Genome editing is said to be done when targeted
changes like insertions and deletions are
made right in an organism's genome. Over past
few decades CRISPR CAS-9 system has become
very popular genome editing method because
it is fast,cheap and precise and also relatively
easy to use. In,this system researchers create
a piece of RNA guide sequence which is complentary
to replace the DNA in host's genome. The Cas-9
protein then attaches with the RNA complex
guide and whole thing got bind towards DNA
in host's genome the Cas-9 RNA complex than
make a double strand cut in DNA of host's
genome. So that' an alternative piece of RNA
guide be spliced right at the same spot. This
technology in variety of cells and organisms
and its also been used to study disease generate
tissue and neuronal tissues. Not only that
much it is even possible to treat a whole
multicellular organism using CRISPR CAS-9
genome editing method. Not even that much,
many of whole multicellular organisms such
as like mice , horse and monkey have been
treated using this system. Recently a chinese
scientist named " He jiankui " have claimed
that he can do this editing even in humans
. Isn't it seems weird ?
As a certain ,we can only edit somatic cells
using CRISPR CAS-9 genome editing or any other
genome editing method . But what, if we can
edit germline cells using genome editing method
?the engineered changes can easily passed
for the next generation. Which means : human
civilization will be one step forward to gain
immortality .
Wait,wait,wait, and at the last . My name
is Abhijeet and Abhijeet means undefeatable
in Nepali. And, human civilization can also
be undefeatable to death by using C CRISPR
CAS-9 system or genome editing.
