insto do Coração do Hosp das Clínicas da Faculdade de Medicina da Univ de São Paulo (InCor /HCFMUSP), Sao Paulo, Brazil; Verônica O. Lopes, Sch of Physical Education and Sport - Univ of Sao Paulo, Sao Paulo, Brazil; Graziela Amaro-Vicente, Jaquelline M. Jardim, Maria Janieire N. Alves, Patricia A. Oliveira, Luiz A. M. César, Carlos E. Negrão, Insto do Coração do Hosp das Clínicas da Faculdade de Medicina da Univ de São Paulo (InCor /HCFMUSP), Sao Paulo, Brazil; Maria Urbana P. B. Rondon, Sch of Physical Education and Sport - Univ of Sao Paulo, Sao Paulo, Brazil

# Abstract Poster Session

## EP.APS.29 - Obesity, Cardiometabolic Disorders and CVD risk

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3061

Low Levels of Hemoglobin A1c Are Associated With Higher Cardiovascular Mortality in a General Population Without Medication for Diabetes

Hisako Tsuji, Hlth Examiation Ctr of Moriguchi City, Moriguchi, Osaka, Japan; **Hiroyuki Sueyoshi** , Yuzo Akita, Osaka Saiseikai Izuo Hosp, Osaka, Japan; Ichiro Shiojima, Kansai Mdeical Univ, Hirakata, Japan

1:30 PM

Board # 3062

Weight Loss and Type 2 Diabetes Are Mutually Independent Predictors of Mortality in Patients With Established Coronary Artery Disease

**Christoph H Saely** , Private Univ of the Principality of Liechtenstein, Triesen, Liechtenstein; Alexander Vonbank, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Christine Heinzle, Daniela Zanolin-Purin, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; Arthur Mader, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Abdurahman Said, Private Univ of the Principality of Liechtenstein, Triesen, Liechtenstein; Andreas Leiherer, Axel Muendlein, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; Heinz Drexel, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland

1:30 PM

Board # 3063

Serum Ceramide Ratios Predict Cardiovascular Events in Patients With Type 2 Diabetes Independently From the Presence of Coronary Artery Disease

Andreas Leiherer, Axel Muendlein, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; **Christoph H Saely** , Private Univ of the Principality of Liechtenstein, Triesen, Liechtenstein; Reijo Laaksonen, Mitja Lääperi, Zora Biosciences, Espoo, Finland; Alexander Vonbank, Arthur Mader, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Peter Fraunberger, Medical Central Labs, Feldkirch, Austria; Heinz Drexel, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland

1:30 PM

Board # 3064

The Ceramide-based Coronary Event Risk Test (CERT) Predicts Cardiovascular Mortality in Cardiovascular Disease Patients With Type 2 Diabetes Mellitus as Well as in Those Without Diabetes

Andreas Leiherer, Axel Muendlein, Vorarlberg Inst for Vascular Investigation & Treatment (VIVIT), Feldkirch, Austria; **Christoph H Saely** , Private Univ of the Principality of Liechtenstein, Triesen, Liechtenstein; Reijo Laaksonen, Mitja Lääperi, Zora Biosciences, Espoo, Finland; Alexander Vonbank, Arthur Mader, Academic Teaching Hosp Feldkirch, Feldkirch, Austria; Iris Baumgartner, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland; Peter Fraunberger, Medical Central Labs, Feldkirch, Austria; Heinz Drexel, Swiss Cardiovascular Ctr, Univ Hosp Bern, Bern, Switzerland

1:30 PM

Board # 3065

Association Between Obesity and Atrial Fibrillation in Type 2 Diabetes Mellitus: Post Hoc Analysis of the ACCORD Trial

**Brian Laughey** , Wake Forest Sch of Med, Winston-Salem, NC; Matthew J Singleton, Prashant Bhave, Elsayed Z Soliman, Joseph Yeboah, Wake Forest Sch of Med, Winston Salem, NC

1:30 PM

Board # 3067

Association of Impaired Glucose Tolerance With Silent Myocardial Infarction and Their Relationship With Mortality

**Muhammadimtiaz Ahmad** , Tokir Mujtaba, Wake Forest Sch of Med, Winston Salem, NC; Muhammad Ali Anees, Allama Iqbal Medical Coll, Lahore, Pakistan; Sanjay Kumar Maheshwari, Liaquat Univ of Medical and Health Sciences, Jamshoro, Pakistan; Elsayed Z Soliman, Wake Forest Sch of Med, Winston Salem, NC

1:30 PM

Board # 3068

Prevalence and Associated Metabolic Factors of Non-alcoholic Fatty Liver Disease in Acute Stroke Patients Aged 40-79 Years

**Takahisa Mori** , Shonan Kamakura General Hosp Stroke Ctr, Kamakura, Japan; Kazuhiro Yoshioka, Shonan Kamakura General Hosp, Kamakura, Kanagawa, Japan

1:30 PM

Board # 3069

High-Sensitivity C-reactive Protein is a Significantly Associated With the Advanced Atherosclerosis, but Not With the Presence of Atherosclerosis in General Male Population

**Satoko Ojima** , Takuro Kubozono, Shin Kawasoe, Takeko Kawabata, Masaaki Miyata, Graduate Sch of Medical and Dental Sciences, Kagoshima Univ, Kagoshima, Japan; Hironori Miyahara, Shigeho Maenohara, Kagoshima Kouseiren, Kagoshima, Japan; Mitsuru Ohishi, Graduate Sch of Medical and Dental Sciences, Kagoshima Univ, Kagoshima, Japan

1:30 PM

Board # 3070

Impact of Hyperuricemia on Mortality Related to Aortic Diseases

Yoichiro Otaki, Yamagata Univ, Yamagata, Japan; **Tetsu Watanabe** , Tsuneo Konta, Masafumi Watanabe, Yamagata Univ Sch of Med, Yamagata, Japan; Steering Committee of Research on Design of the Comprehensive Health Care System for Chronic Kidney

1:30 PM

Poster Professor

Roberta Florido, Baltimore, MD

# Abstract Poster Session

## AC.APS.14 - Optimizing Care for the Most Vulnerable

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Jacob C Jentzer, Rochester, MN

1:30 PM

Board # 4089

ST-Elevation Myocardial Infarction Among Patients With End Stage Renal Disease. A Contemporary Analysis of the National Inpatient Sample Database

**Moinuddin Syed** , Cook County Health, Chicago, IL; Marwan Abougergi, Univ of South Carolina, Columbia, SC; Pedro A Villablanca, Henry Ford Hosp, Detroit, MI; Neha Yadav, Cook County Health, Chicago, IL

1:30 PM

Board # 4090

Prognostic Significance of Left Ventricular Systolic Dysfunction at the Time of NSTEMI in Patients With No Prior History of Heart Failure

**David D Berg** , Brigham and Women's Hosp, Boston, MA; Michelle L Odonoghue, Brigham Womens Hosp, Boston, MA; Jianping Guo, Christopher P Cannon, David A Morrow, Robert P Giugliano, Brigham and Women's Hosp, Boston, MA; Philippe Gabriel Steg, Hop Bichat, Paris, France; Stephen D Wiviott, Brigham and Womens Hosp, Boston, MA; Eugene Braunwald, Marc S Sabatine, Brigham and Women's Hosp, Boston, MA

1:30 PM

Board # 4091

Outcomes With Timing of In-hospital Cardiac Arrest Complicating St-elevation Myocardial Infarction Receiving Primary Percutaneous Coronary Intervention

**Saraschandra Vallabhajosyula** , Saarwaani Vallabhajosyula, Malcolm R Bell, Abhiram Prasad, Mandeep Singh, Roger D White, Allan S Jaffe, David R Holmes Jr., Jacob C Jentzer, Mayo Clinic, Rochester, MN

1:30 PM

Board # 4092

Seasonal Variation Among Acute Coronary Syndrome Patients in the United States; Patient Characteristic, Hospital Admissions, and In-Hospital Outcomes

Adebayo C Atanda, George Washington Univ Hosp, Washington DC, DC; **Olajide Buhari** , Jacobi Medical Ctr, Bronx, NY; Talal Alzharani, George Washington Univ Hosp, Washington DC, DC; Sakiru Isa, Trowbridge Rd, East Lansing, Lansing, MI; Olusayo Fadiran, Howard Univ Hosp, Washington, DC; Joseph Forgione, George Washington Univ Hosp, Washington, DC; Oluwafunmilayo Atanda, Howard Univ Hosp, Washington DC, DC; Christian Nagy, GWUH, Washington, DC; Ramesh Mazhari, Jonathan Samuel Reiner, George Washington Univ, Washington, DC; Joseph Krepp, The George Washington Univ, Washington, DC

1:30 PM

Board # 4093

Ten-year Trends in Prevalence and One-year Mortality of Cardiogenic Shock in Acute Myocardial Infarction. The Fast-mi Programme 2005-2015

Nadia Aissaoui, Hosp Europeen Georges Pompidou, Paris, France; Etienne Puymirat, Hop Europ?en Georges Pompid, Paris; Edouard Gerbaud, Hosp Haut Leveque, Pessac, France; Nicolas Lamblin, Hop Cardiologique, CHRU, Lille, France; Hakim Benamer, Inst Cardiovasculaire Paris Sud, Massy, France; Jean Ferrieres, Hop Rangueil, Toulouse, France; Francois Schiele, Hop Jean Minjoz, Besancon, France; Tabassome Simon, Hop St Antoine, Paris, France; **Nicolas Danchin** , Hosp Europeen Georges Pompidou, Paris, France; for the FAST-MI investigators

1:30 PM

Board # 4094

Difference of Prognostic Impact of Hemodialysis Patients With or Without ACS

**Akihiro Takasaki** , Tairo Kurita, Yousuke Hirabayashi, Mie Univ Hosp, Tsu, Japan; Akiko Tanoue, Murase Hosp, Suzuka, Japan; Takashi Yamanaka, Yokkaichi Hazu Medical Ctr, Yokkaichi, Japan; Jun Masuda, Mie Prefectual General Hosp, Yokkaichi, Japan; Hirofumi Machida, Takeuchi Hosp, Tsu, Japan; Takehiko Ichikawa, Kuwana City Medical Ctr, Kuwana, Japan; Masaaki Ito, Mie Univ Graduate Sch of Med, Tsu-shi, Japan; Kaoru Dohi, Mie Univ Graduate Sch of Med, Tsu, Japan

1:30 PM

Board # 4095

Myocardial Left Ventricular Mechanical Uniformity Alterations and Adverse Cardiac Events Following Myocardial Infarction

Thomas Stiermaier, Univ Med Göttingen, Lübeck, Germany; Sören J. Backhaus, Torben Lange, Alexander Koschalka, Jenny-Lou Navarra, Patricia Boom, Univ Med Göttingen, Goettingen, Germany; Pablo Lamata, KCL, London, United Kingdom; Johannes Kowallick, Univ Medical Ctr Göttingen, Goettingen; Joachim Lotz, Univ Med Göttingen, Goettingen, Germany; Gerd Hasenfuss, Univsmedizin Gottingen, Goettingen, Germany; Matthias Gutberlet, Heart Ctr Leipzig, Univ of Leipzig, Inst of Diagnostic and Interventional Radiology, Leipzig, Germany, leipzig, Germany; Suzanne de Waha-Thiele, Univ Med Luebeck, Lübeck, Germany; Steffen Desch, Heart Ctr Leipzig, Univ of Leipzig, Dept of Cardiology, Leipzig, Germany, Leipzig, Germany; Holger Thiele, Univ Leipzig - Heart Ctr, Leipzig; Ingo Eitel, Univ Med Luebeck, Lübeck, Germany; **Andreas Schuster** , Univ Med Göttingen, Goettingen, Germany

1:30 PM

Board # 4096

Frailty Associated With Increased Bleeding in Elderly With Acute Myocardial Infarction : A Systematic Review and Meta-analysis

**Prapaipan Putthapiban** , Einstein Medical Ctr, Philadelphia, PA; Wasawat Vutthikraivit, Texas Tech Univ, Lubbock, TX; Weera Sukhumthammarat, Einstein Medical Ctr, Philadelphia, PA; Pattara Rattanawong, Univ of Hawaii Internal Med Residency Program, Honolulu, HI; Napatt Kanjanahattakij, Einstein Medical Ctr, Philadelphia, PA; Aman Amanullah, Albert Einstein Medical Ctr, Philadelphia, PA

1:30 PM

Board # 4098

Family History vs. Modifiable Risk Factors for Determining Long Term Prognosis Among Adults Who Experience Myocardial Infarction at a Young Age: The Partners Young MI Registry

**David Biery** , Brigham and Women's Hosp, Boston, MA; Avinainder Singh, Yale-New Haven Hosp, New Haven, CT; Sanjay Divakaran, Junjie Yang, Adam Berman, Brigham and Women's Hosp, Boston, MA; Ersilia M Defilippis, NYP/Columbia Univ Medical Ctr, New York, NY; Josh Klein, Jon Hainer, Brigham and Women's Hosp, Boston, MA; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD; James L Januzzi, Massachusetts General Hosp, Wellesley Hills, MA; Pradeep Natarajan, Massachusetts General Hosp, Boston, MA; Khurram Nasir, Baptist Health South Florida, New Haven, CT; Marcelo F Di Carli, Deepak L Bhatt, Ron Blankstein, Brigham and Womens Hosp, Boston, MA

# Abstract Poster Session

## HF.APS.42 - Pre-Clinical Assessment of Pharmacological Therapy for Heart Failure

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2272

Chronic Metformin Treatment Restores Mitochondrial Function in Aged Heart and Decreases Subsequent Ischemia-Reperfusion Injury

**Qun Chen** , Jeremy Thompson, Ying Hu, VCU, Richmond, VA; Edward Joseph Lesnefsky, Virginia Commonwealth Univ, Richmond, VA

1:30 PM

Board # 2273

A Larval Zebrafish Model of Cardiac Physiological Recovery Following Myocardial Hypoxia Enables Evaluation of the Time Course and Efficacy of Pharmacological Treatments

Regina Abramova, Naim Bautista, Univ of North Texas, Denton, TX; Regina Fritsche Danielson, AstraZeneca, Gothenburg, Sweden; Avi Gupta, Univ of North Texas, Denton, TX; Kenny Hansson, AstraZeneca, Gothenburg, Sweden; Neha Iyer, Pudur Jagadeeswaran, Univ of North Texas, Denton, TX; Karin Jennbacken, AstraZeneca, Gothenburg, Sweden; Vishal Patel, Revathi Raman, Univ of North Texas, Denton, TX; Qing-Dong Wang, AstraZeneca, Gothenburg, Sweden; **Warren Burggren** , Univ of North Texas, Denton, TX

1:30 PM

Board # 2274

Intramyocardial Injections of Nanoparticles Loaded With Hepatic Growth Factor and Insulin-Like Growth Factor-1 Improve Contractile Function and Reduce Infarct Size in a Porcine Model of Myocardial Ischemia Reperfusion Injury

**Ming Wu** , Piet Claus, KU Leuven, Leuven, Belgium; Stijn De Buck, Univ Hosp Leuven, Leuven, Belgium; Denise Veltman, Hilde Gillijns, Holemans Patricia, KU Leuven, Leuven, Belgium; Peter Pokreisz, CoBioRes NV, Leuven, Belgium; Ellen Caluwé, KU Leuven, Leuven, Belgium; Estefania I Colino, Univ of Navarra, Pamplona, Spain; Smadar Cohen, Ben-Gurion Univ of the Negev, Beer Sheva, Israel; Felipe Prosper, Beatriz Pelacho, Univ of Navarra, Pamplona, Spain; Stefan P Janssens, Univ Hosp Leuven, KU Leuven, Leuven, Belgium

1:30 PM

Board # 2275

Pyridostigmine Enhances Cardiomyocyte Calcium Handling and Reduces Arrhythmogenic Calcium Waves in a Transverse Aortic Constriction Model of Heart Failure

**Stephen H Baine** , The Ohio State Univ, Columbus, OH; Andriy Belevych, Ohio State Univ, Columbus, OH; Ingrid M Bonilla, The Ohio State Univ, Columbus, OH; Cynthia A Carnes, Sandor Gyorke, Ohio State Univ, Columbus, OH

1:30 PM

Board # 2276

**Beta** 3 **-Adrenergic-Receptor-Deficient Mice Protected From Diabetes-Induced Cardiomyopathy: Pivotal Role of the Prevention of Cardiac CaMKII Upregulation**

**Heng-Jie Cheng** , Zhe Chen, Yixi Liu, Xiaowei Zhang, Donald A McClain, Wake Forest Sch of Med, Winston-Salem, NC; Dalane Kitzman, Wake Forest Sch of Med, Winston Salem, NC; Che Ping Cheng, Wake Forest Sch of Med, Winston-Salem, NC

1:30 PM

Board # 2277

The Cardiorenal Effects of Chronic Phosphodiesterase V Inhibition in Preclinical Systolic Dysfunction

**Scott Hubers** , Siu-Hin Wan, Paul M McKie, Christopher Scott, Horng Chen, Mayo Clinic, Rochester, MN

1:30 PM

Board # 2278

Clinical Assessment of AT-001, an Aldose Reductase Inhibitor in Development for Diabetic Cardiomyopathy: A 28-Day Proof of Concept Study

**Riccardo Perfetti** , Shoshana Shendelman, Applied Therapeutics, New York, NY

1:30 PM

Board # 2279

Oral Administration of Synthetic Prostacyclin Agonist ONO-1301 Improves Survival Rate With Prevention in Deteriorated Pathophysiology of Dilated Cardiomyopathy Model Hamsters

**Naoki Okuda** , Shigeru Miyagawa, Osaka Univ, Suita, Japan; Takuji Kawamura, Akima Harada, Osaka Univ, Osaka, Japan; Yoshiki Sakai, Osaka, Japan; Takayoshi Ueno, Osaka, Japan, Suita, Osaka, Japan; Yoshiki Sawa, Osaka Univ, Osaka, Japan

1:30 PM

Board # 2280

Activation of the Growth Hormone-Releasing Hormone Receptor Prevents the Development of Heart Failure With Preserved Ejection Fraction in CD1 Mice

**Raul A Dulce** , Univ of Miami Miller Sch of Med, Miami, FL; Rosemeire M Kanashiro-Takeuchi, Univ of Miami, Miami, FL; Lauro M Takeuchi, Univ of Miami Miller Sch of Med, Miami, FL; Alessandro Salerno, Univ of Miami, Miami, FL; Wayne Balkan, Univ Miami Miller Sch, Miami, FL; Shathiyah Kulandavelu, Univ of Miami Miller Sch of Med, Miami, FL; Renzhi Cai, Veteran Affairs Medical Ctr, Miami, FL; Andrew V Schally, Univ of Miami Miller Sch of Med, Miami, FL; Joshua M Hare, Univ of Miami, Miami, FL

# Abstract Poster Session

## EA.APS.32 - Predicting and Improving Arial Fibrillation Ablation Outcomes

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Bryan Baranowski

1:30 PM

Board # 2094

Heparin and Low-molecular-weight Heparin Switch Associated With an Increase in Bleeding Complications in Patients on Apixaban Undergoing Catheter Ablation: The Amper Ablation Study

**Walid Amara** , Hosp intercommunal Raincy, Montfermeil, France; Rodrigue Garcia, Hosp of Poitiers, Poitiers, France; Jacques Mansourati, Hop La Cavale Blanche, Brest Cedex 2, France; Jérome Taieb, Hosp of Aix en Provence, Aix en Provence, France; Estelle Gandjbackh, CHU Pitie-Salpetriere, Paris, France; Antoine Dompnier, Hosp of Annecy, Annecy, France; Herve Gorka, Hosp of Louis Pasteur, Chartres, France; Noura Zannad, Regional Hosp of Metz-Thionville, Thionville, France; Antoine Da Costa, Hosp of Saint-Etienne, Saint-Etienne, France; Frédéric Sacher, Hosp of Haut Leveque, Pessac, France; François Jourda, Hosp of Auxerre, Auxerre, France; Stephane Fromentin, Hosp of Belfort-Montbeliard, Montbéliard, France; Saida Cheggour, Hosp of Avignon, Avignon, France; Frédéric Georger, Hosp of Béziers, Béziers, France; Antoine Milhem, Hosp of La Rochelle, La Rochelle, France

1:30 PM

Board # 2095

Association Between Atrial Fibrillation Type and Healthcare Utilization Outcomes Among Patients Undergoing Catheter-Based Atrial Fibrillation Ablation: Insights From a Population-Based Registry in Ontario, Canada

**Andrew C Ha** , Peter Munk Cardiac Ctr, Toronto, ON, Canada; Harindra C Wijeysundera, Sunnybrook Health Sciences Ctr, Toronto, ON, Canada; Feng Qiu, Kayley Henning, ICES, Toronto, ON, Canada; Kamran Ahmad, Paul Angaran, St. Michael's Hosp, Toronto, ON, Canada; David H Birnie, Univ of Ottawa Heart Inst, Ottawa, ON, Canada; Eugene Crystal, Sunnybrook Health Sciences Ctr, Toronto, ON, Canada; Jeff S Healey, McMaster Univ, Hamilton, ON, Canada; Andrew Hongil Ha, Trillium Health Partners, Mississauaga, ON, Canada; Peter Leong-Sit, London Health Sciences Ctr, Toronto, ON, Canada; Bhavanesh Makanjee, Scarborough Health Network, Toronto, ON, Canada; Pablo Nery, Univ of Ottawa Heart Inst, Ottawa, ON, Canada; Damian Paul Redfearn, London Health Sciences, London, ON, Canada; Allan Skanes, Univ Hosp, London, ON, Canada; Atul Verma, Southlake Regional Health Ctr, Newmarket, ON, Canada

1:30 PM

Board # 2097

Pain at the Puncture Site and Back Pain in Patients Undergoing Electrophysiology Procedures With Venous Access Site Closure Utilizing Vascular Closure Device vs Manual Compression

**Sanghamitra Mohanty** , Chintan G Trivedi, Amin Al-Ahmad, Rodney Paul Horton, Domenico Giovanni Della Rocca, Carola Gianni, Bryan MacDonald, Ugur Canpolat, Texas Cardiac Arrhythmia Inst, Austin, TX; Luigi Di Biase, 400 Central Park West Apt 9G, New York, NY; Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

1:30 PM

Board # 2098

Uninterrupted vs. Interrupted Dabigatran. Uninterrupted Dabigatran is Associated With Optimal Act Control During Catheter Ablation

**Shunsuke Miyauchi** , Yukiko Nakano, Yoshihiro Ikeuchi, Sho Okamura, Yosaku Okubo, Naoya Hironobe, Takehito Tokuyama, Yasuki Kihara, Graduate Sch of Biomedical Sciences, Hiroshima Univ, Hiroshima, Japan

1:30 PM

Board # 2099

New Evidence of Significant Incremental Benefit of Uninterrupted Direct Oral Anticoagulants vs. Uninterrupted Vitamin K Antagonists During Catheter Ablation of Atrial Fibrillation: A Systematic Review and Meta-analysis of Randomized Controlled Trials

**Roberto C Cerrud-Rodriguez** , Jorge Romero, Juan Carlos Diaz, Priscilla Lajara-Hallal, Daniel Rodriguez, Jose Taveras, Samiullah Arshad, Milton Sandoval, Isabella M Alviz, Luis Cerna, Vito Grupposo, Montefiore Medical Ctr, Bronx, NY; Andrea Natale, St. David's Medical Ctr, Austin, TX; Mario J Garcia, Luigi Di Biase, Montefiore Medical Ctr, Bronx, NY

1:30 PM

Board # 2100

Best Ablation Strategy in Patients With Coexistent Metabolic Syndrome and Long-Standing Persistent Atrial Fibrillation: Results From a Propensity-Matched Population

**Sanghamitra Mohanty** , Chintan Gautambhai Trivedi, Domenico Giovanni Della Rocca, Carola Gianni, Texas Cardiac Arrhythmia Inst, Austin, TX; Ugur Canpolat, Hacettepe Univ, Ankara, Turkey; Bryan MacDonald, John David Burkhardt, Javier Sanchez, Texas Cardiac Arrhythmia Inst, Austin, TX; Patrick Hranitzky, Texas Cardiac Arrhythmia Inst, Hillsborough, NC; G Gallinghouse, Amin Al-ahmad, Rodney Paul Horton, Mohammed Bassiouny, Texas Cardiac Arrhythmia Inst, Austin, TX; Luigi Di Biase Sr., Albert Einstein Coll of Med, New York, NY; Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

1:30 PM

Board # 2101

Sex Differences in Cardiovascular Risk Reduction With Catheter Ablation for Atrial Fibrillation

**Xiaoxi Yao** , Bernard Gersh, Nilay Shah, Peter Noseworthy, Mayo Clinic, Rochester, MN

1:30 PM

Board # 2102

Impact of Gender on Atrial Fibrillation Recurrence After Catheter Ablation: A Meta-Analysis of Large Cohort Studies (>1,000 Patients)

**M Rubayat Rahman** , Texas Tech Univ, Lubbock, TX; Mohamed Elmassry, Texas Tech Univ Health S C, Lubbock, TX; Pablo Paz, Texas Tech Univ, Lubbock, TX; Saif El Nawaa, Texas Tech Univ HSC, Lubbock, TX; Barbara Mantilla, TBD, Lubbock, TX; Wasawat Vutthikraivit, Texas Tech Health Sciences Ctr, Lubbock, TX; Pattara Rattanawong, Univ of Hawaii, Honolulu, HI; Prapaipan Putthapiban, Einstein Medical Ctr, Philadelphia, PA; Mohammad Mehdi Ansari, Scott W Shurmur, Texas Tech Univ, Lubbock, TX

1:30 PM

Board # 2103

Correlation of Body Mass Index With Ablation Outcome and Comorbidities in Patients With Atrial Fibrillation

**Sanghamitra Mohanty** , Chintan G Trivedi, Texas Cardiac Arrhythmia Inst, Austin, TX; Veronica Natale, Johns Hopkins Bloomberg, Baltimore, MD; Rong Bai, Beijing Anzhen Hosp, Beijing, TX; Joanna Assadourian, U of Texas at Austin, Austin, TX; Domenico Giovanni Della Rocca, Carola Gianni, Texas Cardiac Arrhythmia Inst, Austin, TX; Pamela Horton, St. Edwards Univ, Austin, TX; Bryan MacDonald, John David Burkhardt, Javier Sanchez, Joe Gallinghouse, Amin Al-Ahmad, Rodney Paul Horton, Andrea Natale, Texas Cardiac Arrhythmia Inst, Austin, TX

1:30 PM

Board # 2104

First-Pass Isolation is Associated With Durability of Pulmonary Vein Isolation and Has Impact on Atrial Fibrillation Ablation Outcomes

**Yuichi Ninomiya** , Kagoshima Univ, Kagoshima, Japan; Koichi Inoue, Sakurabashi Watanabe Hosp, Osaka, Japan; Hitoshi Ichiki, Dept of Cardiovascular Med and Hypertension, Kagoshima Univ, Kagoshima, Japan; Yasuhisa Iriki, Kagoshima Univ, Kagoshima, Japan; Koji Tanaka, Sakaurabashi Watanabe Hosp, Osaka, Japan; Toshinari Onishi, Yuko Hirao, Takafumi Oka, Nobuaki Tanaka, Masato Okada, Hiroyuki Inoue, Yasushi Koyama, Atsunori Okamura, Sakurabashi Watanabe Hosp, Osaka, Japan; Katsuomi Iwakura, Sakurabashi Waturahe Hosp, Osaka, Japan; Kenshi Fujii, Sakurabashi Watanabe Hosp, Osaka, Japan; Mitsuru Ohishi, Kagoshima Univ, Kagoshima, Japan

1:30 PM

Board # 2105

Association of Electroanatomic Mapping Derived Left Atrial Bipolar Voltage With Clinical Characteristics and Recurrence of Arrhythmia in Patients Undergoing Ablation for Atrial Fibrillation

**Muhammad Haq** , Richard Amara, David Yoo, Aaron Kunamalla, Timm Dickfeld, Alejandro Jimenez Restrepo, Andrew Zohlman, Jeffrey Rottman, Stephen Shorofsky, Univ of Maryland Medical Ctr, Baltimore, MD; Vincent Y SEE, Univ of Maryland Sch of Med, Baltimore, MD

1:30 PM

Board # 2106

Clinical Significance of Improvement in Estimated Glomerular Filtration Rate After Atrial Fibrillation Ablation

**Sen Matsumoto** , Masashi Ishimi, Kenki Ashida, Masataka Sugahara, Kenji Kawai, Nobutaka Masunaga, Nagahiro Nishikawa, Yoshiyuki Kijima, Tohru Masuyama, JCHO Hoshigaoka Medical Ctr, Hirakata, Japan

1:30 PM

Board # 2107

Cryoballoon Pulmonary Vein Isolation is a Bailout for Hemodynamically Unstable Atrial Fibrillation in Patients With Severe Decompensated Heart Failure

**Yasuhiro Matsuda** , Masaharu Masuda, Mitsutoshi Asai, Osamu Iida, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takashi Kanda, Takuya Tsujimura, Shota Okuno, Hiroyuki Uematsu, Yuki Sato, Shodai Kawanami, Hiroki Sugae, Sho Nakao, Toshiaki Mano, Kansai Rosai Hosp, Amagasaki, Japan

1:30 PM

Board # 2108

Radiofrequency Delivery and Ablation Lesion Size Are Reduced by Ambient Circulation Surrounding an Ablation Catheter Tip

**Matthew M Zipse** , Ryan Borne, Lijun Zheng, Wendy S Tzou, William Sauer, Univ of Colorado, Aurora, CO; Duy Nguyen, Univ Colorado, Aurora, CO

# Abstract Poster Session

## AC.APS.12 - Prognosis and Therapies for Acute Coronary Syndromes II

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4060

Study on Adverse Clinical Events in Chronic Kidney Disease Patients With or Without Diabetes After Coronary Intervention: Japanese Multicenter Registry Data

**Suguru Nagamatsu** , Kenji Sakamoto, Noriaki Tabata, Kumamoto Univ, Kumamoto, Japan; Masanobu Ishii, Kumamoto Univ, Kumamoto, Japan, AL; Ryota Sato, Takayoshi Yamashita, Kota Motozato, Kenshi Yamanaga, Daisuke Sueta, Satoshi Araki, Yuichiro Arima, Kumamoto Univ, Kumamoto, Japan; Eiichiro Yamamoto, Kumamoto Univ Hosp, Kumamoto, Japan; Seiji Takashio, Koichiro Fujisue, Kumamoto Univ, Kumamoto, Japan; Kazuteru Fujimoto, Natl Hosp Organization Kumamoto Medical Ctr, Kumamoto, Japan; Hideki Shimomura, Fukuoka Tokushukai Medical Ctr, Kasuga, Japan; Ryusuke Tsunoda, Kumamoto Red Cross Hosp, kumamoto, Japan; Hideki Maruyama, Minamata City Hosp and Medical Ctr, Minamata, Japan; Natsuki Nakamura, Shinbeppu Hosp, Beppu, Japan; Sakaino Naritsugu, Amakusa Regional Medical Ctr, Amakusa, Japan; Shinichi Nakamura, Amakusa Medical Ctr, Hondo, Japan; Nobuyasu Yamamoto, Kumamoto Aging Res Inst, Kumamoto, Japan; Toshiyuki Matsumura, Kumamoto Rosai Hosp, Yatsushiro, Japan; Ichiro Kajiwara, Arao City Hosp, Arao, Japan; Shinji Tayama, Saiseikai Kumamoto Hosp, Kumamoto City, Japan; Tomohiro Sakamoto, Koichi Nakao, Saiseikai Kumamoto Hosp, Kumamoto, Japan; Shuichi Oshima, Kumamoto Central Hosp, Kumamoto City, Japan; Koichi Kaikita, Seiji Hokimoto, Kenichi Tsujita, Kumamoto Univ, Kumamoto, Japan

1:30 PM

Board # 4061

**Benefits and Risks of Ticagrelor or Prasugrel in Patients With Advanced Kidney Disease and** ST **-elevation Myocardial Infarctions: Real World Data From a German** STEMI- **Registry**

**Johannes Schmucker** , Harm Wienbergen, Andreas Fach, Rico Osteresch, Tina Retzlaff, Daniela Garstka, Stephan Michel, Tineke Wettwer, Rainer Hambrecht, Bremer Inst für Herz- und Kreislaufforschung am Klinikum Links der Weser, Bremen, Germany

1:30 PM

Board # 4062

Elevated Serum Phosphate Levels at Admission Are Associated With Worse Outcomes in Patients With Acute Myocardial Infarction

**Hiroaki Yokoyama** , Tomohide Endo, Fumie Nishizaki, Kenji Hanada, Takashi Yokota, Masahiro Yamada, Hirofumi Tomita, Hirosaki Univ Graduate Sch of Med, Hirosaki, Japan

1:30 PM

Board # 4063

Paroxysmal versus Non-Paroxysmal With Outcomes in Patients With Myocardial Infarction

**Poonam Bhyan** , Cape Fear Valley Medical Ctr, Fayettville, NC; Amandeep Goyal, Marietta Memorial Hosp, Marietta, OH; Sameer Arora, Univ of North Carolina, Chapel Hill, NC; Kishorbhai Gangani, Texas Health Arlington Memorial, Arlington, TX; Arman Qamar, Brigham and Women's Hosp, Boston, MA; John Paul Vavalle, Michael Yeung, Univ of North Carolina, Chapel Hill, NC

1:30 PM

Board # 4064

Use of Pulmonary Artery Catheters in Cardiac Intensive Care Units: Analysis From the Critical Care Cardiology Trials Network (CCCTN) Registry

**Bernard S Kadosh** , NYU Langone Health, New York, NY; Robert Roswell, Lenox Hill Hosp, Northwell Health, New York, NY; Anthony Delicce, Zucker Sch of Med at Hofstra/Northwell, Hempstead, NY; David Berg, Brigham and Women's Hosp, Boston, MA; Sean Van Diepen, Univ of Alberta, Edmonton, AB, Canada; Erin A Bohula, Brigham and Women's Hosp, Boston, MA; Jason N KATZ, Univ of North Carolina, Chapel Hill, NC; Jeong-Gun Park, David A Morrow, Brigham and Women's Hosp, Boston, MA; on behalf of the CCCTN Investigators

1:30 PM

Board # 4065

Impact of Dual Antiplatelet Therapy in Patients With Acute Coronary Syndromes and Reduced Left Ventricular Ejection Fraction

**Rocio Salsoso** , Paulo Genestreti, André Franci, Talia Dalcoquio, Carlos A Nakashima, Marco Scanavini, Aline G Ferrari, Insto do Coracao do Hosp das Clinicas da Faculdade de Medicina da Univ de Sao Paulo (InCor/HCFMUSP), Sao Paulo, Brazil; Remo H Furtado, Insto do Coracao do Hosp das Clinicas da Faculdade de Medicina da Univ de Sao Paulo (InCor/HCFMUSP), Sao Paulo, Brazil, Sao Paulo, Brazil; Felipe Gallego Lima, Roberto R Giraldez, Luciano Baracioli, Jose C Nicolau, Insto do Coracao do Hosp das Clinicas da Faculdade de Medicina da Univ de Sao Paulo (InCor/HCFMUSP), Sao Paulo, Brazil

1:30 PM

Board # 4066

Clinical Impact of the Prognostic Nutritional Index and Body Mass Index in Survival Patients With Acute Myocardial Infarction

Hyun Woong Park, **Hye Ree Kim** , Gyeongsang Natl Univ Hosp, Jinju, Korea, Republic of; Min Gyu Kang, GNUH, Jinju Gyeongsangnam-do, Korea, Republic of; Kyehwan Kim, Jin-Sin Koh, Gyeongsang Natl Univ Hosp, Jinju, Korea, Republic of; Jeong Rang Park, Samsung Medical Ctr, Seoul, Korea, Republic of; Seok-Jae Hwang, Seoul Natl, Seoul; Young-Hoon Jeong, Chamgwon Gyeongsang Natl Univ Hosp, Changwon, Korea, Republic of; Jong-Hwa Ahn, Gyeongsang Natl Univ Chan, Changwon; Jeong Yoon Jang, Asan Medical Ctr, Seoul, Korea, Republic of; Yongwhi Park, GNUH Changwon, Changwon; Jinyong Hwang, Gyeongsang Natl Univ Hosp, Jinju, Korea, Republic of

1:30 PM

Board # 4067

Comparative Prognosis Benefit of Angiotensin Converting Enzyme Inhibitor vs Angiotensin Receptor Blocker in Acute Coronary Syndrome in Patients With Preserved Left Ventricular Ejection Fraction

María Cespón Fernández, **Sergio Raposeiras Roubín** , Emad Abu-Assi, Isabel Muñoz Pousa, Rafael J. Cobas Paz, Berenice Caneiro Queija, Pablo Dominguez Erquicia, Luis Manuel Domínguez Rodríguez, Karim Jamhour Chelh, Luis Enrique Pérez Casares, Elena López Rodríguez, María Castiñeira Busto, Saleta Fernández Barbeira, Andres Iñiguez Romo, Hosp Univrio Álvaro Cunqueiro, Vigo, Spain

# Abstract Poster Session

## AC.APS.17 - Revascularization Strategies for Acute Myocardial Infarction

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4068

Time-to-controlled De-escalation Of Dual Antiplatelet Therapy Does Not Impact The Change Of Laboratory Level Of Platelet Inhibition In Primary Angioplasty

**Zuzana Jozefina Motovska** , Third Faculty of Med, Charles Univ and Univ Hosp Kralovske Vinohrady, Prague, Czech Republic; Robin Kralik, Martin Kamenik, Univ Hosp Kralovske Vinohrady, Prague, Czech Republic; Jiri Knot, UH Kralovske Vinohrady, Prague, Czech Republic; Michal Svoboda, Inst of Biostatistics and Analyses at the Faculty of Med Masaryk Univ, Brno, Czech Republic; Roman Miklik, Faculty of Med of Masaryk Univ and Univ Hosp Brno, Brno, Czech Republic; Petr Kala, Univ Hosp Brno, Brno, Czech Republic; Jiri Jarkovsky, Inst of Biostatistics and Analyses at the Faculty of Med Masaryk Univ, Brno, Czech Republic

1:30 PM

Board # 4069

Application and Clinical Benefit of Primary Percutaneous Coronary Intervention in Elderly Patients With Acute Myocardial Infarction - an Analysis From a Japanese Nationwide Database -

**Shiro Uemura** , Hiroshi Okamoto, Kawasaki Medical Sch, Kurashiki, Japan; Michikazu Nakai, Natl Cerebral Cardiovascular Ctr, Suita City, Japan; Kunihiro Nishimura, NCVC, Suita, Japan; Yoshihiro Miyamoto, Natl Cerebral and Cardiovascular, Suita, Japan; Masato Nakamura, Toho university, Ohashi medical Cen, Tokyo, Japan; Hiroyuki Tsutsui, Kyushu Univ, Fukuoka, Japan; Hisao Ogawa, Natl Cerebral Cardiovascular Ctr, Suita Osaka, Japan; Issei Komuro, Univ Tokyo, Tokyo, Japan; Yuji Ikari, Tokai Univ Sch of Med, Isehara, Kanagawa, Japan

1:30 PM

Board # 4070

Comparative Efficacy of Mechanical Interventions to Prevent Coronary No-Reflow: A Network Meta-Analysis

Julian Wendt, Felix Hofbauer, Matthias Stibleichinger, **Guenter Klappacher** , Medical Univ of Vienna, Vienna, Austria

1:30 PM

Board # 4071

Sonothrombolysis Improves Myocardial Dynamics and Microvascular Obstruction Preventing Left Ventricular Remodeling in Patients With ST Elevation Myocardial Infarction

Miguel O.D Aguiar, **Jeane Tsutsui** , Bruno G Tavares, Bernardo B. C. Lopes, Jose Nicolau, Hsu Po Chiang, Heart Inst (InCor), Univ of São Paulo, Medical Sch, Sao Paulo, Brazil; Thomas Porter, Univ Nebraska Medical Ctr, Omaha, NE; Bruno Carter C. Borges, Alexandre Soeiro, Múcio T. Oliveira Jr., Heart Inst (InCor), Univ of São Paulo, Medical Sch, Sao Paulo, Brazil; Carlos Rochitte, Heart Inst (InCor), Univ of São Paulo, Medical Sch, Sao Paulo, Brazil, Sao Paulo, Brazil; José A. F Ramires, Heart Inst (InCor), Univ of São Paulo, Medical Sch, Sao Paulo, Brazil; Roberto Kalil, Heart Inst (InCor), Univ of São Paulo, Medical Sch, Sao Paulo, Brazil, Sao Paulo, Brazil; Wilson Mathias, Heart Inst (InCor), Univ of São Paulo, Medical Sch, Sao Paulo, Brazil

1:30 PM

Board # 4072

Volume of Primary Angioplasty Procedures and Mortality in Relation to Low Population Density After Acute Myocardial Infarction

**Yasushi Matsuzawa** , Masaaki Konishi, Yusuke Saigusa, Masataka Taguri, Yokohama City Univ, Yokohama, Japan; Masaomi Gohbara, Yokohama City Univ Graduate Sch of Med, Yokohama, Japan; Toshiaki Ebina, Masami Kosuge, Yokohama City Univ, Yokohama, Japan; Kiyoshi Hibi, Yokohama, Yokohama, Japan; Kunihiro Nishimura, NCVC, Suita, Japan; Michikazu Nakai, Natl Cerebral and Cardiovascular Ctr, Suita City, Japan; Yoshihiro Miyamoto, Natl Cerebral and Cardiovascular, Suita, Japan; Satoshi Yasuda, Natl Cereb Cardiovascular Ctr, Osaka, Japan; Yoshihiko Saito, Nara Medical Univ, Nara, Japan; Naoki Nakayama, Ichiro Takeuchi, Kouichi Tamura, Kazuo Kimura, Yokohama City Univ, Yokohama, Japan

1:30 PM

Board # 4073

Efficacy And Safety Of Pharmacoinvasive Strategy Compared To Primary Percutaneous Coronary Intervention In The Management Of St-segment Elevation Myocardial Infarction: A Prospective Country-wide Registry

**Haitham Khraishah** , Beth Israel Deaconess Medical Ctr / Harvard Medical Sch, Boston, MA; Barrak Alahmad, T.H. Chan Sch of Public Health, Boston, MA; Abdulhamied Alfaddagh, The Johns Hopkins Hosp, Baltimore, MD; Mohammad Zubaid, Kuwait Univ, Safat

1:30 PM

Board # 4074

Coronary Artery Bypass Grafting Versus Percutaneous Coronary Intervention For Acute Myocardial Infarction With Cardiogenic Shock In The United States

**Nathaniel R Smilowitz** , New York Univ Medical Ctr, New York, NY; Carlos L Alviar, New York Univ, New York, NY; Stuart D Katz, New York Univ Sch Med, New York, NY; Judith S Hochman, NYU Sch of Med, New York, NY

1:30 PM

Board # 4075

Percutaneous Coronary Intervention to Unprotected Left Main Trunk Lesion in Patients With Acute Coronary Syndrome

**Hideki Wada** , Juntendo Univ Shizuoka Hospit, Izunokuni Shizuoka, Japan; Manabu Ogita, Juntendo Univ Shizuoka, Izunokuni, Japan; Satoru Suwa, Juntendo Univ Shizuoka Hosp, Izunokuni, Japan; Ryota Nishio, Kentaro Yasuda, Juntendo Univ Shizuoka Hospit, Izunokuni Shizuoka, Japan; Mitsuhiro Takeuchi, Juntendo Univ Shizuoka, Shizuoka, Japan; Shoichiro Yatsu, Juntendo Univ Shizuoka Hospit, Izunokuni Shizuoka, Japan; Katsumi Miyauchi, Hiroyuki Daida, Juntendo Univ, Tokyo, Japan

1:30 PM

Board # 4076

Lesion Location and Outcome in Patients With Multi-Vessel Disease and Acute Myocardial Infarction-Related Cardiogenic Shock, a Sub-Analysis of the Culprit-Shock Trial

Marie Hauguel-Moreau, Olivier Barthélémy, **Michel Zeitouni** , Paul Guedeney, Pitié-Salpêtrière Hosp, Paris, France; Stéphanie Rouanet, StatEthic, Paris, France; Georges Hage, Pitié-Salpêtrière Hosp, Paris, France; Pavel Overtchouk, CHU lille, lille, France; Benjamin Bertin, Pitié-Salpêtrière Hosp, Paris, France; Delphine Brugier, Action-Coeur, PARIS, France; Nicolas Vignolles, Pitié-Salpêtrière Hosp, Paris, France; Mathieu Kerneis, Heart Inst, Pitie Salpetriere Hosp, Paris 6 Univ, Paris, France; Johanne Silvain, Pitie-Salpetriere Hosp, PARIS, France; Jean-Philippe Collet, Pitié-Salpêtrière Hosp, Paris, France; Eric Vicaut, CHU lariboisiere, Paris, France; Serdar Farhan, The Zena and M a Wiener Cardiovascular Inst, New York, NY; Uwe Zeymer, Klinikum Ludwigshafen, Ludwigshafen; Holger Thiele, Heart Ctr Leipzig, Leipzig, Germany; Gilles Montalescot, Hop Pitie Salpetriere, Paris, France

1:30 PM

Board # 4077

Cilostazol Based Triple versus Potent P2y12 Blockers Based Dual Antiplatelet Therapy in Patients With Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention

**Seung Woon Rha** , Woohyeun Kim, Byoung Geol Choi, Se Yeon Choi, Jinah Cha, Yoonjee Park, Dong Oh Kang, Won-Young Jang, Jah Yeon Choi, Jin Oh Na, Cheol Ung Choi, Chang Gyu Park, Hong-Seog Seo, Korea Univ Guro Hosp, Seoul, Korea, Republic of

# Abstract Poster Session

## QU.APS.08 - Risk Assessment and Clinical Prediction

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3170

Outcomes of Percutaneous Coronary Intervention for Unprotected Left Main Coronary Artery According to the Syntax I Score

**Arthur Shiyovich** , Rabin Medical Ctr, Petah Tikva, Israel; Leor Perl, Stanford Hosp and Clinics, Los Altos Hls, CA; Hana Vaknin-Assa, Gabi Greenberg, Abid Samara, Ran Kornowski, abid aasali, Rabin Medical Ctr, Petah Tikva, Israel

1:30 PM

Board # 3171

Association of Electronic Medical Record-Based Follow up Order With Thirty-Day Readmission Rates

**Kartik Telukuntla** , Cleveland Clinic Fndn, Cleveland, OH; Chetan Huded, Cleveland, OH; Tim Sobol, Cleveland, OH, Cleveland, OH; Kathleen A Kravitz, Benico Barzilai, Randall Carson Starling, Umesh Khot, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 3172

Non-Dietary Cardiovascular Health Metrics and Their Association With Patient-Reported Outcomes Among US Adults Without Cardiovascular Disease: The Medical Expenditure Panel Survey 2006 to 2015

**Victor Okunrintemi** , East Carolina Univ, Greenville, NC; Martin Tibuakuu, St. Luke's Hosp, Ballwin, MO; Nazir Savji, Johns Hopkins Medical Insts, baltimore, MD; Salim S Virani, Michael E Debakey VA-Baylor, Bellaire, TX; Neil J Stone, Feinberg Sch of Med, Chicago, IL; Ron Blankstein, Brigham and Womens Hosp, Boston, MA; Roger S Blumenthal, Johns Hopkins Hosp, Baltimore, MD; Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD

1:30 PM

Board # 3173

Lack Oral Anticoagulation Explains Differences in Stroke Risk by Urban versus Non-Urban Residence in Medicare Beneficiaries

**Jingchuan Guo** , Meiqi He, Jared W Magnani, Walid F Gellad, Inmaculada Hernandez, Univ of Pittsburgh, Pittsburgh, PA

1:30 PM

Board # 3174

Percutaneous Coronary Intervention and Inpatient Mortality in Spontaneous Coronary Artery Dissection: A Propensity Score Analysis

**Pedro Covas** , The George Washington Univ, Washington, DC; Talal Alzahrani, George Washington Univ, Arlington, VA; Raza Yunus, Christian Nagy, Joseph Krepp, The George Washington Univ, Washington, DC

1:30 PM

Board # 3175

Association Between Timing of Recurrence and Risk of 1-Year Mortality After Hospital Discharge From Acute Myocardial Infarction

**Jiali Song** , Fuwai Hosp, Beijing, China; Javier Valero-Elizondo, Yale Univ/Yale-New Haven Hosp, New Haven, CT; Shuang Hu, Xi Li, Jing Li, Fuwai Hosp, Beijing, China; Yun Wang, Harvard T.H. Chan Sch of Public Health, Boston, MA; Harlan M Krumholz, Yale Univ/Yale-New Haven Hosp, New Haven, CT; Xin Zheng, Fuwai Hosp, Beijing, China

1:30 PM

Board # 3176

Clinical Trial Design for Management of Heart Failure Using a Nested Veteran Cohort to Determine Cardiovascular Mortality Linked to Prior Combat Exposure

**Thomas R. Roesel** , Cervoe.org, Bozman, MD; John F. Schmedtje, Virginia Circulation Res Ctr, Roanoke, VA

1:30 PM

Board # 3177

Clinical Outcomes and Predictors of Mortality in Out-of-Hospital Cardiac Arrest Patients Without ST Elevation: A Systematic Review and Meta-Analysis

**Beni R Verma** , Vikram Sharma, Shashank Shekhar, Cleveland Clinic, Cleveland, OH; Manpreet Kaur, Cleveland Clinic Fndn, Cleveland, OH; Samir R Kapadia, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 3178

Prevalence and Predictors of Early Discontinuation From Antihypertensive Treatment Among New York City Medicaid Beneficiaries: the Case for Early Adherence Intervention and First-line Treatment With ACEi/ARBs

**Adam B Schweber** , Siqin Ye, Columbia Univ, New York, NY; Gabriel S. Tajeu, Temple Univ, Philadelphia, PA; Ian M Kronish, Columbia Univ, New York, NY

1:30 PM

Board # 3179

Impact Of Prognostic Nutritional Index On Patients With Acute Myocardial Infarction

**Takuya Ando** , Kazuhiko Nakazato, Takatoyo Kiko, Takeshi Shimizu, Akiomi Yoshihisa, Takayoshi Yamaki, Hiroyuki Kunii, Takafumi Ishida, Yasuchika Takeishi, Fukushima Medical Univ, Fukushima, Japan

1:30 PM

Poster Professor

Emily C Obrien, Durham, NC

# Abstract Poster Session

## AC.APS.15 - Risk Following ACS: Danger Lurks Everywhere!

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4099

Age Stratified Analysis in Acute Myocardial Infarction Cardiogenic Shock. Insights From the National Cardiogenic Shock Initiative

**Alejandro Lemor** , Mir Babar Basir, Henry Ford Hosp, Detroit, MI; Navin K Kapur, Tufts Medical Ctr, Hanover, MA; Kirit Patel, Murad A Salam, St Joseph Mercy Oakland, Detroit, MI; Theodore L Schreiber, Amir Kaki, Ascension St John Hosp, Detroit, MI; Ivan D Hanson, William Beaumont Hosp, Troy, MI; Steve Almany, Steven Timmis, Beaumont Hosp, Detroit, MI; Simon R Dixon, William Beaumont Hosp, Royal Oak, MI; Brian C Kolski, UCSD, San Diego, CA; Josh Todd, Fort Sanders Regional Medical Ctr, ., CA; Shaun Senter, Washington Regional Medical Ctr, ., WA; Steven Marso, Heart and Vascular Institue, Kansas City, MO; David Lasorda, Cardiology Associates, Pittsburgh, PA; Charles Wilkins, San Juan Regional Heart Ctr, Farmington, NM; Thomas LaLonde, Antonious Attallah, Ascension St John Hosp, ., MI; Timothy Larkin, Edward and Elmhurst Hosp, ., IL; Allison Dupont, Jeffrey Marshall, Northeast Georgia Medical Ctr, ., GA; Nainesh Patel, Tjuan Overly, LA; Michael Green, Northwest Medical Ctr, ., AZ; Behnam Tehrani, INOVA Heart and Vascular Inst, Falls Church, VA; Alexander George Truesdell, Rahul Sharma, Virginia Heart, McLean, VA; Yasir Akhtar, ., ., TN; Thomas McRae III, Tristar Centennial Medical Ctr, ., TN; Brian P O'Neill, Temple Univ; John Finley IV, Temple Univ, Manassas, VA; Ayaz M Rahman, Cardiology Assoc East Tennessee, Atlanta, TN; Malcolm Foster, Turkey Creek Medical Ctr, Knoxville, TN; Raza Askari, ., Memphis, TN; Andrew Michael Goldsweig, Univ of Nebraska Med Ctr, Omaha, NE; Scott Martin, Aditya Bharadwaj, Stamford Hosp, ., CT; Matheen Khuddus, North Florida Regional Medical Ctr, Florida, FL; Christopher Caputo, Denes Korpas, North Florida Regional Medical Ctr, ., FL; Ian M Cawich, Nimrod Blank, Univ of Arkansas, Little Rock, AR; M Chadi M Alraies, Akshay Khandelwal, Wayne State Univ - DMC, Detroit, MI; Khaldoon Alaswad, Tyrell Johnson, Michael Hacala, William O'Neill, Henry Ford Hosp, Detroit, MI; National Cardiogenic Shock Initiative Investigators

1:30 PM

Board # 4100

Higher Post Discharge Bleeding Risk Observed Among East Asian Women After Percutaneous Coronary Intervention: A Gender Difference Analysis

**Masaki Kodaira** , Japan Red Cross Ashikaga Hosp, Ashikaga, Japan; Mitsuaki Sawano, Keio Univ, Tokyo, Japan; Toshiki Kuno, Mount Sinai Beth Israel, New York, NY; Yohei Numasawa, Japan Red Cross Ashikaga Hosp, Ashikaga, Japan; Ikuko Ueda, Keio Univ Sch of Med, Tokyo, Japan; Keiichi Fukuda, Shun Kohsaka, Keio Univ, Tokyo, Japan

1:30 PM

Board # 4101

One-Year Outcome Following Acute Phase Switching Among P2y12 Inhibitors; Results From the Real-World Database of Japan Ami Registry (JAMIR)

**Satoshi Honda** , Misa Takegami, Natl Cerebral and Cardiovascular Ctr, Osaka, Japan; Nishihira Kensaku, Miyazaki Medical Association Hosp, Miyazaki, Japan; Sunao Kojima, Kawasaki Medical Sch, Okayama, Japan; Yasuhide Asaumi, Natonal Cerebral and Cardiovascular Ctr, Suita, Japan; Makoto Suzuki, Sakakibara Heart Inst, Tokyo, Japan; Masami Kosuge, Yokohama City Univ Medical Ctr, Yokohama, Japan; Jun Takahashi, Yasuhiko Sakata, Tohoku Univ, Sendai, Japan; Morimasa Takayama, Tetsuya Sumiyoshi, Sakakibara Heart Inst, Tokyo, Japan; Hisao Ogawa, Natl Cerebal Cardiovascular Ctr, Suita Osaka, Japan; Kazuo Kimura, Natl Cerebral and Cardiovascular Ctr, Yokohama, Japan; Satoshi Yasuda, Natl Cereb Cardiovascular Ctr, Osaka, Japan

1:30 PM

Board # 4102

Incidence and Prognostic Impact of Sepsis in Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock. Results of the CULPRIT-SHOCK Study and Registry

**Uwe Zeymer** , Klinikum Ludwigshafen, Ludwigshafen, Germany; Steffen Desch, Univ of Leipzig Heart Ctr, Leipzig; Suzanne de Waha, Heart Ctr Leipzig, Leipzig; Gilles Montalescot, Hop Pitie Salpetriere, Paris, France; Ralf Zahn, Herzzentrum Ludwigshafen, Gruenstadt, Germany; Holger Thiele, Univ Leipzig - Heart Ctr, Leipzig

1:30 PM

Board # 4103

Rehospitalization and Recurrence Are Associated With Psychological Distress in Spontaneous Coronary Artery Dissection: An International Multi-Center Collaborative Study

David Adlam, Univ of Leicester, Leicester; Azza M Ahmed, Mayo Clinic, Rochester, MN; Abtehale Al-Hussaini, Imperial Coll London, London, United Kingdom; Sara Bouajila, Stanford Cardiovascular Inst, Stanford, CA; Eric Chow, Quantitative Sciences Unit, Stanfor, Palo Alto, CA; **Katharine Sears Edwards** , Stanford Univ, Stanford, CA; Sharonne N Hayes, Mayo Clinic, Rochester, MN; M. Ihsan Kaadan, Brandeis Univ, Waltham, MA; Rajani Kaimal, Stanford Univ, Stanford, CA; Esther Sh Kim, Vanderbilt Univ, Nashville, TN; Kevin S Masters, Univ of Colorado Denver, Denver, CO; Nalin Natarajan, Univ of Leicester NHS Trust, Manchester; Vedant Satish Pargaonkar, Stanford Sch of Med, Stanford, CA; Nilesh J Samani, Glenfield Hosp, Leicester, United Kingdom; Jonathan A Shaffer, Univ of Colorado Denver, Denver, CO; Jennifer A Sumner, Columbia Univ Medical Ctr, New York, NY; Jennifer A Tremmel, Stanford Univ Medical Ctr, Stanford, CA; Marysia Tweet, Coll Med Mayo Clinic Rochester, Rochester, MN; Tina Pittman Wagers, Univ of Colorado Boulder, Boulder, CO; Alice Wood, Univ of Leicester, Leicester; Malissa J Wood, Harvard Univ, Boston, MA

1:30 PM

Board # 4104

Can Syntax Scores Predict Major Cardiac Events in People Living With Human Immunodeficiency Virus Presenting With Acute Coronary Syndrome?

Raphael Robert, Dijon Univ Hosp, Dijon, France; Yves Cottin, Hop Francois Mitterrand, Dijon, France; Valerie Potard, Murielle Mary-Krause, INSERM, Sorbonne Univ, Inst Pierre Louis d'Épidémiologie et de Santé Publique (IPLESP), Paris, France; Sylvie Lang, AP HP - Saint Antoine Hosp, Paris CEDEX 12, France; Emmanuel Teiger, Henri Mondor Univ Hosp, Creteil, France; Nadjib Hammoudi, Pitié Salpêtrière Univ Hosp, Paris, France; Marion Chauvet-Droit, Saint Antoine Univ Hosp, Paris, France; Stephane Ederhy, Hop Saint Antoine, Paris, France; Laurie Dufour-Soulat, Saint Antoine Univ Hosp, Paris, France; Yann Ancedy, Saroumadi Adavane-Scheuble, Pascal Nhan, Saint Antoine Univ Hosp, Paris CEDEX 12, France; Philippe Gabriel Steg, Hop Bichat, Paris Cedex 18, France; Christian J Funck-Brentano, Hop Pitie-Salpêtriere, Paris, France; Pierre Marie Girard, Saint Antoine Univ Hosp, Paris, France; Dominique Costagliola, INSERM, Sorbonne Univ, Inst Pierre Louis d'Épidémiologie et de Santé Publique (IPLESP), Paris, France; Ariel A Cohen, Saint Antoine Hosp APHP, Paris, France; **Franck Boccara** , Saint Antoine Univ Hosp, Paris, France

1:30 PM

Board # 4105

Development and Validation of a Long-Term Bleeding Prediction Score in Patients Undergoing Percutaneous Coronary Intervention and Subsequent Dual Antiplatelet Agent Using Real-World Data

**Jin-Ho Choi** , Jung Min Choi, Seung Hwa Lee, Yu Jeung Jang, Samsung Medical Ctr, Seoul, Korea, Republic of; Joo Myung Lee, Seoul Natl Univ Hosp, Seoul, Korea, Republic of; Taek Kyu Park, Samsung Medical Ctr, Seoul, Korea, Republic of; Jeong Hoon Yang, Samsung Medical Ctr, Mayo Clinic, Seoul, Korea, Republic of; Young Bin Song, Samsung Medical Ctr, Seoul, Korea, Republic of; Joo-Yong Hahn, Samsung Medical Ctr, Sungkyunkwan Univ Sch of Med, Seoul, Korea, Republic of; Seung-Hyuk Choi, Samsung Medical Ctr, Seoul, Korea, Republic of; Hyeon-Cheol Gwon, Samsung Medical Ctr, Sungkyunkwan Univ Sch of Med, Seoul, Korea, Republic of; Sang Hoon Lee, Samsung Medical Ctr, Seoul, Korea, Republic of

1:30 PM

Board # 4106

Venoarterial Extracorporeal Membrane Oxygenation in Acute Coronary Syndrome Due to Left Main Trunk

**Haruko Shiota** , Eisuke Kagawa, Masaya Kato, Noboru Oda, Eiji Kunita, Michiaki Nagai, Hiroshima City Asa Hosp, Hiroshima, Japan; Keigo Dote, Hiroshima, Hiroshima, Japan

1:30 PM

Board # 4107

Delineating The Prognostic Value of Post PCI FFR in Acute Coronary Syndrome Patients

**Shiv Kumar Agarwal** , Univ of Arkansas for Medical Sciences, Little Rock, AR; Srikanth Vallurupalli, Aisha Siraj, UAMS, Little Rock, AR; Rahil Rafeedheen, Univ of Arkansas for Medical Sciences, Little Rock, AR; Mohammed Eid Madmani, Univ of Arkansas, Little Rock, AR; Rimsha Hasan, UAMS, Little Rock, AR; Mohamed Ayan, Univ of Arkansas for Medical Sciences, Little Rock, AR; Negar Salehi, Univ of Arkansa for Medical Sciences, Little ROck, AR; Srikanth Kasula, Malek Al-Hawwas, UAMS, Little Rock, AR; Abdul Hakeem, Rutgers Robert Wood Johnson Univ Hosp, New Brunswick, NJ; Barry F Uretsky, Univ of Arkansa for Medical Sciences, Little ROck, AR

1:30 PM

Board # 4108

Application of the Global Registry of Acute Coronary Events (GRACE) and Thrombolysis in Myocardial Infarction (TIMI) Risk Scores in Type 2 Myocardial Infarction

**Sean Murphy** , Cian McCarthy, Joshua Cohen, Saad Rehman, Maeve Jones O Connor, David Olshan, Massachusetts General Hosp, Boston, MA; Avinainder Singh, Yale-New Haven Hosp, New Haven, CT; Muthiah Vaduganathan, Brigham and Women's Hosp, Boston, MA; Jinghan Cui, James L Januzzi, Jason Wasfy, Massachusetts General Hosp, Boston, MA

# Abstract Poster Session

## EP.APS.31 - Screening, Costs and Healthcare Utilization

#### Zone 3, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 3081

Healthcare Resource Utilization and Costs Among Nonvalvular Atrial Fibrillation Patients Initiating Rivaroxaban or Warfarin in Skilled Nursing Facilities: A Retrospective Cohort Study

V Simon Mittal, LTC Professionals, Maplewood, MN; Bingcao Wu, Ji Song, **Dejan Milentijevic** , Veronica Ashton, Janssen Scientific Affairs, LLC, Titusville, NJ; Dheeraj Mahajan, Univ of Illinois at Chicago and Advocate Illinois Masonic Medical Ctr, Melrose Park, IL

1:30 PM

Board # 3082

Machine Learning Predicts Cardiovascular Risk and Cost Burden After Acute Coronary Syndromes

**Luiz Sergio F Carvalho** , Silvio Gioppato, State Univ of Campinas, Brasilia, Brazil; Marta D Fernandez, Clarity Healthcare Intelligence, Campinas, Brazil; Bernardo C Trindade, Cornell Univ, Ithaca, NY; Jose Carlos Quinaglia e Silva, Escola Superior de Ciências da Saúde, Brasilia, Brazil; Rebeca Gs Gouget, Brazilian Ministry of Economy, Brasilia, Brazil; Sandra Avila, Andrei Sposito, State Univ of Campinas, Campinas, Brazil

1:30 PM

Board # 3083

Patient Factors Associated With Delayed Diagnosis of Paroxysmal Supraventricular Tachycardia and the Resultant Impact on Healthcare Resource Utilization

**Naomi Sacks** , Madison Preib, Precision Xtract, Boston, MA; Katie Everson, Precision Health Economics, Austin, TX; Philip Cyr, Precision Xtract, Boston, MA; David Wood, Milestone Pharmaceuticals Inc, Saint-Laurent, QC, Canada; Sean Pokorney, Duke Univ, Raleigh, NC

1:30 PM

Board # 3084

A Remote Algorithmically-Driven Clinical Management Program Guiding Hypertension and Dyslipidemia Treatment is Cost-Effective

**Thomas Andrew Gaziano** , Brigham Womens Hosp, Boston, MA; Jorge Plutzky, Brigham and Women's Hosp, Boston, MA; Naomi Fisher, Brigham Womens Hosp, Boston, MA; Anton Dodek, AllWays Health Partners, Somerville, MA; Benjamin M Scirica, Calum A Macrae, Brigham and Women's Hosp, Boston, MA

1:30 PM

Board # 3085

Healthcare Resource Utilization Among Empagliflozin Initiators With and Without Cardiovascular Disease versus DPP4i in a Commercially-Insured Routine Care Population: An Analysis From the Empagliflozin Comparative Effectiveness and Safety (EMPRISE) Study

**Mehdi Najafzadeh** , Ajinkya Pawar, Sebastian Schneeweiss, Brigham and Women's Hosp, Boston, MA; Anouk Déruaz-Luyet, Global Epidemiology, Boehringer Ingelheim Intl GmbH, Ingelheim am Rhein, Germany; Kimberly Brodovicz, Boehringer Ingelheim, Ridgefield, CT; Anastasia Ustyugova, Boehringer Ingelheim Int GMBH, Ingelheim, Germany; Nileesa Gautam, Brigham and Women's Hosp, Boston, MA; Elisabetta Patorno, BWH Harvard Medical Sch, Boston, MA

1:30 PM

Board # 3086

Lipid Testing Trends in the US Before and After the Release of the 2013 ACC / AHA Cholesterol Guidelines

**Sara Levintow** , NoviSci, Durham, NC; Stephanie Reading, Amgen, Thousand Oaks, CA; Bradley Saul, Ying Yu, Diane Reams, Leah McGrath, NoviSci, Durham, NC; Kiran Philip, Paul Dluzniewski, Amgen, Thousand Oaks, CA; M. Alan Brookhart, NoviSci, Durham, NC

1:30 PM

Board # 3087

Major Depressive Disorder'S Cost to US Taxpayers: Increased Thirty-day Readmission and Total Hospital Cost Among Depressed Patients Admitted With Acute Myocardial Infarction

Kam Sing Ho, Mount Sinai St Luke's and West Hosp, New York, NY; Bharat Narasimhan, Mount Sinai St Luke's and West Hosp, New york, NY; **Lingling Wu** , Mount Sinai St Luke's and West, New York, NY; Shabnam Nasserifar, Jacqueline Sheehan, Eyal Herzog, Mount Sinai St Luke's and West Hosp, New York, NY

1:30 PM

Board # 3088

Association Between Hospital Debriefing Practices and Adherence to Resuscitation Process Measures for In-hospital Cardiac Arrest

**Ali O Malik** , Saint Lukes Mid America Heart Inst, Kansas City, MO; Brahmajee K Nallamothu, Brad Trumpower, Univ of Michigan, Ann Arbor, MI; Marci Kennedy, Khaja Chinnakondepalli, Saint Luke's Mid America Heart Inst, Kansas City, MO; Vittal Hejjaji, Saint Luke's Hosp Kansas City, Kansas City, MO; Firas Al Badarin, Saint Lukes Mid America Heart Ins, Kansas City, MO; Paul Chan, Saint Lukes Hosp / MAHI, Kansas City, MO

1:30 PM

Board # 3089

Primary Aldosteronism is Under-Diagnosed, Partially Due to Insufficient Screening

**Imran Ajmal** , Xiruo Ding, Jordana Cohen, Heather Wachtel, Debbie Cohen, Daniel S Herman, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 3090

LDL-C Values and Lipid Lowering Therapy Utilization Among Medicare Beneficiaries With a Recent Myocardial Infarction

**Nihar R. Desai** , Yale Sch of Med, New Haven, CT; Stefan DiMario, Belinda Schludi, Mohdhar Habib, Katie Mues, Amgen Inc., Thousand Oaks, CA; Kevin Dietz, Xian Shen, Avalere Health, Washington, DC

1:30 PM

Poster Professor

Rishi Wadhera, Boston, MA

# Abstract Poster Session

## CH.APS.20 - See the Heart: Optimizing Imaging of the Congenital Heart

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Poster Professor

Meryl S Cohen, Philadelphia, PA

1:30 PM

Board # 4163

Improving Cardiac MRI Ventricular Contouring In Tetralogy Of Fallot Using Machine Learning

Navina Mohan, UT Southwestern-Children's Dallas, Dallas, TX; Alborz Amir-Khalili, Circle Cardiovascular Imaging, Calgary, AB, Canada; Barbara E. U. Burkhardt, Univ Children's Hosp Zurich, Zurich, Switzerland; Riad Abou Zahr, King Faisal Specialist Hosp and Res Ctr, Jeddah, Saudi Arabia; Cory Jensen, Circle Cardiovascular Imaging, Calgary, AB, Canada; Tarique Hussain, UT Southwestern-Children's Dallas, Dallas, TX; Gerald Greil, UT Southwestern Medical Ctr, Dallas, TX; Alireza Sojoudi, Circle Cardiovascular Imaging, Calgary, AB, Canada; **Animesh Tandon** , UT Southwestern-Children's Dallas, Dallas, TX

1:30 PM

Board # 4164

Multi-Vendor Three-dimensional Echocardiographic Evaluation of Normal Pediatric Left Ventricular Volumes and Function: A Multicenter Study

**Pei-Ni Jone** , Lisa Le, Childrens Hosp Colorado, Aurora, CO; Zhaoxing Pan, Univ of Colorado, Aurora, CO; Nee Khoo, Tim Colen, Stollery Children's Hosp, Edmonton, AB, Canada; Ben Goot, Children's Hosp of Wisconsin, Milwaukee, WI; Anitha Parthiban, Children's Mercy Hosp, Kansas City, MO; David M Harrild, Boston Childrens Hosp, Boston, MA; Alessandra M Ferraro, Gerald Ross Marx, Boston Children's Hosp, Boston, MA

1:30 PM

Board # 4165

Left Atrial Strain is Impaired in Children With Hypertrophic Cardiomyopathy: A Pilot Study

**Jolie Britt** , Joseph Spinner, John Colquitt, Asela Nieuwsma, Ricardo H Pignatelli, Robert Loar, Baylor Coll of Med/Texas Children's Hosp, Houston, TX

1:30 PM

Board # 4166

Cardiovascular Magnetic Resonance Derived Single Ventricle Global Function Index is Associated With Fontan Failure and Exercise Capacity in Patients Late After the Fontan Operation

**Tarek Alsaied** , Paul J Critser, Cincinnati Children's Hosp, Cincinnati, OH; Nina Azcue, Andrew J Powell, Rahul Rathod, Boston Children's Hosp, Boston, MA

1:30 PM

Board # 4167

Cardiac CT vs Invasive Coronary Angiography in Pediatric Post-Cardiac Transplantation Associated Coronary Allograft Vasculopathy

**Vasu Gooty** , Jeanne Dillenbeck, Nathanya Hernandez, Richard Kirk, UT southwestern - Dallas Children's Medical Ctr, Dallas, TX; Ryan J Butts, Childrens Medical Ctr of Dallas, Dallas, TX; Tarique Hussain, UT Southwestern - Dallas Children's Medical Ctr, Dallas, TX

1:30 PM

Board # 4168

Texture Analysis of Cardiac Magnetic Resonance Native T1 Maps Characterizes the Proarrhythmic Substrate in Pediatric Myocarditis

**Ashish Doshi** , Johns Hopkins Univ, Baltimore, MD; Laura Olivieri, Children's Natl Medical Ctr, Washington, DC; Natalia Trayanova, Johns Hopkins Univ, Baltimore, MD

1:30 PM

Board # 4169

Are 3D Echocardiographic Ventricular Volumes Prior to Biventricular Repair Associated With Transplant-Free Survival in Unbalanced Atrioventricular Canal Defect?

**Claire Cigarroa** , Melinda Shea, Kimberlee Gauvreau, Boston Children's Hosp, Boston, MA; David M Harrild, Boston Childrens Hosp, Boston, MA; Sitaram Emani, Gerald Ross Marx, Boston Children's Hosp, Boston, MA

1:30 PM

Board # 4170

Normal Fetal Ventricular Strain by 2-Dimensional Speckle Tracking Echocardiography With Novel Imaging Modality With Higher Frame Rate and Spatial Resolution

**Kohta Takei** , Satoshi Yasukochi, Kiyohiro Takigiku, Noboru Tanaka, Kosuke Yonehara, Haruka Obinata, Ryusuke Numata, Satoshi Koyama, Masato Masamoto, Yuriko Yamada, Nagano Children's Hosp, Azumino, Nagano, Japan

1:30 PM

Board # 4171

Cardiac Magnetic Resonance Aids in Detection of Cardiac Allograft Vasculopathy in Pediatric Heart Transplant Patients

Nazia Husain, Kae Watanabe, Haben Berhane, Lurie Children's Hosp, Chicago, IL; Arif Jivan, Northwestern Memorial Hosp, Chicago, IL; Daniel C Lee, Northwestern Univ, Chicago, IL; **Joshua D Robinson** , Lurie Children's Hosp, Chicago, IL; Michael Markl, Northwestern Univ, Chicago, IL; Cynthia K Rigsby, Ann & Robert H Lurie Children's Hosp of Chicago, Chicago, IL

1:30 PM

Board # 4172

Role of Cardiac MRI and Computational Modeling in Assessment of Coronary Blood Flow Patterns in Children With Intramural Anomalous Aortic Origin of Coronary Arteries Post Unroofing Surgery

**Shagun Sachdeva** , Baylor Coll of Med, Houston, TX; Atefeh Razavi, John LaDisa, Marquette Univ, Milwaukee, WI; Peter C Frommelt, Medical Coll of Wisconsin, Milwaukee, WI

1:30 PM

Board # 4173

Changes In Fetal/Embryonic Heart Function Components In The Late First/Early Second Trimester Of Human Pregnancy

**Angela McBrien** , Dora Gyenes, Univ of Alberta, Edmonton, AB, Canada; C Monique Bohun, Univ of New Mexico, Albuquerque, NM; Jesus Serrano-Lomelin, Univ of Alberta, Edmonton, AB, Canada; Silvia GV Alvarez, McMaster Univ, Hamilton, ON, Canada; Lisa W Howley, Children's Heart Clinic, Aurora, CO; Venu Jain, Tarek Motan, Lisa K Hornberger, Univ of Alberta, Edmonton, AB, Canada

1:30 PM

Board # 4174

3d Advanced Imaging Overlay With Rapid Registration in Congenital Heart Disease to Reduce Radiation and Assist Cardiac Catheterization Interventions

**Yousef Arar** , Surendranath R. Veeram Reddy, Heidi Kim, Thomas M Zellers, V. Vivian Dimas, Riad Abou Zahr, Animesh A Tandon, Alan W Nugent, Tarique Hussain, Univ of Texas Southwestern, Dallas, TX

1:30 PM

Board # 4175

Variation in Utilization of Transthoracic Echocardiography in Initial Outpatient Pediatric Cardiac Encounters

**Kenan WD Stern** , Mount Sinai Children's Heart Ctr, New York, NY; Courtney E McCracken, Scott E Gillespie, Emory Univ, Atlanta, GA; Christopher J Statile, Cincinnati Childrens Hosp, Cincinnati, OH; Leo Lopez, Lucile Packard Children's Hosp, Palo Alto, CA; George R Verghese, Lurie Children's Hosp, Chicago, IL; Nadine Choueiter, Children's Hosp at Montefiore, Bronx, NY; Ritu Sachdeva, Emory Univ Sch of Med, Atlanta, GA

1:30 PM

Board # 4176

Trends in Diagnosis of Asymptomatic Anomalous Aortic Origin of Coronary Artery Over the Last Two Decades by Transthoracic Echocardiography in Age Less Than 30 Years

**Neha Ahluwalia** , Kenan Stern, Ira Parness, Irene Lytrivi, Shubhika Srivastava, Mount Sinai Medical Ctr, New York, NY

# Abstract Poster Session

## SA.APS.14 - Team Science: Findings from Peri-Operative Care in Patients Undergoing CV Surgery

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4281

Dexmedetomidine Reduces Circulating Microparticles-induced Chemotaxis of Neutrophils Through Foxo3a Pathway

**Jingsong Ou** , Cai -Yun Chen, Hao-Xiang Yuan, Yu-Quan Li, Yan Li, Zhijun Ou, Kang-Qing Xu, The First Affiliated Hosp, Sun Yet-Sen Univ, Guangzhou, China

1:30 PM

Board # 4282

Functional Status After Prolonged Intensive Care Unit Stays in Postoperative Cardiac Surgery Patients

**Bipin Sunkara** , Thomas Curran, Allie Thompson, Univ of Michigan, Ann Arbor, MI; Adrian Lim, Promedica Toledo Hosp, Toledo, OH; Jonathan Haft, Univ Michigan, Ann Arbor, MI; Milo Engoren, Univ of Michigan, Ann Arbor, MI

1:30 PM

Board # 4283

Postoperative Acute Kidney Injury is Common and Associated With Increased Mortality in Patients Undergoing Cardiac Surgery: Insights From the LEVO-CTS Trial

**Oliver K Jawitz** , Amanda S Stebbins, Vignesh Raman, John H Alexander, Rajendra Mehta, Mark Stafford-Smith, Renato D Lopes, Duke Univ Medical Ctr, Durham, NC

1:30 PM

Board # 4284

Impact of Post-discharge Angiotensin-converting Enzyme Inhibitors/Angiotensin Receptor Blockers on Mortality in Patients With Asymptomatic Troponin Elevation in the Perioperative Period

**Parag Anilkumar Chevli** , Wake Forest Sch of Med, Winston Salem, NC; Hanumantha R Jogu, Wake Forest Sch of Med, WINSTON SALEM, NC; Tareq Islam, Wake Forest Sch of Med, Winston Salem, NC; Abhishek Dutta, Wake Forest Baptist hospital, winston salem, NC; Padageshwar Sunkara, Romesa B Ameen, Chi-Cheng Huang, Wake Forest Sch of Med, Winston Salem, NC

1:30 PM

Board # 4285

Postoperative Thrombocytopenia - A Predictive Surrogate For Poor Survival Following Acute Type A Aortic Dissection Repair

Harleen K Sandhu, **Akiko Tanaka** , Eric W Linville, Nicholas Zhou, Kenton L Rommens, Charles C Miller III, Hazim J Safi, Anthony L Estrera, McGovern Medical Sch at the Univ of Texas Health Science Ctr at Houston (UTHealth) and Heart and Vascular Inst at Memorial Hermann Hosp, Houston, TX

1:30 PM

Board # 4286

Effects of Bisoprolol Transdermal Patch for Perioperative Myocardial Injury in Patients Undergoing Non-cardiac Surgery : Multi-center Randomized Controlled Trial

**Takayuki Iwano** , Kazufumi Nakamura, Hironobu Toda, Kentaro Ejiri, Koji Nakagawa, Masashi Yoshida, Atsuyuki Watanabe, Toru Miyoshi, Nobuhiro Nishii, Kazuyoshi Shimizu, Masao Hayashi, Hiroshi Morita, Hiroshi Morimatsu, Hiroshi Ito, Okayama Univ, Okayama, Japan

1:30 PM

Board # 4287

Intrathoracic Right Subclavian Cannulation in Aortic Arch Surgery

Elizabeth Norton, Creighton Univ, Omaha, NE; Xiaoting Wu, Alexander Makkinejad, Linda Farhat, **Bo Yang** , Univ of Michigan, Ann Arbor, MI

1:30 PM

Board # 4288

A Predictive Score Combining C-Reactive Protein and Albumin Predicts 30-day Mortality After Cardiac Surgery

**Kuo Lin Colin Huang** , Univ of Melbourne, Parkville VIC, Australia; Rohan Navani, Univ of Melbourne, Parkville, Australia; Arul Baradi, David Jin, St Vincent's Hosp, Melbourne, Fitzroy, Australia; Jacqueline Nguyen, Zachary Ellis, Univ of Melbourne, Parkville, Australia; Andrew Newcomb, Andrew Wilson, St Vincent's Hosp, Melbourne, Fitzroy, Australia

# Abstract Poster Session

## IN.APS.15 - Therapeutic Considerations during PCI

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4249

Virtual Fractional Flow Reserve Computed Through Design of Experiments Has Significant Correlation With Pressure Wire Fractional Flow Reserve

**Javad Hashemi** , Narayana Sarma Singam, Travis R Huffman, Robert E Berson, Shahab Ghafghazi, Univ of Louisville, Louisville, KY

1:30 PM

Board # 4250

Feasibility of Coronary Angiogram-based Computational Modelling of Fractional Flow Reserve in Everyday Practice

**Hazel Arfah Preston** , Samuel Stroud, Sheffield Teaching Hosp, Sheffield, United Kingdom; Katherine Lal, Univ of Sheffield, Sheffield, United Kingdom; Rebecca Gosling, Paul Morris, Sheffield Teaching Hosp, Sheffield, United Kingdom; Pat Lawford, David R Hose, Julian Gunn, Univ of Sheffield, Sheffield, United Kingdom

1:30 PM

Board # 4251

Strategic Considerations in the Utilization of Physiologic Lesion Assessment in Multivessel Coronary Artery Disease

**Harsh Rawal** , Efehi Igbinomwanhia, Advocate Illinois Masonic Hosp, Chicago, IL; Christopher Kabir, Advocate Health Care, Chicago, IL; Lloyd Klein, Advocate Illinois Masonic Medical Ctr, Chicago, IL

1:30 PM

Board # 4252

Quantitative Assessment of Lipid Component by Nirs-ivus is Helpful for Differentiating Among Plaque Rupture, Erosion and Calcified Nodule in the Culprit Lesion of Acs

**Kosei Terada** , Wakayama Medical Univ, Wakayama, Japan; Takashi Kubo, Wakayama Medical Univ, Wakayama, Japan; Yoshiki Matsuo, Yasushi Ino, Kunihiro Shimamura, Yasutsugu Shiono, Hiroki Emori, Yosuke Katayama, Atsushi Tanaka, Takeshi Hozumi, Takashi Akasaka, Wakayama Medical Univ, Wakayama, Japan

1:30 PM

Board # 4253

Personalized Antiplatelet Therapy Guided by a Novel Detection of Platelet Aggregation Function in Stable Coronary Artery Disease Patients Undergoing Pci: A Randomized Controlled Clinical Trial

**Ying-Ying Zheng** , Ting-Ting Wu, Yi Yang, Xian-Geng Hou, Ying Gao, You Chen, Yi-Ning Yang, Xiao-Mei Li, Xiang Ma, Yi-Tong Ma, First Affiliated Hosp of Xinjiang Medical Univ, Urumqi, China; Xiang Xie, First Affiliated Hosp of Xinjiang Medical Univ,, Urumqi, China

1:30 PM

Board # 4254

Prevalence and Prognostic Value of Elevated High-Sensitivity C-reactive Protein Differ Between Races/Ethnicities Undergoing Percutaneous Coronary Intervention

Moritz Blum, **Rishi Chandiramani** , Roxana Mehran, Davide Cao, Rachel Singleton, Ridhima Goel, Anastasios Roumeliotis, Icahn Sch of Med at Mount Sinai, New York, NY; Niklas Beyhoff, Charite Univsmedizin Berlin, Berlin, Germany; Vishal Kapur, Choudhury Hasan, Javed Suleman, Srinivas Kesanakurthy, George Dangas, Asaad Akbar Khan, Prakash Krishnan, Nitin Barman, Jason C Kovacic, Joseph Sweeny, Samin K. Sharma, Annapoorna Kini, Mount Sinai Hosp, New York, NY

1:30 PM

Board # 4255

Comparison of Three Years Outcomes After Different PCI Strategy for Bifurcation Lesion

**Jorge Palazuelos** , Damaris Carballeira, David Marti, Ricardo Concepcion, Edurne Lopez, Salvador Alvarez, Hosp Univrio Central de la Defensa Gomez Ulla, Madrid, Spain

1:30 PM

Board # 4256

Excimer Laser and Following Heparin Infusion Therapy is an Effective Therapy for Intraprocedual Stent Thrombosis

**Akihiro Tanaka** , Osaka Rosai Hosp, Sakai, Japan; Kyosuke Yanagawa, Osaka Rosai Hosp, Sakai-city, Japan; Hitoshi Nakamura, Yutaka Matsuhiro, Koji Yasumoto, Naotaka Okamoto, Yasuharu Matsunaga, Osaka Rosai Hosp, Sakai, Japan; Daisuke Nakamura, Osaka rosai hospital, Sakai, Japan; Masamichi Yano, 3-1179, Sakai, Japan; Masaki Yamato, Yasuyuki Egami, Ryu Shutta, Masami Nishino, Osaka Rosai Hosp, Sakai, Japan

1:30 PM

Board # 4257

AZD3366-an Optimized Recombinant Human Apyrase Combining Anti Platelet, Anti Inflammatory and Tissue Protective Actions With Low Bleeding Risk for Potential Mitigation of Thromboembolic Complications

Susanne Pehrsson, Bengt Kull, Daniel Hovdal, Marie Elebring, Carl Whatling, Ola Fjellstrom, **Leif Carlsson** , AstraZeneca, Gothenburg, Sweden

1:30 PM

Board # 4258

Clinical Effects of Shorter Dual Antiplatelet Therapy Duration After Drug-Eluting Stents: A Network Bayesan Meta-Analysis of Randomized Clinical Trials

**Giuseppe Ferrante** , Fausto Roccasalva, Francesco Cannata, Pier P Pasquale Leone, Paolo Pagnotta, Giulio Stefanini, Reimers Bernhard, Humanitas Res Hosp, Rozzano Milan, Italy

1:30 PM

Poster Professor

Roxana Mehran, New York, NY

1:30 PM

Board # 4260

Stent Thrombosis With and Without Aspirin After Pci in Patients With Atrial Fibrillation

**Nick D. Fagel** , Jean-Paul R. Herrman, Freek Verheugt, OLVG, Amsterdam, Netherlands

1:30 PM

Board # 4261

Abbreviation of Eptifibatide Therapy Improves Safety in STEMI Patients Undergoing Primary Percutaneous Coronary Intervention

**Florian Fischer** , Triemli Hosp, Zurich, Switzerland; Samriddhi Buxy, Ulrike Held, Univ of Zurich, Zurich, Switzerland; David J. Kurz, Triemli Hosp, Zurich, Switzerland; Oliver Senn, Univ of Zurich, Zurich, Switzerland; Franz R Eberli, Rainer Zbinden, Matthias R Meyer, Triemli Hosp, Zurich, Switzerland

# Abstract Poster Session

## GE.APS.05 - Unbiased Omics

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1150

Global Metabolomic Profiling Reveals Lower Lysophospholipids Levels in Multiple Myeloma Patients With Carfilzomib-Related Cardiotoxicity

**Yimei Huang** , Timothy J Garrett, Lihui Yuan, Univ of Florida, Gainesville, FL; Michael G Fradley, H. Lee Moffitt Cancer Ctr & Res Inst, Tampa, FL; Robert F Cornell, Vanderbilt Univ Medical Ctr, Nashville, TN; Rachid C Baz, H. Lee Moffitt Cancer Ctr & Res Inst, Tampa, FL; Chintan P Shah, Taimour Langaee, Nida Waheed, Carl J Pepine, Univ of Florida, Gainesville, FL; Moreb S Jan, Novant Health Forsyth Medical Ctr, Winston Salem, NC; Yan Gong, Univ of Florida, Gainesville, FL

1:30 PM

Board # 1151

Analysis of the Serum Metabolic Profile of Patients With Advanced Coronary Heart Disease And Patients With Severe Aortic Stenosis Without Coronary Heart Disease. The Pilot Study

**Anna Slowikowska** , Medical Univ of Warsaw, Warsaw, Poland; Beata Toczylowska, IBBE, Warsaw, Poland; Romuald Cichon, Medinet Heart Ctr, Wroclaw, Poland; Piotr Hendzel, Medical Univ of Warsaw, Warsaw, Poland

1:30 PM

Board # 1152

Metabolomics Characterization of Human Calcific Aortic Valve Stenosis

**Arun Surendran** , St. Boniface Hosp Res, Winnipeg, MB, Canada; Mahesh Chandran V. R, Aneesh Kumar. A, Rajiv Gandhi Ctr for Biotechnology, Thiruvananthapuram, India; Andrea L Edel, Davinder S Jassal, St. Boniface Hosp Res, Winnipeg, MB, Canada; Abdul Jaleel K.A, Rajiv Gandhi Ctr for Biotechnology, Thiruvananthapuram, India; Amir Ravandi, St. Boniface Hosp Res, Winnipeg, MB, Canada

1:30 PM

Board # 1153

Blood RNA Biomarkers of Coronary Artery Disease: RNA Sequencing Reveals a Signature of Regulatory T Cell Imbalance

Ian V Toma, George Washington Univ, Washington, DC; Richard J Katz, George Washington Univ Med Ctr, Washington, DC; Jonathon Reiner, The George Washington Univ Medical Ctr, Washington, DC; Ramesh Mazhari, George Washington Univ, Washington, DC; Palak Shah, Inova Heart And Vascular Inst, Falls Church, VA; Michael Tackett, Daniel Jones, SeqLL, Inc, Woburn, MA; Georges St. Laurent III, The St. Laurent Inst, Woburn, MA; Dmitry Shtokalo, Denis Antonets, A.P. Ershov Inst of Informatics Systems, Novosibirsk, Russian Federation; Justin Ertle, The George Washington Univ, Washington, DC; Tisha Jepson, True Bearing Diagnostics, Inc, Washington, DC; **Timothy A McCaffrey** , The George Washington Univ, Washington, DC

1:30 PM

Board # 1155

Systems Genetics Identified Wide Spectrum Genetic Variants and Common Genetic Regulators in Left Ventricular Noncompaction Cardiomyopathy Patients

Fuiy Xu, Univ of Tennessee Health Science, Memphis, TN; John Warren Collyer, UTHSC Coll of Med, Memphis, TN; Undral Munkhsaikhan, UTHSC, Memphis, TN; Wenying Zhang, Cincinnati Children's Hosp Medi, Cincinnati, OH; Lu Lu, Univ of Tennessee, Memphis, Memphis, TN; **Enkhsaikhan Purevjav** , Univ of Tennessee Health Science, Memphis, TN; Jeffrey A Towbin, Le Bonheur Children's Hosp, Memphis, TN

1:30 PM

Board # 1156

Associations Between Apolipoprotein A-I Proteoforms and Markers of Cardiometabolic Health

**John T Wilkins** , Northwestern Univ, Chicago, IL; Henrique Seckler, Northwestern Univ, Evanston, IL; Jonathan S. Rink, Northwestern Univ, Chicago, IL; Colby Thaxton, Northwestern Univ Feinberg Sch of Med, Chiacog, IL; Philip Compton, Northwestern Univ, Evanston, IL; Allan D. Sniderman, Royal Victoria Hosp, Montreal, QC, Canada; Luca Fornelli, The Univ of Oklahoma, Norman, OK; Richard LeDuc, Northwestern Univ, Evanston, IL; David R. Jacobs Jr., Univ of Minnesota, Minneapolis, MN; Donald M Lloyd-jones, Northwestern Univ, Chicago, IL; Neil Kelleher, Northwestern Univ, Evanston, IL

1:30 PM

Board # 1157

Metabolites Associated With Per- and Polyfluoroalkyl Substance (PFAS) Levels in an Ethnically Diverse Underserved At-Risk Rural Population

**Jawan W Abdulrahim** , Heather M Stapleton, Maggie Nguyen, Lydia C Kwee, Olga Ilkayeva, Duke Univ, Durham, NC; Cherry M Beasley, Univ of North Carolina at Pembroke, Pembroke, NC; John W Stanifer, Munson Medical Ctr, Traverse City, MI; Svati H Shah, Duke Univ Medical Ctr, Hillsborough, NC

1:30 PM

Board # 1159

1 **Hnmr Spectroscopy Reveals Only Subtle Differences Between Serum Metabolome of Metabolically Healthy Obese Subjects and Subjects With Metabolic Syndrome**

Kamila Osadnik, Tadeusz Osadnik, Medical Univ of Silesia, Katowice, Poland; Tadeusz Bieg, Silesian Univ of Technology, Gliwice, Poland; Mateusz Lejawa, Martyna Fronczek, Mariusz Gąsior, Natalia Pawlas, Medical Univ of Silesia, Katowice, Poland; **Maciej Banach** , Medical Univ of Lodz, Lodz, Poland

1:30 PM

Poster Professor

Jane F Ferguson, Nashville, TN

1:30 PM

Board # 1160

East Asians Mitochondrial Aldehyde Dehydrogenase 2 Genotypes Exacerbate the Nitrate Tolerance and Endothelial Dysfunction

Yuji Mizuno, **Eisaku Harada** , Fumihito Kugimiya, Kumamoto Aging Res Inst, Kumamoto, Japan; Michihiro Yoshimura, The Jikei Univ Sch of Med, Tokyo, Japan; Hirofumi Yasue, Kumamoto Aging Res Inst, Kumamoto, Japan

# Abstract Poster Session

## CH.APS.21 - Understanding Pediatric Heart Disease

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4184

Whole Genome Sequencing Provides Insight Into the Genetic Composition Underlying CHD Severity

**Gillian M Blue** , The Children's Hosp at Westmead, Sydney, Australia; Eddie Ip, Victor Chang Cardiac Res Insti, Darlinghurst, Australia; Gary F Sholler, The Children's Hosp at Westmead, Sydney, Australia; Richard P Harvey, Victor Chang Cardiac Res Inst, Darlinghurst, Australia; Eleni Giannoulatou, Victor Chang Cardiac Res Insti, Darlinghurst, Australia; Sally L Dunwoodie, Victor Chang Cardiac Res Insti, Sydney, Australia; David S Winlaw, The Children's Hosp at Westmead, Sydney, Australia

1:30 PM

Board # 4177

Children and Adolescents With Marfan Syndrome: 10,000 Healthy Steps and Beyond

**Elif Seda Selamet Tierney** , Angela Chen, Stanford Univ, Palo Alto, CA; Katie Jo Stauffer, Lucile Packard Children's Hosp, Palo Alto, CA; Jerrid Brabender, Stanford Childrens, San Mateo, CA; Ronnie T Collins, Stanford Univ, Palo Alto, CA; Daniel J Murphy, Stanford Univ Med Ctr, Palo Alto, CA; George Sandor, Children's Heart Ctr, Vancouver, BC, Canada; Mitra Esfandiarei, Midwestern Univ, Glendale, AZ

1:30 PM

Board # 4185

Application of Population Specific Streptococcal Antibody Titers to Improve Specificity of Rheumatic Fever Diagnosis in Uganda

**Emmy Okello** , Ugadna Heart Inst, Kampala, Uganda; Emma Ndagire, Childrens Natl Health system, Washington, DC; Rachel Sarnacki, Children's Natl, Washington, DC; Meghna Murali, Children's Natl Medical Ctr, Washington, DC; Joselyn Rwebembera, The Uganda Heart Inst, Kampala, Uganda; Tom Parks, London Sch of Hygiene and Tropic, London; Nicholas de Klerk, Telethon Kids Inst, Nedlands, Australia; Chris Longenecker, Case Western Reserve Univ, Cleveland, OH; Jonathan Carapetis, Telethon Inst for Child Health Res, Perth, Australia; Craig A Sable, Childrens Natl Medical Ctr, Potomac, MD; Andrea Z Beaton, Cincinnati Childrens Hosp Medic, Washington, DC

1:30 PM

Board # 4183

Occult Diastolic Dysfunction is Associated With Adverse Clinical Outcomes in Adolescents and Young Adults With Fontan Circulation

**Daniel Peck** , Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; Konstantin Averin, Stollery Childrens Hosp, Edmonton, AB, Canada; Philip Khoury, Grant Veldhuis, Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; Russel Hirsch, Cincinnati Children's Hosp, Cincinnati, OH; Wendy Whiteside, Michigan Med Congenital Heart, Ann Arbor, MI; Gruschen Veldtman, Cincinnati Children's Hosp Medical Ctr, Cincinnati, OH; Bryan H Goldstein, Cincinnati Children's Hosp, Cincinnati, OH

1:30 PM

Board # 4178

Resource Use and Outcomes of Children With Congenital Heart Disease Admitted to the Hospital From 2003 to 2016

**Jonathan B Edelson** , Children's Hosp of Philadelphia, Philadelphia, PA; Joseph William Rossano, Children's Hosp of Philadelphia, Haverford, PA; Heather Griffis, Children's Hosp of Phialdelphia, Philadelphia, PA; William Quarshie, CHOP, Philadelphia, PA; Chitra Ravishankar, Childrens Hosp of Philadelphia, Philadelphia, PA; Matthew J O'Connor, Univ of Pennsylvania Perelman Sch of Med, Philadelphia, PA; Christopher Mascio, Laura A Mercer-Rosa, Andrew C Glatz, Kimberly Y Lin, Children's Hosp of Philadelphia, Philadelphia, PA

1:30 PM

Board # 4181

Quality of Life is Associated With Age and Executive Function in Children With Congenital Heart Disease

**Nicole M. Hemphill** , Christine Voss, Mimi T. Y. Kuan, Jimmy Lopez, Ashutosh Sharma, Penny L. Sneddon, Univ of British Columbia, Vancouver, BC, Canada; Kevin C. Harris, BC Children s Hosp, Vancouver, BC, Canada

1:30 PM

Board # 4182

Higher Number of Transition Visits Are Associated With Decreased Gaps in Care for Youth With Congenital Heart Disease

**Keila N Lopez** , Baylor Coll of Med, Houston, TX; Donna K Lovick, Nicole S Broussard, Baylor Coll of Med/Texas Children's Hosp, Houston, TX; Yunfei Wang, Jason L Salemi, Baylor Coll of Med, Houston, TX

1:30 PM

Board # 4179

Feasibility of Wave Intensity Analysis as a Tool for Measuring Abnormal Systolic Function in Young Fontan Patients

**John Valdovinos** , California State Univ Northridge, Northridge, CA; Matthew Russell, Daniel S Levi, UCLA Mattel Children's Hosp, Los Angeles, CA

# Abstract Poster Session

## HF.APS.41 - VAD and Transplant: New Insights

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2262

Autoregulation of Pulsatile Bioprosthetic Artificial Heart Allow Conservation of Endothelial Homeostasis

**David M Smadja** , Richard Chocron, Bastien Poitier, Paris Descartes Univ, Paris, France; Yury Pya, Mahabbat Bekbossynova, Natl Res Cardiac Surgery Ctr, Astana, Kazakhstan; Christophe Peronino, Paris Descartes Univ, Paris, France; Jean Christian Roussel, Inst du Thorax - CTCV, Nantes Cedex 1, France; Michel Kindo, Univ Hosp of Strasbourg, Strasbourg, France; Antoine Capel, Carmat SA, Velizy, France; Jean Christophe Perles, Carmat SAS, Vélizy Villacoublay, France; Piet Jansen, Carmat SAS, Paris, France; Peter Ivak, IKEM, Prague, Czech Republic; Christian Latremouille, Coralie Guerin, Paris Descartes Univ, Paris, France; Ivan Netuka, IKEM, Prague, Czech Republic

1:30 PM

Board # 2263

In-hospital Outcomes of Heart Transplant Patients and Ventricular Assist Device Patients With Cognitive Impairment

**Hilda Mariana Gonzalez Bonilla** , Olubode Olufajo, Howard Univ, Washington, DC; Ahmad Armoghan Yousuf Awan, Urooj Fatima, Howard Univ Hosp, Washington, DC; Mohammad Sadegh Asadi, Isaac Opoku Asare, Howard Univ, Washington, DC

1:30 PM

Board # 2264

Cross Comparison of Continuous Flow Total Artificial Heart: Adult, Pediatric and Infant Device Assessment in Virtual Model

**Jamshid H Karimov** , Cleveland Clinic, Cleveland, OH; David J Horvath, R1 Engineering, Euclid, OH; Anthony R Polakowski, Dennis W Horvath, Takuma Miyamoto, Yuichiro Kado, Barry D Kuban, Hani Najm, Elizabeth V Saarel, Kiyotaka Fukamachi, Cleveland Clinic, Cleveland, OH

1:30 PM

Board # 2265

The Use of Angiotensin II Antagonism in Patients With Left Ventricular Assist Device is Associated With Reduced Risk of Gastrointestinal Hemorrhage: A Systematic Review and Meta-Analysis

**Wasawat Vutthikraivit** , Texas Tech Health Sciences Ctr, Lubbock, TX; Veraprapas Kittipibul, Jackson Memorial Hosp Internal Med Residency Program, Miami, FL; Jakrin Kewcharoen, Univ of Hawaii, Honolulu, HI; Saif El Nawaa, Texas Tech Univ HSC, Lubbock, TX; Barbara Mantilla, TBD, Lubbock, TX; M Rubayat Rahman, Texas Tech Univ, Lubbock, TX; Mohamed Elmassry, Texas Tech Univ Health S C, Lubbock, TX; Pablo Paz, Texas Tech Univ Health Sciences Ctr, Lubbock, TX; Pattara Rattanawong, Univ of Hawaii, Honolulu, HI; Prapaipan Putthapiban, Einstein Medical Ctr, Philadelphia, PA

1:30 PM

Board # 2267

A Population‐Level Analysis to Compare Trends, Co-morbidities, Complications and Predictors of In-hospital Mortality in Patients With Left Ventricular Assist Device From 2010 to 2014

**Karthik Gonuguntla** , Shivaraj P Patil, Univ of Connecticut, Hartford, CT; Richard G Cowden, Univ of the Free State, Bloemfontein, South Africa; Harshith Thyagaturu, Bassett Medical Ctr, Cooperstown, New York, NY; Peter Robinson, Univ of Connecticut, Hartford, CT

1:30 PM

Board # 2268

Impella 5.0 as a Bridge to Clinical Decision Making

**Daniel W Nelson** , Sakthi Kumar Sundararajan, Medical Coll of Wisconsin, Wauwatosa, WI; Asim Mohammed, Froedtert and the Medical Coll of Wisconsin, Brookfield, WI

1:30 PM

Board # 2269

Predictors of Post-Transplant Improvement in Functional Capacity in Patients Debilitated Prior to Transplant Using United Network From Organ Sharing (UNOS) Database

**Vivek Modi** , Mount Sinai St. Luke's and Roosevelt Medical Ctr, New York, NY; Dhrubajyoti Bandyopadhyay, Mount Sinai St. Luke's and Roosevelt Medical Ctr, New York, NY, NY; Rishi Shrivastav, Mount Sinai St. Luke's and Roosevelt Medical Ctr, New York, NY; Supriya Shore, Univ of Michigan, Ann Arbor, MI; Monique Tanna, Univ of Michigan, Ann Arbor, MI, Philadelphia, PA; Jeremy A Mazurek, Edo Birati, Univ of Pennsylvania, Philadelphia, PA; Arieh Fox

1:30 PM

Board # 2270

Discordance Between Immunofluorescence and Immunohistochemistry C4d Staining is a Risk Factor for Adverse Outcomes Post Heart Transplantation

**Takeo Fujino** , Yuto Kumai, Benjamin Yang, Sara Kalantari, Jayant Raikhelkar, Kammi Henriksen, Anthony Chang, Aliya N Husain, Gene Kim, Gabriel Sayer, Nir Uriel, Univ of Chicago, Chicago, IL

1:30 PM

Board # 2271

Atrial Fibrillation is Associated With Recurrent Ventricular Arrhythmias After Lvad Implant: Incidence and Impact in a Consecutive Series

**Isaac Goldenthal** , Columbia Univ Irving Medical Ctr, New York, NY; Kathleen T Hickey, Columbia Univ, Trumbull, CT; Paolo C Colombo, Columbia Univ Irving Medical Ctr, New York, NY; Yoshifumi Naka, Columbia/Presbyterian, New York, NY; Arthur R Garan, Columbia Univ, Brooklyn, NY; Melana Yuzefpolskaya, Columbia Univ Medical Ctr, New York, NY; Hasan Garan, New York Presbyterian Medical Ctr, New York, NY; Elaine Y Wan, Columbia Univ Medical Ctr, New York, NY; Robert Sciacca, Columbia Univ Sch of Nursing, New York, NY; Angelo B Biviano, Columbia Univ Medical Ctr, New York, NY

# Abstract Poster Session

## AT.APS.22 - Vascular Differentiation and Regeneration II

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 1073

Combined Mechanotransduction and Pharmacological Conditioning for Improved Therapeutic Angiogenesis of Mesenchymal Stem Cells

**Andrew Sligar** , The Univesity of Texas at Austin, Austin, TX; Jason Lee, Univ of Texas at Austin, Austin, TX; Kayla Henderson, Pablo Maceda, Miguel Armenta Ochoa, Eun Yoon, Lara Samarneh, Austin Veith, Mitchell Wong, Andrew Dunn, The Univesity of Texas at Austin, Austin, TX; Aaron Baker, Univ of Texas at Austin, Austin, TX

1:30 PM

Board # 1074

Shear Stress Meditated Enhancement Of Vascular Phenotypes In Human Mesenchymal Stem Cells

**Andrew Sligar** , The Univ of Texas at Austin, Austin, TX; Jason Lee, Univ of Texas at Austin, Austin, TX; Varsha Karanam, Chaarushena Deb, The Univ of Texas at Austin, Austin, TX; Victoria Le, Aaron Baker, Univ of Texas at Austin, Austin, TX

1:30 PM

Board # 1075

Transmembrane Stem Cell Factor Nanodiscs Enhance Revascularization in Ischemia and Have Less Mast Cell Activation

**Eri Takematsu** , Jeff Auster, Aditya Singh, Po-Chih Chen, Sophia Canga, Sanjana Srinath, Andre Degroot, Univ of Texas at Austin, Austin, TX; Michael Sherman, Univ of Texas Medical Branch, Galveston, TX; Jeanne Stachowiak, Andrew K Dunn, Univ of Texas at Austin, Austin, TX; Aaron Baker, Univ of Texas at Austin, Austin, TX

1:30 PM

Board # 1076

The Treatment Strategies to Zero Out the Complications of Coronary Artery Aneurysm Considering in Four-Step Risk Classification in the Acute Phase of Kawasaki Disease

**Yukako Yoshikane** , Fukuoka Univ Chikushi Hosp, Fukuoka, Japan; Tatsuki Miyamoto, Shinichi Hirose, Fukuoka Univ, Fukuoka, Japan; Atsushi Ogawa, Atsushi Ogawa, Fukuoka Univ Chikushi Hosp, Fukuoka, Japan

1:30 PM

Board # 1077

Etv2-RhoJ **and Hippo Signaling Cascade Regulates Endothelial Progenitors During Embryonic Development**

**Bhairab N. Singh** , Wuming Gong, Satyabrata Das, Univ of Minnesota, Minneapolis, MN; Joshua Theisen, Javier Sierra-Pagan, UMN, Minneapolis, MN; Pruthvi Shah, Erik Skie, Mary G Garry, Univ of Minnesota, Minneapolis, MN; Daniel J Garry, Lillehei Heart Inst - U of MN, Minneapolis, MN

1:30 PM

Board # 1078

Cross-talk Between Endothelial Cells and Pericyte-like Smooth Muscle Cells is Mediated by Complementary Paracrine and Wnt/Planar Cell Polarity (PcP) Signalling

**Mirabelle Sh Ho** , Ketul R Chaudhary, Duncan J Stewart, Ottawa Hosp Res Inst, Ottawa, ON, Canada

1:30 PM

Board # 1079

Vesselin, a Novel Regulator for Vascular Morphogenesis, Regulates Neovascularization After Ischemia

**Yanqing A Gong** , Maohuan Lin 19104, Yanling Wang 19104, Zhengqiang He 19104, Hao Duan 19104, Menggui Huang 19104, Yi Fan 19104, Univ of Pennsylvania, Philadelphia, PA

1:30 PM

Board # 1080

Klf4 Dependent Plasticity of Perivascular Cells is Detrimental for Diet Induced Obesity Associated Adipose Tissue Inflammation and Fibrosis

**Gamze B Bulut** , Gabriel Alencar, Vlad Serbulea, Univ of Virginia, Charlottesville, VA; Gary K Owens, Univ Virginia, Charlottesville, VA

1:30 PM

Poster Professor

Tohru Fukai, Augusta, GA

1:30 PM

Board # 1081

Decreased Inspired Oxygen Stimulates New Collateral Formation in the Heart

**Amir Aghajanian** , UNC Chapel Hill, Chapel Hill, NC; Hua Zhang, Univ of North Carolina, Chapel Hill, NC; Brian Buckley, UNC Chapel Hill, Chapel Hill, NC; Erika S Wittchen, Univ of North Carolina-CH, Chapel Hill, NC; Mark D Levin, NIH, NHLBI, Bethesda, MD; James Faber, UNC Chapel Hill, Chapel Hill, NC

1:30 PM

Board # 1082

Extracellular Vesicle Mediated Therapeutic Angiogenesis in Peripheral Arterial Disease

**Ao Shi** , Timothy E Peterson, D Kent K Arrell, Raman Deep Singh, Tyra A Witt, Mary Nagel, Fabrice Lucien, Andre Terzic, Atta Behfar, Mayo Clinic, Rochester, MN

# Abstract Poster Session

## EA.APS.37 - Ventricular Tachycardia Ablation

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 2153

Cardiac MRI Structural and Functional Predictors of LVEF Recovery Following PVC Catheter Ablation

**Jessica Mao** , The Johns Hopkins Hosp, Baltimore, MD; Eric Xie, Johns Hopkins Sch of Med, Baltimore, MD; Elzbieta Chamera, The Johns Hopkins Hosp, Baltimore, MD; Joao A Lima, Johns Hopkins Univ, Baltimore, MD; Jonathan Chrispin, Johns Hopkins Hosp, Baltimore, MD

1:30 PM

Board # 2154

Intracardiac Echocardiography Use During Catheter Ablation for Ventricular Tachycardia: Is There a Difference in Outcome?

**Michael Field** , Medical Univ of South Carolina, Charleston, SC; Laura Goldstein, Johnson & Johnson Medical Devices, Irvine, CA; Stephanie Lee, Johnson & Johnson Medical Devices, Singapore, Singapore; Iftekhar Kalsekar, Charlene Wong, Rahul Khanna, Johnson & Johnson, New Brunswick, NJ; Matthew R Reynolds, Lahey Hosp and Medical Ctr, Burlington, MA; Jeffrey Winterfield, Medical Univ of South Carolina, Charleston, SC

1:30 PM

Board # 2155

Clinical Outcomes of Remote Magnetic Navigation Ablation of Papillary Muscle Versus Right Ventricular Outflow Tract Premature Ventricular Contractions

**Neil Beri** , Xin Zhang, Pankaj Malhotra, Dali Fan, Nayereh Pezeshkian, Uma Srivatsa, Univ of California Davis, Medical Ctr, Sacramento, CA

1:30 PM

Board # 2156

Conventional vs Fluoroless Catheter Ablation in Ventricular Tachycardia: A Single Center Experience

Araba Bruce-Mensah, **Brittney Heard** , Pamela Mason, Rohit Malhotra, Kenneth Bilchick, UVA Medical Ctr, Charlottesville, VA; John Ferguson, SCL Health Heart & Vascular Inst, Denver, CO; J Michael Mangrum, Univ of Virginia, Charlottesville, VA; Andrew Darby, Nishaki Mehta, UVA Medical Ctr, Charlottesville, VA

1:30 PM

Board # 2157

Severity of Coronary Atherosclerosis Does Not Predict Hemodynamic Intolerance of Ventricular Tachycardia During Catheter Ablation

**Giovanni E Davogustto** , Andrew Cluckey, Vanderbilt Univ, Nashville, TN; Arvindh Kanagasundram, Vanderbilt, Brentwood, TN; Jay Alan Montgomery, Vanderbilt Univ Hosp, Nashville, TN; Sharon Shen, Vanderbilt Univ Medical Ctr, Nashville, TN; Roy M John, Vanderbilt Univ, Nashville, TN; Gregory F Michaud, William G Stevenson, Vanderbilt Univ Medical Ctr, Nashville, TN

1:30 PM

Board # 2158

Long Term Outcome of Endocardial Only Ablation of Ventricular Tachycardia in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

**Cory M Tschabrunn** , Univ of Pennsylvania, Philadelphia, PA; Erica S Zado, Hosp of the Univ of PA, Philadelphia, PA; Pasquale Santangeli, Matthew Hyman, Univ of Pennsylvania, Philadelphia, PA; Fermin Carlos Garcia, Hosp of the Univ of PA, Philadelphia, PA; Gregory Supple, Univ of Pennsylvania, Philadelphia, PA; David S Frankel, Univ of Pennsylvania Health System, Philadelphia, PA; David J Callans, Hosp Univ Pennsylvania, Washington Crossing, PA; Francis E Marchlinski, Univ of Pennsylvania, Bala Cynwyd, PA

1:30 PM

Board # 2159

Compared to Medications, Ablation is Safe and More Effective in Controlling Ventricular Tachycardia in Left Ventricular Assist Device Patients

**Ryan Cotter** , Natalie Beck, Megan Kunkel, Alexis Z Tumolo, Amneet Sandhu, Nicholas Mantini, Blake Fleeman, Brian Miller, Ryan Borne, Duy Nguyen, Christine Tompkins, Joseph Schuller, Ryan G Aleong, William Sauer, Matthew Zipse, Wendy S Tzou, Univ of Colorado, Aurora, CO

1:30 PM

Board # 2160

Substrate Mapping and Catheter Ablation of Recurrent Ventricular Tachycardia in a Patient With Ischemic Cardiomyopathy Following Stereotactic Radioablation

**Pierre C Qian** , Brigham and Women's Hosp, Boston, MA; Usha Tedrow, Brigham Womens Hosp, Boston, MA; Martin Aguilar, Brigham and Women's Hosp, Boston, MA; Kenneth Quadros, Brigham and Womne's Hosp, Boston, MA; Scott Friesen, Fred Hacker, Raymond Mak, Paul Zei, Brigham and Women's Hosp, Boston, MA

1:30 PM

Board # 2161

Early Catheter Ablation of Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy With Recurrent Shocks From Implantable Cardioverter Defibrillator - A Multicenter Study

Adnan Yousaf, Metrohealth Medical Ctr, Cleveland, OH; **Muhammad U Ali** , Hywel Dda Health Board, Llanelli, United Kingdom; Mohammad Aldweik, Cardiff and Vale Univ Health Board, Cardiff, United Kingdom; Ahmed M Hailan, Abertawe Bro Morgannwg Univ Health Board, Swansea, United Kingdom

# Abstract Poster Session

## CH.APS.18 - Well Being in CHD

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 1:30 PM - 2:00 PM

1:30 PM

Board # 4139

Rapid Advancement in Enteral Nutrition Does Not Affect Systemic Inflammation and Insulin Homeostasis Following Pediatric Cardiopulmonary Bypass Surgery

**Alejandro A Floh** , Joann Herridge, Chun-po Steve fan, Cedric Manlhiot, The Hosp for Sick Children, Toronto, ON, Canada; Brian W McCrindle, Hosp for Sick Children, Toronto, ON, Canada; Glen S Van Arsdell, David Geffen Sch of Med at UCLA, Los Angeles, CA; Diana Balmer-Minnes, The Hosp for Sick Children, Toronto, ON, Canada; Steven M Schwartz, Hosp for Sick Children, Toronto, ON, Canada

1:30 PM

Board # 4140

Quality of Life and Disability Status Among Young Adults With Congenital Heart Defects, Congenital Heart Survey to Recognize Outcomes, Needs, and Wellbeing, 2016-2019

**Karrie F Downing** , Ctrs for Disease Control and Prevention, Atlanta, GA; Matthew Oster, Emory Univ Sch of Med, Atlanta, GA; Jennifer Andrews, Scott E Klewer, Univ of Arizona, Tucson, AZ; Wendy N Nembhard, Univ of Arkansas for Medical Sciences, Little Rock, AR; Sherry Farr, Ctrs for Disease Control and Prevention, Atlanta, GA

1:30 PM

Board # 4141

Trends in Palliative Care Use in Patients With Adult Congenital Heart Disease at the End-Of-Life

Vidang Nguyen, **Jill Steiner** , Eric Krieger, Univ of Washington, Seattle, WA; Yonatan Buber, Univ of Washington Medical Ct, Seattle, WA; Karen Stout, UW Med, Seattle, WA

1:30 PM

Board # 4142

Lifelong Impact and Risk-Factors for Community Acquired Pneumonia in Congenital Heart Disease

**Patrick D Evers** , Cincinnati Children's Hosp, Cincinnati, OH; Dora Farkas, Univ of Aarhus, Aarhus, Denmark; Morten Olsen, Aarhus Univ Hosp, Aarhus, Denmark; Nicolas L Madsen, Cincinnati Children's Hosp, Cincinnati, OH

1:30 PM

Board # 4143

Prognostic Awareness of Parents snd Physicians in Hospitalized Children With Advanced Heart Disease

**Emily Morell** , Children's Hosp Los Angeles, Los Angeles, CA; Mary Katherine Miller, Chase Samsel, Kevin G Friedman, Roger E Breitbart, Lynn A Sleeper, Jeffrey R Reichman, Elizabeth D Blume, Boston Children's Hosp, Boston, MA

1:30 PM

Board # 4144

Executive Function Outcomes in Children and Adolescents With Repaired D-TGA, TOF and Fontan Palliation

**Amara Majeed** , David Wypij, Valerie Rofeberg, Boston Children's Hosp, Boston, MA; David Bellinger, Jane Newburger, Boston Children's Hosp, Boston, MA

1:30 PM

Board # 4145

Assessment of Energy and Protein Intakes in Relation to Clinical Outcomes in Infants Following Cardiopulmonary Bypass

**Li Jia** , Guangzhou Women and Children's Medical Ctr, Guangzhou, China; Jian Zhang, Capital Inst of Pediatrics, Graduate Sch of Peking Union Medical Coll, Beijing, China; Yan-Qin Cui, Xin-Xin Chen, Guangzhou Women and Children's Medical Ctr, Guangzhou, China

1:30 PM

Board # 4146

Brain Injury and Outcomes in Patients With Heterogenous Neonatal Congenital Heart Diseases

**Rachel Vassar** , Shabnam Peyvandi, Univ of California, San Francisco, San Francisco, CA; Steven Miller, Hosp for Sick Children, Toronto, ON, Canada; Patrick McQuillen, Univ of California, San Francisco, San Francisco, CA

1:30 PM

Board # 4147

The Impact of Poverty on Depression, Anxiety, and ADHD in Children With Congenital Heart Disease

**Vincent J Gonzalez** , Texas Children's Hosp/Baylor Coll of Med, Houston, TX; Rachel Kimbro, Katherine E Cutitta, Texas Children's Hosp, Houston, TX; Mohammad Bilal, Keila N Lopez, Baylor Coll of Med, Houston, TX

1:30 PM

Board # 4148

The Effect of Gestational Age and Size at Birth on Brain Injury and Developmental Outcomes in Congenital Heart Disease

**Shalin Parekh** , UCSF, San Francisco, CA; Martina Andrea Steurer, UCSF Dept of Pediatrics, San Francisco, CA; Vann Chau, Hosp for Sick Children, Toronto, ON, Canada; Whitnee Hogan, Duan Xu, UCSF, San Francisco, CA; Steven Miller, Hosp for Sick Children, Toronto, ON, Canada; Patrick S McQuillen, Univ California San Francisco, San Franciso, CA; Shabnam Peyvandi, Univ California San Fran, San Francisco, CA

1:30 PM

Board # 4149

Can a Clinical Modified Wang Respiratory Score Replace Nasal Nitric Oxide as Diagnostic for Ciliary Dysfunction in Congenital Heart Disease Patients?

Muhammad Junaid, Childrens Natl Medical System, Washington, DC; Phillip S Adams, Univ of Pittsburgh, Pittsburgh, PA; Murray Pollack, Childrens Natl Health Systems, Washington, DC; Omar Khalifa, Univ of Pittsburgh Sch of Med, Pittsburgh, PA; Robert McCarter, Childrens Natl Medical Ctr, Washington, DC; Iman Z Sami, Childrens Natl Medical System, Washington, DC; Richard A Jonas, Children's Natl Medical Ctr, Washington, DC; Mahesh Sharma, Univ of North Carolina Sch of Med, Chapel Hill, NC; Anastassios Koumbourlis, Childrens Natl Medical Ctr, Washington, DC; Joan Sanchez-de-Toledo, Daniel J Weiner, Univ of Pittsburgh Sch of Med, Pittsburgh, PA; **Cecilia W Lo** , Univ of Pittsburgh, Pittsburgh, PA; Linda Leatherbury, Childrens Natl Medical System, Washington, DC

1:30 PM

Board # 4150

Proposal of a New Quantitative Assessment Method for Pulmonary Vascular Volume Using Computed Tomography

**Masahito Yamashiro** , Jikei Univ Sch of Med, Tokyo, Japan; Toru Sakuma, Jikei Univ Sch of Med 3-25-8 Nishi-shimbashi,, Tokyo, Japan; Kiyozo Morita, Jikei.Univ Sch of Med, Tokyo, Japan; Kazuhiro Hashimoto, Jikei Univ Sch of Med, Tokyo, Japan

1:30 PM

Board # 4151

Coronary Artery Disesae in Hypoplastic Left Heart Syndrome Following Staged Palliation

**Sruti Rao** , Salima Bhimani, Cleveland Clinic Children's, Cleveland, OH; Lourdes R Prieto, Nicklaus Children's Hosp, Miami, FL; Rukmini R Komarlu, Cleveland Clinic Children's, Cleveland, OH

1:30 PM

Board # 4152

Dissociation Between Resting Echocardiographic Indices and Aerobic Capacity in Adults With Tetralogy of Fallot

**Alexander C Egbe** , Mayo Clinic, Rochester, MN

# Abstract Oral Session

## CA.AOS.548 - A Cornucopia of Approaches to Treat the Failing Heart: Without Tofurkey

#### 120A

### Monday, November 18, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Maria Irene Kontaridis, Utica, NY

2:00 PM

Moderator

Sarah M Schumacher, Cleveland, OH

2:00 PM

Non-coding RNA Regulation of Doxorubicin-induced Cardiac Cell Death and Dysfunction

John Henderson, **Mallikarjun Patil** , Hien T Luong, Divya Annamalai, Phuong Quach, Rajasekaran Namakkal-Soorappan, Prasanna Krishnamurthy, Univ of Alabama at Birmingham, Birmingham, AL

2:10 PM

Q & A

2:15 PM

Severe, but Not Mild Decreases in Nicotinamide Adenine Dinucleotide (NAD) Cause Heart Failure

**Timothy S Luongo** , Univ of Pennsylvania, Philadelphia, PA; Lin Wang, Princeton Univ, Princeton, NJ; Karthikeyani Chellappa, Univ of Pennsylvania, Philadelphia, PA; Melanie R McReynolds, Princeton Univ, Princeton, NJ; Daniel P Kelly, Univ of Pennsylvania, Philadelphia, PA; Joshua D Rabinowitz, Princeton Univ, Princeton, NJ; Joseph A Baur, Univ of Pennsylvania, Philadelphia, PA

2:25 PM

Q & A

2:30 PM

Remote Ischemic Preconditioning Attenuates Mortality, Left Ventricular Mass Decline, Cardiac Fibrosis and Apoptosis Following Doxorubicin Administration in Mice

Zachary Gertz, Virginia Commonwealth Univ, Richmond, VA; Chad Kenneth Cain, VCU Internal Med Cardiology, Richmond, VA; Donatas Kraskauskas, Teja Devarakonda, **Adolfo G Mauro** , Jeremy Thompson, Arun Samidurai, Qun Chen, Edward J Lesnefsky, Anindita Das, Fadi N Salloum, Virginia Commonwealth Univ, Richmond, VA

2:40 PM

Q & A

2:45 PM

A Single Cell Survey of Myocardium Identifies Cell Type-Specifc Molecular Changes in Heart Failure

**Man Rao** , Guangran Guo, Fuwai Hosp, Beijing, China; Xiliang Wang, Peking Univ, Beijing, China; Ulrich Hofmann, Univ Hosp Würzburg, Würzburg, Germany; Maarten Hulsmans, MGH - Harvard Medical Sch, Boston, MA; Xueda Hu, Peking Univ, Beijing, China; Jiangping Song, Shengshou Hu, Fuwai Hosp, Beijing, China

2:55 PM

Q & A

3:00 PM

LncExACT1 Inhibition Induces Physiological Cardiac Growth and Protects Against Heart Failure

**Haobo Li** , Xiaojun Liu, Chunyang Xiao, Guoping Li, Ashish Yeri, Massachusetts General Hosp, Boston, MA; Amrut V Ambardekar, Colorado Univ Denver, Aurora, CO; Peter M Buttrick, Univ of Colorado, Aurora, CO; Michael R Bristow, Univ Colorado-AMC, Aurora, CO; Anthony Rosenzweig, Massachusetts General Hosp, Boston, MA

3:10 PM

Q & A

# Abstract Oral Session

## GE.AOS.582 - Genomic and Epidemiology Mid-Career Research Award and Lecture

#### 121C

### Monday, November 18, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Thomas J Wang, Nashville, TN

2:00 PM

Moderator

Svati H Shah, Hillsborough, NC

2:00 PM

Genomic and Epidemiology Mid-Career Research Award and Lecture

Themistocles L Assimes, Palo Alto, CA

2:25 PM

Q & A

2:30 PM

Genome Wide Association Study of Heart Failure Identifies Seven Genetic Loci in the Million Veteran Program

**Jacob Joseph** , VA Boston& Brigham Womens Hosp, Boston, MA; Qin Hui, Emory Univ, Atlanta, GA; Serkalem Demissie, Brian Charest, Jp Casas, VA Boston, Boston, MA; John Michael Gaziano, tbd, Roxbury Xing, MA; Kelly Cho, Lauren Costa, VA Boston, Boston, MA; Katherine Kurgansky, Boston VA Healthcare System, Boston, MA; Peter Wf Wilson, Emory Clinical Cardiovascular Res Inst, Atlanta, GA; Lawrence Phillips, Emory Univ, Atlanta, GA; Christopher J O'Donnell, VABHS, Boston, MA; Yan Sun, Emory Univ, Atlanta, GA

2:40 PM

Q&A

2:45 PM

Predictive Value of Polygenic Risk Scores for Coronary Heart Disease in Three Racial/Ethnic Groups

**Ozan Dikilitas** , Daniel J Schaid, Matthew L Kosel, Mayo Clinic, Rochester, MN; Christopher G Chute, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; Gail P Jarvik, Univ of Washington Medical Ctr, Seattle, WA; Joshua C. Denny, Robert J. Carroll, C Michael Stein, Wei-Qi Wei, QiPing Feng, Georgia L Wiesner, Vanderbilt Univ, Nashville, TN; Jennifer A Pacheco, Northwestern Univ Feinberg Sch of Med, Chicago, IL; Ming Ta Michael Lee, Yanfei Zhang, Geisinger Health System, Danville, PA; Alex Fedotov, Columbia Univ Medical Ctr, New York, NY; Hakon Hakonarson, Children's Hosp of Philadelphia, Philadelphia, PA; Amy C Sturm, Marc S Williams, Geisinger Health System, Danville, PA; Patrick M Sleiman, Children's Hosp of Philadelphia, Philadelphia, PA; Teri A Manolio, Natl Human Genome Res Inst, Bethesda, MD; Iftikhar J Kullo, Mayo Clinic, Rochester, MN

2:55 PM

Q&A

3:00 PM

Genome-Wide Association Study of Over One Million Participants Identifies 49 Novel Loci Associated With Coronary Artery Disease

**Krishna G. Aragam** , Massachusetts General Hosp, Boston, MA; Tao Jiang, Univ of Cambridge, Cambridge, United Kingdom; Stavroula Kanoni, Queen Mary Univ, London, United Kingdom; Goel Anuj, Oxford Univ, Oxford, United Kingdom; Brooke Wolford, Ida Surakka, Univ of Michigan, Ann Arbor, MI; Christopher Grace, Univ of Oxford, Oxford, United Kingdom; Gudmar Thorleifsson, DeCODE Genetics, Reykjavik, Iceland; Christopher Nelson, Univ of Leicester, Leicester, United Kingdom; Carolina Roselli, George Hindy, Wallace Wang, Broad Inst, Cambridge, MA; Maria Loreto Munoz Venegas, Univ of Lubeck, Luebeck, Germany; Jemma C Hopewell, Univ Oxford, Oxford, United Kingdom; Christian Ruff, Timi Study Group, Boston, MA; Marc S Sabatine, TIMI Study Group, Boston, MA; Hugh C Watkins, Univ Oxford, Oxford, United Kingdom; John Danesh, Univ of Cambridge, Cambridge, United Kingdom; Patrick Thomas Ellinor, Massachusetts General Hosp, Boston, MA; Hilma Holm, deCODE, Reykjavik, Iceland; Robert J Clarke, NDPH Oxford Univ, Oxford, United Kingdom; Heribert Schunkert, German Heart Ctr, Munich; Martin Farrall, Oxford Univ, Oxford, United Kingdom; Jeanette Erdmann, Univ of Luebeck, Luebeck, Germany; Kari Stefansson, Unnur Thorsteinsdottir, DeCODE Genetics, Reykjavik, Iceland; Cristen Willer, Univ of Michigan, Ann Arbor, MI; Nilesh J Samani, Glenfield Hosp, Leicester, United Kingdom; Panos Deloukas, Queen Mary Univ, London, United Kingdom; Sekar Kathiresan, Massachusetts General Hosp, Boston, MA; Adam Butterworth, Univ of Cambridge, Cambridge; CARDIoGRAMplusC4D – Million Hearts Initiative

3:10 PM

Q&A

# Abstract Oral Session

## HT.AOS.HTP2 - HealthTech Pavilion Abstract Session: There's an App (or Tech Solution) for That: SmartPhones, Wearables and Bringing Care to the People

#### Health Innovation Pavilion, Heart Hub, Science and Technology Hall, Level 2

### Monday, November 18, 2019, 2:00 PM - 2:48 PM

2:00 PM

Moderator

Mintu Turakhia, Palo Alto, CA

2:00 PM

Moderator

Lora E Burke, Pittsburgh, PA

2:00 PM

Fitbit-derived Physical Activity in Atrial Fibrillation Patients

**Sarah Semaan** , Geoffrey H Tison, Gregory Nah, Eric Vittinghoff, Mark J Pletcher, Jeffrey Olgin, Gregory M Marcus, UCSF, San Francisco, CA

2:05 PM

Q&A

2:08 PM

A Feasibility Study to Assess Delivery of Automated External Defibrillators via Drones in Simulated Cardiac Arrest - Users' Experiences and the Human-Drone Interaction

**Jessica K. Zegre-Hemsey** , Mary E. Grewe, Anna Johnson, Univ of North Carolina at Chapel Hill, Chapel Hill, NC; Brittany M. Bogle, Univ of North Carolina-Chapel Hill, Chapel Hill, NC; Evan Arnold, North Carolina State Univ, Raleigh, NC; Wayne D Rosamond, Univ NC Sch Public Hlth, Chapel Hill, NC

2:13 PM

Q&A

2:16 PM

Home Blood Pressure Monitoring Plus a Mobile Phone-Based Hypertension Health Coaching App or a Blood Pressure Tracking App: A Randomized Controlled Clinical Trial

**Stephen D. Persell** , Northwestern Univ, Chicago, IL; Yaw A Peprah, Dawid Lipiszko, Ji Young Lee, Northwestern Univ, Chicgao, IL; Jim Li, Omron Healthcare, Lake Forest, IL; Jody D Ciolino, Northwestern Univ, Chicago, IL; Kunal N Karmali, Northwestern Med, Oak Park, IL; Kevin DeLury, Lark Technologies Inc., Mountain View, CA; Hironori Sato, Omron Healthcare Co., Kyoto, Japan

2:21 PM

Q&A

2:24 PM

First of Its Kind, Cuff-Less, Standalone, Wearable Technology for Continuous, Non-invasive Blood Pressure Monitoring

**Mohan Thanikachalam** , Tufts Univ Sch of Med, Boston, MA; Abhijit Biswas, Dynocardia, Inc, Lowell, MA

2:29 PM

Q&A

2:32 PM

Text Message Medication Adherence Reminders Automated and Delivered at Scale Across Two Institutions: Pilot Testing the "Nudge" System

**Phat Luong** , Joy Waughtal, Univ of Colorado at Denver, Aurora, CO; Thomas J. Glorioso, Veterans Affairs Hosp, Longmont, CO; Lisa M Caputo Sandy, Univ of Colorado at Denver, Aurora, CO; Michael HO, Veterans Affairs Hosp, Aurora, CO; Pamela Peterson, Denver Health Medical Ctr, Denver, CO; Sheana Bull, Colorado Sch of Public Health, Aurora, CO

2:37 PM

Q&A

2:40 PM

Atrial Fibrillation Progression in a Novel Digital Health Cohort

Zohreh Karbaschi, **Jacqueline Shreibati** , Alexander Valys, Daniel Treiman, David E Albert, AliveCor, Inc., Mountain View, CA; Stavros Stavrakis, Univ of Oklahoma, Oklahoma City, OK

2:45 PM

Q & A

# Abstract Oral Session

## NR.AOS.371 - How Physiology Drives Personalized Interventions in CVD

#### 113A

### Monday, November 18, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Quin E Denfeld, Portland, OR

2:00 PM

Gender Differences in Brain Injury in Heart Failure Patients

**Mary A Woo** , UCLA, Los Angeles, CA; Bhaswati Roy, Univ of California, Los Angeles, CA; Gregg C Fonarow, UCLA Medical Ctr, Los Angeles, CA; Rajesh Kumar, Univ of Calif at Los Angeles, Los Angeles, CA

2:10 PM

Q & A

2:15 PM

Dyspnea and Fatigue in Heart Failure: Are They Related to Brain Blood Flow?

**Anna M Klar** , Lisa C Bratzke, Univ of Wisconsin, Madison, WI

2:25 PM

Q & A

2:30 PM

Effect of Ischemic Preconditioning on Apoptosis and Autophagy: A Potential Key Role in ST-Elevation vs. Non-ST Elevation Acute Myocardial Infarction

**Salah S Al-Zaiti** , Omar Abu-Jaradeh, Univ of Pittsburgh, Pittsburgh, PA; Ziad Faramand, Univ of Pittsburgh Medical Ce, Pittsburgh, PA; Imad Al-Ghouleh, Yvette Conley, Univ of Pittsburgh, Pittsburgh, PA

2:40 PM

Q & A

2:45 PM

Novel Techniques to Diagnose Statin-Associated Muscle Symptoms

**Beth Taylor** , Univ of Connecticut, Storrs, CT; Gregory Panza, Hartford Hosp, Hartford, CT; Adam Lepley, Univ of Connecticut, Storrs, CT; Amanda L Zaleski, Paul D Thompson, Hartford Hosp, Hartford, CT

2:55 PM

Q & A

3:00 PM

Racial Differences in Oxidative Stress and Cardiovascular Response After Spironolactone Treatment in Resistant Hypertension

**Brittany Butts** , Emory Univ, Atlanta, GA; David A Calhoun, Univ Alabama at Birmingham, Birmingham, AL; Louis Dell'Italia, Univ of Alabama at Birmingham, Birmingham, AL

3:10 PM

Q & A

# Cardiovascular Seminar

## EA.CVS.1642 - Addressing Essential Gaps in the Care of Patients with Atrial Fibrillation

#### 102AB

### Monday, November 18, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Mina K Chung, Cleveland, OH

2:00 PM

Definition and Prevalence of Silent AF

Lin Yee Y Chen, Minneapolis, MN

2:07 PM

Q&A

2:09 PM

How Does Silent AF Differ from Clinical AF?

Elizabeth Kaufman, Cleveland, OH

2:16 PM

Q&A

2:18 PM

Silent AF and Predictors of Stroke

Jose A Joglar Sr., Dallas, TX

2:25 PM

Q&A

2:27 PM

Atrial Cardiomyopathy, Unexplained Stroke, and Need for Anticoagulation

Mitchell Elkind, New York, NY

2:34 PM

Q&A

2:36 PM

Obesity and Weight Reduction for AF

Lee L Eckhardt, Madison, WI

2:43 PM

Q&A

2:45 PM

Physical Activity - Reducing AF or Too Much of a Good Thing?

Quinn Pack, MA

2:52 PM

Q&A

2:54 PM

Implementation Strategies and Implications for Clinical Practice

Prashanthan Sanders, Adelaide, Australia

3:01 PM

Q&A

3:03 PM

Other Potentially Modifiable Risk Factors: Sleep Apnea, Smoking, Alcohol, and Caffeine

Kevin Trulock, OH

3:10 PM

Q&A

# Cardiovascular Seminar

## CA.CVS.26 - Frontiers in Exosome Biology

#### 119AB

### Monday, November 18, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Douglas Losordo, New York, NY

2:00 PM

Moderator

Doris A Taylor, Houston, TX

2:00 PM

Beyond Exosomes: Mechanism and Function

Phillip Yang, Stanford, CA

2:10 PM

Q&A

2:15 PM

Differential Molecular Cargo of Exosomes

Raj Kishore, Philadelphia, PA

2:25 PM

Q&A

2:30 PM

GMP Manufacturing of Exosomes for Cardiac Therapy

Aisha Khan, Miami, FL

2:40 PM

Q&A

2:55 PM

Q&A

2:45 PM

Dose and Administration of Exosomes

Eduardo Marban, Los Angeles, CA

3:00 PM

Cortical Bone Stem Cells and Paracrine Function

Sadia Mohsin, Philadelphia, PA

3:10 PM

Q&A

# Cardiovascular Seminar

## WS.CVS.228 - Maximizing Talent and Achieving Gender Equity in Our Workforce

#### 112AB

### Monday, November 18, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Edda Spiekerkoetter, Stanford, CA

2:00 PM

Moderator

Catherine P Benziger, Duluth, MN

2:00 PM

Overcoming challenges for women in academic cardiology

Hannah Valantine, Bethesda, MD

2:15 PM

Importance of mentoring and female role models

Judy Regensteiner, Denver, CO

2:30 PM

Practical wisdom for basic scientist

Ronglih Liao, Stanford, CA

2:45 PM

Advancing gender equity within institutions

Nancy Spector

3:00 PM

Enhancing Leadership Opportunities for Women

Emelia J Benjamin, Brookline, MA

# Cardiovascular Seminar

## AT.CVS.304 - Modern Mechanobiology: From Genomics to Discovering Therapeutic Targets

#### 126B

### Monday, November 18, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Alison Marsden, Stanford, CA

2:00 PM

Moderator

Tzung K Hsiai, Los Angeles, CA

2:00 PM

Mechanoregulation of Atherosclerosis and Aortic Valve Calcification

Hanjoong Jo, Atlanta, GA

2:10 PM

Q&A

2:15 PM

Towards New Therapeutic Targets: Genomic and BioMechanical Approaches to Unravel Mechanisms That Control Atherosclerosis

Paul Evans, Sheffield, United Kingdom

2:25 PM

Q&A

2:30 PM

Multi-disciplinary Approaches to Elucidate New Endothelial Mechano-transduction Mechanisms Related to Genome-wide Association Studies (GWAS) of Coronary Artery Disease (CAD)

Yun Fang, Chicago, IL

2:40 PM

Q&A

2:45 PM

Bioengineering Approaches to Understand and Fight Heart Valve Disease

Kathryn Grande Allen, Houston, TX

2:55 PM

Q&A

3:00 PM

Mechanotransductional Signaling Regulates Endothelial Function

Yi Zhu, Tianjin

3:10 PM

Q&A

# Cardiovascular Seminar

## VA.CVS.503 - PVD Workshop: Vascular Jeopardy

#### Game Central

### Monday, November 18, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Umberto Campia, Boston, MA

# Cardiovascular Seminar

## CA.CVS.249 - RNA-Based Regulation of Cardiac Remodeling

#### 120C

### Monday, November 18, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Saumya DAS, Boston, MA

2:00 PM

Moderator

Da-zhi Wang, Boston, MA

2:00 PM

Long Non-coding RNAs in Heart Disease

Yibin Wang, Los Angeles, CA

2:13 PM

Q & A

2:18 PM

Localized RNA Translation in Cardiomyocytes

Izhak Kehat, Haifa, Israel

2:31 PM

Q & A

2:36 PM

mRNA Processing and Splicing in the Stressed Heart

Auinash Kalsotra, Urbana, IL

2:49 PM

Q & A

2:54 PM

RNA Modifications in Cardiac Homeostasis and Disease

Susmita SAHOO, New York, NY

3:09 PM

Q & A

# Cardiovascular Seminar

## AC.CVS.79 - State (and the Art) of the Cardiac Intensive Care Unit (CICU)

#### 103A

### Monday, November 18, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Jeffrey Kuvin, Lebanon, NH

2:00 PM

Moderator

Shashank Sinha, Falls Church, VA

2:00 PM

State (and the Art) of the Cardiac Intensive Care Unit (CICU)

David Morrow, Boston, MA

2:11 PM

Intensivists Should Staff the Contemporary CICU (Debate)

Sean van Diepen, Edmonton, AB, Canada

2:33 PM

Evolving Graduate Medical Education Paradigms for CICU Training

Jessica Fleitman, Philadelphia, PA

2:44 PM

Developing Quality and Safety Initiatives in the CICU

Shashank Sinha, Falls Church, VA

2:55 PM

Building a Career as an Academic Investigator in the CICU

Erin Bohula May, Boston, MA

3:06 PM

Discussion

# Council Sponsored Activities

## CSA.18 - Genomic and Precision Medicine and Epidemiology Mi-Career Research Award and Lecture

#### Pennsylvania Convention Center, Room 121 C

### Monday, November 18, 2019, 2:00 PM - 2:30 PM

This is not a CME/CE certified session

# Frontiers in Science

## AT.FIS.340 - Frontiers in Thrombosis: Clinical Challenges in Thrombosis

#### 126A

### Monday, November 18, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Leslie Skeith, Calgary, AB, Canada

2:00 PM

Moderator

Steven R Lentz, Iowa City, IA

2:00 PM

High Risk Acquired Thrombophilias (APS, Hit)

Leslie Skeith, Calgary, AB, Canada

2:10 PM

Q&A

2:15 PM

DOACs: Not Just for Venous Thrombosis

Andrea T Obi, Ann Arbor, MI

2:25 PM

Q&A

2:30 PM

The Challenge of Thrombosis Prevention With Mechanical Circulation Devices

Lisa Baumann Kreuziger, Wauwatosa, WI

2:40 PM

Q&A

2:55 PM

Q&A

3:00 PM

Should We Use DOACs in Obese Patients?

Karlyn Martin, Chicago, IL

3:10 PM

Q&A

# Main Event

## CS.ME.1641 - Trending Topics in Population Science

#### Nutter Theatre

### Monday, November 18, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Amit Khera, Dallas, TX

2:00 PM

Moderator

Norrina B Allen, Chicago, IL

2:10 PM

Trending Topics in Quality of Care and Outcomes

Larry A Allen, Aurora, CO

2:30 PM

Trending Topics in Women & Special Populations

Kathryn M Rexrode, Boston, MA

2:40 PM

Trending Topics in Cardiometabolic Health and Diabetes

Prakash C Deedwania II, Fresno, CA

3:00 PM

Lay Stakeholder

James Lewis Young II, Detroit, MI

3:05 PM

Q&A

# Main Event

## CS.ME.101 - Trending Topics: Clinical Science

#### Main Event II

### Monday, November 18, 2019, 2:00 PM - 3:15 PM

2:00 PM

Moderator

Hani Jneid, Houston, TX

2:00 PM

Moderator

Elaine Hylek, BOSTON, MA

2:00 PM

Acute Coronary Syndromes

Venu Menon, Cleveland, OH

2:10 PM

Heart Failure and Cardiomyopathies

Mark H Drazner, Dallas, TX

2:20 PM

Hypertension and Nephrology

Zhongjie SUN, Memphis, TN

2:30 PM

Stroke

Sameer A Ansari, Chicago, IL

2:50 PM

Interventional Treatments

Jacqueline E Tamis-Holland, New York, NY

3:00 PM

Pulmonary Hypertension and Critical Care

Paul B Yu, Boston, MA

# Abstract Rapid Fire Oral

## EP.RFO40 - Epidemiology of Vascular Diseases: Thinking Outside the Heart

#### Science and Technology Hall A, Booth 605, Level 2

### Monday, November 18, 2019, 2:05 PM - 2:55 PM

2:05 PM

Moderator

Parag H Joshi, Dallas, TX

2:05 PM

Sex Differences in Operative Outcomes and Mortality for Type A Acute Aortic Dissection: A Study From the International Registry of Acute Aortic Dissection Interventional Cohort

**Lauren V Huckaby** , Univ of PIttsburgh Medical Ctr, Pittsburgh, PA; Ibrahim Sultan, Univ of Pittsburgh, Pittsburgh, PA; Santi Trimarchi, IRCCS Policlinico San Donato, Cardiovascular Ctr, San Donato Milanese, Italy; Bradley G Leshnower, Emory Univ Sch of Med, Atlanta, GA; Edward P Chen, Emory Univ, Atlanta, GA; Derek Brinster, Northwell Health, New York; Truls Myrmel, The Arctic Univ of Norway, Breivika, Norway; Anthony L Estrera, UT Medical Sch Houston, Houston, TX; Daniel G Montgomery, Univ of Michigan, Ann Arbor, MI; Amit Korach, Hadassah Hebrew university Medical, jerusalem, Israel; Hans-Henning Eckstein, Technical Univ of Munich, Munich, Germany; Joseph S Coselli, Baylor Coll of Med, Houston, TX; Takeyoshi Ota, The Univ of Chicago, Chicago, IL; Clayton Kaiser, Vanderbilt Univ Medical Cente, Nashville, TN; Kim Eagle, Univ of Michigan, Ann Arbor; Himanshu J Patel, Univ Michigan Health System, Ann Arbor, MI; Thomas G Gleason, UPMC Shadyside, Pittsburgh, PA

2:10 PM

Q & A

2:15 PM

Role of Thoracic Aortic Calcification for the Prediction of All-Cause and Cardiovascular Disease Mortality: The Coronary Artery Calcium Consortium

**Sina Kianoush** , Yale Univ, Watebury, CT; S M Iftekhar Uddin, Johns Hopkins Hosp, Baltimore, MD; Albert Danso Osei, Johns Hopkins Sch of Med, Baltimore, MD; Hassan Mirbolouk, Olusola Orimoloye, Omar Dzaye, Johns Hopkins Univ, Baltimore, MD; Michael D Miedema, Minneapolis Heart Insti, Minneapolis, MN; Leslee J Shaw, Emory Univ, Atlanta, GA; John A Rumberger, The Princeton Longevity Ctr, Hopewell, NJ; Daniel Berman, The Princeton Longevity Ctr, Hopewell, NJ, Los Angeles, CA; Matthew J Budoff, Los Angeles Biomedical Researc, Torrance, CA; Alan Rozanski, Los Angeles Biomedical Researc, Torrance, CA, New York, NY; Khurram Nasir, Baptist Health South Florida, New Haven, CT; Michael J Blaha, Johns Hopkins Hosp, Baltimore, MD

2:20 PM

Q & A

2:25 PM

Low Density Lipoprotein Aggregation is Increased and Predictive of Major Adverse Cardiovascular Events in Patients With Peripheral Artery Disease Undergoing Lower Extremity Revascularization

**Sean P Heffron** , NYU Sch Med, New York, NY; Maija K Ruuth, Wihuri Res Inst, Helsinki, Finland; Gustavo Hernandez, New York Univ, New York, NY; Crystalann Rodriguez, NYU Sch Med, New York, NY; Katariina Oorni, Wihuri Res Inst, Helsinki, Finland; Jeffrey S Berger, New York Univ Sch Med, New York, NY

2:30 PM

Q & A

2:35 PM

Burden of Peripheral Artery Disease and Incident CVD and Mortality

**Jonathan Unkart** , Univ of California San Diego, La Jolla, CA; Michael H Criqui, UCSD, La Jolla, CA; Maria Rosario G Araneta, Univ of California San Diego, La Jolla, CA; Joachim H IX, Univ of California San Diego, San Diego, CA; Kunihiro Matsushita, Johns Hopkins Univ, Baltimore, MD; Matthew A Allison, Univ of California San Diego, La Jolla, CA

2:40 PM

Q & A

2:45 PM

Vitamin C Modulates Risk of Peripheral Arterial Disease in Smokers: Results From NHANES 2003-2004

Guangzhi Cong, **Ulka Sachdev** , UPMC, Pittsburgh, PA

2:50 PM

Q & A

# Abstract Rapid Fire Oral

## GE.RFO31 - Epigenetic Regulation of Cardiovascular Disease

#### Zone 1, Science and Technology Hall

### Monday, November 18, 2019, 2:05 PM - 2:55 PM

2:05 PM

Moderator

Sarah Franklin, Salt Lake Cty, UT

2:05 PM

A Novel Role of Genome-Wide DNA Methylation as a Regulator of Cardiac Gene Expression in End-stage Human Heart Failure

**Mark E Pepin** , Chae-Myeong Ha, Univ of Alabama at Birmingham, Birmingham, AL; Stavros Drakos, Martin Tristani-Firouzi, Craig Selzman, Univ of Utah, Salt Lake City, UT; James C. Fang, Univ of Utah, Salt Lake Utah, UT; Adam R Wende, Univ of Alabama at Birmingham, Birmingham, AL; Omar Wever-Pinzon, Univ of Utah, Salt Lake City, UT

2:10 PM

Q & A

2:15 PM

Clonal Hematopoiesis of Indeterminate Potential Associates With Pro-Inflammatory Circulating Blood Cell Phenotypes and Confers Worse Prognosis in Patients With Degenerative Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Replacement

**Silvia Mas-Peiro** , Jedrzej Hoffmann, Michael Rieger, Stephan Fichtlscherer, Univ Hosp Frankfurt, Frankfurt am Main, Germany; Stefanie Dimmeler, Inst of Cardiovascular Regeneration, Frankfurt am Main, Germany; Mariuca Vasa-Nicotera, Andreas M Zeiher, Univ Hosp Frankfurt, Frankfurt am Main, Germany

2:20 PM

Q & A

2:25 PM

Fto-mediated RNA Demethylation Regulates Cardiac Contractile Protein Expression And Function

**Prabhu Mathiyalagan** , Marta Adamiak, Morad Asadi, Joshua Mayourian, Yassine Sassi, Yaxuan Liang, Neha Agarwal, Divya Jha, Shihong Zhang, Erik Kohlbrenner, Elena Chepurko, Icahn Sch of Med at Mount Sinai, New York, NY; Xiaoke Yin, Kings Coll London, London, United Kingdom; Jiqiu Chen, Mount Sinai Sch Med, New York, NY; Maria Giovanna Trivieri, Mount Sinai, New York, NY; Rihab Bouchareb, CVRC, New York, NY; Rajvir Singh, Icahn Sch of Med, New York, NY; Kenneth M Fish, Mount Sinai, New York, NY; Kiyotake Ishikawa, Icahn Sch of Med at Mount Sinai, New York, NY; Manuel Mayr, Kings Coll London, London, United Kingdom; Djamel Lebeche, Mount Sinai Sch of Med, New York, NY; Roger Joseph Hajjar, Mount Sinai Cardiovascular Res, New York, NY; Susmita Sahoo, Mount Sinai Sch of Med, New York, NY

2:30 PM

Q & A

2:40 PM

Q & A

2:45 PM

Sex Based Mhrt Methylation

Harikrishnan KN, Jun Okabe, Monash Univ, Melbourne, Australia; Prabhu Mathiyalagan, Icahn Sch of Med at Mount S, New York, NY; Sameer Jadaan, Gulcan Sarila, Mark Ziemann, Scott Maxwell, Ishant Khurana, Monash Univ, Melbourne, Australia; Xiao-Jun Du, Baker IDI Heart Diabetes Inst, Melbourne, Australia; **Assam El-Osta** , Monash Univ, Melbourne, Australia

2:50 PM

Q & A

# Abstract Rapid Fire Oral

## IN.RFO34 - Interventional Cardiologists on Fire

#### Zone 2, Science and Technology Hall

### Monday, November 18, 2019, 2:05 PM - 2:55 PM

2:05 PM

Moderator

Manesh R Patel, Durham, NC

2:05 PM

Periprocedural Predictors of New-Onset Conduction Abnormalities After Transcatheter Aortic Valve Replacement

**Kensuke Matsushita** , Mickael Ohana, Benjamin Marchandot, Marion Kibler, Joe Heger, Marilou Peillex, Antonin Trimaille, Sebastien Hess, Lelia Grunebaum, Antje Reydel, Laurence Jesel, Olivier Morel, Patrick Ohlmann, Nouvel Hôpital Civil, Strasbourg, France

2:15 PM

**P2Y** 12 **Inhibition by Clopidogrel Increases Periprocedural Bleeds in Patients Undergoing Transcatheter Aortic Valve Replacement**

**Kensuke Matsushita** , Benjamin Marchandot, Marion Kibler, Joe Heger, Marilou Peillex, Antonin Trimaille, Sebastien Hess, Lelia Grunebaum, Mickael Ohana, Antje Reydel, Laurence Jesel, Patrick Ohlmann, Olivier Morel, Nouvel Hôpital Civil, Strasbourg, France

2:25 PM

Transcatheter Pulmonary Valve Implantation: A 10-year Single Center Experience

Witold Ruzyllo, **Elzbieta K Biernacka** , Olgierd Wozniak, Miroslaw Kowalski, Mateusz Spiewak, Aleksander Szczesny, Krzysztof Weronski, Slawomir Banas, Hanna Siudalska, Jacek Rozanski, Mariusz Kusmierczyk, Piotr Hoffman, Marcin Demkow, Inst of Cardiology, Warsaw, Poland

2:35 PM

Patient Characteristics and Gender Disparities Among Patients With Non-Valvular Atrial Fibrillation Treated With Watchman Device

**Krunalkumar Patel** , Saint Mary Medical Ctr, Langhorne, PA; Kirtenkumar Patel, North Shore Univ Hosp, Manhasset, NY; Amitkumar Patel, Northshore Univ Hosp, Manhasset, NY; Nirav Patel, Hartford Hosp, Hartford, CT; Rajkumar Prakashbhai Doshi, Univ of Nevada Reno SOM, Reno, NV; Perwaiz Meraj, North Shore Univ Hosp, Manhasset, NY

2:45 PM

Phenotypes of Cardiogenic Shock Associated With Increasing In-Hospital Mortality: A Report From The National Cardiogenic Shock Working Group Registry

**Katherine Thayer** , Tufts Medical Ctr, Bosotn, MA; Sarah Newman, Tufts Medical Ctr, Boston, MA; Mohyee Ayouty, Lena Jorde, Tufts Medical Ctr, Boston; Reshad Garan, Beth Israel, Boston, MA; Jaime Hernandez Montfort, UTMB, Galveston, TX; Claudius Mahr, Medical Coll Wisconsin, Milwaukee, WI; Detlef Wencker, Baylor Univ Medical Ctr, Overland Park, KS; Shashank Shekhar Sinha, INOVA Heart and Vascular Inst, Falls Church, VA; Esther Vorovich, Northwestern, Wilmette, IL; Jacob Abraham, Providence Heart Inst, Portland, OR; William O'Neill, Henry Ford Hosp, detroit, MI; Daniel Burkhoff, Cardiovascular Res Fndn, New York, NY; Navin K Kapur, Tufts Medical Ctr, Boston, MA

# Abstract Rapid Fire Oral

## HF.RFO37 - Pharmacological Therapy in HF/Cardiomyopathy: The Next Important Indication or Agent?

#### Zone 4, Science and Technology Hall

### Monday, November 18, 2019, 2:05 PM - 2:55 PM

2:05 PM

Precision Pharmacological Treatment for Obstructive Hypertrophic Cardiomyopathy With Mavacamten: One-Year Results From PIONEER-OLE

**Stephen B Heitner** , Knight Cardiovascular Inst, Oregon Health & Sciences Univ, Portland, OR; Steven Lester, Mayo Clinic Arizona, Phoenix, AZ; Andrew Wang, Duke Health Ctr at Southpoint, Durham, NC; Sheila M Hegde, Brigham and Women's Hosp, Boston, MA; Liang Fang, Ganesh Balaratnam, Amy J Sehnert, MyoKardia, Inc., South San Francisco, CA; Daniel Jacoby, Yale Univ Sch of Med, New Haven, CT

2:15 PM

MYK-491, a Novel Small-Molecule Cardiac Myosin Activator Increases Cardiac Systolic Function and Preserves Mechanical Efficiency: Pre-Clinical in vivo and in vitro Evidence

Sarah Fernandes, Angelos Oikonomopoulos, Sarah K Jimenez-MacInnes, Myokardia, San Francisco, CA; Roozbeh Aschar-Sobbi, TARA Biosystems, New York, NY; Marcus Henze, Marius Sumandea, Qing-Fen Gan, Robert L Anderson, **Carlos L del Rio** , Myokardia, San Francisco, CA

2:25 PM

Early Reduction in Elevated Pulmonary Artery Pressures After Initiation of Sacubitril/valsartan: Insights From Ambulatory Hemodynamic Monitoring

**Akshay S Desai** , Brigham Womens Hosp, Boston, MA; J. Thomas Heywood, Scripps Clinic, La Jolla, CA; Lisa Rathman, The Heart Group of Lancaster General Health, Lancaster, PA; William T Abraham, OHIO STATE UNIVERSITY, Columbus, OH; Philip Adamson, Marie-Elena Brett, Abbott Labs, Austin, TX; Maria R Costanzo, Advocate Medical Group, Downers Grove, IL; Nirav Raval, Advent Health Transplant Inst, Orlando, FL; David Shavelle, Univ of Southern California, Los Angeles, CA; Poornima Sood, Abbott Labs, Austin, TX; Lynne Warner Stevenson, Vanderbilt Univ Medical Cente, Nashville, TN

2:35 PM

Efficacy and Safety of Sacubitril/Valsartan in Acute Decompensated Heart Failure in High-Risk Patients in the PIONEER-HF Trial

**David D Berg** , Brigham and Women's Hosp, Boston, MA; Eric J Velazquez, Yale Univ Sch of Med, New Haven, CT; Carol I Duffy, Novartis Pharmaceuticals, Cambridge, MA; Yared Gurmu, Eugene Braunwald, David A Morrow, Brigham and Women's Hosp, Boston, MA

2:45 PM

The Effect of the Cardiac Myosin Activator, Omecamtiv Mecarbil, on Diastolic Filling and Function in Chronic Systolic Heart Failure (COSMIC-HF)

**Tor Biering-Sørensen** , Herlev and Gentofte Hosp, Copenhagen, Denmark; John R Teerlink, San Francisco VAMC UCSF, San Francisco, CA; Masatoshi Minamisawa, Shinshu Univ Sch of Med, Matsumoto, Japan; Gary Michael Felker, Duke, Durham, NC; John J McMurray, BHF Cardiovascular Res Ctr, Glasgow, United Kingdom; Fady Malik, Cytokinetics Inc., S San Fran, CA; Steven Robert Goldsmith, Hennnepin County Medical Ctr, Minneapolis, MN; Christopher Kurtz, 1 Amgen Ctr Drive, Thousand Oaks, CA; Scott Solomon, Brigham and Women's Hosp, Boston, MA

# Moderated Digital Posters

## AT.MDP63 - Angiogenesis and Arteriogenesis

#### Moderated Posters 5, Science and Technology Hall

### Monday, November 18, 2019, 2:05 PM - 2:55 PM

2:05 PM

Development Of An Advanced Injectable Therapy For Ischemic Vascular Disease

**Andrew Sligar** , The Univ of Texas at Austin, Austin, TX; Gretchen Howe, Univ of Texas McGovern Medical Sch, Houston, TX; Julia Goldman, UT Health Science Ctr at Houston, Houston, TX; Patricia Felli, Univ of Texas McGovern Medical Sch, Houston, TX; Almudena Gomez-Hernandez, Varsha Karanam, The Univ of Texas at Austin, Austin, TX; Richard W Smalling, Univ Texas Med Sch Houst, Houston, TX; Aaron B Baker, Univ of Texas at Austin, Austin, TX

2:10 PM

Q & A

2:15 PM

Endothelial Alpha Hemoglobin is a Nitrite Reductase

**Thomas C S Keller IV** , Alexander S Keller, Univ of Virginia Sch of Med, Charlottesville, VA; Steven Brooks, Natl Inst of Allergy and Infectious Diseases, Rockville, MD; Rakesh P. Patel, Univ of Alabama at Birmingham, Birmingham, AL; Linda Columbus, Univ of Virginia, Charlottesville, VA; Miriam Cortese-Krott, Heinrich Heine Univ, dusseldorf; Hans Ackerman, Natl Inst of Allergy and Infectious Diseases, Rockville, MD; Brant E Isakson, Univ of Virginia Sch of Med, Charlottesville, VA

2:20 PM

Q & A

2:25 PM

Elevated Calcium Drives Ischemia-Induced Angiogenesis

**Jocelyne Mulangala** , Emma Akers, Emma L Solly, Univ of Adelaide, SAHMRI, Adelaide, Australia; Panashe M Bamhare, Laura A Wilsdon, SAHMRI, Adelaide, Australia; Joanne Tsui Ming Tan, SAHMRI, Adelaide, SA, Australia; Stephen J Nicholls, Monash Universty, Melbourne, Australia; Belinda A DiBartolo, Univ of Sydney, Royal Northshore Hosp, Sydney, Australia

2:30 PM

Q & A

2:35 PM

**A Novel Long Noncoding RNA** LncAng **Promotes Angiogenesis Through SNF5-Mediated GDF6 Expression**

**Rongrong Wu** , Wangxing Hu, Jinghai Chen, Xinyang Hu, Jian'an Wang, Zhejiang Univ, Hangzhou, China

2:40 PM

Q & A

2:45 PM

Relationship of Hdl-associated Cholesterol Efflux Capacity to Coronary Collateralization In Diabetic and Non-diabetic Patients With Stable Angina and Chronic Total Occlusion

**Xiao Qun Wang** , Ying Shen, Jia Wei Chen, Xin Yi Shu, Chang Li, Chen Die Yang, Lin Lu, Feng Hua Ding, Zhen Kun Yang, Rui Yan Zhang, Wei Feng Shen, Ruijin Hosp, Shanghai Jiao-Tong Univ Sch of Med, Shanghai, China

2:50 PM

Q & A

# Moderated Digital Posters

## IM.MDP57 - Feel the Rhythm: Echocardiography of Arrhythmia

#### Moderated Posters 3, Science and Technology Hall

### Monday, November 18, 2019, 2:05 PM - 2:55 PM

2:05 PM

Moderator

Carlos Jose Rodriguez, Bronx, NC

2:05 PM

Prediction of Left Atrial Appendage Blood Flow Velocity by Brain-type Natriuretic Peptide and CHA2DS2-VASc Score in Patients With Atrial Fibrillation

**Katsuomi Iwakura** , Atsunori Okamura, Yasushi Koyama, Koichi Inoue, Mutsumi Iwamoto, Satoshi Watanabe, Hiroyuki Nagai, Yuko Hirao, Koji Tanaka, Sakurabashi Watanabe Hosp, Osaka, Japan; Toshinari Onishi, Japan; Takafumi Oka, Nobuaki Tanaka, Masato Okada, Akinori Sumiyoshi, Kota Tanaka, Sakurabashi Watanabe Hosp, Osaka, Japan; Ryo Kitagaki, Sakurabashi Watanabe Hosp, Osaka city, Japan; Masato Ishikawa, Sakurabashi Watanabe Hosp, Osaka, Japan; Issei Yoshimoto, Sakurabashi Watanabe Hosp, OSAKA, Japan; Satoshi Suzuki, Hirokazu Tanaka, Kenshi Fujii, Sakurabashi Watanabe Hosp, Osaka, Japan

2:10 PM

Q & A

2:15 PM

Discordance Between Electrocardiograph Rhythm and Atrial Appendage Doppler Wave Form Phenotype Predicts Post Cardiac Surgery Atrial Fibrillation: A Prospective Intraoperative Study

**Qizhe Cai** , Beth Israel Deaconess Medical Ctr, Boston, MA; Akiva Nachshon, Beth Israel Deaconess Medical Ctr, Jerusalem, Israel; Jason D Matos, Beth Israel Deaconess, Boston, MA; Feroze Mahmood, Beth Israel Deaconess Medical, Sharon, MA; Adam Lerner, BIDMC Dept of Anesthesia, Boston, MA; John Mitchell, Beth Israel Deaconess Medical Ctr, Boston; Ariel Mueller, Warren J Manning, Beth Israel Deaconess Medical Ctr, Boston, MA

2:20 PM

Q & A

2:25 PM

Risk Factors for Atrial Fibrillation in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation

Ellen Chang, Jennifer Teh, Kelly Peng, Heeyoung Kim, Ryotaro Nakamura, Stephen Forman, Kalyanasundaram Venkararaman, Saro Armenian, **LiYing Cai** , City of Hope, Duarte, CA

2:30 PM

Q & A

2:35 PM

Ventricular Arrhythmias in Mitral Valve Prolapse: Identification of Clinical and Echocardiographic Associates

**Aniek L Van Wijngaarden** , Marta de Riva Silva, Yasmine L Hiemstra, Jeroen J Bax, Victoria Delgado, Nina Ajmone Marsan, Leiden Univ Medical Ctr, Leiden, Netherlands

2:40 PM

Q & A

2:45 PM

Sudden Arrhythmic Death Is Associated With Lower Global Longitudinal Strain and Longer Mechanical Dispersionin the San Francisco Postmortem Systematic Investigation of Sudden Cardiac Death (POST SCD) Study

**Satvik Ramakrishna** , Dwight Bibby, Eric Vittinghoff, Annie Bedigian, Joanne Probert, Lisa Lim, Jeffrey Olgin, Philip Ursell, Ellen Moffatt, Zian H Tseng, Francesca Nesta Delling, Univ of California San Francisco, San Francisco, CA

2:50 PM

Q & A

# Moderated Digital Posters

## WS.MDP69 - Female Specific Risk Factors for CVD

#### Moderated Posters 7, Science and Technology Hall

### Monday, November 18, 2019, 2:05 PM - 2:55 PM

2:10 PM

Q & A

2:15 PM

Natural and Surgical Menopause Before Age 40 Are Associated With Long-Term Incident Cardiovascular Disease Risk

**Michael Honigberg** , Massachusetts General Hosp, Boston, MA; Seyedeh Maryam Zekavat, Yale Sch of Med, Newton, MA; Krishna Aragam, Massachusetts General Hosp, Cambridge, MA; Derek Klarin, Nandita Scott, Pradeep Natarajan, Massachusetts General Hosp, Boston, MA

2:20 PM

Q & A

2:25 PM

Family History of Premature Myocardial Infarction Modifies the Association Between Bilateral Oophorectomy and Heart Disease Mortality in a National Cohort of Postmenopausal Women

**Duke Appiah** , Texas Tech Univ Health Sciences Ctr, Lubbock, TX; Chike C Nwabuo, Johns Hopkins Univ, Baltimore, MD; Damilola R. Owoade, Jaffer Samad, Texas Tech Univ Health Sciences Ctr, Lubbock, TX; Imo Ebong, Univ of Chicago, Chicago, Chicago, IL; Stephen Winters, Univ of Louisville, Louisville, KY

2:30 PM

Q & A

2:35 PM

Associations Between Menopause, Cardiac Remodeling, and Diastolic Function: The Coronary Artery Risk Development in Young Adults (CARDIA) Study

**Wendy Ying** , Johns Hopkins Univ Sch of Med, Baltimore, MD; Wendy S Post, Johns Hopkins Univ, Baltimore, MD; Erin D Michos, Johns Hopkins Sch of Med, Baltimore, MD; Vinita Subramanya, Emory Rollins SPH, Atlanta, GA; Pamela Ouyang, Chiadi Ericson Ndumele, Johns Hopkins Univ, Baltimore, MD; Henrique Vasconcellos, Bharath Ambale-Venkatesh, Chike Nwabuo, Johns Hopkins Univ Sch of Med, Baltimore, MD; Donald M Lloyd-Jones, Northwestern Univ, Chicago, IL; Pamela Schreiner, Univ Minnesota, Minneapolis, MN; Jared P Reis, Natl Heart Lung Blood Inst, Bethesda, MD; Cora E Lewis, Univ Alabama Birmingham, Birmingham, AL; Stephen Sidney, Kaiser Permanentr Medical Care, Oakland, CA; Joao A Lima, Dhananjay Vaidya, Johns Hopkins Univ, Baltimore, MD

2:40 PM

Q & A

2:45 PM

Associations of Maternal Cardiovascular Health in Pregnancy With Offspring Cardiovascular Health in Childhood: The Hyperglycemia and Adverse Pregnancy Outcome Follow up Study

**Amanda Marma Perak** , Nicola Lancki, Alan Kuang, Darwin R Labarthe, Northwestern Univ, Chicago, IL; Svati H Shah, Duke Univ, Durham, NC; Lynn P Lowe, Denise M Scholtens, William L Lowe Jr, Donald M Lloyd-jones, Northwestern Univ, Chicago, IL; for the HAPO Follow-Up Study Cooperative ResearchGroup

2:50 PM

Q & A

# Moderated Digital Posters

## HF.MDP51 - Hot Topics in LVAD and Cardiac Transplant

#### Moderated Posters 1, Science and Technology Hall

### Monday, November 18, 2019, 2:05 PM - 2:55 PM

2:05 PM

Heart Failure Therapies and Survival for Patients With Left Ventricular Assist Devices

**Megan McCullough** , Cesar Caraballo, Yale Univ Sch of Med, New Haven, CT; Neal Ravindra, Yale Univ, New Haven, CT; Elliott Miller, Catherine Mezzacappa, Andrew Levin, Jadry Gruen, Samuel Reinhardt, Tariq Ahmad, Nihar R. Desai, Yale Univ Sch of Med, New Haven, CT

2:10 PM

Q & A

2:15 PM

**Improvement in Cognitive Function After Heart Transplant and Mechanical Circulatory Support: Findings From the Sustaining Quality of Life of the Aged (** Sustain-it **) Study**

**Esther Vorovich** , Adin-Cristian Andrei, Northwestern Univ, Chicago, IL; Yao Xu, Andrew Kao, Mid America Heart Inst, Kansas City, MO; Eileen M Hsich, Cleveland Clinic Fndn, Cleveland, OH; Mary Amanda Dew, Univ of Pittsburgh, Pittsburgh, PA; Robert L Kormos, Univ Pittsburgh Medical Ctr, Pittsburgh, PA; Duc Thinh Pham, Northwestern Memorial Hosp, Chicago, IL; Clyde W Yancy Jr., Shane LaRue, Northwestern Univ, Chicago, IL; Michael G Petty, Univ of Minn Med Ctr, Richfield, MN; William Cotts, Advocate Christ Medical Ctr, LaGrange, IL; Salpy Pamboukian, Univ of Alabama at Birmingham, Birmingham, AL; Francis D Pagani, Univ Michican Cardiovasc Ctr, Ann Arbor, MI; Brent Lampert, Ohio State Univ Wexner Medical Ctr, Columbus, OH; Maryl R Johnson, Univ Wisconsin Madison, Madison, WI; Margaret A Murray, Univ of Wisconsin Hosp, Madison, WI; Koji Tekeda, Columbia Univ, New York City, NY; Melana Yuzefpolskaya, Columbia Univ Medical Ctr, New York, NY; Scott Silvestry, Florida Hosp, Orlando, FL; John Spertus, Mid America Heart Inst, Kansas City, MO; James K Kirklin, Univ Alabama Birmingham, Birmingham, AL; Craig Collum, Univ of Alabama at Birmingham, Birmingham, AL; Kathleen Grady, tbd, tbd, KS

2:20 PM

Q & A

2:25 PM

Assessment of Frailty in Patients With Advanced Heart Failure Before and After LVAD Implantation

Cassandra Heaney, Ravi K Vuthoori, **Gregory Gibson** , Donald and Barbara Zucker Sch of Med at Hofstra/Northwell, Manhasset, NY; Edmund Miller, Feinstein Inst for Medical Res, Manhasset, NY; Harold Fernandez, Brian Lima, James Taylor, Kathleen Davidson, North Shore Univ Hosp, Manhasset, NY; Kevin F Kennedy, Mid America Heart Inst, Kansas City, MO; David T Majure, Gerin R Stevens, Simon Maybaum, Donald and Barbara Zucker Sch of Med at Hofstra/Northwell, Manhasset, NY

2:30 PM

Q & A

2:35 PM

**Digoxin Reverses Angiogenic Switch During LVAD Support by Inhibiting the Hypoxia Triggered HIF1-α Signaling Cascade:** In vivo **and** in vitro **Evidence**

**Sasa Vukelic** , Montefiore Medical Centar AECOM, Bronx, NY; Snehal R Patel, Montefiore MC, AECOM, Bronx, NY; Peter P Vlismas, Montefiore Medical Ctr, Bronx, NY; Holly C Williams, Emory Univ Sch of Med, Atlanta, GA; Alejandra San Martin, Emory Univ, Atlanta, GA; Nicholas Sibinga, Albert Einstein Col of Med, Bronx, NY; Thiru Chinnadurai, Montefiore Medical Ctr, Bronx, NY; Daniel B Sims, Montefiore Medical Ctr, New York, NY; Omar Saeed, Daniel J Goldstein, Montefiore Medical Ctr, Bronx, NY; Ulrich P Jorde, Montefiore / Einstein, Bronx, NY

2:40 PM

Q & A

2:45 PM

Right Ventricular Longitudinal Function in Patients on Left Ventricular Assist Device Decreases Despite Inotrope Administration

**Peter Huntjens** , Washington Univ in St. Louis, St Louis, MO; Maria Karmpalioti, Washington Univeristy in St. Louis, St. Louis, MO; Yuko Soyama, Washington Univ in St. Louis, Saint Louis, MO; David Raymer, Barnes Jewish Hosp, St. Louis, MO; Shane LaRue, Washington Univ Sch Of Med, St. Louis, MO; Akinobu Itoh, Washington Univ Sch of Med, Saint Louis, MO; Justin M Vader, Washington Univ, Saint Louis, MO; John Gorcsan III, Washington Univ in St. Louis, Saint Louis, MO

2:50 PM

Q & A

# Moderated Digital Posters

## GE.MDP66 - Large-Scale Biobanks and Whole-Genome Sequencing Studies

#### Moderated Posters 6, Science and Technology Hall

### Monday, November 18, 2019, 2:05 PM - 2:55 PM

2:05 PM

Monogenic and Polygenic Contributions to Atrial Fibrillation Risk: Results From a National Biobank

**Seung Hoan Choi** , Sean J Jurgens, Broad Inst of MIT and Harvard, Cambridge, MA; Steven A Lubitz, Patrick T Ellinor, Massachusetts General Hosp, Boston, MA

2:10 PM

Q & A

2:15 PM

Interplay Between Lifestyle Factors and Genetic Risk for Coronary Heart Disease: A Cohort Study Among Over 51 000 Individuals

**Carlos Iribarren** , Meng Lu, Kaiser Permanente, Oakland, CA; Roberto Elosua, Fund Inst Mar Dinvestigacions Med, Barcelona, Spain; Jamal S Rana, Kaiser Permanente, Oakland, CA

2:20 PM

Q & A

2:25 PM

Genetic Analysis of Ideal Cardiovascular Health in the Veterans Administration Million Veteran Program

**Rose DL Huang** , Xuan-Mai T Nguyen, Luc Djousse, Kelly Cho, J. Michael Gaziano, VA Boston Healthcare System, Boston, MA; Peter Wilson, Atlanta VAMC, Decatur, GA; Jennifer E Huffman, Christopher J O'Donnell, VA Boston Healthcare System, Boston, MA

2:30 PM

Q & A

2:35 PM

Multi-ancestry Whole Genome Sequencing Analysis of Coronary Artery Calcification

**Paul S de Vries** , Sch of Public Health, UTHealth at Houston, Houston, TX; Matthew P Conomos, Deepti Jain, Univ of Washington, Seattle, WA; Michael R Brown, Sch of Public Health, UTHealth at Houston, Houston, TX; Sharon M Lutz, Harvard Medical Sch and Harvard Pilgrim Health Care Inst, Boston, MA; Lawrence F Bielak, Sch of Public Health, Univ of Michigan, Ann Arbor, MI; James G Terry, Vanderbilt Univ Medical Ctr, Nashville, TN; Joshua C Bis, Univ of Washington, Seattle, WA; Nicholette D Palmer, Wake Forest Sch of Med, Winston-Salem, NC; Kent D Taylor, Los Angeles Biomedical Res Inst at Harbor-UCLA, Torrance, CA; Lewis C Becker, Johns Hopkins Univ Sch of Med, Baltimore, MD; Adolfo Correa, Univ of Mississippi Medical Ctr, Jackson, MS; L. Adrienne Cupples, Boston Univ Sch of Public health and the Framingham Heart Study, Boston, MA; Braxton D Mitchell, Univ of Maryland Sch of Med, Baltimore, MD; Cecelia A Laurie, Univ of Washington, Seattle, WA; Ramachandran S Vasan, Boston Univ Schs of Public Health and Med, and the Framingham Heart Stud, Boston, MA; Wendy S Post, Johns Hopkins Sch of Med, Baltimore, MD; Patricia A Peyser, Sch of Public Health, Univ of Michigan, Ann Arbor, MI; TOPMed Atherosclerosis Working Group

2:40 PM

Q & A

2:45 PM

An X Chromosome Genetic Association Analysis Identifies Variants in ChrXq23 With Lower Atherogenic Lipids and Lower Risk for Coronary Heart Disease

**Pradeep Natarajan** , Akhil Pampana, Massachusetts General Hosp, Boston, MA; Sarah Graham, Univ of Michigan, Ann Arbor, MI; Derek Klarin, Massachusetts General Hosp, Boston, MA; James Perry, Univ of Maryland, Baltimore, MD; Stephen S Rich, Univ Virginia, Charlottesville, VA; Cristen Willer, Univ of Michigan, Ann Arbor, MI; Gina Peloso, Boston Univ Sch of Public, Boston, MA; on behalf of the NHLBI TOPMed Lipids Working Group

2:50 PM

Q & A

# Moderated Digital Posters

## PH.MDP52 - Pathophysiology of RV Failure, HFpEF and PAH

#### Moderated Posters 2, Science and Technology Hall

### Monday, November 18, 2019, 2:05 PM - 2:55 PM

2:05 PM

Moderator

Elena Goncharova, Pittsburgh, PA

2:05 PM

Reduced Fatty Acid Synthesis Contributes to Diastolic Heart Failure in Mice Exposed to Neonatal Hyperoxia

**Ethan D Cohen** , Min Yee, Univ of Rochester SMD, Rochester, NY; George A Porter Jr., Univ of Rochester Medical Sch, Rochester, NY; Andrew N McDavid, Univ of Rochester SMD, Rochester, NY; Paul S Brookes, Univ of Rochester Medical Ctr, Rochester, NY; Michael O'Reilly, Univ. of Rochester SMD, Dept. of Pediatrics, Div. of Neonatology, Rochester, NY

2:10 PM

Q & A

2:15 PM

GCN2 Regulates Vascular Remodeling in the Pathogenesis of Pulmonary Arterial Hypertension

**Maggie Mengqi Zhu** , Zhiyu Dai, Jingbo Dai, Yi Peng, Youyang Zhao, Northwestern Univ Feinberg Sch of Med, Chicago, IL

2:20 PM

Q & A

2:25 PM

Estrogen Receptor Alpha Protects Against Pulmonary Hypertension Development

**Andrea L Frump** , Bakhtiyor Yakubov, James Hester, Amanda Fisher, Todd Cook, IU Sch of Med, Indianapolis, IN; Suzy Comhair, Cleveland Clinic, Cleveland, OH; Jenny Cheng, Marcela Tabima, Univ of Wisconsin-Madison, Madison, WI; Naomi Claire Chesler, Univ of Wisconsin - Madison, Madison, WI; Tim Lahm, Indiana Univ, Indianapolis, IN

2:30 PM

Q & A

2:35 PM

Gb002, A Novel Inhaled Pdgfr Kinase Inhibitor, Demonstrates Efficacy in the Su5416 Hypoxia Rat Model of Pulmonary Arterial Hypertension (pah)

**Anna Galkin** , Bryan Clemons, Eduardo Garcia, Jennifer Brooks, Debbie Slee, Luisa Salter-Cid, Larry Zisman, Gossamer Bio, San Diego, CA

2:40 PM

Q & A

2:45 PM

Insight Into Right Ventricular Defenses to Pulmonary Hypertension-Associated Pressure Overload: Potential Role of PDZ Protein EBP50

**Maryam Sharifi-Sanjani** , Patricia Riva Marquez, Adam L. Handen, Jeffrey J. Baust, Timothy Bachman, Andrea Sebastiani, Ana Lucia Mora, Stephen Chan, Imad Al Ghouleh, Univ of Pittsburgh, Pittsburgh, PA

2:50 PM

Q & A

# Moderated Digital Posters

## CM.MDP72 - Poop and the Pump: Gut Health, the Microbiome and Cardiometabolic Health

#### Moderated Posters 8, Science and Technology Hall

### Monday, November 18, 2019, 2:05 PM - 2:55 PM

2:05 PM

Protective Effects of Flavonoids on Atherosclerosis Depend on Dietary Fiber and Gut Microbial Colonization

**Kazuyuki Kasahara** , Tzu-Wen L Cross, Eugenio I Vivas, Federico E Rey, Univ Wisconsin Madison, Madison, WI

2:10 PM

Q & A

2:20 PM

Q & A

2:25 PM

Gut Microbiota Modulate the Relationship Between Soy Food Intake, the Metabolome, and Markers of Cardiometabolic Health

Rachana Shah, Children's Hosp of Philadelphia, Philadelphia, PA; **Jane F Ferguson** , Vanderbilt Univ. Medical Ctr, Nashville, TN

2:30 PM

Q & A

2:35 PM

Aging, Diet, and Atherogenesis in Nonhuman Primates

**Mingyi Wang** , NIA/NIH, Baltimore, MD; Edward G Lakatta, Natl Inst on Aging, Baltimore, MD

2:40 PM

Q & A

2:45 PM

Effects of Smoking Cessation on the Intestinal Microbiota

Marcus G Sublette, Univ Wisconsin Med Sch, MADISON, WI; Tzu-wen L Cross, Univ of Wisconsin-Madison, Madison, WI; **Claudia E Korcarz** , Univ Wisconsin Med Sch, Madison, WI; Kristin M Hansen, Univ Wisconsin Med Sch, MADISON, WI; Madeline K Oguss, Federico Rey, Univ of Wisconsin, Madison, WI; James H STEIN, Univ Wisconsin Med Sch, Madison, WI

2:50 PM

Q & A

# Moderated Digital Posters

## AT.MDP60 - Thrombosis and Hemostasis: Mechanisms, Outcomes and Treatment

#### Moderated Posters 4, Science and Technology Hall

### Monday, November 18, 2019, 2:05 PM - 2:55 PM

2:05 PM

Regulation of ITAM Receptor Signaling by Phospholipases PLA2G6 and PNPLA8 in Human Platelets

**Shaji Abraham** , Thomas Jefferson Univ, Philadelphia, PA

2:10 PM

Q & A

2:15 PM

Aberrant Promoter Hypermethylation Mediated Regulation of Thrombomodulin Gene in High Altitude Induced Deep Vein Thrombosis

**Aatira Vijay** , Prabhash Kumar Jha, Defence Inst of Physiology & Allied Sciences, Delhi, India; Seema Parveen, Shailendra Goel, Univ of Delhi, Delhi, India; Amit Prabhakar, Bhuvnesh Kumar, Defence Inst of Physiology & Allied Sciences, Delhi, India; Tathagat Chatterjee, Army Hosp, Delhi, India; Nitin Bajaj, Command Hosp Chandimandir,, Chandigarh, India; Velu Nair, Armed Forces Medical Coll,, Pune, India; Manish Sharma, Defence Inst of Physiology & Allied Sciences, Delhi, India; Mohammad Zahid Ashraf, Jamia Millia Islamia, Jamia Nagar, NEW DELHI, India

2:20 PM

Q & A

2:25 PM

Role of Plasminogen Receptor Histone 2b in Endothelial Cell Migration

**Mitali Das** , Cleveland Clinic, Cleveland, OH; Edward F Plow, Lerner Res Inst Cleveland Clinic, Cleveland, OH

2:30 PM

Q & A

2:35 PM

Point of Care Measurement of Anticoagulation in Patients on Dabigatran, Rivaroxaban and Apixaban Therapy by Novel Automated Thrombelastography

**Ramin Artang** , Essentia Health/St. Mary Hosp, Duluth, MN; Paul A Gurbel, Inova Heart and Vascular, Lutherville, MD; Kevin Bliden, Inova Heart and Vascular Inst, Falls Church, VA; Mark Walsh, Memorial Hosp of South Bend, Sound Bend, IN; Annie Grisoli, Scott Thomas, Memorial Hosp of South Bend, South Bend, IN; Maren Anderson, Univ of Minnesota, Duluth, MN; Jorn Dalsgaard Nielsen, Bispebjerg Univ Hosp, Copenhagen, Denmark; Sarah Greve, Haemonetics Corp., Braintree, MA; Brian C Thurston, Spartanburg Regional Medical Ctr, Spartanburg, SC; Joao Dias, Haemonetics Corp., Signey, Switzerland; Hardeane Achneck, Jan Hartmann, Haemonetics Corp., Braintree, MA

2:40 PM

Q & A

2:45 PM

Calcium-Induced Dissociation of CIB1 From ASK1 Regulates Agonist-Induced Activation of the p38 MAPK Pathway in Platelets

**Pravin Patel** , Meghna Naik, Kalyan Golla, Thomas Jefferson Univ, Philadelphia, PA; Noor Fathima Shaik, Thomas Jefferson Univ, Bensalem, PA; Ulhas Naik, Thomas Jefferson Univ, Philadelphia, PA

2:50 PM

Q & A

# Abstract Oral Session

## AC.AOS.491 - Biomarkers: To STEMI and Beyond!

#### 103A

### Monday, November 18, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Andrew Paul DeFilippis, Louisville, KY

3:45 PM

Moderator

Jennifer E Van Eyk, Los Angeles, CA

3:45 PM

Trimethylamine N-Oxide Levels and Cardiovascular Outcomes in Patients With Prior Myocardial Infarction: Data From PEGASUS-TIMI 54 Trial

**Baris Gencer** , TIMI Study Group, Boston, MA; Xinmin S Li, Cleveland Clinic, Cleveland, OH; Yared Gurmu, TIMI Study Group, Boston, MA; Marc P Bonaca, CPC Clinical Res, Aurora, CO; David A Morrow, TIMI Study Group, Boston, MA; Zeneng Wang, Stanley L Hazen, Cleveland Clinic, Cleveland, OH; Marc S Sabatine, TIMI Study Group, Boston, MA

3:55 PM

Q & A

4:00 PM

High Throughput Targeted Proteomics Discovery Approach to Discover Novel Biomarkers Associated With St-segment Resolution After an St Elevation Myocardial Infarction

**Jay S Shavadia** , Univ Alberta, Edmonton, AB, Canada; Christopher Bull Granger, Duke Clinical Res, Durham, NC; Wendimagegn W Alemayehu, Cynthia M Westerhout, Sean Van Diepen, Univ Alberta, Edmonton, AB, Canada; Thomas J Povsic, Duke Univ Medical Ctr, Chapel Hill, NC; Christopher Defillipi, Inova, Falls Church, VA; Paul W Armstrong, Univ Alberta, Edmonton, AB, Canada

4:10 PM

Q & A

4:15 PM

Circulating Heat Shock Protein 70 as a Prognosis Marker of Stemi

**Thomas Bochaton** , Hop Louis Pradel, LYON, France; Alexandre Paccalet, Inserm U1060, BRON, France; Pierre Jeantet, Hop Louis Pradel, Lyon, France; Claire Crola Ad Silva, Inserm U1060, Bron, France; Claire Jossan, Hop Louis Pradel, Lyon, France; Camille Amaz, Hospices Civils de Lyon, Lyon, France; Delphine Baetz, Inserm U1060, Bron, France; Cyril Prieur, Nathalie Genot, Danka Tomasevic, Hop Louis Pradel, Lyon, France; Nathalie Dufay, Hospices Civils de Lyon, Bron, France; Régine Cartier, Hospices Civils de Lyon, Lyon, France; Gilles Rioufol, Cardiovascular Hosp, Lyon, France; Eric Bonnefoy-Cudraz, Hop Louis Pradel, Lyon, France; Nathan Mewton, Hop Cardiovasculaire L. Pradel, Lyon, France; Michel Ovize, Hospices Civils de Lyon, Lyon, France

4:25 PM

Q & A

4:30 PM

Risk Profile, Antithrombotic Treatment and Clinical Outcomes for Patients in Nordic Countries With Atrial Fibrillation - Results From the Garfield-AF Registry

**Marita Knudsen Pope** , Dan Atar, Oslo Univ Hosp Ullevaal, Oslo, Norway; Arne Svilaas, Oslo Univ Hosp Aker, Oslo, Norway; Torstein Hole, More and Romsdal Hosp Trust, Aalesund, Norway; Eivind Berge, Oslo Univ Hosp, Oslo, Norway; Joern Dalsgaard-Nielsen, Copenhagen Univ Hosp, Copenhagen Univ, Copenhagen, Denmark; Maarten Rosenqvist, Danderyd Univ Hosp, Karolinska Univ Hosp, Stockholm, Sweden; Magnus Schou, Milita Crisby, Karolinska Univ Hosp, Stockholm, Sweden; Pekka Raatikainen, Helsinki Univ Hosp, Tampere, Finland; Juhani Airaksinen, Turku Univ Hosp and Univ of Turku, Turuk, Finland; Laura Illingworth, Children's Hosp Los Angeles, Los Angeles, CA; Karen Pieper, Gloria Kayani, Thrombosis Res Inst, London, United Kingdom; Jean-Yves Le Heuzey, Georges Pompidou Hosp, René Descartes Univ, Paris, France; Jan Steffel, Univ Heart Ctr Zurich, Zurich, Switzerland; Janina Stepinska, Inst of Cardiology, Warsawa, Poland; John Camm, St. George's Univ of London, London, United Kingdom; Jean Pierre Bassand, Univ of Besançon and Thrombosis Res Inst, Besançon, France; Ajey Kumar Kakkar, Thrombosis Res Inst and Univ Coll London, London, United Kingdom

4:40 PM

Q & A

4:45 PM

The Prognostic Significance of Highly Sensitive Cardiac Troponin I Elevation in Patients Presenting With Hypertensive Crisis

Muhammad Talha Ayub, **Christian Torres** , Juan Del Cid, Mohammad Shahzeb Khan, Cook County Health & Hosp System, Chicago, IL; Wajeeha Rasool, AMITA Health Saint Francis Hosp, Evanston, IL; Talha Aijaz, Aakash Putta, Sunny Singh, Rami Doukky, Cook County Health & Hosp System, Chicago, IL

4:55 PM

Q & A

# Abstract Oral Session

## CA.LBBS.AOS.551 - Late-Breaking Basic Science 1

#### 111AB

### Monday, November 18, 2019, 3:45 PM - 5:00 PM

3:45 PM

An Atlas of Transcriptional Diversity in the Human Heart: Analysis of 287,269 Single Cell Transcriptomes From the Four Chambers of the Non-Failing Heart

**Nathan R Tucker** , Massachusetts General Hosp, Boston, MA; Mark Chaffin, Broad Inst, Cambridge; Stephen Fleming, Broad Inst, Cambridge, MA; Amelia Weber Hall, Broad Inst of MIT and Harvard, Cambridge, MA; Victoria Parsons, Massachusetts General Hosp, Boston, MA; Kenneth C Bedi Jr., UNIVERSITY OF PENNSYLVANIA, Philadelphia, PA; Amer-Denis Akkad, Bayer US LLC, Whippany, NJ; Alessandro Arduini, Carolina Roselli, Caroline Herndon, Francois Aguet, Seung Hoan Choi, Kristen Ardlie, Mehrtash Babadi, Broad Inst, Cambridge, MA; Kenneth B Margulies, UNIV PENNSYLVANIA SCH OF MEDICINE, Philadelphia, PA; Christian M Stegmann, BAYER US at Broad Inst, Cambridge, MA; Patrick T Ellinor, MASSACHUSETS GENERAL HOSPITAL, Boston, MA

3:55 PM

Q&A

4:00 PM

Single Cell Sequencing Unveils Profound Changes in Circulating Monocytic Cells in Patients With Heart Failure

**Wesley Abplanalp** , David John, Goethe Univ, Frankfurt am Main, Germany; Birgit Assmus, J. W. Goethe Univ, Frankfurt; Lena Dorsheimer, Goethe Univ, Frankfurt am Main, Germany; Michael Rieger, Goethe Univ Frankfurt, Frankfurt am Main, Germany; Khalil Abou-El-Aradat, Mariuca Vasa-Nicotera, Goethe Univ, Frankfurt am Main, Germany; Andreas M Zeiher, Klinikum d. J. W Goethe-Univ, Frankfurt Am Main; Stefanie Dimmeler, INST OF CARDIOVASULAR REGENERATION, Frankfurt Am Main

4:10 PM

Q&A

4:15 PM

Single Cell Transcriptional Profiling Defines an Intercellular Signaling Network That Organizes the Developing Coronary Vasculature

**Pearl J Quijada** , Jacquelyn A Lillis, Cameron Baker, Jason R Myers, Michael A Trembley, Ronald A Dirkx, UNIVERSITY OF ROCHESTER, Rochester, NY; Ethan D Cohen, UNIVERSITY OF ROCHESTER SMD, Rochester, NY; John M Ashton, UNIVERSITY OF ROCHESTER, Rochester, NY; Eric M Small, UNIVERSITY ROCHESTER, Rochester, NY

4:25 PM

Q&A

4:30 PM

Single-Cell Transcriptomics Reveal PDGF/Snail-Mediated Endothelial Plasticity as a Target for Vessel Normalization Therapy of Myocardial Infarction

Menggui Huang, UNIVERSITY OF PENNSYLVANIA, Philladelphia, PA; Fan Yang, Duo Zhang, Maohuan Lin, Hao Duan, Swapnil Shewale, Yi Fan, **Yanqing GONG** , UNIVERSITY OF PENNSYLVANIA, Philadelphia, PA

4:40 PM

Q&A

4:45 PM

Single Cell Transcriptional Profiling of Aortic Valvuloplasty Balloon Cells Identifies Rare Endothelial Cells

C-hong Chang, Yale Univ, New Haven, CT; Katharine Clapham, Yale New Haven Hosp, New Haven, CT; Chirag A Shah, YALE-NEW HAVEN HOSPITAL, New Haven, CT; Lindsey Prescher, YALE UNIVERSITY SCHOOL MEDICINE, New Haven, CT; Ryan Kaple, Cardiovascular Res Fndn, new york, NY; John K Forrest, Yale Univ, Hamden, CT; Vivian Ng, Columbia Univ, New York, NY; Susheel Kumar Kodali, Columbia Univ Medical Ctr, New York, NY; **Hyung J Chun** , YALE UNIVERSITY SCHOOL MEDICINE, New Haven, CT

4:55 PM

Q&A

# Abstract Oral Session

## MP.AOS.544 - Winter Is Coming... and So Is Cell Death

#### 120A

### Monday, November 18, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Su Huabo

3:45 PM

Moderator

Sebastiano Sciarretta, Latina, Italy

3:45 PM

Ctrp9 Regulates Mitophagic Degradation Against Myocardial Ischemia/rRperfusion Injury Through Modulating Cathepsin Activity

**Dajun Zhao** , Zhongshan Hosp Fudan Univ, Shanghai, China; Wei Yi, Xijing Hosp, The Fourth Military Medical Univ, Xian, China; Wayne Bond Lau, Thomas Jefferson Univ, Philadelphia, PA; Erhe Gao, Lewis Katz Sch of Med at Temple Uni, Philadelphia, PA; Walter J Koch, Thomas Jefferson Univ, Philadelphia, PA; Chunsheng Wang, Zhongshan Hosp Fudan Univ, Shanghai, China; Xin L Ma, Thomas Jefferson Univ, Philadelphia, PA; Yajing Wang, Thomas Jefferosn Univ, Philadelphia, PA

3:55 PM

Q & A

4:00 PM

Alternative Autophagy Protects the Heart Against High Fat Diet-Induced Diabetic Cardiomyopathy

**Mingming Tong** , Peiyong Zhai, Rutgers New Jersey Medical Sch, Newark, NJ; Junichi Sadoshima, Rutgers New Jersey Medical Sch, Neweark, NJ

4:10 PM

Q & A

4:15 PM

N **-ethylmaleimide Sensitive Factor (NSF): A New Regulator of Necrotic Cell Death**

**Emma K Murray** , Alyssa A Lombardi, Temple Univ Medical Sch, Philadelphia, PA; Jonathan P Lambert, Devin Kolmetzky, Temple Univ, Philadelphia, PA; Jeff D Molkentin, Childrens Hosp Med Ctr, Cincinnati, OH; John W Elrod, Temple Univ, Philadelphia, PA

4:25 PM

Q & A

4:30 PM

Impaired NF-kB Signaling Underlies Cyclophilin D Mediated Mitochondrial Permeability Transition Pore Opening in Doxorubicin Cardiomyopathy

**Lorrie A Kirshenbaum** , Rimpy Dhingra, Matthew Guberman, Univ of Manitoba, Winnipeg, MB, Canada; Inna Rabinovich-Nikitin, St. Boniface Res Ctr, Winnipeg, MB, Canada; Jonathon Gerstein, Victoria Margulets, Hongying Gang, James Thliveris, Univ of Manitoba, Winnipeg, MB, Canada

4:40 PM

Q & A

4:45 PM

Activatable Nanoprobe Reveals the Therapeutic Potential of Autophagy Modulation During Cardiotoxic Chemotherapy

**Howard H. Chen** , Tufts Medical Ctr, Boston, MA; Zehedina Khatun, Tufts Medical Ctr, Malden, MA; Choukri Mekkaoui, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Lin Meng, Robert M Blanton Jr., Tufts Medical Ctr, Boston, MA; Hushan Yuan, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Saumya Das, Mass General Hosp, Boston, MA; Lee Josephson, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; David E Sosnovik, Massachusetts General Hosp, Charlestown, MA

4:55 PM

Q & A

# Cardiovascular Seminar

## AT.CVS.137 - Crosstalk Between Lipids and Immune Cells in Cardiovascular Disease

#### 126B

### Monday, November 18, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Marit Westerterp, Groningen, Netherlands

3:45 PM

Moderator

Alison B Kohan, Storrs, CT

3:45 PM

Macrophage Efferocytosis and Atherosclerosis

Edward B Thorp, Chicago, IL

3:55 PM

Q&A

4:00 PM

Pro-resolving Lipid Mediators in Atherosclerosis

Gabrielle Fredman, Albany, NY

4:10 PM

Q&A

4:15 PM

Metabolic Regulation in Immune Cells and Atherosclerosis

Laurent Yvan-Charvet, Nice, France

4:25 PM

Q&A

4:30 PM

Inflammasomes and Atherosclerosis

Marit Westerterp, Groningen

4:40 PM

Q&A

4:45 PM

Immune Checkpoint Inhibitors and Atherosclerosis

Esther Lutgens, Amsterdam

4:55 PM

Q&A

# Cardiovascular Seminar

## NR.CVS.155 - Diabetes and CVD: Stop the Run-Away-Train

#### 113A

### Monday, November 18, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Yvonne Commodore-Mensah, Baltimore, MD

3:45 PM

Moderator

Prakash Deedwania, Fresno, CA

3:45 PM

Halting Onset and Progression of Metabolic Syndrome to Prevent Diabetes and CVD

Matthew Feinstein, Chicago, IL

3:57 PM

Q&A

4:00 PM

Gender Specific Interventions for Diabetes and CVD

Theresa Beckie, Tampa, FL

4:12 PM

Q&A

4:15 PM

Short and Long Term Dietary Interventions

Lynne Braun, Chicago, IL

4:27 PM

Q&A

4:30 PM

Diabetic Medications: Some Old; Some New

Cindy Lamendola, Palo Alto, CA

4:42 PM

Q&A

4:57 PM

Q&A

# Cardiovascular Seminar

## CE.CVS.229 - Maintaining Protein Integrity Under Stress

#### 119AB

### Monday, November 18, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Chris C Glembotski, San Diego, CA

3:45 PM

Moderator

Shirin Doroudgar, Heidelberg, Germany

3:45 PM

UPS in Protein Quality Control

Monte S Willis, Indianapolis, IN

3:55 PM

Q&A

4:00 PM

ATF6 links ER Stress and Cardiac Hypertrophy

Erik Blackwood, San Diego, CA

4:10 PM

Q&A

4:15 PM

Phosphoregulation of the Proteasome

Xuejun Wang, Vermillion, SD

4:25 PM

Q&A

4:30 PM

GRP78 in Heart Disease

Zhao Wang, Dallas, TX

4:40 PM

Q&A

4:45 PM

Protein Quality Control Underlying Afib

Bianca Brundel, Amsterdam

4:55 PM

Q&A

# Cardiovascular Seminar

## PH.CVS.556 - Systems Analyses and Machine Learning in Pulmonary Hypertension: At the Intersection of Computational and Experimental Biology

#### 102AB

### Monday, November 18, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Joseph Loscalzo, Boston, MA

3:45 PM

Moderator

Victoria Parikh, Stanford, CA

3:45 PM

Computational Repurposing of Chemotherapies for Pulmonary Hypertension and Heart Failure

Stephen Y Chan, Pittsburgh, PA

4:00 PM

Fully Automated Imaging Interpretation for Pulmonary Hypertension

Rahul Deo, San Francisco, CA

4:15 PM

Deep Sequencing and EpiGenetic Analysis in Pulmonary Hypertension

Soni Savai, Bad Nauheim

4:30 PM

High-Throughput, Unbiased Metabolomic Analysis in Pulmonary Hypertension and Heart Failure: The Long Road to Mechanism

Mohit Jain

4:45 PM

Extracting High Yield Information From Electronic Health Records in Pulmonary Hypertension

Evan Brittain, Nashville, TN

# Cardiovascular Seminar

## IN.CVS.360 - TAVR in 2019 - Challenging Patient Populations and Uncertainties

#### 112AB

### Monday, November 18, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Peter James Mason, Milwaukee, WI

3:45 PM

Moderator

Nicholas Amoroso, Charleston, SC

3:45 PM

Case Presentation (FELLOW): Valve-Valve-Valve TAVR vs. SAVR case

Sudhi Tyagi, Milwaukee, WI

3:50 PM

Invited Presenter - Valve in Valve, Options, Outcomes and Decision Making

Adnan Chhatriwalla, Kansas City, MO

4:05 PM

Discussion

4:10 PM

CASE Presentation (EARLY CareER): TAVR in an Elderly Patient

Razvan T Dadu, Houston, TX

4:15 PM

Invited Presenter - TAVR in the Elderly, is There Such a Thing as Too Old?

Dharam Kumbhani, Dallas, TX

4:30 PM

Discussion

4:35 PM

CASE Presentation (FELLOW): Low-Risk TAVR Case

Pedro A Villablanca Spinetto, New York, NY

4:40 PM

Invited Presenter - Low-Risk Frontier, Where Do We Stand, What are the Obstacles?

Hans Thyregod, Copenhagen

4:55 PM

Discussion

3:45 PM

Panel Participant

Giorgio Gimelli, Madison, WI

3:45 PM

Panel Participant

Saif Anwaruddin, Philadelphia, PA

3:45 PM

Panel Participant

KELLY EPPS, Washington, DC

# Early Career

## AT.EC.315 - Preparing for Success in Early Career

#### 126A

### Monday, November 18, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Nicholas J Leeper, Stanford, CA

3:45 PM

Moderator

Nathalie Pamir, Portland, OR

3:45 PM

Invited Presenter

Ebru Erbay, Los Angeles, CA

4:00 PM

Q&A

4:05 PM

Invited Presenter

Robert C Bauer, New York, NY

4:20 PM

Q&A

4:25 PM

Invited Presenter

Lale Ozcan, New York, NY

4:40 PM

Q&A

4:45 PM

Invited Presenter

Rebecca Haeusler, New York, NY

# Featured Science

## FS.AOS.08 - How Do (or Don't) New Therapies Work to Reduce CVD Risk? Latest from Recent Trials

#### 103B

### Monday, November 18, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Nancy K Sweitzer, Tucson, AZ

3:45 PM

Influence of Ejection Fraction on the Effect of Treatment in the Dapagliflozin and Prevention of Adverse-Outcomes in Heart Failure Trial (DAPA-HF)

Scott Solomon, Brigham and Women's Hosp, Boston, MA; David L DeMets, Univ of Wisconsin, Madison, WI; Silvio E Inzucchi, Yale Univ Sch of Med, New Haven, CT; Lars Kober, Rigshospitalet, Copenhagen, Denmark; Mikhail N Kosiborod, St. Luke's Health System, Kansas City, MO; Anna Maria langkilde, AstraZenca, Gothenburg, Sweden; Felipe Martinez, Insto Damic, Cordoba, Argentina; Olof Bengtsson, AstraZenca, Gothenburg, Sweden; Piotr Ponikowski, Medical Univ, Wroclaw, Poland; Marc S Sabatine, TIMI Study Group, Boston, MA; Mikaela Sjostrand, AstraZenca, Gothenburg, Sweden; **John J McMurray** , BHF Cardiovascular Res Ctr, Glasgow, United Kingdom

3:53 PM

Timing of Onset of Clinical Benefit with Dapagliflozin in Patients with Heart Failure: An Analysis from the Dapagliflozin and Prevention of Adverse-Outcomes in Heart Failure Trial (DAPA-HF)

**Marc S Sabatine** , TIMI Study Group, Boston, MA; David L DeMets, Univ of Wisconsin, Madison, WI; Silvio E Inzucchi, Yale Univ Sch of Med, New Haven, CT; Lars Kober, Rigshospitalet, Copenhagen, Denmark; Mikhail N Kosiborod, St. Luke's Health System, Kansas City, MO; Anna Maria Langkilde, AstraZenca, Gothenburg, Sweden; Felipe J Martinez, Insto Damic, Cordoba, Argentina; Olof Bengtsson, AstraZenca, Gothenburg, Sweden; Piotr J Ponikowski, Medical Univ, Wroclaw, Poland; Mikaela Sjostrand, AstraZenca, Gothenburg, Sweden; Scott J Solomon, Brigham and Women's Hosp, Boston, MA; John J McMurray, BHF Cardiovascular Res Ctr, Glasgow, United Kingdom

4:01 PM

Empagliflozin Leads to a Rapid and Sustained Improvement of Diastolic Function in Patients With Type 2 Diabetes Independent of Hemodynamic Changes

**Michael Lehrke** , Univ of Aachen, Aachen, Germany; Nikolaus Marx, UK-Aachen, Aachen, Germany; Michael Böhm, Univ Hosp Saarland, Homburg, Germany; Ertunc Altiok, András P Keszei, Univ of Aachen, Aachen, Germany; Alexander Schuh, Univ Hosp Aachen, Aachen; Niels UK Hartmann, Kirsten Thiele, Matthias Rau, Univ of Aachen, Aachen, Germany

4:09 PM

Are the Beneficial Cardiovascular Effects of Glucagon-Like Peptide 1 Receptor Agonists in Diabetic Patients Metabolically Mediated?

**Rafael Diaz** , Noelia Castellana, Andres D Orlandini Sr., Pablo M Lamelas, Maria L Díaz, ECLA - Estudios Clinicos Latino America, Rosario, Argentina; Mark Lackshmanan, Angelyn M Bethel, Indranil Bhattacharya, Eli Lilly and Company, Indianapolis, IN; Hertzel C Gerstein, McMaster Univ and Hamilton Health Sciences, Hamilton, ON, Canada

4:17 PM

Effect of Eicosapentaenoic Acid/Docosahexaenoic Acid on Coronary High-Intensity Plaques Detected With Non-Contrast T1-Weighted Imaging (The AQUAMARINE EPA/DHA Study)

**Teruo Noguchi** , Natl Cerebral & Cardiovascular Ctr, Suita, Japan; Kazuhiro Nakao, Natl Cerebaral and Cardiovascular Ctr, Suita, Japan; Yoshiaki Morita, NCVC, Suita,Osaka, Japan; Yasuhide Asaumi, NCVC, Suita,Osaka, Japan, Suita, Japan; Hiroyuki Miura, NCVC, Suita,Osaka, Japan, Suita, Japan, Suita, Japan; Haruko Yamamoto, Natl Cerebral & Cardiovascular Ctr, Osaka, Japan; Satoshi Yasuda, Natl Cereb Cardiovascular Ctr, Osaka, Japan

4:25 PM

Coronary Flow Reserve, Myocardial Mechanics and Inflammation in Patients With Coronary Artery Disease Enrolled in the Cardiovascular Inflammation Reduction Trial

**Viviany R Taqueti** , Brigham and Women's Hosp, Harvard Medical Sch, Boston, MA; Amil M Shah, Brendan M Everett, Aruna D Pradhan, Brigham and Women's Hosp, Boston, MA; Gregory Piazza, BWH, Boston, MA; Courtney Bibbo, Jon Hainer, Brigham and Women's Hosp, Boston, MA; Victoria Morgan, Laurel Campbell, Hicham Skali, Ron Blankstein, Sharmila Dorbala, Brigham and Women's Hosp, Boston, MA; Samuel Z Goldhaber, Cardiovascular Div, Boston, MA; Michel R Le May, Univ of Ottawa Heart Inst, Ottawa, ON; Benjamin J.w. Chow, Robert deKemp II, Univ of Ottawa Heart Inst, Ottawa, ON, Canada; Fadi G Hage, Univ of Alabama Birmingham, Birmingham, AL; Rob S Beanlands, Univ of Ottawa Heart Inst, Ottawa, ON, Canada; Robert J Glynn, Brigham and Women's Hosp, Boston, MA; Scott Solomon, Brigham and Women's Hosp / Harvard Univ, Boston, MA; Paul M Ridker, Marcelo F Di Carli, Brigham and Women's Hosp, Boston, MA

4:33 PM

Omega-3 Fatty Acids and Risk of Cardiovascular Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials With 127,447 Individuals and a Mendelian Randomization Study

Mohsen Mazidi, King's Coll London, London, United Kingdom; Dimitri P Mikhailidis, Univ Coll London (UCL), London, UK, London, United Kingdom; **Maciej Banach** , Medical Univ of Lodz, Lodz, Poland

# Main Event

## CS.ME.1618 - Trending Topics in Basic Science

#### Nutter Theatre

### Monday, November 18, 2019, 3:45 PM - 5:00 PM

3:45 PM

Moderator

Yabing Chen, Birmingham, AL

3:45 PM

Moderator

Steven P Jones, Louisville, KY

3:45 PM

Trending Topics in Cardiac Development, Structure and Function

Lina A Shehadeh, Miami, FL

3:55 PM

Trending Topics in Arteriosclerosis, Thrombosis, Vascular Biology

Alan Daugherty, Lexington, KY

4:05 PM

Trending Topic in Cellular Biology

John W Elrod, Philadelphia, PA

4:15 PM

Trending Topics in Metabolism & Physiology

Anja Karlstaedt, Houston, TX

4:25 PM

Trending Topics in Drug Discovery and Signaling

Maria Irene Kontaridis, Utica, NY

4:45 PM

Panel Discussion

# Abstract Oral Session

## CA.LBBS.AOS.553 - Late-Breaking Basic Science 2

#### 111AB

### Monday, November 18, 2019, 5:30 PM - 6:30 PM

5:30 PM

Efficacy and Safety Data on Novel Oral Proprotein Convertase Subtilisin-Kexin Type 9 Antagonist

**Nabil A Elshourbagy M** , SHIFA BIOMEDICAL CORPORATION, West Chester, PA; kavitha godugu, Pharmaceutical Res Inst, Renessealer, NY; Kazutoshi Fujioka M, Weikun Li M, Pharmaceutical Res Inst, Rensselaer, NY; Harold V Meyers M, SHIFA BIOMEDICAL CORPORATION, West Chester, PA; Sherin S Abdel-Meguid M, SHIFA BIOMEDICAL CORPORATION, Malvern, PA; Shaker A Mousa, PHARMACEUTICAL RESEARCH INST, Rensselaer, NY

5:40 PM

Q&A

5:45 PM

The E3 Ubiquitin Ligase Hectd3 is a Novel Regulator of Cardiac Hypertrophy and Inflammation

**Ashraf Y Rangrez** , Ankush Borlepawar, Nesrin Schmiedel, Anushka Deshpande, Lynn Christen, Alexander Bernt, UNIVERSITY MEDICAL CENTER KIEL, Kiel, Germany; Manju Kumari, UKE, Hamburg, Germany; Anca Remes, UNIVERSITY MEDICAL CENTER KIEL, Kiel, Germany; Andreas Helbig, CHRISTIAN-ALBRECHTS UNIVERSITY KIEL, Kiel, Germany; Andreas Jungmann, UNIVERSITY MEDICAL CENTER Heidelberg, Heidelberg, Germany; Samuel T Sossalla, UNIVERSITY MEDICAL CENTER REGENSBURG, Regensburg, Germany; Andreas Tholey, CHRISTIAN-ALBRECHTS UNIVERSITY KIEL, Kiel, Germany; Oliver J Mueller, Derk Frank, Norbert Frey, UNIVERSITY MEDICAL CENTER KIEL, Kiel, Germany

5:55 PM

Q&A

6:00 PM

Autoantibodies to Actin, Keratin and Connexin Are a Sensitive Biomarker for Brugada Syndrome

Diptendu Chatterjee, Hosp for Sick Children, Toronto, ON, Canada; Maurizio Pieroni, San Donato Hosp, Cardiovascular Dept, Arezzo, Italy; Meena Fatah, The Hosp for Sick Children, Toronto, ON, Canada; Flavien Charpentier, L'Inst Du Thorax, Nantes, France; Kris S Cunningham, Univ of Toronto Dept of Lab Med and Pathobiology, Toronto, ON, Canada; Danna Spears, Univ Health Network, Toronto, ON, Canada; Dipa Chatterjee, Univ of Toronto, Toronto, ON, Canada; Gonca Suna, Univ Hosputal, Zurich, Switzerland; Pasquale Notarstefano, Leonardo Bolognese, San Donato Hosp, Cardiovascular Dept, Arezzo, Italy; Firat Duru, Univ Heart Ctr Zurich, Zurich, Switzerland; Ardan M Saguner, Univ Hosp Zurich, Zurich, Switzerland; **Robert M Hamilton** , Hosp for Sick Children, Toronto, ON, Canada

6:10 PM

Q&A

6:15 PM

Inhibition of Coagulation Factor XI Suppress Progression of Atherosclerosis

**Anh T. Ngo** , Oregon Health And Science Univ, Portland, OR; Cristina Puy, Portland, OR; Jiaqing Pang, Oregon Health And Science Univ, Portland, OR; Erik I Tucker, ARONORA, Portland, OR; Christina U Lorentz, ARONORA INC, Portland, OR; Norah G Verbout, Aronora, Inc., Portland, OR; Kelley Jordan, Oregon Health And Science Univ, Portland, OR; Paul A Mueller, Oregon Health and Science Universit, Portland, OR; Alexey S. Revenko, Brett P. Monia, IONIS Pharmaceuticals, Carlsbad, CA; Andras Gruber, Owen J. McCarty, Oregon Health & Science Univ, Portland, OR; Hagai Tavori, OHSU, Portland, OR

6:25 PM

Q&A

# Abstract Oral Session

## IN.AOS.489 - Novel Approaches in Interventional Cardiology

#### 204C

### Monday, November 18, 2019, 5:30 PM - 6:45 PM

5:30 PM

The Association of Hospital and Operator Volumes With Procedural Success Rates and Outcomes in Patients Undergoing Percutaneous Coronary Interventions for Chronic Total Occlusions: Insights From the Blue Cross Blue Shield of Michigan Cardiovascular Consortium

**Rami Kassem Zein** , St. John Hosp and Medical Ctr, Detroit, MI; Milan Seth, Univ of Michigan, Ann Arbor, MI; Khaldoon Alaswad, Henry Ford Cardiovascular Div, Birmingham, MI; Hussein Othman, St. John Hosp and Medical Ctr, Detroit, MI; Dan Menees, Univ of Michigan Medical Ctr, Ann Arbor, MI; Howard S Rosman, St. John Medical Ctr, Detroit, MI; Thomas LaLonde, Eastlake CV Associates, St. Clair Shores, MI; Edouard Daher, St. John Hosp and Medical Ctr, Detroit, MI; Rajendra H Mehta, Duke Clinical Res Inst, Durham, NC; Hitinder S Gurm, Univ of Michigan, Ann Arbor, MI

5:40 PM

Q & A

5:45 PM

Radial Access Use for Percutaneous Coronary Intervention in Dialysis Patients

**Nadia R Sutton** , Milan Seth, Univ Michigan, Ann Arbor, MI; Hitinder S Gurm, Univ of Michigan, Ann Arbor, MI

5:55 PM

Q & A

6:00 PM

Quantitative Assessment of Vascular Response After Drug-Eluting Stent Implantation in Patients: A Polarization-Sensitive Optical Frequency Domain Imaging Study

**Kenichiro Otsuka** , Martin Villiger, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Laurens J.C. van Zandvoort, Joost Daemen, Erasmus Univ Medical Ctr, Rotterdam, Netherlands; Antonios Vasileios Karanasos, Hippokration Hosp, Athens, Greece; Gijs van Soest, Erasmus Univ Medical Ctr, Rotterdam, Netherlands; Jouke Dijkstra, Leiden Univ Medical Ctr, Leiden, Netherlands; Seemantini Nadkarni, Massachusetts General Hosp, Harvard Medical Sch, Boston, MA; Evelyn Regar, Univ Hosp Zurich, Zurich, Switzerland; Brett E. Bouma, Massachusetts General Hosp, Boston, MA

6:10 PM

Q & A

6:25 PM

Q & A

6:30 PM

Evolution of Metallic Scaffolds for Cardiovascular Stents

**Donghui Zhu** , Stony Brook Univ, Stony Brook, NY

6:40 PM

Q & A

# Abstract Oral Session

## CE.AOS.542 - So Many Ways for the Heart to Fail, But So Few to Rescue It

#### 120A

### Monday, November 18, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Shahid P Baba, Louisville, KY

5:30 PM

Brown Adipose Tissue Dysfunction Promotes Metabolic Disorder in a Failing Heart

Yohko Yoshida, Nigata Univ Sch of Med, Niigata, Japan; **Ippei Shimizu** , Tohru Minamino, Nigata Univ, Niigata, Japan

5:40 PM

Q & A

5:45 PM

A Novel Metric of Myocardial Compressibility Differentiates Amyloid, Hypertrophic and Dilated Cardiomyopathy From Normal

**Alexander J Ryu** , Vinayak Kumar, Armando Manduca, Nandan S Anavekar, Mayo Clinic, Rochester, MN

5:55 PM

Q & A

6:00 PM

Age-Specific Expression of Serum Response Factor Deletion 5 Isoform Affects Cardiomyocyte Calcium Reuptake and Whole Cell Relaxation

**Kathleen C Woulfe** , Danielle A Jeffrey, Cortney E Wilson, Jennifer H Mahaffey, Univ of Colorado, Aurora, CO; Brian L Stauffer, Univ Colorado Denver, Aurora, CO; Shelley D Miyamoto, Childrens Hosp Colorado, Aurora, CO; Carmen C Sucharov, Univ of Colorado Denver, Aurora, CO

6:10 PM

Q & A

6:15 PM

The Late Sodium Current Modulates Diastolic Function

**Daniel O Cervantes** , Jessica Dorilio, Eleonora Cianflone, New York Medical Coll, Valhalla, NY; Marianna Meo, IHU Liryc, Electrophysiology and Heart Modeling Inst, Bordeaux, France; Thomas J Hund, The Ohio State Univ, Columbus, OH; Olivier Meste, Univ de Nice-Sophia Antipolis, Nice-Sophia Antipolis, France; Jason T Jacobson, Marcello Rota, New York Medical Coll, Valhalla, NY

6:25 PM

Q & A

6:30 PM

**Upregulation of Cardiac Beta** 3 **-Adrenergic Signaling Promotes Cardiac Aging: Evidence from Chronic Beta** 3 **-Adrenoceptor Deficiency Mice**

**Zhe Chen** , Che Ping Cheng, Peng Zhou, Yixi Liu, Zhi Zhang, Satoshi Masutani, Michael F. Callahan, Dalane Kitzman, Heng-Jie Cheng, Wake Forest Sch of Med, Winston-Salem, NC

6:40 PM

Q & A

# Cardiovascular Seminar

## CA.CVS.213 - Making Spare Parts - Engineered Tissue for Cardiac Repair

#### 119AB

### Monday, November 18, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Sean M Wu, Stanford, CA

5:30 PM

Moderator

Ngan F Huang, Stanford, CA

5:30 PM

3D Bioprinting for Engineering Vascularized Tissues

Jordan Miller, Houston, TX

5:40 PM

Q & A

5:45 PM

Engineering of Vascularized Tissues for Treatment of Tissue Ischemia

Ngan F Huang, Stanford, CA

5:55 PM

Q & A

6:00 PM

Engineered Cardiac Tissue With Novel Technology and Biomatrices

Elizabeth Lipke, Baltimore, MD

6:40 PM

Q & A

6:15 PM

Engineering Striated Muscle for Optimal Contractile Function

Nenad Bursac, Durham, NC

6:10 PM

Q & A

6:30 PM

3D Imaging of Trabecular Tissue Engineering

Rene R Packard, Glendale, CA

6:25 PM

Q & A

# Cardiovascular Seminar

## ST.CVS.129 - Patient-Centered Strategies to Improve Outcomes in Atrial Fibrillation

#### 112AB

### Monday, November 18, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Megan M Streur, Seattle, WA

5:30 PM

Moderator

Jeroen M.L. Hendriks, Adelaide, Australia

5:30 PM

Exercise, Weight Loss, and Risk-factor Management in AF

Signe Risom, Copenhagen

5:45 PM

Pathways to Reduce the Risk of Stroke in Silent and Symptomatic AF

Deirdre A Lane, Liverpool

6:00 PM

Engagement in Self-Management Strategies to Improve Patient-centered Outcomes in AF

Linda Ottoboni, San Fransisco, CA

6:15 PM

AF Toolkit: What Patients Need to Know About AFib

Pamela J McCabe, Rochester, MN

6:30 PM

Discussion

# Hybrid

## AT.HB.471 - Fighting the Fire of Inflammation: Yay or Nay?

#### 126A

### Monday, November 18, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Christie M Ballantyne, Houston, TX

5:30 PM

Moderator

Katey Rayner, Ottawa, ON, Canada

5:30 PM

Vote: Yay or Nay

5:35 PM

Atherosclerosis is an Inflammatory Disease: Fighting the Inflammation in the Clinic

Peter Libby, Boston, MA

5:45 PM

Epidemiology of Inflammation and Atherosclerosis

Jennifer G Robinson, Iowa City, IA

5:55 PM

Race-Specific Lipid and Inflammation Profiles in Relation to Coronary Heart Disease

**Cesar Tejera Higgins** , Oregon Health & Science Univ, Portland, OR; Neil Zakai, Univ of Vermont, Colchester, VT; Jessica Minnier, Oregon Health & Science Univ, Portland, OR; Sergio Fazio, Oregon, Portland, OR; Monika Safford, Lisandro Colantonio, Cornell Univ, New York, NY; Marguerite M Irvin, Univ Alabama Birmingham, Birmingham, AL; Virginia J Howard, Univ of Alabama Birmingham, Birmingham, AL; Nathalie Pamir, Oregon Health & Science Univ, Portland, OR

6:10 PM

Bacteroides **Protect Against Atherosclerosis by Regulating Gut Microbial Lipopolysaccharide Production**

**Naofumi Yoshida** , Kobe Univ Graduate Sch, Kobe-city, Japan; Tomoya Yamashita, Kobe Univ, Kobe, Japan; Takuo Emoto, Tokiko Tabata, Yoshihiro Saito, Kobe Univ Graduate Sch, Kobe-city, Japan; Hikaru Watanabe, Takuji Yamada, Tokyo Inst of Technology, Tokyo, Japan; Ken-ichi Hirata, Kobe Univ Graduate Sch, Kobe-city, Japan

6:20 PM

Q & A and Panel Discussion

6:40 PM

Vote: Yay or Nay

# Hybrid

## AT.HB.472 - Lipid Lowering and Lipoprotein Function in Clinical Studies

#### 126B

### Monday, November 18, 2019, 5:30 PM - 6:45 PM

5:30 PM

Moderator

Henry N Ginsberg, New York, NY

5:30 PM

Lipid Lowering and Lipoprotein Function: From Bench to Bedside

Sergio Fazio, Portland, OR

5:40 PM

Q & A

5:55 PM

Q & A

6:00 PM

Enhanced Roles of Cholesterol Efflux Capacity in Coronary Atheroma Regression in Patients Achieving Targets for Cardiovascular Risk

**Kohei Takata** , SAHMRI, Adelaide, Australia; Jordan Andrews, SAHMRI, Adelaide, SA, Australia; Gijo Thomas, SAHMRI, Adelaide, Australia; Julie Butters, SAHMRI, Adelaide, SA, Australia; Daisuke Shishikura, Giuseppe Di Giovanni, SAHMRI, Adelaide, Australia; Stephen Nicholls, Monash Cardiovascular Res Ctr, Melbourne, Australia

6:10 PM

Q & A

6:15 PM

Alirocumab Reduces Total Hospitalizations and Increases Days Alive and Out of Hospital in the ODYSSEY OUTCOMES Trial

**Michael Szarek** , SUNY Downstate Sch of Public Health, Brooklyn, NY; Philippe Gabriel Steg, Hop Bichat, Paris, France; Dina DiCenso, Woodhull Medical Ctr, Brooklyn, NY; Deepak L Bhatt, Brigham and Women's Hosp, Boston, MA; Vera A Bittner, Univ of Alabama at Birmingham, Birmingham, AL; Andrzej Budaj, Postgraduate Medical Sch, Grochowski Hosp, Warsaw, Poland; Rafael Diaz, Estudios Clínicos Latinoamérica, Rosario, Argentina; Shaun Geoffrey Goodman, St Michael's Hosp, Toronto, ON, Canada; Nina Gotcheva, MHAT "Natl Cardiology Hosp" EAD, Sofia, Bulgaria; J Wouter Jukema, Leiden Univ Medical Ctr, Leiden, Netherlands; Robert Pordy, Regeneron Pharmaceuticals, Tarrytown, NY; Matthew T Roe, Duke Clinical Res Inst, Durham, NC; Timothée Sourdille, Sanofi, Bridgewater, NJ; Harvey D White, Auckland City Hosp, Auckland, New Zealand; Denis Xavier, St. Johns Medical Coll, Bangalore, India; Andreas M Zeiher, Klinikum d. J. W Goethe-Univ, Frankfurt Am Main; Gregory G Schwartz, Univ of Colorado Sch of Med, Aurora, CO; for the ODYSSEY OUTCOMES Investigators

6:25 PM

Q&A

6:30 PM

Safety, Tolerability and LDL-C Reduction With LIB003 a Novel Anti-PCSK9 Recombinant Fusion Protein: Results of Open-Label Extension Phase 2B Study

**Evan A Stein** , LIB Therapeutics, Cincinnati, OH; Traci Turner, Medpace, Cincinnati, OH; Dean J Kereiakes, Ohio Heart Health Ctr, Cincinnati, OH; Bain Butcher, Padma Mangu, Sterling Res, Cincinnati, OH; Rong Zhou, Medpace, Cincinnati, OH

6:40 PM

Q&A
