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Engineering HSC and
IIT-JEE Mains and advanced videos.Hello student Today we
are studying chapter change its nature
expression and recognition in that we
are studying topic Central Dogma
molecular biology is basically based on
certain parameters for example first DNA
will come then mRNA them and then
protein mythical this is central dogma
we'll be starting today about this
we all have started with the formation
of proteins in LA now when we study
protein synthesis we started from DNA we
all know that DNA is our genetic
material every cell you know what you
will have DNA if that is really not
present inside your body then proteins
won't be synthesize because the
information to synthesize or to make
those proteins for example if you have
to make insulin in your body then that
information has to be present on DNA
strand from DNA in the process of
replication will help to form DNA and
from DNA once a no DNA is copied and
mRNA is form that process is called as
transcription after transcription has
taken place then translation will help
to form protein and during the process
of translation all the three different
types of non-genetic RNA which is your
mRNA that's messenger RNA ribosomal RNA
which is RNA and transfer RNA that's
tree or it takes pass so the central
dogma theory says that first DNA will
come then all the different kinds of
mRNA will come and finally your protein
now every prokaryotic organism follows
this theory but that is one organism
which reverse the center of Metheny
which is your HIV virus or the worse
transcriptase now HIV or the worst
transcriptase is having an ability with
the help of enzyme that it can convert
the single-stranded RNA
towards DNA which is the reverse of
central dogma the central dogma says DNA
RNA and then protein but HIV can follow
just the reverse of that it can make RNA
into DNA now the center of the theory
was basically given by Francis Haley and
center of my place very crucial rule
during protein synthesis
central rock material now this central
dogma theory was formulated by English
balances Francis Harry Compton the
central dogma theory basically states
that the flow of genetic information is
unidirectional or genetic basically
works in one direction that is first DNA
will be synthesized or deoxyribose
nucleic acid will be fun then RNA which
is ribose nucleic acid in form and then
your polypeptide chain or proteins will
be fun
the exception to central dogma theory
that is DNA then RNA then protein is
just your reverse transcriptase enzyme
just present in HIV we all know whenever
HIV attacks human body the reverse
transcriptase present inside HIV
converts the single-stranded RNA present
in HIV into the double-stranded DNA and
then once the DNA matches from your body
to the HIV is body then HIV calm
perséfone basically it converts it
already into double-stranded DNA and
your double-stranded DNA and it's our
standard unit will now look similar
so HIV is an exception to central dogma
the simple diagrammatic representation
of central dogma could be this diagram
that is replication helps to form DNA
just double-stranded DNA then DNA
undergoes the process of transcription
and forms mRNA or we can say messenger
RNA containing all the genetic
information to make the proteins during
the process of translation all the three
different mRNAs mrna R&E trna comes
together to form the protein or
polypeptide chain so the journey from
DNA to the journey of insulin formation
is nothing but you can say central dogma
which is never betrayed in eukaryotic
organisms until illness there are
mutations or some genetic problems
students in this part of the chapter we
have started about central dogma and how
does central um basically functions and
its properties I hope you are not clear
about this concept thank you
