NARRATOR: FDA worked with
scientists and doctors
at Joanneum Research in
Austria to develop a new method
for assessing the bioequivalence
of topical drugs, a key step
in approval of generic versions.
Dermal open-flow
microperfusion allows
scientists to measure
concentrations of topical drugs
within the skin.
Here's how it works: A
narrow, semi-porous tube
is inserted just under
the skin surface.
A liquid is injected
into the tube.
The drug that is absorbed
by the skin's outer layers
enters the flowing
liquid in a tube.
The liquid is
collected for analysis.
This novel sampling
method is designed
to demonstrate
the bioequivalence
of topical medications.
Having increased
access to generic drugs
could benefit the
millions of Americans
who have skin diseases.
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